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MGI PRS for Lymphoid leukemia, chronic(204.12) based on UKB GWAS (PheCode)
GWAS reference: UKB_GWAS GWAS source: UKB GWAS (PheCode) PRS method: Lassosum
PRSweb LD reference: UKB GWAS phenotype: Lymphoid leukemia, chronic PRSweb date: 2020-06-20
GWAS ID: UKBB_SAIGE_HRC_X204.12 GWAS URL: ftp://share.sph.umich.edu/UKBB_SAIGE_HRC/ Genome build: GRCh37/hg19
PRS tuning parameter: s=0.5;Lambda=0.1 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.8054 1.01 0.963,1.05 2317 23065 0.4375 0.973 0.909,1.04 910 9173
008.5 Bacterial enteritis infectious diseases Both 0.2296 0.962 0.904,1.02 1090 10875 0.5433 0.978 0.911,1.05 842 8794
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.6887 0.986 0.92,1.06 896 8939 0.5433 0.978 0.911,1.05 842 8794
008.6 Viral Enteritis infectious diseases Both 0.4498 1.03 0.95,1.12 590 5900 0.2972 1.05 0.961,1.14 569 5816
010 Tuberculosis infectious diseases Both 0.5546 1.04 0.905,1.2 195 1948 0.2404 0.988 0.968,1.01 18625 19188
031 Diseases due to other mycobacteria infectious diseases Both 0.2307 1.15 0.914,1.45 73 722 0.2618 1.14 0.904,1.45 70 712
038 Septicemia infectious diseases Both 0.3076 1.02 0.978,1.07 2043 20052 0.826 0.992 0.926,1.06 885 9359
038.1 Gram negative septicemia infectious diseases Both 0.6934 1.02 0.927,1.12 459 4559 0.9795 1.0 0.906,1.11 416 4493
038.2 Gram positive septicemia infectious diseases Both 0.4009 0.936 0.801,1.09 184 1840 0.2685 0.913 0.777,1.07 170 1821
038.3 Bacteremia infectious diseases Both 0.9141 1.0 0.939,1.07 955 9489 0.826 0.992 0.926,1.06 885 9359
041 Bacterial infection NOS infectious diseases Both 0.7413 0.995 0.964,1.03 4641 32299 0.3243 1.07 0.934,1.23 211 2240
041.1 Staphylococcus infections infectious diseases Both 0.7499 1.01 0.955,1.07 1390 13828 0.1256 1.07 0.982,1.16 617 6294
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.5224 0.975 0.903,1.05 714 7071 0.5333 0.975 0.901,1.06 685 6993
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.0871 1.07 0.99,1.16 639 6376 0.1256 1.07 0.982,1.16 617 6294
041.2 Streptococcus infection infectious diseases Both 0.5297 1.02 0.962,1.08 1316 13131 0.1982 1.1 0.952,1.27 204 2012
041.21 Rheumatic fever / chorea infectious diseases Both 0.166 1.11 0.959,1.28 205 2047 0.1982 1.1 0.952,1.27 204 2012
041.4 E. coli infectious diseases Both 0.5395 1.02 0.955,1.09 949 9462 0.7278 1.01 0.945,1.08 904 9352
041.8 H. pylori infectious diseases Both 0.04571 0.858 0.737,0.997 190 1892 0.04074 0.852 0.732,0.993 186 1860
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.2793 1.08 0.942,1.23 228 2265 0.3243 1.07 0.934,1.23 211 2240
053 Herpes zoster infectious diseases Both 0.3236 1.03 0.971,1.09 1184 11746 0.04898 1.17 1.0,1.37 158 1629
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.05888 1.16 0.995,1.36 166 1655 0.04898 1.17 1.0,1.37 158 1629
054 Herpes simplex infectious diseases Both 0.2825 1.03 0.974,1.1 1235 12278 0.2679 1.03 0.974,1.1 1188 12166
070 Viral hepatitis infectious diseases Both 0.9462 1.0 0.926,1.09 661 6584 0.6531 1.02 0.948,1.09 894 9115
070.1 Viral hepatitis A infectious diseases Both 0.2148 1.17 0.912,1.51 67 660 0.2173 1.17 0.911,1.51 67 653
070.2 Viral hepatitis B infectious diseases Both 0.9354 0.994 0.852,1.16 162 1620 0.929 1.01 0.862,1.18 157 1603
070.3 Viral hepatitis C infectious diseases Both 0.5082 0.967 0.876,1.07 439 4366 0.5458 0.969 0.876,1.07 425 4319
070.4 Chronic hepatitis infectious diseases Both 0.6531 0.964 0.82,1.13 161 1610 0.881 0.988 0.838,1.16 154 1594
070.9 Hepatitis NOS infectious diseases Both 0.7568 1.01 0.945,1.08 924 9231 0.6531 1.02 0.948,1.09 894 9115
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.6471 1.05 0.864,1.26 122 1220 0.1 1.2 0.966,1.48 94 942
071.1 HIV infection, symptomatic infectious diseases Both 0.1074 1.19 0.962,1.48 95 950 0.1 1.2 0.966,1.48 94 942
078 Viral warts & HPV infectious diseases Both 0.208 1.03 0.986,1.07 2651 24185 0.2254 1.03 0.985,1.07 2578 23959
079 Viral infection infectious diseases Both 0.2028 1.02 0.99,1.05 5061 29504 0.9795 1.0 0.919,1.09 561 5663
079.1 Varicella infection infectious diseases Both 0.008318 1.05 1.01,1.09 2940 25647 0.01622 1.05 1.01,1.09 2834 25373
079.2 Infectious mononucleosis infectious diseases Both 0.7621 0.978 0.849,1.13 213 2093 0.9727 1.0 0.869,1.16 206 2082
079.9 Viremia, NOS infectious diseases Both 0.9727 0.999 0.917,1.09 579 5713 0.9795 1.0 0.919,1.09 561 5663
080 Postoperative infection infectious diseases Both 0.2094 0.974 0.936,1.01 2586 25769 0.1858 0.973 0.934,1.01 2532 25435
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.859 0.995 0.941,1.05 1364 13616 0.8995 0.996 0.941,1.06 1290 13445
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.2489 1.05 0.969,1.13 700 6990 0.2421 1.05 0.969,1.13 684 6911
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.2685 1.02 0.982,1.07 2379 23308 0.2265 0.918 0.798,1.05 219 2196
110.1 Dermatophytosis infectious diseases Both 0.0631 1.04 0.998,1.09 2164 21163 0.0871 1.08 0.989,1.18 555 5611
110.11 Dermatophytosis of nail infectious diseases Both 0.2143 1.04 0.979,1.1 1264 12489 0.3334 1.03 0.971,1.09 1230 12309
110.12 Althete's foot infectious diseases Both 0.02455 1.1 1.01,1.19 593 5884 0.01778 1.11 1.02,1.2 571 5797
110.13 Dermatophytosis of the body infectious diseases Both 0.104 1.07 0.985,1.17 570 5682 0.0871 1.08 0.989,1.18 555 5611
110.2 Dermatomycoses infectious diseases Both 0.139 0.911 0.806,1.03 283 2812 0.1786 0.919 0.812,1.04 279 2784
112 Candidiasis infectious diseases Both 0.1919 1.03 0.987,1.07 2931 25310 0.5129 1.03 0.942,1.13 531 5385
112.3 Candidiasis of skin and nails infectious diseases Both 0.415 1.04 0.95,1.13 546 5450 0.5129 1.03 0.942,1.13 531 5385
117 Mycoses infectious diseases Both 0.9931 1.0 0.912,1.1 494 4925 0.01738 0.763 0.611,0.954 89 1026
117.1 Histoplasmosis infectious diseases Both 0.2133 1.17 0.914,1.5 66 660 0.1663 1.19 0.929,1.54 62 650
117.4 Aspergillosis infectious diseases Both 0.1069 0.846 0.69,1.04 105 1045 0.01738 0.763 0.611,0.954 89 1026
130 Spirochetal infection infectious diseases Both 0.06918 0.835 0.687,1.01 118 1177 0.02884 0.772 0.613,0.974 84 846
130.1 Lyme disease infectious diseases Both 0.06607 0.809 0.645,1.01 86 860 0.02884 0.772 0.613,0.974 84 846
132 Infestation (lice, mites) infectious diseases Both 0.3698 1.08 0.913,1.28 146 1460 0.4093 1.07 0.906,1.27 143 1443
134 Helminthiases infectious diseases Both 0.7362 0.954 0.724,1.26 54 540 0.8433 0.973 0.737,1.28 52 532
136 Other infectious and parasitic diseases infectious diseases Both 0.8974 1.0 0.962,1.05 2438 24314 0.7852 1.01 0.964,1.05 2347 24002
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.8414 0.994 0.936,1.06 1166 11657 0.955 0.998 0.939,1.06 1133 11431
145 Cancer of mouth neoplasms Both 0.1014 1.05 0.99,1.11 1182 11759 0.7638 0.976 0.834,1.14 167 1701
145.1 Cancer of lip neoplasms Both 0.05754 1.26 0.993,1.6 69 690 0.0871 1.23 0.97,1.57 68 682
145.2 Cancer of tongue neoplasms Both 0.4875 1.03 0.946,1.12 550 5486 0.5794 1.02 0.939,1.12 542 5388
145.3 Cancer of major salivary glands neoplasms Both 0.01585 1.15 1.03,1.29 310 3093 0.00537 1.18 1.05,1.32 297 3031
145.4 Cancer of the gums neoplasms Both 0.8299 0.982 0.828,1.16 143 1419 0.7762 0.975 0.822,1.16 141 1391
145.5 Cancer of the mouth floor neoplasms Both 0.826 0.983 0.842,1.15 173 1723 0.7638 0.976 0.834,1.14 167 1701
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.8954 0.996 0.937,1.06 1124 11202 0.8091 1.02 0.881,1.18 204 2026
149.1 Cancer of oropharynx neoplasms Both 0.7621 0.981 0.868,1.11 291 2892 0.787 0.983 0.869,1.11 288 2844
149.2 Cancer of nasopharynx neoplasms Both 0.9078 1.01 0.814,1.26 87 855 0.9057 1.01 0.813,1.26 86 844
149.3 Cancer of hypopharynx neoplasms Both 0.5916 1.07 0.834,1.38 68 680 0.5649 1.08 0.837,1.39 68 673
149.4 Cancer of larynx neoplasms Both 0.6237 1.03 0.921,1.15 332 3314 0.6124 1.03 0.921,1.15 326 3248
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.6427 1.02 0.933,1.12 505 5041 0.6998 1.02 0.929,1.12 493 4956
149.9 Cancer of of nasal cavities neoplasms Both 0.9099 1.01 0.873,1.16 208 2067 0.8091 1.02 0.881,1.18 204 2026
150 Cancer of esophagus neoplasms Both 0.06918 0.906 0.815,1.01 378 3776 0.07762 0.908 0.816,1.01 377 3714
151 Cancer of stomach neoplasms Both 0.0955 0.919 0.832,1.02 430 4292 0.06026 0.908 0.821,1.0 423 4222
153 Colorectal cancer neoplasms Both 0.1738 1.04 0.982,1.11 1196 11882 0.4036 1.03 0.956,1.12 654 6563
153.2 Colon cancer neoplasms Both 0.7674 1.01 0.945,1.08 941 9327 0.9183 1.0 0.938,1.07 918 9193
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.2931 1.04 0.964,1.13 669 6663 0.4036 1.03 0.956,1.12 654 6563
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.2432 0.942 0.852,1.04 418 4180 0.2655 0.932 0.824,1.05 279 2795
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.413 0.95 0.841,1.07 285 2850 0.2655 0.932 0.824,1.05 279 2795
157 Pancreatic cancer neoplasms Both 0.06457 0.911 0.825,1.01 430 4292 0.04467 0.902 0.816,0.997 421 4219
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.3184 0.972 0.919,1.03 1369 13455 0.2553 0.968 0.914,1.02 1329 13244
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.0955 0.939 0.872,1.01 779 7785 0.02344 0.857 0.749,0.979 245 2526
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.8279 1.02 0.874,1.18 183 1830 0.7852 1.02 0.877,1.19 179 1802
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.04169 0.832 0.698,0.993 133 1330 0.02951 0.821 0.687,0.98 132 1317
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.03311 0.867 0.76,0.989 255 2550 0.02344 0.857 0.749,0.979 245 2526
164 Cancer of intrathoracic organs neoplasms Both 0.8299 0.979 0.809,1.19 111 1110 0.9594 1.01 0.829,1.22 109 1089
165 Cancer within the respiratory system neoplasms Both 0.5754 0.981 0.918,1.05 945 9436 0.9036 0.996 0.928,1.07 847 8558
165.1 Cancer of bronchus; lung neoplasms Both 0.7798 0.99 0.924,1.06 874 8724 0.9036 0.996 0.928,1.07 847 8558
170 Cancer of bone and connective tissue neoplasms Both 0.9886 1.0 0.949,1.05 1538 15304 0.3673 0.971 0.912,1.03 1064 10768
170.1 Bone cancer neoplasms Both 0.5943 1.02 0.944,1.11 668 6660 0.8072 1.01 0.931,1.1 631 6559
170.2 Cancer of connective tissue neoplasms Both 0.526 0.98 0.921,1.04 1097 10941 0.3673 0.971 0.912,1.03 1064 10768
172 Skin cancer neoplasms Both 6.31E-11 1.09 1.07,1.12 7099 27878 8.913E-5 1.13 1.06,1.2 1153 10111
172.1 Melanomas of skin, dx or hx neoplasms Both 2.512E-8 1.12 1.08,1.17 2701 21867 5.754E-8 1.12 1.08,1.17 2551 21243
172.11 Melanomas of skin neoplasms Both 2.512E-8 1.12 1.08,1.17 2624 21526 5.754E-8 1.12 1.08,1.17 2551 21243
172.2 Other non-epithelial cancer of skin neoplasms Both 3.162E-11 1.1 1.07,1.14 5888 25669 3.02E-6 1.12 1.07,1.18 1844 14377
172.21 Basal cell carcinoma neoplasms Both 5.012E-11 1.14 1.1,1.18 2988 20068 4.365E-10 1.13 1.09,1.18 2900 19806
172.22 Squamous cell carcinoma neoplasms Both 6.761E-7 1.13 1.08,1.19 1917 14585 3.02E-6 1.12 1.07,1.18 1844 14377
172.3 Carcinoma in situ of skin neoplasms Both 2.188E-5 1.14 1.07,1.21 1215 10290 8.913E-5 1.13 1.06,1.2 1153 10111
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.004169 1.08 1.02,1.14 1575 15093 0.005888 1.08 1.02,1.14 1531 14885
174 Breast cancer neoplasms Both 0.4487 0.984 0.943,1.03 2694 13131 0.9795 1.0 0.866,1.16 202 2032
174.1 Breast cancer [female] neoplasms Female 0.5929 0.988 0.946,1.03 2605 12548 0.6252 0.989 0.947,1.03 2533 12387
174.11 Malignant neoplasm of female breast neoplasms Female 0.6397 0.99 0.948,1.03 2565 12510 0.6252 0.989 0.947,1.03 2533 12387
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.8337 1.02 0.879,1.17 206 2051 0.9795 1.0 0.866,1.16 202 2032
175 Acquired absence of breast neoplasms Female 0.7516 1.01 0.945,1.08 978 9172 0.7691 1.01 0.944,1.08 967 9078
180 Cervical cancer and dysplasia neoplasms Female 0.7798 1.01 0.949,1.07 1182 10494 0.3319 1.04 0.964,1.11 837 7832
180.1 Cervical cancer neoplasms Female 0.8072 0.988 0.893,1.09 430 4300 0.7834 0.986 0.891,1.09 422 4263
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.3963 1.03 0.96,1.11 857 7886 0.3319 1.04 0.964,1.11 837 7832
182 Malignant neoplasm of uterus neoplasms Female 0.4742 0.971 0.895,1.05 643 6390 0.415 0.966 0.89,1.05 633 6305
184 Cancer of other female genital organs neoplasms Female 0.3296 1.03 0.966,1.11 910 8957 0.3148 1.05 0.957,1.15 519 5196
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.6252 1.02 0.932,1.12 491 4888 0.3899 1.05 0.941,1.17 360 3613
184.11 Malignant neoplasm of ovary neoplasms Female 0.3133 1.06 0.949,1.18 367 3659 0.3899 1.05 0.941,1.17 360 3613
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.3027 1.05 0.958,1.15 526 5253 0.3148 1.05 0.957,1.15 519 5196
185 Cancer of prostate neoplasms Male 0.02754 0.949 0.905,0.994 2432 8825 0.01862 0.945 0.901,0.991 2384 8689
187 Cancer of other male genital organs neoplasms Male 0.7228 1.02 0.902,1.16 276 2723 0.6792 1.04 0.872,1.23 139 1367
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.7586 1.03 0.84,1.27 96 960 0.6871 1.04 0.847,1.29 92 937
187.2 Malignant neoplasm of testis neoplasms Male 0.631 1.04 0.879,1.24 144 1387 0.6792 1.04 0.872,1.23 139 1367
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.2037 0.974 0.934,1.01 2552 20553 0.03548 0.912 0.837,0.994 584 5709
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.375 0.974 0.92,1.03 1261 12588 0.07079 0.873 0.753,1.01 194 1960
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.5012 0.979 0.92,1.04 1083 10823 0.471 0.977 0.917,1.04 1044 10619
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.1239 0.893 0.773,1.03 202 2010 0.07079 0.873 0.753,1.01 194 1960
189.2 Cancer of bladder neoplasms Both 0.16 0.963 0.914,1.02 1575 13516 0.06026 0.948 0.897,1.0 1422 12307
189.21 Malignant neoplasm of bladder neoplasms Both 0.06918 0.951 0.9,1.0 1456 12558 0.06026 0.948 0.897,1.0 1422 12307
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.08318 0.928 0.853,1.01 601 5841 0.03548 0.912 0.837,0.994 584 5709
190 Cancer of eye neoplasms Both 0.007586 1.29 1.07,1.56 114 1125 0.005888 1.31 1.08,1.58 110 1102
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.1535 1.05 0.982,1.12 904 9040 0.06761 1.09 0.994,1.2 471 4773
191.1 Cancer of brain and nervous system neoplasms Both 0.2075 1.06 0.97,1.15 580 5800 0.06761 1.09 0.994,1.2 471 4773
191.11 Cancer of brain neoplasms Both 0.05495 1.09 0.998,1.2 483 4830 0.06761 1.09 0.994,1.2 471 4773
193 Thyroid cancer neoplasms Both 0.08318 0.937 0.872,1.01 798 7953 0.08913 0.938 0.871,1.01 777 7849
194 Cancer of other endocrine glands neoplasms Both 0.2133 0.916 0.798,1.05 221 2207 0.2761 0.925 0.805,1.06 216 2173
195 Cancer, suspected or other neoplasms Both 0.8933 0.998 0.975,1.02 12134 23141 0.7464 1.01 0.945,1.08 942 8921
195.1 Malignant neoplasm, other neoplasms Both 0.9354 0.999 0.976,1.02 11693 23098 0.7194 0.996 0.972,1.02 11294 23012
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.5768 1.02 0.954,1.09 970 8963 0.7464 1.01 0.945,1.08 942 8921
196 Radiotherapy neoplasms Both 0.9204 0.998 0.952,1.05 2067 15612 0.5715 0.986 0.941,1.03 2006 15543
197 Chemotherapy neoplasms Both 0.2399 0.98 0.946,1.01 4051 21210 0.2056 0.977 0.943,1.01 3775 21126
198 Secondary malignant neoplasm neoplasms Both 0.169 0.978 0.947,1.01 4986 21474 0.4603 1.05 0.925,1.19 275 2738
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.2944 0.98 0.943,1.02 3156 19844 0.2938 0.98 0.943,1.02 3087 19763
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.9419 0.997 0.931,1.07 903 8847 0.8128 0.992 0.925,1.06 877 8804
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.0309 0.918 0.849,0.992 725 7166 0.01778 0.909 0.84,0.984 707 7126
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.4325 0.968 0.892,1.05 643 6395 0.3296 0.959 0.883,1.04 623 6369
198.5 Secondary malignancy of brain/spine neoplasms Both 0.7816 1.01 0.927,1.11 545 5421 0.787 1.01 0.926,1.11 528 5390
198.6 Secondary malignancy of bone neoplasms Both 0.5433 1.02 0.948,1.11 712 6962 0.743 1.01 0.936,1.1 670 6927
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.3296 1.06 0.94,1.2 287 2752 0.4603 1.05 0.925,1.19 275 2738
199 Neoplasm of uncertain behavior neoplasms Both 0.07244 0.971 0.941,1.0 4947 22823 0.07943 1.24 0.976,1.57 71 716
199.4 Neurofibromatosis neoplasms Both 0.05888 1.26 0.991,1.59 72 720 0.07943 1.24 0.976,1.57 71 716
200 Myeloproliferative disease neoplasms Both 0.3784 0.969 0.904,1.04 886 8851 0.06166 0.845 0.708,1.01 143 1610
200.1 Polycythemia vera neoplasms Both 0.1355 0.881 0.746,1.04 161 1610 0.06166 0.845 0.708,1.01 143 1610
201 Hodgkin's disease neoplasms Both 0.1919 0.891 0.749,1.06 138 1373 0.4315 0.929 0.772,1.12 119 1373
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.9247 0.997 0.942,1.06 1308 13070 0.9594 0.995 0.817,1.21 109 1300
202.2 Non-Hodgkins lymphoma neoplasms Both 0.7925 1.01 0.949,1.07 1141 11402 0.9594 0.995 0.817,1.21 109 1300
202.21 Nodular lymphoma neoplasms Both 0.9772 0.999 0.92,1.08 632 6320 0.7228 0.985 0.905,1.07 583 6320
202.22 Reticulosarcoma neoplasms Both 0.6109 0.956 0.802,1.14 137 1355 0.8551 0.983 0.814,1.19 116 1355
202.24 Large cell lymphoma neoplasms Both 0.5035 0.94 0.784,1.13 132 1300 0.9594 0.995 0.817,1.21 109 1300
204 Leukemia neoplasms Both 0.134 1.07 0.979,1.17 545 5450 ,
204.1 Lymphoid leukemia neoplasms Both 0.01318 1.21 1.04,1.41 187 1870 ,
204.11 Lymphoid leukemia, acute neoplasms Both 0.7638 1.04 0.804,1.34 58 580 ,
204.12 Lymphoid leukemia, chronic neoplasms Both 0.0123 1.24 1.05,1.48 136 1350 ,
204.2 Myeloid leukemia neoplasms Both 0.1866 1.1 0.953,1.28 206 2060 ,
204.21 Myeloid leukemia, acute neoplasms Both 0.1076 1.17 0.966,1.42 124 1240 ,
204.4 Multiple myeloma neoplasms Both 0.7638 1.02 0.877,1.2 180 1795 ,
208 Benign neoplasm of colon neoplasms Both 0.9528 0.999 0.974,1.02 8098 29324 0.8433 0.997 0.972,1.02 7915 28973
209 Neuroendocrine tumors neoplasms Both 0.2523 0.923 0.805,1.06 222 2220 0.2564 0.923 0.803,1.06 216 2181
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.8851 1.0 0.953,1.06 1584 15798 0.8492 1.01 0.954,1.06 1551 15562
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.6902 0.994 0.967,1.02 5807 30296 0.5321 0.991 0.963,1.02 5655 29948
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.0302 1.06 1.01,1.12 1556 15533 0.02455 1.06 1.01,1.12 1495 15324
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.3776 0.975 0.923,1.03 1405 13304 0.4775 0.98 0.927,1.04 1372 13195
214 Lipoma neoplasms Both 0.7621 0.991 0.931,1.05 1117 11124 0.7762 0.988 0.913,1.07 668 6700
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.6026 0.979 0.905,1.06 681 6793 0.7762 0.988 0.913,1.07 668 6700
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.8851 0.997 0.963,1.03 3594 32904 0.9772 0.999 0.965,1.04 3507 32475
216 Benign neoplasm of skin neoplasms Both 0.3873 1.01 0.987,1.03 9073 29036 0.1416 0.86 0.704,1.05 108 1079
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.1995 0.879 0.722,1.07 111 1093 0.1416 0.86 0.704,1.05 108 1079
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.2118 1.04 0.978,1.1 1150 11417 0.3436 1.03 0.968,1.1 1039 10424
217.1 Nevus, non-neoplastic neoplasms Both 0.2523 1.04 0.974,1.1 1063 10579 0.3436 1.03 0.968,1.1 1039 10424
218 Benign neoplasm of uterus neoplasms Female 0.4624 0.986 0.95,1.02 3552 13845 0.7178 0.992 0.952,1.03 2786 13566
218.1 Uterine leiomyoma neoplasms Female 0.2004 0.965 0.915,1.02 1506 13465 0.2371 0.968 0.917,1.02 1488 13338
218.2 Other benign neoplasm of uterus neoplasms Female 0.7464 0.993 0.954,1.03 2824 13698 0.7178 0.992 0.952,1.03 2786 13566
220 Benign neoplasm of ovary neoplasms Female 0.6823 0.984 0.912,1.06 763 7571 0.6761 0.984 0.911,1.06 755 7504
221 Benign neoplasm of other female genital organs neoplasms Female 0.8166 0.994 0.944,1.05 1666 12074 0.7621 0.992 0.942,1.04 1649 11962
222 Benign neoplasm of male genital organs neoplasms Male 0.2188 0.959 0.897,1.03 954 9116 0.3177 0.966 0.903,1.03 929 8917
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.1633 0.962 0.912,1.02 1547 11080 0.2667 0.97 0.918,1.02 1495 10975
224 Benign neoplasm of eye neoplasms Both 0.4436 0.965 0.882,1.06 511 5062 0.5058 0.966 0.873,1.07 418 4146
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.6138 0.975 0.882,1.08 429 4230 0.5058 0.966 0.873,1.07 418 4146
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.5105 0.979 0.918,1.04 1039 10379 0.5534 0.96 0.837,1.1 228 2381
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.873 0.994 0.925,1.07 817 8160 0.8933 0.995 0.925,1.07 802 8052
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.5808 0.963 0.843,1.1 242 2420 0.5534 0.96 0.837,1.1 228 2381
226 Benign neoplasm of thyroid glands neoplasms Both 0.3656 0.971 0.912,1.03 1082 10810 0.3954 0.973 0.913,1.04 1063 10653
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.4613 1.02 0.966,1.08 1387 13870 0.5508 1.03 0.93,1.15 368 3669
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.8054 1.01 0.912,1.13 375 3745 0.7345 1.02 0.916,1.13 368 3698
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.2477 1.05 0.967,1.14 644 6434 0.208 1.05 0.971,1.14 638 6354
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.5508 1.03 0.93,1.14 373 3724 0.5508 1.03 0.93,1.15 368 3669
228 Hemangioma and lymphangioma, any site neoplasms Both 0.7943 1.01 0.955,1.06 1517 15150 0.1901 1.05 0.977,1.13 826 8350
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.1148 1.06 0.986,1.14 849 8478 0.1901 1.05 0.977,1.13 826 8350
229 Benign neoplasm of unspecified sites neoplasms Both 0.03548 1.03 1.0,1.06 6631 31223 0.07244 1.03 0.997,1.06 4822 29294
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.08128 1.03 0.997,1.06 4904 29712 0.07244 1.03 0.997,1.06 4822 29294
860 Bone marrow or stem cell transplant neoplasms Both 0.4831 1.07 0.888,1.29 127 1266 0.6761 1.06 0.803,1.4 51 1247
240 Simple and unspecified goiter endocrine/metabolic Both 0.8241 1.01 0.936,1.09 767 7647 0.8147 1.01 0.936,1.09 747 7540
241 Nontoxic nodular goiter endocrine/metabolic Both 0.3041 0.977 0.935,1.02 2274 18240 0.7798 0.991 0.929,1.06 1001 9940
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.3199 0.975 0.929,1.02 1795 16440 0.2735 0.973 0.926,1.02 1760 16233
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.8453 0.994 0.932,1.06 1017 10065 0.7798 0.991 0.929,1.06 1001 9940
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.1734 1.04 0.981,1.11 1075 10635 0.6124 1.05 0.867,1.27 113 1148
242.1 Graves' disease endocrine/metabolic Both 0.2042 1.07 0.965,1.18 399 3965 0.2259 1.07 0.962,1.18 392 3918
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.7798 0.971 0.788,1.2 98 978 0.811 0.975 0.791,1.2 97 964
242.3 Exophthalmos endocrine/metabolic Both 0.4688 1.05 0.921,1.2 245 2447 0.6124 1.05 0.867,1.27 113 1148
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.5093 1.07 0.882,1.29 116 1160 0.6124 1.05 0.867,1.27 113 1148
244 Hypothyroidism endocrine/metabolic Both 0.3724 1.01 0.985,1.04 6448 27183 0.2432 1.02 0.988,1.05 5866 26359
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.5998 0.986 0.933,1.04 1421 14153 0.5675 0.984 0.932,1.04 1389 13973
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.7745 1.01 0.942,1.08 853 8502 0.7178 1.01 0.944,1.09 818 8379
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.2773 1.02 0.987,1.05 5996 26719 0.2432 1.02 0.988,1.05 5866 26359
245 Thyroiditis endocrine/metabolic Both 0.02344 1.1 1.01,1.2 574 5720 0.08318 1.09 0.989,1.2 447 4499
245.2 Chronic thyroiditis endocrine/metabolic Both 0.08913 1.09 0.988,1.19 463 4617 0.08318 1.09 0.989,1.2 447 4499
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.1021 1.08 0.984,1.19 456 4533 0.08318 1.09 0.989,1.2 447 4499
246 Other disorders of thyroid endocrine/metabolic Both 0.537 1.01 0.979,1.04 5018 25158 0.526 0.972 0.891,1.06 556 5575
246.2 Thyroid cyst endocrine/metabolic Both 0.7047 1.04 0.836,1.3 83 804 0.7047 1.04 0.835,1.31 82 789
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.5998 0.977 0.896,1.07 568 5651 0.526 0.972 0.891,1.06 556 5575
249 Secondary diabetes mellitus endocrine/metabolic Both 0.1496 1.06 0.98,1.14 686 6849 0.1432 1.06 0.98,1.15 656 6752
250 Diabetes mellitus endocrine/metabolic Both 0.787 0.997 0.974,1.02 10115 27568 0.3228 1.04 0.964,1.12 793 8035
250.1 Type 1 diabetes endocrine/metabolic Both 0.3311 1.03 0.969,1.1 1053 10521 0.03311 1.3 1.02,1.66 67 685
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.00537 1.36 1.1,1.69 80 792 0.008128 1.35 1.08,1.69 74 787
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.001259 1.24 1.09,1.41 235 2346 9.772E-4 1.25 1.1,1.44 219 2314
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.004467 1.19 1.06,1.34 280 2800 0.003236 1.2 1.06,1.35 268 2771
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.01202 1.18 1.04,1.34 238 2372 0.01479 1.18 1.03,1.35 222 2341
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.03548 1.29 1.02,1.64 70 690 0.03311 1.3 1.02,1.66 67 685
250.2 Type 2 diabetes endocrine/metabolic Both 0.9977 1.0 0.973,1.03 7035 26169 0.3451 1.05 0.953,1.15 488 4980
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.1795 1.14 0.943,1.37 120 1200 0.1982 1.14 0.936,1.38 112 1187
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.1722 0.958 0.901,1.02 1133 11056 0.2213 0.962 0.904,1.02 1093 10873
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.8933 1.0 0.935,1.08 826 8208 0.8492 1.01 0.936,1.08 798 8078
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.7015 0.989 0.937,1.05 1419 13969 0.7586 0.991 0.938,1.05 1368 13755
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.4207 1.04 0.948,1.14 513 5077 0.3451 1.05 0.953,1.15 488 4980
250.3 Insulin pump user endocrine/metabolic Both 0.9727 1.0 0.954,1.05 1884 17814 0.871 1.0 0.957,1.05 1825 17570
250.4 Abnormal glucose endocrine/metabolic Both 0.929 0.999 0.969,1.03 5404 26451 0.9078 0.998 0.967,1.03 4603 25585
250.41 Impaired fasting glucose endocrine/metabolic Both 0.1941 1.04 0.981,1.1 1326 13130 0.1932 1.04 0.981,1.1 1298 12939
250.42 Other abnormal glucose endocrine/metabolic Both 0.9572 0.999 0.968,1.03 4736 25883 0.9078 0.998 0.967,1.03 4603 25585
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.877 0.982 0.778,1.24 78 747 0.8147 0.972 0.769,1.23 77 743
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.695 1.01 0.952,1.08 1137 11335 0.7063 1.01 0.951,1.08 1096 11160
250.7 Diabetic retinopathy endocrine/metabolic Both 0.3443 1.04 0.963,1.11 821 8168 0.3228 1.04 0.964,1.12 793 8035
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.1213 1.07 0.983,1.16 595 5901 0.1514 1.06 0.979,1.15 675 6935
251.1 Hypoglycemia endocrine/metabolic Both 0.15 1.06 0.98,1.14 702 7015 0.1514 1.06 0.979,1.15 675 6935
252 Disorders of parathyroid gland endocrine/metabolic Both 0.5333 0.985 0.938,1.03 1807 17879 0.2317 0.938 0.844,1.04 381 3882
252.1 Hyperparathyroidism endocrine/metabolic Both 0.975 1.0 0.951,1.05 1656 16459 0.9419 1.0 0.952,1.05 1616 16253
252.2 Hypoparathyroidism endocrine/metabolic Both 0.2009 0.935 0.842,1.04 393 3922 0.2317 0.938 0.844,1.04 381 3882
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.2133 0.951 0.879,1.03 691 6893 0.673 0.953 0.763,1.19 88 914
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.1094 0.886 0.765,1.03 205 2041 0.07762 0.803 0.629,1.02 72 712
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.07586 0.802 0.629,1.02 72 720 0.07762 0.803 0.629,1.02 72 712
253.2 Pituitary hypofunction endocrine/metabolic Both 0.7228 1.03 0.886,1.19 184 1840 0.537 1.05 0.902,1.22 178 1818
253.3 Diabetes insipidus endocrine/metabolic Both 0.8128 1.03 0.813,1.3 70 694 0.8472 1.02 0.806,1.3 67 686
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.5861 0.942 0.76,1.17 92 899 0.7244 0.962 0.774,1.2 89 887
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.6067 0.945 0.761,1.17 93 925 0.673 0.953 0.763,1.19 88 914
255 Disorders of adrenal glands endocrine/metabolic Both 0.8414 1.01 0.948,1.07 1186 11860 0.4966 1.03 0.938,1.14 428 4439
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.9376 1.0 0.891,1.13 290 2886 0.873 0.983 0.803,1.21 104 1041
255.11 Cushing's syndrome endocrine/metabolic Both 0.4246 1.07 0.904,1.27 144 1440 0.5023 1.06 0.892,1.26 140 1428
255.12 Hyperaldosteronism endocrine/metabolic Both 0.7889 0.973 0.795,1.19 106 1057 0.873 0.983 0.803,1.21 104 1041
255.2 Adrenal hypofunction endocrine/metabolic Both 0.7745 1.01 0.923,1.11 477 4758 0.4966 1.03 0.938,1.14 428 4439
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.7516 1.02 0.922,1.12 451 4496 0.4966 1.03 0.938,1.14 428 4439
256 Ovarian dysfunction endocrine/metabolic Female 0.4732 1.03 0.956,1.1 859 8184 0.9795 1.0 0.916,1.09 538 5400
256.4 Polycystic ovaries endocrine/metabolic Female 0.9616 1.0 0.917,1.1 544 5436 0.9795 1.0 0.916,1.09 538 5400
257 Testicular dysfunction endocrine/metabolic Male 0.6166 0.981 0.91,1.06 747 7455 0.7328 0.987 0.913,1.07 699 7095
257.1 Testicular hypofunction endocrine/metabolic Male 0.5445 0.977 0.905,1.05 725 7234 0.7328 0.987 0.913,1.07 699 7095
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.3846 1.11 0.873,1.42 66 660 0.04571 0.791 0.629,0.995 84 912
258.1 Postablative ovarian failure endocrine/metabolic Female 0.02754 0.781 0.626,0.973 92 920 0.04571 0.791 0.629,0.995 84 912
259 Other endocrine disorders endocrine/metabolic Both 0.4121 0.969 0.899,1.04 759 7562 0.5023 0.974 0.903,1.05 743 7489
260 Protein-calorie malnutrition endocrine/metabolic Both 0.3999 0.982 0.941,1.02 2353 22279 0.4797 0.971 0.894,1.05 628 6643
260.1 Cachexia endocrine/metabolic Both 0.4385 0.949 0.83,1.08 239 2388 0.4276 0.945 0.823,1.09 218 2354
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.4667 0.979 0.926,1.04 1363 13589 0.929 0.995 0.896,1.11 384 4079
260.22 Nutritional marasmus endocrine/metabolic Both 0.798 1.01 0.916,1.12 413 4130 0.929 0.995 0.896,1.11 384 4079
260.3 Adult failure to thrive endocrine/metabolic Both 0.1368 1.07 0.979,1.17 509 5051 0.3133 1.05 0.956,1.15 474 4986
260.6 Anorexia endocrine/metabolic Both 0.3606 0.964 0.89,1.04 677 6722 0.4797 0.971 0.894,1.05 628 6643
261 Vitamin deficiency endocrine/metabolic Both 0.4159 0.988 0.96,1.02 5614 30157 0.4416 0.988 0.959,1.02 5126 29552
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.8551 1.01 0.929,1.09 649 6482 0.9616 1.0 0.923,1.09 620 6399
261.4 Vitamin D deficiency endocrine/metabolic Both 0.4093 0.988 0.959,1.02 5264 29859 0.4416 0.988 0.959,1.02 5126 29552
262 Mineral deficiency NEC endocrine/metabolic Both 0.1888 0.954 0.889,1.02 854 8532 0.1256 0.945 0.879,1.02 823 8445
263 Other nutritional deficiency endocrine/metabolic Both 0.4295 0.96 0.868,1.06 412 4113 0.3882 0.956 0.863,1.06 394 4072
264 Lack of normal physiological development endocrine/metabolic Both 0.0631 1.16 0.992,1.35 175 1735 0.8318 1.03 0.793,1.33 58 604
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.1742 1.15 0.939,1.42 95 950 0.1294 1.18 0.952,1.47 86 939
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.7907 1.04 0.803,1.33 61 607 0.8318 1.03 0.793,1.33 58 604
269 Proteinuria endocrine/metabolic Both 0.8299 1.01 0.946,1.07 1079 10768 0.8222 1.01 0.945,1.07 1018 10630
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.9661 0.998 0.925,1.08 740 7378 0.8128 1.02 0.879,1.18 193 2150
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.07244 0.842 0.698,1.02 129 1283 0.07586 0.824 0.667,1.02 100 985
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.05888 0.815 0.659,1.01 101 998 0.07586 0.824 0.667,1.02 100 985
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.1866 0.85 0.668,1.08 81 810 0.1702 0.84 0.655,1.08 76 793
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.4842 1.03 0.946,1.13 560 5581 0.8128 1.02 0.879,1.18 193 2150
270.32 Paraproteinemia endocrine/metabolic Both 0.8511 0.989 0.878,1.11 301 2982 0.4487 0.95 0.831,1.09 236 2931
270.33 Amyloidosis endocrine/metabolic Both 0.271 1.17 0.886,1.54 55 550 ,
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.5058 1.05 0.912,1.2 218 2178 0.8128 1.02 0.879,1.18 193 2150
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.9462 1.0 0.956,1.05 1952 19491 0.6531 1.05 0.841,1.32 80 799
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.9397 1.0 0.955,1.05 1885 18823 0.9311 0.998 0.951,1.05 1853 18536
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.6081 1.06 0.848,1.32 81 810 0.6531 1.05 0.841,1.32 80 799
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.6808 1.0 0.982,1.03 14793 22696 0.507 0.956 0.837,1.09 236 2393
272.1 Hyperlipidemia endocrine/metabolic Both 0.7228 1.0 0.982,1.03 14763 22682 0.6109 0.988 0.945,1.03 2214 15294
272.11 Hypercholesterolemia endocrine/metabolic Both 0.3184 1.02 0.984,1.05 4668 18640 0.3936 1.01 0.981,1.05 4557 18423
272.12 Hyperglyceridemia endocrine/metabolic Both 0.743 1.01 0.946,1.08 945 9395 0.8318 1.01 0.942,1.08 919 9266
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.5188 0.985 0.943,1.03 2272 15492 0.6109 0.988 0.945,1.03 2214 15294
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.3664 0.942 0.826,1.07 244 2425 0.507 0.956 0.837,1.09 236 2393
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.6546 1.01 0.965,1.06 1971 18337 0.8054 1.02 0.857,1.22 137 1340
274.1 Gout endocrine/metabolic Both 0.5598 1.01 0.967,1.06 1879 17712 0.3499 1.04 0.962,1.12 757 7757
274.11 Gouty arthropathy endocrine/metabolic Both 0.271 1.04 0.969,1.12 793 7891 0.3499 1.04 0.962,1.12 757 7757
274.2 Crystal arthropathies endocrine/metabolic Both 0.7482 1.03 0.867,1.22 146 1425 0.8054 1.02 0.857,1.22 137 1340
274.21 Chondrocalcinosis endocrine/metabolic Both 0.5821 1.05 0.882,1.25 140 1363 0.8054 1.02 0.857,1.22 137 1340
275 Disorders of mineral metabolism endocrine/metabolic Both 0.8492 1.0 0.968,1.04 3252 30253 0.3681 0.885 0.679,1.15 64 694
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.8318 1.01 0.938,1.08 845 8441 0.8279 1.01 0.936,1.09 767 8338
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.9441 1.0 0.961,1.04 2502 24757 0.7413 0.989 0.926,1.06 955 10066
275.51 Hypocalcemia endocrine/metabolic Both 0.7379 0.987 0.914,1.07 722 7203 0.5023 0.973 0.899,1.05 684 7129
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.9247 1.0 0.941,1.07 1024 10193 0.7413 0.989 0.926,1.06 955 10066
275.6 Hypercalcemia endocrine/metabolic Both 0.0912 1.06 0.991,1.13 1043 10415 0.1256 1.05 0.986,1.12 995 10293
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.6152 1.01 0.981,1.03 7227 30901 0.3048 1.11 0.91,1.35 96 981
276.1 Electrolyte imbalance endocrine/metabolic Both 0.2328 0.981 0.951,1.01 4833 28673 0.7603 0.992 0.941,1.05 1525 16000
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.8185 1.01 0.915,1.12 415 4115 0.8913 0.993 0.896,1.1 398 4065
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.9462 1.0 0.955,1.05 1857 17982 0.9162 0.997 0.95,1.05 1776 17776
276.13 Hyperpotassemia endocrine/metabolic Both 0.3162 0.978 0.936,1.02 2238 20576 0.2203 0.972 0.93,1.02 2131 20336
276.14 Hypopotassemia endocrine/metabolic Both 0.9931 1.0 0.95,1.05 1626 16160 0.7603 0.992 0.941,1.05 1525 16000
276.4 Acid-base balance disorder endocrine/metabolic Both 0.3192 1.03 0.975,1.08 1593 15855 0.4009 0.953 0.851,1.07 333 3461
276.41 Acidosis endocrine/metabolic Both 0.1928 1.04 0.982,1.1 1357 13508 0.2286 1.04 0.978,1.1 1299 13351
276.42 Alkalosis endocrine/metabolic Both 0.3981 0.954 0.854,1.06 350 3498 0.4009 0.953 0.851,1.07 333 3461
276.5 Hypovolemia endocrine/metabolic Both 0.3963 1.02 0.98,1.05 3615 28901 0.3776 1.02 0.981,1.05 3457 28628
276.6 Fluid overload endocrine/metabolic Both 0.01698 1.08 1.01,1.15 1046 10404 0.01549 1.08 1.02,1.16 984 10261
276.8 Polydipsia endocrine/metabolic Both 0.3741 1.09 0.899,1.33 99 990 0.3048 1.11 0.91,1.35 96 981
277 Other disorders of metabolism endocrine/metabolic Both 0.1069 1.04 0.991,1.1 1534 15324 0.2985 1.05 0.961,1.14 591 6008
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.06918 1.13 0.991,1.28 252 2520 0.09333 1.12 0.981,1.28 231 2473
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.7261 0.984 0.902,1.07 547 5456 0.869 0.992 0.907,1.09 512 5375
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.5117 1.03 0.95,1.11 675 6743 0.4457 1.03 0.949,1.13 557 5573
277.51 Lipoprotein disorders endocrine/metabolic Both 0.3556 1.04 0.956,1.13 567 5665 0.4457 1.03 0.949,1.13 557 5573
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.3459 1.04 0.958,1.13 610 6090 0.2985 1.05 0.961,1.14 591 6008
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.1714 0.986 0.966,1.01 15130 23191 0.5957 0.986 0.934,1.04 1492 13524
278.1 Obesity endocrine/metabolic Both 0.2594 0.988 0.967,1.01 13507 23193 0.5834 0.992 0.965,1.02 6282 22835
278.11 Morbid obesity endocrine/metabolic Both 0.5284 0.991 0.964,1.02 6376 23143 0.5834 0.992 0.965,1.02 6282 22835
278.3 Localized adiposity endocrine/metabolic Both 0.03311 0.871 0.766,0.989 270 2694 0.04786 0.878 0.772,0.999 263 2661
278.4 Abnormal weight gain endocrine/metabolic Both 0.4842 0.981 0.93,1.03 1522 13685 0.5957 0.986 0.934,1.04 1492 13524
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.7798 1.01 0.963,1.05 2245 22393 0.6339 0.976 0.884,1.08 424 4390
279.1 Immunity deficiency endocrine/metabolic Both 0.8872 1.01 0.938,1.08 881 8792 0.4853 0.95 0.823,1.1 203 2515
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.5047 0.957 0.841,1.09 254 2540 0.4853 0.95 0.823,1.1 203 2515
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.7311 1.02 0.932,1.11 574 5735 0.955 0.998 0.915,1.09 553 5689
279.7 Other immunological findings endocrine/metabolic Both 0.5929 1.01 0.976,1.04 3927 30734 0.7603 1.01 0.971,1.04 3724 30463
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.7362 0.983 0.892,1.08 443 4423 0.6339 0.976 0.884,1.08 424 4390
275.1 Disorders of iron metabolism hematopoietic Both 0.5957 1.05 0.888,1.23 168 1680 0.3681 0.885 0.679,1.15 64 694
275.11 Hereditary hemochromatosis hematopoietic Both 0.317 0.877 0.679,1.13 70 700 0.3681 0.885 0.679,1.15 64 694
280 Iron deficiency anemias hematopoietic Both 0.1774 0.976 0.942,1.01 3537 25593 0.7161 1.01 0.954,1.07 1299 13404
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.1205 0.972 0.937,1.01 3410 25349 0.07586 0.967 0.932,1.0 3284 25154
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.4581 1.02 0.966,1.08 1361 13511 0.7161 1.01 0.954,1.07 1299 13404
281 Other deficiency anemia hematopoietic Both 0.7194 1.02 0.918,1.13 387 3838 0.9204 1.01 0.867,1.17 185 2092
281.1 Megaloblastic anemia hematopoietic Both 0.7834 0.979 0.844,1.14 189 1875 0.859 0.984 0.825,1.17 131 1339
281.11 Pernicious anemia hematopoietic Both 0.9594 1.01 0.811,1.25 84 830 0.9311 1.01 0.811,1.26 81 823
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.7161 0.968 0.813,1.15 135 1348 0.859 0.984 0.825,1.17 131 1339
281.9 Deficiency anemias hematopoietic Both 0.865 1.01 0.88,1.16 214 2110 0.9204 1.01 0.867,1.17 185 2092
282 Hereditary hemolytic anemias hematopoietic Both 0.6668 0.971 0.849,1.11 248 2443 0.2742 0.902 0.749,1.09 132 1403
282.8 Other hemoglobinopathies hematopoietic Both 0.228 0.901 0.761,1.07 158 1541 0.2328 0.9 0.758,1.07 151 1526
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.1256 0.868 0.725,1.04 143 1420 0.2742 0.902 0.749,1.09 132 1403
283 Acquired hemolytic anemias hematopoietic Both 0.1178 1.16 0.963,1.4 130 1295 0.1084 1.18 0.964,1.45 109 1277
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.1159 1.26 0.944,1.68 54 532 ,
284 Aplastic anemia hematopoietic Both 0.8974 1.01 0.921,1.1 558 5545 0.2716 0.942 0.846,1.05 366 4803
284.1 Pancytopenia hematopoietic Both 0.3524 0.957 0.871,1.05 488 4847 0.2716 0.942 0.846,1.05 366 4803
285 Other anemias hematopoietic Both 0.9247 0.999 0.975,1.02 9426 28014 0.9354 0.996 0.906,1.09 470 5489
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.1146 1.03 0.992,1.08 2536 22457 0.1875 1.03 0.986,1.07 2446 22270
285.2 Anemia of chronic disease hematopoietic Both 0.9931 1.0 0.95,1.05 1584 15823 0.9354 0.996 0.906,1.09 470 5489
285.21 Anemia in chronic kidney disease hematopoietic Both 0.6637 1.02 0.941,1.1 673 6722 0.6339 1.02 0.941,1.11 631 6651
285.22 Anemia in neoplastic disease hematopoietic Both 0.9376 1.0 0.919,1.1 555 5536 0.9354 0.996 0.906,1.09 470 5489
286 Coagulation defects hematopoietic Both 0.8453 0.996 0.959,1.03 3013 27144 0.6442 1.02 0.947,1.09 843 8661
286.1 Congenital coagulation defects hematopoietic Both 0.1738 0.9 0.774,1.05 190 1889 0.414 0.915 0.74,1.13 94 966
286.11 Von willebrand's disease hematopoietic Both 0.8995 1.02 0.788,1.31 64 640 0.8551 1.02 0.792,1.32 63 630
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.4477 0.922 0.748,1.14 98 973 0.414 0.915 0.74,1.13 94 966
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.1959 1.03 0.986,1.07 2601 20964 0.3365 1.02 0.979,1.06 2504 20752
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.7129 1.05 0.8,1.39 60 590 0.6902 1.06 0.801,1.4 58 589
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.1592 0.899 0.775,1.04 186 1860 0.1038 0.881 0.756,1.03 175 1840
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.1 1.18 0.969,1.44 92 906 0.1941 1.15 0.933,1.41 87 898
286.6 Defibrination syndrome hematopoietic Both 0.4581 0.983 0.938,1.03 1964 19522 0.3041 0.975 0.93,1.02 1874 19329
286.7 Other and unspecified coagulation defects hematopoietic Both 0.6871 0.991 0.95,1.03 2349 23153 0.4266 0.982 0.941,1.03 2244 22930
286.8 Hypercoagulable state hematopoietic Both 0.8318 1.01 0.93,1.09 643 6420 0.8375 0.991 0.912,1.08 597 6115
286.81 Primary hypercoagulable state hematopoietic Both 0.6934 1.02 0.936,1.1 618 6179 0.8375 0.991 0.912,1.08 597 6115
286.9 Abnormal coagulation profile hematopoietic Both 0.3133 1.04 0.967,1.11 890 8770 0.6442 1.02 0.947,1.09 843 8661
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.2523 1.02 0.983,1.07 2575 22699 0.8241 1.03 0.807,1.31 71 751
287.1 Spontaneous ecchymoses hematopoietic Both 0.5848 1.05 0.889,1.23 154 1532 0.6577 1.04 0.878,1.23 143 1514
287.3 Thrombocytopenia hematopoietic Both 0.3508 1.02 0.978,1.07 2297 20909 0.7727 0.985 0.886,1.09 388 4312
287.31 Primary thrombocytopenia hematopoietic Both 0.9204 1.0 0.914,1.1 481 4785 0.9462 0.997 0.903,1.1 441 4729
287.32 Secondary thrombocytopenia hematopoietic Both 0.6776 0.979 0.886,1.08 436 4360 0.7727 0.985 0.886,1.09 388 4312
287.4 Qualitative platelet defects hematopoietic Both 0.5508 1.07 0.85,1.36 76 760 0.8241 1.03 0.807,1.31 71 751
288 Diseases of white blood cells hematopoietic Both 0.389 0.985 0.953,1.02 3850 30383 0.005248 1.3 1.08,1.56 123 1267
288.1 Decreased white blood cell count hematopoietic Both 0.3776 0.974 0.919,1.03 1252 12520 0.5333 0.976 0.906,1.05 768 8886
288.11 Neutropenia hematopoietic Both 0.5035 0.976 0.911,1.05 896 8960 0.5333 0.976 0.906,1.05 768 8886
288.2 Elevated white blood cell count hematopoietic Both 0.4887 0.987 0.951,1.02 3179 28632 0.5105 0.987 0.951,1.03 3006 28428
288.3 Eosinophilia hematopoietic Both 0.0123 1.26 1.05,1.5 128 1278 0.005248 1.3 1.08,1.56 123 1267
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.5888 0.984 0.929,1.04 1259 12554 0.7047 0.976 0.858,1.11 261 2756
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.5248 0.973 0.896,1.06 615 6123 0.6223 0.979 0.9,1.07 598 6093
289.4 Lymphadenitis hematopoietic Both 0.8241 0.996 0.96,1.03 3186 28420 0.6982 0.993 0.956,1.03 3049 28221
289.5 Diseases of spleen hematopoietic Both 0.1059 0.909 0.81,1.02 313 3130 0.1148 0.909 0.807,1.02 291 3092
289.8 Polycythemia, secondary hematopoietic Both 0.1778 0.899 0.77,1.05 182 1820 0.1256 0.885 0.757,1.03 179 1809
289.9 Abnormality of red blood cells hematopoietic Both 0.6209 0.969 0.856,1.1 281 2776 0.7047 0.976 0.858,1.11 261 2756
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.984 0.999 0.937,1.07 1040 9399 0.6471 0.981 0.902,1.07 617 6278
290.1 Dementias mental disorders Both 0.6637 1.02 0.923,1.13 407 3816 0.4121 0.889 0.671,1.18 53 500
290.11 Alzheimer's disease mental disorders Both 0.9226 1.01 0.825,1.24 104 984 0.9268 0.99 0.807,1.22 102 964
290.12 Dementia with cerebral degenerations mental disorders Both 0.526 0.923 0.721,1.18 71 705 0.4457 0.907 0.705,1.17 69 681
290.13 Senile dementia mental disorders Both 0.6561 0.971 0.853,1.11 257 2376 0.6998 0.974 0.854,1.11 250 2327
290.16 Vascular dementia mental disorders Both 0.4188 0.891 0.674,1.18 53 508 0.4121 0.889 0.671,1.18 53 500
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.7178 0.985 0.908,1.07 634 6242 0.7907 0.989 0.91,1.07 602 6150
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.8222 0.991 0.913,1.08 642 6369 0.6471 0.981 0.902,1.07 617 6278
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.8531 0.996 0.951,1.04 1977 19673 0.8913 0.996 0.945,1.05 1489 15293
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.3243 0.921 0.783,1.08 161 1610 0.3475 0.925 0.785,1.09 159 1595
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.8851 1.01 0.906,1.12 364 3634 0.9817 1.0 0.898,1.12 354 3596
291.8 Alteration of consciousness mental disorders Both 0.8872 1.0 0.953,1.06 1563 15497 0.8913 0.996 0.945,1.05 1489 15293
292 Neurological disorders mental disorders Both 0.3155 1.02 0.985,1.05 4340 31695 0.07943 1.17 0.982,1.39 133 1411
292.1 Aphasia/speech disturbance mental disorders Both 0.2123 1.03 0.981,1.09 1554 15459 0.5702 1.05 0.891,1.23 157 1596
292.11 Aphasia mental disorders Both 0.4932 1.03 0.944,1.13 516 5142 0.5272 1.03 0.94,1.13 491 5072
292.12 Symbolic dysfunction mental disorders Both 0.5943 1.04 0.89,1.23 162 1620 0.5702 1.05 0.891,1.23 157 1596
292.2 Mild cognitive impairment mental disorders Both 0.542 1.04 0.919,1.18 276 2716 0.561 1.04 0.915,1.18 263 2667
292.3 Memory loss mental disorders Both 0.389 1.02 0.97,1.08 1405 13752 0.4266 1.02 0.968,1.08 1362 13567
292.4 Altered mental status mental disorders Both 0.1746 1.03 0.986,1.08 1885 18096 0.2094 1.03 0.983,1.08 1778 17836
292.5 Transient alteration of awareness mental disorders Both 0.09772 0.906 0.807,1.02 327 3237 0.03981 0.881 0.781,0.994 306 3196
292.6 Hallucinations mental disorders Both 0.03467 1.2 1.01,1.42 144 1429 0.07943 1.17 0.982,1.39 133 1411
293 Symptoms involving head and neck mental disorders Both 0.6109 1.03 0.917,1.16 304 3036 0.2661 1.02 0.985,1.06 3600 31991
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.1291 1.03 0.992,1.06 3691 32427 0.2661 1.02 0.985,1.06 3600 31991
295 Schizophrenia and other psychotic disorders mental disorders Both 0.2249 0.951 0.878,1.03 664 6564 0.1545 0.934 0.85,1.03 491 5138
295.1 Schizophrenia mental disorders Both 0.5534 0.942 0.774,1.15 111 1080 0.5888 0.947 0.777,1.15 109 1071
295.2 Paranoid disorders mental disorders Both 0.5236 0.931 0.749,1.16 86 856 0.6546 0.95 0.76,1.19 82 848
295.3 Psychosis mental disorders Both 0.2259 0.946 0.864,1.04 527 5206 0.1545 0.934 0.85,1.03 491 5138
296 Mood disorders mental disorders Both 0.2884 1.01 0.989,1.04 12028 17942 0.0871 1.02 0.997,1.05 10577 17771
296.1 Bipolar mental disorders Both 0.5768 0.982 0.92,1.05 994 9331 0.5309 0.979 0.917,1.05 982 9273
296.2 Depression mental disorders Both 0.177 1.02 0.993,1.04 11641 17941 0.0871 1.02 0.997,1.05 10577 17771
296.22 Major depressive disorder mental disorders Both 0.1038 1.02 0.996,1.05 10773 17942 0.0871 1.02 0.997,1.05 10577 17771
297 Suicidal ideation or attempt mental disorders Both 0.7345 0.987 0.912,1.07 696 6932 0.02344 0.84 0.723,0.977 195 2000
297.1 Suicidal ideation mental disorders Both 0.881 1.01 0.922,1.1 559 5575 0.9354 0.996 0.911,1.09 545 5539
297.2 Suicide or self-inflicted injury mental disorders Both 0.06457 0.871 0.751,1.01 201 2010 0.02344 0.84 0.723,0.977 195 2000
300 Anxiety disorders mental disorders Both 0.2917 1.01 0.989,1.04 12038 17949 0.9183 0.996 0.915,1.08 602 6063
300.1 Anxiety disorder mental disorders Both 0.4519 1.01 0.985,1.03 11352 17942 0.8492 1.01 0.932,1.09 713 7171
300.11 Generalized anxiety disorder mental disorders Both 0.01622 1.04 1.01,1.08 4496 17788 0.01738 1.04 1.01,1.08 4412 17616
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.0955 1.06 0.99,1.13 957 9152 0.08128 1.06 0.993,1.14 938 9090
300.13 Phobia mental disorders Both 0.8872 1.01 0.931,1.09 731 7231 0.8492 1.01 0.932,1.09 713 7171
300.3 Obsessive-compulsive disorders mental disorders Both 0.007586 1.2 1.05,1.38 223 2230 0.01023 1.2 1.04,1.37 219 2215
300.4 Dysthymic disorder mental disorders Both 0.6561 1.01 0.963,1.06 1798 13630 0.6902 1.01 0.961,1.06 1762 13507
300.8 Acute reaction to stress mental disorders Both 0.5309 1.04 0.929,1.15 359 3536 0.5598 1.03 0.926,1.15 355 3513
300.9 Posttraumatic stress disorder mental disorders Both 0.8356 1.01 0.928,1.1 612 6113 0.9183 0.996 0.915,1.08 602 6063
301 Personality disorders mental disorders Both 0.03981 1.12 1.01,1.25 363 3626 0.02344 1.19 1.02,1.38 184 1860
301.2 Antisocial/borderline personality disorder mental disorders Both 0.01202 1.21 1.04,1.4 187 1868 0.02344 1.19 1.02,1.38 184 1860
302 Sexual and gender identity disorders mental disorders Both 0.2958 1.05 0.962,1.14 608 6055 0.1596 1.09 0.968,1.22 321 3190
302.1 Decreased libido mental disorders Both 0.2018 1.08 0.961,1.21 325 3233 0.1596 1.09 0.968,1.22 321 3190
303 Psychogenic and somatoform disorders mental disorders Both 0.04365 1.07 1.0,1.14 1030 10064 0.05129 1.07 0.999,1.14 903 9044
303.1 Dissociative disorder mental disorders Both 0.3597 1.09 0.903,1.32 115 1144 0.3556 1.09 0.904,1.32 114 1135
303.3 Psychogenic disorder mental disorders Both 0.4656 1.03 0.954,1.11 736 7330 0.7798 1.02 0.907,1.14 334 3345
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.6607 1.03 0.916,1.15 340 3376 0.7798 1.02 0.907,1.14 334 3345
303.4 Somatoform disorder mental disorders Both 0.0309 1.08 1.01,1.15 925 9106 0.05129 1.07 0.999,1.14 903 9044
304 Adjustment reaction mental disorders Both 0.156 1.03 0.989,1.07 2840 17464 0.1841 1.03 0.987,1.07 2767 17294
305.2 Eating disorder mental disorders Both 0.9977 1.0 0.921,1.09 650 6500 0.9333 0.996 0.917,1.08 636 6464
306 Other mental disorder mental disorders Both 0.7129 1.01 0.953,1.07 1254 10907 0.3581 1.04 0.953,1.14 509 5181
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.2972 0.946 0.853,1.05 418 2847 0.2844 0.945 0.852,1.05 415 2839
306.9 Tension headache mental disorders Both 0.2704 1.05 0.961,1.15 521 5210 0.3581 1.04 0.953,1.14 509 5181
312 Conduct disorders mental disorders Both 0.4966 0.948 0.814,1.11 189 1890 0.875 0.977 0.73,1.31 52 523
312.3 Impulse control disorder mental disorders Both 0.9506 0.991 0.744,1.32 53 530 0.875 0.977 0.73,1.31 52 523
313 Pervasive developmental disorders mental disorders Both 0.7031 1.01 0.952,1.08 1148 11078 0.7311 1.05 0.81,1.35 58 582
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.7261 1.01 0.948,1.08 1012 9899 0.798 1.01 0.945,1.08 1004 9811
313.2 Tics and stuttering mental disorders Both 0.9661 1.01 0.78,1.3 60 593 0.7311 1.05 0.81,1.35 58 582
315 Develomental delays and disorders mental disorders Both 0.06026 0.905 0.815,1.0 401 3990 0.1954 0.9 0.767,1.06 171 1771
315.1 Learning disorder mental disorders Both 0.3013 0.867 0.662,1.14 60 599 0.1734 0.824 0.623,1.09 57 593
315.2 Speech and language disorder mental disorders Both 0.2825 0.919 0.787,1.07 182 1801 0.1954 0.9 0.767,1.06 171 1771
316 Substance addiction and disorders mental disorders Both 0.1637 1.03 0.989,1.07 2799 26014 0.8017 1.01 0.921,1.11 482 5116
316.1 Polyneuropathy due to drugs mental disorders Both 0.6577 1.02 0.932,1.12 518 5180 0.8017 1.01 0.921,1.11 482 5116
317 Alcohol-related disorders mental disorders Both 0.7328 1.01 0.962,1.06 1948 17547 0.0195 0.872 0.778,0.978 325 3291
317.1 Alcoholism mental disorders Both 0.4385 1.02 0.969,1.08 1517 14733 0.0195 0.872 0.778,0.978 325 3291
317.11 Alcoholic liver damage mental disorders Both 0.0195 0.874 0.78,0.978 335 3336 0.0195 0.872 0.778,0.978 325 3291
318 Tobacco use disorder mental disorders Both 0.6607 0.995 0.971,1.02 9473 26924 0.5715 0.993 0.969,1.02 9302 26599
320 Meningitis neurological Both 0.2679 1.07 0.952,1.2 319 3181 0.2636 1.07 0.951,1.2 303 3129
323 Encephalitis neurological Both 0.7464 0.972 0.816,1.16 148 1475 0.6471 1.05 0.863,1.27 121 1231
323.8 Encephalitis, non-infectious neurological Both 0.7278 1.03 0.857,1.25 125 1245 0.6471 1.05 0.863,1.27 121 1231
324 Other CNS infection and poliomyelitis neurological Both 0.3155 1.07 0.938,1.22 245 2440 0.2958 1.07 0.941,1.22 244 2388
327 Sleep disorders neurological Both 0.873 1.0 0.98,1.02 11517 26652 0.1726 1.2 0.922,1.57 54 541
327.1 Hypersomnia neurological Both 0.7816 0.992 0.939,1.05 1403 13919 0.6823 0.988 0.935,1.05 1361 13752
327.3 Sleep apnea neurological Both 0.7925 0.997 0.972,1.02 8293 26193 0.975 1.0 0.972,1.03 6401 25244
327.31 Central/nonobstroctive sleep apnea neurological Both 0.9616 1.0 0.895,1.12 326 3234 0.6714 1.03 0.914,1.15 315 3191
327.32 Obstructive sleep apnea neurological Both 0.8913 0.998 0.971,1.03 6534 25537 0.975 1.0 0.972,1.03 6401 25244
327.4 Insomnia neurological Both 0.342 1.02 0.983,1.05 4197 25860 0.171 0.952 0.886,1.02 859 8640
327.41 Organic or persistent insomnia neurological Both 0.2014 0.955 0.89,1.02 881 8743 0.171 0.952 0.886,1.02 859 8640
327.5 Parasomnia neurological Both 0.881 0.993 0.902,1.09 459 4583 0.859 0.991 0.899,1.09 442 4508
327.6 Circadian rhythm sleep disorder neurological Both 0.006761 1.24 1.06,1.45 174 1738 0.007586 1.24 1.06,1.45 168 1722
327.7 Sleep related movement disorders neurological Both 0.4009 1.02 0.969,1.08 1364 13620 0.1726 1.2 0.922,1.57 54 541
327.71 Restless legs syndrome neurological Both 0.975 0.999 0.941,1.06 1214 12132 0.9506 1.0 0.944,1.06 1196 11982
327.72 Sleep related leg cramps neurological Both 0.1285 1.23 0.943,1.6 55 550 0.1726 1.2 0.922,1.57 54 541
331 Other cerebral degenerations neurological Both 0.5176 0.973 0.894,1.06 602 5935 0.2218 0.932 0.831,1.04 327 3366
331.1 Hydrocephalus neurological Both 0.4775 0.954 0.836,1.09 246 2447 0.4385 0.949 0.831,1.08 241 2417
331.9 Cerebral degeneration, unspecified neurological Both 0.4325 0.957 0.857,1.07 349 3423 0.2218 0.932 0.831,1.04 327 3366
332 Parkinson's disease neurological Both 0.07762 0.902 0.804,1.01 333 3321 0.1102 0.91 0.811,1.02 329 3254
333 Extrapyramidal disease and abnormal movement disorders neurological Both 1.0 1.0 0.957,1.05 2169 20920 0.4305 1.1 0.864,1.41 62 629
333.1 Essential tremor neurological Both 0.6577 0.98 0.897,1.07 551 5488 0.6124 0.977 0.893,1.07 532 5402
333.2 Myoclonus neurological Both 0.1262 0.864 0.717,1.04 117 1160 0.125 0.859 0.708,1.04 108 1144
333.4 Torsion dystonia neurological Both 0.01862 1.16 1.03,1.31 266 2646 0.05012 1.13 1.0,1.28 261 2615
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.3954 1.11 0.871,1.42 64 640 0.4305 1.1 0.864,1.41 62 629
334 Degenerative disease of the spinal cord neurological Both 0.857 1.01 0.938,1.08 874 8734 0.3724 0.879 0.662,1.17 54 566
334.1 Spinocerebellar disease neurological Both 0.869 1.02 0.797,1.31 64 631 0.787 1.04 0.805,1.33 62 625
334.2 Anterior horn cell disease neurological Both 0.6324 0.95 0.77,1.17 92 920 0.3724 0.879 0.662,1.17 54 566
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.4909 0.908 0.69,1.19 57 570 0.3724 0.879 0.662,1.17 54 566
335 Multiple sclerosis neurological Both 0.0912 0.904 0.805,1.02 330 3284 0.07244 0.898 0.798,1.01 322 3256
337 Disorders of the autonomic nervous system neurological Both 0.5012 0.969 0.886,1.06 528 5257 0.5768 0.956 0.818,1.12 175 1815
337.1 Peripheral autonomic neuropathy neurological Both 0.8318 0.984 0.846,1.14 185 1837 0.5768 0.956 0.818,1.12 175 1815
338 Pain neurological Both 0.5834 0.994 0.974,1.01 16189 22165 0.2965 0.986 0.961,1.01 8041 21907
338.1 Acute pain neurological Both 0.7745 0.997 0.975,1.02 12567 22166 0.7816 0.997 0.975,1.02 12330 21919
338.2 Chronic pain neurological Both 0.3105 0.987 0.962,1.01 8223 22154 0.2965 0.986 0.961,1.01 8041 21907
339 Other headache syndromes neurological Both 0.3828 1.01 0.986,1.04 8578 27793 0.3802 1.01 0.986,1.04 8392 27457
340 Migraine neurological Both 0.1901 1.02 0.99,1.05 5377 24263 0.865 1.0 0.964,1.04 2828 18473
340.1 Migrain with aura neurological Both 0.9863 1.0 0.961,1.04 2862 18665 0.865 1.0 0.964,1.04 2828 18473
341 Other demyelinating diseases of central nervous system neurological Both 0.2679 0.892 0.729,1.09 111 1105 0.2564 0.888 0.723,1.09 107 1094
342 Hemiplegia neurological Both 0.8913 0.993 0.891,1.11 360 3589 0.8035 0.986 0.882,1.1 343 3544
343 Infantile cerebral palsy neurological Both 0.4305 0.91 0.721,1.15 75 750 0.4764 0.918 0.725,1.16 73 747
344 Other paralytic syndromes neurological Both 0.5164 1.03 0.944,1.12 564 5640 0.5 1.03 0.945,1.12 547 5569
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.9441 0.998 0.954,1.04 2084 20790 0.7464 0.992 0.947,1.04 1910 19391
345.1 Epilepsy neurological Both 0.1119 1.07 0.984,1.16 607 6053 0.2056 1.07 0.965,1.18 417 4284
345.11 Generalized convulsive epilepsy neurological Both 0.4581 1.06 0.913,1.23 196 1960 0.413 1.06 0.917,1.24 189 1941
345.12 Partial epilepsy neurological Both 0.235 1.06 0.962,1.17 434 4333 0.2056 1.07 0.965,1.18 417 4284
345.3 Convulsions neurological Both 0.9247 0.998 0.952,1.05 1967 19598 0.7464 0.992 0.947,1.04 1910 19391
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.8356 0.982 0.829,1.16 142 1404 0.8414 1.02 0.812,1.29 77 877
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.6531 0.986 0.93,1.05 1196 11927 0.4246 0.976 0.918,1.04 1146 11794
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.8356 0.976 0.78,1.22 87 860 0.9727 0.996 0.794,1.25 86 846
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.6457 0.95 0.765,1.18 90 884 0.8414 1.02 0.812,1.29 77 877
347 Cataplexy and narcolepsy neurological Both 0.6223 1.06 0.831,1.36 67 670 0.7295 1.05 0.814,1.34 66 665
348 Other conditions of brain neurological Both 0.6622 1.01 0.959,1.07 1424 14226 0.1862 1.03 0.985,1.08 1943 19749
348.2 Cerebral edema and compression of brain neurological Both 0.9931 1.0 0.927,1.08 747 7463 0.8054 0.99 0.918,1.07 723 7395
348.4 Cerebral cysts neurological Both 0.7129 0.973 0.842,1.12 195 1945 0.7447 0.976 0.843,1.13 190 1928
348.7 Coma neurological Both 0.3715 0.93 0.792,1.09 162 1620 0.335 0.922 0.781,1.09 151 1606
348.8 Encephalopathy, not elsewhere classified neurological Both 0.5445 0.975 0.9,1.06 636 6331 0.4797 0.97 0.893,1.05 594 6238
348.9 Other conditions of brain, NOS neurological Both 0.139 1.04 0.989,1.08 2001 19979 0.1862 1.03 0.985,1.08 1943 19749
349 Other and unspecified disorders of the nervous system neurological Both 0.6546 1.02 0.945,1.1 775 7750 0.6683 1.02 0.943,1.1 753 7660
350 Abnormal movement neurological Both 0.3741 1.01 0.984,1.04 5109 32314 0.3112 1.05 0.954,1.16 436 4410
350.1 Abnormal involuntary movements neurological Both 0.309 0.978 0.938,1.02 2464 24243 0.375 0.981 0.94,1.02 2379 23918
350.2 Abnormality of gait neurological Both 0.1294 1.03 0.991,1.07 2979 25007 0.2228 1.02 0.986,1.06 2888 24669
350.3 Lack of coordination neurological Both 0.02188 1.09 1.01,1.17 773 7693 0.03236 1.08 1.01,1.17 750 7602
350.5 Abnormal reflex neurological Both 0.5152 1.06 0.893,1.25 143 1430 0.5023 1.06 0.893,1.26 140 1419
350.6 Disturbances of sensation of smell and taste neurological Both 0.3112 1.05 0.954,1.16 448 4480 0.3112 1.05 0.954,1.16 436 4410
351 Other peripheral nerve disorders neurological Both 0.4159 0.988 0.96,1.02 5685 28844 0.4426 0.989 0.96,1.02 5528 28500
352 Disorders of other cranial nerves neurological Both 0.2667 0.969 0.918,1.02 1412 14120 0.8375 0.991 0.913,1.08 626 6308
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.6412 0.977 0.886,1.08 440 4393 0.5943 0.974 0.882,1.07 433 4336
352.2 Facial nerve disorders [CN7] neurological Both 0.7852 0.989 0.911,1.07 640 6400 0.8375 0.991 0.913,1.08 626 6308
353 Nerve root and plexus disorders neurological Both 0.7998 0.995 0.96,1.03 3295 28097 0.2904 1.13 0.904,1.4 89 914
353.1 Nerve plexus lesions neurological Both 0.0389 0.881 0.781,0.993 308 3077 0.03236 0.876 0.776,0.989 304 3039
353.2 Nerve root lesions neurological Both 0.1371 1.18 0.95,1.46 94 930 0.2904 1.13 0.904,1.4 89 914
355 Complex regional/central pain syndrome neurological Both 0.3811 0.956 0.864,1.06 419 4170 0.8091 1.01 0.931,1.1 631 6441
355.1 Chronic pain syndrome neurological Both 0.6223 1.02 0.942,1.11 654 6509 0.8091 1.01 0.931,1.1 631 6441
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.1393 0.963 0.916,1.01 1728 17176 0.1524 0.964 0.916,1.01 1660 16923
357 Inflammatory and toxic neuropathy neurological Both 0.08128 0.964 0.924,1.0 2467 24091 0.05888 0.96 0.92,1.0 2352 23756
358 Myoneural disorders neurological Both 0.04266 0.929 0.866,0.997 845 8441 0.7603 0.967 0.776,1.2 83 834
358.1 Myasthenia gravis neurological Both 0.8954 1.01 0.819,1.26 85 850 0.7603 0.967 0.776,1.2 83 834
359 Muscular dystrophies and other myopathies neurological Both 0.1469 0.949 0.885,1.02 868 8655 0.03388 0.923 0.858,0.994 797 8194
359.1 Muscular dystrophies neurological Both 0.2838 1.16 0.883,1.53 52 520 0.2553 1.17 0.89,1.55 51 515
359.2 Myopathy neurological Both 0.1038 0.942 0.876,1.01 833 8306 0.03388 0.923 0.858,0.994 797 8194
360 Disorders of the globe sense organs Both 0.526 1.07 0.872,1.31 102 1013 0.877 0.983 0.794,1.22 94 996
361 Retinal detachments and defects sense organs Both 0.8831 1.01 0.921,1.1 528 5265 0.4121 0.943 0.821,1.08 218 2167
361.1 Retinal detachment with retinal defect sense organs Both 0.4236 0.945 0.824,1.08 225 2226 0.4121 0.943 0.821,1.08 218 2167
362 Other retinal disorders sense organs Both 0.3404 0.98 0.939,1.02 2489 18838 0.2042 0.91 0.786,1.05 200 1967
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.3206 0.973 0.922,1.03 1529 12328 0.1803 0.96 0.905,1.02 1276 10708
362.21 Macular degeneration, dry sense organs Both 0.5508 1.04 0.921,1.17 313 2650 0.869 1.01 0.894,1.14 302 2585
362.22 Macular degeneration, wet sense organs Both 0.8147 1.02 0.836,1.26 108 881 0.9572 1.01 0.817,1.24 105 865
362.23 Cystoid macular degeneration of retina sense organs Both 0.1603 0.916 0.811,1.04 285 2777 0.1603 0.915 0.809,1.04 281 2727
362.26 Macular puckering of retina sense organs Both 0.03162 0.914 0.842,0.992 645 6254 0.02399 0.908 0.836,0.987 623 6127
362.27 Drusen (degenerative) of retina sense organs Both 0.3126 0.942 0.84,1.06 335 3205 0.1738 0.921 0.818,1.04 318 3135
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.3126 0.971 0.916,1.03 1323 10928 0.1803 0.96 0.905,1.02 1276 10708
362.3 Other nondiabetic retinopathy sense organs Both 0.9817 0.999 0.921,1.08 653 6476 0.7244 1.02 0.905,1.15 289 2882
362.31 Separation of retinal layers sense organs Both 0.6714 1.03 0.91,1.16 296 2938 0.7244 1.02 0.905,1.15 289 2882
362.4 Retinal vascular changes and abnomalities sense organs Both 0.826 0.989 0.899,1.09 449 4295 0.6223 0.976 0.885,1.08 441 4222
362.6 Peripheral retinal degenerations sense organs Both 0.3954 0.945 0.829,1.08 262 2600 0.4055 0.945 0.828,1.08 258 2557
362.7 Hereditary retinal dystrophies sense organs Both 0.3467 0.913 0.756,1.1 124 1233 0.3776 0.918 0.76,1.11 124 1218
362.8 Retinal hemorrhage/ischemia sense organs Both 0.3451 1.08 0.92,1.27 160 1570 0.3581 1.08 0.916,1.28 149 1544
362.9 Retinal edema sense organs Both 0.2084 0.911 0.787,1.05 202 2001 0.2042 0.91 0.786,1.05 200 1967
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.7244 0.981 0.882,1.09 375 3665 0.9572 1.0 0.878,1.15 237 2390
363.3 Chorioretinal scars sense organs Both 0.8995 1.01 0.885,1.15 249 2430 0.9572 1.0 0.878,1.15 237 2390
364 Corneal opacity and other disorders of cornea sense organs Both 0.05754 1.07 0.998,1.15 809 7919 0.5715 0.931 0.728,1.19 66 661
364.1 Corneal opacity sense organs Both 0.9772 1.0 0.89,1.13 294 2930 0.975 1.0 0.889,1.13 286 2886
364.2 Corneal edema sense organs Both 0.2239 1.15 0.919,1.43 84 819 0.228 1.15 0.916,1.44 80 805
364.4 Corneal degenerations sense organs Both 0.3459 1.06 0.938,1.2 274 2719 0.3837 1.06 0.933,1.2 263 2669
364.5 Corneal dystrophy sense organs Both 0.06166 1.11 0.995,1.23 377 3673 0.3236 1.08 0.93,1.25 198 1973
364.51 Fuchs' dystrophy sense organs Both 0.2371 1.09 0.945,1.26 207 2008 0.3236 1.08 0.93,1.25 198 1973
364.9 Cornea replaced by transplant sense organs Both 0.5728 0.933 0.732,1.19 69 677 0.5715 0.931 0.728,1.19 66 661
365 Glaucoma sense organs Both 0.9397 1.0 0.956,1.05 1986 17152 0.5585 0.955 0.817,1.12 175 1673
365.1 Open-angle glaucoma sense organs Both 0.9506 1.0 0.916,1.1 523 4963 0.7907 0.983 0.867,1.11 273 2554
365.11 Primary open angle glaucoma sense organs Both 0.7482 0.98 0.866,1.11 281 2609 0.7907 0.983 0.867,1.11 273 2554
365.2 Primary angle-closure glaucoma sense organs Both 0.5272 0.952 0.816,1.11 179 1707 0.5585 0.955 0.817,1.12 175 1673
366 Cataract sense organs Both 0.52 0.99 0.962,1.02 6335 23476 0.863 0.997 0.961,1.03 3697 20136
366.1 Nonsenile Cataract sense organs Both 0.06918 0.857 0.725,1.01 163 1622 0.05623 0.846 0.713,1.0 155 1591
366.2 Senile cataract sense organs Both 0.9484 0.999 0.964,1.04 3827 20410 0.863 0.997 0.961,1.03 3697 20136
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.4966 1.01 0.983,1.04 6553 31745 0.7889 0.991 0.927,1.06 937 9534
367.1 Myopia sense organs Both 0.8851 0.997 0.963,1.03 3578 28818 0.7178 0.993 0.959,1.03 3504 28479
367.2 Astigmatism sense organs Both 0.8872 0.997 0.959,1.04 2892 26106 0.7798 0.994 0.956,1.03 2830 25775
367.4 Presbyopia sense organs Both 0.4592 1.01 0.977,1.05 3297 24582 0.4966 1.01 0.976,1.05 3223 24236
367.8 Hypermetropia sense organs Both 0.4236 0.978 0.927,1.03 1504 14729 0.4457 0.979 0.927,1.03 1473 14515
367.9 Blindness and low vision sense organs Both 0.8395 0.993 0.93,1.06 976 9663 0.7889 0.991 0.927,1.06 937 9534
368 Visual disturbances sense organs Both 0.7586 1.01 0.973,1.04 4287 32818 0.6776 0.954 0.765,1.19 80 871
368.1 Amblyopia sense organs Both 0.5117 0.969 0.882,1.06 484 4830 0.6324 0.977 0.888,1.07 477 4761
368.2 Diplopia and disorders of binocular vision sense organs Both 0.7925 0.99 0.922,1.06 822 8186 0.7516 0.988 0.919,1.06 796 8068
368.3 Anisometropia sense organs Both 0.9594 1.0 0.859,1.17 166 1648 0.9705 0.997 0.852,1.17 164 1621
368.4 Visual field defects sense organs Both 0.4467 1.03 0.959,1.1 879 8777 0.3614 1.03 0.963,1.11 852 8645
368.9 Subjective visual disturbances sense organs Both 0.9863 0.999 0.93,1.07 829 8268 0.6776 0.954 0.765,1.19 80 871
368.91 Psychophysical visual disturbances sense organs Both 0.857 0.981 0.794,1.21 89 885 0.6776 0.954 0.765,1.19 80 871
369 Infection of the eye sense organs Both 0.798 1.01 0.963,1.05 2328 22262 0.826 1.01 0.959,1.05 1934 19190
369.2 Eye infection, viral sense organs Both 0.6442 1.03 0.921,1.14 372 3688 0.6095 1.03 0.923,1.15 361 3653
369.5 Conjunctivitis, infectious sense organs Both 0.7482 1.01 0.962,1.06 1974 19408 0.826 1.01 0.959,1.05 1934 19190
370 Keratitis sense organs Both 0.2163 1.04 0.977,1.11 1051 10280 0.5105 0.943 0.791,1.12 137 1410
370.1 Corneal ulcer sense organs Both 0.208 1.11 0.944,1.3 164 1630 0.2239 1.11 0.94,1.3 159 1610
370.2 Superficial keratitis sense organs Both 0.9016 1.01 0.908,1.12 394 3916 0.9863 1.0 0.902,1.11 383 3851
370.3 Keratoconjunctivitis sense organs Both 0.1324 1.07 0.98,1.17 531 5159 0.5105 0.943 0.791,1.12 137 1410
370.31 Keratoconjunctivitis sicca sense organs Both 0.865 0.986 0.834,1.17 150 1432 0.5105 0.943 0.791,1.12 137 1410
371 Inflammation of the eye sense organs Both 0.1371 1.03 0.991,1.07 3269 26161 0.0871 0.827 0.666,1.03 96 962
371.1 Uveitis, noninfectious or NOS sense organs Both 0.5702 0.971 0.876,1.08 394 3892 0.3767 0.954 0.859,1.06 375 3844
371.2 Conjunctivitis, noninfectious sense organs Both 0.9162 0.996 0.919,1.08 651 6462 0.4355 0.964 0.881,1.06 523 5221
371.21 Allergic conjunctivitis sense organs Both 0.4634 0.967 0.884,1.06 532 5279 0.4355 0.964 0.881,1.06 523 5221
371.3 Inflammation of eyelids sense organs Both 0.03802 1.04 1.0,1.09 2523 21781 0.0871 0.827 0.666,1.03 96 962
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.1151 0.843 0.682,1.04 100 979 0.0871 0.827 0.666,1.03 96 962
372 Disorders of conjunctiva sense organs Both 0.0955 1.06 0.989,1.14 827 8153 0.191 1.05 0.976,1.13 797 8018
374 Other disorders of eyelids sense organs Both 0.2786 1.03 0.98,1.07 2093 18512 0.6442 1.02 0.944,1.1 737 7301
374.1 Ectropion or entropion sense organs Both 0.4808 1.04 0.931,1.16 337 3251 0.4966 1.04 0.928,1.17 321 3190
374.2 Lagophthalmos sense organs Both 0.2716 1.09 0.936,1.26 192 1900 0.3243 1.08 0.927,1.26 186 1871
374.3 Ptosis of eyelid sense organs Both 0.02512 1.08 1.01,1.16 817 8140 0.01698 1.09 1.02,1.17 790 8003
374.6 Dermatochalasis sense organs Both 0.7047 1.01 0.941,1.09 759 7426 0.6442 1.02 0.944,1.1 737 7301
375 Disorders of lacrimal system sense organs Both 0.8453 0.996 0.956,1.04 2683 21054 0.4955 0.962 0.861,1.08 345 3501
375.1 Dry eyes sense organs Both 0.9817 1.0 0.961,1.04 2966 21823 0.9638 0.999 0.96,1.04 2864 21548
375.2 Epiphora sense organs Both 0.3873 0.953 0.853,1.06 356 3540 0.4955 0.962 0.861,1.08 345 3501
376 Disorders of the orbit sense organs Both 0.2328 1.08 0.954,1.21 285 2814 0.26 1.07 0.95,1.21 279 2786
377 Disorders of optic nerve and visual pathways sense organs Both 0.877 0.994 0.921,1.07 706 7010 0.9817 0.999 0.908,1.1 455 4563
377.1 Optic atrophy sense organs Both 0.6918 0.971 0.841,1.12 200 1997 0.6295 0.964 0.833,1.12 193 1974
377.3 Optic neuritis/neuropathy sense organs Both 0.929 1.0 0.914,1.1 468 4627 0.9817 0.999 0.908,1.1 455 4563
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.8954 0.996 0.932,1.06 969 9602 0.4315 0.951 0.838,1.08 263 2694
378.1 Strabismus (not specified as paralytic) sense organs Both 0.6324 1.02 0.94,1.11 617 6131 0.547 1.03 0.944,1.12 602 6052
378.2 Nystagmus and other irregular eye movements sense organs Both 0.8872 1.01 0.853,1.2 138 1371 0.8356 1.02 0.856,1.21 133 1353
378.5 Paralytic strabismus sense organs Both 0.3228 0.939 0.83,1.06 275 2720 0.4315 0.951 0.838,1.08 263 2694
379 Other disorders of eye sense organs Both 0.1954 1.02 0.988,1.06 3593 24835 0.5383 1.02 0.953,1.1 844 8501
379.1 Scleritis and episcleritis sense organs Both 0.9594 1.0 0.847,1.19 140 1379 0.8241 1.02 0.857,1.21 134 1361
379.2 Disorders of vitreous body sense organs Both 0.456 1.02 0.975,1.06 2559 18709 0.4009 1.02 0.976,1.06 2471 18442
379.3 Aphakia and other disorders of lens sense organs Both 0.02089 1.31 1.04,1.65 87 838 0.02455 1.31 1.03,1.65 83 832
379.4 Anomalies of pupillary function sense organs Both 0.4581 1.05 0.921,1.2 231 2303 0.7015 1.03 0.898,1.17 228 2274
379.5 Disorders of iris and ciliary body sense organs Both 0.1807 0.907 0.787,1.05 215 2128 0.7762 1.04 0.803,1.34 61 608
379.51 Pigmentary iris degeneration sense organs Both 0.7586 1.04 0.805,1.35 61 610 0.7762 1.04 0.803,1.34 61 608
379.9 Pain, swelling or discharge of eye sense organs Both 0.6166 1.02 0.95,1.09 870 8594 0.5383 1.02 0.953,1.1 844 8501
380 Disorders of external ear sense organs Both 0.175 0.965 0.917,1.02 1634 15553 0.1849 0.968 0.924,1.02 1928 18304
380.1 Otitis externa sense organs Both 0.7079 0.988 0.93,1.05 1124 11213 0.6887 0.987 0.928,1.05 1097 11036
380.4 Impacted cerumen sense organs Both 0.1754 0.968 0.924,1.01 1985 18630 0.1849 0.968 0.924,1.02 1928 18304
381 Otitis media and Eustachian tube disorders sense organs Both 0.9397 1.0 0.966,1.04 3291 29339 0.5105 1.04 0.923,1.17 290 2923
381.1 Otitis media sense organs Both 0.8414 0.996 0.955,1.04 2402 23549 0.4699 0.983 0.939,1.03 1993 19931
381.11 Suppurative and unspecified otitis media sense organs Both 0.5445 0.986 0.942,1.03 2037 20175 0.4699 0.983 0.939,1.03 1993 19931
381.2 Eustachian tube disorders sense organs Both 0.4989 1.02 0.964,1.08 1393 13815 0.4416 1.02 0.967,1.08 1371 13626
381.3 Mastoiditis & related conditions sense organs Both 0.2761 0.902 0.749,1.09 126 1260 0.2404 0.894 0.741,1.08 124 1249
381.9 Otorrhea sense organs Both 0.3963 1.05 0.935,1.19 297 2960 0.5105 1.04 0.923,1.17 290 2923
382 Otalgia sense organs Both 0.2985 0.971 0.919,1.03 1425 14188 0.257 0.968 0.916,1.02 1393 14013
383 Otosclerosis sense organs Both 0.542 1.06 0.882,1.27 112 1120 0.5297 1.06 0.883,1.27 112 1101
384 Other disorders of tympanic membrane sense organs Both 0.5834 0.971 0.876,1.08 397 3962 0.984 1.0 0.892,1.12 313 3144
384.4 Perforation of tympanic membrane sense organs Both 0.8892 1.01 0.899,1.13 318 3180 0.984 1.0 0.892,1.12 313 3144
385 Other disorders of middle ear and mastoid sense organs Both 0.6823 0.977 0.876,1.09 358 3580 0.3273 0.905 0.741,1.11 103 1010
385.3 Cholesteatoma sense organs Both 0.8433 1.01 0.889,1.15 245 2450 0.8128 1.02 0.891,1.16 243 2420
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.3097 0.901 0.737,1.1 103 1025 0.3273 0.905 0.741,1.11 103 1010
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.618 0.986 0.933,1.04 1441 14255 0.4345 1.01 0.982,1.04 5172 31212
386.1 Meniere's disease sense organs Both 0.1096 0.897 0.784,1.02 248 2464 0.1084 0.895 0.782,1.02 243 2429
386.2 Peripheral or central vertigo sense organs Both 0.975 0.999 0.941,1.06 1209 11971 0.3184 0.965 0.898,1.04 867 8649
386.21 Central origin vertigo sense organs Both 0.3589 0.968 0.902,1.04 883 8759 0.3184 0.965 0.898,1.04 867 8649
386.3 Labyrinthitis sense organs Both 0.2564 0.964 0.906,1.03 1099 10904 0.1941 0.959 0.9,1.02 1077 10774
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.3055 1.02 0.986,1.05 5315 31605 0.4345 1.01 0.982,1.04 5172 31212
388 Other disorders of ear sense organs Both 0.3733 0.965 0.892,1.04 699 6960 0.4742 0.971 0.897,1.05 683 6868
389 Hearing loss sense organs Both 0.103 1.02 0.995,1.05 6285 31750 0.1578 0.859 0.696,1.06 99 1000
389.1 Sensorineural hearing loss sense organs Both 0.0389 1.04 1.0,1.08 3130 24231 0.06026 1.04 0.998,1.08 3051 23893
389.2 Conductive hearing loss sense organs Both 0.2535 0.956 0.885,1.03 717 7169 0.2046 0.951 0.879,1.03 702 7079
389.3 Degenerative and vascular disorders of ear sense organs Both 0.4853 0.938 0.784,1.12 143 1338 0.4395 0.931 0.776,1.12 140 1310
389.4 Tinnitus sense organs Both 0.3119 1.03 0.976,1.08 1677 16701 0.3499 1.02 0.974,1.08 1638 16471
389.5 Disorders of acoustic nerve sense organs Both 0.2371 0.882 0.717,1.09 101 1010 0.1578 0.859 0.696,1.06 99 1000
394 Rheumatic disease of the heart valves circulatory system Both 0.1483 1.04 0.984,1.11 1177 11253 0.2612 1.06 0.96,1.16 450 4541
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.8318 0.987 0.872,1.12 284 2766 0.7691 0.981 0.865,1.11 270 2714
394.2 Mitral valve disease circulatory system Both 0.07586 1.1 0.99,1.22 378 3735 0.08913 1.1 0.986,1.22 366 3667
394.3 Aortic valve disease circulatory system Both 0.3793 1.08 0.912,1.27 150 1465 0.4385 1.07 0.903,1.27 145 1437
394.7 Disease of tricuspid valve circulatory system Both 0.4325 1.04 0.945,1.14 468 4624 0.2612 1.06 0.96,1.16 450 4541
395 Heart valve disorders circulatory system Both 0.3882 1.02 0.979,1.06 3169 23926 0.2594 1.04 0.971,1.12 849 8064
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.3396 1.02 0.975,1.08 1754 16787 0.2864 1.03 0.977,1.08 1709 16529
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.1545 1.04 0.986,1.09 1619 13932 0.1496 1.04 0.986,1.1 1569 13688
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.7852 0.985 0.886,1.1 373 3704 1.0 1.0 0.897,1.11 354 3628
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.6397 0.95 0.767,1.18 84 831 0.4325 0.916 0.735,1.14 80 824
395.6 Heart valve replaced circulatory system Both 0.3266 1.04 0.966,1.11 878 8213 0.2594 1.04 0.971,1.12 849 8064
396 Abnormal heart sounds circulatory system Both 0.7015 1.01 0.973,1.04 3754 28453 0.6281 1.01 0.974,1.04 3653 28087
401 Hypertension circulatory system Both 0.5248 1.01 0.985,1.03 18784 19071 0.005248 1.07 1.02,1.12 1951 12819
401.1 Essential hypertension circulatory system Both 0.6546 1.01 0.983,1.03 18655 19070 0.7464 1.0 0.981,1.03 18285 18905
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.1318 1.03 0.99,1.08 2599 12045 0.3112 1.03 0.976,1.08 1917 10773
401.21 Hypertensive heart disease circulatory system Both 0.1683 1.06 0.974,1.16 556 4628 0.2208 1.06 0.967,1.16 535 4566
401.22 Hypertensive chronic kidney disease circulatory system Both 0.317 1.03 0.976,1.08 2015 10909 0.3112 1.03 0.976,1.08 1917 10773
401.3 Other hypertensive complications circulatory system Both 0.003388 1.07 1.02,1.13 2027 12961 0.005248 1.07 1.02,1.12 1951 12819
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.9661 0.999 0.954,1.05 2132 15248 0.9817 0.999 0.954,1.05 2078 15100
411 Ischemic Heart Disease circulatory system Both 0.08128 1.03 0.997,1.05 6970 25468 0.1941 1.08 0.962,1.21 320 3189
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.1567 1.06 0.979,1.14 702 6842 0.1581 1.06 0.978,1.14 683 6721
411.2 Myocardial infarction circulatory system Both 0.08128 1.04 0.996,1.08 2849 17983 0.08128 1.04 0.996,1.08 2769 17726
411.3 Angina pectoris circulatory system Both 0.1871 1.03 0.984,1.08 1904 15218 0.3236 1.02 0.976,1.08 1852 14992
411.4 Coronary atherosclerosis circulatory system Both 0.2477 1.02 0.988,1.05 5938 22890 0.9638 0.996 0.819,1.21 114 1120
411.41 Aneurysm and dissection of heart circulatory system Both 0.8974 0.987 0.813,1.2 117 1149 0.9638 0.996 0.819,1.21 114 1120
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.3972 1.01 0.982,1.05 4877 21174 0.5117 1.01 0.978,1.05 4748 20889
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.191 1.08 0.964,1.2 335 3247 0.1941 1.08 0.962,1.21 320 3189
414 Other forms of chronic heart disease circulatory system Both 0.375 1.02 0.977,1.06 2360 18485 0.8531 1.01 0.919,1.11 475 4767
414.2 ASCVD circulatory system Both 0.7621 1.01 0.926,1.11 492 4846 0.8531 1.01 0.919,1.11 475 4767
415 Pulmonary heart disease circulatory system Both 0.3177 1.02 0.981,1.06 2726 25061 0.05754 1.09 0.997,1.18 570 5796
415.1 Acute pulmonary heart disease circulatory system Both 0.7925 0.993 0.942,1.05 1510 15045 0.7621 0.992 0.94,1.05 1451 14808
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.7534 0.992 0.94,1.05 1507 15014 0.7621 0.992 0.94,1.05 1451 14808
415.2 Chronic pulmonary heart disease circulatory system Both 0.1472 1.04 0.986,1.1 1506 14839 0.05754 1.09 0.997,1.18 570 5796
415.21 Primary pulmonary hypertension circulatory system Both 0.0955 1.07 0.988,1.17 592 5901 0.05754 1.09 0.997,1.18 570 5796
416 Cardiomegaly circulatory system Both 0.2692 1.04 0.971,1.11 935 9293 0.191 1.05 0.977,1.12 891 9136
418 Nonspecific chest pain circulatory system Both 0.4227 1.01 0.986,1.03 10015 28233 0.8337 1.01 0.947,1.07 1149 11664
418.1 Precordial pain circulatory system Both 0.8892 1.0 0.946,1.07 1193 11816 0.8337 1.01 0.947,1.07 1149 11664
420 Carditis circulatory system Both 0.03467 1.06 1.0,1.13 1275 12633 0.2228 1.05 0.968,1.15 578 5892
420.1 Myocarditis circulatory system Both 0.5333 0.93 0.74,1.17 76 752 0.6761 0.951 0.753,1.2 72 738
420.2 Pericarditis circulatory system Both 0.04169 1.08 1.0,1.17 684 6830 0.1892 1.15 0.933,1.42 89 902
420.21 Acute pericarditis circulatory system Both 0.001862 1.31 1.1,1.55 144 1435 0.01778 1.24 1.04,1.47 136 1418
420.22 Chronic pericarditis circulatory system Both 0.1493 1.17 0.947,1.43 92 912 0.1892 1.15 0.933,1.42 89 902
420.3 Endocarditis circulatory system Both 0.2582 1.05 0.965,1.14 602 5990 0.2228 1.05 0.968,1.15 578 5892
425 Cardiomyopathy circulatory system Both 0.1432 1.04 0.987,1.09 1617 15758 0.695 0.952 0.746,1.22 67 704
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.1429 1.04 0.987,1.1 1557 15170 0.6412 1.04 0.879,1.23 152 1509
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.4603 1.06 0.906,1.24 171 1699 0.507 1.06 0.899,1.24 166 1668
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.6561 1.04 0.879,1.23 154 1540 0.6412 1.04 0.879,1.23 152 1509
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.9397 1.01 0.882,1.14 248 2480 0.8395 0.986 0.861,1.13 227 2444
425.8 Other cardiomyopathy circulatory system Both 0.7161 0.957 0.755,1.21 71 709 0.695 0.952 0.746,1.22 67 704
426 Cardiac conduction disorders circulatory system Both 0.1986 1.02 0.991,1.04 9881 21221 0.004365 1.13 1.04,1.22 612 5628
426.2 Atrioventricular [AV] block circulatory system Both 0.06166 1.05 0.997,1.11 1527 9610 0.1432 1.13 0.961,1.32 156 1469
426.21 First degree AV block circulatory system Both 0.1435 1.05 0.984,1.12 1064 7510 0.1832 1.05 0.979,1.12 1033 7415
426.22 Mobitz II AV block circulatory system Both 0.0302 1.34 1.03,1.75 56 513 0.02291 1.37 1.04,1.79 55 500
426.23 Second degree AV block circulatory system Both 0.4898 1.06 0.902,1.24 161 1459 0.3221 1.08 0.923,1.27 157 1425
426.24 Atrioventricular block, complete circulatory system Both 0.5035 1.04 0.931,1.16 357 3041 0.3811 1.05 0.941,1.17 345 2998
426.25 Other heart block circulatory system Both 0.2286 1.1 0.941,1.29 161 1489 0.1432 1.13 0.961,1.32 156 1469
426.3 Bundle branch block circulatory system Both 0.4581 1.02 0.969,1.07 1775 11373 0.3565 1.04 0.96,1.12 699 6135
426.31 Right bundle branch block circulatory system Both 0.9908 1.0 0.939,1.06 1101 8763 0.9954 1.0 0.938,1.07 1061 8662
426.32 Left bundle branch block circulatory system Both 0.2244 1.05 0.971,1.13 721 6217 0.3565 1.04 0.96,1.12 699 6135
426.4 Anomalous atrioventricular excitation circulatory system Both 0.7656 0.961 0.739,1.25 62 611 0.673 0.944 0.723,1.23 60 606
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.3006 1.01 0.987,1.04 8452 21094 0.2944 1.01 0.987,1.04 8201 20942
426.8 Other cardiac conduction disorders circulatory system Both 0.9817 0.999 0.907,1.1 456 4529 0.9016 0.994 0.9,1.1 431 4469
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.0138 1.08 1.02,1.14 1261 8802 0.004365 1.13 1.04,1.22 612 5628
426.91 Cardiac pacemaker in situ circulatory system Both 0.03467 1.08 1.01,1.16 836 6124 0.0257 1.09 1.01,1.17 810 6043
426.92 Cardiac defibrillator in situ circulatory system Both 0.004365 1.12 1.04,1.22 628 5698 0.004365 1.13 1.04,1.22 612 5628
427 Cardiac dysrhythmias circulatory system Both 0.1694 1.02 0.993,1.04 14018 21321 0.6501 1.01 0.972,1.05 3348 20006
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.04266 1.05 1.0,1.1 1882 14769 0.04786 1.07 1.0,1.15 857 7881
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.3373 1.03 0.97,1.09 1193 11216 0.4236 1.03 0.965,1.09 1148 11110
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.03311 1.08 1.01,1.15 892 7975 0.04786 1.07 1.0,1.15 857 7881
427.2 Atrial fibrillation and flutter circulatory system Both 0.03467 1.04 1.0,1.08 4194 15493 0.05495 1.05 0.999,1.11 1547 9565
427.21 Atrial fibrillation circulatory system Both 0.04169 1.04 1.0,1.08 4097 15312 0.04898 1.04 1.0,1.08 3967 15178
427.22 Atrial flutter circulatory system Both 0.04571 1.06 1.0,1.11 1598 9674 0.05495 1.05 0.999,1.11 1547 9565
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.5058 1.01 0.982,1.04 7129 21276 0.5546 1.01 0.98,1.04 6917 21124
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.3707 1.05 0.948,1.16 419 4137 0.2661 1.07 0.952,1.2 308 3145
427.41 Ventricular fibrillation and flutter circulatory system Both 0.8241 0.982 0.839,1.15 167 1670 0.7674 0.976 0.833,1.14 163 1646
427.42 Cardiac arrest circulatory system Both 0.3141 1.06 0.947,1.18 321 3186 0.2661 1.07 0.952,1.2 308 3145
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.06607 1.03 0.998,1.06 5521 21271 0.07413 1.03 0.997,1.06 5350 21119
427.6 Premature beats circulatory system Both 0.0302 1.06 1.01,1.11 1820 13218 0.6966 1.02 0.929,1.12 499 4816
427.61 Supraventricular premature beats circulatory system Both 0.6026 1.02 0.936,1.12 522 4879 0.6966 1.02 0.929,1.12 499 4816
427.7 Tachycardia NOS circulatory system Both 0.3597 1.02 0.982,1.05 3980 21286 0.4355 1.01 0.979,1.05 3838 21134
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.4178 1.03 0.956,1.11 738 6224 0.3963 1.03 0.957,1.12 715 6141
427.9 Palpitations circulatory system Both 0.5012 1.01 0.976,1.05 3420 20157 0.6501 1.01 0.972,1.05 3348 20006
428 Congestive heart failure; nonhypertensive circulatory system Both 0.04786 1.04 1.0,1.08 3326 19946 0.2564 1.04 0.975,1.1 1143 10467
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.07244 1.04 0.997,1.08 2965 19130 0.06026 1.04 0.998,1.08 2853 18900
428.2 Heart failure NOS circulatory system Both 0.1023 1.03 0.993,1.08 2781 17962 0.0955 1.04 0.994,1.08 2674 17739
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.4753 1.02 0.964,1.08 1288 11396 0.3926 1.03 0.967,1.09 1237 11223
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.1919 1.04 0.98,1.1 1208 10616 0.2564 1.04 0.975,1.1 1143 10467
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.6368 0.994 0.971,1.02 9394 27581 0.2046 1.06 0.971,1.15 574 5726
429.1 Heart transplant/surgery circulatory system Both 0.8222 1.01 0.939,1.08 823 8070 0.7834 1.01 0.939,1.09 796 7949
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.7568 0.995 0.963,1.03 4445 23965 0.7015 0.993 0.961,1.03 4306 23717
429.3 Symptoms involving cardiovascular system circulatory system Both 0.863 1.0 0.976,1.03 7147 27443 0.9817 1.0 0.973,1.03 6942 27178
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.3342 1.04 0.959,1.13 591 5816 0.2046 1.06 0.971,1.15 574 5726
430 Intracranial hemorrhage circulatory system Both 0.9247 1.0 0.925,1.09 633 6305 0.2291 1.09 0.945,1.27 194 1983
430.1 Subarachnoid hemorrhage circulatory system Both 0.9683 0.997 0.869,1.14 230 2300 0.5346 0.956 0.831,1.1 221 2260
430.2 Intracerebral hemorrhage circulatory system Both 0.4603 1.04 0.931,1.17 314 3132 0.597 1.03 0.917,1.16 296 3075
430.3 Subdural hemorrhage circulatory system Both 0.3236 1.08 0.931,1.24 202 2017 0.2291 1.09 0.945,1.27 194 1983
433 Cerebrovascular disease circulatory system Both 0.9484 1.0 0.969,1.03 4361 26660 0.8356 1.01 0.923,1.1 516 5215
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.6383 1.01 0.96,1.07 1533 12978 0.4406 1.11 0.852,1.45 60 585
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.5395 1.05 0.903,1.21 188 1858 0.5272 1.05 0.904,1.22 185 1824
433.12 Cerebral atherosclerosis circulatory system Both 0.3999 1.12 0.86,1.46 61 599 0.4406 1.11 0.852,1.45 60 585
433.2 Occlusion of cerebral arteries circulatory system Both 0.6823 1.01 0.963,1.06 1926 17593 0.8433 1.0 0.957,1.05 1814 16735
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.7178 1.01 0.962,1.06 1862 17011 0.8433 1.0 0.957,1.05 1814 16735
433.3 Cerebral ischemia circulatory system Both 0.5834 1.01 0.968,1.06 2122 18040 0.52 1.02 0.967,1.07 1763 15787
433.31 Transient cerebral ischemia circulatory system Both 0.4467 1.02 0.971,1.07 1812 16062 0.52 1.02 0.967,1.07 1763 15787
433.5 Cerebral aneurysm circulatory system Both 0.5508 0.969 0.874,1.07 408 4070 0.5902 0.972 0.876,1.08 402 4006
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.207 1.07 0.963,1.19 383 3803 0.2239 1.07 0.96,1.19 364 3730
433.8 Late effects of cerebrovascular disease circulatory system Both 0.9354 1.0 0.918,1.1 534 5286 0.8356 1.01 0.923,1.1 516 5215
440 Atherosclerosis circulatory system Both 0.05754 1.05 0.998,1.1 1946 16499 0.2729 1.05 0.966,1.13 674 6660
440.1 Atherosclerosis of renal artery circulatory system Both 0.2089 1.1 0.949,1.27 187 1855 0.2138 1.1 0.947,1.27 179 1827
440.2 Atherosclerosis of the extremities circulatory system Both 0.1365 1.05 0.986,1.11 1166 11265 0.3758 1.03 0.961,1.11 790 7829
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.03802 1.17 1.01,1.35 183 1815 0.06607 1.15 0.991,1.33 175 1789
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.4325 1.03 0.958,1.11 812 7979 0.3758 1.03 0.961,1.11 790 7829
440.9 Atherosclerosis of aorta circulatory system Both 0.2588 1.05 0.968,1.13 702 6800 0.2729 1.05 0.966,1.13 674 6660
441 Vascular insufficiency of intestine circulatory system Both 0.5224 1.03 0.934,1.14 407 4039 0.4592 0.932 0.772,1.12 117 1191
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.2773 1.08 0.94,1.24 206 2025 0.5188 1.05 0.908,1.21 195 1992
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.4295 0.929 0.773,1.12 122 1207 0.4592 0.932 0.772,1.12 117 1191
442 Other aneurysm circulatory system Both 0.3707 1.02 0.977,1.07 2309 18098 0.6152 0.971 0.865,1.09 324 3244
442.1 Aortic aneurysm circulatory system Both 0.369 1.02 0.973,1.08 1703 13812 0.871 1.01 0.941,1.07 961 8845
442.11 Abdominal aortic aneurysm circulatory system Both 0.929 1.0 0.94,1.07 992 9021 0.871 1.01 0.941,1.07 961 8845
442.2 Aneurysm of iliac artery circulatory system Both 0.869 0.987 0.845,1.15 177 1769 0.9863 0.999 0.853,1.17 171 1740
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.6124 1.04 0.882,1.24 137 1357 0.5741 1.05 0.885,1.25 134 1328
442.4 Arterial dissection circulatory system Both 0.2218 1.11 0.94,1.31 156 1555 0.3516 1.08 0.917,1.28 154 1530
442.8 Aneurysm of other specified artery circulatory system Both 0.7362 0.981 0.875,1.1 330 3300 0.6152 0.971 0.865,1.09 324 3244
443 Peripheral vascular disease circulatory system Both 0.1968 1.03 0.986,1.07 2355 20353 0.2655 1.03 0.979,1.08 1698 14902
443.1 Raynaud's syndrome circulatory system Both 0.1496 1.06 0.978,1.16 608 6051 0.2023 1.06 0.971,1.15 599 5962
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.9311 1.01 0.847,1.2 141 1375 0.8872 1.01 0.849,1.21 138 1352
443.8 Other specified peripheral vascular diseases circulatory system Both 0.07413 1.04 0.996,1.09 1899 17476 0.0912 1.04 0.993,1.09 1856 17203
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.1991 1.03 0.983,1.08 1747 15154 0.2655 1.03 0.979,1.08 1698 14902
444 Arterial embolism and thrombosis circulatory system Both 0.01072 1.11 1.02,1.2 675 6732 0.1349 1.15 0.959,1.37 126 1262
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.2259 1.08 0.952,1.23 240 2392 0.1012 1.11 0.979,1.27 233 2357
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.07586 1.17 0.983,1.4 129 1282 0.1349 1.15 0.959,1.37 126 1262
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.08318 1.1 0.987,1.22 367 3641 0.1648 1.1 0.961,1.26 218 2252
446.4 Wegener's granulomatosis circulatory system Both 0.415 1.1 0.88,1.36 86 857 0.5321 1.07 0.86,1.34 84 844
446.5 Giant cell arteritis circulatory system Both 0.00537 1.47 1.12,1.94 59 547 0.00537 1.5 1.13,1.99 54 540
446.9 Arteritis NOS circulatory system Both 0.157 1.1 0.963,1.26 230 2285 0.1648 1.1 0.961,1.26 218 2252
447 Other disorders of arteries and arterioles circulatory system Both 0.03311 1.05 1.0,1.1 2116 18819 0.2767 1.05 0.964,1.14 620 6189
447.1 Stricture of artery circulatory system Both 0.4305 0.962 0.872,1.06 435 4322 0.4477 0.963 0.872,1.06 425 4251
447.7 Aortic ectasia circulatory system Both 0.3141 1.04 0.961,1.13 637 6315 0.2767 1.05 0.964,1.14 620 6189
448 Disease of capillaries circulatory system Both 0.3819 1.03 0.961,1.11 853 8472 0.4603 1.03 0.956,1.1 831 8341
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.6982 0.99 0.942,1.04 1701 17006 0.6808 0.989 0.941,1.04 1654 16747
451 Phlebitis and thrombophlebitis circulatory system Both 0.6397 1.02 0.936,1.11 582 5764 0.8872 1.01 0.867,1.18 183 1871
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.6138 1.04 0.894,1.21 190 1888 0.8872 1.01 0.867,1.18 183 1871
452 Other venous embolism and thrombosis circulatory system Both 0.2799 0.981 0.948,1.02 3773 25068 0.2588 1.11 0.924,1.34 116 1171
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.3319 1.07 0.934,1.22 228 2277 0.3908 1.06 0.925,1.22 220 2249
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.1714 0.972 0.933,1.01 2623 22444 0.09333 0.965 0.925,1.01 2518 22188
452.8 Postphlebitic syndrome circulatory system Both 0.2432 1.12 0.927,1.35 119 1181 0.2588 1.11 0.924,1.34 116 1171
453 Chronic venous hypertension circulatory system Both 0.867 1.01 0.869,1.18 173 1715 0.7063 1.03 0.883,1.2 170 1694
454 Varicose veins circulatory system Both 0.2951 1.02 0.98,1.07 2206 20243 0.354 1.03 0.969,1.09 1160 11623
454.1 Varicose veins of lower extremity circulatory system Both 0.2523 1.03 0.98,1.08 1908 17574 0.354 1.03 0.969,1.09 1160 11623
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.2992 1.03 0.972,1.1 1182 11754 0.354 1.03 0.969,1.09 1160 11623
455 Hemorrhoids circulatory system Both 0.08128 0.971 0.94,1.0 4379 24588 0.06607 0.969 0.938,1.0 4276 24320
456 Chronic venous insufficiency [CVI] circulatory system Both 0.1153 1.04 0.991,1.08 2303 20367 0.1393 1.03 0.989,1.08 2243 20140
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.3112 1.02 0.977,1.08 1946 14131 0.1493 1.04 0.987,1.09 1778 13464
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.5559 1.04 0.918,1.17 287 2845 0.5483 1.04 0.918,1.18 279 2801
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.2673 1.03 0.979,1.08 1841 13661 0.1493 1.04 0.987,1.09 1778 13464
458 Hypotension circulatory system Both 0.8414 1.0 0.971,1.04 4073 28546 0.5093 1.01 0.977,1.05 3485 27150
458.1 Orthostatic hypotension circulatory system Both 0.9057 0.996 0.935,1.06 1031 10176 0.6998 0.987 0.925,1.05 979 10035
458.2 Iatrogenic hypotension circulatory system Both 0.04365 1.07 1.0,1.15 911 9084 0.0631 1.07 0.996,1.14 882 8947
458.9 Hypotension NOS circulatory system Both 0.3908 1.02 0.981,1.05 3641 27465 0.5093 1.01 0.977,1.05 3485 27150
459 Other disorders of circulatory system circulatory system Both 0.3055 1.02 0.983,1.05 3553 27674 0.1535 1.03 0.989,1.07 2682 23364
459.1 Hemorrhage NOS circulatory system Both 0.4083 0.965 0.888,1.05 619 6159 0.235 0.949 0.871,1.03 591 6069
459.7 Blood vessel replaced circulatory system Both 0.561 0.958 0.829,1.11 203 2030 0.5383 0.955 0.826,1.11 201 1993
459.9 Circulatory disease NEC circulatory system Both 0.166 1.03 0.988,1.07 2757 23656 0.1535 1.03 0.989,1.07 2682 23364
464 Acute sinusitis respiratory Both 0.4178 0.986 0.952,1.02 3675 26562 0.3499 0.983 0.949,1.02 3622 26262
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.7145 1.0 0.979,1.03 7223 30143 0.955 0.997 0.892,1.11 337 3407
465.2 Acute pharyngitis respiratory Both 0.7295 1.01 0.973,1.04 3967 26715 0.6653 1.01 0.974,1.04 3883 26434
465.4 Acute laryngitis and tracheitis respiratory Both 0.877 1.01 0.904,1.13 345 3441 0.955 0.997 0.892,1.11 337 3407
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.7889 1.01 0.955,1.06 1431 14130 0.7638 1.01 0.955,1.06 1414 13991
471 Nasal polyps respiratory Both 0.007413 1.14 1.04,1.25 475 4727 0.01122 1.13 1.03,1.24 467 4689
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.3837 1.03 0.969,1.08 1344 13251 0.3396 1.03 0.971,1.09 1316 13095
473 Diseases of the larynx and vocal cords respiratory Both 0.798 0.994 0.953,1.04 2393 20985 0.9954 1.0 0.953,1.05 1835 17806
473.1 Chronic laryngitis respiratory Both 0.1023 1.25 0.957,1.63 57 562 0.1429 1.23 0.934,1.61 55 558
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.8872 0.994 0.908,1.09 517 5167 0.5741 0.974 0.889,1.07 506 5106
473.4 Voice disturbance respiratory Both 0.7551 1.01 0.961,1.06 1880 18033 0.9954 1.0 0.953,1.05 1835 17806
474 Acute and chronic tonsillitis respiratory Both 0.9594 1.0 0.926,1.08 685 6193 0.863 1.01 0.923,1.1 547 5124
474.1 Acute tonsillitis respiratory Both 0.3864 0.947 0.836,1.07 267 2507 0.4624 0.954 0.842,1.08 263 2490
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.9204 1.0 0.921,1.1 555 5166 0.863 1.01 0.923,1.1 547 5124
475 Chronic sinusitis respiratory Both 0.695 1.01 0.972,1.04 3434 23149 0.4227 0.967 0.89,1.05 635 6370
475.9 Postnasal drip respiratory Both 0.5395 0.975 0.899,1.06 651 6441 0.4227 0.967 0.89,1.05 635 6370
476 Allergic rhinitis respiratory Both 0.2244 1.01 0.991,1.04 10205 23354 0.2944 1.01 0.989,1.04 10010 23087
477 Epistaxis or throat hemorrhage respiratory Both 0.1538 1.05 0.981,1.13 895 8841 0.2188 1.05 0.974,1.12 858 8736
478 Throat pain respiratory Both 0.2265 0.932 0.831,1.04 325 3233 0.182 0.924 0.822,1.04 311 3193
479 Other upper respiratory disease respiratory Both 0.873 0.997 0.966,1.03 4428 23338 0.7727 0.995 0.963,1.03 4322 23072
480 Pneumonia respiratory Both 0.6887 1.01 0.976,1.04 4823 30881 0.9795 0.998 0.831,1.2 116 1158
480.1 Bacterial pneumonia respiratory Both 0.00182 1.12 1.04,1.2 860 8567 0.02344 1.32 1.04,1.67 75 811
480.11 Pneumococcal pneumonia respiratory Both 0.0955 1.1 0.984,1.22 372 3720 0.1387 1.09 0.973,1.22 345 3667
480.12 Pseudomonal pneumonia respiratory Both 0.2198 0.891 0.742,1.07 121 1192 0.0955 0.851 0.703,1.03 114 1171
480.13 MRSA pneumonia respiratory Both 0.04169 1.27 1.01,1.6 82 818 0.02344 1.32 1.04,1.67 75 811
480.2 Viral pneumonia respiratory Both 0.05012 1.18 1.0,1.4 147 1461 0.04571 1.2 1.0,1.43 127 1441
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.246 0.895 0.742,1.08 117 1170 0.3581 0.909 0.742,1.11 97 1159
480.5 Bronchopneumonia and lung abscess respiratory Both 0.8511 0.983 0.82,1.18 119 1175 0.9795 0.998 0.831,1.2 116 1158
481 Influenza respiratory Both 0.9977 1.0 0.937,1.07 990 9863 0.9661 1.0 0.937,1.07 945 9762
483 Acute bronchitis and bronchiolitis respiratory Both 0.7194 0.993 0.953,1.03 2615 24227 0.6855 0.992 0.952,1.03 2554 23983
495 Asthma respiratory Both 0.002399 1.04 1.01,1.07 6951 27725 0.003631 1.09 1.03,1.16 1229 12311
495.1 Chronic obstructive asthma respiratory Both 0.1556 1.08 0.971,1.2 341 3403 0.3681 1.13 0.868,1.46 58 583
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.2799 1.15 0.892,1.48 60 592 0.3681 1.13 0.868,1.46 58 583
495.2 Asthma with exacerbation respiratory Both 0.002754 1.09 1.03,1.16 1251 12442 0.003631 1.09 1.03,1.16 1229 12311
496 Chronic airway obstruction respiratory Both 0.008511 1.04 1.01,1.08 4444 23893 0.4819 1.04 0.936,1.15 413 4261
496.1 Emphysema respiratory Both 0.01 1.07 1.02,1.12 1831 16712 0.01479 1.06 1.01,1.12 1778 16433
496.2 Chronic bronchitis respiratory Both 0.004571 1.05 1.02,1.09 3357 22668 0.00302 1.06 1.02,1.1 2979 21378
496.21 Obstructive chronic bronchitis respiratory Both 0.001905 1.06 1.02,1.1 3040 21701 0.00302 1.06 1.02,1.1 2979 21378
496.3 Bronchiectasis respiratory Both 0.5508 1.03 0.933,1.14 435 4329 0.4819 1.04 0.936,1.15 413 4261
497 Bronchitis respiratory Both 0.1132 1.04 0.99,1.1 1481 14700 0.1574 1.04 0.985,1.1 1436 14509
498 Acute bronchospasm respiratory Both 0.07244 1.1 0.991,1.23 376 3745 0.03981 1.12 1.01,1.25 369 3708
499 Cystic fibrosis respiratory Both 0.1879 1.13 0.94,1.37 116 1160 0.1476 1.15 0.951,1.4 110 1146
500 Lung disease due to external agents respiratory Both 0.4121 1.04 0.944,1.15 428 4273 0.4603 1.1 0.853,1.42 60 626
500.1 Extrinsic allergic alveolitis respiratory Both 0.9057 1.01 0.812,1.26 81 810 0.8492 1.02 0.816,1.28 77 804
500.2 Pneumoconiosis respiratory Both 0.4797 1.09 0.853,1.4 65 640 0.4603 1.1 0.853,1.42 60 626
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.04467 1.1 1.0,1.2 514 5078 0.05248 1.1 0.999,1.2 492 5006
502 Postinflammatory pulmonary fibrosis respiratory Both 0.5058 1.03 0.947,1.12 623 6192 0.5546 1.03 0.943,1.12 595 6098
503 Pulmonary congestion and hypostasis respiratory Both 0.7261 0.986 0.913,1.07 690 6875 0.6053 0.979 0.904,1.06 658 6773
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.6501 1.02 0.928,1.13 447 4454 0.6053 1.04 0.906,1.19 234 2425
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.5188 1.04 0.916,1.19 247 2456 0.6053 1.04 0.906,1.19 234 2425
505 Other pulmonary inflamation or edema respiratory Both 0.5508 1.02 0.962,1.08 1352 13261 0.547 1.02 0.961,1.08 1287 13067
506 Empyema and pneumothorax respiratory Both 0.1122 1.03 0.992,1.08 2588 22332 0.1146 1.03 0.992,1.08 2507 22066
507 Pleurisy; pleural effusion respiratory Both 0.3926 0.982 0.941,1.02 2415 21828 0.2871 0.977 0.936,1.02 2303 21574
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.3741 0.979 0.935,1.03 2005 19256 0.2871 0.975 0.93,1.02 1917 19020
509 Respiratory failure, insufficiency, arrest respiratory Both 0.9247 0.998 0.961,1.04 3044 23898 0.9683 0.999 0.93,1.07 817 8366
509.1 Respiratory failure respiratory Both 0.7962 1.01 0.955,1.06 1466 14560 0.7063 1.01 0.957,1.07 1383 14383
509.2 Respiratory insufficiency respiratory Both 0.7586 1.01 0.945,1.08 928 9238 0.9354 1.0 0.936,1.07 876 9114
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.6209 0.987 0.936,1.04 1500 14783 0.6501 0.988 0.936,1.04 1466 14583
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.9817 0.999 0.932,1.07 848 8472 0.9683 0.999 0.93,1.07 817 8366
510 Other diseases of lung respiratory Both 0.4989 0.989 0.959,1.02 4671 30168 0.9078 0.989 0.824,1.19 119 1252
510.2 Lung transplant respiratory Both 0.7396 1.03 0.864,1.23 128 1274 0.9078 0.989 0.824,1.19 119 1252
512 Other symptoms of respiratory system respiratory Both 0.6934 0.996 0.975,1.02 14878 23476 0.9354 0.999 0.974,1.02 8420 23287
512.1 Wheezing respiratory Both 0.2355 1.04 0.976,1.11 1071 10626 0.2735 1.04 0.972,1.1 1040 10537
512.2 Painful respiration respiratory Both 0.6442 0.988 0.941,1.04 1765 17029 0.5395 0.984 0.936,1.03 1713 16887
512.3 Abnormal chest sounds respiratory Both 0.861 1.01 0.884,1.16 229 2261 0.9795 0.998 0.868,1.15 213 2227
512.7 Shortness of breath respiratory Both 0.1807 1.02 0.992,1.04 7928 23452 0.2065 1.02 0.991,1.04 7690 23272
512.8 Cough respiratory Both 0.7413 0.996 0.969,1.02 7280 23469 0.5943 0.993 0.966,1.02 7034 23289
512.9 Other dyspnea respiratory Both 0.9183 1.0 0.976,1.03 8658 23467 0.9354 0.999 0.974,1.02 8420 23287
513 Respiratory abnormalities respiratory Both 0.2455 1.01 0.991,1.04 10231 28110 0.2518 0.918 0.793,1.06 193 2010
513.3 Hypoventilation respiratory Both 0.7852 0.989 0.911,1.07 618 6146 0.5082 0.946 0.803,1.12 155 1635
513.31 Apnea respiratory Both 0.8472 1.01 0.902,1.13 314 3136 0.7228 1.02 0.91,1.15 308 3101
513.32 Orthopnea respiratory Both 0.6776 0.967 0.826,1.13 167 1662 0.5082 0.946 0.803,1.12 155 1635
513.4 Hyperventilation respiratory Both 0.003388 1.16 1.05,1.27 440 4383 0.003548 1.16 1.05,1.28 416 4318
513.8 Disorders of diaphragm respiratory Both 0.2535 0.921 0.799,1.06 206 2053 0.2518 0.918 0.793,1.06 193 2010
514 Abnormal findings examination of lungs respiratory Both 0.7447 1.01 0.974,1.04 4486 29229 0.5023 1.01 0.973,1.06 2413 22369
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.8954 0.99 0.852,1.15 193 1914 0.9977 1.0 0.858,1.17 182 1887
514.2 Solitary pulmonary nodule respiratory Both 0.4426 1.02 0.975,1.06 2489 22668 0.5023 1.01 0.973,1.06 2413 22369
516 Abnormal sputum respiratory Both 0.4508 1.03 0.948,1.13 565 5640 0.7047 1.02 0.924,1.12 436 4650
516.1 Hemoptysis respiratory Both 0.5483 1.03 0.936,1.13 473 4720 0.7047 1.02 0.924,1.12 436 4650
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.7161 1.01 0.976,1.04 5153 32053 0.5093 1.01 0.978,1.05 3898 28827
519.1 Tracheostomy complications respiratory Both 0.7943 0.979 0.837,1.15 176 1760 0.778 0.977 0.834,1.15 173 1737
519.2 Respiratory complications respiratory Both 0.7638 0.984 0.886,1.09 370 3696 0.7516 0.983 0.884,1.09 364 3650
519.8 Other diseases of respiratory system, NEC respiratory Both 0.6839 1.01 0.947,1.09 887 8857 0.7129 1.01 0.945,1.09 869 8745
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.4385 1.01 0.98,1.05 4043 29199 0.5093 1.01 0.978,1.05 3898 28827
520 Disorders of tooth development digestive Both 0.1138 0.907 0.804,1.02 291 2900 0.2163 0.902 0.767,1.06 169 1680
520.1 Hereditary disturbances in tooth structure digestive Both 0.1189 0.868 0.727,1.04 131 1301 0.1216 0.868 0.725,1.04 128 1286
520.2 Disturbances in tooth eruption digestive Both 0.1614 0.891 0.759,1.05 172 1693 0.2163 0.902 0.767,1.06 169 1680
521 Diseases of hard tissues of teeth digestive Both 0.879 1.01 0.932,1.09 719 7167 0.6808 1.02 0.938,1.1 647 6616
521.1 Dental caries digestive Both 0.8356 1.01 0.931,1.09 673 6709 0.6808 1.02 0.938,1.1 647 6616
522 Diseases of pulp and periapical tissues digestive Both 0.1754 1.07 0.969,1.19 408 4067 0.04074 1.12 1.0,1.26 330 3360
522.5 Periapical abscess digestive Both 0.05495 1.12 0.998,1.25 341 3404 0.04074 1.12 1.0,1.26 330 3360
523 Gingival and periodontal diseases digestive Both 0.4529 1.03 0.948,1.13 569 5690 0.8222 1.02 0.833,1.26 101 1013
523.1 Gingivitis digestive Both 0.597 0.949 0.781,1.15 117 1163 0.7362 0.966 0.792,1.18 111 1151
523.3 Periodontitis (acute or chronic) digestive Both 0.2009 1.08 0.959,1.22 294 2940 0.8222 1.02 0.833,1.26 101 1013
523.31 Acute periodontitis digestive Both 0.2844 1.07 0.943,1.22 251 2510 0.2168 1.09 0.953,1.24 245 2477
523.32 Chronic periodontitis digestive Both 0.9183 1.01 0.823,1.24 103 1030 0.8222 1.02 0.833,1.26 101 1013
524 Dentofacial anomalies, including malocclusion digestive Both 0.5984 0.969 0.861,1.09 308 3080 0.9705 0.997 0.86,1.16 185 1844
524.3 Anomalies of tooth position/malocclusion digestive Both 0.9441 0.995 0.858,1.15 186 1856 0.9705 0.997 0.86,1.16 185 1844
525 Other diseases of the teeth and supporting structures digestive Both 0.01096 1.09 1.02,1.17 853 8530 0.7311 1.02 0.91,1.14 313 3136
525.1 Loss of teeth or edentulism digestive Both 0.8356 1.01 0.903,1.13 318 3178 0.7311 1.02 0.91,1.14 313 3136
526 Diseases of the jaws digestive Both 0.5984 0.988 0.945,1.03 2140 21162 0.8035 0.987 0.89,1.09 391 3934
526.1 Cysts of the jaws digestive Both 0.3459 0.935 0.812,1.08 213 2123 0.3289 0.932 0.809,1.07 211 2093
526.3 Anomalies of jaw size/symmetry digestive Both 0.09772 0.885 0.766,1.02 206 2052 0.1 0.886 0.767,1.02 206 2038
526.4 Temporomandibular joint disorders digestive Both 0.3917 0.974 0.917,1.03 1178 11779 0.7798 1.01 0.93,1.1 590 5933
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.1718 0.954 0.891,1.02 941 9410 0.1374 0.95 0.887,1.02 925 9315
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.6531 1.02 0.937,1.11 600 5993 0.7798 1.01 0.93,1.1 590 5933
526.5 Inflammatory conditions of jaw digestive Both 0.9705 0.997 0.874,1.14 242 2405 0.7962 0.982 0.859,1.12 234 2374
526.9 Jaw disease NOS digestive Both 0.8017 0.987 0.891,1.09 399 3982 0.8035 0.987 0.89,1.09 391 3934
527 Diseases of the salivary glands digestive Both 0.9977 1.0 0.946,1.06 1362 13604 0.5957 0.961 0.829,1.11 191 1930
527.2 Sialoadenitis digestive Both 0.6839 0.977 0.872,1.09 320 3200 0.7551 0.982 0.876,1.1 317 3165
527.7 Disturbance of salivary secretion digestive Both 0.52 1.03 0.95,1.11 715 7141 0.3846 1.04 0.958,1.12 686 7024
527.8 Other specified diseases of the salivary glands digestive Both 0.5675 0.959 0.829,1.11 196 1960 0.5957 0.961 0.829,1.11 191 1930
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.4656 1.02 0.972,1.06 2077 20750 0.6039 0.955 0.802,1.14 132 1313
528.1 Stomatitis and mucositis digestive Both 0.3758 1.04 0.952,1.14 536 5360 0.3412 1.08 0.921,1.27 167 1679
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.9162 1.01 0.858,1.19 165 1650 0.8974 1.01 0.853,1.2 148 1619
528.12 Oral aphthae digestive Both 0.4775 1.06 0.903,1.24 170 1700 0.3412 1.08 0.921,1.27 167 1679
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.7709 1.02 0.879,1.19 185 1837 0.9954 1.0 0.858,1.16 181 1822
528.4 Cysts of oral soft tissues digestive Both 0.3119 0.9 0.734,1.1 110 1096 0.7015 1.05 0.818,1.35 67 668
528.41 Cyst of the salivary gland digestive Both 0.8375 1.03 0.8,1.32 68 679 0.7015 1.05 0.818,1.35 67 668
528.5 Diseases of lips digestive Both 0.3758 1.05 0.941,1.17 334 3340 0.354 1.05 0.943,1.18 327 3303
528.6 Leukoplakia of oral mucosa digestive Both 0.1096 0.85 0.696,1.04 113 1120 0.1429 0.861 0.704,1.05 110 1107
528.7 Sialolithiasis digestive Both 0.5861 0.953 0.8,1.13 132 1320 0.6039 0.955 0.802,1.14 132 1313
529 Diseases and other conditions of the tongue digestive Both 0.9376 1.0 0.919,1.1 541 5402 0.9661 1.0 0.842,1.2 133 1330
529.1 Glossitis digestive Both 0.5768 1.06 0.865,1.3 99 982 0.7586 1.03 0.841,1.27 98 975
529.6 Glossodynia digestive Both 0.9616 0.996 0.836,1.19 136 1355 0.9661 1.0 0.842,1.2 133 1330
530 Diseases of esophagus digestive Both 0.3365 0.989 0.968,1.01 13874 23034 0.04467 0.94 0.885,0.999 1165 11826
530.1 Esophagitis, GERD and related diseases digestive Both 0.2972 0.988 0.967,1.01 13419 23031 0.6067 1.05 0.882,1.24 143 1433
530.11 GERD digestive Both 0.2455 0.987 0.966,1.01 13059 23031 0.1549 0.984 0.962,1.01 12808 22792
530.12 Ulcer of esophagus digestive Both 0.4797 0.957 0.848,1.08 298 2973 0.271 0.933 0.823,1.06 284 2935
530.13 Barrett's esophagus digestive Both 0.4335 1.03 0.952,1.12 609 6080 0.5358 1.03 0.944,1.12 594 5985
530.14 Reflux esophagitis digestive Both 0.861 0.995 0.943,1.05 1483 14213 0.5572 0.984 0.932,1.04 1436 14039
530.15 Eosinophilic esophagitis digestive Both 0.6501 1.04 0.878,1.23 145 1441 0.6067 1.05 0.882,1.24 143 1433
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.03311 0.902 0.82,0.992 475 4742 0.0257 0.896 0.814,0.987 464 4687
530.3 Stricture and stenosis of esophagus digestive Both 0.009333 0.903 0.837,0.975 752 7474 0.008318 0.901 0.833,0.973 729 7372
530.5 Disorders of esophageal motility digestive Both 0.7516 0.984 0.891,1.09 434 4326 0.6501 0.977 0.883,1.08 421 4265
530.6 Diverticulum of esophagus, acquired digestive Both 0.912 1.01 0.836,1.22 121 1181 0.9931 1.0 0.826,1.21 119 1163
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.006026 1.39 1.1,1.76 70 700 0.008913 1.38 1.08,1.75 67 692
530.9 Heartburn digestive Both 0.06918 0.946 0.891,1.0 1198 11946 0.04467 0.94 0.885,0.999 1165 11826
531 Peptic ulcer (excl. esophageal) digestive Both 0.3365 0.975 0.926,1.03 1608 16066 0.09772 1.18 0.97,1.43 109 1119
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.6383 1.03 0.917,1.15 311 3103 0.9376 1.0 0.894,1.13 300 3041
531.2 Gastric ulcer digestive Both 0.526 0.978 0.913,1.05 884 8834 0.4831 0.975 0.909,1.05 861 8723
531.3 Duodenal ulcer digestive Both 0.3508 0.949 0.85,1.06 362 3613 0.3273 0.946 0.846,1.06 349 3549
531.4 Peptic ulcer, site unspecified digestive Both 0.9931 1.0 0.922,1.09 632 6313 0.9977 1.0 0.921,1.09 620 6220
531.5 Gastrojejunal ulcer digestive Both 0.1189 1.16 0.962,1.4 115 1143 0.09772 1.18 0.97,1.43 109 1119
532 Dysphagia digestive Both 0.4909 0.989 0.957,1.02 4457 22190 0.389 0.986 0.954,1.02 4344 21956
535 Gastritis and duodenitis digestive Both 0.1959 0.971 0.928,1.02 2129 21208 0.06761 0.939 0.878,1.0 951 9712
535.1 Acute gastritis digestive Both 0.865 0.994 0.924,1.07 814 8139 0.8551 0.993 0.923,1.07 793 8033
535.2 Atrophic gastritis digestive Both 0.6471 1.03 0.906,1.17 250 2500 0.5875 1.04 0.91,1.18 243 2471
535.6 Duodenitis digestive Both 0.6442 0.971 0.857,1.1 265 2650 0.6839 0.974 0.857,1.11 253 2610
535.8 Other specified gastritis digestive Both 0.7161 1.02 0.928,1.12 497 4964 0.8072 1.01 0.922,1.11 485 4880
535.9 Gastritis and duodenitis, NOS digestive Both 0.04571 0.935 0.875,0.999 985 9835 0.06761 0.939 0.878,1.0 951 9712
536 Disorders of function of stomach digestive Both 0.695 0.991 0.949,1.04 2251 22311 0.8035 0.994 0.945,1.05 1648 16626
536.3 Gastroparesis digestive Both 0.9772 1.0 0.913,1.1 489 4876 0.9141 1.01 0.916,1.1 472 4822
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.8531 0.99 0.886,1.11 334 3331 0.7211 0.98 0.876,1.1 328 3280
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.787 0.993 0.945,1.04 1699 16834 0.8035 0.994 0.945,1.05 1648 16626
537 Other disorders of stomach and duodenum digestive Both 0.4645 0.984 0.943,1.03 2357 23199 0.881 0.986 0.821,1.18 121 1250
537.1 Lesions of stomach and duodenum digestive Both 0.7079 1.03 0.867,1.24 128 1271 0.881 0.986 0.821,1.18 121 1250
539 Bariatric surgery digestive Both 0.9183 0.997 0.937,1.06 1118 11180 0.929 0.997 0.937,1.06 1105 11058
540 Appendiceal conditions digestive Both 0.1416 1.08 0.975,1.2 399 3990 0.09333 1.11 0.983,1.25 284 2886
540.1 Appendicitis digestive Both 0.04571 1.12 1.0,1.25 349 3490 0.09333 1.11 0.983,1.25 284 2886
540.11 Acute appendicitis digestive Both 0.08318 1.11 0.986,1.25 293 2930 0.09333 1.11 0.983,1.25 284 2886
550 Abdominal hernia digestive Both 0.1469 0.979 0.951,1.01 5517 31191 0.3724 0.972 0.913,1.03 1085 10823
550.1 Inguinal hernia digestive Both 0.1035 0.956 0.905,1.01 1427 13556 0.08511 0.953 0.901,1.01 1400 13314
550.2 Diaphragmatic hernia digestive Both 0.4571 0.984 0.942,1.03 2290 21266 0.4345 0.983 0.941,1.03 2240 20933
550.3 Femoral hernia digestive Both 0.07244 0.835 0.686,1.02 109 1082 0.07413 0.835 0.686,1.02 109 1065
550.4 Umbilical hernia digestive Both 0.542 0.98 0.92,1.04 1053 10514 0.5358 0.98 0.919,1.04 1036 10344
550.5 Ventral hernia digestive Both 0.03311 0.948 0.903,0.996 1826 18190 0.02692 0.946 0.901,0.994 1803 17894
550.6 Incisional hernia digestive Both 0.4227 0.975 0.916,1.04 1101 10999 0.3724 0.972 0.913,1.03 1085 10823
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.695 0.988 0.933,1.05 1275 12527 0.9863 0.999 0.905,1.1 430 4336
555.1 Regional enteritis digestive Both 0.9886 1.0 0.929,1.08 775 7701 0.7345 0.987 0.916,1.06 758 7640
555.2 Ulcerative colitis digestive Both 0.4603 0.972 0.902,1.05 768 7591 0.9863 0.999 0.905,1.1 430 4336
555.21 Ulcerative colitis (chronic) digestive Both 0.9099 1.01 0.912,1.11 438 4361 0.9863 0.999 0.905,1.1 430 4336
556 Ulceration of the lower GI tract digestive Both 0.4603 0.965 0.877,1.06 473 4719 0.09772 0.862 0.723,1.03 142 1475
556.1 Ulceration of intestine digestive Both 0.3251 0.95 0.858,1.05 412 4099 0.09772 0.862 0.723,1.03 142 1475
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.3597 0.924 0.781,1.09 152 1496 0.09772 0.862 0.723,1.03 142 1475
557 Intestinal malabsorption (non-celiac) digestive Both 0.2234 1.04 0.979,1.1 1306 12565 0.2786 1.07 0.949,1.2 296 3034
557.1 Celiac disease digestive Both 0.2624 1.07 0.952,1.2 305 3050 0.2786 1.07 0.949,1.2 296 3034
558 Noninfectious gastroenteritis digestive Both 0.8851 1.0 0.963,1.04 2706 20417 0.8054 0.995 0.955,1.04 2639 20256
559 Ileostomy status digestive Both 0.7727 0.989 0.919,1.06 773 7702 0.4797 0.974 0.904,1.05 760 7625
560 Intestinal obstruction without mention of hernia digestive Both 0.7674 1.01 0.966,1.05 2580 20303 0.9817 1.0 0.948,1.06 1456 14241
560.1 Paralytic ileus digestive Both 0.9036 1.0 0.95,1.06 1429 13524 0.9354 0.998 0.944,1.05 1399 13388
560.2 Impaction of intestine digestive Both 0.7907 0.983 0.865,1.12 257 2499 0.6039 0.966 0.849,1.1 252 2477
560.3 Peritoneal or intestinal adhesions digestive Both 0.6871 0.974 0.859,1.11 261 2599 0.5433 0.961 0.846,1.09 254 2570
560.4 Other intestinal obstruction digestive Both 0.8337 1.01 0.953,1.06 1489 14381 0.9817 1.0 0.948,1.06 1456 14241
561 Symptoms involving digestive system digestive Both 0.9311 1.0 0.975,1.03 7750 22039 0.4498 0.983 0.941,1.03 2295 18834
561.1 Diarrhea digestive Both 0.9078 1.0 0.973,1.03 5986 22042 0.8974 0.998 0.969,1.03 5765 21866
561.2 Flatulence digestive Both 0.6053 0.989 0.947,1.03 2358 18995 0.4498 0.983 0.941,1.03 2295 18834
562 Diverticulosis and diverticulitis digestive Both 0.4732 0.988 0.957,1.02 5014 18500 0.9441 1.0 0.946,1.06 1271 12118
562.1 Diverticulosis digestive Both 0.5188 0.989 0.958,1.02 4973 18448 0.3945 0.986 0.954,1.02 4861 18280
562.2 Diverticulitis digestive Both 0.8933 1.0 0.948,1.06 1292 12242 0.9441 1.0 0.946,1.06 1271 12118
563 Constipation digestive Both 0.4613 0.989 0.96,1.02 5639 22004 0.4009 0.987 0.958,1.02 5467 21828
564 Functional digestive disorders digestive Both 0.9204 1.0 0.977,1.03 9553 22037 0.2301 0.97 0.922,1.02 1718 16372
564.1 Irritable Bowel Syndrome digestive Both 0.1486 1.03 0.989,1.07 2751 17147 0.1656 1.03 0.988,1.07 2710 17020
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.9036 1.0 0.96,1.05 2348 18710 0.869 0.996 0.954,1.04 2279 18548
564.9 Personal history of diseases of digestive system digestive Both 0.3483 0.977 0.929,1.03 1762 16521 0.2301 0.97 0.922,1.02 1718 16372
565 Anal and rectal conditions digestive Both 0.8147 1.0 0.965,1.05 2533 24500 0.7447 0.989 0.924,1.06 909 9156
565.1 Anal and rectal polyp digestive Both 0.7834 0.991 0.926,1.06 932 9300 0.7447 0.989 0.924,1.06 909 9156
567 Peritonitis and retroperitoneal infections digestive Both 0.2965 0.968 0.911,1.03 1149 11482 0.166 0.957 0.899,1.02 1115 11332
568 Other disorders of peritoneum digestive Both 0.9057 0.997 0.944,1.05 1452 14494 0.9141 0.997 0.936,1.06 1056 10608
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.8017 1.01 0.947,1.07 1076 10752 0.9141 0.997 0.936,1.06 1056 10608
569 Other disorders of intestine digestive Both 0.1849 0.982 0.955,1.01 6343 29512 0.2133 0.963 0.906,1.02 1181 11889
569.1 Toxic gastroenteritis and colitis digestive Both 0.2742 1.08 0.943,1.23 251 2510 0.3027 1.08 0.937,1.23 230 2471
569.2 Gastrointestinal complications digestive Both 0.3639 0.973 0.917,1.03 1206 12058 0.2133 0.963 0.906,1.02 1181 11889
571 Chronic liver disease and cirrhosis digestive Both 0.1183 0.973 0.939,1.01 3603 27394 0.1324 0.926 0.838,1.02 425 4351
571.5 Other chronic nonalcoholic liver disease digestive Both 0.1472 0.974 0.939,1.01 3388 27100 0.4074 0.969 0.899,1.04 752 7720
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.5957 0.98 0.911,1.05 781 7802 0.4074 0.969 0.899,1.04 752 7720
571.6 Primary biliary cirrhosis digestive Both 0.0912 0.863 0.727,1.02 146 1460 0.1059 0.867 0.729,1.03 142 1443
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.08913 0.937 0.87,1.01 749 7472 0.1324 0.926 0.838,1.02 425 4351
571.81 Portal hypertension digestive Both 0.2692 0.946 0.858,1.04 441 4400 0.1324 0.926 0.838,1.02 425 4351
572 Ascites (non malignant) digestive Both 0.2443 0.972 0.927,1.02 1884 18805 0.1096 0.961 0.916,1.01 1815 18609
573 Other disorders of liver digestive Both 0.1995 0.979 0.949,1.01 4460 28151 0.3524 1.02 0.981,1.06 3216 27769
573.1 Chronic passive congestion of liver digestive Both 0.2985 0.897 0.731,1.1 100 991 0.4236 0.919 0.748,1.13 97 977
573.2 Liver replaced by transplant digestive Both 0.4345 0.947 0.828,1.08 227 2268 0.4375 0.946 0.823,1.09 213 2242
573.3 Hepatomegaly digestive Both 0.8872 0.992 0.887,1.11 337 3368 0.7244 0.98 0.874,1.1 324 3334
573.4 Acute and subacute necrosis of liver digestive Both 0.1742 0.915 0.805,1.04 258 2580 0.1191 0.901 0.79,1.03 246 2557
573.5 Jaundice (not of newborn) digestive Both 0.2951 0.961 0.891,1.04 758 7555 0.2046 0.952 0.881,1.03 718 7462
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.9057 0.997 0.952,1.04 1973 19683 0.8551 0.996 0.95,1.04 1882 19470
573.7 Abnormal results of function study of liver digestive Both 0.2046 0.971 0.929,1.02 2110 21014 0.1552 0.967 0.924,1.01 2037 20793
573.9 Abnormal serum enzyme levels digestive Both 0.2163 1.02 0.987,1.06 3345 28043 0.3524 1.02 0.981,1.06 3216 27769
574 Cholelithiasis and cholecystitis digestive Both 0.4656 1.02 0.975,1.06 2610 25589 0.009772 1.11 1.03,1.2 649 6580
574.1 Cholelithiasis digestive Both 0.5272 1.01 0.972,1.06 2391 23829 0.3097 1.05 0.954,1.16 441 4379
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.03981 1.14 1.01,1.29 260 2580 0.05623 1.13 0.997,1.28 254 2549
574.12 Cholelithiasis with other cholecystitis digestive Both 0.2754 1.06 0.958,1.16 444 4434 0.3097 1.05 0.954,1.16 441 4379
574.2 Calculus of bile duct digestive Both 0.7691 1.01 0.936,1.09 696 6939 0.8147 1.01 0.933,1.09 680 6858
574.3 Cholecystitis without cholelithiasis digestive Both 0.01072 1.11 1.02,1.2 667 6662 0.009772 1.11 1.03,1.2 649 6580
575 Other biliary tract disease digestive Both 0.7015 0.991 0.945,1.04 1868 18668 0.9183 0.992 0.854,1.15 184 1851
575.1 Cholangitis digestive Both 0.4395 0.955 0.851,1.07 310 3089 0.3828 0.949 0.844,1.07 302 3021
575.2 Obstruction of bile duct digestive Both 0.0631 0.919 0.841,1.0 530 5291 0.05495 0.916 0.837,1.0 518 5213
575.6 Cholesterolosis of gallbladder digestive Both 0.9908 0.999 0.855,1.17 168 1680 0.7396 0.973 0.831,1.14 162 1668
575.7 Other disorders of gallbladder digestive Both 0.537 1.02 0.951,1.1 773 7719 0.5309 1.02 0.951,1.1 758 7620
575.8 Other disorders of biliary tract digestive Both 0.3228 0.968 0.907,1.03 996 9950 0.2506 0.962 0.901,1.03 972 9799
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.6982 0.971 0.837,1.13 188 1880 0.9183 0.992 0.854,1.15 184 1851
577 Diseases of pancreas digestive Both 0.03802 0.95 0.906,0.997 1842 18379 0.2576 0.945 0.857,1.04 447 4460
577.1 Acute pancreatitis digestive Both 0.1164 0.948 0.888,1.01 967 9651 0.06918 0.94 0.879,1.0 940 9499
577.2 Chronic pancreatitis digestive Both 0.9419 1.0 0.906,1.11 396 3955 0.8375 0.989 0.891,1.1 381 3901
577.3 Cyst and pseudocyst of pancreas digestive Both 0.4426 0.963 0.875,1.06 462 4557 0.2576 0.945 0.857,1.04 447 4460
578 Gastrointestinal hemorrhage digestive Both 0.8241 0.996 0.962,1.03 3572 30460 0.2312 0.964 0.908,1.02 1176 12125
578.1 Hematemesis digestive Both 0.07943 1.1 0.989,1.22 383 3821 0.1014 1.09 0.983,1.21 372 3780
578.2 Blood in stool digestive Both 0.8974 1.0 0.96,1.05 2156 21196 0.9183 1.0 0.958,1.05 2085 20938
578.8 Hemorrhage of rectum and anus digestive Both 0.5808 0.986 0.938,1.04 1718 17070 0.4385 0.98 0.932,1.03 1672 16887
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.2535 0.967 0.912,1.02 1238 12280 0.2312 0.964 0.908,1.02 1176 12125
579 Other symptoms involving abdomen and pelvis digestive Both 0.05754 0.967 0.935,1.0 3750 28690 0.743 1.01 0.946,1.08 959 9748
579.2 Splenomegaly digestive Both 0.008128 0.891 0.818,0.97 593 5923 0.002818 0.872 0.797,0.954 538 5866
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.8072 1.01 0.945,1.08 998 9882 0.743 1.01 0.946,1.08 959 9748
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.975 0.999 0.943,1.06 1264 12626 0.05495 1.13 0.997,1.29 262 2717
580.1 Glomerulonephritis genitourinary Both 1.0 1.0 0.889,1.13 324 3228 0.861 0.987 0.858,1.14 222 2274
580.11 Proliferative glomerulonephritis genitourinary Both 0.811 1.02 0.845,1.24 114 1140 0.798 1.03 0.843,1.25 108 1129
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.3846 1.1 0.89,1.36 92 905 0.399 1.1 0.885,1.36 87 898
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.7516 0.978 0.851,1.12 232 2298 0.861 0.987 0.858,1.14 222 2274
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.6223 0.961 0.819,1.13 167 1670 0.6887 0.967 0.822,1.14 159 1655
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.3954 0.971 0.908,1.04 943 9430 0.3972 0.959 0.871,1.06 467 4935
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.5483 0.974 0.892,1.06 554 5535 0.5916 0.976 0.893,1.07 532 5473
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.4446 0.964 0.879,1.06 500 4995 0.3972 0.959 0.871,1.06 467 4935
580.4 Renal sclerosis, NOS genitourinary Both 0.07244 1.12 0.99,1.27 275 2750 0.05495 1.13 0.997,1.29 262 2717
585 Renal failure genitourinary Both 0.3459 1.01 0.985,1.04 5756 27307 0.4345 1.03 0.958,1.11 809 8282
585.1 Acute renal failure genitourinary Both 0.228 1.02 0.986,1.06 3278 22851 0.3811 1.02 0.979,1.06 3127 22635
585.2 Renal failure NOS genitourinary Both 0.06026 1.08 0.997,1.16 688 6872 0.0912 1.07 0.989,1.16 644 6783
585.3 Chronic renal failure [CKD] genitourinary Both 0.8933 0.998 0.965,1.03 4216 24655 0.3083 1.04 0.963,1.13 672 6956
585.31 Renal dialysis genitourinary Both 0.9528 0.997 0.913,1.09 543 5430 0.9141 0.995 0.909,1.09 517 5370
585.32 End stage renal disease genitourinary Both 0.9886 1.0 0.929,1.08 773 7730 0.9908 1.0 0.928,1.08 741 7645
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.4519 0.983 0.941,1.03 2272 17155 0.3483 0.979 0.935,1.02 2170 16975
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.4477 1.03 0.954,1.11 707 7038 0.3083 1.04 0.963,1.13 672 6956
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.342 1.03 0.964,1.11 851 8381 0.4345 1.03 0.958,1.11 809 8282
586 Other disorders of the kidney and ureters genitourinary Both 0.6471 1.01 0.979,1.04 6202 28774 0.5383 0.983 0.933,1.04 1505 14517
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.02138 1.15 1.02,1.3 284 2825 0.3459 1.1 0.905,1.33 111 1110
586.11 Small kidney genitourinary Both 0.02188 1.2 1.03,1.4 165 1642 0.01122 1.22 1.05,1.43 158 1627
586.12 Vesicoureteral reflux genitourinary Both 0.2965 1.11 0.914,1.34 112 1120 0.3459 1.1 0.905,1.33 111 1110
586.2 Cyst of kidney, acquired genitourinary Both 0.5188 1.02 0.961,1.08 1170 11069 0.5495 1.02 0.958,1.08 1118 10929
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.9099 1.01 0.852,1.2 148 1470 0.8185 1.02 0.859,1.21 145 1454
586.4 Stricture/obstruction of ureter genitourinary Both 0.6166 0.987 0.936,1.04 1536 14675 0.5383 0.983 0.933,1.04 1505 14517
587 Kidney replaced by transpant genitourinary Both 0.2723 1.05 0.964,1.14 612 6120 0.542 1.03 0.944,1.12 589 6065
588 Disorders resulting from impaired renal function genitourinary Both 0.6918 0.984 0.911,1.06 701 7004 0.369 1.04 0.952,1.14 502 5187
588.1 Renal osteodystrophy genitourinary Both 0.7925 0.982 0.856,1.13 227 2267 0.7345 0.976 0.849,1.12 217 2244
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.4246 1.04 0.949,1.13 525 5241 0.369 1.04 0.952,1.14 502 5187
589 Abnormal results of function study of kidney genitourinary Both 0.5702 1.02 0.951,1.1 840 8370 0.6745 1.02 0.944,1.09 798 8273
590 Pyelonephritis genitourinary Both 0.2084 1.04 0.979,1.1 1161 11597 0.2249 1.04 0.977,1.1 1130 11472
591 Urinary tract infection genitourinary Both 0.1361 0.981 0.956,1.01 8020 27291 0.09772 0.978 0.954,1.0 7830 26978
592 Cystitis and urethritis genitourinary Both 0.6166 0.989 0.946,1.03 2264 19423 0.5093 0.942 0.79,1.12 141 1417
592.1 Cystitis genitourinary Both 0.5781 0.987 0.944,1.03 2149 18531 0.4656 0.96 0.859,1.07 348 3514
592.11 Acute cystitis genitourinary Both 0.8356 0.994 0.937,1.05 1256 12111 0.6138 0.985 0.927,1.05 1205 11968
592.12 Chronic cystitis genitourinary Both 0.8222 1.02 0.879,1.18 199 1972 0.9638 1.0 0.866,1.16 195 1953
592.13 Chronic interstitial cystitis genitourinary Both 0.6012 0.971 0.87,1.08 354 3540 0.4656 0.96 0.859,1.07 348 3514
592.2 Urethritis and urethral syndrome genitourinary Both 0.4842 0.939 0.788,1.12 143 1430 0.5093 0.942 0.79,1.12 141 1417
593 Hematuria genitourinary Both 0.2871 0.982 0.949,1.02 3848 26566 0.2999 0.959 0.887,1.04 705 7142
593.1 Gross hematuria genitourinary Both 0.9572 0.998 0.94,1.06 1201 11351 0.778 0.991 0.933,1.05 1159 11162
593.2 Microscopic hematuria genitourinary Both 0.4656 0.972 0.899,1.05 724 7225 0.2999 0.959 0.887,1.04 705 7142
594 Urinary calculus genitourinary Both 0.4508 1.01 0.982,1.04 5516 31876 0.8147 0.985 0.871,1.11 279 2826
594.1 Calculus of kidney genitourinary Both 0.4764 1.01 0.981,1.04 5155 31730 0.5649 1.01 0.979,1.04 5051 31320
594.2 Calculus of lower urinary tract genitourinary Both 0.526 0.963 0.855,1.08 310 3068 0.3981 0.949 0.842,1.07 300 2999
594.3 Calculus of ureter genitourinary Both 0.1549 1.05 0.983,1.11 1104 11000 0.2133 1.04 0.978,1.11 1076 10840
594.8 Renal colic genitourinary Both 0.9441 0.996 0.882,1.12 286 2851 0.8147 0.985 0.871,1.11 279 2826
595 Hydronephrosis genitourinary Both 0.7852 0.992 0.94,1.05 1410 14092 0.7228 0.99 0.937,1.05 1372 13875
596 Other disorders of bladder genitourinary Both 0.7228 1.01 0.967,1.05 2527 23338 0.9078 0.997 0.942,1.05 1329 13409
596.1 Bladder neck obstruction genitourinary Both 0.9099 0.994 0.888,1.11 333 3288 0.9484 0.996 0.889,1.12 327 3201
596.5 Functional disorders of bladder genitourinary Both 0.8017 1.01 0.953,1.06 1368 13608 0.9078 0.997 0.942,1.05 1329 13409
597 Other disorders of urethra and urinary tract genitourinary Both 0.6427 0.985 0.924,1.05 1041 10322 0.3334 0.92 0.777,1.09 155 1562
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.8241 0.991 0.911,1.08 608 6024 0.7907 0.989 0.908,1.08 592 5898
597.2 Urinary complications NEC genitourinary Both 0.9247 1.0 0.936,1.08 861 8600 0.7586 1.01 0.942,1.08 846 8480
597.8 Urethral hypermobility/ISD genitourinary Both 0.4285 0.935 0.791,1.11 158 1578 0.3334 0.92 0.777,1.09 155 1562
598 Abnormal findings on examination of urine genitourinary Both 0.9162 0.997 0.941,1.06 1263 12596 0.929 0.997 0.939,1.06 1183 12117
598.4 Other cells and casts in urine genitourinary Both 0.826 1.02 0.823,1.28 91 906 0.9311 1.01 0.809,1.26 88 889
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.8974 0.996 0.939,1.06 1234 12317 0.929 0.997 0.939,1.06 1183 12117
599 Other symptoms/disorders or the urinary system genitourinary Both 0.1875 0.985 0.963,1.01 11346 25364 0.6026 0.988 0.946,1.03 2285 20055
599.1 Urinary obstruction genitourinary Both 0.869 0.993 0.911,1.08 580 5634 0.7499 0.986 0.903,1.08 564 5535
599.2 Retention of urine genitourinary Both 0.2838 0.982 0.95,1.02 4234 24058 0.1986 0.978 0.945,1.01 4123 23805
599.3 Dysuria genitourinary Both 0.01698 0.957 0.922,0.992 3426 23180 0.007413 0.951 0.916,0.987 3332 22934
599.4 Urinary incontinence genitourinary Both 0.3148 0.983 0.952,1.02 4566 22567 0.1959 0.979 0.947,1.01 4477 22321
599.5 Frequency of urination and polyuria genitourinary Both 0.9638 1.0 0.968,1.03 4277 23742 0.8337 0.996 0.964,1.03 4169 23488
599.6 Oliguria and anuria genitourinary Both 0.8128 0.989 0.904,1.08 513 5104 0.6998 0.982 0.897,1.08 498 5035
599.7 Urethral discharge genitourinary Both 0.0912 1.21 0.97,1.51 83 830 0.0871 1.22 0.971,1.53 79 816
599.8 Other symptoms involving urinary system genitourinary Both 0.02951 0.964 0.933,0.996 4366 23262 0.01622 0.96 0.928,0.992 4270 23009
599.9 Other abnormality of urination genitourinary Both 0.6457 0.99 0.948,1.03 2349 20289 0.6026 0.988 0.946,1.03 2285 20055
600 Hyperplasia of prostate genitourinary Male 0.507 0.986 0.945,1.03 3315 9437 0.3451 0.98 0.939,1.02 3201 9296
601 Inflammatory diseases of prostate genitourinary Male 0.547 1.02 0.952,1.1 825 7745 0.06918 1.18 0.987,1.41 116 1205
601.1 Prostatitis genitourinary Male 0.5297 1.03 0.932,1.15 378 3680 0.3606 1.11 0.885,1.4 73 737
601.11 Acute prostatitis genitourinary Male 0.1742 1.15 0.94,1.41 95 933 0.1315 1.17 0.953,1.44 91 908
601.12 Chronic prostatitis genitourinary Male 0.5333 1.07 0.858,1.34 76 757 0.3606 1.11 0.885,1.4 73 737
601.3 Orchitis and epididymitis genitourinary Male 0.778 0.983 0.874,1.11 303 3008 0.9183 0.994 0.881,1.12 292 2964
601.4 Balanoposthitis genitourinary Male 0.9886 0.998 0.818,1.22 103 1019 0.9484 1.01 0.824,1.23 103 1003
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.06166 1.18 0.992,1.4 125 1226 0.06918 1.18 0.987,1.41 116 1205
602 Other disorders of prostate genitourinary Male 0.881 0.991 0.877,1.12 277 2673 0.8913 0.991 0.875,1.12 267 2618
603 Other disorders of testis genitourinary Male 0.1371 0.92 0.824,1.03 348 3468 0.8974 0.988 0.817,1.19 125 1237
603.1 Hydrocele genitourinary Male 0.4898 0.954 0.835,1.09 229 2281 0.5458 0.959 0.838,1.1 223 2241
603.2 Spermatocele genitourinary Male 0.8851 0.986 0.817,1.19 126 1258 0.8974 0.988 0.817,1.19 125 1237
604 Disorders of penis genitourinary Male 0.4645 0.967 0.884,1.06 536 5321 0.6471 0.964 0.823,1.13 167 1682
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.2911 1.1 0.919,1.33 130 1297 0.25 1.12 0.926,1.35 125 1264
604.3 Peyronie's disease genitourinary Male 0.7534 0.975 0.835,1.14 171 1703 0.6471 0.964 0.823,1.13 167 1682
605 Erectile dysfunction [ED] genitourinary Male 0.2265 0.974 0.934,1.02 2844 10666 0.1807 0.971 0.931,1.01 2782 10511
608 Other disorders of male genital organs genitourinary Male 0.9817 0.999 0.944,1.06 1302 11530 0.9661 0.999 0.942,1.06 1272 11373
609 Male infertility and abnormal spermatozoa genitourinary Male 0.3342 1.06 0.946,1.18 335 3350 0.7691 1.03 0.854,1.24 117 1162
609.1 Infertility, male genitourinary Male 0.3076 1.07 0.94,1.22 242 2420 0.6823 1.05 0.841,1.3 79 787
609.11 Azoospermia and oligospermia genitourinary Male 0.695 1.04 0.839,1.3 79 789 0.6823 1.05 0.841,1.3 79 787
609.2 Abnormal spermatozoa genitourinary Male 0.7925 1.02 0.853,1.23 119 1185 0.7691 1.03 0.854,1.24 117 1162
610 Benign mammary dysplasias genitourinary Female 0.1585 1.03 0.989,1.07 3089 13905 0.1517 1.05 0.983,1.12 1025 10048
610.1 Cystic mastopathy genitourinary Female 0.3664 1.03 0.97,1.09 1361 12011 0.3119 1.03 0.973,1.09 1332 11892
610.4 Benign neoplasm of breast genitourinary Female 0.06761 1.04 0.997,1.09 2400 13828 0.04898 1.05 1.0,1.09 2361 13699
610.8 Other specified benign mammary dysplasias genitourinary Female 0.1667 1.05 0.981,1.12 1047 10149 0.1517 1.05 0.983,1.12 1025 10048
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.08511 1.03 0.996,1.06 4952 15509 0.7396 1.01 0.967,1.05 2953 15295
611.1 Abnormal mammogram genitourinary Both 0.2065 1.02 0.987,1.06 4074 13538 0.6026 1.02 0.951,1.09 938 9031
611.11 Mammographic microcalcification genitourinary Both 0.6353 1.02 0.95,1.09 962 9131 0.6026 1.02 0.951,1.09 938 9031
611.3 Lump or mass in breast genitourinary Both 0.778 1.01 0.967,1.05 3011 15449 0.7396 1.01 0.967,1.05 2953 15295
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.0912 1.06 0.99,1.14 879 8768 0.4477 1.03 0.952,1.12 661 6637
612.1 Galactorrhea genitourinary Both 0.1178 1.17 0.961,1.43 109 1083 0.1057 1.18 0.966,1.44 106 1073
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.4732 1.03 0.95,1.12 672 6710 0.4477 1.03 0.952,1.12 661 6637
612.3 Congenital anomalies of breast genitourinary Both 0.1535 1.19 0.937,1.51 70 676 ,
613 Other nonmalignant breast conditions genitourinary Both 0.6902 1.01 0.97,1.05 3180 18154 0.8222 0.993 0.935,1.05 1180 11811
613.1 Inflammatory disease of breast genitourinary Both 0.3112 1.05 0.957,1.15 504 5035 0.3373 1.05 0.954,1.15 497 4984
613.5 Mastodynia genitourinary Both 0.06918 1.05 0.996,1.12 1313 12942 0.07762 1.05 0.994,1.12 1279 12795
613.7 Other signs and symptoms in breast genitourinary Both 0.3221 1.04 0.963,1.12 722 7109 0.3069 1.04 0.963,1.13 709 7035
613.8 Other specified disorders of breast genitourinary Both 0.7816 0.99 0.92,1.07 800 7961 0.8433 0.993 0.922,1.07 789 7882
613.9 Breast disorder NOS genitourinary Both 0.7603 0.991 0.933,1.05 1211 11947 0.8222 0.993 0.935,1.05 1180 11811
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.1426 1.03 0.99,1.07 2990 16271 0.5458 1.05 0.896,1.23 163 1602
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.6138 1.03 0.911,1.17 267 2670 0.5794 1.04 0.913,1.18 261 2648
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.7834 1.01 0.915,1.13 404 4024 0.3784 1.07 0.923,1.23 197 1960
614.31 Acute inflammatory pelvic disease genitourinary Female 0.5702 0.935 0.74,1.18 74 720 0.5741 0.935 0.741,1.18 74 715
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.7311 0.972 0.826,1.14 167 1666 0.6353 0.961 0.816,1.13 164 1649
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.414 1.06 0.919,1.23 198 1979 0.3784 1.07 0.923,1.23 197 1960
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.8414 0.982 0.823,1.17 129 1290 0.7998 0.977 0.817,1.17 126 1285
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.1297 1.03 0.99,1.08 2546 16112 0.5458 1.05 0.896,1.23 163 1602
614.51 Cervicitis and endocervicitis genitourinary Female 0.5058 0.951 0.821,1.1 197 1970 0.5188 0.952 0.821,1.1 194 1948
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.1466 1.03 0.988,1.08 2201 15690 0.1694 1.03 0.987,1.08 2160 15535
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.3258 1.1 0.908,1.34 104 1040 0.3327 1.1 0.907,1.33 104 1032
614.54 Abscess or ulceration of vulva genitourinary Female 0.5984 1.04 0.89,1.22 164 1619 0.5458 1.05 0.896,1.23 163 1602
615 Endometriosis genitourinary Female 0.9376 1.0 0.946,1.06 1298 12230 0.984 0.999 0.943,1.06 1290 12123
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.9908 1.0 0.947,1.06 1415 13522 0.8128 0.993 0.94,1.05 1391 13380
618 Genital prolapse genitourinary Female 0.2004 0.967 0.92,1.02 1707 14626 0.4436 0.959 0.861,1.07 374 3704
618.1 Prolapse of vaginal walls genitourinary Female 0.04898 0.941 0.885,1.0 1179 11187 0.03548 0.936 0.881,0.996 1167 11049
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.9099 1.01 0.912,1.11 444 4418 0.8933 1.01 0.913,1.11 441 4363
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.7482 0.981 0.87,1.1 286 2855 0.7345 0.98 0.869,1.1 285 2816
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.4406 0.959 0.861,1.07 375 3750 0.4436 0.959 0.861,1.07 374 3704
619 Noninflammatory female genital disorders genitourinary Female 0.912 1.0 0.969,1.04 4598 15534 0.3214 0.965 0.901,1.03 898 8991
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.5957 0.984 0.928,1.04 1262 11294 0.6561 0.987 0.93,1.05 1247 11193
619.2 Disorders of uterus, NEC genitourinary Female 0.492 0.966 0.876,1.07 444 4435 0.6124 0.975 0.883,1.08 437 4396
619.3 Noninflammatory disorders of cervix genitourinary Female 0.3715 0.953 0.858,1.06 391 3892 0.3357 0.949 0.854,1.06 386 3857
619.4 Noninflammatory disorders of vagina genitourinary Female 0.5534 1.01 0.967,1.06 1903 15019 0.6324 1.01 0.964,1.06 1868 14867
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.3251 0.966 0.902,1.03 914 9082 0.3214 0.965 0.901,1.03 898 8991
620 Dysplasia of female genital organs genitourinary Female 0.6622 1.03 0.914,1.15 325 3234 0.9333 1.01 0.848,1.2 140 1409
620.1 Dysplasia of cervix genitourinary Female 0.9572 1.0 0.846,1.19 142 1420 0.9333 1.01 0.848,1.2 140 1409
621 Endometrial hyperplasia genitourinary Female 0.05623 0.896 0.801,1.0 334 3335 0.0389 0.888 0.793,0.994 330 3302
622 Polyp of female genital organs genitourinary Female 0.0955 0.95 0.894,1.01 1191 11723 0.5224 0.964 0.863,1.08 345 3442
622.1 Polyp of corpus uteri genitourinary Female 0.1393 0.951 0.889,1.02 949 9362 0.1368 0.95 0.888,1.02 934 9259
622.2 Mucous polyp of cervix genitourinary Female 0.4634 0.96 0.859,1.07 348 3480 0.5224 0.964 0.863,1.08 345 3442
623 Hypertrophy of female genital organs genitourinary Female 0.7396 1.01 0.933,1.1 605 6003 0.8185 1.01 0.928,1.1 596 5939
624 Symptoms involving female genital tract genitourinary Female 0.3467 0.969 0.908,1.03 1013 9695 0.01096 0.933 0.884,0.984 1537 12783
624.1 Dystrophy of female genital tract genitourinary Female 0.3758 1.07 0.919,1.25 168 1680 0.4227 1.07 0.913,1.24 165 1659
624.9 stress incontinence, female genitourinary Female 0.01096 0.933 0.884,0.984 1549 12918 0.01096 0.933 0.884,0.984 1537 12783
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.2056 0.979 0.946,1.01 4618 14394 0.0871 0.945 0.885,1.01 1005 9990
625.1 Dyspareunia genitourinary Female 0.104 0.947 0.888,1.01 1011 10081 0.0871 0.945 0.885,1.01 1005 9990
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.1919 0.977 0.944,1.01 4726 13065 0.2723 0.954 0.876,1.04 620 5185
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.5675 0.989 0.951,1.03 3426 12112 0.3192 0.941 0.835,1.06 297 2978
626.11 Absent or infrequent menstruation genitourinary Female 0.08511 0.937 0.87,1.01 802 6948 0.1288 0.944 0.876,1.02 788 6902
626.12 Excessive or frequent menstruation genitourinary Female 0.5875 0.986 0.936,1.04 1703 9843 0.631 0.987 0.937,1.04 1681 9767
626.13 Irregular menstrual cycle genitourinary Female 0.9638 1.0 0.948,1.06 1543 10197 0.8414 1.01 0.952,1.06 1525 10114
626.14 Irregular menstrual bleeding genitourinary Female 0.4188 1.03 0.957,1.11 777 7408 0.354 1.04 0.961,1.12 763 7358
626.15 Infertility, female, associated with anovulation genitourinary Female 0.3436 0.944 0.838,1.06 300 3000 0.3192 0.941 0.835,1.06 297 2978
626.2 Dysmenorrhea genitourinary Female 0.1104 0.95 0.891,1.01 1116 8297 0.1148 0.95 0.891,1.01 1106 8240
626.4 Premenstrual tension syndromes genitourinary Female 0.3475 0.941 0.829,1.07 275 2741 0.3606 0.942 0.829,1.07 270 2720
626.8 Infertility, female genitourinary Female 0.2767 0.954 0.877,1.04 630 5218 0.2723 0.954 0.876,1.04 620 5185
627 Menopausal and postmenopausal disorders genitourinary Female 0.4487 0.986 0.949,1.02 3657 12296 0.2028 1.09 0.954,1.25 228 2319
627.1 Postmenopausal bleeding genitourinary Female 0.4853 0.976 0.912,1.04 957 8768 0.5284 0.978 0.914,1.05 942 8667
627.2 Symptomatic menopause genitourinary Female 0.7328 0.992 0.949,1.04 2443 11667 0.1153 1.1 0.976,1.25 289 2912
627.21 Symptomatic artificial menopause genitourinary Female 0.26 0.897 0.742,1.08 125 1241 0.2432 0.892 0.735,1.08 120 1232
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.1227 1.1 0.975,1.24 295 2948 0.1153 1.1 0.976,1.25 289 2912
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.3758 0.966 0.894,1.04 729 7262 0.4236 0.969 0.896,1.05 712 7171
627.4 Premenopausal menorrhagia genitourinary Female 0.7516 1.02 0.904,1.15 305 3020 0.7499 1.02 0.904,1.15 304 2992
627.5 Premature menopause and other ovarian failure genitourinary Female 0.2891 1.07 0.941,1.23 234 2340 0.2028 1.09 0.954,1.25 228 2319
628 Ovarian cyst genitourinary Female 0.7534 0.992 0.941,1.05 1619 11554 0.7568 0.992 0.94,1.05 1597 11451
634 Miscarriage; stillbirth pregnancy complications Female 0.857 0.992 0.915,1.08 648 6413 0.1914 0.871 0.707,1.07 93 939
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.2541 1.09 0.942,1.25 209 2090 0.3133 1.08 0.933,1.24 205 2081
634.3 Ectopic pregnancy pregnancy complications Female 0.1995 0.874 0.711,1.07 95 950 0.1914 0.871 0.707,1.07 93 939
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.0955 0.916 0.827,1.02 414 4070 0.118 0.889 0.767,1.03 204 2049
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.2109 0.923 0.813,1.05 272 2720 0.1845 0.918 0.808,1.04 269 2709
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.1167 0.889 0.768,1.03 206 2060 0.118 0.889 0.767,1.03 204 2049
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.7551 0.989 0.92,1.06 855 6402 0.06761 0.771 0.584,1.02 60 599
636.1 Threatened premature labor pregnancy complications Female 0.2328 0.929 0.824,1.05 298 2980 0.2312 0.929 0.823,1.05 295 2965
636.2 Early onset of delivery pregnancy complications Female 0.2799 0.927 0.809,1.06 233 2330 0.2742 0.926 0.807,1.06 228 2322
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.5508 1.03 0.927,1.15 356 3556 0.5848 1.03 0.924,1.15 351 3535
636.8 Cervical incompetence pregnancy complications Female 0.06761 0.771 0.584,1.02 60 600 0.06761 0.771 0.584,1.02 60 599
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.3999 0.908 0.724,1.14 89 884 0.5105 0.926 0.737,1.16 87 866
638 Other high-risk pregnancy pregnancy complications Female 0.9572 0.998 0.927,1.07 818 5867 0.9204 0.996 0.925,1.07 808 5832
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.2234 0.938 0.847,1.04 421 4210 0.06607 0.872 0.754,1.01 211 2131
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.06761 0.874 0.756,1.01 215 2150 0.06607 0.872 0.754,1.01 211 2131
643 Excessive vomiting in pregnancy pregnancy complications Female 0.2009 1.1 0.949,1.28 181 1810 0.0302 1.28 1.02,1.59 82 865
643.1 Hyperemesis gravidarum pregnancy complications Female 0.03311 1.26 1.02,1.57 87 870 0.0302 1.28 1.02,1.59 82 865
644 Anemia during pregnancy pregnancy complications Female 0.7516 0.973 0.824,1.15 154 1540 0.7063 0.968 0.818,1.15 149 1532
645 Late pregnancy and failed induction pregnancy complications Female 0.7499 0.98 0.867,1.11 286 2860 0.7889 0.983 0.87,1.11 284 2843
646 Other complications of pregnancy NEC pregnancy complications Female 0.1211 1.07 0.983,1.16 622 5063 0.1459 1.06 0.978,1.16 613 5034
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.9506 1.01 0.847,1.19 152 1520 0.2404 1.1 0.939,1.28 180 1811
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.2198 1.1 0.944,1.29 182 1820 0.2404 1.1 0.939,1.28 180 1811
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.6252 0.983 0.918,1.05 968 6387 0.4775 0.963 0.869,1.07 408 4110
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.4295 0.96 0.866,1.06 413 4130 0.4775 0.963 0.869,1.07 408 4110
650 Normal delivery pregnancy complications Female 0.8054 0.99 0.918,1.07 757 6412 0.7762 0.989 0.916,1.07 748 6374
651 Multiple gestation pregnancy complications Female 0.005888 0.737 0.593,0.916 100 1000 0.006457 0.74 0.595,0.919 100 992
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.1871 0.937 0.85,1.03 461 4586 0.1991 0.938 0.852,1.03 459 4555
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.9099 0.994 0.9,1.1 443 4189 0.867 0.992 0.898,1.1 440 4162
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.875 0.993 0.903,1.09 482 4820 0.3524 0.926 0.788,1.09 162 1614
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.3565 0.952 0.858,1.06 402 4020 0.3516 0.952 0.857,1.06 399 3994
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.3899 0.932 0.792,1.1 163 1630 0.3524 0.926 0.788,1.09 162 1614
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.5998 0.984 0.926,1.05 1244 8117 0.7852 1.01 0.92,1.12 449 4342
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.811 1.01 0.918,1.12 451 4371 0.7852 1.01 0.92,1.12 449 4342
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.5483 1.04 0.912,1.19 246 2460 0.4074 1.12 0.858,1.46 59 583
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.4074 1.12 0.858,1.46 59 590 0.4074 1.12 0.858,1.46 59 583
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.6152 1.04 0.896,1.2 195 1950 0.5689 1.04 0.9,1.21 192 1933
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.4457 0.965 0.879,1.06 504 4732 0.4645 0.966 0.88,1.06 497 4699
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.1256 0.923 0.833,1.02 420 4080 0.1148 0.92 0.83,1.02 418 4056
665 Obstetrical/birth trauma pregnancy complications Female 0.5129 0.975 0.903,1.05 751 6161 0.4732 0.972 0.9,1.05 744 6121
669 Complications of labor and delivery NEC pregnancy complications Female 0.4603 0.97 0.894,1.05 671 5265 0.4592 0.97 0.893,1.05 664 5225
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.1722 0.893 0.76,1.05 172 1720 0.1528 0.886 0.751,1.05 165 1713
674 Other complications of the puerperium NEC pregnancy complications Female 0.02951 0.841 0.719,0.983 181 1810 0.0302 0.841 0.719,0.983 181 1797
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.6252 1.05 0.87,1.26 122 1220 0.6714 1.04 0.864,1.25 121 1216
681 Superficial cellulitis and abscess dermatologic Both 0.3342 1.01 0.985,1.05 5078 31991 0.9141 0.997 0.939,1.06 1200 12206
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.5445 1.02 0.953,1.1 862 8581 0.7047 1.01 0.944,1.09 824 8475
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.2818 1.04 0.967,1.12 781 7775 0.4375 1.03 0.956,1.11 755 7683
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.8091 1.01 0.955,1.06 1533 15238 0.9977 1.0 0.948,1.06 1471 15046
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.2897 1.03 0.977,1.08 1649 16359 0.3412 1.03 0.974,1.08 1579 16155
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.2523 1.03 0.977,1.09 1291 12850 0.3396 1.03 0.971,1.09 1238 12682
681.7 Cellulitis and abscess of trunk dermatologic Both 0.879 0.995 0.939,1.06 1238 12342 0.9141 0.997 0.939,1.06 1200 12206
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.7852 0.993 0.944,1.04 1660 16466 0.6531 1.04 0.865,1.26 118 1192
686.1 Carbuncle and furuncle dermatologic Both 0.8318 0.989 0.892,1.1 390 3881 0.8974 0.993 0.895,1.1 380 3833
686.2 Impetigo dermatologic Both 0.9506 1.0 0.893,1.13 310 3068 0.8395 1.01 0.899,1.14 299 3037
686.3 Pilonidal cyst dermatologic Both 0.3597 0.916 0.759,1.11 120 1200 0.3811 0.919 0.762,1.11 120 1188
686.4 Pyogenic granuloma dermatologic Both 0.5998 1.05 0.873,1.27 121 1205 0.6531 1.04 0.865,1.26 118 1192
687 Symptoms affecting skin dermatologic Both 0.1462 1.02 0.993,1.05 6119 25901 0.3467 1.01 0.984,1.05 4835 25342
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.5902 1.01 0.979,1.04 5371 25824 0.7228 1.01 0.976,1.04 5213 25581
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.6855 1.01 0.977,1.04 5264 25870 0.8453 1.0 0.973,1.03 5106 25625
687.3 Changes in skin texture dermatologic Both 0.06026 1.12 0.995,1.26 294 2926 0.08511 1.11 0.986,1.25 286 2895
687.4 Disturbance of skin sensation dermatologic Both 0.2864 1.02 0.986,1.05 4942 25586 0.3467 1.01 0.984,1.05 4835 25342
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.07586 1.02 0.998,1.05 7192 31086 0.1297 1.02 0.994,1.05 7005 30728
690 Erythematosquamous dermatosis dermatologic Both 0.006607 1.05 1.01,1.09 3810 26256 0.01445 1.04 1.01,1.08 3696 25882
690.1 Seborrheic dermatitis dermatologic Both 0.00631 1.05 1.01,1.09 3802 26218 0.01445 1.04 1.01,1.08 3696 25882
691 Congenital anomalies of skin dermatologic Both 0.1507 1.08 0.974,1.19 411 4110 0.08511 1.09 0.988,1.21 399 4056
694 Dyschromia and Vitiligo dermatologic Both 0.0537 1.06 0.999,1.12 1286 12819 0.7852 1.03 0.812,1.32 67 683
694.1 Vitiligo dermatologic Both 0.8851 0.985 0.805,1.21 94 931 0.857 0.981 0.799,1.21 91 921
694.2 Other dyschromia dermatologic Both 0.0955 1.05 0.991,1.12 1146 11421 0.1334 1.05 0.986,1.11 1119 11284
694.3 Vascular disorders of skin dermatologic Both 0.798 1.03 0.812,1.31 69 686 0.7852 1.03 0.812,1.32 67 683
695 Erythematous conditions dermatologic Both 0.009333 1.05 1.01,1.09 3180 24642 0.4467 1.04 0.944,1.14 488 5028
695.2 Bullous dermatoses dermatologic Both 0.798 0.968 0.757,1.24 68 658 0.8831 1.02 0.793,1.31 65 650
695.3 Rosacea dermatologic Both 0.009333 1.08 1.02,1.14 1405 14019 0.02512 1.07 1.01,1.13 1379 13835
695.4 Lupus (localized and systemic) dermatologic Both 0.9817 1.0 0.917,1.09 556 5556 0.7079 0.983 0.896,1.08 512 5234
695.41 Cutaneous lupus erythematosus dermatologic Both 0.7129 0.973 0.838,1.13 196 1955 0.7112 0.972 0.836,1.13 189 1934
695.42 Systemic lupus erythematosus dermatologic Both 0.7745 0.987 0.901,1.08 530 5287 0.7079 0.983 0.896,1.08 512 5234
695.7 Prurigo and Lichen dermatologic Both 0.1977 1.07 0.967,1.18 429 4275 0.1403 1.08 0.976,1.19 418 4215
695.8 Other specified erythematous conditions dermatologic Both 0.5572 1.03 0.943,1.11 613 6111 0.4989 1.03 0.946,1.12 589 6030
695.9 Unspecified erythematous condition dermatologic Both 0.4624 1.03 0.944,1.13 513 5102 0.4467 1.04 0.944,1.14 488 5028
696 Psoriasis and related disorders dermatologic Both 0.5058 1.02 0.96,1.09 1080 10781 0.006457 1.21 1.05,1.38 221 2220
696.3 Pityriasis dermatologic Both 0.3381 1.12 0.886,1.42 64 640 0.3388 1.12 0.886,1.42 64 632
696.4 Psoriasis dermatologic Both 0.6577 1.01 0.951,1.08 1014 10115 0.006457 1.21 1.05,1.38 221 2220
696.41 Psoriasis vulgaris dermatologic Both 0.857 1.01 0.94,1.08 918 9161 0.9376 1.0 0.936,1.07 898 9040
696.42 Psoriatic arthropathy dermatologic Both 0.005129 1.21 1.06,1.39 225 2250 0.006457 1.21 1.05,1.38 221 2220
697 Sarcoidosis dermatologic Both 0.6124 0.968 0.853,1.1 265 2650 0.6592 0.972 0.855,1.1 258 2617
698 Pruritus and related conditions dermatologic Both 0.4656 0.981 0.933,1.03 1686 16680 0.5623 0.985 0.936,1.04 1649 16441
700 Corns and callosities dermatologic Both 0.1014 1.06 0.988,1.14 764 7615 0.1455 1.06 0.981,1.14 735 7489
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.06918 1.03 0.998,1.06 5838 31889 0.1637 1.09 0.967,1.22 323 3210
701.1 Keratoderma, acquired dermatologic Both 0.415 1.04 0.942,1.16 389 3845 0.4764 1.04 0.936,1.15 378 3776
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.4519 1.02 0.97,1.07 1705 16953 0.5821 1.01 0.964,1.07 1677 16722
701.3 Circumscribed scleroderma dermatologic Both 0.02239 1.12 1.02,1.24 434 4334 0.01622 1.13 1.02,1.25 427 4283
701.4 Keloid scar dermatologic Both 0.9727 1.0 0.91,1.1 454 4503 0.9795 1.0 0.909,1.1 444 4448
701.5 Abnormal granulation tissue dermatologic Both 0.1459 1.09 0.971,1.22 328 3260 0.1637 1.09 0.967,1.22 323 3210
702 Degenerative skin conditions and other dermatoses dermatologic Both 5.129E-6 1.07 1.04,1.11 5351 24908 0.912 1.02 0.777,1.33 61 618
702.1 Actinic keratosis dermatologic Both 2.63E-8 1.11 1.07,1.15 3236 22206 2.239E-7 1.11 1.06,1.15 3134 21879
702.2 Seborrheic keratosis dermatologic Both 2.512E-4 1.06 1.03,1.1 4151 26248 0.001259 1.06 1.02,1.09 4026 25899
702.4 Degenerative skin disorders dermatologic Both 0.9661 1.01 0.772,1.31 63 624 0.912 1.02 0.777,1.33 61 618
703 Diseases of nail, NOS dermatologic Both 0.6745 1.01 0.951,1.08 1033 10222 0.6053 1.02 0.938,1.12 556 5685
703.1 Ingrowing nail dermatologic Both 0.6166 1.02 0.939,1.11 580 5773 0.6053 1.02 0.938,1.12 556 5685
704 Diseases of hair and hair follicles dermatologic Both 0.8318 0.995 0.954,1.04 2321 22718 0.04898 1.06 1.0,1.12 1250 12629
704.1 Alopecia dermatologic Both 0.006918 0.916 0.859,0.976 1074 10601 0.6166 0.933 0.711,1.22 54 572
704.11 Alopecia Areata dermatologic Both 0.5117 0.916 0.703,1.19 58 580 0.6166 0.933 0.711,1.22 54 572
704.2 Hirsutism dermatologic Both 0.8054 0.983 0.858,1.13 227 2263 0.6918 0.973 0.849,1.12 224 2243
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.06457 1.06 0.997,1.12 1286 12791 0.04898 1.06 1.0,1.12 1250 12629
705 Disorders of sweat glands dermatologic Both 0.8995 0.994 0.901,1.1 439 4376 0.4055 0.97 0.902,1.04 822 8324
705.1 Dyshidrosis dermatologic Both 0.1663 1.15 0.944,1.4 114 1131 0.2183 1.13 0.929,1.38 113 1115
705.3 Hidradenitis dermatologic Both 0.1455 0.892 0.765,1.04 183 1815 0.2223 0.908 0.778,1.06 179 1797
705.8 Hyperhidrosis dermatologic Both 0.4266 0.971 0.904,1.04 846 8429 0.4055 0.97 0.902,1.04 822 8324
706 Diseases of sebaceous glands dermatologic Both 0.5483 1.01 0.978,1.04 4454 32859 0.1718 1.04 0.981,1.11 1089 10944
706.1 Acne dermatologic Both 0.5848 1.01 0.967,1.06 1931 17499 0.5284 1.02 0.968,1.06 1887 17340
706.2 Sebaceous cyst dermatologic Both 0.929 1.0 0.958,1.05 2150 21106 0.7709 1.01 0.962,1.05 2095 20813
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.1472 1.05 0.984,1.11 1124 11122 0.1718 1.04 0.981,1.11 1089 10944
707 Chronic ulcer of skin dermatologic Both 0.8995 0.997 0.954,1.04 2193 21811 0.9162 0.997 0.941,1.06 1294 13172
707.1 Decubitus ulcer dermatologic Both 0.2529 0.952 0.875,1.04 600 5984 0.1963 0.944 0.866,1.03 562 5889
707.2 Chronic ulcer of leg or foot dermatologic Both 0.2495 1.05 0.969,1.13 721 7166 0.413 1.03 0.956,1.12 688 7054
707.3 Chronic ulcer of unspecified site dermatologic Both 0.9484 0.998 0.943,1.06 1339 13370 0.9162 0.997 0.941,1.06 1294 13172
709 Diffuse diseases of connective tissue dermatologic Both 0.151 1.05 0.983,1.11 1086 10825 0.4898 1.03 0.949,1.12 637 6485
709.2 Sicca syndrome dermatologic Both 0.2767 1.06 0.953,1.18 365 3650 0.2323 1.07 0.958,1.19 357 3595
709.3 Systemic sclerosis dermatologic Both 0.9183 1.01 0.865,1.17 184 1840 0.955 1.0 0.861,1.17 180 1825
709.5 Dermatomyositis dermatologic Both 0.3597 1.12 0.877,1.44 70 700 0.4634 1.1 0.856,1.41 69 692
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.1774 0.85 0.671,1.08 78 780 0.1963 0.855 0.675,1.08 77 773
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.3236 1.04 0.961,1.13 659 6563 0.4898 1.03 0.949,1.12 637 6485
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.1528 1.02 0.992,1.05 5120 27320 0.5808 0.928 0.711,1.21 62 611
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.6039 0.933 0.716,1.21 64 626 0.5808 0.928 0.711,1.21 62 611
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.5272 0.979 0.916,1.05 954 9524 0.2951 0.963 0.896,1.03 832 8540
710.1 Osteomyelitis musculoskeletal Both 0.52 0.978 0.913,1.05 914 9127 0.2951 0.963 0.896,1.03 832 8540
710.11 Acute osteomyelitis musculoskeletal Both 0.7621 1.02 0.92,1.12 425 4234 0.9727 0.998 0.903,1.1 403 4175
710.12 Chronic osteomyelitis musculoskeletal Both 0.8892 0.992 0.891,1.1 378 3758 0.5047 0.963 0.863,1.08 358 3692
710.19 Unspecified osteomyelitis musculoskeletal Both 0.456 0.974 0.908,1.04 867 8656 0.2951 0.963 0.896,1.03 832 8540
711 Arthropathy associated with infections musculoskeletal Both 0.5916 1.03 0.917,1.16 314 3124 0.4677 1.05 0.913,1.22 211 2177
711.1 Pyogenic arthritis musculoskeletal Both 0.2618 1.08 0.942,1.25 223 2206 0.4677 1.05 0.913,1.22 211 2177
712 Infective connective tissue disorders musculoskeletal Both 0.07244 0.848 0.709,1.01 136 1360 0.03631 0.821 0.683,0.988 129 1340
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.6887 1.03 0.898,1.18 222 2214 0.8414 1.02 0.845,1.23 114 1163
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.9705 1.0 0.833,1.21 118 1180 0.8414 1.02 0.845,1.23 114 1163
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.1542 1.04 0.986,1.09 1649 14662 0.1309 1.04 0.987,1.11 1302 12173
714.1 Rheumatoid arthritis musculoskeletal Both 0.05623 1.06 0.999,1.12 1342 12332 0.1309 1.04 0.987,1.11 1302 12173
715 Other inflammatory spondylopathies musculoskeletal Both 0.877 1.01 0.941,1.07 979 9761 0.7228 0.972 0.83,1.14 173 1742
715.1 Sacroiliitis NEC musculoskeletal Both 0.6353 0.967 0.84,1.11 212 2120 0.6081 0.964 0.836,1.11 208 2088
715.2 Ankylosing spondylitis musculoskeletal Both 0.6637 0.966 0.827,1.13 177 1760 0.7228 0.972 0.83,1.14 173 1742
716 Other arthropathies musculoskeletal Both 0.9354 1.0 0.978,1.02 10893 26011 1.0 1.0 0.977,1.02 10615 25704
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.3606 0.926 0.787,1.09 155 1540 0.1828 0.892 0.754,1.06 148 1521
716.2 Unspecified monoarthritis musculoskeletal Both 0.5848 0.948 0.782,1.15 116 1156 0.6745 0.959 0.791,1.16 115 1144
716.9 Arthropathy NOS musculoskeletal Both 0.867 1.0 0.979,1.03 10831 26002 1.0 1.0 0.977,1.02 10615 25704
717 Polymyalgia Rheumatica musculoskeletal Both 0.871 1.01 0.878,1.17 210 2061 0.7586 1.02 0.886,1.18 203 2024
720 Spinal stenosis musculoskeletal Both 0.4753 0.987 0.951,1.02 3298 24117 0.3443 0.98 0.938,1.02 2358 20157
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.3999 0.982 0.941,1.02 2415 20454 0.3443 0.98 0.938,1.02 2358 20157
721 Spondylosis and allied disorders musculoskeletal Both 0.7516 1.01 0.974,1.04 4494 27007 0.1936 1.1 0.953,1.27 208 2075
721.1 Spondylosis without myelopathy musculoskeletal Both 0.5012 1.01 0.979,1.05 4206 26584 0.561 1.01 0.977,1.04 4104 26251
721.2 Spondylosis with myelopathy musculoskeletal Both 0.7047 0.985 0.913,1.06 740 7398 0.6637 0.983 0.911,1.06 727 7294
721.8 Other allied disorders of spine musculoskeletal Both 0.3141 1.07 0.934,1.24 212 2099 0.1936 1.1 0.953,1.27 208 2075
722 Intervertebral disc disorders musculoskeletal Both 0.2818 1.02 0.987,1.05 5242 28702 0.7727 1.01 0.956,1.06 1544 15463
722.1 Displacement of intervertebral disc musculoskeletal Both 0.8185 1.0 0.967,1.04 3038 26827 0.7031 1.01 0.97,1.05 2967 26500
722.3 Schmorl's nodes musculoskeletal Both 0.8241 1.02 0.843,1.24 115 1140 0.6471 1.05 0.859,1.28 107 1129
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.07079 1.03 0.997,1.07 3338 26140 0.0912 1.03 0.995,1.07 3248 25810
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.5508 1.03 0.936,1.13 464 4634 0.4842 1.03 0.94,1.14 458 4562
722.8 Postlaminectomy syndrome musculoskeletal Both 0.6823 0.977 0.872,1.09 336 3360 0.6761 0.976 0.871,1.09 333 3308
722.9 Other and unspecified disc disorder musculoskeletal Both 0.8072 1.01 0.955,1.06 1569 15676 0.7727 1.01 0.956,1.06 1544 15463
723 Other disorders of cervical region musculoskeletal Both 0.7047 1.01 0.942,1.09 761 7610 0.2864 1.08 0.935,1.25 185 1847
723.1 Torticollis musculoskeletal Both 0.2239 1.09 0.946,1.27 187 1870 0.2864 1.08 0.935,1.25 185 1847
724 Other and unspecified disorders of back musculoskeletal Both 0.6546 0.992 0.957,1.03 3338 26730 0.6266 1.01 0.957,1.08 1211 12252
724.1 Disorders of sacrum musculoskeletal Both 0.6324 0.988 0.941,1.04 1804 17663 0.7178 0.991 0.943,1.04 1763 17457
724.2 Disorders of coccyx musculoskeletal Both 0.6095 1.03 0.92,1.15 331 3290 0.5957 1.03 0.92,1.16 320 3250
724.8 Other symptoms referable to back musculoskeletal Both 0.4457 0.971 0.902,1.05 753 7499 0.5309 0.976 0.905,1.05 736 7422
724.9 Other unspecified back disorders musculoskeletal Both 0.7178 1.01 0.954,1.07 1246 12418 0.6266 1.01 0.957,1.08 1211 12252
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.7568 1.0 0.979,1.03 7682 25455 0.5861 1.02 0.952,1.09 877 8742
726.1 Enthesopathy musculoskeletal Both 0.7691 1.0 0.976,1.03 5795 25454 0.8337 1.0 0.974,1.03 5696 25179
726.2 Synoviopathy musculoskeletal Both 0.6081 1.02 0.947,1.1 774 7723 0.6561 1.02 0.944,1.1 759 7632
726.3 Bursitis musculoskeletal Both 0.9141 1.0 0.948,1.06 1339 13090 0.8414 1.01 0.95,1.06 1313 12940
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.4529 1.03 0.959,1.1 889 8846 0.5861 1.02 0.952,1.09 877 8742
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.9683 0.999 0.971,1.03 5811 25457 0.5212 0.938 0.772,1.14 115 1110
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.4498 1.02 0.974,1.06 2342 20541 0.4416 1.02 0.974,1.06 2300 20318
727.2 Bursitis disorders musculoskeletal Both 0.9683 0.998 0.89,1.12 341 3381 0.8375 0.988 0.88,1.11 330 3340
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.0955 0.948 0.891,1.01 1109 11034 0.1016 0.949 0.891,1.01 1085 10923
727.5 Rupture of synovium musculoskeletal Both 0.9333 1.0 0.904,1.12 376 3718 0.8128 1.01 0.91,1.13 367 3670
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.3917 0.979 0.934,1.03 1927 18092 0.3048 0.975 0.93,1.02 1897 17854
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.2704 0.951 0.869,1.04 520 5187 0.2148 0.944 0.863,1.03 511 5135
727.8 Plica syndrome musculoskeletal Both 0.5152 0.937 0.771,1.14 115 1117 0.5212 0.938 0.772,1.14 115 1110
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.3311 0.982 0.947,1.02 3433 24951 0.1054 1.1 0.98,1.24 300 3049
728.1 Muscular calcification and ossification musculoskeletal Both 0.7328 1.04 0.817,1.33 69 682 0.9705 0.995 0.773,1.28 66 677
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.6281 1.03 0.902,1.19 230 2298 0.7328 1.02 0.892,1.18 226 2267
728.7 Fasciitis musculoskeletal Both 0.6776 0.99 0.946,1.04 2056 19042 0.1054 1.1 0.98,1.24 300 3049
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.06918 1.11 0.992,1.25 310 3095 0.1054 1.1 0.98,1.24 300 3049
729 Other disorders of soft tissues musculoskeletal Both 0.07244 1.04 0.997,1.08 2618 22751 0.6637 1.05 0.855,1.28 99 993
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.1618 1.21 0.927,1.57 63 630 0.16 1.21 0.928,1.58 62 623
729.3 Panniculitis musculoskeletal Both 0.7178 1.04 0.849,1.27 100 1000 0.6637 1.05 0.855,1.28 99 993
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.3767 0.876 0.654,1.17 53 530 ,
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.7907 1.02 0.863,1.21 145 1441 0.6053 1.05 0.88,1.25 137 1418
732 Osteochondropathies musculoskeletal Both 0.8395 0.988 0.876,1.11 289 2882 0.6622 0.948 0.747,1.2 70 707
732.1 Juvenile osteochondrosis musculoskeletal Both 0.8453 0.984 0.834,1.16 157 1570 0.7568 0.974 0.824,1.15 152 1555
732.7 Osteochondritis dissecans musculoskeletal Both 0.6699 0.95 0.749,1.2 71 710 0.6622 0.948 0.747,1.2 70 707
733 Other disorders of bone and cartilage musculoskeletal Both 0.4426 0.986 0.95,1.02 3481 21966 0.537 0.928 0.732,1.18 79 797
733.2 Cyst of bone musculoskeletal Both 0.2698 0.912 0.773,1.07 162 1613 0.3243 0.92 0.78,1.09 160 1584
733.4 Aseptic necrosis of bone musculoskeletal Both 0.1778 1.07 0.969,1.19 405 4042 0.2178 1.07 0.962,1.19 379 3998
733.6 Costochondritis musculoskeletal Both 0.861 1.01 0.895,1.14 275 2742 0.8185 1.01 0.897,1.15 267 2722
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.0871 0.933 0.863,1.01 701 7003 0.1167 0.938 0.867,1.02 687 6930
733.9 Chondromalacia musculoskeletal Both 0.4688 0.916 0.724,1.16 80 800 0.537 0.928 0.732,1.18 79 797
735 Acquired foot deformities musculoskeletal Both 0.2472 0.975 0.935,1.02 2431 23304 0.4227 1.03 0.963,1.09 1022 10145
735.1 Flat foot musculoskeletal Both 0.03236 0.899 0.815,0.991 437 4355 0.02399 0.892 0.808,0.985 429 4286
735.2 Acquired toe deformities musculoskeletal Both 0.9661 0.998 0.931,1.07 869 8616 0.8995 0.992 0.881,1.12 296 2941
735.21 Hammer toe (acquired) musculoskeletal Both 0.3954 1.04 0.95,1.14 509 5041 0.4227 1.04 0.947,1.14 490 4959
735.23 Hallux rigidus musculoskeletal Both 0.9683 0.998 0.886,1.12 299 2975 0.8995 0.992 0.881,1.12 296 2941
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.4036 1.03 0.964,1.1 1039 10308 0.4227 1.03 0.963,1.09 1022 10145
736 Other acquired deformities of limbs musculoskeletal Both 0.695 0.991 0.946,1.04 1997 19771 0.9886 1.0 0.878,1.14 250 2522
736.1 Acquired deformities of forearm musculoskeletal Both 0.1064 1.19 0.964,1.46 90 892 0.1496 1.17 0.944,1.46 86 877
736.2 Acquired deformities of finger musculoskeletal Both 0.4406 1.06 0.912,1.24 169 1684 0.4989 1.05 0.904,1.23 166 1662
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.1178 0.898 0.785,1.03 239 2382 0.1337 0.902 0.788,1.03 238 2340
736.5 Acquired deformities of knee musculoskeletal Both 0.1265 0.885 0.757,1.03 184 1834 0.1549 0.892 0.762,1.04 182 1809
736.6 Unequal leg length (acquired) musculoskeletal Both 0.9977 1.0 0.879,1.14 256 2555 0.9886 1.0 0.878,1.14 250 2522
737 Curvature of spine musculoskeletal Both 0.8241 0.993 0.937,1.05 1268 12573 0.8035 0.992 0.927,1.06 962 9641
737.1 Kyphosis (acquired) musculoskeletal Both 0.743 0.982 0.884,1.09 383 3819 0.9141 0.994 0.893,1.11 372 3752
737.2 Lordosis (acquired) musculoskeletal Both 0.5888 0.93 0.713,1.21 65 650 0.5662 0.925 0.709,1.21 65 638
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.826 0.993 0.929,1.06 987 9782 0.8035 0.992 0.927,1.06 962 9641
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.6577 0.99 0.945,1.04 1968 19555 0.7311 0.988 0.921,1.06 853 8455
738.4 Acquired spondylolisthesis musculoskeletal Both 0.7907 0.991 0.924,1.06 863 8617 0.7311 0.988 0.921,1.06 853 8455
739 Contracture of joint musculoskeletal Both 0.871 1.01 0.922,1.1 522 5203 0.8222 0.99 0.905,1.08 503 5145
740 Osteoarthrosis musculoskeletal Both 0.9397 1.0 0.979,1.02 13133 25195 0.8831 1.0 0.979,1.02 12401 24790
740.1 Osteoarthritis; localized musculoskeletal Both 0.6209 0.992 0.962,1.02 5329 22764 0.6577 0.98 0.894,1.07 509 5059
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.6823 1.01 0.974,1.04 4543 21500 0.7447 1.01 0.973,1.04 4464 21240
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.673 0.981 0.895,1.07 514 5125 0.6577 0.98 0.894,1.07 509 5059
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.6053 1.02 0.957,1.08 1266 9917 0.7328 1.01 0.952,1.07 1235 9765
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.375 0.948 0.841,1.07 303 2974 0.3524 0.944 0.836,1.07 291 2927
740.9 Osteoarthrosis NOS musculoskeletal Both 0.811 1.0 0.98,1.03 12648 25075 0.8831 1.0 0.979,1.02 12401 24790
741 Symptoms and disorders of the joints musculoskeletal Both 0.4742 1.01 0.983,1.04 6764 29838 0.4426 1.12 0.841,1.49 53 514
741.1 Ankylosis of joint musculoskeletal Both 0.3908 0.939 0.814,1.08 209 2088 0.3475 0.933 0.808,1.08 206 2061
741.2 Stiffness of joint musculoskeletal Both 0.6281 0.984 0.922,1.05 995 9908 0.7362 0.989 0.926,1.06 971 9782
741.3 Difficulty in walking musculoskeletal Both 0.8933 0.997 0.95,1.05 1854 17778 0.8872 0.996 0.949,1.05 1779 17538
741.4 Joint effusions musculoskeletal Both 0.8995 1.0 0.957,1.05 1930 19185 0.929 1.0 0.956,1.05 1881 18960
741.5 Hemarthrosis musculoskeletal Both 0.01479 1.34 1.06,1.7 64 640 0.02884 1.31 1.03,1.66 62 633
741.6 Villonodular synovitis musculoskeletal Both 0.4217 1.12 0.846,1.49 53 522 0.4426 1.12 0.841,1.49 53 514
742 Derangement of joint, non-traumatic musculoskeletal Both 0.1483 1.03 0.991,1.06 3462 27650 0.2812 1.02 0.983,1.06 3146 26591
742.1 Loose body in joint musculoskeletal Both 0.8299 0.981 0.82,1.17 131 1295 0.7031 0.966 0.806,1.16 129 1284
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.9226 0.994 0.872,1.13 243 2414 0.984 1.0 0.878,1.14 239 2390
742.8 Articular cartilage disorder musculoskeletal Both 0.5781 1.04 0.9,1.21 191 1896 0.5794 1.04 0.9,1.21 191 1884
742.9 Other derangement of joint musculoskeletal Both 0.2748 1.02 0.984,1.06 3212 26883 0.2812 1.02 0.983,1.06 3146 26591
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.2612 1.02 0.989,1.04 7571 30458 0.7691 1.0 0.975,1.03 5620 29141
743.1 Osteoporosis musculoskeletal Both 0.3373 1.02 0.979,1.06 2982 15823 0.4887 0.951 0.826,1.1 217 2261
743.11 Osteoporosis NOS musculoskeletal Both 0.3837 1.02 0.977,1.06 2931 15630 0.3258 1.02 0.979,1.06 2852 15447
743.12 Senile osteoporosis musculoskeletal Both 0.9354 0.996 0.905,1.1 481 4333 0.8492 0.991 0.899,1.09 469 4283
743.13 Other specified osteoporosis musculoskeletal Both 0.5212 0.956 0.834,1.1 231 2290 0.4887 0.951 0.826,1.1 217 2261
743.2 Pathologic fracture musculoskeletal Both 0.133 1.05 0.984,1.13 872 8504 0.5821 1.06 0.868,1.29 110 1133
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.507 1.04 0.934,1.15 385 3799 0.3319 1.06 0.947,1.18 345 3756
743.22 Pathologic fracture of femur musculoskeletal Both 0.7762 1.03 0.849,1.24 116 1143 0.5821 1.06 0.868,1.29 110 1133
743.4 Stress fracture musculoskeletal Both 0.4446 1.05 0.929,1.18 291 2882 0.3936 1.06 0.932,1.19 277 2865
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.7295 1.01 0.976,1.03 5795 29464 0.7691 1.0 0.975,1.03 5620 29141
745 Pain in joint musculoskeletal Both 0.6368 0.995 0.975,1.02 15755 22596 0.5346 0.993 0.973,1.01 15454 22352
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.4365 0.981 0.935,1.03 1811 18049 0.3214 0.949 0.855,1.05 395 3970
747.1 Cardiac congenital anomalies congenital anomalies Both 0.6209 0.986 0.934,1.04 1446 14417 0.7516 1.02 0.91,1.14 332 3334
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.6516 1.02 0.933,1.12 519 5181 0.7311 1.02 0.928,1.11 505 5121
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.7834 0.988 0.91,1.07 632 6299 0.8395 0.991 0.912,1.08 613 6189
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.695 1.02 0.915,1.14 342 3387 0.7516 1.02 0.91,1.14 332 3334
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.3819 0.955 0.862,1.06 402 4014 0.3214 0.949 0.855,1.05 395 3970
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.881 0.984 0.795,1.22 93 930 0.9036 0.987 0.796,1.22 91 913
749 Congenital anomalies of face and neck congenital anomalies Both 0.4508 0.964 0.876,1.06 455 4540 0.0912 0.832 0.672,1.03 90 889
749.1 Cleft palate congenital anomalies Both 0.542 1.07 0.861,1.33 81 791 0.5483 1.07 0.86,1.33 81 785
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.0912 0.832 0.672,1.03 90 897 0.0912 0.832 0.672,1.03 90 889
750 Digestive congenital anomalies congenital anomalies Both 0.4395 0.97 0.899,1.05 739 7382 0.7031 0.971 0.833,1.13 175 1772
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.6699 0.975 0.868,1.1 307 3069 0.04571 0.753 0.571,0.994 55 560
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.5585 1.06 0.867,1.3 96 944 0.5675 1.06 0.864,1.3 94 932
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.9354 1.01 0.809,1.26 77 767 0.8433 1.02 0.818,1.28 75 754
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.5546 0.944 0.779,1.14 121 1210 0.5309 0.94 0.775,1.14 120 1182
750.15 Congenital anomalies of stomach congenital anomalies Both 0.03981 0.75 0.57,0.986 57 567 0.04571 0.753 0.571,0.994 55 560
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.7228 0.982 0.89,1.08 438 4363 0.7031 0.971 0.833,1.13 175 1772
750.21 Congenital anomalies of intestine congenital anomalies Both 0.8872 0.991 0.872,1.13 262 2613 0.8531 0.988 0.869,1.12 257 2582
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.7709 0.978 0.841,1.14 180 1790 0.7031 0.971 0.833,1.13 175 1772
751 Genitourinary congenital anomalies congenital anomalies Both 0.9268 0.998 0.949,1.05 1682 16764 0.114 1.14 0.97,1.33 154 1545
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.5875 0.975 0.889,1.07 491 4897 0.5248 0.943 0.788,1.13 129 1275
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.5433 0.966 0.863,1.08 328 3280 0.526 0.964 0.862,1.08 324 3249
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.5333 0.945 0.792,1.13 132 1301 0.5248 0.943 0.788,1.13 129 1275
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.9638 1.0 0.942,1.06 1139 11355 0.8472 1.01 0.891,1.15 247 2473
751.21 Cystic kidney disease congenital anomalies Both 0.6223 1.02 0.947,1.09 799 7929 0.6918 1.01 0.943,1.09 773 7800
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.861 1.01 0.89,1.15 251 2506 0.8472 1.01 0.891,1.15 247 2473
751.3 Obstructive genitourinary defect congenital anomalies Both 0.1849 1.11 0.95,1.3 157 1560 0.114 1.14 0.97,1.33 154 1545
752 Nervous system congenital anomalies congenital anomalies Both 0.4831 0.976 0.912,1.04 908 9073 0.1923 0.906 0.781,1.05 196 1979
752.1 Neural tube defects congenital anomalies Both 0.7244 0.986 0.914,1.06 728 7277 0.7586 1.03 0.865,1.22 144 1425
752.11 Spina bifida congenital anomalies Both 0.7413 1.03 0.866,1.22 144 1440 0.7586 1.03 0.865,1.22 144 1425
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.3597 0.934 0.808,1.08 201 2010 0.1923 0.906 0.781,1.05 196 1979
753 Congenital anomalies of the eye congenital anomalies Both 0.2153 0.899 0.759,1.06 146 1451 0.1742 0.888 0.749,1.05 143 1430
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.2113 0.959 0.898,1.02 1006 10049 0.1479 0.931 0.846,1.03 464 4582
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.5408 0.942 0.778,1.14 116 1155 0.5875 0.948 0.783,1.15 115 1144
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.2123 0.941 0.855,1.04 470 4675 0.1479 0.931 0.846,1.03 464 4582
755 Congenital anomalies of limbs congenital anomalies Both 0.5875 0.978 0.901,1.06 625 6237 0.9441 1.01 0.853,1.19 151 1506
755.1 Congenital deformities of feet congenital anomalies Both 0.5754 0.968 0.864,1.08 315 3138 0.5821 0.968 0.864,1.09 311 3092
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.05248 1.29 0.997,1.67 58 567 0.03311 1.33 1.02,1.72 57 560
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.5188 0.959 0.844,1.09 258 2580 0.9441 1.01 0.853,1.19 151 1506
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.9817 1.0 0.85,1.18 152 1520 0.9441 1.01 0.853,1.19 151 1506
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.0195 0.925 0.867,0.988 1021 10203 0.05248 0.926 0.856,1.0 714 7324
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.865 1.02 0.778,1.35 55 527 0.9661 0.994 0.751,1.32 53 520
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.2163 0.845 0.648,1.1 56 524 0.2089 0.842 0.644,1.1 56 520
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.0631 0.881 0.771,1.01 246 2459 0.07943 0.887 0.776,1.01 245 2432
756.5 Congenital osteodystrophies congenital anomalies Both 0.06607 0.931 0.862,1.0 743 7419 0.05248 0.926 0.856,1.0 714 7324
757 Congenital anomalies of the integument congenital anomalies Both 0.1365 1.1 0.971,1.24 283 2820 0.2472 1.08 0.951,1.22 273 2786
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.5623 1.05 0.881,1.26 134 1334 0.3436 1.11 0.892,1.39 86 904
758.1 Chromosomal anomalies congenital anomalies Both 0.5152 1.07 0.866,1.33 91 910 0.3436 1.11 0.892,1.39 86 904
759 Other and unspecified congenital anomalies congenital anomalies Both 0.2113 0.943 0.86,1.03 498 4964 0.4732 0.902 0.679,1.2 57 556
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.4667 0.9 0.678,1.2 57 567 0.4732 0.902 0.679,1.2 57 556
760 Back pain symptoms Both 0.4592 1.01 0.987,1.03 12687 25663 0.547 1.01 0.985,1.03 12431 25374
761 Cervicalgia symptoms Both 0.8166 1.0 0.974,1.03 5134 32829 0.9886 1.0 0.971,1.03 5036 32384
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.9484 1.0 0.964,1.04 2927 27356 0.9594 0.999 0.961,1.04 2864 26973
764 Sciatica symptoms Both 0.26 0.977 0.938,1.02 2623 25291 0.207 0.974 0.935,1.01 2557 24942
765 Cervical radiculitis symptoms Both 0.6699 0.988 0.935,1.04 1401 13966 0.6353 0.987 0.934,1.04 1382 13777
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.6561 1.01 0.975,1.04 4004 31031 0.6516 1.01 0.975,1.04 3921 30629
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.5728 0.936 0.745,1.18 85 835 0.6166 0.943 0.75,1.19 84 825
769 Nonallopathic lesions NEC symptoms Both 0.9954 1.0 0.934,1.07 923 9183 0.877 0.995 0.928,1.07 902 9051
770 Myalgia and myositis unspecified symptoms Both 0.4198 0.987 0.955,1.02 4324 27592 0.4036 0.986 0.954,1.02 4236 27224
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.4529 1.01 0.979,1.05 3638 29710 0.8414 0.992 0.92,1.07 747 7769
771.1 Swelling of limb symptoms Both 0.3396 1.02 0.984,1.05 4511 29862 0.5585 1.01 0.978,1.04 4340 29556
771.2 Cramp of limb symptoms Both 0.547 0.978 0.908,1.05 791 7856 0.8414 0.992 0.92,1.07 747 7769
772 Symptoms of the muscles symptoms Both 0.8472 1.01 0.954,1.06 1549 15345 0.07079 1.1 0.991,1.23 367 3701
772.1 Muscular wasting and disuse atrophy symptoms Both 0.8279 0.988 0.883,1.11 320 3187 0.8072 0.986 0.88,1.1 312 3145
772.2 Spasm of muscle symptoms Both 0.5164 0.984 0.937,1.03 1780 17782 0.6053 0.987 0.939,1.04 1736 17601
772.3 Muscle weakness symptoms Both 0.3062 0.978 0.937,1.02 2339 22770 0.2393 0.974 0.932,1.02 2247 22449
772.4 Rhabdomyolysis symptoms Both 0.9908 0.999 0.828,1.2 117 1170 0.9908 1.0 0.825,1.22 108 1157
772.6 Facial weakness symptoms Both 0.0871 1.1 0.987,1.22 377 3746 0.07079 1.1 0.991,1.23 367 3701
773 Pain in limb symptoms Both 0.5768 0.994 0.972,1.02 11393 26958 0.414 0.991 0.969,1.01 11154 26652
780 Hypothermia/Chills symptoms Both 0.6039 0.969 0.862,1.09 307 3069 0.4581 0.955 0.847,1.08 289 3016
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.6998 0.99 0.943,1.04 1767 17206 0.01445 1.3 1.05,1.62 87 869
781.1 Loss of height symptoms Both 0.02089 1.28 1.04,1.58 91 890 0.01445 1.3 1.05,1.62 87 869
782.3 Edema symptoms Both 0.826 1.0 0.973,1.04 4591 30849 0.869 1.0 0.971,1.04 4411 30506
782.6 Pallor and flushing symptoms Both 0.9311 1.0 0.928,1.09 679 6769 0.8279 0.991 0.915,1.07 662 6703
783 Fever of unknown origin symptoms Both 0.3258 1.02 0.985,1.05 4616 33703 0.7015 1.03 0.898,1.17 243 2442
783.1 Postprocedural fever symptoms Both 0.5715 1.04 0.91,1.19 248 2473 0.7015 1.03 0.898,1.17 243 2442
785 Abdominal pain symptoms Both 0.5445 0.993 0.972,1.01 13257 25098 0.3758 0.99 0.969,1.01 12977 24833
788 Syncope and collapse symptoms Both 0.007586 1.05 1.01,1.09 3017 29114 0.00955 1.05 1.01,1.09 2927 28708
789 Nausea and vomiting symptoms Both 0.00389 1.04 1.01,1.06 8497 29838 0.4721 1.03 0.949,1.12 617 6275
789.1 Persistent vomiting symptoms Both 0.4295 1.03 0.953,1.12 634 6330 0.4721 1.03 0.949,1.12 617 6275
790 Nonspecific findings on examination of blood symptoms Both 0.8166 0.994 0.946,1.04 1740 17356 0.07079 1.19 0.985,1.43 118 1217
790.1 Elevated sedimentation rate symptoms Both 0.857 0.985 0.838,1.16 158 1580 0.912 0.991 0.839,1.17 150 1568
790.6 Other abnormal blood chemistry symptoms Both 0.857 1.0 0.973,1.03 4849 31554 0.9419 1.0 0.971,1.03 4675 31255
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.3069 1.08 0.934,1.24 204 2026 0.2056 1.1 0.95,1.27 200 2010
790.9 Abnormal arterial blood gases symptoms Both 0.0309 1.22 1.02,1.46 123 1230 0.07079 1.19 0.985,1.43 118 1217
791 Gangrene symptoms Both 0.1422 1.11 0.966,1.27 212 2104 0.1416 1.11 0.965,1.28 203 2069
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.9036 1.0 0.957,1.05 2171 11972 0.02399 1.09 1.01,1.17 828 7755
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.0263 1.08 1.01,1.16 841 7806 0.02399 1.09 1.01,1.17 828 7755
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.4102 1.04 0.952,1.13 588 5848 0.6982 0.99 0.94,1.04 1592 16356
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.7551 0.992 0.943,1.04 1661 16601 0.6982 0.99 0.94,1.04 1592 16356
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.7534 1.02 0.922,1.12 433 4330 0.875 1.01 0.913,1.11 423 4269
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.1687 0.965 0.916,1.02 1632 15619 0.06457 0.858 0.729,1.01 164 1641
795.8 Abnormal tumor markers symptoms Both 0.01778 0.94 0.894,0.989 1698 13664 0.06457 0.858 0.729,1.01 164 1641
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.07762 0.865 0.736,1.02 167 1662 0.06457 0.858 0.729,1.01 164 1641
796 Elevated prostate specific antigen [PSA] symptoms Male 0.1652 0.963 0.913,1.02 1700 8294 0.1791 0.964 0.913,1.02 1657 8161
797 Shock symptoms Both 0.399 1.04 0.947,1.15 445 4446 0.0631 1.15 0.992,1.34 175 1787
797.1 Cardiogenic shock symptoms Both 0.1265 1.12 0.968,1.3 183 1822 0.0631 1.15 0.992,1.34 175 1787
798 Malaise and fatigue symptoms Both 0.5408 1.01 0.984,1.03 8867 29476 0.7534 0.991 0.935,1.05 1297 13252
798.1 Chronic fatigue syndrome symptoms Both 0.6683 0.988 0.933,1.05 1349 13380 0.7534 0.991 0.935,1.05 1297 13252
799 Debility unspecified symptoms Both 0.207 1.03 0.982,1.09 1672 16007 0.1941 1.03 0.983,1.09 1574 15750
800 Fracture of lower limb injuries & poisonings Both 0.7063 1.01 0.962,1.06 1879 18684 0.7413 0.98 0.868,1.11 288 2865
800.1 Fracture of neck of femur injuries & poisonings Both 0.3289 1.05 0.951,1.16 409 4028 0.3076 1.06 0.952,1.17 392 3975
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.8551 0.992 0.908,1.08 539 5364 0.787 0.988 0.902,1.08 520 5301
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.5224 1.03 0.95,1.11 744 7420 0.4742 1.03 0.952,1.11 728 7356
800.4 Fracture of patella injuries & poisonings Both 0.7551 0.981 0.87,1.11 293 2904 0.7413 0.98 0.868,1.11 288 2865
801 Fracture of ankle and foot injuries & poisonings Both 0.1413 1.04 0.988,1.09 1804 17960 0.7112 1.01 0.946,1.08 897 8999
801.1 Fracture of foot injuries & poisonings Both 0.6486 1.02 0.95,1.09 913 9098 0.7112 1.01 0.946,1.08 897 8999
802 Fracture of pelvis injuries & poisonings Both 0.1327 1.09 0.974,1.22 321 3192 0.1795 1.08 0.964,1.22 308 3151
803 Fracture of upper limb injuries & poisonings Both 0.597 1.01 0.964,1.07 1644 16288 0.7295 1.02 0.921,1.12 412 4148
803.1 Fracture of humerus injuries & poisonings Both 0.4227 1.04 0.951,1.13 592 5913 0.3811 1.04 0.954,1.13 575 5844
803.2 Fracture of radius and ulna injuries & poisonings Both 0.4198 1.03 0.961,1.1 899 8929 0.861 0.989 0.869,1.12 244 2441
803.21 Colles' fracture injuries & poisonings Both 0.8035 0.984 0.865,1.12 248 2475 0.861 0.989 0.869,1.12 244 2441
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.5861 1.03 0.931,1.13 419 4190 0.7295 1.02 0.921,1.12 412 4148
804 Fracture of hand or wrist injuries & poisonings Both 0.6561 0.987 0.931,1.05 1272 12504 0.5534 0.982 0.927,1.04 1253 12378
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.9705 0.999 0.938,1.06 1082 10755 0.9078 0.996 0.934,1.06 1026 10613
807 Fracture of ribs injuries & poisonings Both 0.2911 1.05 0.961,1.14 543 5428 0.4581 1.03 0.946,1.13 516 5364
809 Fracture of unspecified bones injuries & poisonings Both 0.1611 1.03 0.988,1.07 2426 23282 0.138 1.03 0.99,1.08 2349 23021
817 Concussion injuries & poisonings Both 0.5105 1.03 0.952,1.1 771 7696 0.7244 1.01 0.94,1.09 751 7620
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.869 0.989 0.867,1.13 240 2380 0.5248 0.929 0.739,1.17 81 822
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.8492 1.02 0.805,1.3 74 740 0.8933 0.983 0.769,1.26 71 732
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.4688 0.92 0.735,1.15 84 837 0.5248 0.929 0.739,1.17 81 822
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.6902 0.99 0.943,1.04 1782 17605 0.5297 0.984 0.937,1.03 1743 17405
830 Dislocation injuries & poisonings Both 0.3055 1.02 0.982,1.06 3129 28682 0.3899 1.02 0.979,1.06 3078 28302
835 Internal derangement of knee injuries & poisonings Both 0.8954 1.0 0.955,1.05 1774 17453 0.875 1.0 0.956,1.05 1745 17241
836 Traumatic arthropathy injuries & poisonings Both 0.4656 1.04 0.94,1.15 423 4213 0.6442 1.02 0.927,1.13 417 4142
840 Sprains and strains injuries & poisonings Both 0.6368 0.993 0.966,1.02 6106 31582 0.2924 0.976 0.934,1.02 2242 19304
840.1 Muscle/tendon sprain injuries & poisonings Both 0.5248 0.968 0.877,1.07 429 4269 0.4285 0.96 0.869,1.06 423 4184
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.877 1.0 0.949,1.06 1343 13394 0.9795 0.999 0.944,1.06 1324 13172
840.3 Joint/ligament sprain injuries & poisonings Both 0.2679 0.975 0.933,1.02 2261 19530 0.2924 0.976 0.934,1.02 2242 19304
841 Sprains and strains of back and neck injuries & poisonings Both 0.9099 0.997 0.938,1.06 1175 11729 0.8091 0.993 0.934,1.05 1156 11596
842 Other sprains and strains injuries & poisonings Both 0.5598 1.02 0.957,1.09 1079 10729 0.5821 1.02 0.955,1.08 1061 10595
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.6918 1.01 0.962,1.06 1807 18037 0.8318 1.01 0.957,1.06 1760 17777
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.3199 1.04 0.965,1.12 797 7958 0.3304 1.04 0.963,1.12 747 7848
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.03715 1.11 1.01,1.23 398 3977 0.08128 1.1 0.989,1.21 391 3919
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.05623 1.05 0.999,1.11 1537 15333 0.0631 1.05 0.997,1.11 1467 15106
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.3162 1.07 0.94,1.21 254 2540 0.4345 1.05 0.926,1.2 247 2505
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.9247 1.01 0.889,1.14 262 2617 0.8185 1.01 0.896,1.15 256 2574
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.02291 0.933 0.878,0.99 1196 11925 0.01549 0.928 0.874,0.986 1176 11779
858 Complication of internal orthopedic device injuries & poisonings Both 0.8872 0.997 0.95,1.05 1892 18846 0.7852 0.993 0.947,1.04 1866 18616
859 Complication due to other implant and internal device injuries & poisonings Both 0.5058 0.984 0.937,1.03 1820 18191 0.3945 0.979 0.932,1.03 1776 17974
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.9397 0.999 0.964,1.03 3389 30552 0.7413 1.03 0.851,1.25 114 1154
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.7621 1.02 0.874,1.2 156 1551 0.6699 1.04 0.882,1.22 151 1526
870.2 Open wound of ear injuries & poisonings Both 0.1023 1.17 0.969,1.42 114 1131 0.1959 1.14 0.935,1.39 108 1119
870.3 Other open wound of head and face injuries & poisonings Both 0.0912 1.06 0.991,1.13 1064 10560 0.105 1.05 0.989,1.12 1032 10418
870.4 Open wound of nose and sinus injuries & poisonings Both 0.7727 0.977 0.833,1.15 168 1667 0.8453 0.984 0.837,1.16 164 1648
870.5 Open wound of lip and mouth injuries & poisonings Both 0.6457 0.969 0.846,1.11 230 2293 0.5395 0.958 0.835,1.1 225 2257
870.6 Open wound of neck injuries & poisonings Both 0.0912 0.876 0.751,1.02 184 1833 0.07244 0.867 0.742,1.01 180 1808
870.8 Open wound of genital organs injuries & poisonings Both 0.7962 1.03 0.846,1.24 117 1170 0.7413 1.03 0.851,1.25 114 1154
871 Open wounds of extremities injuries & poisonings Both 0.006457 1.06 1.02,1.1 2705 26585 0.03981 1.17 1.01,1.35 184 1871
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.857 0.991 0.899,1.09 438 4378 0.8337 0.99 0.896,1.09 429 4305
871.2 Open wound of finger(s) injuries & poisonings Both 0.9057 0.995 0.922,1.07 731 7291 0.7178 0.986 0.912,1.07 717 7187
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.00389 1.18 1.05,1.31 331 3277 0.007079 1.17 1.04,1.31 319 3240
871.4 Open wound of toe(s) injuries & poisonings Both 0.02042 1.19 1.03,1.37 191 1901 0.03981 1.17 1.01,1.35 184 1871
872 Traumatic amputation injuries & poisonings Both 0.2051 1.07 0.965,1.18 415 4129 0.2992 1.06 0.953,1.17 398 4077
873 Broken tooth injuries & poisonings Both 0.4634 0.94 0.797,1.11 148 1471 0.5058 0.945 0.801,1.12 146 1455
874 Complication of amputation stump injuries & poisonings Both 0.4613 1.07 0.893,1.28 122 1220 0.3614 1.09 0.906,1.31 117 1200
875 Non-healing surgical wound injuries & poisonings Both 0.5916 1.03 0.935,1.12 495 4950 0.673 1.02 0.929,1.12 485 4886
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.009772 1.11 1.03,1.2 669 6680 0.02291 1.1 1.01,1.19 651 6602
907 Injuries to the nervous system injuries & poisonings Both 0.2825 1.04 0.97,1.11 888 8852 0.2495 1.04 0.972,1.12 875 8706
910 Superficial injury, infected injuries & poisonings Both 0.7816 1.03 0.828,1.29 89 887 0.7211 1.04 0.833,1.3 86 875
911 Blister injuries & poisonings Both 0.929 1.01 0.865,1.17 185 1838 0.8241 1.02 0.872,1.19 178 1811
912 Insect bite injuries & poisonings Both 0.5117 1.04 0.927,1.16 321 3207 0.3673 1.05 0.94,1.18 315 3167
913 Toxic effect of venom injuries & poisonings Both 0.09772 1.11 0.98,1.27 247 2461 0.1014 1.11 0.979,1.27 243 2423
915 Superficial injury without mention of infection injuries & poisonings Both 0.8356 1.0 0.963,1.05 2368 23457 0.7907 1.01 0.964,1.05 2303 23138
916 Contusion injuries & poisonings Both 0.8337 0.996 0.96,1.03 3199 30228 0.7129 0.993 0.957,1.03 3114 29827
930 Allergic reaction to food injuries & poisonings Both 0.1854 1.06 0.973,1.15 597 5953 0.2541 1.05 0.965,1.14 583 5908
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.7816 0.988 0.903,1.08 530 5290 0.7816 0.987 0.903,1.08 528 5230
938 Dermatitis due to solar radiation injuries & poisonings Both 0.002042 1.05 1.02,1.09 4197 24407 0.01 1.05 1.01,1.08 3883 23736
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.6714 1.03 0.883,1.21 164 1640 0.869 1.01 0.863,1.19 160 1621
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.003162 1.05 1.02,1.09 4001 24007 0.01 1.05 1.01,1.08 3883 23736
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.8954 0.989 0.834,1.17 140 1400 0.7278 0.97 0.815,1.15 134 1381
942 Infusion and transfusion reaction injuries & poisonings Both 0.9204 1.01 0.875,1.16 221 2205 0.787 1.02 0.878,1.19 188 2182
946 Anaphylactic shock NOS injuries & poisonings Both 0.06918 1.1 0.992,1.22 385 3830 0.07943 1.1 0.989,1.22 374 3795
947 Urticaria injuries & poisonings Both 0.6368 1.02 0.949,1.09 889 8845 0.6427 1.02 0.948,1.09 871 8768
949 Allergies, other injuries & poisonings Both 0.1213 1.02 0.994,1.06 5269 26807 0.171 1.02 0.991,1.05 5154 26533
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.06457 1.1 0.995,1.22 419 4176 0.04571 1.11 1.0,1.23 412 4117
957 Injury to other and unspecified nerves injuries & poisonings Both 0.5916 1.05 0.871,1.27 116 1150 0.5433 1.06 0.876,1.29 114 1131
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.7063 0.988 0.928,1.05 1073 10721 0.1694 0.86 0.694,1.07 91 898
958.1 Postoperative shock injuries & poisonings Both 0.2455 0.899 0.752,1.08 133 1325 0.2692 0.903 0.753,1.08 129 1302
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.1892 0.867 0.701,1.07 92 911 0.1694 0.86 0.694,1.07 91 898
960 Poisoning by antibiotics injuries & poisonings Both 0.3681 1.02 0.976,1.07 2108 18753 0.1932 1.04 0.982,1.1 1368 13736
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.8433 0.984 0.836,1.16 158 1552 0.7638 0.974 0.821,1.16 142 1535
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.2065 1.04 0.981,1.09 1414 13864 0.1932 1.04 0.982,1.1 1368 13736
961 Poisoning by other anti-infectives injuries & poisonings Both 0.1062 1.08 0.984,1.18 470 4694 0.4416 0.973 0.909,1.04 912 9099
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.597 0.982 0.918,1.05 939 9190 0.4416 0.973 0.909,1.04 912 9099
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.0182 1.11 1.02,1.21 561 5601 0.2228 1.08 0.954,1.23 273 3003
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.1521 1.09 0.97,1.22 308 3069 0.2018 1.08 0.959,1.22 281 3031
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.1538 1.09 0.968,1.23 305 3029 0.2228 1.08 0.954,1.23 273 3003
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.9795 1.0 0.956,1.05 2031 19919 0.5715 0.986 0.94,1.03 1817 19322
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.9099 0.997 0.952,1.04 1980 19507 0.5715 0.986 0.94,1.03 1817 19322
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.3381 1.04 0.956,1.14 538 5360 0.1514 1.07 0.976,1.17 483 4999
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.1476 1.07 0.977,1.17 509 5070 0.1514 1.07 0.976,1.17 483 4999
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.07244 1.07 0.994,1.15 753 7525 0.9057 1.01 0.822,1.25 98 955
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.9572 1.0 0.946,1.06 1305 12848 0.9506 0.998 0.942,1.06 1262 12719
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.9016 1.01 0.823,1.25 98 967 0.9057 1.01 0.822,1.25 98 955
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.5715 0.938 0.752,1.17 86 850 0.3846 0.906 0.724,1.13 85 845
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.2818 1.04 0.971,1.11 1000 9986 0.4477 1.03 0.96,1.1 963 9898
969 Poisoning by psychotropic agents injuries & poisonings Both 0.7482 1.02 0.895,1.17 234 2331 0.9057 0.992 0.866,1.14 225 2306
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.8128 0.967 0.73,1.28 56 546 0.861 0.975 0.732,1.3 54 536
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.07413 1.13 0.988,1.3 228 2269 0.0389 1.26 1.01,1.56 86 849
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.04898 1.28 1.0,1.63 66 637 0.0631 1.27 0.988,1.63 62 620
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.04266 1.25 1.01,1.56 86 860 0.0389 1.26 1.01,1.56 86 849
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.3236 1.11 0.901,1.37 90 896 0.2291 1.14 0.919,1.43 82 882
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.2296 0.855 0.663,1.1 69 686 0.1493 0.825 0.636,1.07 66 682
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.2466 0.854 0.655,1.11 60 600 0.4036 0.891 0.679,1.17 56 596
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.1094 1.04 0.991,1.1 1565 14843 0.1483 1.04 0.986,1.1 1503 14701
979 Adverse drug events and drug allergies injuries & poisonings Both 0.863 1.0 0.96,1.05 2116 20636 0.9141 1.0 0.958,1.05 2027 20443
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.9931 0.999 0.812,1.23 91 904 0.826 0.977 0.791,1.21 88 890
990 Effects radiation NOS injuries & poisonings Both 0.4027 0.983 0.945,1.02 2707 23906 0.3459 0.981 0.942,1.02 2613 23589
994 Sepsis and SIRS injuries & poisonings Both 0.8453 1.0 0.956,1.06 1724 17160 0.7031 0.982 0.893,1.08 449 4768
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.5248 0.959 0.841,1.09 248 2472 0.6442 0.969 0.847,1.11 233 2440
994.2 Sepsis injuries & poisonings Both 0.7396 1.01 0.959,1.06 1636 16281 0.7031 0.982 0.893,1.08 449 4768
994.21 Septic shock injuries & poisonings Both 0.9057 1.01 0.918,1.1 484 4840 0.7031 0.982 0.893,1.08 449 4768
1000 Burns injuries & poisonings Both 0.8279 1.01 0.93,1.1 638 6350 0.8185 1.01 0.93,1.1 629 6276
1001 Foreign body injury injuries & poisonings Both 0.9078 0.998 0.956,1.04 2372 22762 0.9247 0.998 0.956,1.04 2308 22404
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.9183 1.0 0.972,1.03 4830 32603 0.8299 0.997 0.966,1.03 4683 32209
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.6622 1.01 0.954,1.08 1136 11344 0.8511 1.01 0.946,1.07 1106 11199
1005 Other symptoms injuries & poisonings Both 0.6412 1.01 0.981,1.03 7724 30626 0.5754 1.01 0.982,1.03 7536 30269
1006 Crushing injury injuries & poisonings Both 0.9268 0.994 0.871,1.13 245 2437 0.8531 0.988 0.864,1.13 241 2413
1007 Injury to blood vessels injuries & poisonings Both 0.6152 0.974 0.88,1.08 411 4106 0.5623 0.97 0.875,1.08 398 4037
1008 Crushing or internal injury to organs injuries & poisonings Both 0.561 0.98 0.916,1.05 934 9331 0.4375 0.973 0.909,1.04 910 9173
1009 Injury, NOS injuries & poisonings Both 0.6653 1.01 0.982,1.03 9284 29063 0.811 1.0 0.979,1.03 9093 28709
1010 Other tests injuries & poisonings Both 0.3311 0.99 0.97,1.01 19027 19331 0.2404 0.988 0.968,1.01 18625 19188
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.7362 1.0 0.977,1.03 5922 32336 0.7244 1.01 0.977,1.03 5776 31938
1012 Late effect injuries & poisonings Both 0.07586 0.935 0.868,1.01 792 7909 0.09772 0.939 0.871,1.01 782 7796
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.6501 1.01 0.969,1.05 2459 23709 0.6637 1.01 0.968,1.05 2342 23356
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.9226 1.01 0.865,1.17 177 1770 0.9016 1.01 0.866,1.18 173 1747
1015 Effects of other external causes injuries & poisonings Both 0.1358 1.02 0.993,1.05 5744 32595 0.2075 1.02 0.99,1.05 5601 32193
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.8185 0.995 0.952,1.04 2208 21537 0.6152 0.989 0.945,1.03 2119 21222
1100 Family history injuries & poisonings Both 0.1726 0.908 0.791,1.04 222 2220 0.2265 0.918 0.798,1.05 219 2196
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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