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MGI PRS for Nodular lymphoma(202.21) based on UKB GWAS (FINNGEN)
GWAS reference: !UKB_GWAS GWAS source: UKB GWAS (FINNGEN) PRS method: PRS-CS
PRSweb LD reference: eur GWAS phenotype: Follicular lymphoma PRSweb date: 2020-06-20
GWAS ID: C_FOLLICULAR_LYMPHOMA GWAS URL: http://www.nealelab.is/uk-biobank Genome build: GRCh37/hg19
PRS tuning parameter: PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.2042 1.03 0.985,1.07 2317 23065 0.1531 0.951 0.887,1.02 879 9023
008.5 Bacterial enteritis infectious diseases Both 0.9795 1.0 0.941,1.06 1090 10875 0.8185 0.992 0.924,1.06 826 8614
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.811 0.992 0.926,1.06 896 8939 0.8185 0.992 0.924,1.06 826 8614
008.6 Viral Enteritis infectious diseases Both 0.04375 1.09 1.0,1.19 590 5900 0.03041 1.1 1.01,1.2 556 5724
010 Tuberculosis infectious diseases Both 0.2118 1.1 0.947,1.28 195 1948 0.01774 1.03 1.0,1.05 18137 18913
031 Diseases due to other mycobacteria infectious diseases Both 0.4036 1.11 0.873,1.4 73 722 0.3119 1.13 0.888,1.45 68 700
038 Septicemia infectious diseases Both 0.07674 1.04 0.996,1.09 2043 20052 0.5395 1.02 0.953,1.1 866 9155
038.1 Gram negative septicemia infectious diseases Both 0.6053 0.974 0.883,1.07 459 4559 0.7464 0.983 0.888,1.09 426 4388
038.2 Gram positive septicemia infectious diseases Both 0.3162 0.927 0.798,1.08 184 1840 0.2559 0.913 0.781,1.07 168 1767
038.3 Bacteremia infectious diseases Both 0.2864 1.04 0.97,1.11 955 9489 0.5395 1.02 0.953,1.1 866 9155
041 Bacterial infection NOS infectious diseases Both 0.375 1.01 0.983,1.05 4641 32299 0.3499 0.936 0.816,1.07 212 2180
041.1 Staphylococcus infections infectious diseases Both 0.1413 1.04 0.986,1.1 1390 13828 0.5546 1.03 0.943,1.12 605 6159
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.4487 1.03 0.954,1.11 714 7071 0.4592 1.03 0.952,1.11 673 6859
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.5559 1.02 0.945,1.11 639 6376 0.5546 1.03 0.943,1.12 605 6159
041.2 Streptococcus infection infectious diseases Both 0.7889 1.01 0.952,1.07 1316 13131 0.9484 0.995 0.86,1.15 197 1965
041.21 Rheumatic fever / chorea infectious diseases Both 0.6823 0.971 0.841,1.12 205 2047 0.9484 0.995 0.86,1.15 197 1965
041.4 E. coli infectious diseases Both 0.3639 0.97 0.907,1.04 949 9462 0.3532 0.968 0.903,1.04 880 9132
041.8 H. pylori infectious diseases Both 0.05848 1.16 0.995,1.35 190 1892 0.06607 1.16 0.99,1.36 176 1831
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.5012 0.956 0.837,1.09 228 2265 0.3499 0.936 0.816,1.07 212 2180
053 Herpes zoster infectious diseases Both 0.9183 1.0 0.945,1.06 1184 11746 0.52 0.946 0.8,1.12 148 1583
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.5236 0.95 0.81,1.11 166 1655 0.52 0.946 0.8,1.12 148 1583
054 Herpes simplex infectious diseases Both 0.3899 1.03 0.968,1.09 1235 12278 0.4487 1.02 0.964,1.09 1173 11911
070 Viral hepatitis infectious diseases Both 0.877 0.994 0.918,1.08 661 6584 0.6531 0.984 0.918,1.05 869 8927
070.1 Viral hepatitis A infectious diseases Both 0.7499 1.04 0.816,1.33 67 660 0.9099 1.01 0.793,1.3 66 640
070.2 Viral hepatitis B infectious diseases Both 0.3126 0.924 0.792,1.08 162 1620 0.4315 0.938 0.8,1.1 152 1572
070.3 Viral hepatitis C infectious diseases Both 0.6577 0.978 0.887,1.08 439 4366 0.7762 0.986 0.892,1.09 418 4237
070.4 Chronic hepatitis infectious diseases Both 0.3606 0.928 0.791,1.09 161 1610 0.2455 0.906 0.767,1.07 148 1554
070.9 Hepatitis NOS infectious diseases Both 0.6266 0.983 0.919,1.05 924 9231 0.6531 0.984 0.918,1.05 869 8927
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.9572 0.995 0.827,1.2 122 1220 0.6012 0.945 0.763,1.17 90 928
071.1 HIV infection, symptomatic infectious diseases Both 0.5012 0.93 0.754,1.15 95 950 0.6012 0.945 0.763,1.17 90 928
078 Viral warts & HPV infectious diseases Both 0.6871 1.01 0.969,1.05 2651 24185 0.7943 1.01 0.965,1.05 2537 23472
079 Viral infection infectious diseases Both 0.1227 1.02 0.994,1.06 5061 29504 0.8375 1.01 0.926,1.1 561 5546
079.1 Varicella infection infectious diseases Both 0.3573 1.02 0.98,1.06 2940 25647 0.5662 1.01 0.972,1.05 2746 24841
079.2 Infectious mononucleosis infectious diseases Both 0.5129 1.05 0.911,1.2 213 2093 0.4395 1.06 0.917,1.22 202 2042
079.9 Viremia, NOS infectious diseases Both 0.8933 1.01 0.924,1.09 579 5713 0.8375 1.01 0.926,1.1 561 5546
080 Postoperative infection infectious diseases Both 0.5164 0.987 0.948,1.03 2586 25769 0.4764 0.985 0.945,1.03 2464 24866
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.8337 0.994 0.94,1.05 1364 13616 0.618 0.986 0.931,1.04 1287 13152
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.6902 1.02 0.94,1.1 700 6990 0.695 1.02 0.939,1.1 676 6793
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.879 1.0 0.962,1.05 2379 23308 0.2864 1.08 0.937,1.25 210 2157
110.1 Dermatophytosis infectious diseases Both 0.7943 1.01 0.962,1.05 2164 21163 0.9057 1.01 0.92,1.1 539 5492
110.11 Dermatophytosis of nail infectious diseases Both 0.865 0.995 0.939,1.05 1264 12489 0.7962 0.992 0.935,1.05 1206 12042
110.12 Althete's foot infectious diseases Both 0.2559 1.05 0.965,1.14 593 5884 0.3597 1.04 0.955,1.14 567 5676
110.13 Dermatophytosis of the body infectious diseases Both 0.6699 1.02 0.934,1.11 570 5682 0.9057 1.01 0.92,1.1 539 5492
110.2 Dermatomycoses infectious diseases Both 0.9977 1.0 0.886,1.13 283 2812 0.8872 0.991 0.876,1.12 273 2724
112 Candidiasis infectious diseases Both 0.06668 1.04 0.998,1.08 2931 25310 0.2786 1.05 0.96,1.15 522 5257
112.3 Candidiasis of skin and nails infectious diseases Both 0.1977 1.06 0.97,1.16 546 5450 0.2786 1.05 0.96,1.15 522 5257
117 Mycoses infectious diseases Both 0.2825 1.05 0.959,1.15 494 4925 0.3034 1.12 0.903,1.39 94 1024
117.1 Histoplasmosis infectious diseases Both 0.1409 0.836 0.658,1.06 66 660 0.1262 0.82 0.635,1.06 57 635
117.4 Aspergillosis infectious diseases Both 0.3467 1.1 0.899,1.35 105 1045 0.3034 1.12 0.903,1.39 94 1024
130 Spirochetal infection infectious diseases Both 0.455 0.931 0.771,1.12 118 1177 0.561 0.938 0.754,1.17 84 836
130.1 Lyme disease infectious diseases Both 0.4656 0.923 0.744,1.15 86 860 0.561 0.938 0.754,1.17 84 836
132 Infestation (lice, mites) infectious diseases Both 0.1416 1.13 0.959,1.34 146 1460 0.1726 1.13 0.95,1.33 140 1413
134 Helminthiases infectious diseases Both 0.4909 1.1 0.844,1.42 54 540 ,
136 Other infectious and parasitic diseases infectious diseases Both 0.2339 1.03 0.984,1.07 2438 24314 0.1837 1.03 0.986,1.07 2294 23467
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.9683 1.0 0.943,1.06 1166 11657 0.5559 1.02 0.958,1.08 1105 11219
145 Cancer of mouth neoplasms Both 0.5821 1.02 0.958,1.08 1182 11759 0.4055 1.07 0.912,1.26 162 1657
145.1 Cancer of lip neoplasms Both 0.6266 1.06 0.833,1.35 69 690 0.6368 1.06 0.823,1.37 62 671
145.2 Cancer of tongue neoplasms Both 0.08913 1.08 0.988,1.18 550 5486 0.1799 1.07 0.971,1.17 489 5296
145.3 Cancer of major salivary glands neoplasms Both 0.1146 0.909 0.807,1.02 310 3093 0.01762 0.86 0.759,0.974 283 2981
145.4 Cancer of the gums neoplasms Both 0.2559 1.1 0.932,1.31 143 1419 0.3556 1.09 0.912,1.29 132 1369
145.5 Cancer of the mouth floor neoplasms Both 0.2506 1.1 0.938,1.28 173 1723 0.4055 1.07 0.912,1.26 162 1657
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.3767 1.03 0.967,1.09 1124 11202 0.8185 1.02 0.878,1.18 189 1995
149.1 Cancer of oropharynx neoplasms Both 0.006531 1.18 1.05,1.33 291 2892 0.01538 1.17 1.03,1.33 254 2773
149.2 Cancer of nasopharynx neoplasms Both 0.5035 1.08 0.866,1.34 87 855 0.7031 0.953 0.746,1.22 68 826
149.3 Cancer of hypopharynx neoplasms Both 0.278 1.15 0.895,1.47 68 680 0.5236 1.09 0.835,1.42 59 654
149.4 Cancer of larynx neoplasms Both 0.7244 0.98 0.877,1.1 332 3314 0.6026 0.97 0.863,1.09 303 3184
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.1045 1.08 0.985,1.18 505 5041 0.2065 1.06 0.966,1.17 430 4842
149.9 Cancer of of nasal cavities neoplasms Both 0.5848 1.04 0.903,1.2 208 2067 0.8185 1.02 0.878,1.18 189 1995
150 Cancer of esophagus neoplasms Both 0.4624 1.04 0.936,1.16 378 3776 0.8072 1.01 0.907,1.13 340 3658
151 Cancer of stomach neoplasms Both 0.1637 1.07 0.972,1.18 430 4292 0.4966 1.04 0.926,1.17 293 4169
153 Colorectal cancer neoplasms Both 0.5035 1.02 0.962,1.08 1196 11882 0.1698 1.06 0.976,1.15 622 6456
153.2 Colon cancer neoplasms Both 0.673 1.01 0.949,1.08 941 9327 0.6668 1.02 0.946,1.09 846 9044
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.1288 1.06 0.982,1.15 669 6663 0.1698 1.06 0.976,1.15 622 6456
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.8185 0.988 0.893,1.09 418 4180 0.3917 0.945 0.831,1.08 256 2775
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.413 0.95 0.841,1.07 285 2850 0.3917 0.945 0.831,1.08 256 2775
157 Pancreatic cancer neoplasms Both 0.1524 1.08 0.973,1.19 430 4292 0.5834 1.03 0.925,1.15 369 4185
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.5649 1.02 0.961,1.07 1369 13455 0.7482 1.01 0.952,1.07 1226 13083
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.08531 1.07 0.991,1.15 779 7785 0.2203 1.09 0.95,1.25 225 2485
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.9795 0.998 0.856,1.16 183 1830 0.6531 0.958 0.796,1.15 121 1784
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.1387 1.14 0.958,1.36 133 1330 0.3631 1.09 0.907,1.31 122 1301
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.2588 1.08 0.947,1.23 255 2550 0.2203 1.09 0.95,1.25 225 2485
164 Cancer of intrathoracic organs neoplasms Both 0.7691 0.972 0.804,1.18 111 1110 0.9977 1.0 0.814,1.23 92 1078
165 Cancer within the respiratory system neoplasms Both 0.06067 1.07 0.997,1.14 945 9436 0.1694 1.05 0.978,1.14 731 8414
165.1 Cancer of bronchus; lung neoplasms Both 0.1016 1.06 0.989,1.14 874 8724 0.1694 1.05 0.978,1.14 731 8414
170 Cancer of bone and connective tissue neoplasms Both 0.1496 1.04 0.986,1.09 1538 15304 0.6607 1.01 0.95,1.08 961 10557
170.1 Bone cancer neoplasms Both 0.1977 1.05 0.973,1.14 668 6660 0.1016 1.07 0.986,1.17 584 6423
170.2 Cancer of connective tissue neoplasms Both 0.7834 1.01 0.948,1.07 1097 10941 0.6607 1.01 0.95,1.08 961 10557
172 Skin cancer neoplasms Both 0.5508 0.992 0.965,1.02 7099 27878 0.7063 1.01 0.951,1.08 1113 9928
172.1 Melanomas of skin, dx or hx neoplasms Both 0.1274 0.969 0.931,1.01 2701 21867 0.2014 0.973 0.933,1.01 2449 20882
172.11 Melanomas of skin neoplasms Both 0.1161 0.968 0.929,1.01 2624 21526 0.2014 0.973 0.933,1.01 2449 20882
172.2 Other non-epithelial cancer of skin neoplasms Both 0.9016 0.998 0.969,1.03 5888 25669 0.5212 1.02 0.967,1.07 1756 14121
172.21 Basal cell carcinoma neoplasms Both 0.6397 1.01 0.971,1.05 2988 20068 0.7379 1.01 0.967,1.05 2807 19441
172.22 Squamous cell carcinoma neoplasms Both 0.2748 1.03 0.979,1.08 1917 14585 0.5212 1.02 0.967,1.07 1756 14121
172.3 Carcinoma in situ of skin neoplasms Both 0.5058 1.02 0.961,1.08 1215 10290 0.7063 1.01 0.951,1.08 1113 9928
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.8128 1.01 0.955,1.06 1575 15093 0.8185 0.994 0.942,1.05 1472 14606
174 Breast cancer neoplasms Both 0.5546 1.01 0.971,1.06 2694 13131 0.5023 1.05 0.908,1.22 187 1998
174.1 Breast cancer [female] neoplasms Female 0.673 1.01 0.967,1.05 2605 12548 0.7551 1.01 0.963,1.05 2343 12228
174.11 Malignant neoplasm of female breast neoplasms Female 0.6887 1.01 0.966,1.05 2565 12510 0.7551 1.01 0.963,1.05 2343 12228
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.4285 1.06 0.92,1.22 206 2051 0.5023 1.05 0.908,1.22 187 1998
175 Acquired absence of breast neoplasms Female 0.5534 1.02 0.955,1.09 978 9172 0.8017 1.01 0.941,1.08 868 8968
180 Cervical cancer and dysplasia neoplasms Female 0.4699 0.978 0.921,1.04 1182 10494 0.877 0.994 0.925,1.07 829 7749
180.1 Cervical cancer neoplasms Female 0.5058 0.967 0.877,1.07 430 4300 0.5 0.966 0.874,1.07 410 4191
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.8128 0.991 0.924,1.06 857 7886 0.877 0.994 0.925,1.07 829 7749
182 Malignant neoplasm of uterus neoplasms Female 0.3963 0.966 0.891,1.05 643 6390 0.2877 0.956 0.881,1.04 613 6202
184 Cancer of other female genital organs neoplasms Female 0.9484 1.0 0.936,1.07 910 8957 0.5236 1.03 0.939,1.13 497 5112
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.798 1.01 0.923,1.11 491 4888 0.879 0.991 0.889,1.11 345 3559
184.11 Malignant neoplasm of ovary neoplasms Female 0.7295 0.981 0.883,1.09 367 3659 0.879 0.991 0.889,1.11 345 3559
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.3126 1.05 0.957,1.15 526 5253 0.5236 1.03 0.939,1.13 497 5112
185 Cancer of prostate neoplasms Male 0.413 0.98 0.935,1.03 2432 8825 0.4305 0.981 0.935,1.03 2323 8483
187 Cancer of other male genital organs neoplasms Male 0.6998 0.976 0.864,1.1 276 2723 0.5483 0.948 0.797,1.13 136 1335
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.6138 1.06 0.856,1.3 96 960 0.6622 1.05 0.842,1.31 85 917
187.2 Malignant neoplasm of testis neoplasms Male 0.6776 0.965 0.814,1.14 144 1387 0.5483 0.948 0.797,1.13 136 1335
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.2564 1.02 0.983,1.07 2552 20553 0.6209 1.02 0.938,1.11 570 5570
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.208 1.04 0.98,1.1 1261 12588 0.7603 0.977 0.84,1.14 187 1916
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.673 1.01 0.953,1.08 1083 10823 0.743 1.01 0.948,1.08 1027 10403
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.6457 0.967 0.837,1.12 202 2010 0.7603 0.977 0.84,1.14 187 1916
189.2 Cancer of bladder neoplasms Both 0.4742 1.02 0.967,1.07 1575 13516 0.7129 1.01 0.956,1.07 1387 12064
189.21 Malignant neoplasm of bladder neoplasms Both 0.7396 1.01 0.956,1.07 1456 12558 0.7129 1.01 0.956,1.07 1387 12064
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.7962 1.01 0.93,1.1 601 5841 0.6209 1.02 0.938,1.11 570 5570
190 Cancer of eye neoplasms Both 0.3837 0.919 0.759,1.11 114 1125 0.3758 0.913 0.747,1.12 102 1073
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.1932 1.05 0.977,1.12 904 9040 0.3556 1.05 0.95,1.15 444 4670
191.1 Cancer of brain and nervous system neoplasms Both 0.151 1.07 0.977,1.16 580 5800 0.3556 1.05 0.95,1.15 444 4670
191.11 Cancer of brain neoplasms Both 0.3214 1.05 0.955,1.15 483 4830 0.3556 1.05 0.95,1.15 444 4670
193 Thyroid cancer neoplasms Both 0.5662 0.979 0.91,1.05 798 7953 0.4325 0.97 0.898,1.05 711 7716
194 Cancer of other endocrine glands neoplasms Both 0.1309 0.898 0.782,1.03 221 2207 0.2805 0.923 0.798,1.07 199 2126
195 Cancer, suspected or other neoplasms Both 0.5821 1.01 0.983,1.03 12134 23141 0.7244 1.01 0.944,1.09 846 8906
195.1 Malignant neoplasm, other neoplasms Both 0.8017 1.0 0.98,1.03 11693 23098 0.7691 0.996 0.972,1.02 10662 22967
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.3133 1.03 0.968,1.1 970 8963 0.7244 1.01 0.944,1.09 846 8906
196 Radiotherapy neoplasms Both 0.7691 1.01 0.961,1.05 2067 15612 0.8511 0.995 0.947,1.05 1773 15509
197 Chemotherapy neoplasms Both 0.05152 1.03 1.0,1.07 4051 21210 0.1346 1.03 0.991,1.07 3399 21081
198 Secondary malignant neoplasm neoplasms Both 0.2818 1.02 0.986,1.05 4986 21474 0.009863 1.19 1.04,1.35 239 2733
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.2323 1.02 0.985,1.06 3156 19844 0.3266 1.02 0.98,1.06 2747 19725
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.02685 1.08 1.01,1.16 903 8847 0.03954 1.08 1.0,1.16 781 8787
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.8913 1.01 0.932,1.08 725 7166 0.7534 0.987 0.911,1.07 640 7115
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.7834 1.01 0.932,1.1 643 6395 0.7261 1.02 0.93,1.11 539 6354
198.5 Secondary malignancy of brain/spine neoplasms Both 0.5649 1.03 0.939,1.12 545 5421 0.1995 1.06 0.968,1.17 467 5384
198.6 Secondary malignancy of bone neoplasms Both 0.5058 1.03 0.95,1.11 712 6962 0.7447 1.01 0.933,1.1 601 6911
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.003936 1.19 1.06,1.34 287 2752 0.009863 1.19 1.04,1.35 239 2733
199 Neoplasm of uncertain behavior neoplasms Both 0.01959 1.04 1.01,1.07 4947 22823 0.4467 1.1 0.863,1.4 69 716
199.4 Neurofibromatosis neoplasms Both 0.3342 1.12 0.887,1.42 72 720 0.4467 1.1 0.863,1.4 69 716
200 Myeloproliferative disease neoplasms Both 0.2223 1.04 0.974,1.12 886 8851 0.9333 1.01 0.851,1.19 146 1610
200.1 Polycythemia vera neoplasms Both 0.6966 1.03 0.879,1.21 161 1610 0.9333 1.01 0.851,1.19 146 1610
201 Hodgkin's disease neoplasms Both 0.7244 1.03 0.87,1.22 138 1373 ,
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.03273 1.06 1.01,1.13 1308 13070 ,
202.2 Non-Hodgkins lymphoma neoplasms Both 0.1079 1.05 0.989,1.12 1141 11402 ,
202.21 Nodular lymphoma neoplasms Both 0.1489 1.06 0.979,1.15 632 6320 ,
202.22 Reticulosarcoma neoplasms Both 0.5117 1.06 0.89,1.26 137 1355 ,
202.24 Large cell lymphoma neoplasms Both 0.413 1.08 0.898,1.3 132 1300 ,
204 Leukemia neoplasms Both 0.003013 1.14 1.05,1.25 545 5450 0.09931 1.16 0.973,1.37 139 1795
204.1 Lymphoid leukemia neoplasms Both 0.9162 1.01 0.867,1.17 187 1870 0.2838 1.14 0.894,1.46 69 1350
204.11 Lymphoid leukemia, acute neoplasms Both 0.4335 0.902 0.697,1.17 58 580 ,
204.12 Lymphoid leukemia, chronic neoplasms Both 0.6486 1.04 0.871,1.25 136 1350 0.2838 1.14 0.894,1.46 69 1350
204.2 Myeloid leukemia neoplasms Both 0.04276 1.16 1.0,1.33 206 2060 0.03097 1.27 1.02,1.57 87 1240
204.21 Myeloid leukemia, acute neoplasms Both 0.002032 1.34 1.11,1.61 124 1240 0.03097 1.27 1.02,1.57 87 1240
204.4 Multiple myeloma neoplasms Both 0.09931 1.14 0.976,1.33 180 1795 0.09931 1.16 0.973,1.37 139 1795
208 Benign neoplasm of colon neoplasms Both 0.2291 1.02 0.99,1.04 8098 29324 0.2786 1.01 0.989,1.04 7634 28513
209 Neuroendocrine tumors neoplasms Both 0.52 1.05 0.911,1.2 222 2220 0.7551 1.03 0.854,1.24 114 2128
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.912 1.0 0.953,1.06 1584 15798 0.9162 1.0 0.951,1.06 1481 15309
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.1493 1.02 0.993,1.05 5807 30296 0.2042 1.02 0.99,1.05 5477 29525
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.7674 0.992 0.942,1.05 1556 15533 0.6966 0.989 0.937,1.04 1420 14987
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.6966 1.01 0.957,1.07 1405 13304 0.6577 1.01 0.957,1.07 1324 13057
214 Lipoma neoplasms Both 0.9908 1.0 0.941,1.06 1117 11124 0.7943 0.989 0.911,1.07 638 6571
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.6745 0.983 0.908,1.06 681 6793 0.7943 0.989 0.911,1.07 638 6571
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.5212 1.01 0.977,1.05 3594 32904 0.7015 1.01 0.972,1.04 3374 31891
216 Benign neoplasm of skin neoplasms Both 0.8872 1.0 0.978,1.03 9073 29036 0.8933 1.01 0.828,1.24 107 1065
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.8166 1.02 0.839,1.25 111 1093 0.8933 1.01 0.828,1.24 107 1065
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.5082 0.98 0.922,1.04 1150 11417 0.5902 0.982 0.92,1.05 1007 10202
217.1 Nevus, non-neoplastic neoplasms Both 0.975 0.999 0.938,1.06 1063 10579 0.5902 0.982 0.92,1.05 1007 10202
218 Benign neoplasm of uterus neoplasms Female 0.5768 1.01 0.974,1.05 3552 13845 0.9183 1.0 0.962,1.04 2722 13316
218.1 Uterine leiomyoma neoplasms Female 0.113 1.04 0.99,1.1 1506 13465 0.1652 1.04 0.984,1.1 1443 13082
218.2 Other benign neoplasm of uterus neoplasms Female 0.877 1.0 0.963,1.04 2824 13698 0.9183 1.0 0.962,1.04 2722 13316
220 Benign neoplasm of ovary neoplasms Female 0.6324 0.982 0.911,1.06 763 7571 0.5508 0.977 0.906,1.05 738 7406
221 Benign neoplasm of other female genital organs neoplasms Female 0.2917 0.973 0.925,1.02 1666 12074 0.2312 0.969 0.92,1.02 1614 11796
222 Benign neoplasm of male genital organs neoplasms Male 0.5675 1.02 0.954,1.09 954 9116 0.6966 1.01 0.947,1.09 913 8729
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.228 1.03 0.98,1.09 1547 11080 0.3443 1.03 0.972,1.08 1492 10843
224 Benign neoplasm of eye neoplasms Both 0.263 1.05 0.962,1.15 511 5062 0.0514 1.11 0.999,1.23 393 4060
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.06012 1.1 0.996,1.21 429 4230 0.0514 1.11 0.999,1.23 393 4060
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.8279 1.01 0.945,1.07 1039 10379 0.191 1.1 0.954,1.27 198 2319
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.8091 0.991 0.922,1.06 817 8160 0.7691 0.989 0.919,1.06 783 7861
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.227 1.08 0.951,1.24 242 2420 0.191 1.1 0.954,1.27 198 2319
226 Benign neoplasm of thyroid glands neoplasms Both 0.1656 1.05 0.982,1.11 1082 10810 0.3034 1.03 0.97,1.1 1023 10432
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.1726 1.04 0.983,1.1 1387 13870 0.9078 0.994 0.889,1.11 359 3598
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.8091 0.987 0.889,1.1 375 3745 0.9954 1.0 0.898,1.11 360 3623
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.04943 1.08 1.0,1.18 644 6434 0.03981 1.09 1.0,1.18 633 6233
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.9376 0.996 0.893,1.11 373 3724 0.9078 0.994 0.889,1.11 359 3598
228 Hemangioma and lymphangioma, any site neoplasms Both 0.2661 0.97 0.92,1.02 1517 15150 0.7907 0.99 0.92,1.07 794 8155
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.9795 0.999 0.931,1.07 849 8478 0.7907 0.99 0.92,1.07 794 8155
229 Benign neoplasm of unspecified sites neoplasms Both 0.7178 0.995 0.969,1.02 6631 31223 0.867 0.997 0.967,1.03 4622 28818
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.9099 1.0 0.972,1.03 4904 29712 0.867 0.997 0.967,1.03 4622 28818
860 Bone marrow or stem cell transplant neoplasms Both 0.5794 1.05 0.876,1.27 127 1266 0.4613 1.1 0.858,1.4 67 1228
240 Simple and unspecified goiter endocrine/metabolic Both 0.7278 1.01 0.941,1.09 767 7647 0.9638 1.0 0.928,1.08 724 7416
241 Nontoxic nodular goiter endocrine/metabolic Both 0.2931 1.02 0.98,1.07 2274 18240 0.5093 0.978 0.915,1.05 958 9764
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.2477 1.03 0.98,1.08 1795 16440 0.5284 1.02 0.966,1.07 1667 15967
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.7063 0.988 0.926,1.05 1017 10065 0.5093 0.978 0.915,1.05 958 9764
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.8091 0.992 0.932,1.06 1075 10635 0.6012 0.949 0.78,1.15 113 1122
242.1 Graves' disease endocrine/metabolic Both 0.2547 0.941 0.847,1.05 399 3965 0.3221 0.947 0.851,1.05 384 3855
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.5702 1.06 0.86,1.31 98 978 0.9594 1.01 0.807,1.25 91 958
242.3 Exophthalmos endocrine/metabolic Both 0.6442 1.03 0.904,1.18 245 2447 0.6012 0.949 0.78,1.15 113 1122
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.5781 0.947 0.781,1.15 116 1160 0.6012 0.949 0.78,1.15 113 1122
244 Hypothyroidism endocrine/metabolic Both 0.02028 1.03 1.01,1.06 6448 27183 0.05012 1.03 1.0,1.06 5647 25926
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.7112 1.01 0.957,1.07 1421 14153 0.743 1.01 0.954,1.07 1297 13732
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.1 1.06 0.989,1.14 853 8502 0.16 1.05 0.98,1.13 793 8238
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.01766 1.04 1.01,1.07 5996 26719 0.05012 1.03 1.0,1.06 5647 25926
245 Thyroiditis endocrine/metabolic Both 0.3656 1.04 0.955,1.13 574 5720 0.863 1.01 0.914,1.11 435 4430
245.2 Chronic thyroiditis endocrine/metabolic Both 0.5035 1.03 0.939,1.14 463 4617 0.863 1.01 0.914,1.11 435 4430
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.6607 1.02 0.928,1.13 456 4533 0.863 1.01 0.914,1.11 435 4430
246 Other disorders of thyroid endocrine/metabolic Both 0.08222 1.03 0.996,1.06 5018 25158 0.2193 1.06 0.967,1.15 532 5484
246.2 Thyroid cyst endocrine/metabolic Both 0.09772 0.828 0.662,1.04 83 804 0.06561 0.806 0.641,1.01 78 784
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.2254 1.05 0.968,1.15 568 5651 0.2193 1.06 0.967,1.15 532 5484
249 Secondary diabetes mellitus endocrine/metabolic Both 0.5957 1.02 0.944,1.1 686 6849 0.4093 1.03 0.954,1.12 638 6591
250 Diabetes mellitus endocrine/metabolic Both 0.06622 1.02 0.999,1.05 10115 27568 0.1694 1.05 0.978,1.13 783 7865
250.1 Type 1 diabetes endocrine/metabolic Both 0.3097 0.968 0.908,1.03 1053 10521 0.3357 0.884 0.688,1.14 66 670
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.08551 0.825 0.662,1.03 80 792 0.05559 0.8 0.636,1.01 74 770
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.6577 0.97 0.849,1.11 235 2346 0.8433 0.986 0.86,1.13 223 2262
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.2761 0.933 0.824,1.06 280 2800 0.3436 0.94 0.828,1.07 264 2702
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.2018 0.915 0.799,1.05 238 2372 0.2512 0.922 0.804,1.06 229 2294
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.271 0.872 0.683,1.11 70 690 0.3357 0.884 0.688,1.14 66 670
250.2 Type 2 diabetes endocrine/metabolic Both 0.2667 1.02 0.988,1.04 7035 26169 0.875 0.993 0.905,1.09 484 4862
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.9772 0.997 0.828,1.2 120 1200 0.7413 0.968 0.799,1.17 113 1164
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.6095 1.02 0.956,1.08 1133 11056 0.6039 1.02 0.955,1.08 1081 10635
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.2606 1.04 0.97,1.12 826 8208 0.2104 1.05 0.974,1.13 789 7900
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.9016 1.0 0.95,1.06 1419 13969 0.8531 1.01 0.951,1.06 1346 13435
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.8933 1.01 0.92,1.1 513 5077 0.875 0.993 0.905,1.09 484 4862
250.3 Insulin pump user endocrine/metabolic Both 0.2328 1.03 0.982,1.08 1884 17814 0.2506 1.03 0.98,1.08 1792 17163
250.4 Abnormal glucose endocrine/metabolic Both 0.01633 1.04 1.01,1.07 5404 26451 0.005572 1.05 1.01,1.08 4481 25062
250.41 Impaired fasting glucose endocrine/metabolic Both 0.4467 1.02 0.966,1.08 1326 13130 0.5649 1.02 0.96,1.08 1261 12660
250.42 Other abnormal glucose endocrine/metabolic Both 0.00695 1.04 1.01,1.08 4736 25883 0.005572 1.05 1.01,1.08 4481 25062
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.5916 0.94 0.749,1.18 78 747 0.5093 0.925 0.734,1.17 75 735
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.8337 0.994 0.935,1.06 1137 11335 0.8279 0.993 0.933,1.06 1076 10910
250.7 Diabetic retinopathy endocrine/metabolic Both 0.2104 1.05 0.974,1.13 821 8168 0.1694 1.05 0.978,1.13 783 7865
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.8453 1.01 0.928,1.1 595 5901 0.2366 1.05 0.969,1.13 666 6781
251.1 Hypoglycemia endocrine/metabolic Both 0.2254 1.05 0.971,1.13 702 7015 0.2366 1.05 0.969,1.13 666 6781
252 Disorders of parathyroid gland endocrine/metabolic Both 0.1033 1.04 0.992,1.09 1807 17879 0.1982 1.07 0.965,1.19 380 3808
252.1 Hyperparathyroidism endocrine/metabolic Both 0.182 1.03 0.984,1.09 1656 16459 0.138 1.04 0.988,1.09 1593 15901
252.2 Hypoparathyroidism endocrine/metabolic Both 0.1656 1.07 0.971,1.19 393 3922 0.1982 1.07 0.965,1.19 380 3808
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.6902 0.984 0.91,1.06 691 6893 0.859 1.02 0.819,1.27 84 886
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.1963 0.91 0.788,1.05 205 2041 0.02109 0.75 0.587,0.958 72 701
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.02244 0.752 0.589,0.96 72 720 0.02109 0.75 0.587,0.958 72 701
253.2 Pituitary hypofunction endocrine/metabolic Both 0.7112 0.972 0.836,1.13 184 1840 0.9616 0.996 0.853,1.16 172 1783
253.3 Diabetes insipidus endocrine/metabolic Both 0.2704 1.14 0.9,1.46 70 694 0.1236 1.22 0.947,1.57 63 676
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.4677 0.92 0.736,1.15 92 899 0.1629 0.845 0.668,1.07 84 867
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.7096 1.04 0.844,1.28 93 925 0.859 1.02 0.819,1.27 84 886
255 Disorders of adrenal glands endocrine/metabolic Both 0.2443 0.965 0.909,1.02 1186 11860 0.125 0.924 0.834,1.02 414 4358
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.2 0.925 0.822,1.04 290 2886 0.1476 0.862 0.704,1.05 104 1030
255.11 Cushing's syndrome endocrine/metabolic Both 0.6699 0.964 0.814,1.14 144 1440 0.4436 0.934 0.784,1.11 135 1393
255.12 Hyperaldosteronism endocrine/metabolic Both 0.1102 0.849 0.695,1.04 106 1057 0.1476 0.862 0.704,1.05 104 1030
255.2 Adrenal hypofunction endocrine/metabolic Both 0.1622 0.935 0.851,1.03 477 4758 0.125 0.924 0.834,1.02 414 4358
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.07568 0.916 0.831,1.01 451 4496 0.125 0.924 0.834,1.02 414 4358
256 Ovarian dysfunction endocrine/metabolic Female 0.1766 0.953 0.888,1.02 859 8184 0.6871 0.982 0.899,1.07 540 5351
256.4 Polycystic ovaries endocrine/metabolic Female 0.787 0.988 0.905,1.08 544 5436 0.6871 0.982 0.899,1.07 540 5351
257 Testicular dysfunction endocrine/metabolic Male 0.3733 1.04 0.959,1.12 747 7455 0.4305 1.03 0.954,1.12 680 6965
257.1 Testicular hypofunction endocrine/metabolic Male 0.5495 1.02 0.948,1.11 725 7234 0.4305 1.03 0.954,1.12 680 6965
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.06397 1.27 0.986,1.63 66 660 0.3524 0.904 0.73,1.12 88 896
258.1 Postablative ovarian failure endocrine/metabolic Female 0.3396 0.903 0.733,1.11 92 920 0.3524 0.904 0.73,1.12 88 896
259 Other endocrine disorders endocrine/metabolic Both 0.9162 0.996 0.924,1.07 759 7562 0.9772 1.0 0.927,1.08 711 7334
260 Protein-calorie malnutrition endocrine/metabolic Both 0.7834 1.01 0.964,1.05 2353 22279 0.9311 0.996 0.916,1.08 598 6479
260.1 Cachexia endocrine/metabolic Both 0.7228 0.977 0.857,1.11 239 2388 0.561 0.959 0.833,1.1 205 2316
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.6324 1.01 0.959,1.07 1363 13589 0.3327 0.949 0.853,1.06 357 3997
260.22 Nutritional marasmus endocrine/metabolic Both 0.182 0.934 0.846,1.03 413 4130 0.3327 0.949 0.853,1.06 357 3997
260.3 Adult failure to thrive endocrine/metabolic Both 0.06397 0.918 0.838,1.0 509 5051 0.104 0.924 0.84,1.02 456 4859
260.6 Anorexia endocrine/metabolic Both 0.6109 1.02 0.943,1.1 677 6722 0.9311 0.996 0.916,1.08 598 6479
261 Vitamin deficiency endocrine/metabolic Both 0.03972 1.03 1.0,1.06 5614 30157 0.0208 1.04 1.01,1.07 5024 29025
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.6792 1.02 0.939,1.1 649 6482 0.7145 1.02 0.935,1.1 611 6248
261.4 Vitamin D deficiency endocrine/metabolic Both 0.0456 1.03 1.0,1.06 5264 29859 0.0208 1.04 1.01,1.07 5024 29025
262 Mineral deficiency NEC endocrine/metabolic Both 0.7211 1.01 0.944,1.09 854 8532 0.6966 1.01 0.944,1.09 803 8280
263 Other nutritional deficiency endocrine/metabolic Both 0.9441 0.996 0.901,1.1 412 4113 0.975 1.0 0.903,1.11 387 3978
264 Lack of normal physiological development endocrine/metabolic Both 0.9354 1.01 0.86,1.18 175 1735 0.9572 1.01 0.764,1.33 58 599
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.875 1.02 0.826,1.25 95 950 0.9099 0.988 0.793,1.23 85 923
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.9333 0.989 0.756,1.29 61 607 0.9572 1.01 0.764,1.33 58 599
269 Proteinuria endocrine/metabolic Both 0.9016 0.996 0.935,1.06 1079 10768 0.975 0.999 0.936,1.07 1020 10398
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.5689 1.02 0.948,1.1 740 7378 0.05534 1.16 0.997,1.35 194 2103
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.3055 0.91 0.759,1.09 129 1283 0.5383 0.935 0.756,1.16 97 963
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.2931 0.894 0.725,1.1 101 998 0.5383 0.935 0.756,1.16 97 963
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.1535 1.18 0.941,1.47 81 810 0.07762 1.23 0.977,1.56 73 774
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.5559 1.03 0.941,1.12 560 5581 0.05534 1.16 0.997,1.35 194 2103
270.32 Paraproteinemia endocrine/metabolic Both 0.8414 1.01 0.9,1.14 301 2982 0.7943 0.983 0.867,1.12 261 2860
270.33 Amyloidosis endocrine/metabolic Both 0.3296 1.14 0.876,1.48 55 550 0.4786 1.1 0.84,1.45 51 526
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.07943 1.14 0.985,1.31 218 2178 0.05534 1.16 0.997,1.35 194 2103
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.01132 1.06 1.01,1.11 1952 19491 0.5689 1.07 0.851,1.34 77 784
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.0317 1.05 1.0,1.1 1885 18823 0.04305 1.05 1.0,1.1 1819 18101
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.6397 1.05 0.844,1.32 81 810 0.5689 1.07 0.851,1.34 77 784
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.01521 1.03 1.01,1.05 14793 22696 0.06714 0.878 0.763,1.01 228 2338
272.1 Hyperlipidemia endocrine/metabolic Both 0.0171 1.03 1.0,1.05 14763 22682 0.1303 1.04 0.99,1.08 2160 14918
272.11 Hypercholesterolemia endocrine/metabolic Both 0.01963 1.04 1.01,1.08 4668 18640 0.0415 1.04 1.0,1.07 4443 17998
272.12 Hyperglyceridemia endocrine/metabolic Both 0.6871 1.01 0.948,1.08 945 9395 0.8035 1.01 0.943,1.08 915 9035
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.06561 1.04 0.997,1.09 2272 15492 0.1303 1.04 0.99,1.08 2160 14918
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.1663 0.909 0.795,1.04 244 2425 0.06714 0.878 0.763,1.01 228 2338
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.6745 1.01 0.964,1.06 1971 18337 0.7691 0.974 0.815,1.16 135 1310
274.1 Gout endocrine/metabolic Both 0.8872 1.0 0.957,1.05 1879 17712 0.6039 0.98 0.91,1.06 753 7583
274.11 Gouty arthropathy endocrine/metabolic Both 0.869 0.994 0.925,1.07 793 7891 0.6039 0.98 0.91,1.06 753 7583
274.2 Crystal arthropathies endocrine/metabolic Both 0.6871 1.04 0.872,1.23 146 1425 0.7691 0.974 0.815,1.16 135 1310
274.21 Chondrocalcinosis endocrine/metabolic Both 0.8933 1.01 0.85,1.2 140 1363 0.7691 0.974 0.815,1.16 135 1310
275 Disorders of mineral metabolism endocrine/metabolic Both 0.03673 1.04 1.0,1.08 3252 30253 0.006998 1.4 1.1,1.79 67 681
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.6714 1.02 0.946,1.09 845 8441 0.8433 1.01 0.935,1.09 756 8138
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.04571 1.04 1.0,1.09 2502 24757 0.2128 1.04 0.976,1.12 938 9850
275.51 Hypocalcemia endocrine/metabolic Both 0.1592 1.06 0.979,1.14 722 7203 0.1694 1.06 0.977,1.14 671 6955
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.2911 1.03 0.971,1.1 1024 10193 0.2128 1.04 0.976,1.12 938 9850
275.6 Hypercalcemia endocrine/metabolic Both 0.04592 1.07 1.0,1.14 1043 10415 0.03319 1.07 1.01,1.15 975 10056
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.004406 1.04 1.01,1.07 7227 30901 0.052 0.808 0.651,1.0 94 973
276.1 Electrolyte imbalance endocrine/metabolic Both 0.003793 1.05 1.01,1.08 4833 28673 0.3273 1.03 0.974,1.08 1476 15710
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.9162 1.01 0.91,1.11 415 4115 0.984 0.999 0.901,1.11 388 3991
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.02109 1.06 1.01,1.11 1857 17982 0.03311 1.06 1.0,1.11 1706 17439
276.13 Hyperpotassemia endocrine/metabolic Both 0.207 1.03 0.984,1.07 2238 20576 0.4121 1.02 0.974,1.07 2067 19969
276.14 Hypopotassemia endocrine/metabolic Both 0.227 1.03 0.981,1.09 1626 16160 0.3273 1.03 0.974,1.08 1476 15710
276.4 Acid-base balance disorder endocrine/metabolic Both 0.4943 1.02 0.967,1.07 1593 15855 0.7603 1.02 0.906,1.14 320 3398
276.41 Acidosis endocrine/metabolic Both 0.6808 1.01 0.957,1.07 1357 13508 0.6745 1.01 0.956,1.07 1259 13134
276.42 Alkalosis endocrine/metabolic Both 0.414 1.05 0.937,1.17 350 3498 0.7603 1.02 0.906,1.14 320 3398
276.5 Hypovolemia endocrine/metabolic Both 0.01127 1.05 1.01,1.08 3615 28901 0.01021 1.05 1.01,1.09 3290 28153
276.6 Fluid overload endocrine/metabolic Both 0.8185 1.01 0.945,1.07 1046 10404 0.984 1.0 0.937,1.07 958 10084
276.8 Polydipsia endocrine/metabolic Both 0.05984 0.817 0.661,1.01 99 990 0.052 0.808 0.651,1.0 94 973
277 Other disorders of metabolism endocrine/metabolic Both 0.2547 1.03 0.978,1.09 1534 15324 0.4416 1.03 0.95,1.12 589 5884
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.0778 1.12 0.987,1.28 252 2520 0.1327 1.11 0.969,1.27 226 2432
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.6561 1.02 0.935,1.11 547 5456 0.5715 1.03 0.937,1.12 499 5275
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.6138 1.02 0.943,1.11 675 6743 0.9977 1.0 0.915,1.09 544 5466
277.51 Lipoprotein disorders endocrine/metabolic Both 0.7925 1.01 0.928,1.1 567 5665 0.9977 1.0 0.915,1.09 544 5466
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.5023 1.03 0.947,1.12 610 6090 0.4416 1.03 0.95,1.12 589 5884
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.1858 1.01 0.993,1.04 15130 23191 0.004446 1.08 1.02,1.14 1457 13264
278.1 Obesity endocrine/metabolic Both 0.5 1.01 0.986,1.03 13507 23193 0.8204 1.0 0.975,1.03 6175 22368
278.11 Morbid obesity endocrine/metabolic Both 0.8974 1.0 0.974,1.03 6376 23143 0.8204 1.0 0.975,1.03 6175 22368
278.3 Localized adiposity endocrine/metabolic Both 0.492 1.04 0.922,1.18 270 2694 0.5741 1.04 0.914,1.18 260 2592
278.4 Abnormal weight gain endocrine/metabolic Both 0.002679 1.08 1.03,1.14 1522 13685 0.004446 1.08 1.02,1.14 1457 13264
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.2992 1.02 0.98,1.07 2245 22393 0.3281 0.951 0.861,1.05 417 4306
279.1 Immunity deficiency endocrine/metabolic Both 0.3199 1.04 0.966,1.11 881 8792 0.6223 0.965 0.837,1.11 210 2461
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.857 0.988 0.868,1.13 254 2540 0.6223 0.965 0.837,1.11 210 2461
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.9311 0.996 0.914,1.09 574 5735 0.6745 0.981 0.899,1.07 539 5562
279.7 Other immunological findings endocrine/metabolic Both 0.004645 1.05 1.01,1.08 3927 30734 0.01143 1.05 1.01,1.08 3662 29800
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.4656 0.964 0.875,1.06 443 4423 0.3281 0.951 0.861,1.05 417 4306
275.1 Disorders of iron metabolism hematopoietic Both 0.01256 1.22 1.04,1.42 168 1680 0.006998 1.4 1.1,1.79 67 681
275.11 Hereditary hemochromatosis hematopoietic Both 0.01592 1.34 1.06,1.7 70 700 0.006998 1.4 1.1,1.79 67 681
280 Iron deficiency anemias hematopoietic Both 0.7586 1.01 0.971,1.04 3537 25593 0.6871 0.988 0.933,1.05 1269 13101
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.7745 1.01 0.97,1.04 3410 25349 0.9886 1.0 0.964,1.04 3203 24646
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.873 0.995 0.941,1.05 1361 13511 0.6871 0.988 0.933,1.05 1269 13101
281 Other deficiency anemia hematopoietic Both 0.6252 1.03 0.924,1.14 387 3838 0.5047 1.05 0.907,1.22 194 2027
281.1 Megaloblastic anemia hematopoietic Both 0.6683 0.968 0.833,1.12 189 1875 0.537 1.06 0.884,1.27 127 1308
281.11 Pernicious anemia hematopoietic Both 0.9886 1.0 0.801,1.25 84 830 0.9528 0.993 0.786,1.25 77 801
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.4732 1.07 0.895,1.27 135 1348 0.537 1.06 0.884,1.27 127 1308
281.9 Deficiency anemias hematopoietic Both 0.3097 1.08 0.934,1.24 214 2110 0.5047 1.05 0.907,1.22 194 2027
282 Hereditary hemolytic anemias hematopoietic Both 0.03565 1.15 1.01,1.32 248 2443 0.09268 1.16 0.975,1.39 135 1379
282.8 Other hemoglobinopathies hematopoietic Both 0.1611 1.12 0.954,1.32 158 1541 0.113 1.15 0.968,1.35 150 1490
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.1208 1.15 0.965,1.36 143 1420 0.09268 1.16 0.975,1.39 135 1379
283 Acquired hemolytic anemias hematopoietic Both 0.7638 1.03 0.86,1.23 130 1295 0.4236 1.08 0.894,1.31 113 1246
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.3076 1.16 0.873,1.54 54 532 ,
284 Aplastic anemia hematopoietic Both 0.6486 1.02 0.936,1.11 558 5545 0.5408 1.03 0.931,1.15 384 4699
284.1 Pancytopenia hematopoietic Both 0.6053 1.02 0.934,1.12 488 4847 0.5408 1.03 0.931,1.15 384 4699
285 Other anemias hematopoietic Both 0.778 1.0 0.98,1.03 9426 28014 0.3597 1.05 0.949,1.15 431 5361
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.811 0.995 0.955,1.04 2536 22457 0.7943 0.994 0.953,1.04 2403 21804
285.2 Anemia of chronic disease hematopoietic Both 0.2812 1.03 0.977,1.08 1584 15823 0.3597 1.05 0.949,1.15 431 5361
285.21 Anemia in chronic kidney disease hematopoietic Both 1.0 1.0 0.924,1.08 673 6722 0.8872 1.01 0.928,1.09 639 6503
285.22 Anemia in neoplastic disease hematopoietic Both 0.1112 1.07 0.984,1.17 555 5536 0.3597 1.05 0.949,1.15 431 5361
286 Coagulation defects hematopoietic Both 0.3357 0.982 0.945,1.02 3013 27144 0.787 0.99 0.921,1.06 816 8503
286.1 Congenital coagulation defects hematopoietic Both 0.9661 0.997 0.861,1.15 190 1889 0.2455 1.13 0.918,1.4 92 945
286.11 Von willebrand's disease hematopoietic Both 0.4093 0.9 0.699,1.16 64 640 0.2825 0.868 0.67,1.12 61 616
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.3076 1.11 0.907,1.36 98 973 0.2455 1.13 0.918,1.4 92 945
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.2042 0.974 0.935,1.01 2601 20964 0.1521 0.97 0.929,1.01 2426 20284
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.9705 1.0 0.776,1.3 60 590 0.9795 0.997 0.767,1.3 58 585
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.4178 0.941 0.812,1.09 186 1860 0.3319 0.927 0.797,1.08 174 1806
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.06871 0.826 0.672,1.01 92 906 0.03177 0.793 0.642,0.98 88 879
286.6 Defibrination syndrome hematopoietic Both 0.09099 0.961 0.917,1.01 1964 19522 0.05188 0.954 0.909,1.0 1839 18939
286.7 Other and unspecified coagulation defects hematopoietic Both 0.104 0.965 0.925,1.01 2349 23153 0.05408 0.958 0.917,1.0 2193 22467
286.8 Hypercoagulable state hematopoietic Both 0.6166 0.98 0.904,1.06 643 6420 0.4027 0.965 0.887,1.05 585 5999
286.81 Primary hypercoagulable state hematopoietic Both 0.5408 0.975 0.898,1.06 618 6179 0.4027 0.965 0.887,1.05 585 5999
286.9 Abnormal coagulation profile hematopoietic Both 0.9484 1.0 0.935,1.07 890 8770 0.787 0.99 0.921,1.06 816 8503
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.4305 0.984 0.944,1.02 2575 22699 0.1019 0.817 0.642,1.04 71 738
287.1 Spontaneous ecchymoses hematopoietic Both 0.3112 1.09 0.923,1.29 154 1532 0.3758 1.08 0.911,1.28 144 1486
287.3 Thrombocytopenia hematopoietic Both 0.354 0.98 0.938,1.02 2297 20909 0.07816 0.91 0.82,1.01 376 4227
287.31 Primary thrombocytopenia hematopoietic Both 0.7047 0.982 0.895,1.08 481 4785 0.5236 0.969 0.878,1.07 433 4638
287.32 Secondary thrombocytopenia hematopoietic Both 0.1279 0.927 0.841,1.02 436 4360 0.07816 0.91 0.82,1.01 376 4227
287.4 Qualitative platelet defects hematopoietic Both 0.04365 0.784 0.619,0.993 76 760 0.1019 0.817 0.642,1.04 71 738
288 Diseases of white blood cells hematopoietic Both 0.2667 1.02 0.986,1.05 3850 30383 0.9016 1.01 0.84,1.22 119 1264
288.1 Decreased white blood cell count hematopoietic Both 0.6653 0.987 0.932,1.05 1252 12520 0.631 0.982 0.91,1.06 725 8774
288.11 Neutropenia hematopoietic Both 0.6427 0.984 0.918,1.05 896 8960 0.631 0.982 0.91,1.06 725 8774
288.2 Elevated white blood cell count hematopoietic Both 0.1581 1.03 0.99,1.07 3179 28632 0.4365 1.02 0.977,1.05 2920 28109
288.3 Eosinophilia hematopoietic Both 0.5058 1.06 0.887,1.27 128 1278 0.9016 1.01 0.84,1.22 119 1264
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.7586 1.01 0.952,1.07 1259 12554 0.6714 1.03 0.905,1.17 263 2719
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.8356 1.01 0.928,1.1 615 6123 0.8872 1.01 0.923,1.1 578 6018
289.4 Lymphadenitis hematopoietic Both 0.02099 1.04 1.01,1.08 3186 28420 0.04508 1.04 1.0,1.08 2654 27903
289.5 Diseases of spleen hematopoietic Both 0.3076 0.942 0.84,1.06 313 3130 0.1542 0.914 0.807,1.03 269 3067
289.8 Polycythemia, secondary hematopoietic Both 0.9528 1.0 0.864,1.17 182 1820 0.8511 1.02 0.869,1.19 172 1788
289.9 Abnormality of red blood cells hematopoietic Both 0.7047 1.02 0.905,1.16 281 2776 0.6714 1.03 0.905,1.17 263 2719
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.2228 0.961 0.902,1.02 1040 9399 0.861 0.993 0.914,1.08 618 6125
290.1 Dementias mental disorders Both 0.2075 0.937 0.847,1.04 407 3816 0.2143 0.837 0.632,1.11 53 489
290.11 Alzheimer's disease mental disorders Both 0.2606 0.892 0.731,1.09 104 984 0.3639 0.91 0.744,1.11 98 930
290.12 Dementia with cerebral degenerations mental disorders Both 0.9977 1.0 0.791,1.27 71 705 0.9419 1.01 0.794,1.28 68 667
290.13 Senile dementia mental disorders Both 0.9931 0.999 0.881,1.13 257 2376 0.9572 0.997 0.876,1.13 245 2255
290.16 Vascular dementia mental disorders Both 0.1977 0.831 0.627,1.1 53 508 0.2143 0.837 0.632,1.11 53 489
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.5848 0.978 0.902,1.06 634 6242 0.5309 0.973 0.894,1.06 579 5984
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.8551 0.992 0.915,1.08 642 6369 0.861 0.993 0.914,1.08 618 6125
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.06516 1.04 0.997,1.09 1977 19673 0.1445 1.04 0.986,1.1 1470 14976
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.1016 0.872 0.741,1.03 161 1610 0.1012 0.871 0.739,1.03 159 1591
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.1959 1.07 0.964,1.2 364 3634 0.175 1.08 0.967,1.21 346 3520
291.8 Alteration of consciousness mental disorders Both 0.06871 1.05 0.996,1.11 1563 15497 0.1445 1.04 0.986,1.1 1470 14976
292 Neurological disorders mental disorders Both 0.6653 1.01 0.975,1.04 4340 31695 0.2818 0.909 0.765,1.08 134 1381
292.1 Aphasia/speech disturbance mental disorders Both 0.4027 0.978 0.929,1.03 1554 15459 0.1469 0.885 0.751,1.04 155 1555
292.11 Aphasia mental disorders Both 0.5495 0.973 0.89,1.06 516 5142 0.4977 0.969 0.883,1.06 485 4943
292.12 Symbolic dysfunction mental disorders Both 0.1535 0.889 0.757,1.04 162 1620 0.1469 0.885 0.751,1.04 155 1555
292.2 Mild cognitive impairment mental disorders Both 0.5943 0.967 0.856,1.09 276 2716 0.5649 0.964 0.85,1.09 261 2597
292.3 Memory loss mental disorders Both 0.3105 1.03 0.974,1.09 1405 13752 0.3758 1.03 0.97,1.09 1327 13267
292.4 Altered mental status mental disorders Both 0.6668 1.01 0.964,1.06 1885 18096 0.7745 1.01 0.959,1.06 1731 17431
292.5 Transient alteration of awareness mental disorders Both 0.4018 1.05 0.937,1.17 327 3237 0.5916 1.03 0.919,1.16 310 3121
292.6 Hallucinations mental disorders Both 0.3508 0.923 0.781,1.09 144 1429 0.2818 0.909 0.765,1.08 134 1381
293 Symptoms involving head and neck mental disorders Both 0.7745 1.02 0.905,1.14 304 3036 0.5728 1.01 0.975,1.05 3315 31535
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.2553 1.02 0.986,1.06 3691 32427 0.5728 1.01 0.975,1.05 3315 31535
295 Schizophrenia and other psychotic disorders mental disorders Both 0.5188 1.03 0.948,1.11 664 6564 0.7621 0.986 0.899,1.08 492 5006
295.1 Schizophrenia mental disorders Both 0.3027 1.11 0.91,1.35 111 1080 0.4256 1.09 0.887,1.33 106 1037
295.2 Paranoid disorders mental disorders Both 0.03981 1.25 1.01,1.54 86 856 0.138 1.18 0.947,1.48 76 825
295.3 Psychosis mental disorders Both 0.7798 0.987 0.904,1.08 527 5206 0.7621 0.986 0.899,1.08 492 5006
296 Mood disorders mental disorders Both 0.4266 1.01 0.986,1.03 12028 17942 0.4055 1.01 0.986,1.04 10368 17421
296.1 Bipolar mental disorders Both 0.1521 1.05 0.983,1.12 994 9331 0.2023 1.04 0.977,1.11 965 9090
296.2 Depression mental disorders Both 0.4797 1.01 0.985,1.03 11641 17941 0.4055 1.01 0.986,1.04 10368 17421
296.22 Major depressive disorder mental disorders Both 0.4315 1.01 0.986,1.03 10773 17942 0.4055 1.01 0.986,1.04 10368 17421
297 Suicidal ideation or attempt mental disorders Both 0.09397 0.936 0.866,1.01 696 6932 7.096E-4 0.774 0.668,0.898 196 1973
297.1 Suicidal ideation mental disorders Both 0.07278 0.924 0.847,1.01 559 5575 0.05943 0.919 0.841,1.0 536 5451
297.2 Suicide or self-inflicted injury mental disorders Both 0.001803 0.793 0.685,0.917 201 2010 7.096E-4 0.774 0.668,0.898 196 1973
300 Anxiety disorders mental disorders Both 0.2547 1.01 0.99,1.04 12038 17949 0.335 1.04 0.959,1.13 601 5963
300.1 Anxiety disorder mental disorders Both 0.1455 1.02 0.994,1.04 11352 17942 0.02404 1.09 1.01,1.18 696 7028
300.11 Generalized anxiety disorder mental disorders Both 0.1888 1.02 0.989,1.06 4496 17788 0.1242 1.03 0.993,1.06 4296 17266
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.1146 1.05 0.987,1.13 957 9152 0.08851 1.06 0.991,1.13 922 8910
300.13 Phobia mental disorders Both 0.02455 1.09 1.01,1.18 731 7231 0.02404 1.09 1.01,1.18 696 7028
300.3 Obsessive-compulsive disorders mental disorders Both 0.7362 0.977 0.854,1.12 223 2230 0.7464 0.977 0.851,1.12 212 2160
300.4 Dysthymic disorder mental disorders Both 0.1574 1.04 0.987,1.09 1798 13630 0.1216 1.04 0.99,1.09 1707 13239
300.8 Acute reaction to stress mental disorders Both 0.5272 1.04 0.929,1.15 359 3536 0.4266 1.05 0.937,1.17 347 3423
300.9 Posttraumatic stress disorder mental disorders Both 0.3656 1.04 0.957,1.13 612 6113 0.335 1.04 0.959,1.13 601 5963
301 Personality disorders mental disorders Both 0.863 0.991 0.89,1.1 363 3626 0.2523 0.916 0.787,1.06 182 1832
301.2 Antisocial/borderline personality disorder mental disorders Both 0.2944 0.923 0.795,1.07 187 1868 0.2523 0.916 0.787,1.06 182 1832
302 Sexual and gender identity disorders mental disorders Both 0.526 1.03 0.945,1.12 608 6055 0.6166 1.03 0.918,1.16 307 3142
302.1 Decreased libido mental disorders Both 0.6053 1.03 0.921,1.15 325 3233 0.6166 1.03 0.918,1.16 307 3142
303 Psychogenic and somatoform disorders mental disorders Both 0.8035 1.01 0.946,1.07 1030 10064 0.9908 1.0 0.934,1.07 895 8870
303.1 Dissociative disorder mental disorders Both 0.6871 0.963 0.803,1.16 115 1144 0.6966 0.964 0.804,1.16 114 1109
303.3 Psychogenic disorder mental disorders Both 0.6823 1.02 0.942,1.1 736 7330 0.4256 1.05 0.935,1.17 328 3276
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.4498 1.04 0.934,1.17 340 3376 0.4256 1.05 0.935,1.17 328 3276
303.4 Somatoform disorder mental disorders Both 0.9886 1.0 0.935,1.07 925 9106 0.9908 1.0 0.934,1.07 895 8870
304 Adjustment reaction mental disorders Both 0.8204 1.0 0.966,1.05 2840 17464 0.7889 1.01 0.966,1.05 2699 16946
305.2 Eating disorder mental disorders Both 0.3784 1.04 0.957,1.12 650 6500 0.4178 1.03 0.953,1.12 627 6348
306 Other mental disorder mental disorders Both 0.01807 1.07 1.01,1.14 1254 10907 0.6792 1.02 0.93,1.12 502 5079
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.877 1.01 0.911,1.12 418 2847 0.861 1.01 0.911,1.12 414 2801
306.9 Tension headache mental disorders Both 0.8017 1.01 0.925,1.11 521 5210 0.6792 1.02 0.93,1.12 502 5079
312 Conduct disorders mental disorders Both 0.4699 0.947 0.817,1.1 189 1890 0.1104 0.781 0.577,1.06 52 515
312.3 Impulse control disorder mental disorders Both 0.1694 0.811 0.601,1.09 53 530 0.1104 0.781 0.577,1.06 52 515
313 Pervasive developmental disorders mental disorders Both 0.3882 0.974 0.916,1.03 1148 11078 0.7244 1.05 0.804,1.37 58 573
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.5224 0.979 0.918,1.04 1012 9899 0.4966 0.978 0.916,1.04 987 9662
313.2 Tics and stuttering mental disorders Both 0.9638 1.01 0.775,1.31 60 593 0.7244 1.05 0.804,1.37 58 573
315 Develomental delays and disorders mental disorders Both 0.04943 0.903 0.815,1.0 401 3990 0.1552 0.894 0.767,1.04 171 1748
315.1 Learning disorder mental disorders Both 0.9931 1.0 0.772,1.3 60 599 0.6918 1.06 0.807,1.38 57 585
315.2 Speech and language disorder mental disorders Both 0.2153 0.91 0.784,1.06 182 1801 0.1552 0.894 0.767,1.04 171 1748
316 Substance addiction and disorders mental disorders Both 0.7709 1.01 0.967,1.05 2799 26014 0.1256 1.08 0.979,1.19 435 5033
316.1 Polyneuropathy due to drugs mental disorders Both 0.06622 1.09 0.994,1.19 518 5180 0.1256 1.08 0.979,1.19 435 5033
317 Alcohol-related disorders mental disorders Both 0.1253 0.964 0.92,1.01 1948 17547 0.2723 0.938 0.838,1.05 321 3235
317.1 Alcoholism mental disorders Both 0.1629 0.963 0.914,1.02 1517 14733 0.2723 0.938 0.838,1.05 321 3235
317.11 Alcoholic liver damage mental disorders Both 0.2148 0.932 0.834,1.04 335 3336 0.2723 0.938 0.838,1.05 321 3235
318 Tobacco use disorder mental disorders Both 0.514 0.992 0.969,1.02 9473 26924 0.5741 0.993 0.969,1.02 9043 26150
320 Meningitis neurological Both 0.4667 1.04 0.931,1.17 319 3181 0.342 1.06 0.941,1.19 297 3053
323 Encephalitis neurological Both 0.7962 0.978 0.827,1.16 148 1475 0.5741 0.948 0.788,1.14 119 1206
323.8 Encephalitis, non-infectious neurological Both 0.7096 0.966 0.807,1.16 125 1245 0.5741 0.948 0.788,1.14 119 1206
324 Other CNS infection and poliomyelitis neurological Both 0.6808 1.03 0.901,1.17 245 2440 0.5794 1.04 0.908,1.19 230 2333
327 Sleep disorders neurological Both 0.5943 1.01 0.984,1.03 11517 26652 0.5117 0.913 0.695,1.2 54 530
327.1 Hypersomnia neurological Both 0.6237 1.01 0.96,1.07 1403 13919 0.7834 1.01 0.953,1.07 1359 13452
327.3 Sleep apnea neurological Both 0.8035 1.0 0.978,1.03 8293 26193 0.8511 0.997 0.97,1.03 6302 24703
327.31 Central/nonobstroctive sleep apnea neurological Both 0.07345 1.11 0.99,1.24 326 3234 0.05741 1.12 0.997,1.26 313 3120
327.32 Obstructive sleep apnea neurological Both 0.826 0.997 0.97,1.02 6534 25537 0.8511 0.997 0.97,1.03 6302 24703
327.4 Insomnia neurological Both 0.05623 1.03 0.999,1.07 4197 25860 0.4842 1.03 0.955,1.1 840 8441
327.41 Organic or persistent insomnia neurological Both 0.4613 1.03 0.958,1.1 881 8743 0.4842 1.03 0.955,1.1 840 8441
327.5 Parasomnia neurological Both 0.8872 1.01 0.914,1.11 459 4583 0.826 1.01 0.915,1.12 437 4409
327.6 Circadian rhythm sleep disorder neurological Both 0.6339 0.964 0.828,1.12 174 1738 0.5164 0.95 0.815,1.11 170 1677
327.7 Sleep related movement disorders neurological Both 0.3177 1.03 0.973,1.09 1364 13620 0.5117 0.913 0.695,1.2 54 530
327.71 Restless legs syndrome neurological Both 0.415 1.02 0.966,1.09 1214 12132 0.5047 1.02 0.961,1.08 1175 11694
327.72 Sleep related leg cramps neurological Both 0.5768 0.926 0.705,1.21 55 550 0.5117 0.913 0.695,1.2 54 530
331 Other cerebral degenerations neurological Both 0.2018 1.06 0.971,1.15 602 5935 0.4519 1.05 0.932,1.17 317 3264
331.1 Hydrocephalus neurological Both 0.195 1.09 0.957,1.24 246 2447 0.1574 1.1 0.964,1.25 238 2349
331.9 Cerebral degeneration, unspecified neurological Both 0.4864 1.04 0.932,1.16 349 3423 0.4519 1.05 0.932,1.17 317 3264
332 Parkinson's disease neurological Both 0.2685 0.939 0.839,1.05 333 3321 0.3373 0.945 0.843,1.06 321 3161
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.5129 0.985 0.943,1.03 2169 20920 0.4457 1.11 0.853,1.44 63 614
333.1 Essential tremor neurological Both 0.3972 0.963 0.884,1.05 551 5488 0.3882 0.962 0.881,1.05 528 5267
333.2 Myoclonus neurological Both 0.2786 0.899 0.742,1.09 117 1160 0.2158 0.882 0.724,1.08 109 1130
333.4 Torsion dystonia neurological Both 0.09977 0.899 0.791,1.02 266 2646 0.04797 0.877 0.77,0.999 255 2554
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.3319 1.14 0.877,1.47 64 640 0.4457 1.11 0.853,1.44 63 614
334 Degenerative disease of the spinal cord neurological Both 0.1774 1.05 0.979,1.12 874 8734 0.912 0.985 0.751,1.29 54 542
334.1 Spinocerebellar disease neurological Both 0.3681 1.12 0.871,1.45 64 631 0.3873 1.12 0.862,1.47 58 612
334.2 Anterior horn cell disease neurological Both 0.618 1.05 0.855,1.3 92 920 0.912 0.985 0.751,1.29 54 542
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.7499 0.958 0.738,1.24 57 570 0.912 0.985 0.751,1.29 54 542
335 Multiple sclerosis neurological Both 0.8531 1.01 0.902,1.13 330 3284 0.9376 1.0 0.895,1.13 323 3169
337 Disorders of the autonomic nervous system neurological Both 0.9099 0.995 0.911,1.09 528 5257 0.2938 0.917 0.78,1.08 170 1771
337.1 Peripheral autonomic neuropathy neurological Both 0.1726 0.898 0.768,1.05 185 1837 0.2938 0.917 0.78,1.08 170 1771
338 Pain neurological Both 0.3631 1.01 0.989,1.03 16189 22165 0.1786 1.02 0.992,1.04 7882 21513
338.1 Acute pain neurological Both 0.5572 1.01 0.985,1.03 12567 22166 0.8375 1.0 0.98,1.02 12030 21525
338.2 Chronic pain neurological Both 0.1416 1.02 0.994,1.05 8223 22154 0.1786 1.02 0.992,1.04 7882 21513
339 Other headache syndromes neurological Both 0.04909 1.03 1.0,1.05 8578 27793 0.06053 1.02 0.999,1.05 8227 26899
340 Migraine neurological Both 0.03741 1.03 1.0,1.06 5377 24263 0.07079 1.04 0.997,1.08 2774 18094
340.1 Migrain with aura neurological Both 0.03908 1.04 1.0,1.08 2862 18665 0.07079 1.04 0.997,1.08 2774 18094
341 Other demyelinating diseases of central nervous system neurological Both 0.6637 0.958 0.79,1.16 111 1105 0.5754 0.946 0.778,1.15 108 1074
342 Hemiplegia neurological Both 0.3715 1.05 0.944,1.17 360 3589 0.4688 1.04 0.933,1.16 341 3465
343 Infantile cerebral palsy neurological Both 0.3491 0.893 0.705,1.13 75 750 0.3548 0.894 0.704,1.13 75 728
344 Other paralytic syndromes neurological Both 0.2056 1.06 0.97,1.15 564 5640 0.2818 1.05 0.961,1.15 539 5448
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.869 1.0 0.96,1.05 2084 20790 0.8913 0.997 0.951,1.05 1878 19019
345.1 Epilepsy neurological Both 0.3828 1.04 0.955,1.13 607 6053 0.811 1.01 0.916,1.12 408 4207
345.11 Generalized convulsive epilepsy neurological Both 0.526 0.954 0.823,1.1 196 1960 0.25 0.915 0.787,1.06 186 1903
345.12 Partial epilepsy neurological Both 0.5117 1.03 0.937,1.14 434 4333 0.811 1.01 0.916,1.12 408 4207
345.3 Convulsions neurological Both 0.8492 0.996 0.95,1.04 1967 19598 0.8913 0.997 0.951,1.05 1878 19019
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.7161 1.03 0.87,1.22 142 1404 0.2559 1.15 0.903,1.47 67 858
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.3917 0.975 0.919,1.03 1196 11927 0.3565 0.972 0.914,1.03 1106 11511
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.1074 1.2 0.962,1.49 87 860 0.05176 1.25 0.998,1.56 80 832
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.7852 1.03 0.834,1.27 90 884 0.2559 1.15 0.903,1.47 67 858
347 Cataplexy and narcolepsy neurological Both 0.8872 1.02 0.803,1.29 67 670 0.7943 1.03 0.814,1.31 66 658
348 Other conditions of brain neurological Both 0.5808 1.02 0.961,1.07 1424 14226 0.4159 1.02 0.972,1.07 1871 19315
348.2 Cerebral edema and compression of brain neurological Both 0.6546 1.02 0.943,1.1 747 7463 0.6442 1.02 0.941,1.1 685 7217
348.4 Cerebral cysts neurological Both 0.798 0.98 0.844,1.14 195 1945 0.9572 0.996 0.855,1.16 188 1893
348.7 Coma neurological Both 0.5728 0.954 0.811,1.12 162 1620 0.7396 0.972 0.823,1.15 155 1572
348.8 Encephalopathy, not elsewhere classified neurological Both 0.542 1.03 0.946,1.11 636 6331 0.5689 1.02 0.943,1.11 585 6070
348.9 Other conditions of brain, NOS neurological Both 0.3963 1.02 0.974,1.07 2001 19979 0.4159 1.02 0.972,1.07 1871 19315
349 Other and unspecified disorders of the nervous system neurological Both 0.455 1.03 0.955,1.11 775 7750 0.6855 1.02 0.941,1.1 731 7471
350 Abnormal movement neurological Both 0.857 0.997 0.968,1.03 5109 32314 0.3516 1.05 0.948,1.16 413 4314
350.1 Abnormal involuntary movements neurological Both 0.5383 1.01 0.972,1.06 2464 24243 0.4295 1.02 0.975,1.06 2325 23412
350.2 Abnormality of gait neurological Both 0.6194 1.01 0.972,1.05 2979 25007 0.8091 1.0 0.966,1.04 2831 24135
350.3 Lack of coordination neurological Both 0.3741 0.967 0.898,1.04 773 7693 0.4055 0.968 0.897,1.04 726 7418
350.5 Abnormal reflex neurological Both 0.631 1.04 0.878,1.24 143 1430 0.7178 1.03 0.865,1.23 134 1380
350.6 Disturbances of sensation of smell and taste neurological Both 0.369 1.05 0.949,1.15 448 4480 0.3516 1.05 0.948,1.16 413 4314
351 Other peripheral nerve disorders neurological Both 0.07852 1.03 0.997,1.06 5685 28844 0.1807 1.02 0.991,1.05 5391 27953
352 Disorders of other cranial nerves neurological Both 0.02871 1.06 1.01,1.12 1412 14120 0.4325 1.03 0.951,1.12 601 6188
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.005188 1.15 1.04,1.27 440 4393 0.009162 1.14 1.03,1.27 418 4237
352.2 Facial nerve disorders [CN7] neurological Both 0.399 1.04 0.955,1.12 640 6400 0.4325 1.03 0.951,1.12 601 6188
353 Nerve root and plexus disorders neurological Both 0.04786 1.04 1.0,1.08 3295 28097 0.4198 1.09 0.88,1.36 87 909
353.1 Nerve plexus lesions neurological Both 0.542 0.965 0.861,1.08 308 3077 0.4966 0.96 0.854,1.08 290 2982
353.2 Nerve root lesions neurological Both 0.5649 1.06 0.863,1.31 94 930 0.4198 1.09 0.88,1.36 87 909
355 Complex regional/central pain syndrome neurological Both 0.1426 1.08 0.975,1.19 419 4170 0.6486 1.02 0.939,1.11 630 6309
355.1 Chronic pain syndrome neurological Both 0.5623 1.02 0.945,1.11 654 6509 0.6486 1.02 0.939,1.11 630 6309
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.2576 0.972 0.925,1.02 1728 17176 0.2188 0.968 0.919,1.02 1600 16521
357 Inflammatory and toxic neuropathy neurological Both 0.9162 0.998 0.957,1.04 2467 24091 0.8147 0.995 0.953,1.04 2276 23229
358 Myoneural disorders neurological Both 0.4395 1.03 0.959,1.1 845 8441 0.3381 0.901 0.728,1.12 82 818
358.1 Myasthenia gravis neurological Both 0.2951 0.893 0.723,1.1 85 850 0.3381 0.901 0.728,1.12 82 818
359 Muscular dystrophies and other myopathies neurological Both 0.955 1.0 0.934,1.07 868 8655 0.7621 0.989 0.919,1.06 793 8016
359.1 Muscular dystrophies neurological Both 0.7129 0.946 0.705,1.27 52 520 ,
359.2 Myopathy neurological Both 0.7586 0.989 0.921,1.06 833 8306 0.7621 0.989 0.919,1.06 793 8016
360 Disorders of the globe sense organs Both 0.9705 1.0 0.823,1.22 102 1013 0.7568 1.03 0.844,1.26 99 974
361 Retinal detachments and defects sense organs Both 0.2312 0.947 0.867,1.04 528 5265 0.6095 1.04 0.9,1.2 211 2125
361.1 Retinal detachment with retinal defect sense organs Both 0.8414 1.01 0.884,1.16 225 2226 0.6095 1.04 0.9,1.2 211 2125
362 Other retinal disorders sense organs Both 0.7396 1.01 0.966,1.05 2489 18838 0.875 1.01 0.873,1.17 187 1911
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.7311 0.991 0.94,1.04 1529 12328 0.9908 1.0 0.943,1.06 1235 10464
362.21 Macular degeneration, dry sense organs Both 0.8299 1.01 0.904,1.13 313 2650 0.8054 1.02 0.901,1.14 286 2527
362.22 Macular degeneration, wet sense organs Both 0.4276 1.08 0.895,1.3 108 881 0.8222 1.02 0.84,1.24 98 837
362.23 Cystoid macular degeneration of retina sense organs Both 0.3148 0.94 0.833,1.06 285 2777 0.4753 0.956 0.844,1.08 270 2673
362.26 Macular puckering of retina sense organs Both 0.5559 1.02 0.946,1.11 645 6254 0.5433 1.03 0.945,1.11 608 5995
362.27 Drusen (degenerative) of retina sense organs Both 0.865 0.991 0.887,1.11 335 3205 0.873 0.991 0.884,1.11 311 3072
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.877 0.996 0.941,1.05 1323 10928 0.9908 1.0 0.943,1.06 1235 10464
362.3 Other nondiabetic retinopathy sense organs Both 0.1694 1.06 0.976,1.15 653 6476 0.9705 0.998 0.883,1.13 275 2813
362.31 Separation of retinal layers sense organs Both 0.8185 0.986 0.877,1.11 296 2938 0.9705 0.998 0.883,1.13 275 2813
362.4 Retinal vascular changes and abnomalities sense organs Both 0.6918 1.02 0.927,1.12 449 4295 0.8933 1.01 0.912,1.11 418 4119
362.6 Peripheral retinal degenerations sense organs Both 0.6095 1.03 0.912,1.17 262 2600 0.4375 1.05 0.926,1.2 253 2510
362.7 Hereditary retinal dystrophies sense organs Both 0.4498 1.07 0.894,1.29 124 1233 0.3214 1.1 0.912,1.33 116 1186
362.8 Retinal hemorrhage/ischemia sense organs Both 0.6683 0.966 0.822,1.13 160 1570 0.2877 0.912 0.77,1.08 144 1511
362.9 Retinal edema sense organs Both 0.7834 1.02 0.885,1.18 202 2001 0.875 1.01 0.873,1.17 187 1911
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.3793 0.954 0.86,1.06 375 3665 0.2911 0.931 0.814,1.06 234 2336
363.3 Chorioretinal scars sense organs Both 0.414 0.948 0.833,1.08 249 2430 0.2911 0.931 0.814,1.06 234 2336
364 Corneal opacity and other disorders of cornea sense organs Both 0.1521 1.05 0.981,1.13 809 7919 0.3698 1.12 0.872,1.44 66 653
364.1 Corneal opacity sense organs Both 0.9162 0.994 0.883,1.12 294 2930 0.7499 1.02 0.903,1.15 282 2808
364.2 Corneal edema sense organs Both 0.4121 1.1 0.881,1.36 84 819 0.3516 1.11 0.891,1.38 83 786
364.4 Corneal degenerations sense organs Both 0.2084 1.08 0.957,1.22 274 2719 0.1959 1.09 0.958,1.23 260 2616
364.5 Corneal dystrophy sense organs Both 0.2133 1.07 0.962,1.19 377 3673 0.4256 1.06 0.917,1.23 198 1937
364.51 Fuchs' dystrophy sense organs Both 0.3192 1.08 0.932,1.24 207 2008 0.4256 1.06 0.917,1.23 198 1937
364.9 Cornea replaced by transplant sense organs Both 0.4009 1.11 0.869,1.42 69 677 0.3698 1.12 0.872,1.44 66 653
365 Glaucoma sense organs Both 0.4036 1.02 0.974,1.07 1986 17152 0.9616 1.0 0.854,1.18 172 1625
365.1 Open-angle glaucoma sense organs Both 0.2178 1.06 0.968,1.16 523 4963 0.1486 1.1 0.967,1.25 256 2497
365.11 Primary open angle glaucoma sense organs Both 0.1683 1.09 0.965,1.23 281 2609 0.1486 1.1 0.967,1.25 256 2497
365.2 Primary angle-closure glaucoma sense organs Both 0.9268 1.01 0.86,1.18 179 1707 0.9616 1.0 0.854,1.18 172 1625
366 Cataract sense organs Both 0.2193 1.02 0.989,1.05 6335 23476 0.4285 1.01 0.979,1.05 3611 19645
366.1 Nonsenile Cataract sense organs Both 0.778 1.02 0.868,1.21 163 1622 0.8017 1.02 0.862,1.21 156 1551
366.2 Senile cataract sense organs Both 0.389 1.02 0.98,1.05 3827 20410 0.4285 1.01 0.979,1.05 3611 19645
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.354 1.01 0.986,1.04 6553 31745 0.2244 1.04 0.975,1.12 930 9305
367.1 Myopia sense organs Both 0.4764 1.01 0.978,1.05 3578 28818 0.4797 1.01 0.978,1.05 3438 27896
367.2 Astigmatism sense organs Both 0.4819 1.01 0.976,1.05 2892 26106 0.4169 1.02 0.977,1.06 2777 25227
367.4 Presbyopia sense organs Both 0.4009 1.02 0.979,1.05 3297 24582 0.537 1.01 0.975,1.05 3137 23669
367.8 Hypermetropia sense organs Both 0.2239 0.968 0.917,1.02 1504 14729 0.173 0.963 0.912,1.02 1439 14153
367.9 Blindness and low vision sense organs Both 0.2037 1.04 0.977,1.11 976 9663 0.2244 1.04 0.975,1.12 930 9305
368 Visual disturbances sense organs Both 0.156 1.02 0.991,1.06 4287 32818 0.8892 1.02 0.818,1.26 83 844
368.1 Amblyopia sense organs Both 0.5808 0.974 0.888,1.07 484 4830 0.5559 0.972 0.884,1.07 466 4665
368.2 Diplopia and disorders of binocular vision sense organs Both 0.2679 1.04 0.969,1.12 822 8186 0.1914 1.05 0.976,1.13 775 7862
368.3 Anisometropia sense organs Both 0.3784 0.93 0.791,1.09 166 1648 0.3141 0.919 0.779,1.08 160 1597
368.4 Visual field defects sense organs Both 0.02685 1.08 1.01,1.16 879 8777 0.02301 1.08 1.01,1.16 843 8439
368.9 Subjective visual disturbances sense organs Both 0.3184 0.964 0.898,1.04 829 8268 0.8892 1.02 0.818,1.26 83 844
368.91 Psychophysical visual disturbances sense organs Both 0.7096 1.04 0.843,1.29 89 885 0.8892 1.02 0.818,1.26 83 844
369 Infection of the eye sense organs Both 0.1327 1.03 0.99,1.08 2328 22262 0.05585 1.05 0.999,1.1 1891 18806
369.2 Eye infection, viral sense organs Both 0.9183 1.01 0.903,1.12 372 3688 0.7244 1.02 0.913,1.14 354 3561
369.5 Conjunctivitis, infectious sense organs Both 0.0873 1.04 0.994,1.09 1974 19408 0.05585 1.05 0.999,1.1 1891 18806
370 Keratitis sense organs Both 0.526 1.02 0.958,1.09 1051 10280 0.7834 0.976 0.819,1.16 139 1371
370.1 Corneal ulcer sense organs Both 0.2924 1.09 0.931,1.27 164 1630 0.3097 1.08 0.928,1.27 163 1596
370.2 Superficial keratitis sense organs Both 0.1837 1.07 0.967,1.19 394 3916 0.07499 1.1 0.99,1.22 376 3776
370.3 Keratoconjunctivitis sense organs Both 0.6266 0.978 0.892,1.07 531 5159 0.7834 0.976 0.819,1.16 139 1371
370.31 Keratoconjunctivitis sicca sense organs Both 0.8531 1.02 0.859,1.2 150 1432 0.7834 0.976 0.819,1.16 139 1371
371 Inflammation of the eye sense organs Both 0.06194 1.04 0.998,1.07 3269 26161 0.4887 0.929 0.753,1.15 97 945
371.1 Uveitis, noninfectious or NOS sense organs Both 0.778 0.985 0.889,1.09 394 3892 0.873 0.991 0.892,1.1 372 3760
371.2 Conjunctivitis, noninfectious sense organs Both 0.3289 1.04 0.96,1.13 651 6462 0.2265 1.06 0.965,1.16 505 5099
371.21 Allergic conjunctivitis sense organs Both 0.1321 1.07 0.979,1.17 532 5279 0.2265 1.06 0.965,1.16 505 5099
371.3 Inflammation of eyelids sense organs Both 0.1675 1.03 0.988,1.07 2523 21781 0.4887 0.929 0.753,1.15 97 945
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.6653 0.956 0.778,1.17 100 979 0.4887 0.929 0.753,1.15 97 945
372 Disorders of conjunctiva sense organs Both 0.7413 0.988 0.921,1.06 827 8153 0.955 0.998 0.928,1.07 782 7840
374 Other disorders of eyelids sense organs Both 0.1081 1.04 0.992,1.09 2093 18512 0.002366 1.13 1.04,1.22 716 7129
374.1 Ectropion or entropion sense organs Both 0.2999 1.06 0.95,1.18 337 3251 0.3733 1.05 0.939,1.18 311 3112
374.2 Lagophthalmos sense organs Both 0.514 0.952 0.821,1.1 192 1900 0.3597 0.931 0.8,1.08 181 1837
374.3 Ptosis of eyelid sense organs Both 0.07745 1.07 0.993,1.14 817 8140 0.03864 1.08 1.0,1.16 766 7824
374.6 Dermatochalasis sense organs Both 0.003327 1.12 1.04,1.2 759 7426 0.002366 1.13 1.04,1.22 716 7129
375 Disorders of lacrimal system sense organs Both 0.8492 0.996 0.957,1.04 2683 21054 0.3639 0.949 0.849,1.06 348 3424
375.1 Dry eyes sense organs Both 0.618 1.01 0.972,1.05 2966 21823 0.6281 1.01 0.971,1.05 2798 21062
375.2 Epiphora sense organs Both 0.3664 0.95 0.851,1.06 356 3540 0.3639 0.949 0.849,1.06 348 3424
376 Disorders of the orbit sense organs Both 0.7194 0.978 0.867,1.1 285 2814 0.7674 0.982 0.868,1.11 272 2729
377 Disorders of optic nerve and visual pathways sense organs Both 0.2884 1.04 0.965,1.13 706 7010 0.169 1.07 0.971,1.18 450 4470
377.1 Optic atrophy sense organs Both 0.3342 1.07 0.929,1.24 200 1997 0.2612 1.09 0.938,1.27 189 1925
377.3 Optic neuritis/neuropathy sense organs Both 0.08531 1.09 0.988,1.19 468 4627 0.169 1.07 0.971,1.18 450 4470
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.7816 1.01 0.945,1.08 969 9602 0.09594 1.12 0.981,1.27 253 2614
378.1 Strabismus (not specified as paralytic) sense organs Both 0.5117 0.973 0.895,1.06 617 6131 0.5649 0.975 0.896,1.06 591 5913
378.2 Nystagmus and other irregular eye movements sense organs Both 0.861 1.02 0.854,1.21 138 1371 0.9247 1.01 0.845,1.2 131 1319
378.5 Paralytic strabismus sense organs Both 0.1648 1.09 0.964,1.24 275 2720 0.09594 1.12 0.981,1.27 253 2614
379 Other disorders of eye sense organs Both 0.6792 1.01 0.972,1.04 3593 24835 0.7998 0.991 0.922,1.06 825 8317
379.1 Scleritis and episcleritis sense organs Both 0.2328 0.9 0.757,1.07 140 1379 0.1762 0.886 0.744,1.06 137 1335
379.2 Disorders of vitreous body sense organs Both 0.871 1.0 0.962,1.05 2559 18709 0.811 1.01 0.963,1.05 2400 17988
379.3 Aphakia and other disorders of lens sense organs Both 0.1837 1.16 0.931,1.45 87 838 0.1486 1.18 0.942,1.49 83 803
379.4 Anomalies of pupillary function sense organs Both 0.9057 0.992 0.866,1.14 231 2303 0.8831 1.01 0.878,1.16 218 2234
379.5 Disorders of iris and ciliary body sense organs Both 0.5433 1.05 0.906,1.21 215 2128 0.492 1.1 0.839,1.44 61 588
379.51 Pigmentary iris degeneration sense organs Both 0.4426 1.11 0.849,1.46 61 610 0.492 1.1 0.839,1.44 61 588
379.9 Pain, swelling or discharge of eye sense organs Both 0.9886 1.0 0.933,1.07 870 8594 0.7998 0.991 0.922,1.06 825 8317
380 Disorders of external ear sense organs Both 0.1259 1.04 0.989,1.09 1634 15553 0.5781 1.01 0.967,1.06 1878 17910
380.1 Otitis externa sense organs Both 0.04581 1.06 1.0,1.13 1124 11213 0.08241 1.06 0.993,1.13 1083 10803
380.4 Impacted cerumen sense organs Both 0.3304 1.02 0.977,1.07 1985 18630 0.5781 1.01 0.967,1.06 1878 17910
381 Otitis media and Eustachian tube disorders sense organs Both 0.1285 1.03 0.992,1.07 3291 29339 0.8851 1.01 0.894,1.14 284 2861
381.1 Otitis media sense organs Both 0.4467 1.02 0.975,1.06 2402 23549 0.369 1.02 0.975,1.07 1969 19575
381.11 Suppurative and unspecified otitis media sense organs Both 0.2799 1.03 0.98,1.07 2037 20175 0.369 1.02 0.975,1.07 1969 19575
381.2 Eustachian tube disorders sense organs Both 0.08204 1.05 0.994,1.11 1393 13815 0.1734 1.04 0.983,1.1 1337 13344
381.3 Mastoiditis & related conditions sense organs Both 0.7228 0.968 0.806,1.16 126 1260 0.5984 0.952 0.793,1.14 124 1229
381.9 Otorrhea sense organs Both 0.7379 1.02 0.907,1.15 297 2960 0.8851 1.01 0.894,1.14 284 2861
382 Otalgia sense organs Both 0.173 1.04 0.984,1.1 1425 14188 0.2339 1.03 0.978,1.09 1358 13715
383 Otosclerosis sense organs Both 0.811 0.976 0.802,1.19 112 1120 0.8872 0.986 0.809,1.2 111 1091
384 Other disorders of tympanic membrane sense organs Both 0.2576 0.943 0.851,1.04 397 3962 0.2051 0.927 0.824,1.04 302 3093
384.4 Perforation of tympanic membrane sense organs Both 0.3396 0.946 0.843,1.06 318 3180 0.2051 0.927 0.824,1.04 302 3093
385 Other disorders of middle ear and mastoid sense organs Both 0.8375 0.989 0.888,1.1 358 3580 0.1841 0.872 0.712,1.07 101 996
385.3 Cholesteatoma sense organs Both 0.6295 0.969 0.852,1.1 245 2450 0.618 0.967 0.849,1.1 238 2383
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.1493 0.863 0.707,1.05 103 1025 0.1841 0.872 0.712,1.07 101 996
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.156 1.04 0.985,1.1 1441 14255 0.002864 1.05 1.02,1.08 5043 30594
386.1 Meniere's disease sense organs Both 0.5358 1.04 0.917,1.18 248 2464 0.5433 1.04 0.915,1.18 240 2374
386.2 Peripheral or central vertigo sense organs Both 0.4592 1.02 0.964,1.08 1209 11971 0.3273 1.04 0.965,1.11 851 8437
386.21 Central origin vertigo sense organs Both 0.2168 1.04 0.975,1.12 883 8759 0.3273 1.04 0.965,1.11 851 8437
386.3 Labyrinthitis sense organs Both 0.05572 1.06 0.999,1.13 1099 10904 0.1337 1.05 0.985,1.12 1057 10510
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.001786 1.05 1.02,1.08 5315 31605 0.002864 1.05 1.02,1.08 5043 30594
388 Other disorders of ear sense organs Both 0.1972 0.95 0.879,1.03 699 6960 0.1633 0.945 0.874,1.02 670 6737
389 Hearing loss sense organs Both 0.5702 1.01 0.981,1.04 6285 31750 0.1552 0.861 0.7,1.06 98 975
389.1 Sensorineural hearing loss sense organs Both 0.4742 1.01 0.977,1.05 3130 24231 0.6823 1.01 0.97,1.05 2977 23357
389.2 Conductive hearing loss sense organs Both 0.7311 1.01 0.938,1.1 717 7169 0.6871 1.02 0.939,1.1 690 6953
389.3 Degenerative and vascular disorders of ear sense organs Both 0.5715 0.952 0.802,1.13 143 1338 0.7178 0.968 0.813,1.15 137 1281
389.4 Tinnitus sense organs Both 0.4634 0.981 0.933,1.03 1677 16701 0.4592 0.981 0.931,1.03 1593 16116
389.5 Disorders of acoustic nerve sense organs Both 0.1607 0.864 0.705,1.06 101 1010 0.1552 0.861 0.7,1.06 98 975
394 Rheumatic disease of the heart valves circulatory system Both 0.07447 0.947 0.892,1.01 1177 11253 0.5383 0.97 0.879,1.07 438 4473
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.5675 0.966 0.856,1.09 284 2766 0.3451 0.942 0.831,1.07 263 2652
394.2 Mitral valve disease circulatory system Both 0.1578 0.927 0.835,1.03 378 3735 0.139 0.922 0.828,1.03 360 3577
394.3 Aortic valve disease circulatory system Both 0.8318 0.982 0.834,1.16 150 1465 0.929 0.992 0.839,1.17 143 1383
394.7 Disease of tricuspid valve circulatory system Both 0.5689 0.973 0.885,1.07 468 4624 0.5383 0.97 0.879,1.07 438 4473
395 Heart valve disorders circulatory system Both 0.5284 0.988 0.952,1.03 3169 23926 0.7211 0.987 0.919,1.06 834 7887
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.2858 0.974 0.927,1.02 1754 16787 0.2642 0.972 0.924,1.02 1671 16171
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.8511 0.995 0.945,1.05 1619 13932 0.5875 0.986 0.935,1.04 1533 13373
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.5105 0.965 0.869,1.07 373 3704 0.7534 0.983 0.882,1.09 355 3565
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.4842 1.08 0.863,1.36 84 831 0.414 1.1 0.874,1.39 82 819
395.6 Heart valve replaced circulatory system Both 0.9016 0.996 0.929,1.07 878 8213 0.7211 0.987 0.919,1.06 834 7887
396 Abnormal heart sounds circulatory system Both 0.2173 0.979 0.946,1.01 3754 28453 0.2523 0.98 0.946,1.01 3585 27479
401 Hypertension circulatory system Both 0.09397 1.02 0.997,1.04 18784 19071 0.02992 1.06 1.01,1.11 1920 12521
401.1 Essential hypertension circulatory system Both 0.0861 1.02 0.997,1.04 18655 19070 0.09441 1.02 0.997,1.04 17894 18540
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.2037 1.03 0.984,1.08 2599 12045 0.3963 1.02 0.971,1.08 1897 10509
401.21 Hypertensive heart disease circulatory system Both 0.1637 1.06 0.975,1.16 556 4628 0.2679 1.05 0.961,1.15 522 4436
401.22 Hypertensive chronic kidney disease circulatory system Both 0.3622 1.02 0.974,1.08 2015 10909 0.3963 1.02 0.971,1.08 1897 10509
401.3 Other hypertensive complications circulatory system Both 0.01406 1.06 1.01,1.11 2027 12961 0.02992 1.06 1.01,1.11 1920 12521
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.02046 1.06 1.01,1.11 2132 15248 0.02183 1.06 1.01,1.11 2032 14758
411 Ischemic Heart Disease circulatory system Both 0.2009 0.982 0.955,1.01 6970 25468 0.3837 0.95 0.845,1.07 306 3112
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.3733 1.04 0.958,1.12 702 6842 0.4519 1.03 0.952,1.12 671 6586
411.2 Myocardial infarction circulatory system Both 0.3258 0.98 0.941,1.02 2849 17983 0.2312 0.975 0.936,1.02 2711 17335
411.3 Angina pectoris circulatory system Both 0.2553 0.973 0.927,1.02 1904 15218 0.2286 0.97 0.924,1.02 1820 14660
411.4 Coronary atherosclerosis circulatory system Both 0.2965 0.984 0.955,1.01 5938 22890 0.07145 1.19 0.985,1.43 114 1113
411.41 Aneurysm and dissection of heart circulatory system Both 0.06026 1.19 0.992,1.44 117 1149 0.07145 1.19 0.985,1.43 114 1113
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.1574 0.977 0.946,1.01 4877 21174 0.07745 0.97 0.939,1.0 4638 20436
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.4009 0.953 0.853,1.07 335 3247 0.3837 0.95 0.845,1.07 306 3112
414 Other forms of chronic heart disease circulatory system Both 0.3034 0.978 0.937,1.02 2360 18485 0.5212 1.03 0.939,1.13 467 4653
414.2 ASCVD circulatory system Both 0.6266 1.02 0.933,1.12 492 4846 0.5212 1.03 0.939,1.13 467 4653
415 Pulmonary heart disease circulatory system Both 0.9616 1.0 0.962,1.04 2726 25061 0.9594 0.998 0.915,1.09 564 5674
415.1 Acute pulmonary heart disease circulatory system Both 0.7161 0.99 0.939,1.04 1510 15045 0.3963 0.976 0.924,1.03 1397 14462
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.7568 0.992 0.94,1.05 1507 15014 0.3963 0.976 0.924,1.03 1397 14462
415.2 Chronic pulmonary heart disease circulatory system Both 0.861 1.0 0.953,1.06 1506 14839 0.9594 0.998 0.915,1.09 564 5674
415.21 Primary pulmonary hypertension circulatory system Both 0.7413 0.986 0.906,1.07 592 5901 0.9594 0.998 0.915,1.09 564 5674
416 Cardiomegaly circulatory system Both 0.865 1.01 0.941,1.08 935 9293 0.9954 1.0 0.933,1.07 867 8946
418 Nonspecific chest pain circulatory system Both 0.3459 1.01 0.988,1.03 10015 28233 0.5984 1.02 0.956,1.08 1116 11421
418.1 Precordial pain circulatory system Both 0.6776 1.01 0.954,1.07 1193 11816 0.5984 1.02 0.956,1.08 1116 11421
420 Carditis circulatory system Both 0.2009 1.04 0.98,1.1 1275 12633 0.5164 1.03 0.944,1.12 568 5760
420.1 Myocarditis circulatory system Both 0.2449 1.15 0.909,1.45 76 752 0.335 1.13 0.882,1.45 67 718
420.2 Pericarditis circulatory system Both 0.2415 1.05 0.969,1.13 684 6830 0.2636 0.883 0.709,1.1 80 882
420.21 Acute pericarditis circulatory system Both 0.1334 0.878 0.74,1.04 144 1435 0.04721 0.835 0.698,0.998 130 1392
420.22 Chronic pericarditis circulatory system Both 0.257 0.887 0.721,1.09 92 912 0.2636 0.883 0.709,1.1 80 882
420.3 Endocarditis circulatory system Both 0.514 1.03 0.946,1.12 602 5990 0.5164 1.03 0.944,1.12 568 5760
425 Cardiomyopathy circulatory system Both 0.06546 0.953 0.905,1.0 1617 15758 0.6577 0.945 0.734,1.22 64 691
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.105 0.958 0.909,1.01 1557 15170 0.9572 0.995 0.839,1.18 147 1484
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.4457 0.941 0.805,1.1 171 1699 0.4227 0.937 0.8,1.1 165 1649
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.8913 1.01 0.857,1.19 154 1540 0.9572 0.995 0.839,1.18 147 1484
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.4345 1.05 0.925,1.2 248 2480 0.9226 1.01 0.876,1.16 211 2399
425.8 Other cardiomyopathy circulatory system Both 0.6761 0.95 0.747,1.21 71 709 0.6577 0.945 0.734,1.22 64 691
426 Cardiac conduction disorders circulatory system Both 0.4046 1.01 0.985,1.04 9881 21221 0.6918 0.983 0.903,1.07 594 5529
426.2 Atrioventricular [AV] block circulatory system Both 0.8204 1.01 0.953,1.06 1527 9610 0.5445 1.05 0.893,1.24 153 1442
426.21 First degree AV block circulatory system Both 0.8492 0.994 0.932,1.06 1064 7510 1.0 1.0 0.936,1.07 1003 7283
426.22 Mobitz II AV block circulatory system Both 0.1663 1.21 0.923,1.59 56 513 ,
426.23 Second degree AV block circulatory system Both 0.04519 1.18 1.0,1.38 161 1459 0.03112 1.2 1.02,1.41 151 1409
426.24 Atrioventricular block, complete circulatory system Both 0.9572 1.0 0.9,1.12 357 3041 0.9333 1.0 0.899,1.12 344 2936
426.25 Other heart block circulatory system Both 0.5848 1.05 0.891,1.23 161 1489 0.5445 1.05 0.893,1.24 153 1442
426.3 Bundle branch block circulatory system Both 0.06281 0.953 0.906,1.0 1775 11373 0.156 0.945 0.874,1.02 684 6024
426.31 Right bundle branch block circulatory system Both 0.05248 0.94 0.883,1.0 1101 8763 0.03236 0.932 0.874,0.994 1035 8494
426.32 Left bundle branch block circulatory system Both 0.2799 0.959 0.889,1.03 721 6217 0.156 0.945 0.874,1.02 684 6024
426.4 Anomalous atrioventricular excitation circulatory system Both 0.7907 0.965 0.744,1.25 62 611 0.7328 0.955 0.732,1.24 60 598
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.1352 1.02 0.994,1.05 8452 21094 0.2588 1.02 0.989,1.04 7970 20605
426.8 Other cardiac conduction disorders circulatory system Both 0.3855 0.959 0.872,1.05 456 4529 0.2979 0.949 0.859,1.05 409 4388
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.9311 0.997 0.94,1.06 1261 8802 0.6918 0.983 0.903,1.07 594 5529
426.91 Cardiac pacemaker in situ circulatory system Both 0.4677 0.974 0.906,1.05 836 6124 0.3606 0.966 0.897,1.04 792 5936
426.92 Cardiac defibrillator in situ circulatory system Both 0.5702 0.976 0.899,1.06 628 5698 0.6918 0.983 0.903,1.07 594 5529
427 Cardiac dysrhythmias circulatory system Both 0.09354 1.02 0.997,1.04 14018 21321 0.06902 1.04 0.997,1.07 3264 19678
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.3199 1.02 0.977,1.08 1882 14769 0.8892 0.995 0.927,1.07 837 7744
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.1901 1.04 0.981,1.1 1193 11216 0.3006 1.03 0.972,1.1 1128 10924
427.12 Paroxysmal ventricular tachycardia circulatory system Both 1.0 1.0 0.934,1.07 892 7975 0.8892 0.995 0.927,1.07 837 7744
427.2 Atrial fibrillation and flutter circulatory system Both 0.1644 1.03 0.99,1.06 4194 15493 0.01517 1.07 1.01,1.13 1504 9403
427.21 Atrial fibrillation circulatory system Both 0.2999 1.02 0.983,1.06 4097 15312 0.3581 1.02 0.98,1.06 3874 14903
427.22 Atrial flutter circulatory system Both 0.01374 1.07 1.01,1.13 1598 9674 0.01517 1.07 1.01,1.13 1504 9403
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.2046 1.02 0.99,1.05 7129 21276 0.2972 1.02 0.987,1.04 6704 20786
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.7031 1.02 0.923,1.13 419 4137 0.455 1.05 0.931,1.17 300 3104
427.41 Ventricular fibrillation and flutter circulatory system Both 0.9817 1.0 0.858,1.17 167 1670 0.8551 1.01 0.865,1.19 157 1611
427.42 Cardiac arrest circulatory system Both 0.6368 1.03 0.918,1.15 321 3186 0.455 1.05 0.931,1.17 300 3104
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.5649 1.01 0.979,1.04 5521 21271 0.787 1.0 0.973,1.04 5258 20781
427.6 Premature beats circulatory system Both 0.4074 1.02 0.972,1.07 1820 13218 0.9268 0.996 0.907,1.09 482 4722
427.61 Supraventricular premature beats circulatory system Both 0.9376 1.0 0.917,1.1 522 4879 0.9268 0.996 0.907,1.09 482 4722
427.7 Tachycardia NOS circulatory system Both 0.1972 1.02 0.988,1.06 3980 21286 0.1791 1.02 0.989,1.06 3718 20796
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.6531 1.02 0.943,1.1 738 6224 0.8375 1.01 0.932,1.09 697 6028
427.9 Palpitations circulatory system Both 0.05559 1.04 0.999,1.07 3420 20157 0.06902 1.04 0.997,1.07 3264 19678
428 Congestive heart failure; nonhypertensive circulatory system Both 0.2393 0.978 0.942,1.02 3326 19946 0.3819 0.973 0.916,1.03 1136 10234
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.1256 0.97 0.933,1.01 2965 19130 0.0375 0.958 0.92,0.998 2800 18490
428.2 Heart failure NOS circulatory system Both 0.2084 0.974 0.936,1.01 2781 17962 0.1002 0.966 0.926,1.01 2629 17361
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.2723 0.968 0.914,1.03 1288 11396 0.1706 0.959 0.904,1.02 1205 10990
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.5636 0.983 0.926,1.04 1208 10616 0.3819 0.973 0.916,1.03 1136 10234
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.4446 1.01 0.985,1.03 9394 27581 0.1858 0.944 0.866,1.03 556 5595
429.1 Heart transplant/surgery circulatory system Both 0.5768 0.98 0.913,1.05 823 8070 0.5458 0.978 0.91,1.05 791 7804
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.561 1.01 0.977,1.04 4445 23965 0.7079 1.01 0.973,1.04 4204 23218
429.3 Symptoms involving cardiovascular system circulatory system Both 0.4624 1.01 0.984,1.04 7147 27443 0.6457 1.01 0.98,1.03 6773 26656
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.125 0.937 0.862,1.02 591 5816 0.1858 0.944 0.866,1.03 556 5595
430 Intracranial hemorrhage circulatory system Both 0.4732 1.03 0.95,1.12 633 6305 0.6194 1.04 0.896,1.2 195 1923
430.1 Subarachnoid hemorrhage circulatory system Both 0.7311 1.02 0.897,1.17 230 2300 0.6577 1.03 0.902,1.18 221 2185
430.2 Intracerebral hemorrhage circulatory system Both 0.8551 1.01 0.901,1.13 314 3132 0.9441 1.0 0.892,1.13 298 2997
430.3 Subdural hemorrhage circulatory system Both 0.6855 1.03 0.891,1.19 202 2017 0.6194 1.04 0.896,1.2 195 1923
433 Cerebrovascular disease circulatory system Both 0.5458 1.01 0.978,1.04 4361 26660 0.8892 1.01 0.92,1.1 511 5098
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.1766 1.04 0.984,1.09 1533 12978 0.4977 0.912 0.699,1.19 58 572
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.4529 1.06 0.911,1.23 188 1858 0.5662 1.05 0.895,1.22 177 1778
433.12 Cerebral atherosclerosis circulatory system Both 0.3715 0.888 0.684,1.15 61 599 0.4977 0.912 0.699,1.19 58 572
433.2 Occlusion of cerebral arteries circulatory system Both 0.4966 1.02 0.97,1.07 1926 17593 0.4677 1.02 0.97,1.07 1774 16346
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.5433 1.01 0.968,1.06 1862 17011 0.4677 1.02 0.97,1.07 1774 16346
433.3 Cerebral ischemia circulatory system Both 0.7534 1.01 0.963,1.05 2122 18040 0.7816 1.01 0.958,1.06 1717 15427
433.31 Transient cerebral ischemia circulatory system Both 0.8453 1.0 0.957,1.05 1812 16062 0.7816 1.01 0.958,1.06 1717 15427
433.5 Cerebral aneurysm circulatory system Both 0.7852 1.01 0.917,1.12 408 4070 0.7178 1.02 0.92,1.13 391 3911
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.3614 0.953 0.859,1.06 383 3803 0.4624 0.961 0.863,1.07 360 3647
433.8 Late effects of cerebrovascular disease circulatory system Both 0.877 0.993 0.909,1.08 534 5286 0.8892 1.01 0.92,1.1 511 5098
440 Atherosclerosis circulatory system Both 0.2023 1.03 0.984,1.08 1946 16499 0.3162 1.04 0.962,1.13 660 6523
440.1 Atherosclerosis of renal artery circulatory system Both 0.3664 1.07 0.922,1.25 187 1855 0.4764 1.06 0.906,1.24 177 1779
440.2 Atherosclerosis of the extremities circulatory system Both 0.4753 1.02 0.962,1.09 1166 11265 0.6237 1.02 0.946,1.1 776 7673
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.8337 0.984 0.847,1.14 183 1815 0.7096 0.971 0.833,1.13 176 1741
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.618 1.02 0.948,1.09 812 7979 0.6237 1.02 0.946,1.1 776 7673
440.9 Atherosclerosis of aorta circulatory system Both 0.1726 1.05 0.977,1.14 702 6800 0.3162 1.04 0.962,1.13 660 6523
441 Vascular insufficiency of intestine circulatory system Both 0.3573 1.05 0.947,1.16 407 4039 0.7998 1.02 0.847,1.24 115 1162
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.3199 1.07 0.933,1.24 206 2025 0.2163 1.1 0.948,1.27 197 1955
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.5272 1.06 0.882,1.28 122 1207 0.7998 1.02 0.847,1.24 115 1162
442 Other aneurysm circulatory system Both 0.7516 1.01 0.964,1.05 2309 18098 0.8035 1.01 0.904,1.14 310 3154
442.1 Aortic aneurysm circulatory system Both 0.4786 1.02 0.968,1.07 1703 13812 0.1923 1.05 0.978,1.12 950 8640
442.11 Abdominal aortic aneurysm circulatory system Both 0.1469 1.05 0.983,1.12 992 9021 0.1923 1.05 0.978,1.12 950 8640
442.2 Aneurysm of iliac artery circulatory system Both 0.9397 0.994 0.857,1.15 177 1769 0.9441 0.995 0.855,1.16 169 1683
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.456 1.07 0.899,1.27 137 1357 0.3846 1.08 0.907,1.29 131 1303
442.4 Arterial dissection circulatory system Both 0.4236 0.938 0.801,1.1 156 1555 0.3508 0.926 0.787,1.09 149 1496
442.8 Aneurysm of other specified artery circulatory system Both 0.7228 1.02 0.912,1.14 330 3300 0.8035 1.01 0.904,1.14 310 3154
443 Peripheral vascular disease circulatory system Both 0.4055 1.02 0.976,1.06 2355 20353 0.5093 1.02 0.967,1.07 1668 14561
443.1 Raynaud's syndrome circulatory system Both 0.9141 0.995 0.916,1.08 608 6051 0.8974 0.994 0.914,1.08 592 5861
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.3673 0.924 0.779,1.1 141 1375 0.2877 0.91 0.764,1.08 137 1305
443.8 Other specified peripheral vascular diseases circulatory system Both 0.25 1.03 0.981,1.08 1899 17476 0.4677 1.02 0.97,1.07 1828 16816
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.2871 1.03 0.978,1.08 1747 15154 0.5093 1.02 0.967,1.07 1668 14561
444 Arterial embolism and thrombosis circulatory system Both 0.7586 0.988 0.913,1.07 675 6732 0.4111 1.08 0.899,1.3 121 1230
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.9954 1.0 0.875,1.14 240 2392 0.9099 0.992 0.866,1.14 229 2304
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.3972 1.08 0.904,1.29 129 1282 0.4111 1.08 0.899,1.3 121 1230
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.2642 1.06 0.955,1.18 367 3641 0.3177 1.07 0.934,1.23 214 2220
446.4 Wegener's granulomatosis circulatory system Both 0.171 1.17 0.936,1.45 86 857 0.15 1.18 0.942,1.48 82 828
446.5 Giant cell arteritis circulatory system Both 0.9954 1.0 0.775,1.29 59 547 0.9183 1.01 0.773,1.33 52 530
446.9 Arteritis NOS circulatory system Both 0.3837 1.06 0.928,1.22 230 2285 0.3177 1.07 0.934,1.23 214 2220
447 Other disorders of arteries and arterioles circulatory system Both 0.3027 1.02 0.979,1.07 2116 18819 0.05808 1.08 0.997,1.18 607 6067
447.1 Stricture of artery circulatory system Both 0.9638 0.998 0.904,1.1 435 4322 0.9162 0.995 0.898,1.1 411 4149
447.7 Aortic ectasia circulatory system Both 0.07798 1.08 0.992,1.17 637 6315 0.05808 1.08 0.997,1.18 607 6067
448 Disease of capillaries circulatory system Both 0.3112 0.964 0.899,1.03 853 8472 0.156 0.949 0.883,1.02 811 8153
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.3062 0.974 0.927,1.02 1701 17006 0.3206 0.974 0.924,1.03 1533 16415
451 Phlebitis and thrombophlebitis circulatory system Both 0.4508 0.968 0.888,1.05 582 5764 0.2495 0.913 0.783,1.07 180 1846
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.4898 0.949 0.817,1.1 190 1888 0.2495 0.913 0.783,1.07 180 1846
452 Other venous embolism and thrombosis circulatory system Both 0.6637 1.01 0.974,1.04 3773 25068 0.7691 1.03 0.846,1.25 115 1155
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.06637 0.881 0.77,1.01 228 2277 0.02393 0.851 0.74,0.979 213 2212
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.5534 1.01 0.972,1.05 2623 22444 0.8375 1.0 0.963,1.05 2453 21806
452.8 Postphlebitic syndrome circulatory system Both 0.778 1.03 0.848,1.25 119 1181 0.7691 1.03 0.846,1.25 115 1155
453 Chronic venous hypertension circulatory system Both 0.04236 0.85 0.726,0.994 173 1715 0.03083 0.837 0.713,0.984 166 1658
454 Varicose veins circulatory system Both 0.08974 0.963 0.921,1.01 2206 20243 0.1466 0.956 0.899,1.02 1134 11414
454.1 Varicose veins of lower extremity circulatory system Both 0.08851 0.96 0.916,1.01 1908 17574 0.1466 0.956 0.899,1.02 1134 11414
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.1479 0.957 0.901,1.02 1182 11754 0.1466 0.956 0.899,1.02 1134 11414
455 Hemorrhoids circulatory system Both 0.05224 1.03 1.0,1.07 4379 24588 0.06166 1.03 0.998,1.07 4147 23922
456 Chronic venous insufficiency [CVI] circulatory system Both 0.5984 0.988 0.947,1.03 2303 20367 0.4365 0.983 0.94,1.03 2188 19787
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.9162 1.0 0.956,1.05 1946 14131 0.8185 0.994 0.946,1.05 1738 13192
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.7534 0.981 0.87,1.11 287 2845 0.6194 0.969 0.856,1.1 272 2741
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.9772 1.0 0.953,1.05 1841 13661 0.8185 0.994 0.946,1.05 1738 13192
458 Hypotension circulatory system Both 0.6902 0.993 0.961,1.03 4073 28546 0.4677 0.987 0.952,1.02 3372 26604
458.1 Orthostatic hypotension circulatory system Both 0.2032 1.04 0.978,1.11 1031 10176 0.1871 1.05 0.978,1.12 950 9835
458.2 Iatrogenic hypotension circulatory system Both 0.2512 1.04 0.972,1.11 911 9084 0.4446 1.03 0.958,1.1 861 8743
458.9 Hypotension NOS circulatory system Both 0.5754 0.99 0.956,1.03 3641 27465 0.4677 0.987 0.952,1.02 3372 26604
459 Other disorders of circulatory system circulatory system Both 0.1202 1.03 0.993,1.06 3553 27674 0.05152 1.04 1.0,1.08 2622 22884
459.1 Hemorrhage NOS circulatory system Both 0.1982 1.06 0.972,1.15 619 6159 0.3436 1.04 0.957,1.14 577 5959
459.7 Blood vessel replaced circulatory system Both 0.6295 0.965 0.835,1.11 203 2030 0.5834 0.959 0.828,1.11 196 1951
459.9 Circulatory disease NEC circulatory system Both 0.05117 1.04 1.0,1.08 2757 23656 0.05152 1.04 1.0,1.08 2622 22884
464 Acute sinusitis respiratory Both 0.4699 1.01 0.978,1.05 3675 26562 0.561 1.01 0.975,1.05 3519 25748
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.01614 1.03 1.01,1.06 7223 30143 0.7261 0.98 0.877,1.1 330 3326
465.2 Acute pharyngitis respiratory Both 0.026 1.04 1.0,1.07 3967 26715 0.03908 1.04 1.0,1.07 3799 25914
465.4 Acute laryngitis and tracheitis respiratory Both 0.859 0.99 0.888,1.1 345 3441 0.7261 0.98 0.877,1.1 330 3326
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.2979 1.03 0.975,1.09 1431 14130 0.2793 1.03 0.975,1.09 1392 13758
471 Nasal polyps respiratory Both 0.8892 1.01 0.916,1.11 475 4727 0.9333 1.0 0.912,1.11 459 4595
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.7178 1.01 0.955,1.07 1344 13251 0.9977 1.0 0.944,1.06 1283 12845
473 Diseases of the larynx and vocal cords respiratory Both 0.4571 1.02 0.974,1.06 2393 20985 0.7709 1.01 0.959,1.06 1769 17467
473.1 Chronic laryngitis respiratory Both 0.5248 1.09 0.833,1.43 57 562 0.6592 1.06 0.806,1.4 55 542
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.9931 1.0 0.914,1.1 517 5167 0.7551 0.985 0.897,1.08 482 4999
473.4 Voice disturbance respiratory Both 0.5943 1.01 0.966,1.06 1880 18033 0.7709 1.01 0.959,1.06 1769 17467
474 Acute and chronic tonsillitis respiratory Both 0.4266 1.03 0.954,1.12 685 6193 0.8531 1.01 0.922,1.1 532 5063
474.1 Acute tonsillitis respiratory Both 0.2466 1.08 0.949,1.23 267 2507 0.3597 1.06 0.934,1.21 260 2466
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.6397 1.02 0.935,1.11 555 5166 0.8531 1.01 0.922,1.1 532 5063
475 Chronic sinusitis respiratory Both 0.5521 1.01 0.975,1.05 3434 23149 0.2858 1.05 0.963,1.13 624 6214
475.9 Postnasal drip respiratory Both 0.15 1.06 0.979,1.15 651 6441 0.2858 1.05 0.963,1.13 624 6214
476 Allergic rhinitis respiratory Both 0.07129 1.02 0.998,1.05 10205 23354 0.1114 1.02 0.996,1.04 9790 22694
477 Epistaxis or throat hemorrhage respiratory Both 0.03041 1.08 1.01,1.16 895 8841 0.07379 1.07 0.994,1.15 843 8569
478 Throat pain respiratory Both 0.7228 1.02 0.912,1.14 325 3233 0.9441 1.0 0.893,1.13 302 3149
479 Other upper respiratory disease respiratory Both 0.06546 1.03 0.998,1.06 4428 23338 0.1585 1.02 0.991,1.06 4186 22679
480 Pneumonia respiratory Both 0.4355 1.01 0.982,1.04 4823 30881 0.4236 0.919 0.747,1.13 101 1137
480.1 Bacterial pneumonia respiratory Both 0.4909 1.03 0.955,1.1 860 8567 0.4699 1.09 0.86,1.39 72 793
480.11 Pneumococcal pneumonia respiratory Both 0.5943 0.971 0.872,1.08 372 3720 0.7638 0.983 0.879,1.1 340 3587
480.12 Pseudomonal pneumonia respiratory Both 0.5902 0.95 0.788,1.15 121 1192 0.5808 0.946 0.778,1.15 110 1156
480.13 MRSA pneumonia respiratory Both 0.7551 1.04 0.828,1.3 82 818 0.4699 1.09 0.86,1.39 72 793
480.2 Viral pneumonia respiratory Both 0.3508 0.922 0.778,1.09 147 1461 0.6266 0.956 0.799,1.14 128 1405
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.2965 0.905 0.751,1.09 117 1170 0.2716 0.893 0.731,1.09 102 1129
480.5 Bronchopneumonia and lung abscess respiratory Both 0.6761 0.96 0.792,1.16 119 1175 0.4236 0.919 0.747,1.13 101 1137
481 Influenza respiratory Both 0.01089 1.09 1.02,1.16 990 9863 0.002979 1.11 1.04,1.18 928 9558
483 Acute bronchitis and bronchiolitis respiratory Both 0.1253 1.03 0.991,1.07 2615 24227 0.2193 1.03 0.985,1.07 2485 23495
495 Asthma respiratory Both 0.03034 1.03 1.0,1.06 6951 27725 0.01262 1.08 1.02,1.14 1211 12077
495.1 Chronic obstructive asthma respiratory Both 0.3069 0.944 0.846,1.05 341 3403 0.2188 1.18 0.906,1.54 58 573
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.2698 1.16 0.892,1.51 60 592 0.2188 1.18 0.906,1.54 58 573
495.2 Asthma with exacerbation respiratory Both 0.02113 1.07 1.01,1.14 1251 12442 0.01262 1.08 1.02,1.14 1211 12077
496 Chronic airway obstruction respiratory Both 0.7145 0.994 0.962,1.03 4444 23893 0.133 1.08 0.976,1.2 394 4166
496.1 Emphysema respiratory Both 0.1279 0.963 0.918,1.01 1831 16712 0.1409 0.963 0.916,1.01 1712 16079
496.2 Chronic bronchitis respiratory Both 0.811 0.996 0.96,1.03 3357 22668 0.8395 0.996 0.958,1.04 2898 20913
496.21 Obstructive chronic bronchitis respiratory Both 0.7145 0.993 0.956,1.03 3040 21701 0.8395 0.996 0.958,1.04 2898 20913
496.3 Bronchiectasis respiratory Both 0.1365 1.08 0.977,1.19 435 4329 0.133 1.08 0.976,1.2 394 4166
497 Bronchitis respiratory Both 0.9376 1.0 0.95,1.06 1481 14700 0.929 0.997 0.944,1.05 1405 14189
498 Acute bronchospasm respiratory Both 0.006012 1.16 1.04,1.29 376 3745 0.006653 1.16 1.04,1.29 364 3617
499 Cystic fibrosis respiratory Both 0.9528 0.994 0.821,1.2 116 1160 0.7015 1.04 0.852,1.27 106 1128
500 Lung disease due to external agents respiratory Both 0.5768 1.03 0.932,1.14 428 4273 0.7534 1.04 0.807,1.35 57 619
500.1 Extrinsic allergic alveolitis respiratory Both 0.09016 1.22 0.969,1.53 81 810 0.07943 1.24 0.975,1.56 77 780
500.2 Pneumoconiosis respiratory Both 0.6808 1.05 0.825,1.34 65 640 0.7534 1.04 0.807,1.35 57 619
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.7586 1.01 0.926,1.11 514 5078 0.9397 1.0 0.912,1.1 463 4911
502 Postinflammatory pulmonary fibrosis respiratory Both 0.7798 1.01 0.932,1.1 623 6192 0.597 1.02 0.939,1.12 558 5977
503 Pulmonary congestion and hypostasis respiratory Both 0.1702 1.06 0.977,1.14 690 6875 0.2489 1.05 0.968,1.14 644 6645
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.1282 1.08 0.978,1.19 447 4454 0.07586 1.13 0.987,1.3 223 2367
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.1972 1.09 0.956,1.24 247 2456 0.07586 1.13 0.987,1.3 223 2367
505 Other pulmonary inflamation or edema respiratory Both 0.8395 1.01 0.951,1.06 1352 13261 0.955 1.0 0.946,1.06 1273 12870
506 Empyema and pneumothorax respiratory Both 0.5861 0.989 0.949,1.03 2588 22332 0.5023 0.986 0.945,1.03 2369 21680
507 Pleurisy; pleural effusion respiratory Both 0.471 1.02 0.974,1.06 2415 21828 0.526 1.01 0.971,1.06 2190 21193
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.6761 1.01 0.965,1.06 2005 19256 0.6637 1.01 0.963,1.06 1833 18682
509 Respiratory failure, insufficiency, arrest respiratory Both 0.4345 0.985 0.948,1.02 3044 23898 0.3837 0.968 0.9,1.04 796 8206
509.1 Respiratory failure respiratory Both 0.631 1.01 0.96,1.07 1466 14560 0.7311 1.01 0.955,1.07 1359 14142
509.2 Respiratory insufficiency respiratory Both 0.1156 1.06 0.987,1.13 928 9238 0.1671 1.05 0.98,1.13 852 8960
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.2296 0.968 0.918,1.02 1500 14783 0.1462 0.96 0.909,1.01 1424 14325
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.5188 0.977 0.91,1.05 848 8472 0.3837 0.968 0.9,1.04 796 8206
510 Other diseases of lung respiratory Both 0.5117 1.01 0.98,1.04 4671 30168 0.8395 0.981 0.814,1.18 117 1225
510.2 Lung transplant respiratory Both 0.7727 0.974 0.814,1.16 128 1274 0.8395 0.981 0.814,1.18 117 1225
512 Other symptoms of respiratory system respiratory Both 0.1288 1.02 0.995,1.04 14878 23476 0.2234 1.02 0.99,1.04 8188 22928
512.1 Wheezing respiratory Both 0.1754 1.04 0.981,1.11 1071 10626 0.2183 1.04 0.976,1.11 1014 10348
512.2 Painful respiration respiratory Both 0.6353 1.01 0.964,1.06 1765 17029 0.7762 1.01 0.958,1.06 1654 16609
512.3 Abnormal chest sounds respiratory Both 0.3048 1.07 0.939,1.22 229 2261 0.4656 1.05 0.917,1.21 210 2195
512.7 Shortness of breath respiratory Both 0.157 1.02 0.993,1.05 7928 23452 0.3126 1.01 0.987,1.04 7452 22913
512.8 Cough respiratory Both 0.04315 1.03 1.0,1.06 7280 23469 0.05408 1.03 1.0,1.06 6861 22930
512.9 Other dyspnea respiratory Both 0.1225 1.02 0.995,1.05 8658 23467 0.2234 1.02 0.99,1.04 8188 22928
513 Respiratory abnormalities respiratory Both 0.1245 1.02 0.995,1.04 10231 28110 0.1009 1.13 0.976,1.32 187 1977
513.3 Hypoventilation respiratory Both 0.7063 1.02 0.936,1.1 618 6146 0.4027 1.07 0.908,1.27 147 1610
513.31 Apnea respiratory Both 0.9908 1.0 0.893,1.12 314 3136 0.8375 1.01 0.903,1.13 308 3047
513.32 Orthopnea respiratory Both 0.4256 1.07 0.911,1.25 167 1662 0.4027 1.07 0.908,1.27 147 1610
513.4 Hyperventilation respiratory Both 0.743 0.984 0.891,1.09 440 4383 0.8279 0.989 0.893,1.1 407 4233
513.8 Disorders of diaphragm respiratory Both 0.1396 1.11 0.965,1.29 206 2053 0.1009 1.13 0.976,1.32 187 1977
514 Abnormal findings examination of lungs respiratory Both 0.01452 1.04 1.01,1.07 4486 29229 0.04335 1.05 1.0,1.09 2237 22019
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.7998 0.981 0.844,1.14 193 1914 0.8872 0.989 0.847,1.15 181 1864
514.2 Solitary pulmonary nodule respiratory Both 0.02844 1.05 1.0,1.09 2489 22668 0.04335 1.05 1.0,1.09 2237 22019
516 Abnormal sputum respiratory Both 0.8299 0.991 0.908,1.08 565 5640 0.9727 1.0 0.907,1.11 428 4553
516.1 Hemoptysis respiratory Both 0.9484 0.997 0.907,1.1 473 4720 0.9727 1.0 0.907,1.11 428 4553
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.3311 1.01 0.985,1.05 5153 32053 0.4477 1.01 0.979,1.05 3714 28301
519.1 Tracheostomy complications respiratory Both 0.9484 1.01 0.863,1.17 176 1760 0.6095 0.96 0.821,1.12 167 1710
519.2 Respiratory complications respiratory Both 0.9419 1.0 0.901,1.12 370 3696 0.7852 0.985 0.881,1.1 349 3587
519.8 Other diseases of respiratory system, NEC respiratory Both 0.7762 1.01 0.943,1.08 887 8857 0.7516 1.01 0.943,1.09 845 8573
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.3483 1.02 0.983,1.05 4043 29199 0.4477 1.01 0.979,1.05 3714 28301
520 Disorders of tooth development digestive Both 0.04436 0.884 0.783,0.997 291 2900 0.2265 0.909 0.779,1.06 169 1650
520.1 Hereditary disturbances in tooth structure digestive Both 0.3062 0.912 0.764,1.09 131 1301 0.1167 0.865 0.721,1.04 126 1252
520.2 Disturbances in tooth eruption digestive Both 0.2113 0.907 0.778,1.06 172 1693 0.2265 0.909 0.779,1.06 169 1650
521 Diseases of hard tissues of teeth digestive Both 0.879 0.994 0.921,1.07 719 7167 0.5521 0.976 0.899,1.06 628 6500
521.1 Dental caries digestive Both 0.8222 0.991 0.916,1.07 673 6709 0.5521 0.976 0.899,1.06 628 6500
522 Diseases of pulp and periapical tissues digestive Both 0.4198 1.04 0.942,1.16 408 4067 0.4831 1.04 0.928,1.17 316 3298
522.5 Periapical abscess digestive Both 0.4943 1.04 0.93,1.16 341 3404 0.4831 1.04 0.928,1.17 316 3298
523 Gingival and periodontal diseases digestive Both 0.6442 0.98 0.899,1.07 569 5690 0.7112 1.04 0.847,1.27 96 991
523.1 Gingivitis digestive Both 0.2799 1.11 0.921,1.33 117 1163 0.1442 1.15 0.953,1.39 107 1130
523.3 Periodontitis (acute or chronic) digestive Both 0.5702 0.966 0.856,1.09 294 2940 0.7112 1.04 0.847,1.27 96 991
523.31 Acute periodontitis digestive Both 0.7178 0.976 0.856,1.11 251 2510 0.8933 0.991 0.865,1.13 235 2427
523.32 Chronic periodontitis digestive Both 0.871 1.02 0.834,1.24 103 1030 0.7112 1.04 0.847,1.27 96 991
524 Dentofacial anomalies, including malocclusion digestive Both 0.4395 1.05 0.932,1.18 308 3080 0.1059 1.13 0.975,1.31 183 1812
524.3 Anomalies of tooth position/malocclusion digestive Both 0.1119 1.13 0.973,1.3 186 1856 0.1059 1.13 0.975,1.31 183 1812
525 Other diseases of the teeth and supporting structures digestive Both 0.2178 0.957 0.892,1.03 853 8530 0.537 0.963 0.855,1.09 300 3082
525.1 Loss of teeth or edentulism digestive Both 0.863 0.99 0.882,1.11 318 3178 0.537 0.963 0.855,1.09 300 3082
526 Diseases of the jaws digestive Both 0.3475 1.02 0.977,1.07 2140 21162 0.6252 1.03 0.924,1.14 378 3839
526.1 Cysts of the jaws digestive Both 0.1858 0.908 0.788,1.05 213 2123 0.2123 0.913 0.792,1.05 212 2057
526.3 Anomalies of jaw size/symmetry digestive Both 0.2773 1.08 0.939,1.24 206 2052 0.3236 1.07 0.932,1.24 205 1996
526.4 Temporomandibular joint disorders digestive Both 0.3126 1.03 0.971,1.1 1178 11779 0.5346 1.03 0.944,1.12 589 5829
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.4764 1.02 0.958,1.1 941 9410 0.4677 1.03 0.958,1.1 918 9139
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.4295 1.03 0.951,1.13 600 5993 0.5346 1.03 0.944,1.12 589 5829
526.5 Inflammatory conditions of jaw digestive Both 0.9162 0.993 0.871,1.13 242 2405 0.6237 0.967 0.845,1.11 227 2318
526.9 Jaw disease NOS digestive Both 0.2877 1.06 0.954,1.17 399 3982 0.6252 1.03 0.924,1.14 378 3839
527 Diseases of the salivary glands digestive Both 0.07516 1.05 0.995,1.11 1362 13604 0.3945 0.934 0.799,1.09 177 1894
527.2 Sialoadenitis digestive Both 0.9057 0.993 0.885,1.11 320 3200 0.8241 0.987 0.877,1.11 301 3099
527.7 Disturbance of salivary secretion digestive Both 0.008954 1.11 1.03,1.2 715 7141 0.02667 1.1 1.01,1.19 643 6871
527.8 Other specified diseases of the salivary glands digestive Both 0.5383 0.954 0.821,1.11 196 1960 0.3945 0.934 0.799,1.09 177 1894
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.4775 1.02 0.972,1.06 2077 20750 0.7096 0.966 0.805,1.16 129 1282
528.1 Stomatitis and mucositis digestive Both 0.8356 1.01 0.925,1.1 536 5360 0.5248 1.05 0.898,1.23 161 1655
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.6776 1.03 0.884,1.21 165 1650 0.561 1.05 0.888,1.25 141 1587
528.12 Oral aphthae digestive Both 0.5623 1.05 0.897,1.22 170 1700 0.5248 1.05 0.898,1.23 161 1655
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.7551 1.02 0.882,1.19 185 1837 0.6561 1.04 0.887,1.21 173 1783
528.4 Cysts of oral soft tissues digestive Both 0.8185 1.02 0.838,1.25 110 1096 0.5888 1.08 0.825,1.4 62 659
528.41 Cyst of the salivary gland digestive Both 0.7211 1.05 0.812,1.35 68 679 0.5888 1.08 0.825,1.4 62 659
528.5 Diseases of lips digestive Both 0.9268 1.01 0.9,1.12 334 3340 0.9333 0.995 0.887,1.12 311 3227
528.6 Leukoplakia of oral mucosa digestive Both 0.9057 0.989 0.817,1.2 113 1120 0.7568 1.03 0.847,1.26 106 1074
528.7 Sialolithiasis digestive Both 0.865 0.985 0.822,1.18 132 1320 0.7096 0.966 0.805,1.16 129 1282
529 Diseases and other conditions of the tongue digestive Both 0.5495 1.03 0.941,1.12 541 5402 0.8204 0.979 0.815,1.18 123 1301
529.1 Glossitis digestive Both 0.1726 1.15 0.942,1.4 99 982 0.2844 1.12 0.912,1.37 93 943
529.6 Glossodynia digestive Both 0.9863 0.998 0.838,1.19 136 1355 0.8204 0.979 0.815,1.18 123 1301
530 Diseases of esophagus digestive Both 0.869 0.998 0.977,1.02 13874 23034 0.8531 1.01 0.946,1.07 1141 11607
530.1 Esophagitis, GERD and related diseases digestive Both 0.9594 1.0 0.979,1.02 13419 23031 0.1622 0.884 0.744,1.05 139 1406
530.11 GERD digestive Both 0.912 1.0 0.98,1.02 13059 23031 0.9441 0.999 0.977,1.02 12474 22439
530.12 Ulcer of esophagus digestive Both 0.1799 0.921 0.818,1.04 298 2973 0.1285 0.909 0.803,1.03 280 2883
530.13 Barrett's esophagus digestive Both 0.1828 0.944 0.868,1.03 609 6080 0.1589 0.939 0.861,1.02 566 5872
530.14 Reflux esophagitis digestive Both 0.6471 1.01 0.96,1.07 1483 14213 0.8128 1.01 0.953,1.06 1398 13762
530.15 Eosinophilic esophagitis digestive Both 0.06012 0.85 0.718,1.01 145 1441 0.1622 0.884 0.744,1.05 139 1406
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.7244 0.983 0.895,1.08 475 4742 0.7413 0.984 0.894,1.08 454 4604
530.3 Stricture and stenosis of esophagus digestive Both 0.2944 0.961 0.892,1.04 752 7474 0.2254 0.954 0.883,1.03 709 7226
530.5 Disorders of esophageal motility digestive Both 0.6368 1.02 0.928,1.13 434 4326 0.869 1.01 0.912,1.12 418 4181
530.6 Diverticulum of esophagus, acquired digestive Both 0.9772 0.997 0.833,1.19 121 1181 0.9247 0.991 0.828,1.19 119 1140
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.743 1.04 0.817,1.33 70 700 0.9977 1.0 0.78,1.28 66 676
530.9 Heartburn digestive Both 0.6966 1.01 0.953,1.07 1198 11946 0.8531 1.01 0.946,1.07 1141 11607
531 Peptic ulcer (excl. esophageal) digestive Both 0.6209 1.01 0.963,1.07 1608 16066 0.6295 1.05 0.863,1.28 103 1099
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.4786 1.04 0.929,1.17 311 3103 0.4943 1.04 0.925,1.17 288 2985
531.2 Gastric ulcer digestive Both 0.857 1.01 0.939,1.08 884 8834 0.9616 1.0 0.933,1.08 837 8530
531.3 Duodenal ulcer digestive Both 0.8241 1.01 0.91,1.13 362 3613 0.9795 1.0 0.897,1.12 334 3481
531.4 Peptic ulcer, site unspecified digestive Both 0.8279 1.01 0.93,1.09 632 6313 0.8492 1.01 0.927,1.1 591 6068
531.5 Gastrojejunal ulcer digestive Both 0.9954 1.0 0.829,1.21 115 1143 0.6295 1.05 0.863,1.28 103 1099
532 Dysphagia digestive Both 0.5534 0.99 0.958,1.02 4457 22190 0.2965 0.982 0.95,1.02 4178 21607
535 Gastritis and duodenitis digestive Both 0.4898 1.02 0.972,1.06 2129 21208 0.9141 1.0 0.938,1.07 922 9498
535.1 Acute gastritis digestive Both 0.875 1.01 0.936,1.08 814 8139 0.9016 1.0 0.933,1.08 767 7877
535.2 Atrophic gastritis digestive Both 0.4236 1.05 0.926,1.2 250 2500 0.4315 1.06 0.923,1.21 235 2418
535.6 Duodenitis digestive Both 0.3631 1.06 0.935,1.2 265 2650 0.2972 1.07 0.942,1.22 252 2562
535.8 Other specified gastritis digestive Both 0.873 0.993 0.906,1.09 497 4964 0.9141 1.01 0.915,1.1 469 4789
535.9 Gastritis and duodenitis, NOS digestive Both 0.9268 1.0 0.939,1.07 985 9835 0.9141 1.0 0.938,1.07 922 9498
536 Disorders of function of stomach digestive Both 0.3214 1.02 0.979,1.07 2251 22311 0.6902 0.99 0.94,1.04 1595 16268
536.3 Gastroparesis digestive Both 0.7413 1.02 0.926,1.11 489 4876 0.7516 1.02 0.924,1.12 468 4730
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.4487 1.04 0.934,1.17 334 3331 0.7943 1.02 0.906,1.14 316 3219
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.865 1.0 0.955,1.06 1699 16834 0.6902 0.99 0.94,1.04 1595 16268
537 Other disorders of stomach and duodenum digestive Both 0.6546 1.01 0.968,1.05 2357 23199 0.537 0.943 0.783,1.14 116 1219
537.1 Lesions of stomach and duodenum digestive Both 0.5902 0.952 0.797,1.14 128 1271 0.537 0.943 0.783,1.14 116 1219
539 Bariatric surgery digestive Both 0.4539 1.02 0.963,1.09 1118 11180 0.4436 1.02 0.963,1.09 1091 10801
540 Appendiceal conditions digestive Both 0.9506 1.0 0.905,1.11 399 3990 0.871 0.99 0.876,1.12 284 2831
540.1 Appendicitis digestive Both 0.9078 0.994 0.89,1.11 349 3490 0.871 0.99 0.876,1.12 284 2831
540.11 Acute appendicitis digestive Both 0.6792 0.975 0.864,1.1 293 2930 0.871 0.99 0.876,1.12 284 2831
550 Abdominal hernia digestive Both 0.984 1.0 0.972,1.03 5517 31191 0.8414 0.994 0.933,1.06 1054 10562
550.1 Inguinal hernia digestive Both 0.9247 0.997 0.944,1.05 1427 13556 0.8337 0.994 0.94,1.05 1360 13030
550.2 Diaphragmatic hernia digestive Both 0.5943 0.988 0.946,1.03 2290 21266 0.3475 0.979 0.937,1.02 2181 20446
550.3 Femoral hernia digestive Both 0.1923 1.14 0.937,1.38 109 1082 0.2805 1.12 0.913,1.37 103 1033
550.4 Umbilical hernia digestive Both 0.9036 0.996 0.934,1.06 1053 10514 0.8035 0.992 0.929,1.06 1012 10128
550.5 Ventral hernia digestive Both 0.9441 0.998 0.952,1.05 1826 18190 0.7889 1.01 0.959,1.06 1759 17483
550.6 Incisional hernia digestive Both 0.5585 0.982 0.923,1.04 1101 10999 0.8414 0.994 0.933,1.06 1054 10562
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.4539 0.978 0.924,1.04 1275 12527 0.7345 0.983 0.889,1.09 426 4265
555.1 Regional enteritis digestive Both 0.975 0.999 0.928,1.08 775 7701 0.8166 0.991 0.92,1.07 755 7548
555.2 Ulcerative colitis digestive Both 0.7396 0.988 0.917,1.06 768 7591 0.7345 0.983 0.889,1.09 426 4265
555.21 Ulcerative colitis (chronic) digestive Both 0.7413 0.983 0.89,1.09 438 4361 0.7345 0.983 0.889,1.09 426 4265
556 Ulceration of the lower GI tract digestive Both 0.861 1.01 0.918,1.11 473 4719 0.02642 1.21 1.02,1.44 133 1443
556.1 Ulceration of intestine digestive Both 0.2754 1.06 0.957,1.17 412 4099 0.02642 1.21 1.02,1.44 133 1443
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.01742 1.22 1.03,1.43 152 1496 0.02642 1.21 1.02,1.44 133 1443
557 Intestinal malabsorption (non-celiac) digestive Both 0.8551 1.01 0.949,1.06 1306 12565 0.6699 0.974 0.863,1.1 293 2978
557.1 Celiac disease digestive Both 0.6223 0.971 0.862,1.09 305 3050 0.6699 0.974 0.863,1.1 293 2978
558 Noninfectious gastroenteritis digestive Both 0.4477 1.02 0.976,1.06 2706 20417 0.3882 1.02 0.977,1.06 2575 19948
559 Ileostomy status digestive Both 0.05929 1.07 0.997,1.16 773 7702 0.1239 1.06 0.984,1.14 753 7501
560 Intestinal obstruction without mention of hernia digestive Both 0.6966 1.01 0.968,1.05 2580 20303 0.2624 1.03 0.977,1.09 1389 14000
560.1 Paralytic ileus digestive Both 0.2698 1.03 0.976,1.09 1429 13524 0.3741 1.03 0.97,1.08 1346 13156
560.2 Impaction of intestine digestive Both 0.4256 0.95 0.837,1.08 257 2499 0.4613 0.953 0.839,1.08 250 2430
560.3 Peritoneal or intestinal adhesions digestive Both 0.879 0.99 0.874,1.12 261 2599 0.9795 0.998 0.876,1.14 239 2517
560.4 Other intestinal obstruction digestive Both 0.3083 1.03 0.975,1.08 1489 14381 0.2624 1.03 0.977,1.09 1389 14000
561 Symptoms involving digestive system digestive Both 0.138 1.02 0.994,1.05 7750 22039 0.2606 1.03 0.981,1.07 2242 18542
561.1 Diarrhea digestive Both 0.2553 1.02 0.988,1.05 5986 22042 0.2786 1.02 0.987,1.05 5605 21541
561.2 Flatulence digestive Both 0.241 1.03 0.983,1.07 2358 18995 0.2606 1.03 0.981,1.07 2242 18542
562 Diverticulosis and diverticulitis digestive Both 0.007228 1.04 1.01,1.08 5014 18500 0.2239 1.04 0.978,1.1 1239 11892
562.1 Diverticulosis digestive Both 0.006442 1.05 1.01,1.08 4973 18448 0.01409 1.04 1.01,1.08 4699 17976
562.2 Diverticulitis digestive Both 0.1199 1.05 0.988,1.11 1292 12242 0.2239 1.04 0.978,1.1 1239 11892
563 Constipation digestive Both 0.2415 1.02 0.988,1.05 5639 22004 0.4457 1.01 0.982,1.04 5292 21503
564 Functional digestive disorders digestive Both 0.3062 1.01 0.988,1.04 9553 22037 0.8054 1.01 0.957,1.06 1680 16103
564.1 Irritable Bowel Syndrome digestive Both 0.7621 1.01 0.966,1.05 2751 17147 0.8072 1.01 0.964,1.05 2659 16746
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.9954 1.0 0.958,1.04 2348 18710 0.9311 0.998 0.954,1.04 2159 18241
564.9 Personal history of diseases of digestive system digestive Both 0.5715 1.01 0.966,1.07 1762 16521 0.8054 1.01 0.957,1.06 1680 16103
565 Anal and rectal conditions digestive Both 0.6808 1.01 0.968,1.05 2533 24500 0.2594 1.04 0.971,1.12 870 8966
565.1 Anal and rectal polyp digestive Both 0.3648 1.03 0.965,1.1 932 9300 0.2594 1.04 0.971,1.12 870 8966
567 Peritonitis and retroperitoneal infections digestive Both 0.009616 1.08 1.02,1.15 1149 11482 0.01782 1.08 1.01,1.15 1089 11118
568 Other disorders of peritoneum digestive Both 0.3516 1.03 0.972,1.08 1452 14494 0.6412 1.02 0.952,1.08 1029 10380
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.7691 1.01 0.948,1.07 1076 10752 0.6412 1.02 0.952,1.08 1029 10380
569 Other disorders of intestine digestive Both 0.8337 1.0 0.976,1.03 6343 29512 0.9572 0.998 0.939,1.06 1144 11696
569.1 Toxic gastroenteritis and colitis digestive Both 0.1799 1.1 0.959,1.25 251 2510 0.3396 1.07 0.928,1.24 210 2431
569.2 Gastrointestinal complications digestive Both 0.8337 1.01 0.948,1.07 1206 12058 0.9572 0.998 0.939,1.06 1144 11696
571 Chronic liver disease and cirrhosis digestive Both 0.7709 0.995 0.961,1.03 3603 27394 0.1148 0.923 0.835,1.02 414 4282
571.5 Other chronic nonalcoholic liver disease digestive Both 0.9057 1.0 0.967,1.04 3388 27100 0.3381 0.964 0.894,1.04 739 7591
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.2786 0.96 0.893,1.03 781 7802 0.3381 0.964 0.894,1.04 739 7591
571.6 Primary biliary cirrhosis digestive Both 0.7328 1.03 0.87,1.22 146 1460 0.7534 1.03 0.864,1.22 137 1427
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.03304 0.922 0.855,0.993 749 7472 0.1148 0.923 0.835,1.02 414 4282
571.81 Portal hypertension digestive Both 0.1435 0.93 0.844,1.02 441 4400 0.1148 0.923 0.835,1.02 414 4282
572 Ascites (non malignant) digestive Both 0.1963 1.03 0.984,1.08 1884 18805 0.2208 1.03 0.982,1.08 1756 18292
573 Other disorders of liver digestive Both 0.7762 0.995 0.964,1.03 4460 28151 0.9247 0.998 0.962,1.04 3134 27311
573.1 Chronic passive congestion of liver digestive Both 0.5998 0.947 0.773,1.16 100 991 0.7621 0.968 0.786,1.19 94 971
573.2 Liver replaced by transplant digestive Both 0.9817 0.998 0.873,1.14 227 2268 0.9376 0.994 0.865,1.14 210 2197
573.3 Hepatomegaly digestive Both 0.6039 0.971 0.87,1.08 337 3368 0.7178 0.979 0.874,1.1 311 3282
573.4 Acute and subacute necrosis of liver digestive Both 0.2851 0.932 0.82,1.06 258 2580 0.1968 0.916 0.801,1.05 238 2520
573.5 Jaundice (not of newborn) digestive Both 0.3828 1.03 0.96,1.11 758 7555 0.4732 1.03 0.952,1.11 692 7334
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.6081 0.988 0.943,1.03 1973 19683 0.8395 0.995 0.949,1.04 1845 19179
573.7 Abnormal results of function study of liver digestive Both 0.4808 1.02 0.972,1.06 2110 21014 0.5689 1.01 0.968,1.06 1975 20436
573.9 Abnormal serum enzyme levels digestive Both 0.9772 1.0 0.964,1.04 3345 28043 0.9247 0.998 0.962,1.04 3134 27311
574 Cholelithiasis and cholecystitis digestive Both 0.05888 1.04 0.999,1.08 2610 25589 0.2051 1.05 0.971,1.14 628 6440
574.1 Cholelithiasis digestive Both 0.06982 1.04 0.997,1.08 2391 23829 0.2805 1.06 0.956,1.17 434 4289
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.4819 1.05 0.921,1.19 260 2580 0.507 1.05 0.917,1.19 245 2491
574.12 Cholelithiasis with other cholecystitis digestive Both 0.2559 1.06 0.96,1.17 444 4434 0.2805 1.06 0.956,1.17 434 4289
574.2 Calculus of bile duct digestive Both 0.05236 1.08 0.999,1.17 696 6939 0.04487 1.09 1.0,1.18 672 6699
574.3 Cholecystitis without cholelithiasis digestive Both 0.1656 1.06 0.977,1.15 667 6662 0.2051 1.05 0.971,1.14 628 6440
575 Other biliary tract disease digestive Both 0.7709 0.993 0.947,1.04 1868 18668 0.2307 0.908 0.776,1.06 174 1803
575.1 Cholangitis digestive Both 0.2958 0.94 0.837,1.06 310 3089 0.1236 0.909 0.804,1.03 283 2975
575.2 Obstruction of bile duct digestive Both 0.8222 1.01 0.924,1.1 530 5291 0.6668 0.98 0.893,1.07 488 5111
575.6 Cholesterolosis of gallbladder digestive Both 0.4753 1.06 0.902,1.25 168 1680 0.4688 1.06 0.9,1.26 159 1632
575.7 Other disorders of gallbladder digestive Both 0.6745 0.985 0.915,1.06 773 7719 0.5559 0.978 0.908,1.05 743 7470
575.8 Other disorders of biliary tract digestive Both 0.3864 0.972 0.911,1.04 996 9950 0.1837 0.956 0.894,1.02 932 9603
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.2606 0.917 0.789,1.07 188 1880 0.2307 0.908 0.776,1.06 174 1803
577 Diseases of pancreas digestive Both 0.7129 0.991 0.945,1.04 1842 18379 0.1483 0.93 0.842,1.03 428 4375
577.1 Acute pancreatitis digestive Both 0.399 0.972 0.91,1.04 967 9651 0.3664 0.969 0.906,1.04 918 9319
577.2 Chronic pancreatitis digestive Both 0.008017 0.871 0.787,0.965 396 3955 0.005984 0.863 0.777,0.959 372 3824
577.3 Cyst and pseudocyst of pancreas digestive Both 0.1122 0.926 0.842,1.02 462 4557 0.1483 0.93 0.842,1.03 428 4375
578 Gastrointestinal hemorrhage digestive Both 0.3041 1.02 0.984,1.05 3572 30460 0.984 0.999 0.941,1.06 1146 11872
578.1 Hematemesis digestive Both 0.9141 0.994 0.895,1.1 383 3821 0.9727 0.998 0.896,1.11 365 3724
578.2 Blood in stool digestive Both 0.9683 1.0 0.958,1.05 2156 21196 0.6714 1.01 0.965,1.06 2024 20536
578.8 Hemorrhage of rectum and anus digestive Both 0.6871 1.01 0.961,1.06 1718 17070 0.865 1.0 0.955,1.06 1626 16563
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.8453 1.01 0.949,1.07 1238 12280 0.984 0.999 0.941,1.06 1146 11872
579 Other symptoms involving abdomen and pelvis digestive Both 0.5957 0.991 0.958,1.03 3750 28690 0.2275 1.04 0.974,1.12 943 9548
579.2 Splenomegaly digestive Both 0.8072 1.01 0.929,1.1 593 5923 0.9226 0.996 0.91,1.09 510 5758
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.1542 1.05 0.982,1.12 998 9882 0.2275 1.04 0.974,1.12 943 9548
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.3373 1.03 0.971,1.09 1264 12626 0.5333 1.04 0.919,1.18 265 2661
580.1 Glomerulonephritis genitourinary Both 0.5957 0.97 0.865,1.09 324 3228 0.7345 0.977 0.852,1.12 219 2218
580.11 Proliferative glomerulonephritis genitourinary Both 0.879 1.02 0.837,1.23 114 1140 0.6561 1.05 0.858,1.28 108 1119
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.787 1.03 0.829,1.28 92 905 0.4753 1.09 0.867,1.36 87 884
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.5546 0.961 0.841,1.1 232 2298 0.7345 0.977 0.852,1.12 219 2218
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.3126 1.09 0.926,1.27 167 1670 0.2051 1.11 0.944,1.31 157 1628
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.2323 1.04 0.974,1.11 943 9430 0.2123 1.06 0.966,1.17 475 4847
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.26 1.05 0.963,1.15 554 5535 0.3177 1.05 0.957,1.14 531 5359
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.2985 1.05 0.957,1.15 500 4995 0.2123 1.06 0.966,1.17 475 4847
580.4 Renal sclerosis, NOS genitourinary Both 0.4519 1.05 0.928,1.18 275 2750 0.5333 1.04 0.919,1.18 265 2661
585 Renal failure genitourinary Both 0.8166 1.0 0.975,1.03 5756 27307 0.3926 1.03 0.96,1.11 797 8109
585.1 Acute renal failure genitourinary Both 0.955 0.999 0.963,1.04 3278 22851 0.6776 0.992 0.955,1.03 3051 22167
585.2 Renal failure NOS genitourinary Both 0.6353 0.981 0.907,1.06 688 6872 0.6683 0.982 0.906,1.07 648 6639
585.3 Chronic renal failure [CKD] genitourinary Both 0.873 1.0 0.97,1.04 4216 24655 0.6397 0.981 0.907,1.06 675 6806
585.31 Renal dialysis genitourinary Both 0.4603 0.967 0.886,1.06 543 5430 0.5495 0.973 0.89,1.06 521 5266
585.32 End stage renal disease genitourinary Both 0.9036 1.0 0.933,1.08 773 7730 0.7889 1.01 0.937,1.09 738 7496
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.9886 1.0 0.957,1.04 2272 17155 0.912 0.997 0.953,1.04 2140 16610
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.5888 0.979 0.906,1.06 707 7038 0.6397 0.981 0.907,1.06 675 6806
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.2183 1.05 0.974,1.12 851 8381 0.3926 1.03 0.96,1.11 797 8109
586 Other disorders of the kidney and ureters genitourinary Both 0.3076 1.01 0.987,1.04 6202 28774 0.873 0.996 0.943,1.05 1467 14214
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.955 1.0 0.89,1.13 284 2825 0.3532 1.1 0.902,1.33 110 1083
586.11 Small kidney genitourinary Both 0.2438 0.909 0.774,1.07 165 1642 0.2084 0.901 0.766,1.06 161 1598
586.12 Vesicoureteral reflux genitourinary Both 0.1919 1.14 0.937,1.38 112 1120 0.3532 1.1 0.902,1.33 110 1083
586.2 Cyst of kidney, acquired genitourinary Both 0.6808 1.01 0.954,1.08 1170 11069 0.929 1.0 0.942,1.07 1069 10688
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.4315 0.936 0.794,1.1 148 1470 0.3715 0.926 0.782,1.1 141 1427
586.4 Stricture/obstruction of ureter genitourinary Both 0.9683 0.999 0.948,1.05 1536 14675 0.873 0.996 0.943,1.05 1467 14214
587 Kidney replaced by transpant genitourinary Both 0.7798 0.988 0.909,1.07 612 6120 0.9727 1.0 0.919,1.09 580 5932
588 Disorders resulting from impaired renal function genitourinary Both 0.4943 0.973 0.9,1.05 701 7004 0.3819 0.96 0.876,1.05 497 5080
588.1 Renal osteodystrophy genitourinary Both 0.5585 1.04 0.909,1.19 227 2267 0.4864 1.05 0.915,1.21 220 2184
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.3483 0.958 0.876,1.05 525 5241 0.3819 0.96 0.876,1.05 497 5080
589 Abnormal results of function study of kidney genitourinary Both 0.7638 1.01 0.942,1.09 840 8370 0.695 1.01 0.943,1.09 790 8113
590 Pyelonephritis genitourinary Both 0.04898 1.06 1.0,1.13 1161 11597 0.05152 1.06 1.0,1.13 1108 11225
591 Urinary tract infection genitourinary Both 0.3963 1.01 0.986,1.04 8020 27291 0.4645 1.01 0.984,1.04 7677 26418
592 Cystitis and urethritis genitourinary Both 0.7691 0.993 0.951,1.04 2264 19423 0.5152 0.944 0.793,1.12 140 1377
592.1 Cystitis genitourinary Both 0.8375 0.995 0.952,1.04 2149 18531 0.4457 0.958 0.858,1.07 349 3432
592.11 Acute cystitis genitourinary Both 0.2761 0.968 0.914,1.03 1256 12111 0.4989 0.98 0.923,1.04 1189 11690
592.12 Chronic cystitis genitourinary Both 0.7816 1.02 0.885,1.18 199 1972 0.7907 1.02 0.882,1.18 193 1895
592.13 Chronic interstitial cystitis genitourinary Both 0.3855 0.953 0.854,1.06 354 3540 0.4457 0.958 0.858,1.07 349 3432
592.2 Urethritis and urethral syndrome genitourinary Both 0.4645 0.938 0.789,1.11 143 1430 0.5152 0.944 0.793,1.12 140 1377
593 Hematuria genitourinary Both 0.04093 1.04 1.0,1.07 3848 26566 0.2844 1.04 0.965,1.13 692 6981
593.1 Gross hematuria genitourinary Both 0.881 0.995 0.938,1.06 1201 11351 0.8072 0.992 0.933,1.06 1129 10906
593.2 Microscopic hematuria genitourinary Both 0.2061 1.05 0.973,1.14 724 7225 0.2844 1.04 0.965,1.13 692 6981
594 Urinary calculus genitourinary Both 0.8147 1.0 0.975,1.03 5516 31876 1.0 1.0 0.883,1.13 278 2773
594.1 Calculus of kidney genitourinary Both 0.7656 1.0 0.975,1.03 5155 31730 0.865 1.0 0.973,1.03 4951 30681
594.2 Calculus of lower urinary tract genitourinary Both 0.7261 1.02 0.907,1.15 310 3068 0.6252 1.03 0.914,1.16 302 2933
594.3 Calculus of ureter genitourinary Both 0.3981 1.03 0.965,1.09 1104 11000 0.5623 1.02 0.957,1.09 1063 10622
594.8 Renal colic genitourinary Both 0.9016 0.992 0.877,1.12 286 2851 1.0 1.0 0.883,1.13 278 2773
595 Hydronephrosis genitourinary Both 0.3664 1.03 0.971,1.08 1410 14092 0.5636 1.02 0.961,1.08 1345 13586
596 Other disorders of bladder genitourinary Both 0.6561 1.01 0.969,1.05 2527 23338 0.6745 1.01 0.956,1.07 1318 13110
596.1 Bladder neck obstruction genitourinary Both 0.6592 0.975 0.87,1.09 333 3288 0.3656 0.948 0.844,1.06 319 3148
596.5 Functional disorders of bladder genitourinary Both 0.5689 1.02 0.961,1.07 1368 13608 0.6745 1.01 0.956,1.07 1318 13110
597 Other disorders of urethra and urinary tract genitourinary Both 0.2877 0.966 0.906,1.03 1041 10322 0.4508 0.939 0.798,1.11 156 1526
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.3516 0.961 0.883,1.05 608 6024 0.3981 0.964 0.885,1.05 587 5790
597.2 Urinary complications NEC genitourinary Both 0.6516 1.02 0.948,1.09 861 8600 0.9036 1.0 0.935,1.08 822 8283
597.8 Urethral hypermobility/ISD genitourinary Both 0.414 0.935 0.797,1.1 158 1578 0.4508 0.939 0.798,1.11 156 1526
598 Abnormal findings on examination of urine genitourinary Both 0.6081 1.02 0.958,1.08 1263 12596 0.7691 1.01 0.95,1.07 1157 11848
598.4 Other cells and casts in urine genitourinary Both 0.9162 0.988 0.797,1.23 91 906 0.9376 0.991 0.794,1.24 87 872
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.7889 1.01 0.951,1.07 1234 12317 0.7691 1.01 0.95,1.07 1157 11848
599 Other symptoms/disorders or the urinary system genitourinary Both 0.8395 1.0 0.98,1.03 11346 25364 0.6982 1.01 0.966,1.05 2251 19610
599.1 Urinary obstruction genitourinary Both 0.4159 0.965 0.886,1.05 580 5634 0.2685 0.951 0.871,1.04 545 5410
599.2 Retention of urine genitourinary Both 0.6998 0.993 0.961,1.03 4234 24058 0.4677 0.987 0.954,1.02 4038 23296
599.3 Dysuria genitourinary Both 0.6982 1.01 0.972,1.04 3426 23180 0.7621 1.01 0.969,1.04 3277 22442
599.4 Urinary incontinence genitourinary Both 0.4645 0.988 0.957,1.02 4566 22567 0.6637 0.993 0.961,1.03 4415 21838
599.5 Frequency of urination and polyuria genitourinary Both 1.0 1.0 0.968,1.03 4277 23742 0.9594 0.999 0.966,1.03 4092 22988
599.6 Oliguria and anuria genitourinary Both 0.7656 1.01 0.927,1.11 513 5104 0.9931 1.0 0.912,1.1 490 4901
599.7 Urethral discharge genitourinary Both 0.455 1.09 0.867,1.37 83 830 0.4276 1.1 0.869,1.39 79 795
599.8 Other symptoms involving urinary system genitourinary Both 0.7674 1.0 0.973,1.04 4366 23262 0.9078 1.0 0.969,1.04 4175 22515
599.9 Other abnormality of urination genitourinary Both 0.9226 0.998 0.956,1.04 2349 20289 0.6982 1.01 0.966,1.05 2251 19610
600 Hyperplasia of prostate genitourinary Male 0.863 0.996 0.955,1.04 3315 9437 0.5902 0.988 0.946,1.03 3131 9082
601 Inflammatory diseases of prostate genitourinary Male 0.09795 0.941 0.875,1.01 825 7745 0.1986 0.886 0.737,1.07 121 1186
601.1 Prostatitis genitourinary Male 0.3412 0.949 0.852,1.06 378 3680 0.6026 0.936 0.729,1.2 74 727
601.11 Acute prostatitis genitourinary Male 0.873 1.02 0.82,1.26 95 933 0.9772 1.0 0.805,1.25 92 912
601.12 Chronic prostatitis genitourinary Male 0.6501 0.945 0.739,1.21 76 757 0.6026 0.936 0.729,1.2 74 727
601.3 Orchitis and epididymitis genitourinary Male 0.02344 0.871 0.774,0.982 303 3008 0.013 0.858 0.76,0.968 291 2904
601.4 Balanoposthitis genitourinary Male 0.975 0.997 0.818,1.22 103 1019 0.9204 1.01 0.822,1.24 96 992
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.1633 0.879 0.734,1.05 125 1226 0.1986 0.886 0.737,1.07 121 1186
602 Other disorders of prostate genitourinary Male 0.561 1.04 0.917,1.17 277 2673 0.6081 1.03 0.91,1.17 256 2560
603 Other disorders of testis genitourinary Male 0.9397 0.996 0.891,1.11 348 3468 0.7311 0.968 0.804,1.17 121 1227
603.1 Hydrocele genitourinary Male 0.335 1.07 0.933,1.23 229 2281 0.2951 1.08 0.938,1.24 222 2191
603.2 Spermatocele genitourinary Male 0.6012 0.953 0.794,1.14 126 1258 0.7311 0.968 0.804,1.17 121 1227
604 Disorders of penis genitourinary Male 0.6966 0.982 0.898,1.07 536 5321 0.0542 0.852 0.724,1.0 163 1635
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.7311 1.03 0.863,1.23 130 1297 0.5888 1.05 0.877,1.26 125 1244
604.3 Peyronie's disease genitourinary Male 0.06637 0.862 0.736,1.01 171 1703 0.0542 0.852 0.724,1.0 163 1635
605 Erectile dysfunction [ED] genitourinary Male 0.2506 1.03 0.983,1.07 2844 10666 0.2799 1.02 0.981,1.07 2745 10287
608 Other disorders of male genital organs genitourinary Male 0.6622 0.987 0.932,1.05 1302 11530 0.8035 0.993 0.936,1.05 1247 11143
609 Male infertility and abnormal spermatozoa genitourinary Male 0.2084 0.93 0.832,1.04 335 3350 0.7161 0.964 0.792,1.17 115 1141
609.1 Infertility, male genitourinary Male 0.2512 0.926 0.811,1.06 242 2420 0.01641 0.75 0.593,0.949 78 774
609.11 Azoospermia and oligospermia genitourinary Male 0.01493 0.749 0.593,0.945 79 789 0.01641 0.75 0.593,0.949 78 774
609.2 Abnormal spermatozoa genitourinary Male 0.7568 0.97 0.8,1.18 119 1185 0.7161 0.964 0.792,1.17 115 1141
610 Benign mammary dysplasias genitourinary Female 0.6442 1.01 0.971,1.05 3089 13905 0.01884 1.08 1.01,1.15 982 9921
610.1 Cystic mastopathy genitourinary Female 0.01959 1.07 1.01,1.13 1361 12011 0.02449 1.07 1.01,1.13 1273 11738
610.4 Benign neoplasm of breast genitourinary Female 0.7129 0.992 0.95,1.04 2400 13828 0.6546 0.99 0.947,1.04 2260 13534
610.8 Other specified benign mammary dysplasias genitourinary Female 0.02421 1.08 1.01,1.15 1047 10149 0.01884 1.08 1.01,1.15 982 9921
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.01384 1.04 1.01,1.08 4952 15509 0.03819 1.04 1.0,1.09 2795 15105
611.1 Abnormal mammogram genitourinary Both 0.02924 1.04 1.0,1.08 4074 13538 0.5321 0.978 0.913,1.05 895 8899
611.11 Mammographic microcalcification genitourinary Both 0.867 0.994 0.931,1.06 962 9131 0.5321 0.978 0.913,1.05 895 8899
611.3 Lump or mass in breast genitourinary Both 0.01746 1.05 1.01,1.09 3011 15449 0.03819 1.04 1.0,1.09 2795 15105
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.5224 1.02 0.954,1.1 879 8768 0.9183 1.0 0.926,1.09 649 6557
612.1 Galactorrhea genitourinary Both 0.9397 0.993 0.821,1.2 109 1083 0.984 0.998 0.82,1.21 101 1061
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.861 1.01 0.93,1.09 672 6710 0.9183 1.0 0.926,1.09 649 6557
612.3 Congenital anomalies of breast genitourinary Both 0.1306 1.2 0.947,1.52 70 676 ,
613 Other nonmalignant breast conditions genitourinary Both 0.1545 1.03 0.99,1.07 3180 18154 0.7889 1.01 0.948,1.07 1090 11601
613.1 Inflammatory disease of breast genitourinary Both 0.6577 0.98 0.894,1.07 504 5035 0.8241 0.989 0.9,1.09 474 4898
613.5 Mastodynia genitourinary Both 0.05082 1.06 1.0,1.12 1313 12942 0.03055 1.07 1.01,1.13 1241 12598
613.7 Other signs and symptoms in breast genitourinary Both 0.7516 1.01 0.938,1.09 722 7109 0.865 0.993 0.918,1.07 677 6929
613.8 Other specified disorders of breast genitourinary Both 0.6592 0.984 0.915,1.06 800 7961 0.6339 0.982 0.911,1.06 755 7747
613.9 Breast disorder NOS genitourinary Both 0.7745 1.01 0.951,1.07 1211 11947 0.7889 1.01 0.948,1.07 1090 11601
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.8375 1.0 0.965,1.04 2990 16271 0.8933 1.01 0.855,1.2 157 1568
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.1403 0.909 0.802,1.03 267 2670 0.09354 0.896 0.788,1.02 258 2597
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.9376 0.996 0.901,1.1 404 4024 0.8279 0.984 0.851,1.14 194 1930
614.31 Acute inflammatory pelvic disease genitourinary Female 0.7228 0.958 0.755,1.21 74 720 0.7379 0.959 0.753,1.22 72 701
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.2851 1.09 0.93,1.28 167 1666 0.2698 1.1 0.932,1.29 161 1617
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.7674 0.979 0.848,1.13 198 1979 0.8279 0.984 0.851,1.14 194 1930
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.7211 0.968 0.809,1.16 129 1290 0.547 0.946 0.789,1.13 127 1268
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.5236 1.01 0.972,1.06 2546 16112 0.8933 1.01 0.855,1.2 157 1568
614.51 Cervicitis and endocervicitis genitourinary Female 0.9931 1.0 0.867,1.16 197 1970 0.9311 0.994 0.857,1.15 188 1918
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.6266 1.01 0.967,1.06 2201 15690 0.5164 1.02 0.97,1.06 2125 15219
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.6776 1.04 0.853,1.28 104 1040 0.5662 1.06 0.865,1.3 101 1009
614.54 Abscess or ulceration of vulva genitourinary Female 0.9311 1.01 0.855,1.19 164 1619 0.8933 1.01 0.855,1.2 157 1568
615 Endometriosis genitourinary Female 0.3281 1.03 0.972,1.09 1298 12230 0.2786 1.03 0.974,1.09 1258 11884
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.7834 1.01 0.954,1.06 1415 13522 0.9863 0.999 0.945,1.06 1367 13113
618 Genital prolapse genitourinary Female 0.4688 1.02 0.969,1.07 1707 14626 0.5572 1.03 0.928,1.15 368 3603
618.1 Prolapse of vaginal walls genitourinary Female 0.4375 1.02 0.965,1.09 1179 11187 0.3243 1.03 0.97,1.1 1147 10755
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.5768 1.03 0.933,1.13 444 4418 0.507 1.03 0.937,1.14 429 4258
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.9705 0.998 0.886,1.12 286 2855 0.9705 1.0 0.889,1.13 278 2725
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.5636 1.03 0.928,1.15 375 3750 0.5572 1.03 0.928,1.15 368 3603
619 Noninflammatory female genital disorders genitourinary Female 0.1337 1.03 0.992,1.06 4598 15534 0.1306 1.06 0.984,1.13 883 8833
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.455 0.978 0.923,1.04 1262 11294 0.5129 0.98 0.924,1.04 1220 10988
619.2 Disorders of uterus, NEC genitourinary Female 0.3581 1.05 0.95,1.15 444 4435 0.4645 1.04 0.939,1.15 415 4299
619.3 Noninflammatory disorders of cervix genitourinary Female 0.7638 1.02 0.915,1.13 391 3892 0.9683 0.998 0.897,1.11 376 3782
619.4 Noninflammatory disorders of vagina genitourinary Female 0.8337 1.01 0.958,1.05 1903 15019 0.8892 0.996 0.949,1.05 1828 14577
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.1132 1.06 0.987,1.13 914 9082 0.1306 1.06 0.984,1.13 883 8833
620 Dysplasia of female genital organs genitourinary Female 0.2523 1.07 0.954,1.2 325 3234 0.125 1.15 0.962,1.37 139 1384
620.1 Dysplasia of cervix genitourinary Female 0.09772 1.16 0.973,1.38 142 1420 0.125 1.15 0.962,1.37 139 1384
621 Endometrial hyperplasia genitourinary Female 0.3319 0.946 0.845,1.06 334 3335 0.4508 0.957 0.852,1.07 319 3211
622 Polyp of female genital organs genitourinary Female 0.8017 0.992 0.935,1.05 1191 11723 0.6839 0.976 0.87,1.1 328 3369
622.1 Polyp of corpus uteri genitourinary Female 0.9931 1.0 0.935,1.07 949 9362 0.9226 1.0 0.937,1.07 909 9058
622.2 Mucous polyp of cervix genitourinary Female 0.9162 0.994 0.889,1.11 348 3480 0.6839 0.976 0.87,1.1 328 3369
623 Hypertrophy of female genital organs genitourinary Female 0.3882 1.04 0.955,1.13 605 6003 0.4753 1.03 0.947,1.12 582 5815
624 Symptoms involving female genital tract genitourinary Female 0.873 0.995 0.932,1.06 1013 9695 0.02009 1.06 1.01,1.12 1515 12512
624.1 Dystrophy of female genital tract genitourinary Female 0.9705 0.997 0.855,1.16 168 1680 0.929 0.993 0.845,1.17 155 1633
624.9 stress incontinence, female genitourinary Female 0.02547 1.06 1.01,1.12 1549 12918 0.02009 1.06 1.01,1.12 1515 12512
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.2355 1.02 0.987,1.05 4618 14394 0.5741 0.981 0.919,1.05 975 9804
625.1 Dyspareunia genitourinary Female 0.5495 0.98 0.919,1.05 1011 10081 0.5741 0.981 0.919,1.05 975 9804
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.07031 1.03 0.997,1.07 4726 13065 0.263 1.05 0.965,1.14 618 5113
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.1528 1.03 0.99,1.07 3426 12112 0.4467 1.05 0.93,1.18 298 2950
626.11 Absent or infrequent menstruation genitourinary Female 0.507 0.975 0.906,1.05 802 6948 0.6026 0.98 0.909,1.06 775 6813
626.12 Excessive or frequent menstruation genitourinary Female 0.02483 1.06 1.01,1.12 1703 9843 0.03048 1.06 1.01,1.12 1649 9621
626.13 Irregular menstrual cycle genitourinary Female 0.2535 1.03 0.978,1.09 1543 10197 0.2748 1.03 0.976,1.09 1495 9962
626.14 Irregular menstrual bleeding genitourinary Female 0.06714 1.07 0.995,1.16 777 7408 0.0929 1.07 0.989,1.15 748 7255
626.15 Infertility, female, associated with anovulation genitourinary Female 0.4624 1.05 0.929,1.18 300 3000 0.4467 1.05 0.93,1.18 298 2950
626.2 Dysmenorrhea genitourinary Female 0.9772 0.999 0.938,1.06 1116 8297 0.9638 0.998 0.937,1.06 1090 8117
626.4 Premenstrual tension syndromes genitourinary Female 0.8356 1.01 0.894,1.15 275 2741 0.8128 1.02 0.895,1.15 267 2680
626.8 Infertility, female genitourinary Female 0.25 1.05 0.966,1.14 630 5218 0.263 1.05 0.965,1.14 618 5113
627 Menopausal and postmenopausal disorders genitourinary Female 0.1358 1.03 0.991,1.07 3657 12296 0.1762 0.908 0.79,1.04 210 2288
627.1 Postmenopausal bleeding genitourinary Female 0.9572 1.0 0.937,1.07 957 8768 0.7079 0.987 0.921,1.06 905 8470
627.2 Symptomatic menopause genitourinary Female 0.01429 1.06 1.01,1.1 2443 11667 0.1242 1.1 0.975,1.24 286 2832
627.21 Symptomatic artificial menopause genitourinary Female 0.5649 1.06 0.879,1.27 125 1241 0.5358 1.06 0.881,1.28 120 1211
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.07194 1.11 0.99,1.25 295 2948 0.1242 1.1 0.975,1.24 286 2832
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.413 0.969 0.898,1.05 729 7262 0.2421 0.954 0.882,1.03 681 7026
627.4 Premenopausal menorrhagia genitourinary Female 0.7047 0.977 0.868,1.1 305 3020 0.695 0.976 0.866,1.1 296 2945
627.5 Premature menopause and other ovarian failure genitourinary Female 0.1213 0.9 0.788,1.03 234 2340 0.1762 0.908 0.79,1.04 210 2288
628 Ovarian cyst genitourinary Female 0.9354 1.0 0.951,1.06 1619 11554 0.8933 1.0 0.951,1.06 1552 11263
634 Miscarriage; stillbirth pregnancy complications Female 0.4624 0.97 0.895,1.05 648 6413 0.4198 1.09 0.885,1.34 93 922
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.7178 1.03 0.893,1.18 209 2090 0.5445 1.04 0.907,1.2 203 2052
634.3 Ectopic pregnancy pregnancy complications Female 0.369 1.1 0.895,1.35 95 950 0.4198 1.09 0.885,1.34 93 922
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.1472 0.928 0.84,1.03 414 4070 0.7499 0.977 0.847,1.13 204 2030
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.07413 0.894 0.79,1.01 272 2720 0.05929 0.887 0.784,1.0 268 2676
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.875 0.989 0.858,1.14 206 2060 0.7499 0.977 0.847,1.13 204 2030
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.2979 0.963 0.896,1.03 855 6402 0.455 0.91 0.709,1.17 60 592
636.1 Threatened premature labor pregnancy complications Female 0.07656 0.899 0.799,1.01 298 2980 0.06561 0.895 0.795,1.01 295 2934
636.2 Early onset of delivery pregnancy complications Female 0.5188 0.958 0.839,1.09 233 2330 0.4093 0.946 0.828,1.08 229 2289
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.2307 1.07 0.959,1.19 356 3556 0.1832 1.08 0.966,1.2 349 3490
636.8 Cervical incompetence pregnancy complications Female 0.4581 0.91 0.709,1.17 60 600 0.455 0.91 0.709,1.17 60 592
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.8054 0.974 0.789,1.2 89 884 0.5861 0.942 0.76,1.17 84 863
638 Other high-risk pregnancy pregnancy complications Female 0.5508 0.978 0.909,1.05 818 5867 0.471 0.973 0.904,1.05 807 5761
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.8933 1.01 0.912,1.11 421 4210 0.3707 1.07 0.926,1.23 208 2110
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.3707 1.07 0.927,1.23 215 2150 0.3707 1.07 0.926,1.23 208 2110
643 Excessive vomiting in pregnancy pregnancy complications Female 0.7962 1.02 0.877,1.19 181 1810 0.8954 0.985 0.789,1.23 82 855
643.1 Hyperemesis gravidarum pregnancy complications Female 0.8091 0.974 0.784,1.21 87 870 0.8954 0.985 0.789,1.23 82 855
644 Anemia during pregnancy pregnancy complications Female 0.02265 0.819 0.69,0.972 154 1540 0.01521 0.806 0.677,0.959 150 1515
645 Late pregnancy and failed induction pregnancy complications Female 0.5188 1.04 0.922,1.17 286 2860 0.6855 1.03 0.908,1.16 283 2804
646 Other complications of pregnancy NEC pregnancy complications Female 0.2339 0.951 0.876,1.03 622 5063 0.1982 0.947 0.871,1.03 613 4977
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.8241 0.981 0.832,1.16 152 1520 0.865 0.987 0.853,1.14 180 1791
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.8318 0.984 0.851,1.14 182 1820 0.865 0.987 0.853,1.14 180 1791
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.6067 0.982 0.918,1.05 968 6387 0.5649 1.03 0.929,1.14 405 4035
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.4966 1.04 0.935,1.15 413 4130 0.5649 1.03 0.929,1.14 405 4035
650 Normal delivery pregnancy complications Female 0.2296 0.955 0.885,1.03 757 6412 0.1596 0.947 0.877,1.02 741 6283
651 Multiple gestation pregnancy complications Female 0.2118 1.14 0.928,1.4 100 1000 0.2065 1.14 0.929,1.4 99 985
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.9226 1.0 0.913,1.11 461 4586 0.8551 1.01 0.916,1.11 456 4487
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.8492 1.01 0.915,1.11 443 4189 0.859 1.01 0.914,1.11 434 4118
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.7674 1.01 0.923,1.11 482 4820 0.1199 0.879 0.747,1.03 161 1604
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.3622 1.05 0.946,1.16 402 4020 0.2864 1.06 0.953,1.18 397 3937
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.1393 0.885 0.753,1.04 163 1630 0.1199 0.879 0.747,1.03 161 1604
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.3945 0.974 0.917,1.03 1244 8117 0.8472 1.01 0.917,1.11 447 4293
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.8035 1.01 0.919,1.11 451 4371 0.8472 1.01 0.917,1.11 447 4293
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.2559 1.08 0.947,1.23 246 2460 0.01236 1.41 1.08,1.84 57 573
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.01409 1.39 1.07,1.81 59 590 0.01236 1.41 1.08,1.84 57 573
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.4227 0.942 0.814,1.09 195 1950 0.3631 0.933 0.805,1.08 188 1909
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.4943 0.968 0.883,1.06 504 4732 0.5129 0.969 0.883,1.06 494 4646
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.4808 0.964 0.872,1.07 420 4080 0.4808 0.964 0.872,1.07 414 4007
665 Obstetrical/birth trauma pregnancy complications Female 0.4064 0.968 0.898,1.04 751 6161 0.4121 0.969 0.897,1.05 734 6037
669 Complications of labor and delivery NEC pregnancy complications Female 0.5164 0.974 0.898,1.06 671 5265 0.4613 0.97 0.894,1.05 659 5168
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.9772 1.0 0.859,1.17 172 1720 0.8337 0.983 0.841,1.15 168 1678
674 Other complications of the puerperium NEC pregnancy complications Female 0.235 0.911 0.781,1.06 181 1810 0.3899 0.934 0.8,1.09 178 1778
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.4074 0.927 0.774,1.11 122 1220 0.4198 0.928 0.773,1.11 119 1206
681 Superficial cellulitis and abscess dermatologic Both 0.8954 0.998 0.969,1.03 5078 31991 0.4732 0.978 0.921,1.04 1157 11958
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.5248 1.02 0.954,1.1 862 8581 0.4365 1.03 0.958,1.11 810 8298
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.2051 0.954 0.886,1.03 781 7775 0.263 0.958 0.888,1.03 737 7519
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.6252 0.987 0.936,1.04 1533 15238 0.4498 0.979 0.927,1.03 1420 14731
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.375 0.977 0.929,1.03 1649 16359 0.2009 0.966 0.917,1.02 1532 15815
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.4742 0.979 0.925,1.04 1291 12850 0.2455 0.965 0.91,1.02 1192 12412
681.7 Cellulitis and abscess of trunk dermatologic Both 0.6223 0.985 0.93,1.04 1238 12342 0.4732 0.978 0.921,1.04 1157 11958
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.4932 0.982 0.934,1.03 1660 16466 0.881 0.986 0.814,1.19 115 1163
686.1 Carbuncle and furuncle dermatologic Both 0.01652 1.14 1.02,1.26 390 3881 0.00879 1.15 1.04,1.28 373 3775
686.2 Impetigo dermatologic Both 0.1164 1.1 0.977,1.23 310 3068 0.0743 1.11 0.989,1.25 292 2982
686.3 Pilonidal cyst dermatologic Both 0.9354 1.01 0.836,1.22 120 1200 0.8128 1.02 0.846,1.24 116 1183
686.4 Pyogenic granuloma dermatologic Both 0.9162 0.99 0.821,1.19 121 1205 0.881 0.986 0.814,1.19 115 1163
687 Symptoms affecting skin dermatologic Both 0.1718 1.02 0.992,1.05 6119 25901 0.0236 1.04 1.0,1.07 4715 24975
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.2582 1.02 0.988,1.05 5371 25824 0.4009 1.01 0.983,1.04 5042 25212
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.07278 1.03 0.997,1.06 5264 25870 0.1014 1.03 0.995,1.06 4855 25258
687.3 Changes in skin texture dermatologic Both 0.2594 1.07 0.951,1.2 294 2926 0.4529 1.05 0.927,1.18 272 2844
687.4 Disturbance of skin sensation dermatologic Both 0.009441 1.04 1.01,1.07 4942 25586 0.0236 1.04 1.0,1.07 4715 24975
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.9616 1.0 0.975,1.03 7192 31086 0.811 0.997 0.971,1.02 6759 30211
690 Erythematosquamous dermatosis dermatologic Both 0.7161 1.01 0.973,1.04 3810 26256 0.9683 1.0 0.966,1.04 3611 25337
690.1 Seborrheic dermatitis dermatologic Both 0.7551 1.01 0.972,1.04 3802 26218 0.9683 1.0 0.966,1.04 3611 25337
691 Congenital anomalies of skin dermatologic Both 0.2218 0.938 0.847,1.04 411 4110 0.2265 0.936 0.842,1.04 381 3969
694 Dyschromia and Vitiligo dermatologic Both 0.9183 1.0 0.947,1.06 1286 12819 0.6761 1.06 0.808,1.39 61 665
694.1 Vitiligo dermatologic Both 0.2223 0.879 0.714,1.08 94 931 0.2275 0.878 0.711,1.08 91 900
694.2 Other dyschromia dermatologic Both 0.7798 1.01 0.949,1.07 1146 11421 0.9397 1.0 0.942,1.07 1083 11041
694.3 Vascular disorders of skin dermatologic Both 0.5395 1.08 0.838,1.4 69 686 0.6761 1.06 0.808,1.39 61 665
695 Erythematous conditions dermatologic Both 0.6966 1.01 0.971,1.05 3180 24642 0.03945 0.906 0.826,0.995 474 4930
695.2 Bullous dermatoses dermatologic Both 0.6427 1.06 0.837,1.33 68 658 0.5902 1.07 0.842,1.35 66 639
695.3 Rosacea dermatologic Both 0.2104 1.04 0.98,1.09 1405 14019 0.2208 1.04 0.979,1.1 1340 13536
695.4 Lupus (localized and systemic) dermatologic Both 0.4864 1.03 0.946,1.12 556 5556 0.4699 1.03 0.944,1.13 501 5128
695.41 Cutaneous lupus erythematosus dermatologic Both 0.7603 1.02 0.885,1.18 196 1955 0.9817 0.998 0.86,1.16 186 1897
695.42 Systemic lupus erythematosus dermatologic Both 0.4732 1.03 0.945,1.13 530 5287 0.4699 1.03 0.944,1.13 501 5128
695.7 Prurigo and Lichen dermatologic Both 0.7112 0.981 0.888,1.08 429 4275 0.6442 0.976 0.88,1.08 401 4115
695.8 Other specified erythematous conditions dermatologic Both 0.6012 1.02 0.941,1.11 613 6111 0.4677 1.03 0.948,1.12 577 5895
695.9 Unspecified erythematous condition dermatologic Both 0.03873 0.91 0.831,0.995 513 5102 0.03945 0.906 0.826,0.995 474 4930
696 Psoriasis and related disorders dermatologic Both 0.5572 1.02 0.957,1.09 1080 10781 0.1271 1.11 0.97,1.28 218 2187
696.3 Pityriasis dermatologic Both 0.6383 0.941 0.732,1.21 64 640 0.4786 0.91 0.7,1.18 60 624
696.4 Psoriasis dermatologic Both 0.492 1.02 0.959,1.09 1014 10115 0.1271 1.11 0.97,1.28 218 2187
696.41 Psoriasis vulgaris dermatologic Both 0.4887 1.02 0.957,1.1 918 9161 0.526 1.02 0.954,1.1 881 8849
696.42 Psoriatic arthropathy dermatologic Both 0.2 1.09 0.954,1.25 225 2250 0.1271 1.11 0.97,1.28 218 2187
697 Sarcoidosis dermatologic Both 0.7396 0.979 0.863,1.11 265 2650 0.7211 0.976 0.852,1.12 228 2566
698 Pruritus and related conditions dermatologic Both 0.2183 1.03 0.982,1.08 1686 16680 0.4046 1.02 0.971,1.08 1591 16096
700 Corns and callosities dermatologic Both 0.13 0.944 0.877,1.02 764 7615 0.0597 0.929 0.861,1.0 723 7325
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.8851 0.998 0.97,1.03 5838 31889 0.2415 0.935 0.834,1.05 309 3157
701.1 Keratoderma, acquired dermatologic Both 0.5 0.964 0.868,1.07 389 3845 0.4036 0.954 0.855,1.06 359 3700
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.08147 0.957 0.91,1.01 1705 16953 0.0542 0.951 0.903,1.0 1604 16430
701.3 Circumscribed scleroderma dermatologic Both 0.7482 1.02 0.922,1.12 434 4334 0.8892 0.993 0.898,1.1 408 4217
701.4 Keloid scar dermatologic Both 0.03041 1.11 1.01,1.23 454 4503 0.06561 1.1 0.994,1.21 430 4375
701.5 Abnormal granulation tissue dermatologic Both 0.3802 0.952 0.852,1.06 328 3260 0.2415 0.935 0.834,1.05 309 3157
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.7194 0.995 0.965,1.02 5351 24908 0.6209 1.07 0.818,1.4 58 606
702.1 Actinic keratosis dermatologic Both 0.9016 1.0 0.966,1.04 3236 22206 0.8974 1.0 0.965,1.04 3038 21365
702.2 Seborrheic keratosis dermatologic Both 0.514 1.01 0.978,1.04 4151 26248 0.7413 1.01 0.972,1.04 3928 25318
702.4 Degenerative skin disorders dermatologic Both 0.9795 1.0 0.775,1.3 63 624 0.6209 1.07 0.818,1.4 58 606
703 Diseases of nail, NOS dermatologic Both 0.07482 1.06 0.994,1.13 1033 10222 0.9705 0.998 0.916,1.09 549 5578
703.1 Ingrowing nail dermatologic Both 0.9099 1.0 0.924,1.09 580 5773 0.9705 0.998 0.916,1.09 549 5578
704 Diseases of hair and hair follicles dermatologic Both 0.1493 1.03 0.989,1.08 2321 22718 0.6039 1.02 0.958,1.08 1220 12385
704.1 Alopecia dermatologic Both 0.1002 1.05 0.99,1.12 1074 10601 0.005358 1.49 1.13,1.97 53 557
704.11 Alopecia Areata dermatologic Both 0.02884 1.34 1.03,1.75 58 580 0.005358 1.49 1.13,1.97 53 557
704.2 Hirsutism dermatologic Both 0.06471 1.14 0.992,1.3 227 2263 0.09908 1.12 0.979,1.29 220 2207
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.5636 1.02 0.96,1.08 1286 12791 0.6039 1.02 0.958,1.08 1220 12385
705 Disorders of sweat glands dermatologic Both 0.6295 0.976 0.885,1.08 439 4376 0.4467 1.03 0.956,1.11 781 8165
705.1 Dyshidrosis dermatologic Both 0.1297 0.864 0.716,1.04 114 1131 0.1164 0.857 0.706,1.04 109 1084
705.3 Hidradenitis dermatologic Both 0.5754 1.04 0.896,1.22 183 1815 0.5728 1.05 0.895,1.22 180 1769
705.8 Hyperhidrosis dermatologic Both 0.2649 1.04 0.97,1.12 846 8429 0.4467 1.03 0.956,1.11 781 8165
706 Diseases of sebaceous glands dermatologic Both 0.3221 1.02 0.985,1.05 4454 32859 0.2735 0.965 0.906,1.03 1050 10712
706.1 Acne dermatologic Both 0.3273 1.02 0.977,1.07 1931 17499 0.4188 1.02 0.972,1.07 1855 17033
706.2 Sebaceous cyst dermatologic Both 0.3069 1.02 0.979,1.07 2150 21106 0.3656 1.02 0.976,1.07 2048 20393
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.2466 0.964 0.907,1.03 1124 11122 0.2735 0.965 0.906,1.03 1050 10712
707 Chronic ulcer of skin dermatologic Both 0.865 1.0 0.961,1.05 2193 21811 0.1528 1.04 0.984,1.11 1256 12896
707.1 Decubitus ulcer dermatologic Both 0.8414 1.01 0.927,1.1 600 5984 0.8318 1.01 0.926,1.1 567 5760
707.2 Chronic ulcer of leg or foot dermatologic Both 0.8017 1.01 0.936,1.09 721 7166 0.9977 1.0 0.924,1.08 680 6904
707.3 Chronic ulcer of unspecified site dermatologic Both 0.1247 1.04 0.988,1.11 1339 13370 0.1528 1.04 0.984,1.11 1256 12896
709 Diffuse diseases of connective tissue dermatologic Both 0.7962 1.01 0.948,1.07 1086 10825 0.8551 0.992 0.915,1.08 624 6355
709.2 Sicca syndrome dermatologic Both 0.6067 1.03 0.925,1.14 365 3650 0.6166 1.03 0.922,1.15 348 3518
709.3 Systemic sclerosis dermatologic Both 0.3802 0.933 0.799,1.09 184 1840 0.4365 0.939 0.801,1.1 179 1798
709.5 Dermatomyositis dermatologic Both 0.7727 1.04 0.813,1.32 70 700 0.7261 1.05 0.814,1.34 66 671
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.929 1.01 0.798,1.28 78 780 0.9886 0.998 0.787,1.27 77 767
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.955 1.0 0.926,1.09 659 6563 0.8551 0.992 0.915,1.08 624 6355
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.04102 1.03 1.0,1.06 5120 27320 0.9036 0.985 0.764,1.27 62 603
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.798 1.03 0.807,1.32 64 626 0.9036 0.985 0.764,1.27 62 603
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.241 1.04 0.974,1.11 954 9524 0.3873 1.03 0.961,1.11 824 8326
710.1 Osteomyelitis musculoskeletal Both 0.2228 1.04 0.975,1.12 914 9127 0.3873 1.03 0.961,1.11 824 8326
710.11 Acute osteomyelitis musculoskeletal Both 0.08072 1.09 0.989,1.21 425 4234 0.1297 1.08 0.977,1.2 401 4056
710.12 Chronic osteomyelitis musculoskeletal Both 0.5236 0.966 0.868,1.07 378 3758 0.4634 0.96 0.86,1.07 356 3602
710.19 Unspecified osteomyelitis musculoskeletal Both 0.1656 1.05 0.98,1.13 867 8656 0.3873 1.03 0.961,1.11 824 8326
711 Arthropathy associated with infections musculoskeletal Both 0.7031 1.02 0.911,1.15 314 3124 0.52 0.955 0.831,1.1 212 2140
711.1 Pyogenic arthritis musculoskeletal Both 0.4624 0.95 0.829,1.09 223 2206 0.52 0.955 0.831,1.1 212 2140
712 Infective connective tissue disorders musculoskeletal Both 0.4989 1.06 0.892,1.26 136 1360 0.4764 1.07 0.892,1.28 130 1303
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.9462 0.995 0.868,1.14 222 2214 0.631 0.955 0.79,1.15 113 1136
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.787 0.975 0.809,1.17 118 1180 0.631 0.955 0.79,1.15 113 1136
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.002104 1.08 1.03,1.14 1649 14662 0.01596 1.07 1.01,1.14 1288 11877
714.1 Rheumatoid arthritis musculoskeletal Both 0.02438 1.07 1.01,1.13 1342 12332 0.01596 1.07 1.01,1.14 1288 11877
715 Other inflammatory spondylopathies musculoskeletal Both 0.05572 1.07 0.998,1.14 979 9761 0.06699 1.15 0.99,1.34 173 1699
715.1 Sacroiliitis NEC musculoskeletal Both 0.342 1.07 0.93,1.23 212 2120 0.2312 1.09 0.945,1.26 202 2046
715.2 Ankylosing spondylitis musculoskeletal Both 0.1026 1.13 0.975,1.32 177 1760 0.06699 1.15 0.99,1.34 173 1699
716 Other arthropathies musculoskeletal Both 0.006152 1.03 1.01,1.06 10893 26011 0.009311 1.03 1.01,1.06 10408 25183
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.2636 1.1 0.932,1.29 155 1540 0.2265 1.11 0.938,1.31 147 1484
716.2 Unspecified monoarthritis musculoskeletal Both 0.2366 1.12 0.93,1.34 116 1156 0.2455 1.12 0.927,1.35 112 1118
716.9 Arthropathy NOS musculoskeletal Both 0.005848 1.03 1.01,1.06 10831 26002 0.009311 1.03 1.01,1.06 10408 25183
717 Polymyalgia Rheumatica musculoskeletal Both 0.2046 1.09 0.953,1.25 210 2061 0.2404 1.09 0.944,1.26 196 1964
720 Spinal stenosis musculoskeletal Both 0.0912 1.03 0.995,1.07 3298 24117 0.04786 1.04 1.0,1.09 2313 19688
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.05929 1.04 0.998,1.09 2415 20454 0.04786 1.04 1.0,1.09 2313 19688
721 Spondylosis and allied disorders musculoskeletal Both 0.005957 1.05 1.01,1.08 4494 27007 0.4742 0.948 0.819,1.1 204 2026
721.1 Spondylosis without myelopathy musculoskeletal Both 0.004325 1.05 1.02,1.08 4206 26584 0.006776 1.05 1.01,1.08 4021 25683
721.2 Spondylosis with myelopathy musculoskeletal Both 0.7063 1.01 0.941,1.09 740 7398 0.507 1.03 0.951,1.11 717 7111
721.8 Other allied disorders of spine musculoskeletal Both 0.309 0.928 0.804,1.07 212 2099 0.4742 0.948 0.819,1.1 204 2026
722 Intervertebral disc disorders musculoskeletal Both 0.002812 1.05 1.02,1.08 5242 28702 0.01945 1.07 1.01,1.12 1512 15148
722.1 Displacement of intervertebral disc musculoskeletal Both 2.576E-4 1.07 1.03,1.11 3038 26827 3.698E-4 1.07 1.03,1.11 2900 25943
722.3 Schmorl's nodes musculoskeletal Both 0.8851 1.01 0.839,1.23 115 1140 0.5358 1.06 0.873,1.3 104 1103
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.004875 1.05 1.02,1.09 3338 26140 0.007925 1.05 1.01,1.09 3192 25248
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.597 1.03 0.933,1.13 464 4634 0.4732 1.04 0.94,1.14 449 4457
722.8 Postlaminectomy syndrome musculoskeletal Both 0.2518 1.07 0.954,1.19 336 3360 0.1683 1.08 0.967,1.21 327 3226
722.9 Other and unspecified disc disorder musculoskeletal Both 0.02904 1.06 1.01,1.12 1569 15676 0.01945 1.07 1.01,1.12 1512 15148
723 Other disorders of cervical region musculoskeletal Both 0.5458 1.02 0.95,1.1 761 7610 0.8414 1.02 0.871,1.19 176 1814
723.1 Torticollis musculoskeletal Both 0.8511 1.01 0.873,1.18 187 1870 0.8414 1.02 0.871,1.19 176 1814
724 Other and unspecified disorders of back musculoskeletal Both 0.02291 1.04 1.01,1.08 3338 26730 0.1321 1.05 0.986,1.11 1189 11968
724.1 Disorders of sacrum musculoskeletal Both 0.2799 1.03 0.979,1.08 1804 17663 0.2851 1.03 0.978,1.08 1738 17070
724.2 Disorders of coccyx musculoskeletal Both 0.02649 1.14 1.01,1.27 331 3290 0.0507 1.12 1.0,1.26 322 3184
724.8 Other symptoms referable to back musculoskeletal Both 0.2173 1.05 0.973,1.13 753 7499 0.1552 1.06 0.979,1.14 731 7219
724.9 Other unspecified back disorders musculoskeletal Both 0.1205 1.05 0.988,1.11 1246 12418 0.1321 1.05 0.986,1.11 1189 11968
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.04477 1.03 1.0,1.05 7682 25455 0.008337 0.91 0.848,0.976 864 8547
726.1 Enthesopathy musculoskeletal Both 0.1199 1.02 0.994,1.05 5795 25454 0.166 1.02 0.991,1.05 5600 24660
726.2 Synoviopathy musculoskeletal Both 0.4592 0.973 0.904,1.05 774 7723 0.5395 0.977 0.907,1.05 757 7451
726.3 Bursitis musculoskeletal Both 0.4256 1.02 0.967,1.08 1339 13090 0.561 1.02 0.961,1.08 1293 12635
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.02023 0.921 0.86,0.987 889 8846 0.008337 0.91 0.848,0.976 864 8547
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.007362 1.04 1.01,1.07 5811 25457 0.3006 0.906 0.751,1.09 113 1095
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.06152 1.04 0.998,1.09 2342 20541 0.08299 1.04 0.995,1.09 2263 19891
727.2 Bursitis disorders musculoskeletal Both 0.1803 1.08 0.966,1.2 341 3381 0.3556 1.05 0.942,1.18 326 3267
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.07638 1.06 0.994,1.12 1109 11034 0.1033 1.05 0.99,1.12 1072 10685
727.5 Rupture of synovium musculoskeletal Both 0.6427 1.03 0.923,1.14 376 3718 0.5248 1.04 0.93,1.15 360 3573
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.537 1.01 0.968,1.06 1927 18092 0.6152 1.01 0.965,1.06 1860 17409
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.004853 1.14 1.04,1.24 520 5187 0.00811 1.13 1.03,1.24 499 5032
727.8 Plica syndrome musculoskeletal Both 0.3357 0.913 0.758,1.1 115 1117 0.3006 0.906 0.751,1.09 113 1095
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.3864 1.02 0.98,1.05 3433 24951 0.3864 1.05 0.935,1.19 301 2980
728.1 Muscular calcification and ossification musculoskeletal Both 0.06761 0.795 0.622,1.02 69 682 0.04426 0.77 0.597,0.993 64 658
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.1259 1.11 0.971,1.27 230 2298 0.1507 1.11 0.964,1.27 226 2232
728.7 Fasciitis musculoskeletal Both 0.912 1.0 0.958,1.05 2056 19042 0.3864 1.05 0.935,1.19 301 2980
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.3388 1.06 0.941,1.19 310 3095 0.3864 1.05 0.935,1.19 301 2980
729 Other disorders of soft tissues musculoskeletal Both 0.07015 1.04 0.997,1.08 2618 22751 0.1816 0.868 0.705,1.07 99 971
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.04406 1.31 1.01,1.7 63 630 0.01995 1.38 1.05,1.8 62 604
729.3 Panniculitis musculoskeletal Both 0.1652 0.864 0.703,1.06 100 1000 0.1816 0.868 0.705,1.07 99 971
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.04977 1.34 1.0,1.8 53 530 ,
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.2924 0.912 0.769,1.08 145 1441 0.4624 0.936 0.786,1.12 137 1377
732 Osteochondropathies musculoskeletal Both 0.4875 0.96 0.854,1.08 289 2882 0.9863 0.998 0.779,1.28 69 695
732.1 Juvenile osteochondrosis musculoskeletal Both 0.1799 0.897 0.765,1.05 157 1570 0.2911 0.915 0.777,1.08 146 1529
732.7 Osteochondritis dissecans musculoskeletal Both 0.9817 0.997 0.78,1.27 71 710 0.9863 0.998 0.779,1.28 69 695
733 Other disorders of bone and cartilage musculoskeletal Both 0.7129 0.993 0.958,1.03 3481 21966 0.3459 0.894 0.709,1.13 80 773
733.2 Cyst of bone musculoskeletal Both 0.4831 0.944 0.803,1.11 162 1613 0.3357 0.923 0.784,1.09 159 1553
733.4 Aseptic necrosis of bone musculoskeletal Both 0.4256 1.04 0.941,1.15 405 4042 0.456 1.04 0.936,1.16 373 3885
733.6 Costochondritis musculoskeletal Both 0.01074 1.17 1.04,1.32 275 2742 0.00415 1.2 1.06,1.36 268 2663
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.8851 1.01 0.931,1.09 701 7003 0.8414 1.01 0.932,1.09 675 6797
733.9 Chondromalacia musculoskeletal Both 0.3656 0.899 0.713,1.13 80 800 0.3459 0.894 0.709,1.13 80 773
735 Acquired foot deformities musculoskeletal Both 0.4285 0.983 0.943,1.03 2431 23304 0.1901 0.957 0.897,1.02 1009 9919
735.1 Flat foot musculoskeletal Both 0.9594 0.998 0.905,1.1 437 4355 0.7362 0.983 0.89,1.09 421 4181
735.2 Acquired toe deformities musculoskeletal Both 0.3192 0.965 0.9,1.03 869 8616 0.7447 1.02 0.903,1.15 284 2860
735.21 Hammer toe (acquired) musculoskeletal Both 0.2786 0.951 0.867,1.04 509 5041 0.3459 0.956 0.87,1.05 488 4821
735.23 Hallux rigidus musculoskeletal Both 0.8892 1.01 0.895,1.14 299 2975 0.7447 1.02 0.903,1.15 284 2860
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.1552 0.955 0.895,1.02 1039 10308 0.1901 0.957 0.897,1.02 1009 9919
736 Other acquired deformities of limbs musculoskeletal Both 0.9419 0.998 0.953,1.05 1997 19771 0.4875 1.05 0.921,1.19 249 2464
736.1 Acquired deformities of forearm musculoskeletal Both 0.8166 0.975 0.785,1.21 90 892 0.984 0.998 0.799,1.25 84 855
736.2 Acquired deformities of finger musculoskeletal Both 0.07603 1.16 0.985,1.36 169 1684 0.06223 1.17 0.992,1.38 163 1628
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.7211 1.02 0.897,1.17 239 2382 0.6776 1.03 0.9,1.18 238 2284
736.5 Acquired deformities of knee musculoskeletal Both 0.929 1.01 0.866,1.17 184 1834 0.7656 1.02 0.879,1.19 182 1754
736.6 Unequal leg length (acquired) musculoskeletal Both 0.5035 1.04 0.92,1.19 256 2555 0.4875 1.05 0.921,1.19 249 2464
737 Curvature of spine musculoskeletal Both 0.00263 1.09 1.03,1.16 1268 12573 0.02432 1.08 1.01,1.15 959 9425
737.1 Kyphosis (acquired) musculoskeletal Both 0.008913 1.15 1.04,1.28 383 3819 0.004385 1.17 1.05,1.3 365 3675
737.2 Lordosis (acquired) musculoskeletal Both 0.9506 1.01 0.786,1.29 65 650 0.9183 1.01 0.79,1.3 65 621
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.02198 1.08 1.01,1.15 987 9782 0.02432 1.08 1.01,1.15 959 9425
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.4656 1.02 0.971,1.07 1968 19555 0.7621 1.01 0.942,1.09 834 8252
738.4 Acquired spondylolisthesis musculoskeletal Both 0.7727 1.01 0.943,1.08 863 8617 0.7621 1.01 0.942,1.09 834 8252
739 Contracture of joint musculoskeletal Both 0.7621 0.986 0.9,1.08 522 5203 0.6761 0.98 0.893,1.08 498 5043
740 Osteoarthrosis musculoskeletal Both 0.01462 1.03 1.01,1.05 13133 25195 0.02193 1.03 1.0,1.05 12138 24295
740.1 Osteoarthritis; localized musculoskeletal Both 0.1714 1.02 0.991,1.05 5329 22764 0.9795 1.0 0.914,1.1 505 4961
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.3206 1.02 0.984,1.05 4543 21500 0.4246 1.01 0.98,1.05 4384 20755
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.9705 0.998 0.912,1.09 514 5125 0.9795 1.0 0.914,1.1 505 4961
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.08395 1.05 0.993,1.12 1266 9917 0.1153 1.05 0.988,1.11 1227 9508
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.3289 1.06 0.943,1.19 303 2974 0.375 1.06 0.936,1.19 287 2854
740.9 Osteoarthrosis NOS musculoskeletal Both 0.01986 1.03 1.0,1.05 12648 25075 0.02193 1.03 1.0,1.05 12138 24295
741 Symptoms and disorders of the joints musculoskeletal Both 0.2218 1.02 0.99,1.04 6764 29838 0.9908 1.0 0.752,1.33 51 499
741.1 Ankylosis of joint musculoskeletal Both 0.6067 1.04 0.901,1.2 209 2088 0.6081 1.04 0.9,1.2 206 2019
741.2 Stiffness of joint musculoskeletal Both 0.8185 0.992 0.93,1.06 995 9908 0.7834 0.991 0.927,1.06 956 9559
741.3 Difficulty in walking musculoskeletal Both 0.6209 1.01 0.965,1.06 1854 17778 0.6295 1.01 0.964,1.06 1762 17092
741.4 Joint effusions musculoskeletal Both 0.7311 1.01 0.962,1.06 1930 19185 0.7211 1.01 0.962,1.06 1859 18548
741.5 Hemarthrosis musculoskeletal Both 0.7798 1.04 0.809,1.33 64 640 0.9311 1.01 0.783,1.31 60 613
741.6 Villonodular synovitis musculoskeletal Both 0.9638 0.994 0.752,1.31 53 522 0.9908 1.0 0.752,1.33 51 499
742 Derangement of joint, non-traumatic musculoskeletal Both 0.9078 1.0 0.967,1.04 3462 27650 0.9931 1.0 0.963,1.04 3106 26017
742.1 Loose body in joint musculoskeletal Both 0.8831 0.987 0.824,1.18 131 1295 0.7962 0.976 0.812,1.17 126 1245
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.2094 0.918 0.804,1.05 243 2414 0.1959 0.915 0.8,1.05 239 2339
742.8 Articular cartilage disorder musculoskeletal Both 0.2547 0.918 0.792,1.06 191 1896 0.2495 0.916 0.79,1.06 188 1834
742.9 Other derangement of joint musculoskeletal Both 0.955 1.0 0.965,1.04 3212 26883 0.9931 1.0 0.963,1.04 3106 26017
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.1143 1.02 0.995,1.05 7571 30458 0.1377 1.02 0.993,1.05 5451 28584
743.1 Osteoporosis musculoskeletal Both 0.8166 1.0 0.965,1.05 2982 15823 0.8185 0.984 0.858,1.13 218 2205
743.11 Osteoporosis NOS musculoskeletal Both 0.8356 1.0 0.964,1.05 2931 15630 0.7079 1.01 0.967,1.05 2777 15099
743.12 Senile osteoporosis musculoskeletal Both 0.4864 0.967 0.881,1.06 481 4333 0.5662 0.972 0.884,1.07 457 4170
743.13 Other specified osteoporosis musculoskeletal Both 0.826 0.985 0.862,1.13 231 2290 0.8185 0.984 0.858,1.13 218 2205
743.2 Pathologic fracture musculoskeletal Both 0.3289 1.04 0.966,1.11 872 8504 0.4753 1.07 0.882,1.31 104 1100
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.3656 1.05 0.946,1.16 385 3799 0.5047 1.04 0.931,1.16 355 3663
743.22 Pathologic fracture of femur musculoskeletal Both 0.8933 0.987 0.818,1.19 116 1143 0.4753 1.07 0.882,1.31 104 1100
743.4 Stress fracture musculoskeletal Both 0.4864 0.959 0.851,1.08 291 2882 0.5058 0.959 0.849,1.08 276 2806
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.1542 1.02 0.992,1.05 5795 29464 0.1377 1.02 0.993,1.05 5451 28584
745 Pain in joint musculoskeletal Both 0.02404 1.02 1.0,1.04 15755 22596 0.02655 1.02 1.0,1.05 15179 21864
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.157 1.04 0.987,1.09 1811 18049 0.04227 1.12 1.0,1.24 380 3881
747.1 Cardiac congenital anomalies congenital anomalies Both 0.7482 1.01 0.956,1.06 1446 14417 0.6792 1.02 0.915,1.15 323 3275
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.9772 0.999 0.913,1.09 519 5181 0.9099 1.01 0.917,1.1 502 4993
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.9441 0.997 0.919,1.08 632 6299 0.7925 0.989 0.909,1.08 599 6053
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.6353 1.03 0.921,1.14 342 3387 0.6792 1.02 0.915,1.15 323 3275
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.0507 1.11 1.0,1.23 402 4014 0.04227 1.12 1.0,1.24 380 3881
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.1841 1.15 0.936,1.41 93 930 0.2203 1.14 0.923,1.42 89 905
749 Congenital anomalies of face and neck congenital anomalies Both 0.8851 1.01 0.916,1.11 455 4540 0.2028 1.15 0.929,1.42 87 872
749.1 Cleft palate congenital anomalies Both 0.859 0.979 0.774,1.24 81 791 0.8433 0.977 0.771,1.24 80 778
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.2742 1.12 0.912,1.38 90 897 0.2028 1.15 0.929,1.42 87 872
750 Digestive congenital anomalies congenital anomalies Both 0.5433 1.02 0.949,1.1 739 7382 0.3041 0.921 0.787,1.08 172 1741
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.278 1.07 0.95,1.2 307 3069 0.6699 1.06 0.811,1.39 57 534
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.02234 1.27 1.04,1.57 96 944 0.02673 1.27 1.03,1.57 92 902
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.4603 0.915 0.724,1.16 77 767 0.4539 0.914 0.723,1.16 77 750
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.5848 1.05 0.877,1.26 121 1210 0.5598 1.06 0.879,1.27 118 1151
750.15 Congenital anomalies of stomach congenital anomalies Both 0.673 1.06 0.81,1.39 57 567 0.6699 1.06 0.811,1.39 57 534
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.9441 0.997 0.904,1.1 438 4363 0.3041 0.921 0.787,1.08 172 1741
750.21 Congenital anomalies of intestine congenital anomalies Both 0.5152 1.04 0.919,1.18 262 2613 0.5572 1.04 0.913,1.18 251 2514
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.5129 0.95 0.816,1.11 180 1790 0.3041 0.921 0.787,1.08 172 1741
751 Genitourinary congenital anomalies congenital anomalies Both 0.2965 1.03 0.977,1.08 1682 16764 0.3758 0.928 0.787,1.09 149 1503
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.2735 1.05 0.961,1.15 491 4897 0.4111 0.928 0.776,1.11 127 1246
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.06383 1.11 0.994,1.25 328 3280 0.1435 1.09 0.971,1.22 317 3195
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.2858 0.909 0.762,1.08 132 1301 0.4111 0.928 0.776,1.11 127 1246
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.2553 1.04 0.975,1.1 1139 11355 0.4305 1.05 0.924,1.2 243 2423
751.21 Cystic kidney disease congenital anomalies Both 0.2099 1.05 0.974,1.13 799 7929 0.3076 1.04 0.965,1.12 766 7631
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.3048 1.07 0.94,1.22 251 2506 0.4305 1.05 0.924,1.2 243 2423
751.3 Obstructive genitourinary defect congenital anomalies Both 0.5082 0.947 0.807,1.11 157 1560 0.3758 0.928 0.787,1.09 149 1503
752 Nervous system congenital anomalies congenital anomalies Both 0.9162 1.0 0.938,1.07 908 9073 0.7328 0.974 0.839,1.13 193 1939
752.1 Neural tube defects congenital anomalies Both 0.542 0.977 0.906,1.05 728 7277 0.5998 0.955 0.804,1.13 139 1401
752.11 Spina bifida congenital anomalies Both 0.5559 0.95 0.802,1.13 144 1440 0.5998 0.955 0.804,1.13 139 1401
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.7568 0.977 0.844,1.13 201 2010 0.7328 0.974 0.839,1.13 193 1939
753 Congenital anomalies of the eye congenital anomalies Both 0.4634 1.07 0.9,1.26 146 1451 0.4406 1.07 0.901,1.27 143 1400
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.3459 0.97 0.909,1.03 1006 10049 0.1489 0.932 0.848,1.03 453 4477
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.8954 1.01 0.836,1.23 116 1155 0.7568 1.03 0.848,1.25 112 1110
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.177 0.938 0.854,1.03 470 4675 0.1489 0.932 0.848,1.03 453 4477
755 Congenital anomalies of limbs congenital anomalies Both 0.02051 0.906 0.833,0.985 625 6237 0.929 0.992 0.836,1.18 147 1475
755.1 Congenital deformities of feet congenital anomalies Both 0.005212 0.845 0.751,0.951 315 3138 0.005284 0.844 0.749,0.951 310 3030
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.5888 0.93 0.716,1.21 58 567 0.5662 0.922 0.7,1.22 53 551
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.07925 0.889 0.78,1.01 258 2580 0.929 0.992 0.836,1.18 147 1475
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.873 0.986 0.833,1.17 152 1520 0.929 0.992 0.836,1.18 147 1475
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.4775 0.977 0.916,1.04 1021 10203 0.2636 0.956 0.884,1.03 706 7154
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.07586 1.28 0.975,1.67 55 527 0.04667 1.33 1.0,1.75 53 512
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.4498 0.903 0.694,1.18 56 524 0.4159 0.896 0.687,1.17 56 514
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.3767 1.06 0.931,1.21 246 2459 0.3289 1.07 0.937,1.22 243 2374
756.5 Congenital osteodystrophies congenital anomalies Both 0.2239 0.954 0.884,1.03 743 7419 0.2636 0.956 0.884,1.03 706 7154
757 Congenital anomalies of the integument congenital anomalies Both 0.09311 0.901 0.798,1.02 283 2820 0.1253 0.907 0.801,1.03 272 2719
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.01875 0.799 0.662,0.963 134 1334 0.7145 0.957 0.757,1.21 86 894
758.1 Chromosomal anomalies congenital anomalies Both 0.6934 0.955 0.761,1.2 91 910 0.7145 0.957 0.757,1.21 86 894
759 Other and unspecified congenital anomalies congenital anomalies Both 0.955 1.0 0.914,1.1 498 4964 0.4955 1.1 0.836,1.45 54 553
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.271 1.16 0.89,1.52 57 567 0.4955 1.1 0.836,1.45 54 553
760 Back pain symptoms Both 0.1986 1.01 0.993,1.04 12687 25663 0.2173 1.01 0.992,1.04 12191 24851
761 Cervicalgia symptoms Both 0.0863 1.03 0.996,1.06 5134 32829 0.06427 1.03 0.998,1.06 4922 31742
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.00263 1.06 1.02,1.1 2927 27356 0.003733 1.06 1.02,1.1 2797 26372
764 Sciatica symptoms Both 0.00859 1.06 1.01,1.1 2623 25291 0.02138 1.05 1.01,1.09 2512 24376
765 Cervical radiculitis symptoms Both 0.1426 1.04 0.986,1.1 1401 13966 0.157 1.04 0.985,1.1 1357 13464
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.07079 1.03 0.997,1.07 4004 31031 0.06855 1.03 0.998,1.07 3834 29998
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.3581 0.899 0.716,1.13 85 835 0.4395 0.912 0.721,1.15 80 815
769 Nonallopathic lesions NEC symptoms Both 0.9772 1.0 0.936,1.07 923 9183 0.869 1.01 0.938,1.08 873 8860
770 Myalgia and myositis unspecified symptoms Both 0.16 1.02 0.991,1.06 4324 27592 0.1265 1.03 0.993,1.06 4141 26686
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.002014 1.06 1.02,1.09 3638 29710 0.798 0.99 0.918,1.07 732 7606
771.1 Swelling of limb symptoms Both 0.3524 1.02 0.984,1.05 4511 29862 0.4266 1.01 0.981,1.05 4214 28997
771.2 Cramp of limb symptoms Both 0.5623 0.979 0.91,1.05 791 7856 0.798 0.99 0.918,1.07 732 7606
772 Symptoms of the muscles symptoms Both 0.7889 1.01 0.956,1.06 1549 15345 0.9795 1.0 0.898,1.12 350 3579
772.1 Muscular wasting and disuse atrophy symptoms Both 0.4786 1.04 0.929,1.17 320 3187 0.413 1.05 0.934,1.18 313 3091
772.2 Spasm of muscle symptoms Both 0.5957 1.01 0.965,1.06 1780 17782 0.5943 1.01 0.964,1.07 1709 17227
772.3 Muscle weakness symptoms Both 0.2748 1.02 0.981,1.07 2339 22770 0.2685 1.02 0.981,1.07 2204 21943
772.4 Rhabdomyolysis symptoms Both 0.227 0.891 0.738,1.07 117 1170 0.2523 0.893 0.736,1.08 111 1131
772.6 Facial weakness symptoms Both 0.7907 0.986 0.888,1.09 377 3746 0.9795 1.0 0.898,1.12 350 3579
773 Pain in limb symptoms Both 0.3251 1.01 0.989,1.03 11393 26958 0.5916 1.01 0.984,1.03 10920 26123
780 Hypothermia/Chills symptoms Both 0.7096 0.978 0.87,1.1 307 3069 0.6295 0.97 0.858,1.1 277 2954
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.7551 1.01 0.96,1.06 1767 17206 0.5768 0.942 0.763,1.16 90 850
781.1 Loss of height symptoms Both 0.6516 0.953 0.773,1.17 91 890 0.5768 0.942 0.763,1.16 90 850
782.3 Edema symptoms Both 0.6442 1.01 0.976,1.04 4591 30849 0.8892 1.0 0.97,1.04 4284 29903
782.6 Pallor and flushing symptoms Both 0.3357 1.04 0.961,1.12 679 6769 0.2594 1.05 0.966,1.14 639 6586
783 Fever of unknown origin symptoms Both 0.02844 1.04 1.0,1.07 4616 33703 0.4036 1.06 0.928,1.2 239 2399
783.1 Postprocedural fever symptoms Both 0.2472 1.08 0.949,1.23 248 2473 0.4036 1.06 0.928,1.2 239 2399
785 Abdominal pain symptoms Both 0.6501 0.995 0.974,1.02 13257 25098 0.6714 0.995 0.974,1.02 12653 24394
788 Syncope and collapse symptoms Both 0.04487 1.04 1.0,1.08 3017 29114 0.05058 1.04 1.0,1.08 2877 28109
789 Nausea and vomiting symptoms Both 0.3119 1.01 0.988,1.04 8497 29838 0.0195 1.11 1.02,1.2 598 6167
789.1 Persistent vomiting symptoms Both 0.04355 1.09 1.0,1.18 634 6330 0.0195 1.11 1.02,1.2 598 6167
790 Nonspecific findings on examination of blood symptoms Both 0.5433 1.02 0.967,1.07 1740 17356 0.7161 0.965 0.795,1.17 114 1188
790.1 Elevated sedimentation rate symptoms Both 0.6223 1.04 0.883,1.23 158 1580 0.5346 1.06 0.889,1.25 149 1524
790.6 Other abnormal blood chemistry symptoms Both 0.3342 1.02 0.985,1.05 4849 31554 0.4498 1.01 0.981,1.04 4578 30600
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.5224 0.954 0.827,1.1 204 2026 0.5012 0.951 0.823,1.1 198 1979
790.9 Abnormal arterial blood gases symptoms Both 0.8892 0.987 0.819,1.19 123 1230 0.7161 0.965 0.795,1.17 114 1188
791 Gangrene symptoms Both 0.8913 1.01 0.879,1.16 212 2104 0.9057 1.01 0.876,1.16 207 2010
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.4246 1.02 0.973,1.07 2171 11972 0.6622 0.984 0.915,1.06 816 7668
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.695 0.986 0.917,1.06 841 7806 0.6622 0.984 0.915,1.06 816 7668
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.4009 0.964 0.886,1.05 588 5848 0.8128 1.01 0.955,1.06 1531 15998
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.6383 1.01 0.962,1.06 1661 16601 0.8128 1.01 0.955,1.06 1531 15998
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.6871 0.98 0.889,1.08 433 4330 0.2716 0.943 0.85,1.05 387 4189
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.9268 0.998 0.948,1.05 1632 15619 0.984 1.0 0.848,1.18 147 1605
795.8 Abnormal tumor markers symptoms Both 0.9908 1.0 0.95,1.05 1698 13664 0.984 1.0 0.848,1.18 147 1605
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.7211 0.972 0.831,1.14 167 1662 0.984 1.0 0.848,1.18 147 1605
796 Elevated prostate specific antigen [PSA] symptoms Male 0.6012 1.01 0.961,1.07 1700 8294 0.7638 1.01 0.955,1.07 1623 7965
797 Shock symptoms Both 0.5129 0.968 0.879,1.07 445 4446 0.9057 1.01 0.863,1.18 169 1768
797.1 Cardiogenic shock symptoms Both 0.8851 1.01 0.869,1.18 183 1822 0.9057 1.01 0.863,1.18 169 1768
798 Malaise and fatigue symptoms Both 0.1629 1.02 0.993,1.04 8867 29476 0.6745 1.01 0.955,1.07 1242 13008
798.1 Chronic fatigue syndrome symptoms Both 0.7834 1.01 0.953,1.07 1349 13380 0.6745 1.01 0.955,1.07 1242 13008
799 Debility unspecified symptoms Both 0.3381 1.02 0.975,1.08 1672 16007 0.236 1.03 0.98,1.09 1552 15347
800 Fracture of lower limb injuries & poisonings Both 0.673 0.99 0.944,1.04 1879 18684 0.4256 0.952 0.843,1.07 281 2811
800.1 Fracture of neck of femur injuries & poisonings Both 0.2553 0.943 0.853,1.04 409 4028 0.263 0.943 0.851,1.04 394 3876
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.415 0.964 0.882,1.05 539 5364 0.3443 0.957 0.875,1.05 517 5181
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.7816 0.989 0.917,1.07 744 7420 0.7621 0.988 0.914,1.07 724 7220
800.4 Fracture of patella injuries & poisonings Both 0.4966 0.959 0.852,1.08 293 2904 0.4256 0.952 0.843,1.07 281 2811
801 Fracture of ankle and foot injuries & poisonings Both 0.1607 0.966 0.919,1.01 1804 17960 0.0798 0.939 0.875,1.01 882 8808
801.1 Fracture of foot injuries & poisonings Both 0.0863 0.941 0.878,1.01 913 9098 0.0798 0.939 0.875,1.01 882 8808
802 Fracture of pelvis injuries & poisonings Both 0.03873 0.886 0.791,0.994 321 3192 0.04677 0.888 0.79,0.998 305 3075
803 Fracture of upper limb injuries & poisonings Both 0.5105 1.02 0.967,1.07 1644 16288 0.8913 1.01 0.91,1.11 406 4058
803.1 Fracture of humerus injuries & poisonings Both 0.2992 1.05 0.961,1.14 592 5913 0.2438 1.05 0.965,1.15 570 5723
803.2 Fracture of radius and ulna injuries & poisonings Both 0.7834 1.01 0.942,1.08 899 8929 0.3228 0.934 0.817,1.07 239 2367
803.21 Colles' fracture injuries & poisonings Both 0.1923 0.916 0.803,1.05 248 2475 0.3228 0.934 0.817,1.07 239 2367
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.9886 1.0 0.906,1.11 419 4190 0.8913 1.01 0.91,1.11 406 4058
804 Fracture of hand or wrist injuries & poisonings Both 0.6577 0.987 0.932,1.05 1272 12504 0.5821 0.984 0.928,1.04 1229 12100
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.2979 1.03 0.971,1.1 1082 10755 0.4688 1.02 0.96,1.09 1023 10376
807 Fracture of ribs injuries & poisonings Both 0.4266 0.965 0.884,1.05 543 5428 0.2911 0.952 0.87,1.04 509 5247
809 Fracture of unspecified bones injuries & poisonings Both 0.2153 0.974 0.934,1.02 2426 23282 0.1361 0.968 0.927,1.01 2332 22500
817 Concussion injuries & poisonings Both 0.04842 1.08 1.0,1.16 771 7696 0.08395 1.07 0.991,1.15 750 7472
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.8128 0.984 0.864,1.12 240 2380 0.04932 0.79 0.625,0.999 81 797
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.7534 0.962 0.754,1.23 74 740 0.7603 0.963 0.753,1.23 73 712
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.02576 0.769 0.611,0.969 84 837 0.04932 0.79 0.625,0.999 81 797
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.03251 1.05 1.0,1.11 1782 17605 0.07328 1.05 0.996,1.1 1726 17041
830 Dislocation injuries & poisonings Both 0.859 0.997 0.96,1.03 3129 28682 0.9354 0.998 0.962,1.04 3048 27686
835 Internal derangement of knee injuries & poisonings Both 0.7228 1.01 0.961,1.06 1774 17453 0.7278 1.01 0.96,1.06 1732 16884
836 Traumatic arthropathy injuries & poisonings Both 0.8892 0.993 0.898,1.1 423 4213 0.9376 1.0 0.907,1.11 409 4032
840 Sprains and strains injuries & poisonings Both 0.4699 1.01 0.983,1.04 6106 31582 0.3606 1.02 0.977,1.07 2216 18913
840.1 Muscle/tendon sprain injuries & poisonings Both 0.09057 0.919 0.833,1.01 429 4269 0.07852 0.914 0.826,1.01 405 4085
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.9683 1.0 0.946,1.06 1343 13394 0.9908 1.0 0.945,1.06 1293 12850
840.3 Joint/ligament sprain injuries & poisonings Both 0.3917 1.02 0.976,1.07 2261 19530 0.3606 1.02 0.977,1.07 2216 18913
841 Sprains and strains of back and neck injuries & poisonings Both 0.7311 0.989 0.932,1.05 1175 11729 0.5754 0.983 0.924,1.04 1127 11332
842 Other sprains and strains injuries & poisonings Both 0.873 0.995 0.934,1.06 1079 10729 0.861 0.994 0.932,1.06 1043 10393
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.5998 1.01 0.965,1.06 1807 18037 0.6683 1.01 0.962,1.06 1684 17407
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.4227 1.03 0.958,1.11 797 7958 0.3524 1.04 0.961,1.12 745 7685
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.0861 1.09 0.988,1.21 398 3977 0.1107 1.09 0.981,1.2 387 3844
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.6457 0.988 0.937,1.04 1537 15333 0.3013 0.971 0.92,1.03 1416 14811
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.5559 1.04 0.915,1.18 254 2540 0.5943 1.04 0.911,1.18 246 2453
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.5649 1.04 0.914,1.18 262 2617 0.9268 0.994 0.872,1.13 247 2525
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.7709 1.01 0.951,1.07 1196 11925 0.8551 1.01 0.947,1.07 1155 11513
858 Complication of internal orthopedic device injuries & poisonings Both 0.0877 0.959 0.915,1.01 1892 18846 0.1005 0.961 0.915,1.01 1848 18277
859 Complication due to other implant and internal device injuries & poisonings Both 0.826 1.01 0.958,1.06 1820 18191 0.984 0.999 0.951,1.05 1725 17599
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.8128 1.0 0.969,1.04 3389 30552 0.1778 0.875 0.72,1.06 113 1131
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.6095 0.96 0.819,1.12 156 1551 0.6095 0.959 0.816,1.13 150 1505
870.2 Open wound of ear injuries & poisonings Both 0.5272 0.941 0.779,1.14 114 1131 0.3776 0.917 0.756,1.11 110 1091
870.3 Other open wound of head and face injuries & poisonings Both 0.7047 0.988 0.927,1.05 1064 10560 0.4732 0.977 0.916,1.04 1026 10186
870.4 Open wound of nose and sinus injuries & poisonings Both 0.6855 1.03 0.884,1.21 168 1667 0.6427 1.04 0.885,1.22 162 1598
870.5 Open wound of lip and mouth injuries & poisonings Both 0.6166 1.04 0.904,1.19 230 2293 0.8072 1.02 0.884,1.17 215 2209
870.6 Open wound of neck injuries & poisonings Both 0.06823 0.867 0.743,1.01 184 1833 0.1167 0.881 0.752,1.03 174 1769
870.8 Open wound of genital organs injuries & poisonings Both 0.07674 0.843 0.697,1.02 117 1170 0.1778 0.875 0.72,1.06 113 1131
871 Open wounds of extremities injuries & poisonings Both 0.4325 1.02 0.977,1.06 2705 26585 0.8017 0.981 0.841,1.14 182 1828
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.6053 0.974 0.882,1.08 438 4378 0.6776 0.979 0.885,1.08 425 4233
871.2 Open wound of finger(s) injuries & poisonings Both 0.6966 0.985 0.912,1.06 731 7291 0.6998 0.985 0.91,1.07 708 7021
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.03972 1.13 1.01,1.26 331 3277 0.02951 1.14 1.01,1.28 319 3183
871.4 Open wound of toe(s) injuries & poisonings Both 0.8395 0.985 0.848,1.14 191 1901 0.8017 0.981 0.841,1.14 182 1828
872 Traumatic amputation injuries & poisonings Both 0.3614 1.05 0.947,1.16 415 4129 0.4093 1.04 0.942,1.16 397 3991
873 Broken tooth injuries & poisonings Both 0.01125 1.24 1.05,1.46 148 1471 0.04808 1.19 1.0,1.41 137 1416
874 Complication of amputation stump injuries & poisonings Both 0.9311 0.992 0.829,1.19 122 1220 0.9311 0.992 0.827,1.19 119 1168
875 Non-healing surgical wound injuries & poisonings Both 0.1803 0.939 0.856,1.03 495 4950 0.2704 0.948 0.862,1.04 468 4773
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.6295 1.02 0.942,1.1 669 6680 0.5058 1.03 0.948,1.11 636 6445
907 Injuries to the nervous system injuries & poisonings Both 0.507 0.977 0.912,1.05 888 8852 0.5105 0.977 0.911,1.05 858 8525
910 Superficial injury, infected injuries & poisonings Both 0.6501 0.951 0.764,1.18 89 887 0.631 0.948 0.762,1.18 88 857
911 Blister injuries & poisonings Both 0.7295 0.974 0.838,1.13 185 1838 0.5188 0.951 0.816,1.11 176 1749
912 Insect bite injuries & poisonings Both 0.2767 0.939 0.838,1.05 321 3207 0.2489 0.933 0.83,1.05 303 3086
913 Toxic effect of venom injuries & poisonings Both 0.8337 1.01 0.887,1.16 247 2461 0.9462 1.0 0.876,1.15 237 2374
915 Superficial injury without mention of infection injuries & poisonings Both 0.04786 0.958 0.918,1.0 2368 23457 0.0413 0.956 0.915,0.998 2264 22632
916 Contusion injuries & poisonings Both 0.9886 1.0 0.964,1.04 3199 30228 0.8453 0.996 0.96,1.03 3076 29176
930 Allergic reaction to food injuries & poisonings Both 0.3273 1.04 0.959,1.14 597 5953 0.3656 1.04 0.955,1.13 574 5780
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.9616 0.998 0.913,1.09 530 5290 0.9204 1.0 0.918,1.1 516 5143
938 Dermatitis due to solar radiation injuries & poisonings Both 0.09638 1.03 0.995,1.06 4197 24407 0.2495 1.02 0.986,1.06 3769 23292
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.912 0.991 0.84,1.17 164 1640 0.7852 0.977 0.825,1.16 157 1588
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.1127 1.03 0.994,1.06 4001 24007 0.2495 1.02 0.986,1.06 3769 23292
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.542 1.05 0.889,1.25 140 1400 0.6166 1.05 0.877,1.25 131 1344
942 Infusion and transfusion reaction injuries & poisonings Both 0.3034 1.08 0.936,1.24 221 2205 0.2951 1.08 0.932,1.26 188 2141
946 Anaphylactic shock NOS injuries & poisonings Both 0.7379 1.02 0.917,1.13 385 3830 0.8433 1.01 0.909,1.12 366 3721
947 Urticaria injuries & poisonings Both 0.2612 1.04 0.971,1.12 889 8845 0.6471 1.02 0.947,1.09 840 8618
949 Allergies, other injuries & poisonings Both 0.07096 1.03 0.998,1.06 5269 26807 0.1483 1.02 0.992,1.05 4999 26064
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.6653 1.02 0.925,1.13 419 4176 0.6223 1.03 0.927,1.13 406 4055
957 Injury to other and unspecified nerves injuries & poisonings Both 0.912 1.01 0.838,1.22 116 1150 0.9333 1.01 0.834,1.22 114 1118
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.9354 0.997 0.937,1.06 1073 10721 0.07244 0.812 0.648,1.02 81 876
958.1 Postoperative shock injuries & poisonings Both 0.07638 1.17 0.983,1.4 133 1325 0.09354 1.17 0.974,1.39 129 1280
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.2133 0.873 0.706,1.08 92 911 0.07244 0.812 0.648,1.02 81 876
960 Poisoning by antibiotics injuries & poisonings Both 0.2618 1.03 0.981,1.07 2108 18753 0.3334 1.03 0.972,1.09 1339 13452
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.7925 1.02 0.87,1.2 158 1552 0.9954 1.0 0.843,1.19 138 1514
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.4395 1.02 0.968,1.08 1414 13864 0.3334 1.03 0.972,1.09 1339 13452
961 Poisoning by other anti-infectives injuries & poisonings Both 0.6012 1.03 0.933,1.13 470 4694 0.5702 0.98 0.915,1.05 890 8907
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.5598 0.98 0.917,1.05 939 9190 0.5702 0.98 0.915,1.05 890 8907
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.5728 1.03 0.939,1.12 561 5601 0.7464 0.98 0.865,1.11 272 2945
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.0869 1.11 0.985,1.25 308 3069 0.1062 1.11 0.978,1.26 279 2979
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.9183 0.994 0.883,1.12 305 3029 0.7464 0.98 0.865,1.11 272 2945
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.1795 1.03 0.986,1.08 2031 19919 0.4539 1.02 0.97,1.07 1684 18983
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.1762 1.03 0.986,1.08 1980 19507 0.4539 1.02 0.97,1.07 1684 18983
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.871 0.993 0.909,1.08 538 5360 0.5585 0.972 0.884,1.07 465 4911
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.8974 0.994 0.908,1.09 509 5070 0.5585 0.972 0.884,1.07 465 4911
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.5808 1.02 0.948,1.1 753 7525 0.861 0.981 0.794,1.21 95 935
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.6577 0.987 0.933,1.04 1305 12848 0.3565 0.973 0.917,1.03 1212 12479
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.7727 1.03 0.838,1.27 98 967 0.861 0.981 0.794,1.21 95 935
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.3936 0.911 0.737,1.13 86 850 0.3926 0.91 0.734,1.13 85 831
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.7063 0.988 0.925,1.05 1000 9986 0.5559 0.98 0.917,1.05 946 9718
969 Poisoning by psychotropic agents injuries & poisonings Both 0.04753 0.872 0.762,0.998 234 2331 0.0631 0.878 0.766,1.01 226 2275
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.9863 1.0 0.757,1.33 56 546 0.5916 0.923 0.689,1.24 52 536
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.8356 1.01 0.886,1.16 228 2269 0.1706 1.17 0.936,1.46 81 841
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.6622 0.946 0.738,1.21 66 637 0.879 1.02 0.783,1.33 58 611
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.2168 1.14 0.924,1.42 86 860 0.1706 1.17 0.936,1.46 81 841
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.1556 1.17 0.941,1.46 90 896 0.09311 1.22 0.967,1.54 83 867
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.6982 0.954 0.752,1.21 69 686 0.6855 0.952 0.751,1.21 69 679
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.14 1.22 0.937,1.59 60 600 0.06966 1.3 0.979,1.71 54 591
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.4634 0.981 0.931,1.03 1565 14843 0.4207 0.978 0.927,1.03 1465 14396
979 Adverse drug events and drug allergies injuries & poisonings Both 0.6152 0.989 0.945,1.03 2116 20636 0.4667 0.983 0.938,1.03 1957 20066
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.6966 0.958 0.772,1.19 91 904 0.5093 0.927 0.741,1.16 84 872
990 Effects radiation NOS injuries & poisonings Both 0.3013 1.02 0.981,1.06 2707 23906 0.5781 1.01 0.97,1.06 2344 23204
994 Sepsis and SIRS injuries & poisonings Both 0.118 1.04 0.99,1.09 1724 17160 0.1782 1.07 0.97,1.18 431 4671
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.9572 1.0 0.881,1.14 248 2472 0.4656 1.05 0.917,1.21 226 2381
994.2 Sepsis injuries & poisonings Both 0.1469 1.04 0.987,1.09 1636 16281 0.1782 1.07 0.97,1.18 431 4671
994.21 Septic shock injuries & poisonings Both 0.1159 1.08 0.982,1.18 484 4840 0.1782 1.07 0.97,1.18 431 4671
1000 Burns injuries & poisonings Both 0.0975 1.07 0.988,1.16 638 6350 0.08375 1.08 0.99,1.17 607 6154
1001 Foreign body injury injuries & poisonings Both 0.5768 0.988 0.947,1.03 2372 22762 0.3589 0.98 0.938,1.02 2252 21938
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.3055 1.02 0.986,1.05 4830 32603 0.6776 1.01 0.976,1.04 4496 31640
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.7345 1.01 0.951,1.07 1136 11344 0.8091 1.01 0.947,1.07 1090 11002
1005 Other symptoms injuries & poisonings Both 0.04613 1.03 1.0,1.05 7724 30626 0.08551 1.02 0.997,1.05 7339 29703
1006 Crushing injury injuries & poisonings Both 0.1816 0.915 0.804,1.04 245 2437 0.1884 0.916 0.803,1.04 238 2363
1007 Injury to blood vessels injuries & poisonings Both 0.5495 1.03 0.93,1.15 411 4106 0.3192 1.06 0.949,1.18 389 3972
1008 Crushing or internal injury to organs injuries & poisonings Both 0.4102 0.972 0.909,1.04 934 9331 0.1531 0.951 0.887,1.02 879 9023
1009 Injury, NOS injuries & poisonings Both 0.7413 1.0 0.981,1.03 9284 29063 0.9908 1.0 0.976,1.02 8942 28097
1010 Other tests injuries & poisonings Both 0.01081 1.03 1.01,1.05 19027 19331 0.01774 1.03 1.0,1.05 18137 18913
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.2388 1.02 0.989,1.05 5922 32336 0.235 1.02 0.989,1.05 5621 31332
1012 Late effect injuries & poisonings Both 0.5902 1.02 0.948,1.1 792 7909 0.6194 1.02 0.945,1.1 743 7641
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.04808 1.04 1.0,1.09 2459 23709 0.02523 1.05 1.01,1.1 2277 22853
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.5047 1.05 0.905,1.22 177 1770 0.3228 1.08 0.926,1.26 166 1700
1015 Effects of other external causes injuries & poisonings Both 0.5284 1.01 0.981,1.04 5744 32595 0.5998 1.01 0.979,1.04 5479 31552
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.9484 0.999 0.956,1.04 2208 21537 0.826 0.995 0.951,1.04 2072 20748
1100 Family history injuries & poisonings Both 0.2582 1.08 0.943,1.25 222 2220 0.2864 1.08 0.937,1.25 210 2157
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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