MGI PRS for Breast cancer [female](174.1) based on UKB GWAS (FINNGEN) | ||
GWAS reference: !UKB_GWAS | GWAS source: UKB GWAS (FINNGEN) | PRS method: Lassosum |
PRSweb LD reference: UKB | GWAS phenotype: Malignant neoplasm of breast | PRSweb date: 2020-06-20 |
GWAS ID: C3_BREAST_3 | GWAS URL: http://www.nealelab.is/uk-biobank | Genome build: GRCh37/hg19 |
PRS tuning parameter: s=0.5;Lambda=0.01833 | PRS evaluation in: MGI |
Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression.
The corresponding confidence intervals are also shown. Results from PRS PheWAS (blue) and Exclusion PRS PheWAS (red) are presented for models using either
a continuous or a categorical version of the PRS. Q1 through Q4 represent the four quartiles of the PRS.