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MGI PRS for Thyroid cancer(193) based on UKB GWAS (PheCode)
GWAS reference: UKB_GWAS GWAS source: UKB GWAS (PheCode) PRS method: P&T
PRSweb LD reference: UKB GWAS phenotype: Thyroid cancer PRSweb date: 2020-06-20
GWAS ID: UKBB_SAIGE_HRC_X193 GWAS URL: ftp://share.sph.umich.edu/UKBB_SAIGE_HRC/ Genome build: GRCh37/hg19
PRS tuning parameter: P<=2e-06 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.1968 1.03 0.986,1.07 2317 23065 0.5875 1.02 0.952,1.09 919 9144
008.5 Bacterial enteritis infectious diseases Both 0.2466 1.04 0.975,1.1 1090 10875 0.2455 1.04 0.973,1.11 884 8726
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.317 1.04 0.967,1.11 896 8939 0.2455 1.04 0.973,1.11 884 8726
008.6 Viral Enteritis infectious diseases Both 0.8531 0.992 0.912,1.08 590 5900 0.811 0.99 0.909,1.08 578 5760
010 Tuberculosis infectious diseases Both 0.4732 0.946 0.814,1.1 195 1948 0.06607 1.02 0.999,1.04 18631 18930
031 Diseases due to other mycobacteria infectious diseases Both 0.1358 0.83 0.649,1.06 73 722 0.171 0.843 0.66,1.08 72 707
038 Septicemia infectious diseases Both 0.5093 1.02 0.97,1.06 2043 20052 0.4055 1.03 0.963,1.1 938 9287
038.1 Gram negative septicemia infectious diseases Both 0.861 0.992 0.902,1.09 459 4559 0.9931 1.0 0.91,1.1 454 4448
038.2 Gram positive septicemia infectious diseases Both 0.005623 0.792 0.671,0.934 184 1840 0.007586 0.797 0.675,0.942 180 1792
038.3 Bacteremia infectious diseases Both 0.5 1.02 0.958,1.09 955 9489 0.4055 1.03 0.963,1.1 938 9287
041 Bacterial infection NOS infectious diseases Both 0.3936 1.01 0.983,1.05 4641 32299 0.04074 0.859 0.743,0.994 228 2211
041.1 Staphylococcus infections infectious diseases Both 0.4335 0.978 0.925,1.03 1390 13828 0.1954 0.946 0.869,1.03 631 6245
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.5534 1.02 0.947,1.11 714 7071 0.4467 1.03 0.953,1.11 704 6929
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.1742 0.943 0.867,1.03 639 6376 0.1954 0.946 0.869,1.03 631 6245
041.2 Streptococcus infection infectious diseases Both 0.9638 0.999 0.944,1.06 1316 13131 0.5649 1.04 0.905,1.2 205 2003
041.21 Rheumatic fever / chorea infectious diseases Both 0.5861 1.04 0.903,1.2 205 2047 0.5649 1.04 0.905,1.2 205 2003
041.4 E. coli infectious diseases Both 0.3855 0.971 0.908,1.04 949 9462 0.5521 0.98 0.916,1.05 929 9250
041.8 H. pylori infectious diseases Both 0.2388 1.09 0.944,1.26 190 1892 0.1901 1.1 0.952,1.28 183 1838
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.03715 0.856 0.739,0.991 228 2265 0.04074 0.859 0.743,0.994 228 2211
053 Herpes zoster infectious diseases Both 0.4581 0.978 0.921,1.04 1184 11746 0.7211 0.972 0.83,1.14 160 1612
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.7345 0.973 0.833,1.14 166 1655 0.7211 0.972 0.83,1.14 160 1612
054 Herpes simplex infectious diseases Both 0.6039 1.02 0.958,1.08 1235 12278 0.5888 1.02 0.959,1.08 1213 11980
070 Viral hepatitis infectious diseases Both 0.5383 1.03 0.947,1.11 661 6584 0.2455 1.04 0.973,1.11 903 9048
070.1 Viral hepatitis A infectious diseases Both 0.1738 0.839 0.652,1.08 67 660 0.2168 0.853 0.663,1.1 67 647
070.2 Viral hepatitis B infectious diseases Both 0.5248 1.05 0.901,1.23 162 1620 0.871 1.01 0.864,1.19 158 1584
070.3 Viral hepatitis C infectious diseases Both 0.871 1.01 0.915,1.11 439 4366 0.9954 1.0 0.905,1.1 427 4281
070.4 Chronic hepatitis infectious diseases Both 0.5284 1.05 0.899,1.23 161 1610 0.4508 1.06 0.908,1.24 157 1587
070.9 Hepatitis NOS infectious diseases Both 0.2606 1.04 0.972,1.11 924 9231 0.2455 1.04 0.973,1.11 903 9048
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.6383 0.957 0.798,1.15 122 1220 0.8831 1.02 0.825,1.25 94 934
071.1 HIV infection, symptomatic infectious diseases Both 0.7691 1.03 0.838,1.27 95 950 0.8831 1.02 0.825,1.25 94 934
078 Viral warts & HPV infectious diseases Both 0.984 1.0 0.96,1.04 2651 24185 0.8279 1.0 0.965,1.05 2595 23658
079 Viral infection infectious diseases Both 0.06918 1.03 0.998,1.06 5061 29504 0.984 1.0 0.919,1.09 567 5582
079.1 Varicella infection infectious diseases Both 0.02951 1.04 1.0,1.08 2940 25647 0.04074 1.04 1.0,1.08 2864 25094
079.2 Infectious mononucleosis infectious diseases Both 0.6607 1.03 0.9,1.18 213 2093 0.6776 1.03 0.899,1.18 211 2047
079.9 Viremia, NOS infectious diseases Both 0.863 0.993 0.912,1.08 579 5713 0.984 1.0 0.919,1.09 567 5582
080 Postoperative infection infectious diseases Both 0.07762 1.04 0.996,1.08 2586 25769 0.05129 1.04 1.0,1.08 2536 25203
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.5754 1.02 0.961,1.07 1364 13616 0.4677 1.02 0.965,1.08 1342 13331
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.1581 0.945 0.874,1.02 700 6990 0.1318 0.941 0.87,1.02 688 6814
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.04898 1.04 1.0,1.09 2379 23308 0.5794 0.961 0.836,1.11 213 2154
110.1 Dermatophytosis infectious diseases Both 0.06607 1.04 0.997,1.09 2164 21163 0.2317 1.05 0.968,1.14 562 5580
110.11 Dermatophytosis of nail infectious diseases Both 0.06761 1.05 0.996,1.12 1264 12489 0.1045 1.05 0.99,1.11 1241 12253
110.12 Althete's foot infectious diseases Both 0.0912 1.07 0.989,1.17 593 5884 0.1963 1.06 0.972,1.15 578 5786
110.13 Dermatophytosis of the body infectious diseases Both 0.3112 1.04 0.96,1.13 570 5682 0.2317 1.05 0.968,1.14 562 5580
110.2 Dermatomycoses infectious diseases Both 0.6516 1.03 0.912,1.16 283 2812 0.695 1.02 0.907,1.16 273 2742
112 Candidiasis infectious diseases Both 0.01995 1.05 1.01,1.09 2931 25310 0.15 1.07 0.977,1.16 532 5319
112.3 Candidiasis of skin and nails infectious diseases Both 0.2547 1.05 0.964,1.15 546 5450 0.15 1.07 0.977,1.16 532 5319
117 Mycoses infectious diseases Both 0.6026 1.02 0.935,1.12 494 4925 0.3304 1.1 0.906,1.34 105 1024
117.1 Histoplasmosis infectious diseases Both 0.2218 1.15 0.917,1.45 66 660 0.1517 1.18 0.94,1.49 65 645
117.4 Aspergillosis infectious diseases Both 0.3289 1.1 0.906,1.34 105 1045 0.3304 1.1 0.906,1.34 105 1024
130 Spirochetal infection infectious diseases Both 0.4875 0.935 0.772,1.13 118 1177 0.2729 0.875 0.69,1.11 83 845
130.1 Lyme disease infectious diseases Both 0.2624 0.875 0.693,1.1 86 860 0.2729 0.875 0.69,1.11 83 845
132 Infestation (lice, mites) infectious diseases Both 0.5508 1.05 0.891,1.24 146 1460 0.492 1.06 0.898,1.25 146 1429
134 Helminthiases infectious diseases Both 0.5164 1.09 0.835,1.43 54 540 0.4603 1.11 0.844,1.45 54 524
136 Other infectious and parasitic diseases infectious diseases Both 0.2518 1.02 0.983,1.07 2438 24314 0.1429 1.03 0.99,1.08 2386 23781
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.5741 0.983 0.925,1.04 1166 11657 0.6486 0.986 0.928,1.05 1149 11436
145 Cancer of mouth neoplasms Both 0.7278 1.01 0.952,1.07 1182 11759 0.9954 1.0 0.855,1.17 168 1695
145.1 Cancer of lip neoplasms Both 0.4613 0.908 0.703,1.17 69 690 0.4592 0.908 0.704,1.17 69 682
145.2 Cancer of tongue neoplasms Both 0.1343 1.07 0.98,1.16 550 5486 0.2642 1.05 0.963,1.15 533 5392
145.3 Cancer of major salivary glands neoplasms Both 0.9247 1.01 0.896,1.13 310 3093 0.865 1.01 0.897,1.14 292 3035
145.4 Cancer of the gums neoplasms Both 0.9268 1.01 0.852,1.19 143 1419 0.9162 0.991 0.837,1.17 142 1401
145.5 Cancer of the mouth floor neoplasms Both 0.8913 1.01 0.866,1.18 173 1723 0.9954 1.0 0.855,1.17 168 1695
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.6209 1.02 0.955,1.08 1124 11202 0.9333 1.01 0.874,1.16 205 2024
149.1 Cancer of oropharynx neoplasms Both 0.4169 1.05 0.932,1.19 291 2892 0.414 1.05 0.932,1.19 287 2853
149.2 Cancer of nasopharynx neoplasms Both 0.514 0.93 0.747,1.16 87 855 0.5236 0.93 0.743,1.16 82 839
149.3 Cancer of hypopharynx neoplasms Both 0.4539 0.905 0.697,1.18 68 680 0.3273 0.874 0.668,1.14 64 671
149.4 Cancer of larynx neoplasms Both 0.182 1.08 0.966,1.2 332 3314 0.2377 1.07 0.957,1.19 316 3264
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.5023 0.969 0.883,1.06 505 5041 0.3258 0.954 0.868,1.05 487 4962
149.9 Cancer of of nasal cavities neoplasms Both 0.7745 1.02 0.888,1.17 208 2067 0.9333 1.01 0.874,1.16 205 2024
150 Cancer of esophagus neoplasms Both 0.7311 0.982 0.884,1.09 378 3776 0.6124 0.973 0.874,1.08 362 3705
151 Cancer of stomach neoplasms Both 0.01259 0.878 0.792,0.972 430 4292 0.00955 0.872 0.786,0.967 423 4216
153 Colorectal cancer neoplasms Both 0.1291 0.955 0.899,1.01 1196 11882 0.975 1.0 0.925,1.08 664 6528
153.2 Colon cancer neoplasms Both 0.151 0.952 0.889,1.02 941 9327 0.139 0.95 0.888,1.02 931 9146
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.8453 0.992 0.917,1.07 669 6663 0.975 1.0 0.925,1.08 664 6528
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.8204 0.989 0.895,1.09 418 4180 0.5445 1.04 0.921,1.17 276 2790
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.5358 1.04 0.923,1.17 285 2850 0.5445 1.04 0.921,1.17 276 2790
157 Pancreatic cancer neoplasms Both 0.5768 0.973 0.882,1.07 430 4292 0.5082 0.967 0.876,1.07 421 4213
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.7047 1.01 0.956,1.07 1369 13455 0.7889 1.01 0.953,1.07 1331 13199
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.6592 1.02 0.945,1.09 779 7785 0.2594 1.08 0.948,1.22 249 2495
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.8072 0.981 0.843,1.14 183 1830 0.7079 0.971 0.831,1.13 175 1792
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.5 0.939 0.783,1.13 133 1330 0.5458 0.945 0.787,1.13 131 1312
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.1945 1.09 0.959,1.23 255 2550 0.2594 1.08 0.948,1.22 249 2495
164 Cancer of intrathoracic organs neoplasms Both 0.157 1.15 0.948,1.4 111 1110 0.1897 1.14 0.936,1.39 105 1094
165 Cancer within the respiratory system neoplasms Both 0.8395 1.01 0.941,1.08 945 9436 0.695 1.01 0.945,1.09 840 8549
165.1 Cancer of bronchus; lung neoplasms Both 0.4539 1.03 0.958,1.1 874 8724 0.695 1.01 0.945,1.09 840 8549
170 Cancer of bone and connective tissue neoplasms Both 0.6368 1.01 0.961,1.07 1538 15304 0.07413 1.06 0.994,1.13 1062 10734
170.1 Bone cancer neoplasms Both 0.07943 0.929 0.857,1.01 668 6660 0.06026 0.923 0.849,1.0 646 6544
170.2 Cancer of connective tissue neoplasms Both 0.0912 1.05 0.992,1.12 1097 10941 0.07413 1.06 0.994,1.13 1062 10734
172 Skin cancer neoplasms Both 0.3548 1.01 0.986,1.04 7099 27878 0.879 0.995 0.937,1.06 1187 10103
172.1 Melanomas of skin, dx or hx neoplasms Both 0.6792 0.991 0.952,1.03 2701 21867 0.4487 0.984 0.944,1.03 2562 21098
172.11 Melanomas of skin neoplasms Both 0.4842 0.985 0.946,1.03 2624 21526 0.4487 0.984 0.944,1.03 2562 21098
172.2 Other non-epithelial cancer of skin neoplasms Both 0.1811 1.02 0.991,1.05 5888 25669 0.08128 1.04 0.995,1.1 1875 14333
172.21 Basal cell carcinoma neoplasms Both 0.1483 1.03 0.99,1.07 2988 20068 0.1413 1.03 0.99,1.07 2934 19674
172.22 Squamous cell carcinoma neoplasms Both 0.07079 1.04 0.996,1.1 1917 14585 0.08128 1.04 0.995,1.1 1875 14333
172.3 Carcinoma in situ of skin neoplasms Both 0.863 0.995 0.937,1.06 1215 10290 0.879 0.995 0.937,1.06 1187 10103
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.1766 1.04 0.984,1.09 1575 15093 0.1694 1.04 0.985,1.09 1529 14763
174 Breast cancer neoplasms Both 0.01175 1.05 1.01,1.1 2694 13131 0.7096 1.03 0.889,1.19 198 2000
174.1 Breast cancer [female] neoplasms Female 0.01047 1.06 1.01,1.1 2605 12548 0.003236 1.07 1.02,1.11 2501 12155
174.11 Malignant neoplasm of female breast neoplasms Female 0.005888 1.06 1.02,1.11 2565 12510 0.003236 1.07 1.02,1.11 2501 12155
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.8185 1.02 0.881,1.17 206 2051 0.7096 1.03 0.889,1.19 198 2000
175 Acquired absence of breast neoplasms Female 0.03981 1.07 1.0,1.14 978 9172 0.02188 1.08 1.01,1.15 958 8901
180 Cervical cancer and dysplasia neoplasms Female 0.4236 1.02 0.965,1.09 1182 10494 0.4786 1.03 0.956,1.1 838 7637
180.1 Cervical cancer neoplasms Female 0.673 0.979 0.888,1.08 430 4300 0.6622 0.978 0.887,1.08 419 4176
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.399 1.03 0.961,1.11 857 7886 0.4786 1.03 0.956,1.1 838 7637
182 Malignant neoplasm of uterus neoplasms Female 0.975 1.0 0.923,1.09 643 6390 0.9419 1.0 0.924,1.09 626 6234
184 Cancer of other female genital organs neoplasms Female 0.1652 0.952 0.888,1.02 910 8957 0.5035 0.969 0.884,1.06 514 5113
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.08128 0.919 0.835,1.01 491 4888 0.2489 0.937 0.838,1.05 360 3560
184.11 Malignant neoplasm of ovary neoplasms Female 0.2037 0.931 0.834,1.04 367 3659 0.2489 0.937 0.838,1.05 360 3560
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.5508 0.973 0.889,1.06 526 5253 0.5035 0.969 0.884,1.06 514 5113
185 Cancer of prostate neoplasms Male 0.2649 1.03 0.98,1.08 2432 8825 0.1897 1.03 0.985,1.08 2396 8686
187 Cancer of other male genital organs neoplasms Male 0.07244 0.892 0.788,1.01 276 2723 0.07586 0.849 0.708,1.02 141 1372
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.7834 1.03 0.838,1.26 96 960 0.7603 1.03 0.841,1.27 96 942
187.2 Malignant neoplasm of testis neoplasms Male 0.0912 0.857 0.716,1.03 144 1387 0.07586 0.849 0.708,1.02 141 1372
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.0955 1.04 0.994,1.08 2552 20553 0.302 1.05 0.961,1.14 599 5728
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.3055 1.03 0.973,1.09 1261 12588 0.002884 1.24 1.08,1.42 200 1969
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.2296 1.04 0.977,1.1 1083 10823 0.1452 1.05 0.984,1.11 1056 10610
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.005623 1.22 1.06,1.4 202 2010 0.002884 1.24 1.08,1.42 200 1969
189.2 Cancer of bladder neoplasms Both 0.2698 1.03 0.978,1.08 1575 13516 0.2884 1.03 0.975,1.09 1442 12321
189.21 Malignant neoplasm of bladder neoplasms Both 0.3724 1.02 0.971,1.08 1456 12558 0.2884 1.03 0.975,1.09 1442 12321
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.4188 1.04 0.952,1.13 601 5841 0.302 1.05 0.961,1.14 599 5728
190 Cancer of eye neoplasms Both 0.9226 0.99 0.813,1.21 114 1125 0.9419 0.993 0.814,1.21 113 1114
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.6501 1.02 0.949,1.09 904 9040 0.3311 1.05 0.954,1.15 473 4740
191.1 Cancer of brain and nervous system neoplasms Both 0.9572 1.0 0.921,1.09 580 5800 0.3311 1.05 0.954,1.15 473 4740
191.11 Cancer of brain neoplasms Both 0.3475 1.05 0.953,1.15 483 4830 0.3311 1.05 0.954,1.15 473 4740
193 Thyroid cancer neoplasms Both 1.0E-15 1.32 1.24,1.42 798 7953 ,
194 Cancer of other endocrine glands neoplasms Both 0.8054 0.983 0.854,1.13 221 2207 0.5058 0.952 0.823,1.1 204 2207
195 Cancer, suspected or other neoplasms Both 0.1396 1.02 0.994,1.04 12134 23141 0.5875 1.02 0.952,1.09 919 8924
195.1 Malignant neoplasm, other neoplasms Both 0.1618 1.02 0.993,1.04 11693 23098 0.6792 1.01 0.981,1.03 11171 22958
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.2704 1.04 0.971,1.11 970 8963 0.5875 1.02 0.952,1.09 919 8924
196 Radiotherapy neoplasms Both 0.1117 1.04 0.991,1.09 2067 15612 0.2679 1.03 0.98,1.08 2005 15508
197 Chemotherapy neoplasms Both 0.008511 1.05 1.01,1.08 4051 21210 0.03467 1.04 1.0,1.07 3944 21080
198 Secondary malignant neoplasm neoplasms Both 0.1271 1.02 0.993,1.06 4986 21474 0.8299 1.01 0.897,1.15 276 2732
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.2138 1.02 0.986,1.06 3156 19844 0.6808 0.992 0.953,1.03 2847 19717
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.171 1.05 0.98,1.12 903 8847 0.5012 1.02 0.955,1.1 842 8791
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.4688 0.972 0.899,1.05 725 7166 0.4406 0.97 0.897,1.05 708 7114
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.6998 0.984 0.906,1.07 643 6395 0.4345 0.967 0.889,1.05 623 6356
198.5 Secondary malignancy of brain/spine neoplasms Both 0.1135 1.07 0.983,1.17 545 5421 0.2831 1.05 0.961,1.15 521 5376
198.6 Secondary malignancy of bone neoplasms Both 0.2449 1.05 0.97,1.13 712 6962 0.4457 1.03 0.953,1.11 669 6914
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.8091 1.01 0.899,1.15 287 2752 0.8299 1.01 0.897,1.15 276 2732
199 Neoplasm of uncertain behavior neoplasms Both 0.1102 1.03 0.994,1.06 4947 22823 0.8433 0.976 0.768,1.24 69 717
199.4 Neurofibromatosis neoplasms Both 0.9311 0.99 0.782,1.25 72 720 0.8433 0.976 0.768,1.24 69 717
200 Myeloproliferative disease neoplasms Both 0.6109 1.02 0.951,1.09 886 8851 0.5176 0.947 0.802,1.12 155 1584
200.1 Polycythemia vera neoplasms Both 0.6194 0.959 0.815,1.13 161 1610 0.5176 0.947 0.802,1.12 155 1584
201 Hodgkin's disease neoplasms Both 0.7379 0.97 0.81,1.16 138 1373 0.7568 0.971 0.806,1.17 129 1353
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.5821 1.02 0.96,1.08 1308 13070 0.1191 1.15 0.966,1.36 125 1279
202.2 Non-Hodgkins lymphoma neoplasms Both 0.2333 1.04 0.977,1.1 1141 11402 0.1191 1.15 0.966,1.36 125 1279
202.21 Nodular lymphoma neoplasms Both 0.5445 1.03 0.946,1.11 632 6320 0.6998 1.02 0.934,1.11 573 6203
202.22 Reticulosarcoma neoplasms Both 0.1742 1.12 0.951,1.32 137 1355 0.1782 1.12 0.949,1.32 132 1332
202.24 Large cell lymphoma neoplasms Both 0.09333 1.15 0.976,1.36 132 1300 0.1191 1.15 0.966,1.36 125 1279
204 Leukemia neoplasms Both 0.4217 1.04 0.95,1.13 545 5450 0.3532 1.08 0.923,1.25 173 1763
204.1 Lymphoid leukemia neoplasms Both 0.6966 1.03 0.889,1.19 187 1870 0.9141 1.01 0.848,1.2 130 1326
204.11 Lymphoid leukemia, acute neoplasms Both 0.3656 1.13 0.871,1.45 58 580 0.3664 1.13 0.868,1.47 55 571
204.12 Lymphoid leukemia, chronic neoplasms Both 0.8054 1.02 0.861,1.21 136 1350 0.9141 1.01 0.848,1.2 130 1326
204.2 Myeloid leukemia neoplasms Both 0.0912 1.12 0.982,1.29 206 2060 0.4295 1.08 0.898,1.29 121 1216
204.21 Myeloid leukemia, acute neoplasms Both 0.4613 1.07 0.894,1.28 124 1240 0.4295 1.08 0.898,1.29 121 1216
204.4 Multiple myeloma neoplasms Both 0.5636 1.05 0.899,1.22 180 1795 0.3532 1.08 0.923,1.25 173 1763
208 Benign neoplasm of colon neoplasms Both 0.02818 1.03 1.0,1.05 8098 29324 0.03631 1.03 1.0,1.05 7928 28703
209 Neuroendocrine tumors neoplasms Both 0.04266 0.863 0.749,0.995 222 2220 0.02344 0.845 0.731,0.977 214 2173
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.342 1.03 0.974,1.08 1584 15798 0.3954 1.02 0.971,1.08 1542 15473
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.1871 1.02 0.991,1.05 5807 30296 0.1923 1.02 0.991,1.05 5682 29677
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.1923 1.04 0.983,1.09 1556 15533 0.2735 1.03 0.977,1.09 1517 15181
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.2244 0.966 0.913,1.02 1405 13304 0.2178 0.965 0.912,1.02 1380 13121
214 Lipoma neoplasms Both 0.5929 0.983 0.925,1.05 1117 11124 0.3273 0.961 0.886,1.04 661 6634
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.4121 0.967 0.894,1.05 681 6793 0.3273 0.961 0.886,1.04 661 6634
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.5035 0.988 0.955,1.02 3594 32904 0.2636 0.98 0.946,1.02 3471 32257
216 Benign neoplasm of skin neoplasms Both 0.1578 1.02 0.993,1.04 9073 29036 0.2512 1.12 0.923,1.36 107 1070
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.2924 1.11 0.915,1.34 111 1093 0.2512 1.12 0.923,1.36 107 1070
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.07762 1.05 0.994,1.12 1150 11417 0.2421 1.04 0.975,1.11 1030 10347
217.1 Nevus, non-neoplastic neoplasms Both 0.2312 1.04 0.976,1.1 1063 10579 0.2421 1.04 0.975,1.11 1030 10347
218 Benign neoplasm of uterus neoplasms Female 0.09772 0.969 0.934,1.01 3552 13845 0.2123 0.974 0.934,1.02 2751 13310
218.1 Uterine leiomyoma neoplasms Female 0.6124 0.986 0.935,1.04 1506 13465 0.4955 0.981 0.929,1.04 1462 13087
218.2 Other benign neoplasm of uterus neoplasms Female 0.1607 0.971 0.932,1.01 2824 13698 0.2123 0.974 0.934,1.02 2751 13310
220 Benign neoplasm of ovary neoplasms Female 0.9397 0.997 0.926,1.07 763 7571 0.9908 1.0 0.927,1.08 747 7349
221 Benign neoplasm of other female genital organs neoplasms Female 0.8974 1.0 0.953,1.06 1666 12074 0.7482 1.01 0.958,1.06 1641 11725
222 Benign neoplasm of male genital organs neoplasms Male 0.6324 0.984 0.921,1.05 954 9116 0.7244 0.988 0.924,1.06 942 8982
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.139 1.04 0.987,1.1 1547 11080 0.1146 1.04 0.99,1.1 1534 10920
224 Benign neoplasm of eye neoplasms Both 0.8279 0.99 0.903,1.08 511 5062 0.8279 0.989 0.894,1.09 418 4147
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.8851 0.993 0.898,1.1 429 4230 0.8279 0.989 0.894,1.09 418 4147
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.8204 1.01 0.945,1.07 1039 10379 0.3126 1.07 0.939,1.22 237 2366
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.8147 0.991 0.923,1.07 817 8160 0.9705 0.999 0.929,1.07 796 7991
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.3631 1.06 0.933,1.21 242 2420 0.3126 1.07 0.939,1.22 237 2366
226 Benign neoplasm of thyroid glands neoplasms Both 0.5808 1.02 0.957,1.08 1082 10810 0.389 0.97 0.906,1.04 887 10810
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.7362 1.01 0.956,1.07 1387 13870 0.9099 0.994 0.893,1.11 363 3724
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.3199 1.05 0.951,1.17 375 3745 0.4188 1.04 0.94,1.16 354 3745
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.5984 0.979 0.903,1.06 644 6434 0.5768 0.976 0.898,1.06 585 6434
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.9977 1.0 0.899,1.11 373 3724 0.9099 0.994 0.893,1.11 363 3724
228 Hemangioma and lymphangioma, any site neoplasms Both 0.5623 0.984 0.934,1.04 1517 15150 0.8017 1.01 0.94,1.08 820 8327
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.7379 1.01 0.944,1.09 849 8478 0.8017 1.01 0.94,1.08 820 8327
229 Benign neoplasm of unspecified sites neoplasms Both 0.4909 1.01 0.983,1.04 6631 31223 0.4335 1.01 0.982,1.04 4714 29154
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.2748 1.02 0.987,1.05 4904 29712 0.4335 1.01 0.982,1.04 4714 29154
860 Bone marrow or stem cell transplant neoplasms Both 0.7129 0.965 0.8,1.16 127 1266 0.7413 0.969 0.801,1.17 124 1240
240 Simple and unspecified goiter endocrine/metabolic Both 0.455 0.972 0.901,1.05 767 7647 0.1371 0.94 0.867,1.02 666 7631
241 Nontoxic nodular goiter endocrine/metabolic Both 0.4159 1.02 0.975,1.06 2274 18240 0.1143 0.944 0.879,1.01 841 10045
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.1253 1.04 0.989,1.09 1795 16440 0.7762 0.992 0.94,1.05 1464 16407
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.6592 0.986 0.924,1.05 1017 10065 0.1143 0.944 0.879,1.01 841 10045
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.2208 0.961 0.903,1.02 1075 10635 0.4217 0.921 0.754,1.13 102 1158
242.1 Graves' disease endocrine/metabolic Both 0.4875 1.04 0.936,1.15 399 3965 0.7762 1.02 0.913,1.13 361 3959
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.3954 1.09 0.895,1.32 98 978 0.3162 1.12 0.901,1.38 80 977
242.3 Exophthalmos endocrine/metabolic Both 0.9036 1.01 0.887,1.15 245 2447 0.4217 0.921 0.754,1.13 102 1158
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.7129 0.966 0.802,1.16 116 1160 0.4217 0.921 0.754,1.13 102 1158
244 Hypothyroidism endocrine/metabolic Both 2.042E-6 0.933 0.907,0.96 6448 27183 2.512E-12 0.895 0.868,0.923 5428 26672
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.07943 1.05 0.994,1.11 1421 14153 0.01349 0.914 0.851,0.982 849 14125
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.01413 0.913 0.85,0.982 853 8502 0.006026 0.9 0.835,0.97 796 8488
244.4 Hypothyroidism NOS endocrine/metabolic Both 2.818E-6 0.932 0.905,0.96 5996 26719 2.512E-12 0.895 0.868,0.923 5428 26672
245 Thyroiditis endocrine/metabolic Both 0.02089 0.901 0.824,0.984 574 5720 0.03467 0.893 0.805,0.992 408 4527
245.2 Chronic thyroiditis endocrine/metabolic Both 0.1208 0.926 0.84,1.02 463 4617 0.03467 0.893 0.805,0.992 408 4527
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.05129 0.906 0.821,1.0 456 4533 0.03467 0.893 0.805,0.992 408 4527
246 Other disorders of thyroid endocrine/metabolic Both 3.89E-5 0.936 0.907,0.966 5018 25158 0.105 0.926 0.844,1.02 516 5640
246.2 Thyroid cyst endocrine/metabolic Both 0.8054 1.03 0.826,1.28 83 804 0.6138 0.939 0.737,1.2 71 801
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.125 0.933 0.854,1.02 568 5651 0.105 0.926 0.844,1.02 516 5640
249 Secondary diabetes mellitus endocrine/metabolic Both 0.9057 1.0 0.929,1.09 686 6849 0.8185 1.01 0.933,1.09 676 6723
250 Diabetes mellitus endocrine/metabolic Both 0.1611 1.02 0.993,1.04 10115 27568 0.8933 0.995 0.925,1.07 801 7989
250.1 Type 1 diabetes endocrine/metabolic Both 0.3206 1.03 0.969,1.1 1053 10521 0.3062 0.869 0.664,1.14 69 673
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.8913 0.984 0.776,1.25 80 792 0.9036 0.985 0.775,1.25 80 762
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.9977 1.0 0.872,1.15 235 2346 0.9817 1.0 0.873,1.15 233 2286
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.6839 1.03 0.908,1.16 280 2800 0.6223 1.03 0.913,1.16 277 2726
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.4571 0.948 0.824,1.09 238 2372 0.4285 0.945 0.82,1.09 234 2320
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.2825 0.863 0.659,1.13 70 690 0.3062 0.869 0.664,1.14 69 673
250.2 Type 2 diabetes endocrine/metabolic Both 0.4046 1.01 0.985,1.04 7035 26169 0.4613 0.965 0.879,1.06 510 4960
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.8933 1.01 0.834,1.23 120 1200 0.9057 0.988 0.809,1.21 117 1161
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.9954 1.0 0.941,1.06 1133 11056 0.9908 1.0 0.94,1.06 1109 10845
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.6324 0.983 0.914,1.06 826 8208 0.7015 0.986 0.916,1.06 805 8035
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.6998 0.989 0.937,1.04 1419 13969 0.7047 0.989 0.936,1.05 1388 13684
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.3273 0.954 0.869,1.05 513 5077 0.4613 0.965 0.879,1.06 510 4960
250.3 Insulin pump user endocrine/metabolic Both 0.3069 0.975 0.93,1.02 1884 17814 0.2564 0.972 0.926,1.02 1848 17456
250.4 Abnormal glucose endocrine/metabolic Both 0.1164 1.02 0.994,1.05 5404 26451 0.4207 1.01 0.982,1.05 4627 25344
250.41 Impaired fasting glucose endocrine/metabolic Both 0.354 1.03 0.971,1.09 1326 13130 0.317 1.03 0.973,1.09 1297 12856
250.42 Other abnormal glucose endocrine/metabolic Both 0.2891 1.02 0.986,1.05 4736 25883 0.4207 1.01 0.982,1.05 4627 25344
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.4426 0.913 0.723,1.15 78 747 0.4285 0.91 0.721,1.15 77 726
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.3963 1.03 0.966,1.09 1137 11335 0.3945 1.03 0.966,1.09 1114 11100
250.7 Diabetic retinopathy endocrine/metabolic Both 0.7889 0.99 0.921,1.06 821 8168 0.8933 0.995 0.925,1.07 801 7989
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.2512 0.95 0.871,1.04 595 5901 0.5728 0.978 0.903,1.06 690 6878
251.1 Hypoglycemia endocrine/metabolic Both 0.6516 0.982 0.908,1.06 702 7015 0.5728 0.978 0.903,1.06 690 6878
252 Disorders of parathyroid gland endocrine/metabolic Both 0.8147 0.994 0.947,1.04 1807 17879 0.869 0.991 0.885,1.11 324 3851
252.1 Hyperparathyroidism endocrine/metabolic Both 0.8511 0.995 0.946,1.05 1656 16459 0.7096 0.99 0.939,1.04 1556 16156
252.2 Hypoparathyroidism endocrine/metabolic Both 0.9683 0.998 0.9,1.11 393 3922 0.869 0.991 0.885,1.11 324 3851
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.6109 1.02 0.944,1.1 691 6893 0.01514 1.28 1.05,1.55 93 906
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.7998 1.02 0.882,1.18 205 2041 0.2143 1.16 0.919,1.46 71 715
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.208 1.16 0.921,1.46 72 720 0.2143 1.16 0.919,1.46 71 715
253.2 Pituitary hypofunction endocrine/metabolic Both 0.8892 1.01 0.869,1.17 184 1840 0.9441 1.01 0.862,1.17 177 1810
253.3 Diabetes insipidus endocrine/metabolic Both 0.7943 0.969 0.765,1.23 70 694 0.7621 0.964 0.76,1.22 69 674
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.3945 1.09 0.89,1.34 92 899 0.3828 1.1 0.891,1.35 88 883
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.0166 1.27 1.04,1.55 93 925 0.01514 1.28 1.05,1.55 93 906
255 Disorders of adrenal glands endocrine/metabolic Both 0.5875 1.02 0.958,1.08 1186 11860 0.3622 1.05 0.949,1.15 433 4410
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.3548 0.944 0.835,1.07 290 2886 0.7656 0.969 0.786,1.19 101 1040
255.11 Cushing's syndrome endocrine/metabolic Both 0.4508 0.936 0.788,1.11 144 1440 0.3981 0.927 0.777,1.11 138 1415
255.12 Hyperaldosteronism endocrine/metabolic Both 0.6761 0.958 0.781,1.17 106 1057 0.7656 0.969 0.786,1.19 101 1040
255.2 Adrenal hypofunction endocrine/metabolic Both 0.3873 1.04 0.949,1.14 477 4758 0.3622 1.05 0.949,1.15 433 4410
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.2333 1.06 0.963,1.17 451 4496 0.3622 1.05 0.949,1.15 433 4410
256 Ovarian dysfunction endocrine/metabolic Female 0.7516 0.989 0.922,1.06 859 8184 0.7745 1.01 0.927,1.11 523 5304
256.4 Polycystic ovaries endocrine/metabolic Female 0.6383 1.02 0.936,1.11 544 5436 0.7745 1.01 0.927,1.11 523 5304
257 Testicular dysfunction endocrine/metabolic Male 0.2642 1.04 0.969,1.12 747 7455 0.3648 1.04 0.96,1.12 711 7132
257.1 Testicular hypofunction endocrine/metabolic Male 0.3006 1.04 0.965,1.12 725 7234 0.3648 1.04 0.96,1.12 711 7132
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.4436 0.905 0.701,1.17 66 660 0.7691 1.03 0.839,1.27 90 897
258.1 Postablative ovarian failure endocrine/metabolic Female 0.9376 1.01 0.821,1.24 92 920 0.7691 1.03 0.839,1.27 90 897
259 Other endocrine disorders endocrine/metabolic Both 0.8995 1.0 0.933,1.08 759 7562 0.7798 1.01 0.938,1.09 728 7406
260 Protein-calorie malnutrition endocrine/metabolic Both 0.9772 1.0 0.959,1.04 2353 22279 0.2979 0.957 0.882,1.04 659 6608
260.1 Cachexia endocrine/metabolic Both 0.8017 0.983 0.862,1.12 239 2388 0.6353 0.968 0.847,1.11 234 2341
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.7709 0.992 0.938,1.05 1363 13589 0.9183 0.995 0.898,1.1 404 4049
260.22 Nutritional marasmus endocrine/metabolic Both 0.8166 0.988 0.892,1.09 413 4130 0.9183 0.995 0.898,1.1 404 4049
260.3 Adult failure to thrive endocrine/metabolic Both 0.1091 1.08 0.984,1.18 509 5051 0.1282 1.07 0.98,1.18 493 4955
260.6 Anorexia endocrine/metabolic Both 0.3048 0.958 0.884,1.04 677 6722 0.2979 0.957 0.882,1.04 659 6608
261 Vitamin deficiency endocrine/metabolic Both 0.02754 1.03 1.0,1.06 5614 30157 0.01288 1.04 1.01,1.07 5082 29317
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.9705 0.999 0.921,1.08 649 6482 0.9661 1.0 0.923,1.09 632 6341
261.4 Vitamin D deficiency endocrine/metabolic Both 0.0138 1.04 1.01,1.07 5264 29859 0.01288 1.04 1.01,1.07 5082 29317
262 Mineral deficiency NEC endocrine/metabolic Both 0.1213 1.06 0.986,1.13 854 8532 0.07244 1.07 0.994,1.14 832 8348
263 Other nutritional deficiency endocrine/metabolic Both 0.1995 1.07 0.966,1.18 412 4113 0.3508 1.05 0.948,1.16 398 4032
264 Lack of normal physiological development endocrine/metabolic Both 0.1982 1.1 0.95,1.28 175 1735 0.5585 1.08 0.833,1.4 59 600
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.7907 1.03 0.837,1.26 95 950 0.8337 1.02 0.83,1.26 93 930
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.6792 1.06 0.816,1.37 61 607 0.5585 1.08 0.833,1.4 59 600
269 Proteinuria endocrine/metabolic Both 0.0537 1.06 0.999,1.13 1079 10768 0.07413 1.06 0.994,1.13 1052 10533
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.1589 1.06 0.979,1.14 740 7378 0.5105 1.05 0.914,1.2 214 2125
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.1754 1.13 0.946,1.36 129 1283 0.4375 1.09 0.882,1.34 96 963
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.413 1.09 0.889,1.33 101 998 0.4375 1.09 0.882,1.34 96 963
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.526 1.07 0.865,1.33 81 810 0.4345 1.09 0.88,1.35 81 793
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.413 1.04 0.951,1.13 560 5581 0.5105 1.05 0.914,1.2 214 2125
270.32 Paraproteinemia endocrine/metabolic Both 0.4207 1.05 0.933,1.18 301 2982 0.5047 1.04 0.923,1.18 289 2923
270.33 Amyloidosis endocrine/metabolic Both 0.5689 1.08 0.831,1.4 55 550 0.5383 1.09 0.836,1.41 55 538
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.4603 1.05 0.92,1.2 218 2178 0.5105 1.05 0.914,1.2 214 2125
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.07413 1.04 0.996,1.09 1952 19491 0.5495 1.07 0.858,1.33 79 794
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.08511 1.04 0.994,1.09 1885 18823 0.08318 1.04 0.994,1.09 1848 18407
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.5321 1.07 0.861,1.34 81 810 0.5495 1.07 0.858,1.33 79 794
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.2393 1.01 0.991,1.04 14793 22696 0.4227 1.06 0.924,1.21 235 2363
272.1 Hyperlipidemia endocrine/metabolic Both 0.2249 1.01 0.991,1.04 14763 22682 0.0389 1.05 1.0,1.1 2226 15169
272.11 Hypercholesterolemia endocrine/metabolic Both 0.04677 1.03 1.0,1.07 4668 18640 0.04571 1.03 1.0,1.07 4577 18234
272.12 Hyperglyceridemia endocrine/metabolic Both 0.7278 0.988 0.923,1.06 945 9395 0.7278 0.988 0.922,1.06 917 9212
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.0309 1.05 1.0,1.1 2272 15492 0.0389 1.05 1.0,1.1 2226 15169
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.4227 1.06 0.925,1.2 244 2425 0.4227 1.06 0.924,1.21 235 2363
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.04365 0.953 0.909,0.999 1971 18337 0.5741 1.05 0.886,1.24 138 1343
274.1 Gout endocrine/metabolic Both 0.03467 0.949 0.904,0.996 1879 17712 0.6823 0.985 0.915,1.06 776 7743
274.11 Gouty arthropathy endocrine/metabolic Both 0.4207 0.97 0.902,1.04 793 7891 0.6823 0.985 0.915,1.06 776 7743
274.2 Crystal arthropathies endocrine/metabolic Both 0.7211 1.03 0.871,1.22 146 1425 0.5741 1.05 0.886,1.24 138 1343
274.21 Chondrocalcinosis endocrine/metabolic Both 0.5117 1.06 0.894,1.25 140 1363 0.5741 1.05 0.886,1.24 138 1343
275 Disorders of mineral metabolism endocrine/metabolic Both 0.05623 1.04 0.999,1.07 3252 30253 0.5188 1.09 0.845,1.4 69 689
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.241 1.04 0.973,1.12 845 8441 0.2366 1.04 0.973,1.12 816 8288
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.0263 1.05 1.01,1.09 2502 24757 0.1493 1.05 0.983,1.12 1002 10026
275.51 Hypocalcemia endocrine/metabolic Both 0.005888 1.11 1.03,1.2 722 7203 0.1698 1.06 0.975,1.16 566 7075
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.1426 1.05 0.984,1.12 1024 10193 0.1493 1.05 0.983,1.12 1002 10026
275.6 Hypercalcemia endocrine/metabolic Both 0.9661 0.999 0.937,1.06 1043 10415 0.8913 1.0 0.941,1.07 994 10222
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.2979 1.01 0.988,1.04 7227 30901 0.561 1.06 0.869,1.29 94 969
276.1 Electrolyte imbalance endocrine/metabolic Both 0.02884 1.03 1.0,1.07 4833 28673 0.01905 1.06 1.01,1.12 1581 15811
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.1603 1.07 0.972,1.19 415 4115 0.1242 1.08 0.979,1.2 409 4041
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.02818 1.05 1.01,1.11 1857 17982 0.02291 1.06 1.01,1.11 1832 17625
276.13 Hyperpotassemia endocrine/metabolic Both 0.1567 1.03 0.988,1.08 2238 20576 0.1067 1.04 0.992,1.08 2204 20170
276.14 Hypopotassemia endocrine/metabolic Both 0.01995 1.06 1.01,1.12 1626 16160 0.01905 1.06 1.01,1.12 1581 15811
276.4 Acid-base balance disorder endocrine/metabolic Both 0.2679 1.03 0.978,1.08 1593 15855 0.3483 1.05 0.944,1.18 345 3427
276.41 Acidosis endocrine/metabolic Both 0.3899 1.02 0.969,1.08 1357 13508 0.2466 1.03 0.978,1.09 1345 13238
276.42 Alkalosis endocrine/metabolic Both 0.4721 1.04 0.933,1.16 350 3498 0.3483 1.05 0.944,1.18 345 3427
276.5 Hypovolemia endocrine/metabolic Both 0.798 1.0 0.97,1.04 3615 28901 0.6209 1.01 0.974,1.04 3529 28288
276.6 Fluid overload endocrine/metabolic Both 0.5012 0.978 0.917,1.04 1046 10404 0.6138 0.983 0.922,1.05 1024 10192
276.8 Polydipsia endocrine/metabolic Both 0.3606 1.09 0.902,1.33 99 990 0.561 1.06 0.869,1.29 94 969
277 Other disorders of metabolism endocrine/metabolic Both 0.1963 1.03 0.982,1.09 1534 15324 0.9311 0.996 0.917,1.08 593 5921
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.2673 1.07 0.947,1.22 252 2520 0.2685 1.07 0.946,1.22 247 2470
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.3882 1.04 0.952,1.13 547 5456 0.3597 1.04 0.954,1.14 543 5359
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.6295 1.02 0.942,1.1 675 6743 0.3837 1.04 0.953,1.13 558 5515
277.51 Lipoprotein disorders endocrine/metabolic Both 0.4446 1.03 0.949,1.13 567 5665 0.3837 1.04 0.953,1.13 558 5515
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.9705 1.0 0.923,1.09 610 6090 0.9311 0.996 0.917,1.08 593 5921
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.869 0.998 0.978,1.02 15130 23191 0.7112 0.99 0.938,1.04 1481 13393
278.1 Obesity endocrine/metabolic Both 0.7816 0.997 0.976,1.02 13507 23193 0.4027 0.988 0.96,1.02 6206 22733
278.11 Morbid obesity endocrine/metabolic Both 0.4943 0.99 0.963,1.02 6376 23143 0.4027 0.988 0.96,1.02 6206 22733
278.3 Localized adiposity endocrine/metabolic Both 0.1469 0.909 0.799,1.03 270 2694 0.177 0.914 0.803,1.04 263 2638
278.4 Abnormal weight gain endocrine/metabolic Both 0.8017 0.993 0.942,1.05 1522 13685 0.7112 0.99 0.938,1.04 1481 13393
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.008318 1.06 1.01,1.11 2245 22393 0.6683 1.02 0.927,1.13 428 4311
279.1 Immunity deficiency endocrine/metabolic Both 0.1702 1.05 0.98,1.12 881 8792 0.9016 0.991 0.865,1.14 243 2486
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.7943 0.982 0.859,1.12 254 2540 0.9016 0.991 0.865,1.14 243 2486
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.5333 0.973 0.893,1.06 574 5735 0.6776 0.982 0.9,1.07 555 5598
279.7 Other immunological findings endocrine/metabolic Both 0.1941 1.02 0.989,1.06 3927 30734 0.1714 1.02 0.99,1.06 3831 30088
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.811 1.01 0.919,1.11 443 4423 0.6683 1.02 0.927,1.13 428 4311
275.1 Disorders of iron metabolism hematopoietic Both 0.9908 0.999 0.85,1.17 168 1680 0.5188 1.09 0.845,1.4 69 689
275.11 Hereditary hemochromatosis hematopoietic Both 0.4613 1.1 0.856,1.41 70 700 0.5188 1.09 0.845,1.4 69 689
280 Iron deficiency anemias hematopoietic Both 0.5649 1.01 0.975,1.05 3537 25593 0.01698 1.07 1.01,1.13 1336 13199
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.4819 1.01 0.977,1.05 3410 25349 0.4355 1.01 0.978,1.05 3337 24805
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.01479 1.07 1.01,1.13 1361 13511 0.01698 1.07 1.01,1.13 1336 13199
281 Other deficiency anemia hematopoietic Both 0.06761 1.1 0.993,1.22 387 3838 0.4295 1.06 0.921,1.21 209 2070
281.1 Megaloblastic anemia hematopoietic Both 0.04786 1.15 1.0,1.33 189 1875 0.02291 1.22 1.03,1.44 133 1309
281.11 Pernicious anemia hematopoietic Both 0.02042 1.27 1.04,1.57 84 830 0.005495 1.34 1.09,1.66 81 815
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.03311 1.2 1.02,1.42 135 1348 0.02291 1.22 1.03,1.44 133 1309
281.9 Deficiency anemias hematopoietic Both 0.4624 1.05 0.919,1.2 214 2110 0.4295 1.06 0.921,1.21 209 2070
282 Hereditary hemolytic anemias hematopoietic Both 0.5495 1.04 0.917,1.18 248 2443 0.3184 1.09 0.921,1.29 139 1391
282.8 Other hemoglobinopathies hematopoietic Both 0.2239 1.1 0.942,1.29 158 1541 0.2173 1.1 0.943,1.29 157 1506
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.3459 1.08 0.918,1.28 143 1420 0.3184 1.09 0.921,1.29 139 1391
283 Acquired hemolytic anemias hematopoietic Both 0.811 0.977 0.811,1.18 130 1295 0.2685 0.844 0.624,1.14 52 517
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.492 0.904 0.677,1.21 54 532 0.2685 0.844 0.624,1.14 52 517
284 Aplastic anemia hematopoietic Both 0.1117 1.07 0.984,1.17 558 5545 0.1069 1.08 0.984,1.18 479 4750
284.1 Pancytopenia hematopoietic Both 0.1334 1.07 0.979,1.18 488 4847 0.1069 1.08 0.984,1.18 479 4750
285 Other anemias hematopoietic Both 0.1726 1.02 0.993,1.04 9426 28014 0.3508 1.04 0.956,1.14 540 5415
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.9616 1.0 0.961,1.04 2536 22457 0.881 1.0 0.962,1.05 2499 21995
285.2 Anemia of chronic disease hematopoietic Both 0.03715 1.06 1.0,1.11 1584 15823 0.3508 1.04 0.956,1.14 540 5415
285.21 Anemia in chronic kidney disease hematopoietic Both 0.1327 1.06 0.982,1.15 673 6722 0.1125 1.07 0.985,1.16 655 6595
285.22 Anemia in neoplastic disease hematopoietic Both 0.3926 1.04 0.953,1.13 555 5536 0.3508 1.04 0.956,1.14 540 5415
286 Coagulation defects hematopoietic Both 0.9863 1.0 0.963,1.04 3013 27144 0.4009 0.97 0.904,1.04 877 8593
286.1 Congenital coagulation defects hematopoietic Both 0.208 0.909 0.783,1.05 190 1889 0.7907 0.973 0.792,1.19 96 951
286.11 Von willebrand's disease hematopoietic Both 0.2443 0.864 0.676,1.1 64 640 0.1799 0.843 0.656,1.08 62 628
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.875 0.984 0.803,1.21 98 973 0.7907 0.973 0.792,1.19 96 951
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.8933 1.0 0.962,1.04 2601 20964 0.826 1.0 0.964,1.05 2548 20547
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.7516 1.04 0.812,1.33 60 590 0.5662 1.08 0.836,1.39 57 573
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.02884 1.17 1.02,1.35 186 1860 0.01413 1.2 1.04,1.39 180 1818
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.7762 0.969 0.781,1.2 92 906 0.9268 0.99 0.798,1.23 90 881
286.6 Defibrination syndrome hematopoietic Both 0.4365 1.02 0.973,1.07 1964 19522 0.4842 1.02 0.97,1.07 1908 19111
286.7 Other and unspecified coagulation defects hematopoietic Both 0.7943 1.01 0.964,1.05 2349 23153 0.8128 1.01 0.963,1.05 2280 22673
286.8 Hypercoagulable state hematopoietic Both 0.7211 0.985 0.908,1.07 643 6420 0.4624 0.969 0.891,1.05 598 6048
286.81 Primary hypercoagulable state hematopoietic Both 0.5164 0.973 0.896,1.06 618 6179 0.4624 0.969 0.891,1.05 598 6048
286.9 Abnormal coagulation profile hematopoietic Both 0.2692 0.961 0.896,1.03 890 8770 0.4009 0.97 0.904,1.04 877 8593
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.1795 1.03 0.987,1.07 2575 22699 0.3296 1.13 0.886,1.43 73 748
287.1 Spontaneous ecchymoses hematopoietic Both 0.4797 1.06 0.902,1.24 154 1532 0.6887 1.03 0.878,1.22 149 1500
287.3 Thrombocytopenia hematopoietic Both 0.1393 1.03 0.99,1.08 2297 20909 0.955 0.997 0.905,1.1 433 4264
287.31 Primary thrombocytopenia hematopoietic Both 0.7015 1.02 0.925,1.12 481 4785 0.881 1.01 0.914,1.11 469 4678
287.32 Secondary thrombocytopenia hematopoietic Both 0.7998 0.987 0.896,1.09 436 4360 0.955 0.997 0.905,1.1 433 4264
287.4 Qualitative platelet defects hematopoietic Both 0.1849 1.17 0.927,1.48 76 760 0.3296 1.13 0.886,1.43 73 748
288 Diseases of white blood cells hematopoietic Both 0.06607 1.03 0.998,1.07 3850 30383 0.6714 1.04 0.869,1.24 127 1251
288.1 Decreased white blood cell count hematopoietic Both 0.5395 1.02 0.961,1.08 1252 12520 0.2924 1.04 0.969,1.11 881 8781
288.11 Neutropenia hematopoietic Both 0.2748 1.04 0.97,1.11 896 8960 0.2924 1.04 0.969,1.11 881 8781
288.2 Elevated white blood cell count hematopoietic Both 0.2812 1.02 0.984,1.06 3179 28632 0.2056 1.02 0.987,1.06 3119 28121
288.3 Eosinophilia hematopoietic Both 0.7295 1.03 0.862,1.24 128 1278 0.6714 1.04 0.869,1.24 127 1251
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.6412 0.986 0.93,1.05 1259 12554 0.6266 0.97 0.857,1.1 275 2731
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.826 0.991 0.912,1.08 615 6123 0.5888 0.977 0.899,1.06 599 6006
289.4 Lymphadenitis hematopoietic Both 0.6966 1.01 0.971,1.05 3186 28420 0.8551 1.0 0.966,1.04 3013 27913
289.5 Diseases of spleen hematopoietic Both 0.3981 1.05 0.936,1.18 313 3130 0.3404 1.06 0.941,1.19 303 3075
289.8 Polycythemia, secondary hematopoietic Both 0.7413 0.975 0.84,1.13 182 1820 0.6053 0.961 0.825,1.12 176 1776
289.9 Abnormality of red blood cells hematopoietic Both 0.4966 0.958 0.847,1.08 281 2776 0.6266 0.97 0.857,1.1 275 2731
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.875 0.995 0.932,1.06 1040 9399 0.6934 0.983 0.905,1.07 630 6251
290.1 Dementias mental disorders Both 0.6486 1.02 0.924,1.14 407 3816 0.5888 0.925 0.698,1.23 53 501
290.11 Alzheimer's disease mental disorders Both 0.1057 1.18 0.966,1.43 104 984 0.1086 1.17 0.965,1.43 104 965
290.12 Dementia with cerebral degenerations mental disorders Both 0.9638 0.994 0.769,1.29 71 705 0.929 1.01 0.782,1.31 69 695
290.13 Senile dementia mental disorders Both 0.5408 1.04 0.914,1.19 257 2376 0.5902 1.04 0.909,1.18 254 2338
290.16 Vascular dementia mental disorders Both 0.5662 0.92 0.693,1.22 53 508 0.5888 0.925 0.698,1.23 53 501
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.8017 0.989 0.911,1.07 634 6242 0.7745 0.988 0.909,1.07 625 6120
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.9247 0.996 0.918,1.08 642 6369 0.6934 0.983 0.905,1.07 630 6251
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.03162 1.05 1.0,1.1 1977 19673 0.1531 1.04 0.986,1.09 1528 15170
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.2286 1.1 0.941,1.29 161 1610 0.1626 1.12 0.955,1.31 157 1566
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.4315 1.04 0.938,1.16 364 3634 0.3664 1.05 0.944,1.17 360 3552
291.8 Alteration of consciousness mental disorders Both 0.1396 1.04 0.987,1.09 1563 15497 0.1531 1.04 0.986,1.09 1528 15170
292 Neurological disorders mental disorders Both 0.02291 1.04 1.01,1.07 4340 31695 0.8551 1.02 0.858,1.2 141 1401
292.1 Aphasia/speech disturbance mental disorders Both 0.1337 1.04 0.988,1.09 1554 15459 0.7925 1.02 0.869,1.2 160 1584
292.11 Aphasia mental disorders Both 0.1521 1.07 0.977,1.16 516 5142 0.227 1.06 0.966,1.16 507 5034
292.12 Symbolic dysfunction mental disorders Both 0.7447 1.03 0.874,1.21 162 1620 0.7925 1.02 0.869,1.2 160 1584
292.2 Mild cognitive impairment mental disorders Both 0.2472 1.08 0.95,1.22 276 2716 0.2056 1.08 0.957,1.23 272 2675
292.3 Memory loss mental disorders Both 0.04365 1.06 1.0,1.12 1405 13752 0.05012 1.06 1.0,1.12 1376 13476
292.4 Altered mental status mental disorders Both 0.6808 1.01 0.963,1.06 1885 18096 0.6577 1.01 0.964,1.06 1857 17733
292.5 Transient alteration of awareness mental disorders Both 0.228 1.07 0.958,1.2 327 3237 0.1858 1.08 0.964,1.21 323 3156
292.6 Hallucinations mental disorders Both 0.955 1.0 0.848,1.19 144 1429 0.8551 1.02 0.858,1.2 141 1401
293 Symptoms involving head and neck mental disorders Both 0.5875 0.967 0.858,1.09 304 3036 0.9268 0.998 0.964,1.03 3403 31940
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.3062 1.02 0.984,1.05 3691 32427 0.9268 0.998 0.964,1.03 3403 31940
295 Schizophrenia and other psychotic disorders mental disorders Both 0.1866 1.05 0.974,1.14 664 6564 0.1023 1.08 0.985,1.18 520 5101
295.1 Schizophrenia mental disorders Both 0.5495 1.06 0.878,1.28 111 1080 0.7112 1.04 0.857,1.25 110 1057
295.2 Paranoid disorders mental disorders Both 0.8831 0.984 0.791,1.22 86 856 0.8995 0.986 0.792,1.23 84 838
295.3 Psychosis mental disorders Both 0.1365 1.07 0.979,1.17 527 5206 0.1023 1.08 0.985,1.18 520 5101
296 Mood disorders mental disorders Both 0.3837 1.01 0.987,1.03 12028 17942 0.1919 1.02 0.992,1.04 10531 17598
296.1 Bipolar mental disorders Both 0.1265 0.949 0.888,1.01 994 9331 0.1706 0.954 0.892,1.02 978 9122
296.2 Depression mental disorders Both 0.2339 1.01 0.991,1.04 11641 17941 0.1919 1.02 0.992,1.04 10531 17598
296.22 Major depressive disorder mental disorders Both 0.2897 1.01 0.989,1.04 10773 17942 0.1919 1.02 0.992,1.04 10531 17598
297 Suicidal ideation or attempt mental disorders Both 0.2056 0.95 0.878,1.03 696 6932 0.2466 0.915 0.788,1.06 200 1968
297.1 Suicidal ideation mental disorders Both 0.2679 0.952 0.872,1.04 559 5575 0.2636 0.951 0.871,1.04 552 5455
297.2 Suicide or self-inflicted injury mental disorders Both 0.2972 0.924 0.796,1.07 201 2010 0.2466 0.915 0.788,1.06 200 1968
300 Anxiety disorders mental disorders Both 0.177 1.02 0.993,1.04 12038 17949 0.4797 0.97 0.892,1.06 608 5971
300.1 Anxiety disorder mental disorders Both 0.1932 1.02 0.992,1.04 11352 17942 0.7907 1.01 0.936,1.09 717 7081
300.11 Generalized anxiety disorder mental disorders Both 0.05623 1.03 0.999,1.07 4496 17788 0.07586 1.03 0.997,1.07 4381 17445
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.02818 0.927 0.866,0.992 957 9152 0.06457 0.938 0.876,1.0 941 8937
300.13 Phobia mental disorders Both 0.6934 1.02 0.942,1.09 731 7231 0.7907 1.01 0.936,1.09 717 7081
300.3 Obsessive-compulsive disorders mental disorders Both 0.6516 1.03 0.899,1.19 223 2230 0.5957 1.04 0.904,1.19 221 2177
300.4 Dysthymic disorder mental disorders Both 0.375 1.02 0.973,1.07 1798 13630 0.2951 1.03 0.977,1.08 1763 13335
300.8 Acute reaction to stress mental disorders Both 0.8222 1.01 0.909,1.13 359 3536 0.7379 1.02 0.914,1.13 354 3453
300.9 Posttraumatic stress disorder mental disorders Both 0.4571 0.969 0.89,1.05 612 6113 0.4797 0.97 0.892,1.06 608 5971
301 Personality disorders mental disorders Both 0.3491 0.949 0.849,1.06 363 3626 0.2917 1.08 0.934,1.26 183 1824
301.2 Antisocial/borderline personality disorder mental disorders Both 0.3784 1.07 0.922,1.24 187 1868 0.2917 1.08 0.934,1.26 183 1824
302 Sexual and gender identity disorders mental disorders Both 0.1222 1.07 0.983,1.16 608 6055 0.5649 1.03 0.923,1.16 324 3168
302.1 Decreased libido mental disorders Both 0.6397 1.03 0.917,1.15 325 3233 0.5649 1.03 0.923,1.16 324 3168
303 Psychogenic and somatoform disorders mental disorders Both 0.227 1.04 0.976,1.11 1030 10064 0.09772 1.06 0.99,1.13 905 8887
303.1 Dissociative disorder mental disorders Both 0.1675 0.868 0.71,1.06 115 1144 0.241 0.887 0.725,1.08 113 1119
303.3 Psychogenic disorder mental disorders Both 0.09772 1.06 0.989,1.15 736 7330 0.8017 0.986 0.882,1.1 329 3309
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.8892 0.992 0.889,1.11 340 3376 0.8017 0.986 0.882,1.1 329 3309
303.4 Somatoform disorder mental disorders Both 0.1211 1.05 0.986,1.13 925 9106 0.09772 1.06 0.99,1.13 905 8887
304 Adjustment reaction mental disorders Both 0.4178 0.984 0.945,1.02 2840 17464 0.5984 0.989 0.95,1.03 2796 17125
305.2 Eating disorder mental disorders Both 0.5058 0.973 0.896,1.06 650 6500 0.4732 0.97 0.893,1.05 635 6327
306 Other mental disorder mental disorders Both 0.1033 0.952 0.897,1.01 1254 10907 0.6808 0.981 0.895,1.07 511 5088
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.3365 0.95 0.855,1.06 418 2847 0.3076 0.946 0.849,1.05 403 2764
306.9 Tension headache mental disorders Both 0.7447 0.985 0.9,1.08 521 5210 0.6808 0.981 0.895,1.07 511 5088
312 Conduct disorders mental disorders Both 0.8299 0.984 0.848,1.14 189 1890 0.4732 0.906 0.693,1.19 53 520
312.3 Impulse control disorder mental disorders Both 0.4529 0.902 0.689,1.18 53 530 0.4732 0.906 0.693,1.19 53 520
313 Pervasive developmental disorders mental disorders Both 0.5433 0.981 0.923,1.04 1148 11078 0.09772 1.25 0.96,1.62 59 579
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.2965 0.966 0.905,1.03 1012 9899 0.3006 0.966 0.904,1.03 1000 9693
313.2 Tics and stuttering mental disorders Both 0.1549 1.21 0.931,1.57 60 593 0.09772 1.25 0.96,1.62 59 579
315 Develomental delays and disorders mental disorders Both 0.7211 0.982 0.886,1.09 401 3990 0.3311 0.928 0.797,1.08 179 1765
315.1 Learning disorder mental disorders Both 0.3412 1.14 0.874,1.47 60 599 0.2773 1.16 0.89,1.5 59 585
315.2 Speech and language disorder mental disorders Both 0.278 0.92 0.791,1.07 182 1801 0.3311 0.928 0.797,1.08 179 1765
316 Substance addiction and disorders mental disorders Both 0.9638 0.999 0.961,1.04 2799 26014 0.6577 0.98 0.895,1.07 514 5048
316.1 Polyneuropathy due to drugs mental disorders Both 0.5129 0.97 0.887,1.06 518 5180 0.6577 0.98 0.895,1.07 514 5048
317 Alcohol-related disorders mental disorders Both 0.2032 1.03 0.984,1.08 1948 17547 0.389 1.05 0.939,1.18 332 3275
317.1 Alcoholism mental disorders Both 0.05012 1.05 1.0,1.11 1517 14733 0.389 1.05 0.939,1.18 332 3275
317.11 Alcoholic liver damage mental disorders Both 0.4169 1.05 0.937,1.17 335 3336 0.389 1.05 0.939,1.18 332 3275
318 Tobacco use disorder mental disorders Both 0.9572 1.0 0.977,1.02 9473 26924 0.8551 1.0 0.978,1.03 9286 26336
320 Meningitis neurological Both 0.9099 1.01 0.897,1.13 319 3181 0.9661 0.997 0.886,1.12 307 3112
323 Encephalitis neurological Both 0.3069 1.09 0.926,1.28 148 1475 0.3917 1.08 0.906,1.29 122 1226
323.8 Encephalitis, non-infectious neurological Both 0.3648 1.08 0.911,1.29 125 1245 0.3917 1.08 0.906,1.29 122 1226
324 Other CNS infection and poliomyelitis neurological Both 0.6577 1.03 0.905,1.17 245 2440 0.743 1.02 0.896,1.17 234 2389
327 Sleep disorders neurological Both 0.6934 0.996 0.974,1.02 11517 26652 0.863 0.976 0.738,1.29 54 542
327.1 Hypersomnia neurological Both 0.3013 1.03 0.975,1.09 1403 13919 0.2735 1.03 0.976,1.09 1380 13609
327.3 Sleep apnea neurological Both 0.3097 0.987 0.963,1.01 8293 26193 0.1652 0.98 0.954,1.01 6390 25008
327.31 Central/nonobstroctive sleep apnea neurological Both 0.6471 0.974 0.868,1.09 326 3234 0.7709 0.983 0.876,1.1 321 3182
327.32 Obstructive sleep apnea neurological Both 0.1459 0.98 0.953,1.01 6534 25537 0.1652 0.98 0.954,1.01 6390 25008
327.4 Insomnia neurological Both 0.3972 1.01 0.982,1.05 4197 25860 0.0302 1.08 1.01,1.15 865 8559
327.41 Organic or persistent insomnia neurological Both 0.03548 1.08 1.0,1.15 881 8743 0.0302 1.08 1.01,1.15 865 8559
327.5 Parasomnia neurological Both 0.4581 1.04 0.944,1.14 459 4583 0.3811 1.04 0.949,1.15 453 4493
327.6 Circadian rhythm sleep disorder neurological Both 0.3581 1.07 0.925,1.24 174 1738 0.3981 1.07 0.919,1.24 170 1693
327.7 Sleep related movement disorders neurological Both 0.455 1.02 0.966,1.08 1364 13620 0.863 0.976 0.738,1.29 54 542
327.71 Restless legs syndrome neurological Both 0.6457 1.01 0.956,1.08 1214 12132 0.4932 1.02 0.962,1.08 1188 11870
327.72 Sleep related leg cramps neurological Both 0.7852 0.962 0.728,1.27 55 550 0.863 0.976 0.738,1.29 54 542
331 Other cerebral degenerations neurological Both 0.9268 0.996 0.916,1.08 602 5935 0.8892 1.01 0.902,1.13 339 3360
331.1 Hydrocephalus neurological Both 0.6095 0.966 0.845,1.1 246 2447 0.6281 0.967 0.846,1.11 243 2394
331.9 Cerebral degeneration, unspecified neurological Both 0.6918 1.02 0.916,1.14 349 3423 0.8892 1.01 0.902,1.13 339 3360
332 Parkinson's disease neurological Both 0.9376 1.0 0.896,1.13 333 3321 0.877 1.01 0.899,1.13 328 3265
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.3048 1.02 0.979,1.07 2169 20920 0.6776 1.06 0.817,1.36 63 629
333.1 Essential tremor neurological Both 0.7447 1.01 0.93,1.11 551 5488 0.929 1.0 0.919,1.1 542 5391
333.2 Myoclonus neurological Both 0.02291 1.23 1.03,1.47 117 1160 0.02089 1.23 1.03,1.48 114 1139
333.4 Torsion dystonia neurological Both 0.04365 1.13 1.0,1.28 266 2646 0.0871 1.11 0.984,1.26 257 2601
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.6295 1.06 0.825,1.37 64 640 0.6776 1.06 0.817,1.36 63 629
334 Degenerative disease of the spinal cord neurological Both 0.04898 0.932 0.868,1.0 874 8734 0.0182 0.694 0.513,0.939 55 561
334.1 Spinocerebellar disease neurological Both 0.7194 0.954 0.737,1.23 64 631 0.6699 0.945 0.729,1.23 63 621
334.2 Anterior horn cell disease neurological Both 0.3443 0.9 0.723,1.12 92 920 0.0182 0.694 0.513,0.939 55 561
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.01549 0.691 0.513,0.932 57 570 0.0182 0.694 0.513,0.939 55 561
335 Multiple sclerosis neurological Both 0.4355 1.05 0.935,1.17 330 3284 0.537 1.04 0.925,1.16 320 3201
337 Disorders of the autonomic nervous system neurological Both 0.9886 0.999 0.914,1.09 528 5257 0.9977 1.0 0.859,1.16 183 1802
337.1 Peripheral autonomic neuropathy neurological Both 0.8531 0.986 0.847,1.15 185 1837 0.9977 1.0 0.859,1.16 183 1802
338 Pain neurological Both 0.5284 0.993 0.974,1.01 16189 22165 0.8933 0.998 0.973,1.02 8079 21630
338.1 Acute pain neurological Both 0.4955 0.992 0.971,1.01 12567 22166 0.5224 0.993 0.971,1.02 12361 21643
338.2 Chronic pain neurological Both 0.6109 0.993 0.968,1.02 8223 22154 0.8933 0.998 0.973,1.02 8079 21630
339 Other headache syndromes neurological Both 0.4581 1.01 0.985,1.03 8578 27793 0.4624 1.01 0.984,1.04 8361 27259
340 Migraine neurological Both 0.2754 1.02 0.987,1.05 5377 24263 0.9333 0.998 0.959,1.04 2788 18247
340.1 Migrain with aura neurological Both 0.9397 1.0 0.963,1.04 2862 18665 0.9333 0.998 0.959,1.04 2788 18247
341 Other demyelinating diseases of central nervous system neurological Both 0.6607 0.958 0.789,1.16 111 1105 0.8128 0.977 0.804,1.19 108 1081
342 Hemiplegia neurological Both 0.2518 1.06 0.957,1.18 360 3589 0.3206 1.06 0.948,1.18 354 3520
343 Infantile cerebral palsy neurological Both 0.114 0.812 0.628,1.05 75 750 0.1213 0.816 0.631,1.06 75 731
344 Other paralytic syndromes neurological Both 0.6039 0.977 0.896,1.07 564 5640 0.6457 0.98 0.898,1.07 554 5509
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.6124 1.01 0.967,1.06 2084 20790 0.5902 1.01 0.967,1.06 1933 19189
345.1 Epilepsy neurological Both 0.6792 0.982 0.903,1.07 607 6053 0.4624 0.963 0.871,1.06 431 4238
345.11 Generalized convulsive epilepsy neurological Both 0.8017 0.981 0.847,1.14 196 1960 0.9441 0.995 0.858,1.15 194 1913
345.12 Partial epilepsy neurological Both 0.4406 0.961 0.87,1.06 434 4333 0.4624 0.963 0.871,1.06 431 4238
345.3 Convulsions neurological Both 0.6053 1.01 0.966,1.06 1967 19598 0.5902 1.01 0.967,1.06 1933 19189
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.778 1.02 0.864,1.22 142 1404 0.7379 1.04 0.836,1.29 89 861
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.5358 0.981 0.924,1.04 1196 11927 0.5058 0.98 0.922,1.04 1164 11679
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.6934 0.956 0.763,1.2 87 860 0.7691 0.967 0.771,1.21 85 842
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.7096 1.04 0.84,1.29 90 884 0.7379 1.04 0.836,1.29 89 861
347 Cataplexy and narcolepsy neurological Both 0.3467 1.12 0.885,1.41 67 670 0.542 1.08 0.845,1.38 63 653
348 Other conditions of brain neurological Both 0.3236 1.03 0.974,1.08 1424 14226 0.4887 1.02 0.97,1.06 1951 19564
348.2 Cerebral edema and compression of brain neurological Both 0.9683 1.0 0.929,1.08 747 7463 0.7798 0.989 0.917,1.07 726 7288
348.4 Cerebral cysts neurological Both 0.7031 1.03 0.887,1.19 195 1945 0.7015 1.03 0.886,1.2 190 1906
348.7 Coma neurological Both 0.9506 0.995 0.852,1.16 162 1620 0.9908 0.999 0.856,1.17 162 1595
348.8 Encephalopathy, not elsewhere classified neurological Both 0.2547 1.05 0.967,1.14 636 6331 0.2477 1.05 0.967,1.14 627 6207
348.9 Other conditions of brain, NOS neurological Both 0.4498 1.02 0.972,1.07 2001 19979 0.4887 1.02 0.97,1.06 1951 19564
349 Other and unspecified disorders of the nervous system neurological Both 0.002951 0.891 0.826,0.961 775 7750 0.003548 0.892 0.826,0.963 763 7593
350 Abnormal movement neurological Both 0.1021 0.975 0.947,1.0 5109 32314 0.6823 0.979 0.886,1.08 435 4406
350.1 Abnormal involuntary movements neurological Both 0.389 0.982 0.942,1.02 2464 24243 0.542 0.987 0.946,1.03 2393 23735
350.2 Abnormality of gait neurological Both 0.03388 0.959 0.923,0.997 2979 25007 0.06166 0.964 0.927,1.0 2933 24488
350.3 Lack of coordination neurological Both 0.3236 0.963 0.894,1.04 773 7693 0.3027 0.961 0.891,1.04 751 7537
350.5 Abnormal reflex neurological Both 0.08913 0.856 0.716,1.02 143 1430 0.0871 0.853 0.71,1.02 138 1398
350.6 Disturbances of sensation of smell and taste neurological Both 0.7603 0.985 0.893,1.09 448 4480 0.6823 0.979 0.886,1.08 435 4406
351 Other peripheral nerve disorders neurological Both 0.6295 0.993 0.965,1.02 5685 28844 0.6266 0.993 0.964,1.02 5576 28230
352 Disorders of other cranial nerves neurological Both 0.1742 1.04 0.983,1.1 1412 14120 0.3767 1.04 0.956,1.13 618 6268
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.5902 1.03 0.931,1.13 440 4393 0.4898 1.04 0.938,1.14 431 4290
352.2 Facial nerve disorders [CN7] neurological Both 0.4111 1.03 0.954,1.12 640 6400 0.3767 1.04 0.956,1.13 618 6268
353 Nerve root and plexus disorders neurological Both 0.4498 0.986 0.951,1.02 3295 28097 0.3475 1.11 0.896,1.37 91 908
353.1 Nerve plexus lesions neurological Both 0.1271 0.911 0.807,1.03 308 3077 0.0955 0.901 0.797,1.02 300 3015
353.2 Nerve root lesions neurological Both 0.1589 1.16 0.944,1.42 94 930 0.3475 1.11 0.896,1.37 91 908
355 Complex regional/central pain syndrome neurological Both 0.5929 1.03 0.932,1.13 419 4170 0.8995 0.995 0.919,1.08 643 6368
355.1 Chronic pain syndrome neurological Both 0.8375 0.992 0.916,1.07 654 6509 0.8995 0.995 0.919,1.08 643 6368
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.4808 0.982 0.935,1.03 1728 17176 0.52 0.984 0.935,1.03 1692 16818
357 Inflammatory and toxic neuropathy neurological Both 0.9638 1.0 0.96,1.04 2467 24091 0.7211 1.01 0.966,1.05 2419 23596
358 Myoneural disorders neurological Both 0.2355 0.957 0.891,1.03 845 8441 0.4775 0.921 0.735,1.16 84 831
358.1 Myasthenia gravis neurological Both 0.4656 0.919 0.733,1.15 85 850 0.4775 0.921 0.735,1.16 84 831
359 Muscular dystrophies and other myopathies neurological Both 0.2624 1.04 0.971,1.11 868 8655 0.3428 1.03 0.964,1.11 817 8125
359.1 Muscular dystrophies neurological Both 0.7656 1.04 0.788,1.38 52 520 ,
359.2 Myopathy neurological Both 0.2897 1.04 0.968,1.11 833 8306 0.3428 1.03 0.964,1.11 817 8125
360 Disorders of the globe sense organs Both 0.3707 1.1 0.895,1.35 102 1013 0.1803 1.15 0.937,1.41 99 989
361 Retinal detachments and defects sense organs Both 0.1871 0.94 0.857,1.03 528 5265 0.6223 0.965 0.837,1.11 218 2185
361.1 Retinal detachment with retinal defect sense organs Both 0.6471 0.968 0.842,1.11 225 2226 0.6223 0.965 0.837,1.11 218 2185
362 Other retinal disorders sense organs Both 0.9528 1.0 0.96,1.04 2489 18838 0.6026 1.04 0.899,1.2 196 1957
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.3589 1.03 0.972,1.08 1529 12328 0.3126 1.03 0.972,1.09 1300 10698
362.21 Macular degeneration, dry sense organs Both 0.7852 0.984 0.874,1.11 313 2650 0.8851 0.991 0.88,1.12 307 2592
362.22 Macular degeneration, wet sense organs Both 0.2871 0.892 0.722,1.1 108 881 0.2999 0.894 0.723,1.11 107 863
362.23 Cystoid macular degeneration of retina sense organs Both 0.9419 0.995 0.879,1.13 285 2777 0.8204 0.985 0.868,1.12 278 2718
362.26 Macular puckering of retina sense organs Both 0.8472 0.992 0.913,1.08 645 6254 0.881 0.994 0.914,1.08 636 6123
362.27 Drusen (degenerative) of retina sense organs Both 0.0537 1.12 0.998,1.25 335 3205 0.0537 1.12 0.998,1.25 327 3131
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.2748 1.03 0.975,1.09 1323 10928 0.3126 1.03 0.972,1.09 1300 10698
362.3 Other nondiabetic retinopathy sense organs Both 0.743 0.986 0.909,1.07 653 6476 0.008318 0.841 0.74,0.957 289 2881
362.31 Separation of retinal layers sense organs Both 0.008913 0.844 0.744,0.958 296 2938 0.008318 0.841 0.74,0.957 289 2881
362.4 Retinal vascular changes and abnomalities sense organs Both 0.4188 0.96 0.871,1.06 449 4295 0.3828 0.957 0.866,1.06 436 4218
362.6 Peripheral retinal degenerations sense organs Both 0.526 1.04 0.92,1.18 262 2600 0.5333 1.04 0.919,1.18 260 2536
362.7 Hereditary retinal dystrophies sense organs Both 0.4853 1.07 0.888,1.28 124 1233 0.399 1.08 0.9,1.3 123 1206
362.8 Retinal hemorrhage/ischemia sense organs Both 0.1626 0.889 0.755,1.05 160 1570 0.1589 0.888 0.752,1.05 157 1533
362.9 Retinal edema sense organs Both 0.5768 1.04 0.903,1.2 202 2001 0.6026 1.04 0.899,1.2 196 1957
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.4603 1.04 0.935,1.16 375 3665 0.8054 1.02 0.89,1.16 244 2371
363.3 Chorioretinal scars sense organs Both 0.8166 1.02 0.89,1.16 249 2430 0.8054 1.02 0.89,1.16 244 2371
364 Corneal opacity and other disorders of cornea sense organs Both 0.1079 0.941 0.875,1.01 809 7919 0.9057 0.985 0.769,1.26 68 664
364.1 Corneal opacity sense organs Both 0.09772 0.903 0.8,1.02 294 2930 0.1189 0.908 0.804,1.03 292 2857
364.2 Corneal edema sense organs Both 0.8147 0.973 0.77,1.23 84 819 0.6516 0.947 0.746,1.2 82 802
364.4 Corneal degenerations sense organs Both 0.6761 1.03 0.908,1.16 274 2719 0.5333 1.04 0.918,1.18 265 2663
364.5 Corneal dystrophy sense organs Both 0.1081 0.916 0.822,1.02 377 3673 0.07079 0.869 0.746,1.01 202 1966
364.51 Fuchs' dystrophy sense organs Both 0.04898 0.86 0.74,0.999 207 2008 0.07079 0.869 0.746,1.01 202 1966
364.9 Cornea replaced by transplant sense organs Both 0.787 0.967 0.756,1.24 69 677 0.9057 0.985 0.769,1.26 68 664
365 Glaucoma sense organs Both 0.6546 0.989 0.944,1.04 1986 17152 0.7295 0.973 0.831,1.14 176 1678
365.1 Open-angle glaucoma sense organs Both 0.2158 0.943 0.859,1.03 523 4963 0.1374 0.905 0.794,1.03 273 2562
365.11 Primary open angle glaucoma sense organs Both 0.1556 0.911 0.8,1.04 281 2609 0.1374 0.905 0.794,1.03 273 2562
365.2 Primary angle-closure glaucoma sense organs Both 0.8511 0.985 0.843,1.15 179 1707 0.7295 0.973 0.831,1.14 176 1678
366 Cataract sense organs Both 0.236 1.02 0.989,1.05 6335 23476 0.07762 1.03 0.996,1.07 3753 19999
366.1 Nonsenile Cataract sense organs Both 0.6081 0.958 0.814,1.13 163 1622 0.7261 0.971 0.825,1.14 160 1580
366.2 Senile cataract sense organs Both 0.0912 1.03 0.995,1.07 3827 20410 0.07762 1.03 0.996,1.07 3753 19999
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.01288 1.03 1.01,1.06 6553 31745 0.6839 1.01 0.949,1.08 959 9458
367.1 Myopia sense organs Both 0.0537 1.03 0.999,1.07 3578 28818 0.04266 1.04 1.0,1.07 3515 28184
367.2 Astigmatism sense organs Both 0.01905 1.05 1.01,1.09 2892 26106 0.009772 1.05 1.01,1.09 2840 25525
367.4 Presbyopia sense organs Both 0.03715 1.04 1.0,1.08 3297 24582 0.0309 1.04 1.0,1.08 3231 24043
367.8 Hypermetropia sense organs Both 0.004571 1.08 1.02,1.14 1504 14729 0.004677 1.08 1.02,1.14 1480 14390
367.9 Blindness and low vision sense organs Both 0.6855 1.01 0.949,1.08 976 9663 0.6839 1.01 0.949,1.08 959 9458
368 Visual disturbances sense organs Both 0.114 1.03 0.994,1.06 4287 32818 0.03981 0.773 0.605,0.988 87 867
368.1 Amblyopia sense organs Both 0.2642 1.05 0.961,1.16 484 4830 0.413 1.04 0.947,1.14 475 4736
368.2 Diplopia and disorders of binocular vision sense organs Both 0.5636 1.02 0.951,1.1 822 8186 0.8831 1.01 0.936,1.08 797 8030
368.3 Anisometropia sense organs Both 0.2158 0.902 0.766,1.06 166 1648 0.2239 0.904 0.768,1.06 165 1626
368.4 Visual field defects sense organs Both 0.6252 1.02 0.949,1.09 879 8777 0.787 1.01 0.941,1.08 858 8593
368.9 Subjective visual disturbances sense organs Both 0.03236 1.08 1.01,1.16 829 8268 0.03981 0.773 0.605,0.988 87 867
368.91 Psychophysical visual disturbances sense organs Both 0.06918 0.799 0.628,1.02 89 885 0.03981 0.773 0.605,0.988 87 867
369 Infection of the eye sense organs Both 0.0309 1.05 1.0,1.09 2328 22262 0.04074 1.05 1.0,1.1 1924 18952
369.2 Eye infection, viral sense organs Both 0.4864 0.963 0.866,1.07 372 3688 0.507 0.964 0.866,1.07 364 3605
369.5 Conjunctivitis, infectious sense organs Both 0.03236 1.05 1.0,1.1 1974 19408 0.04074 1.05 1.0,1.1 1924 18952
370 Keratitis sense organs Both 0.5035 1.02 0.959,1.09 1051 10280 0.1854 1.12 0.949,1.31 145 1403
370.1 Corneal ulcer sense organs Both 0.5916 0.956 0.813,1.13 164 1630 0.6067 0.958 0.815,1.13 164 1589
370.2 Superficial keratitis sense organs Both 0.4498 1.04 0.939,1.15 394 3916 0.4159 1.04 0.941,1.16 387 3837
370.3 Keratoconjunctivitis sense organs Both 0.5082 1.03 0.942,1.13 531 5159 0.1854 1.12 0.949,1.31 145 1403
370.31 Keratoconjunctivitis sicca sense organs Both 0.2716 1.09 0.932,1.29 150 1432 0.1854 1.12 0.949,1.31 145 1403
371 Inflammation of the eye sense organs Both 0.07413 1.03 0.997,1.07 3269 26161 0.2443 1.13 0.92,1.39 97 950
371.1 Uveitis, noninfectious or NOS sense organs Both 0.2239 0.936 0.841,1.04 394 3892 0.1811 0.928 0.833,1.04 383 3810
371.2 Conjunctivitis, noninfectious sense organs Both 0.4305 1.03 0.954,1.12 651 6462 0.2698 1.05 0.962,1.15 516 5136
371.21 Allergic conjunctivitis sense organs Both 0.1698 1.06 0.975,1.16 532 5279 0.2698 1.05 0.962,1.15 516 5136
371.3 Inflammation of eyelids sense organs Both 0.02239 1.05 1.01,1.09 2523 21781 0.2443 1.13 0.92,1.39 97 950
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.2239 1.13 0.926,1.39 100 979 0.2443 1.13 0.92,1.39 97 950
372 Disorders of conjunctiva sense organs Both 0.005012 1.11 1.03,1.19 827 8153 0.002239 1.12 1.04,1.2 809 7990
374 Other disorders of eyelids sense organs Both 0.492 1.02 0.971,1.06 2093 18512 0.6683 1.02 0.943,1.1 747 7273
374.1 Ectropion or entropion sense organs Both 0.618 0.971 0.866,1.09 337 3251 0.7063 0.978 0.87,1.1 330 3191
374.2 Lagophthalmos sense organs Both 0.7638 0.977 0.84,1.14 192 1900 0.8395 0.984 0.845,1.15 187 1867
374.3 Ptosis of eyelid sense organs Both 0.5794 1.02 0.95,1.1 817 8140 0.4932 1.03 0.954,1.1 803 7978
374.6 Dermatochalasis sense organs Both 0.6966 1.02 0.942,1.09 759 7426 0.6683 1.02 0.943,1.1 747 7273
375 Disorders of lacrimal system sense organs Both 0.002042 1.06 1.02,1.11 2683 21054 0.1002 1.1 0.983,1.22 345 3464
375.1 Dry eyes sense organs Both 0.01047 1.05 1.01,1.09 2966 21823 0.007586 1.05 1.01,1.1 2898 21335
375.2 Epiphora sense organs Both 0.1 1.09 0.983,1.22 356 3540 0.1002 1.1 0.983,1.22 345 3464
376 Disorders of the orbit sense organs Both 0.6683 0.974 0.863,1.1 285 2814 0.8531 0.989 0.875,1.12 278 2752
377 Disorders of optic nerve and visual pathways sense organs Both 0.2065 1.05 0.973,1.13 706 7010 0.375 1.04 0.95,1.15 454 4526
377.1 Optic atrophy sense organs Both 0.1941 1.1 0.953,1.27 200 1997 0.1875 1.1 0.954,1.27 198 1947
377.3 Optic neuritis/neuropathy sense organs Both 0.3467 1.05 0.953,1.15 468 4627 0.375 1.04 0.95,1.15 454 4526
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.9638 0.998 0.934,1.07 969 9602 0.2472 0.929 0.819,1.05 268 2669
378.1 Strabismus (not specified as paralytic) sense organs Both 0.778 1.01 0.931,1.1 617 6131 0.9908 1.0 0.918,1.09 600 6011
378.2 Nystagmus and other irregular eye movements sense organs Both 0.1 1.15 0.974,1.35 138 1371 0.07079 1.16 0.988,1.37 136 1342
378.5 Paralytic strabismus sense organs Both 0.25 0.93 0.821,1.05 275 2720 0.2472 0.929 0.819,1.05 268 2669
379 Other disorders of eye sense organs Both 0.877 0.997 0.962,1.03 3593 24835 0.5636 0.979 0.913,1.05 844 8405
379.1 Scleritis and episcleritis sense organs Both 0.3334 0.919 0.774,1.09 140 1379 0.2938 0.91 0.762,1.09 132 1346
379.2 Disorders of vitreous body sense organs Both 0.4519 1.02 0.975,1.06 2559 18709 0.3639 1.02 0.978,1.06 2505 18351
379.3 Aphakia and other disorders of lens sense organs Both 0.5585 1.07 0.859,1.32 87 838 0.4932 1.08 0.868,1.34 85 823
379.4 Anomalies of pupillary function sense organs Both 0.2704 0.926 0.807,1.06 231 2303 0.2838 0.927 0.808,1.06 228 2252
379.5 Disorders of iris and ciliary body sense organs Both 0.912 0.992 0.863,1.14 215 2128 0.1288 1.21 0.945,1.56 61 593
379.51 Pigmentary iris degeneration sense organs Both 0.1288 1.21 0.945,1.56 61 610 0.1288 1.21 0.945,1.56 61 593
379.9 Pain, swelling or discharge of eye sense organs Both 0.7244 0.988 0.921,1.06 870 8594 0.5636 0.979 0.913,1.05 844 8405
380 Disorders of external ear sense organs Both 0.05012 1.05 1.0,1.11 1634 15553 0.1489 1.03 0.988,1.08 1951 18264
380.1 Otitis externa sense organs Both 0.001318 1.1 1.04,1.17 1124 11213 0.005248 1.09 1.03,1.16 1097 10988
380.4 Impacted cerumen sense organs Both 0.1449 1.03 0.988,1.08 1985 18630 0.1489 1.03 0.988,1.08 1951 18264
381 Otitis media and Eustachian tube disorders sense organs Both 0.02291 1.04 1.01,1.08 3291 29339 0.5902 1.03 0.917,1.16 289 2894
381.1 Otitis media sense organs Both 0.1256 1.03 0.991,1.08 2402 23549 0.1556 1.03 0.988,1.08 2006 19707
381.11 Suppurative and unspecified otitis media sense organs Both 0.13 1.04 0.99,1.08 2037 20175 0.1556 1.03 0.988,1.08 2006 19707
381.2 Eustachian tube disorders sense organs Both 0.08511 1.05 0.993,1.11 1393 13815 0.1807 1.04 0.983,1.1 1360 13499
381.3 Mastoiditis & related conditions sense organs Both 0.9016 1.01 0.843,1.21 126 1260 0.8375 1.02 0.849,1.22 125 1233
381.9 Otorrhea sense organs Both 0.3758 1.05 0.938,1.19 297 2960 0.5902 1.03 0.917,1.16 289 2894
382 Otalgia sense organs Both 0.002754 1.08 1.03,1.14 1425 14188 0.003467 1.08 1.03,1.14 1397 13828
383 Otosclerosis sense organs Both 1.0 1.0 0.818,1.22 112 1120 0.7691 1.03 0.843,1.26 111 1095
384 Other disorders of tympanic membrane sense organs Both 0.3639 1.05 0.947,1.16 397 3962 0.6266 1.03 0.915,1.16 313 3127
384.4 Perforation of tympanic membrane sense organs Both 0.5047 1.04 0.925,1.17 318 3180 0.6266 1.03 0.915,1.16 313 3127
385 Other disorders of middle ear and mastoid sense organs Both 0.7295 0.981 0.878,1.1 358 3580 0.2512 1.12 0.92,1.37 101 1007
385.3 Cholesteatoma sense organs Both 0.4592 0.949 0.827,1.09 245 2450 0.5117 0.955 0.833,1.1 242 2393
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.26 1.12 0.92,1.36 103 1025 0.2512 1.12 0.92,1.37 101 1007
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.8318 1.01 0.953,1.06 1441 14255 0.3214 0.985 0.956,1.01 5194 30942
386.1 Meniere's disease sense organs Both 0.7031 0.975 0.853,1.11 248 2464 0.8954 0.991 0.866,1.13 239 2416
386.2 Peripheral or central vertigo sense organs Both 0.9795 0.999 0.942,1.06 1209 11971 0.5689 1.02 0.952,1.09 871 8560
386.21 Central origin vertigo sense organs Both 0.7047 1.01 0.946,1.09 883 8759 0.5689 1.02 0.952,1.09 871 8560
386.3 Labyrinthitis sense organs Both 0.5152 1.02 0.959,1.09 1099 10904 0.4064 1.03 0.965,1.09 1082 10649
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.3475 0.986 0.958,1.02 5315 31605 0.3214 0.985 0.956,1.01 5194 30942
388 Other disorders of ear sense organs Both 0.1524 1.06 0.98,1.14 699 6960 0.1795 1.05 0.976,1.14 678 6800
389 Hearing loss sense organs Both 0.08128 1.02 0.997,1.05 6285 31750 0.9931 0.999 0.807,1.24 99 982
389.1 Sensorineural hearing loss sense organs Both 0.9484 0.999 0.962,1.04 3130 24231 0.9204 0.998 0.961,1.04 3061 23742
389.2 Conductive hearing loss sense organs Both 0.4074 0.968 0.896,1.05 717 7169 0.507 0.974 0.902,1.05 706 7022
389.3 Degenerative and vascular disorders of ear sense organs Both 0.1954 1.12 0.943,1.33 143 1338 0.1637 1.13 0.951,1.35 141 1305
389.4 Tinnitus sense organs Both 0.2917 1.03 0.977,1.08 1677 16701 0.2871 1.03 0.977,1.08 1646 16360
389.5 Disorders of acoustic nerve sense organs Both 0.8185 0.976 0.789,1.21 101 1010 0.9931 0.999 0.807,1.24 99 982
394 Rheumatic disease of the heart valves circulatory system Both 0.4055 1.03 0.966,1.09 1177 11253 0.1648 1.07 0.973,1.17 458 4539
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.8472 0.988 0.876,1.12 284 2766 0.877 0.99 0.876,1.12 275 2728
394.2 Mitral valve disease circulatory system Both 0.7447 1.02 0.915,1.13 378 3735 0.9462 1.0 0.9,1.12 364 3660
394.3 Aortic valve disease circulatory system Both 0.6281 1.04 0.882,1.23 150 1465 0.5662 1.05 0.889,1.24 149 1446
394.7 Disease of tricuspid valve circulatory system Both 0.2123 1.06 0.967,1.17 468 4624 0.1648 1.07 0.973,1.17 458 4539
395 Heart valve disorders circulatory system Both 0.01288 1.05 1.01,1.09 3169 23926 0.3784 1.03 0.963,1.11 866 8069
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.04467 1.05 1.0,1.1 1754 16787 0.09772 1.04 0.992,1.09 1717 16440
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.3491 1.02 0.974,1.08 1619 13932 0.3715 1.02 0.972,1.08 1593 13681
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.01585 1.14 1.02,1.26 373 3704 0.02399 1.13 1.02,1.25 363 3641
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.8974 0.986 0.789,1.23 84 831 0.7907 0.97 0.776,1.21 83 817
395.6 Heart valve replaced circulatory system Both 0.3396 1.03 0.965,1.11 878 8213 0.3784 1.03 0.963,1.11 866 8069
396 Abnormal heart sounds circulatory system Both 0.02818 1.04 1.0,1.07 3754 28453 0.03467 1.04 1.0,1.07 3667 27842
401 Hypertension circulatory system Both 0.6124 1.01 0.983,1.03 18784 19071 0.3467 1.02 0.976,1.07 1971 12730
401.1 Essential hypertension circulatory system Both 0.6516 1.01 0.983,1.03 18655 19070 0.5957 1.01 0.983,1.03 18243 18696
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.3141 1.02 0.979,1.07 2599 12045 0.1102 1.04 0.991,1.09 1975 10723
401.21 Hypertensive heart disease circulatory system Both 0.2958 1.05 0.96,1.14 556 4628 0.2618 1.05 0.963,1.15 544 4554
401.22 Hypertensive chronic kidney disease circulatory system Both 0.1837 1.03 0.985,1.08 2015 10909 0.1102 1.04 0.991,1.09 1975 10723
401.3 Other hypertensive complications circulatory system Both 0.2158 1.03 0.983,1.08 2027 12961 0.3467 1.02 0.976,1.07 1971 12730
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.1159 1.04 0.991,1.08 2132 15248 0.1014 1.04 0.993,1.09 2083 14943
411 Ischemic Heart Disease circulatory system Both 0.5176 1.01 0.981,1.04 6970 25468 0.3873 1.05 0.94,1.17 329 3194
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.2333 1.05 0.97,1.13 702 6842 0.1816 1.05 0.976,1.14 689 6717
411.2 Myocardial infarction circulatory system Both 0.1358 1.03 0.99,1.07 2849 17983 0.1309 1.03 0.991,1.07 2807 17621
411.3 Angina pectoris circulatory system Both 0.8511 1.0 0.958,1.05 1904 15218 0.8204 1.01 0.958,1.06 1872 14928
411.4 Coronary atherosclerosis circulatory system Both 0.6012 1.01 0.978,1.04 5938 22890 0.5585 0.946 0.786,1.14 116 1131
411.41 Aneurysm and dissection of heart circulatory system Both 0.5 0.938 0.779,1.13 117 1149 0.5585 0.946 0.786,1.14 116 1131
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.5728 1.01 0.977,1.04 4877 21174 0.5649 1.01 0.977,1.04 4799 20725
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.4753 1.04 0.932,1.16 335 3247 0.3873 1.05 0.94,1.17 329 3194
414 Other forms of chronic heart disease circulatory system Both 0.1288 1.03 0.99,1.08 2360 18485 0.4775 1.03 0.943,1.13 476 4764
414.2 ASCVD circulatory system Both 0.5035 1.03 0.942,1.13 492 4846 0.4775 1.03 0.943,1.13 476 4764
415 Pulmonary heart disease circulatory system Both 0.4721 1.01 0.975,1.06 2726 25061 0.4365 1.03 0.95,1.13 578 5791
415.1 Acute pulmonary heart disease circulatory system Both 0.5662 1.02 0.964,1.07 1510 15045 0.5521 1.02 0.964,1.07 1468 14705
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.5861 1.01 0.963,1.07 1507 15014 0.5521 1.02 0.964,1.07 1468 14705
415.2 Chronic pulmonary heart disease circulatory system Both 0.4266 1.02 0.969,1.08 1506 14839 0.4365 1.03 0.95,1.13 578 5791
415.21 Primary pulmonary hypertension circulatory system Both 0.6607 1.02 0.936,1.11 592 5901 0.4365 1.03 0.95,1.13 578 5791
416 Cardiomegaly circulatory system Both 0.2239 1.04 0.975,1.11 935 9293 0.1585 1.05 0.981,1.12 917 9112
418 Nonspecific chest pain circulatory system Both 0.005495 1.03 1.01,1.06 10015 28233 0.7499 1.01 0.951,1.07 1162 11571
418.1 Precordial pain circulatory system Both 0.7762 1.01 0.95,1.07 1193 11816 0.7499 1.01 0.951,1.07 1162 11571
420 Carditis circulatory system Both 0.04571 1.06 1.0,1.12 1275 12633 0.5248 1.03 0.944,1.12 592 5882
420.1 Myocarditis circulatory system Both 0.3819 0.9 0.711,1.14 76 752 0.5105 0.924 0.73,1.17 75 736
420.2 Pericarditis circulatory system Both 0.01175 1.1 1.02,1.19 684 6830 0.1374 1.16 0.954,1.41 90 897
420.21 Acute pericarditis circulatory system Both 0.3266 0.916 0.768,1.09 144 1435 0.4276 0.931 0.781,1.11 140 1402
420.22 Chronic pericarditis circulatory system Both 0.2113 1.13 0.932,1.38 92 912 0.1374 1.16 0.954,1.41 90 897
420.3 Endocarditis circulatory system Both 0.6252 1.02 0.939,1.11 602 5990 0.5248 1.03 0.944,1.12 592 5882
425 Cardiomyopathy circulatory system Both 0.5943 1.01 0.964,1.07 1617 15758 0.02951 1.29 1.03,1.61 70 694
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.7311 1.01 0.958,1.06 1557 15170 0.5236 0.947 0.802,1.12 153 1499
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.7047 0.97 0.829,1.14 171 1699 0.6607 0.965 0.823,1.13 169 1672
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.4603 0.939 0.796,1.11 154 1540 0.5236 0.947 0.802,1.12 153 1499
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.4385 1.05 0.926,1.19 248 2480 0.4365 1.05 0.926,1.19 244 2424
425.8 Other cardiomyopathy circulatory system Both 0.04571 1.26 1.0,1.58 71 709 0.02951 1.29 1.03,1.61 70 694
426 Cardiac conduction disorders circulatory system Both 0.09772 1.02 0.996,1.05 9881 21221 0.8128 1.01 0.93,1.1 619 5612
426.2 Atrioventricular [AV] block circulatory system Both 0.4864 1.02 0.965,1.08 1527 9610 0.09333 1.15 0.978,1.35 158 1465
426.21 First degree AV block circulatory system Both 0.631 1.02 0.953,1.08 1064 7510 0.7745 1.01 0.946,1.08 1043 7374
426.22 Mobitz II AV block circulatory system Both 0.7998 1.03 0.799,1.34 56 513 0.7447 1.04 0.807,1.35 55 510
426.23 Second degree AV block circulatory system Both 0.4775 1.06 0.905,1.24 161 1459 0.4315 1.07 0.91,1.25 157 1437
426.24 Atrioventricular block, complete circulatory system Both 0.9977 1.0 0.896,1.12 357 3041 0.8892 0.992 0.888,1.11 350 2992
426.25 Other heart block circulatory system Both 0.07079 1.16 0.988,1.36 161 1489 0.09333 1.15 0.978,1.35 158 1465
426.3 Bundle branch block circulatory system Both 0.7194 0.991 0.942,1.04 1775 11373 0.52 0.975 0.901,1.05 712 6117
426.31 Right bundle branch block circulatory system Both 0.8892 0.996 0.935,1.06 1101 8763 0.6252 0.984 0.924,1.05 1079 8610
426.32 Left bundle branch block circulatory system Both 0.5176 0.975 0.902,1.05 721 6217 0.52 0.975 0.901,1.05 712 6117
426.4 Anomalous atrioventricular excitation circulatory system Both 0.5082 1.08 0.852,1.38 62 611 0.4656 1.09 0.86,1.39 62 599
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.07413 1.02 0.998,1.05 8452 21094 0.08511 1.02 0.997,1.05 8248 20666
426.8 Other cardiac conduction disorders circulatory system Both 0.05495 1.09 0.998,1.2 456 4529 0.04365 1.1 1.0,1.21 449 4455
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.2518 1.04 0.976,1.1 1261 8802 0.8128 1.01 0.93,1.1 619 5612
426.91 Cardiac pacemaker in situ circulatory system Both 0.4426 1.03 0.957,1.11 836 6124 0.4487 1.03 0.956,1.11 824 6022
426.92 Cardiac defibrillator in situ circulatory system Both 0.7516 1.01 0.934,1.1 628 5698 0.8128 1.01 0.93,1.1 619 5612
427 Cardiac dysrhythmias circulatory system Both 0.3327 1.01 0.989,1.03 14018 21321 0.03162 1.04 1.0,1.08 3331 19735
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.1396 1.04 0.988,1.09 1882 14769 0.7482 1.01 0.944,1.08 877 7840
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.195 1.04 0.98,1.1 1193 11216 0.1738 1.04 0.982,1.11 1167 10980
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.6124 1.02 0.951,1.09 892 7975 0.7482 1.01 0.944,1.08 877 7840
427.2 Atrial fibrillation and flutter circulatory system Both 0.3228 1.02 0.982,1.06 4194 15493 0.4217 1.02 0.969,1.08 1577 9508
427.21 Atrial fibrillation circulatory system Both 0.5321 1.01 0.975,1.05 4097 15312 0.5623 1.01 0.974,1.05 4021 15013
427.22 Atrial flutter circulatory system Both 0.4365 1.02 0.968,1.08 1598 9674 0.4217 1.02 0.969,1.08 1577 9508
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.7943 1.0 0.976,1.03 7129 21276 0.857 1.0 0.975,1.03 6977 20848
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.2104 1.06 0.965,1.17 419 4137 0.6039 1.03 0.921,1.15 314 3136
427.41 Ventricular fibrillation and flutter circulatory system Both 0.05495 1.16 0.997,1.35 167 1670 0.05495 1.16 0.997,1.35 165 1642
427.42 Cardiac arrest circulatory system Both 0.6457 1.03 0.918,1.15 321 3186 0.6039 1.03 0.921,1.15 314 3136
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.4236 1.01 0.982,1.04 5521 21271 0.5521 1.01 0.979,1.04 5401 20842
427.6 Premature beats circulatory system Both 0.4539 1.02 0.97,1.07 1820 13218 0.5495 1.03 0.939,1.13 513 4787
427.61 Supraventricular premature beats circulatory system Both 0.5495 1.03 0.94,1.12 522 4879 0.5495 1.03 0.939,1.13 513 4787
427.7 Tachycardia NOS circulatory system Both 0.2168 1.02 0.988,1.06 3980 21286 0.1607 1.02 0.99,1.06 3884 20857
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.5585 1.02 0.949,1.1 738 6224 0.6792 1.02 0.942,1.1 723 6132
427.9 Palpitations circulatory system Both 0.03311 1.04 1.0,1.08 3420 20157 0.03162 1.04 1.0,1.08 3331 19735
428 Congestive heart failure; nonhypertensive circulatory system Both 0.0871 1.03 0.995,1.07 3326 19946 0.5433 1.02 0.959,1.08 1187 10432
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.06166 1.04 0.998,1.08 2965 19130 0.03981 1.04 1.0,1.08 2916 18762
428.2 Heart failure NOS circulatory system Both 0.241 1.02 0.984,1.07 2781 17962 0.1879 1.03 0.987,1.07 2735 17627
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.354 1.03 0.97,1.09 1288 11396 0.3673 1.03 0.969,1.09 1268 11209
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.6637 1.01 0.955,1.08 1208 10616 0.5433 1.02 0.959,1.08 1187 10432
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.2748 1.01 0.989,1.04 9394 27581 0.007943 1.12 1.03,1.21 582 5721
429.1 Heart transplant/surgery circulatory system Both 0.01202 1.09 1.02,1.17 823 8070 0.01413 1.09 1.02,1.17 808 7940
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.1352 1.03 0.992,1.06 4445 23965 0.156 1.02 0.991,1.06 4344 23474
429.3 Symptoms involving cardiovascular system circulatory system Both 0.3076 1.01 0.987,1.04 7147 27443 0.3112 1.01 0.987,1.04 6974 26884
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.01023 1.11 1.03,1.21 591 5816 0.007943 1.12 1.03,1.21 582 5721
430 Intracranial hemorrhage circulatory system Both 0.2818 0.956 0.879,1.04 633 6305 0.9795 0.998 0.863,1.15 199 1987
430.1 Subarachnoid hemorrhage circulatory system Both 0.4742 0.95 0.827,1.09 230 2300 0.5848 0.962 0.836,1.11 228 2240
430.2 Intracerebral hemorrhage circulatory system Both 0.5916 0.968 0.861,1.09 314 3132 0.4909 0.959 0.851,1.08 309 3085
430.3 Subdural hemorrhage circulatory system Both 0.9183 1.01 0.872,1.16 202 2017 0.9795 0.998 0.863,1.15 199 1987
433 Cerebrovascular disease circulatory system Both 0.1991 1.02 0.989,1.06 4361 26660 0.5309 1.03 0.942,1.12 525 5178
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.877 1.0 0.952,1.06 1533 12978 0.07762 1.24 0.976,1.59 60 588
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.2153 1.1 0.948,1.27 188 1858 0.2061 1.1 0.949,1.27 185 1818
433.12 Cerebral atherosclerosis circulatory system Both 0.08511 1.24 0.971,1.58 61 599 0.07762 1.24 0.976,1.59 60 588
433.2 Occlusion of cerebral arteries circulatory system Both 0.542 0.985 0.94,1.03 1926 17593 0.7145 0.991 0.944,1.04 1825 16677
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.8072 0.994 0.947,1.04 1862 17011 0.7145 0.991 0.944,1.04 1825 16677
433.3 Cerebral ischemia circulatory system Both 0.004169 1.07 1.02,1.12 2122 18040 0.04467 1.05 1.0,1.1 1775 15746
433.31 Transient cerebral ischemia circulatory system Both 0.04074 1.05 1.0,1.1 1812 16062 0.04467 1.05 1.0,1.1 1775 15746
433.5 Cerebral aneurysm circulatory system Both 0.1483 0.926 0.833,1.03 408 4070 0.1346 0.922 0.829,1.03 398 3973
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.04266 1.11 1.0,1.23 383 3803 0.05248 1.11 0.999,1.23 375 3735
433.8 Late effects of cerebrovascular disease circulatory system Both 0.5346 1.03 0.943,1.12 534 5286 0.5309 1.03 0.942,1.12 525 5178
440 Atherosclerosis circulatory system Both 0.07413 1.04 0.996,1.09 1946 16499 0.02455 1.09 1.01,1.18 689 6684
440.1 Atherosclerosis of renal artery circulatory system Both 0.8831 1.01 0.871,1.17 187 1855 0.9204 1.01 0.866,1.17 181 1818
440.2 Atherosclerosis of the extremities circulatory system Both 0.08318 1.05 0.993,1.12 1166 11265 0.02291 1.09 1.01,1.17 802 7833
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.1698 0.896 0.766,1.05 183 1815 0.1858 0.899 0.768,1.05 182 1790
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.01259 1.1 1.02,1.18 812 7979 0.02291 1.09 1.01,1.17 802 7833
440.9 Atherosclerosis of aorta circulatory system Both 0.02089 1.1 1.01,1.18 702 6800 0.02455 1.09 1.01,1.18 689 6684
441 Vascular insufficiency of intestine circulatory system Both 0.912 0.994 0.898,1.1 407 4039 0.6124 0.951 0.784,1.15 119 1186
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.9183 1.01 0.875,1.16 206 2025 0.9462 1.0 0.872,1.16 204 1985
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.6412 0.956 0.789,1.16 122 1207 0.6124 0.951 0.784,1.15 119 1186
442 Other aneurysm circulatory system Both 0.5358 1.01 0.971,1.06 2309 18098 0.4688 0.957 0.851,1.08 319 3238
442.1 Aortic aneurysm circulatory system Both 0.6839 1.01 0.961,1.06 1703 13812 0.6792 0.986 0.923,1.05 976 8864
442.11 Abdominal aortic aneurysm circulatory system Both 0.6982 0.987 0.925,1.05 992 9021 0.6792 0.986 0.923,1.05 976 8864
442.2 Aneurysm of iliac artery circulatory system Both 0.4932 1.05 0.905,1.23 177 1769 0.4819 1.06 0.906,1.23 175 1736
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.00912 1.25 1.06,1.48 137 1357 0.007943 1.26 1.06,1.49 135 1337
442.4 Arterial dissection circulatory system Both 0.975 1.0 0.855,1.18 156 1555 0.975 0.998 0.849,1.17 151 1521
442.8 Aneurysm of other specified artery circulatory system Both 0.4529 0.956 0.851,1.07 330 3300 0.4688 0.957 0.851,1.08 319 3238
443 Peripheral vascular disease circulatory system Both 0.9638 1.0 0.959,1.04 2355 20353 0.6339 1.01 0.963,1.06 1717 14863
443.1 Raynaud's syndrome circulatory system Both 0.8035 0.989 0.91,1.08 608 6051 0.8453 0.992 0.911,1.08 596 5895
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.1807 0.88 0.73,1.06 141 1375 0.2489 0.896 0.743,1.08 140 1349
443.8 Other specified peripheral vascular diseases circulatory system Both 0.9727 1.0 0.954,1.05 1899 17476 0.9397 1.0 0.955,1.05 1872 17112
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.5702 1.01 0.965,1.07 1747 15154 0.6339 1.01 0.963,1.06 1717 14863
444 Arterial embolism and thrombosis circulatory system Both 0.826 1.01 0.931,1.09 675 6732 0.5781 0.949 0.789,1.14 127 1262
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.4656 1.05 0.92,1.2 240 2392 0.4102 1.06 0.926,1.21 237 2354
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.6067 0.953 0.794,1.14 129 1282 0.5781 0.949 0.789,1.14 127 1262
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.3899 1.05 0.942,1.16 367 3641 0.2858 1.07 0.941,1.23 225 2231
446.4 Wegener's granulomatosis circulatory system Both 0.1923 1.15 0.932,1.42 86 857 0.1928 1.15 0.932,1.42 85 843
446.5 Giant cell arteritis circulatory system Both 0.2163 0.841 0.639,1.11 59 547 0.2051 0.837 0.635,1.1 58 540
446.9 Arteritis NOS circulatory system Both 0.3119 1.07 0.938,1.22 230 2285 0.2858 1.07 0.941,1.23 225 2231
447 Other disorders of arteries and arterioles circulatory system Both 0.2692 1.03 0.981,1.07 2116 18819 0.8147 1.01 0.931,1.1 620 6201
447.1 Stricture of artery circulatory system Both 0.4786 0.965 0.873,1.07 435 4322 0.4276 0.96 0.869,1.06 429 4245
447.7 Aortic ectasia circulatory system Both 0.5546 1.02 0.945,1.11 637 6315 0.8147 1.01 0.931,1.1 620 6201
448 Disease of capillaries circulatory system Both 0.7112 1.01 0.945,1.09 853 8472 0.7727 1.01 0.942,1.08 831 8286
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.2415 0.97 0.923,1.02 1701 17006 0.25 0.971 0.922,1.02 1654 16610
451 Phlebitis and thrombophlebitis circulatory system Both 0.2786 1.05 0.963,1.14 582 5764 0.04571 1.16 1.0,1.34 185 1854
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.0871 1.14 0.982,1.32 190 1888 0.04571 1.16 1.0,1.34 185 1854
452 Other venous embolism and thrombosis circulatory system Both 0.6471 1.01 0.974,1.04 3773 25068 0.861 1.02 0.849,1.22 118 1156
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.08511 0.887 0.774,1.02 228 2277 0.1191 0.897 0.782,1.03 223 2226
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.5521 1.01 0.972,1.05 2623 22444 0.4217 1.02 0.976,1.06 2560 21972
452.8 Postphlebitic syndrome circulatory system Both 0.9954 0.999 0.835,1.2 119 1181 0.861 1.02 0.849,1.22 118 1156
453 Chronic venous hypertension circulatory system Both 0.9661 0.997 0.851,1.17 173 1715 0.9162 0.991 0.844,1.16 169 1675
454 Varicose veins circulatory system Both 0.6516 1.01 0.967,1.06 2206 20243 0.5728 0.983 0.924,1.04 1157 11499
454.1 Varicose veins of lower extremity circulatory system Both 0.8433 1.0 0.958,1.05 1908 17574 0.5728 0.983 0.924,1.04 1157 11499
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.673 0.987 0.929,1.05 1182 11754 0.5728 0.983 0.924,1.04 1157 11499
455 Hemorrhoids circulatory system Both 0.4111 1.01 0.981,1.05 4379 24588 0.4295 1.01 0.981,1.05 4288 24059
456 Chronic venous insufficiency [CVI] circulatory system Both 0.317 1.02 0.979,1.07 2303 20367 0.4018 1.02 0.975,1.06 2250 19923
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.6982 0.991 0.944,1.04 1946 14131 0.9886 1.0 0.952,1.05 1812 13403
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.8974 0.992 0.88,1.12 287 2845 0.881 0.991 0.879,1.12 284 2802
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.7568 0.992 0.945,1.04 1841 13661 0.9886 1.0 0.952,1.05 1812 13403
458 Hypotension circulatory system Both 0.3069 1.02 0.984,1.05 4073 28546 0.2099 1.02 0.987,1.06 3571 26872
458.1 Orthostatic hypotension circulatory system Both 0.2559 1.04 0.974,1.11 1031 10176 0.2582 1.04 0.973,1.11 1003 9969
458.2 Iatrogenic hypotension circulatory system Both 0.9057 0.996 0.929,1.07 911 9084 0.929 1.0 0.936,1.08 898 8906
458.9 Hypotension NOS circulatory system Both 0.2661 1.02 0.985,1.06 3641 27465 0.2099 1.02 0.987,1.06 3571 26872
459 Other disorders of circulatory system circulatory system Both 0.06761 1.03 0.998,1.07 3553 27674 0.1416 1.03 0.99,1.07 2703 23179
459.1 Hemorrhage NOS circulatory system Both 0.5284 1.03 0.946,1.11 619 6159 0.4797 1.03 0.949,1.12 609 6041
459.7 Blood vessel replaced circulatory system Both 0.02239 1.17 1.02,1.35 203 2030 0.02344 1.17 1.02,1.35 199 1998
459.9 Circulatory disease NEC circulatory system Both 0.09772 1.03 0.994,1.08 2757 23656 0.1416 1.03 0.99,1.07 2703 23179
464 Acute sinusitis respiratory Both 0.1067 1.03 0.994,1.06 3675 26562 0.1002 1.03 0.994,1.07 3610 25980
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.2084 1.02 0.991,1.04 7223 30143 0.1552 1.08 0.971,1.21 336 3349
465.2 Acute pharyngitis respiratory Both 0.113 1.03 0.994,1.06 3967 26715 0.08128 1.03 0.996,1.07 3894 26116
465.4 Acute laryngitis and tracheitis respiratory Both 0.2158 1.07 0.961,1.19 345 3441 0.1552 1.08 0.971,1.21 336 3349
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.6653 1.01 0.959,1.07 1431 14130 0.5358 1.02 0.963,1.07 1410 13848
471 Nasal polyps respiratory Both 0.7568 1.01 0.924,1.11 475 4727 0.8185 1.01 0.92,1.11 466 4645
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.1766 1.04 0.983,1.1 1344 13251 0.1675 1.04 0.984,1.1 1317 12968
473 Diseases of the larynx and vocal cords respiratory Both 1.0 1.0 0.958,1.04 2393 20985 0.6252 0.988 0.941,1.04 1785 17708
473.1 Chronic laryngitis respiratory Both 0.1262 0.798 0.598,1.07 57 562 0.1358 0.803 0.602,1.07 57 548
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.2582 1.05 0.962,1.15 517 5167 0.5741 1.03 0.933,1.13 448 5073
473.4 Voice disturbance respiratory Both 0.9772 0.999 0.953,1.05 1880 18033 0.6252 0.988 0.941,1.04 1785 17708
474 Acute and chronic tonsillitis respiratory Both 0.04074 1.08 1.0,1.17 685 6193 0.01318 1.11 1.02,1.21 544 5073
474.1 Acute tonsillitis respiratory Both 0.4446 1.05 0.929,1.18 267 2507 0.3311 1.06 0.94,1.2 265 2459
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.01995 1.1 1.02,1.2 555 5166 0.01318 1.11 1.02,1.21 544 5073
475 Chronic sinusitis respiratory Both 0.007413 1.05 1.01,1.09 3434 23149 0.1099 1.07 0.985,1.16 640 6308
475.9 Postnasal drip respiratory Both 0.1521 1.06 0.979,1.15 651 6441 0.1099 1.07 0.985,1.16 640 6308
476 Allergic rhinitis respiratory Both 0.005623 1.03 1.01,1.06 10205 23354 0.004571 1.03 1.01,1.06 9957 22933
477 Epistaxis or throat hemorrhage respiratory Both 0.2455 1.04 0.973,1.11 895 8841 0.2138 1.04 0.975,1.12 878 8678
478 Throat pain respiratory Both 0.743 1.02 0.91,1.14 325 3233 0.7586 1.02 0.908,1.14 317 3171
479 Other upper respiratory disease respiratory Both 0.002344 1.05 1.02,1.08 4428 23338 0.002884 1.05 1.02,1.08 4327 22917
480 Pneumonia respiratory Both 8.318E-4 1.05 1.02,1.08 4823 30881 0.02754 1.21 1.02,1.44 115 1149
480.1 Bacterial pneumonia respiratory Both 0.09772 1.06 0.989,1.14 860 8567 0.9268 1.01 0.809,1.26 80 802
480.11 Pneumococcal pneumonia respiratory Both 0.04571 1.11 1.0,1.23 372 3720 0.09333 1.09 0.985,1.21 367 3644
480.12 Pseudomonal pneumonia respiratory Both 0.3656 0.916 0.757,1.11 121 1192 0.2917 0.902 0.744,1.09 118 1167
480.13 MRSA pneumonia respiratory Both 0.9016 1.01 0.813,1.26 82 818 0.9268 1.01 0.809,1.26 80 802
480.2 Viral pneumonia respiratory Both 0.1045 1.15 0.971,1.36 147 1461 0.1355 1.14 0.96,1.35 143 1439
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.8035 0.977 0.812,1.17 117 1170 0.8472 0.982 0.817,1.18 117 1147
480.5 Bronchopneumonia and lung abscess respiratory Both 0.01905 1.23 1.03,1.45 119 1175 0.02754 1.21 1.02,1.44 115 1149
481 Influenza respiratory Both 0.01778 1.08 1.01,1.15 990 9863 0.009772 1.09 1.02,1.16 971 9645
483 Acute bronchitis and bronchiolitis respiratory Both 0.5943 1.01 0.971,1.05 2615 24227 0.4831 1.01 0.974,1.06 2556 23688
495 Asthma respiratory Both 0.175 1.02 0.992,1.05 6951 27725 0.227 1.04 0.978,1.1 1220 12150
495.1 Chronic obstructive asthma respiratory Both 0.4276 1.05 0.936,1.17 341 3403 0.05754 1.28 0.992,1.64 60 575
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.07413 1.25 0.978,1.59 60 592 0.05754 1.28 0.992,1.64 60 575
495.2 Asthma with exacerbation respiratory Both 0.1919 1.04 0.981,1.1 1251 12442 0.227 1.04 0.978,1.1 1220 12150
496 Chronic airway obstruction respiratory Both 0.3793 1.01 0.982,1.05 4444 23893 0.3459 1.05 0.95,1.16 427 4238
496.1 Emphysema respiratory Both 0.3767 1.02 0.974,1.07 1831 16712 0.3972 1.02 0.973,1.07 1801 16397
496.2 Chronic bronchitis respiratory Both 0.5888 1.01 0.974,1.05 3357 22668 0.5808 1.01 0.973,1.05 2989 21262
496.21 Obstructive chronic bronchitis respiratory Both 0.6339 1.01 0.971,1.05 3040 21701 0.5808 1.01 0.973,1.05 2989 21262
496.3 Bronchiectasis respiratory Both 0.456 1.04 0.942,1.14 435 4329 0.3459 1.05 0.95,1.16 427 4238
497 Bronchitis respiratory Both 0.8241 1.01 0.953,1.06 1481 14700 0.6486 1.01 0.959,1.07 1450 14382
498 Acute bronchospasm respiratory Both 0.9977 1.0 0.899,1.11 376 3745 0.975 1.0 0.9,1.12 368 3653
499 Cystic fibrosis respiratory Both 0.7962 1.02 0.857,1.22 116 1160 0.8054 1.02 0.855,1.22 112 1129
500 Lung disease due to external agents respiratory Both 0.7674 1.01 0.921,1.12 428 4273 0.4677 0.91 0.705,1.17 64 633
500.1 Extrinsic allergic alveolitis respiratory Both 0.3724 0.894 0.7,1.14 81 810 0.3622 0.891 0.695,1.14 78 788
500.2 Pneumoconiosis respiratory Both 0.4355 0.904 0.7,1.17 65 640 0.4677 0.91 0.705,1.17 64 633
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.7345 1.02 0.928,1.11 514 5078 0.8166 1.01 0.923,1.11 499 4975
502 Postinflammatory pulmonary fibrosis respiratory Both 0.6095 1.02 0.941,1.11 623 6192 0.4169 1.03 0.953,1.12 609 6070
503 Pulmonary congestion and hypostasis respiratory Both 0.7638 0.988 0.912,1.07 690 6875 0.7925 0.989 0.913,1.07 682 6750
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.743 1.02 0.923,1.12 447 4454 0.5297 1.04 0.917,1.18 246 2413
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.6266 1.03 0.908,1.17 247 2456 0.5297 1.04 0.917,1.18 246 2413
505 Other pulmonary inflamation or edema respiratory Both 0.4634 1.02 0.966,1.08 1352 13261 0.4645 1.02 0.965,1.08 1325 13013
506 Empyema and pneumothorax respiratory Both 0.6501 1.01 0.969,1.05 2588 22332 0.8017 1.01 0.965,1.05 2529 21927
507 Pleurisy; pleural effusion respiratory Both 0.3681 1.02 0.978,1.06 2415 21828 0.3436 1.02 0.978,1.06 2355 21397
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.7047 1.01 0.964,1.06 2005 19256 0.7551 1.01 0.962,1.06 1956 18899
509 Respiratory failure, insufficiency, arrest respiratory Both 0.1816 1.03 0.988,1.07 3044 23898 0.354 0.966 0.899,1.04 833 8313
509.1 Respiratory failure respiratory Both 0.3373 1.03 0.973,1.08 1466 14560 0.309 1.03 0.974,1.09 1446 14303
509.2 Respiratory insufficiency respiratory Both 0.1112 1.06 0.988,1.13 928 9238 0.1086 1.06 0.988,1.13 915 9070
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.1 1.04 0.992,1.1 1500 14783 0.08511 1.05 0.994,1.1 1476 14521
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.2339 0.957 0.891,1.03 848 8472 0.354 0.966 0.899,1.04 833 8313
510 Other diseases of lung respiratory Both 9.772E-4 1.05 1.02,1.09 4671 30168 0.9376 1.01 0.837,1.21 125 1255
510.2 Lung transplant respiratory Both 0.7129 1.03 0.862,1.24 128 1274 0.9376 1.01 0.837,1.21 125 1255
512 Other symptoms of respiratory system respiratory Both 0.125 1.02 0.995,1.04 14878 23476 0.1096 1.02 0.995,1.05 8464 22991
512.1 Wheezing respiratory Both 0.05129 1.06 1.0,1.13 1071 10626 0.0537 1.06 0.999,1.13 1039 10398
512.2 Painful respiration respiratory Both 0.05623 1.05 0.999,1.1 1765 17029 0.02291 1.06 1.01,1.11 1714 16655
512.3 Abnormal chest sounds respiratory Both 0.0537 1.14 0.998,1.31 229 2261 0.03631 1.16 1.01,1.32 224 2219
512.7 Shortness of breath respiratory Both 0.0912 1.02 0.996,1.05 7928 23452 0.07079 1.02 0.998,1.05 7742 22976
512.8 Cough respiratory Both 0.1135 1.02 0.995,1.05 7280 23469 0.06918 1.03 0.998,1.05 7134 22993
512.9 Other dyspnea respiratory Both 0.1094 1.02 0.995,1.05 8658 23467 0.1096 1.02 0.995,1.05 8464 22991
513 Respiratory abnormalities respiratory Both 0.01585 1.03 1.01,1.05 10231 28110 0.375 0.935 0.807,1.08 202 2020
513.3 Hypoventilation respiratory Both 0.2858 1.05 0.963,1.13 618 6146 0.04571 1.17 1.0,1.36 161 1628
513.31 Apnea respiratory Both 0.6471 1.03 0.915,1.15 314 3136 0.6668 1.03 0.913,1.15 306 3078
513.32 Orthopnea respiratory Both 0.06457 1.15 0.991,1.34 167 1662 0.04571 1.17 1.0,1.36 161 1628
513.4 Hyperventilation respiratory Both 0.4966 1.03 0.938,1.14 440 4383 0.4064 1.04 0.945,1.15 430 4294
513.8 Disorders of diaphragm respiratory Both 0.4943 0.95 0.821,1.1 206 2053 0.375 0.935 0.807,1.08 202 2020
514 Abnormal findings examination of lungs respiratory Both 0.01259 1.04 1.01,1.07 4486 29229 0.01862 1.05 1.01,1.1 2410 22254
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.07413 1.14 0.987,1.32 193 1914 0.07244 1.14 0.988,1.32 189 1884
514.2 Solitary pulmonary nodule respiratory Both 0.00631 1.06 1.02,1.1 2489 22668 0.01862 1.05 1.01,1.1 2410 22254
516 Abnormal sputum respiratory Both 0.4645 1.03 0.948,1.12 565 5640 0.3105 1.05 0.956,1.15 458 4633
516.1 Hemoptysis respiratory Both 0.309 1.05 0.957,1.15 473 4720 0.3105 1.05 0.956,1.15 458 4633
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.2415 1.02 0.988,1.05 5153 32053 0.6887 1.01 0.974,1.04 3942 28613
519.1 Tracheostomy complications respiratory Both 0.4498 1.06 0.912,1.23 176 1760 0.5794 1.04 0.896,1.22 168 1721
519.2 Respiratory complications respiratory Both 0.263 1.06 0.956,1.18 370 3696 0.4688 1.04 0.935,1.16 362 3645
519.8 Other diseases of respiratory system, NEC respiratory Both 0.006918 1.1 1.03,1.17 887 8857 0.01549 1.09 1.02,1.17 862 8682
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.695 1.01 0.974,1.04 4043 29199 0.6887 1.01 0.974,1.04 3942 28613
520 Disorders of tooth development digestive Both 0.6966 0.977 0.866,1.1 291 2900 0.526 0.951 0.815,1.11 172 1659
520.1 Hereditary disturbances in tooth structure digestive Both 0.8299 1.02 0.854,1.22 131 1301 0.7345 1.03 0.862,1.24 127 1274
520.2 Disturbances in tooth eruption digestive Both 0.4436 0.941 0.806,1.1 172 1693 0.526 0.951 0.815,1.11 172 1659
521 Diseases of hard tissues of teeth digestive Both 0.7447 1.01 0.939,1.09 719 7167 0.7278 1.01 0.937,1.1 660 6570
521.1 Dental caries digestive Both 0.826 1.01 0.933,1.09 673 6709 0.7278 1.01 0.937,1.1 660 6570
522 Diseases of pulp and periapical tissues digestive Both 0.9908 1.0 0.903,1.11 408 4067 0.6622 0.975 0.87,1.09 334 3327
522.5 Periapical abscess digestive Both 0.5929 0.97 0.866,1.09 341 3404 0.6622 0.975 0.87,1.09 334 3327
523 Gingival and periodontal diseases digestive Both 0.8204 1.01 0.927,1.1 569 5690 0.7534 0.968 0.789,1.19 102 1013
523.1 Gingivitis digestive Both 0.9397 0.992 0.814,1.21 117 1163 0.7962 0.974 0.798,1.19 115 1141
523.3 Periodontitis (acute or chronic) digestive Both 0.7889 0.984 0.874,1.11 294 2940 0.7534 0.968 0.789,1.19 102 1013
523.31 Acute periodontitis digestive Both 0.8356 1.01 0.892,1.15 251 2510 0.5521 1.04 0.915,1.18 246 2450
523.32 Chronic periodontitis digestive Both 0.8299 0.978 0.798,1.2 103 1030 0.7534 0.968 0.789,1.19 102 1013
524 Dentofacial anomalies, including malocclusion digestive Both 0.5572 1.04 0.922,1.16 308 3080 0.1766 1.11 0.955,1.28 185 1811
524.3 Anomalies of tooth position/malocclusion digestive Both 0.1837 1.11 0.954,1.28 186 1856 0.1766 1.11 0.955,1.28 185 1811
525 Other diseases of the teeth and supporting structures digestive Both 0.743 0.988 0.921,1.06 853 8530 0.3097 0.941 0.837,1.06 313 3105
525.1 Loss of teeth or edentulism digestive Both 0.3357 0.945 0.841,1.06 318 3178 0.3097 0.941 0.837,1.06 313 3105
526 Diseases of the jaws digestive Both 0.9462 1.0 0.958,1.05 2140 21162 0.1161 0.917 0.824,1.02 391 3893
526.1 Cysts of the jaws digestive Both 0.8337 1.01 0.884,1.17 213 2123 0.7211 1.03 0.893,1.18 211 2077
526.3 Anomalies of jaw size/symmetry digestive Both 0.6982 0.971 0.838,1.13 206 2052 0.6871 0.97 0.836,1.12 204 2011
526.4 Temporomandibular joint disorders digestive Both 0.01995 1.07 1.01,1.14 1178 11779 0.02399 1.1 1.01,1.19 591 5839
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.1057 1.06 0.989,1.13 941 9410 0.07586 1.06 0.994,1.13 927 9180
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.05012 1.09 1.0,1.18 600 5993 0.02399 1.1 1.01,1.19 591 5839
526.5 Inflammatory conditions of jaw digestive Both 0.007244 0.827 0.719,0.95 242 2405 0.00912 0.831 0.723,0.955 241 2360
526.9 Jaw disease NOS digestive Both 0.1081 0.916 0.824,1.02 399 3982 0.1161 0.917 0.824,1.02 391 3893
527 Diseases of the salivary glands digestive Both 0.984 0.999 0.945,1.06 1362 13604 0.3105 0.923 0.789,1.08 187 1918
527.2 Sialoadenitis digestive Both 0.6109 1.03 0.919,1.15 320 3200 0.52 1.04 0.924,1.17 293 3130
527.7 Disturbance of salivary secretion digestive Both 0.6668 0.983 0.911,1.06 715 7141 0.8017 0.99 0.915,1.07 678 6996
527.8 Other specified diseases of the salivary glands digestive Both 0.4345 0.941 0.809,1.1 196 1960 0.3105 0.923 0.789,1.08 187 1918
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.6442 1.01 0.966,1.06 2077 20750 0.798 1.02 0.853,1.23 129 1290
528.1 Stomatitis and mucositis digestive Both 0.1656 1.06 0.975,1.16 536 5360 0.7295 1.03 0.882,1.2 167 1666
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.06457 1.16 0.991,1.35 165 1650 0.06607 1.16 0.991,1.35 163 1600
528.12 Oral aphthae digestive Both 0.6998 1.03 0.886,1.2 170 1700 0.7295 1.03 0.882,1.2 167 1666
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.1127 1.13 0.972,1.31 185 1837 0.1403 1.12 0.964,1.3 182 1800
528.4 Cysts of oral soft tissues digestive Both 0.8185 0.977 0.804,1.19 110 1096 0.2642 1.14 0.904,1.44 66 660
528.41 Cyst of the salivary gland digestive Both 0.2979 1.13 0.896,1.43 68 679 0.2642 1.14 0.904,1.44 66 660
528.5 Diseases of lips digestive Both 0.7244 1.02 0.912,1.14 334 3340 0.7656 1.02 0.908,1.14 327 3279
528.6 Leukoplakia of oral mucosa digestive Both 0.9705 0.996 0.828,1.2 113 1120 0.867 0.984 0.817,1.19 112 1098
528.7 Sialolithiasis digestive Both 0.9376 0.993 0.828,1.19 132 1320 0.798 1.02 0.853,1.23 129 1290
529 Diseases and other conditions of the tongue digestive Both 0.1396 1.07 0.979,1.16 541 5402 0.929 1.01 0.845,1.2 135 1335
529.1 Glossitis digestive Both 0.4966 1.07 0.877,1.31 99 982 0.5649 1.06 0.866,1.3 98 963
529.6 Glossodynia digestive Both 0.9462 1.01 0.844,1.2 136 1355 0.929 1.01 0.845,1.2 135 1335
530 Diseases of esophagus digestive Both 0.1059 1.02 0.996,1.04 13874 23034 0.02455 1.07 1.01,1.14 1171 11714
530.1 Esophagitis, GERD and related diseases digestive Both 0.1247 1.02 0.995,1.04 13419 23031 0.863 0.985 0.83,1.17 140 1405
530.11 GERD digestive Both 0.1982 1.01 0.993,1.04 13059 23031 0.2307 1.01 0.991,1.04 12750 22611
530.12 Ulcer of esophagus digestive Both 0.5675 1.04 0.92,1.16 298 2973 0.4786 1.04 0.927,1.18 293 2919
530.13 Barrett's esophagus digestive Both 0.4285 1.03 0.952,1.12 609 6080 0.5834 1.02 0.942,1.11 597 5976
530.14 Reflux esophagitis digestive Both 0.4498 1.02 0.968,1.08 1483 14213 0.5176 1.02 0.964,1.07 1439 13945
530.15 Eosinophilic esophagitis digestive Both 0.7834 0.977 0.824,1.16 145 1441 0.863 0.985 0.83,1.17 140 1405
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.02692 1.11 1.01,1.22 475 4742 0.04266 1.1 1.0,1.21 467 4662
530.3 Stricture and stenosis of esophagus digestive Both 0.2618 1.04 0.969,1.12 752 7474 0.3342 1.04 0.962,1.12 719 7337
530.5 Disorders of esophageal motility digestive Both 0.929 1.0 0.91,1.11 434 4326 0.8892 1.01 0.912,1.11 423 4248
530.6 Diverticulum of esophagus, acquired digestive Both 0.03162 1.22 1.02,1.47 121 1181 0.03631 1.22 1.01,1.47 119 1161
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.8395 0.975 0.767,1.24 70 700 0.9333 0.99 0.776,1.26 70 681
530.9 Heartburn digestive Both 0.02951 1.07 1.01,1.13 1198 11946 0.02455 1.07 1.01,1.14 1171 11714
531 Peptic ulcer (excl. esophageal) digestive Both 0.01148 1.07 1.01,1.12 1608 16066 0.5984 1.06 0.863,1.29 115 1107
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.05495 1.12 0.998,1.25 311 3103 0.0537 1.12 0.998,1.25 308 3043
531.2 Gastric ulcer digestive Both 0.08128 1.06 0.993,1.14 884 8834 0.1197 1.06 0.986,1.13 864 8652
531.3 Duodenal ulcer digestive Both 0.8395 1.01 0.91,1.12 362 3613 0.7998 1.01 0.911,1.13 355 3546
531.4 Peptic ulcer, site unspecified digestive Both 0.02818 1.09 1.01,1.19 632 6313 0.05754 1.08 0.997,1.17 616 6168
531.5 Gastrojejunal ulcer digestive Both 0.6486 1.05 0.856,1.28 115 1143 0.5984 1.06 0.863,1.29 115 1107
532 Dysphagia digestive Both 0.3273 1.02 0.984,1.05 4457 22190 0.561 1.01 0.977,1.04 4314 21778
535 Gastritis and duodenitis digestive Both 0.1361 1.03 0.99,1.08 2129 21208 0.01905 1.08 1.01,1.15 955 9603
535.1 Acute gastritis digestive Both 0.1521 1.05 0.981,1.13 814 8139 0.2037 1.05 0.975,1.13 792 7975
535.2 Atrophic gastritis digestive Both 0.6982 1.03 0.901,1.17 250 2500 0.6383 1.03 0.904,1.18 240 2435
535.6 Duodenitis digestive Both 0.4276 0.95 0.836,1.08 265 2650 0.5395 0.961 0.845,1.09 261 2600
535.8 Other specified gastritis digestive Both 0.03631 1.1 1.01,1.2 497 4964 0.02754 1.11 1.01,1.21 488 4851
535.9 Gastritis and duodenitis, NOS digestive Both 0.02089 1.08 1.01,1.15 985 9835 0.01905 1.08 1.01,1.15 955 9603
536 Disorders of function of stomach digestive Both 0.6871 1.01 0.966,1.05 2251 22311 0.4159 1.02 0.971,1.07 1652 16478
536.3 Gastroparesis digestive Both 0.03631 0.902 0.819,0.994 489 4876 0.0912 0.919 0.834,1.01 476 4752
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.0955 1.1 0.984,1.23 334 3331 0.08318 1.1 0.987,1.23 328 3258
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.4667 1.02 0.969,1.07 1699 16834 0.4159 1.02 0.971,1.07 1652 16478
537 Other disorders of stomach and duodenum digestive Both 0.2698 1.02 0.982,1.07 2357 23199 0.4634 1.07 0.893,1.28 125 1248
537.1 Lesions of stomach and duodenum digestive Both 0.5572 1.06 0.882,1.26 128 1271 0.4634 1.07 0.893,1.28 125 1248
539 Bariatric surgery digestive Both 0.1409 0.954 0.896,1.02 1118 11180 0.2296 0.962 0.903,1.02 1096 10875
540 Appendiceal conditions digestive Both 0.08511 1.09 0.988,1.21 399 3990 0.07244 1.12 0.99,1.26 287 2867
540.1 Appendicitis digestive Both 0.08511 1.1 0.987,1.23 349 3490 0.07244 1.12 0.99,1.26 287 2867
540.11 Acute appendicitis digestive Both 0.07586 1.11 0.989,1.25 293 2930 0.07244 1.12 0.99,1.26 287 2867
550 Abdominal hernia digestive Both 0.5408 1.01 0.98,1.04 5517 31191 0.133 0.952 0.894,1.01 1078 10745
550.1 Inguinal hernia digestive Both 0.7129 0.99 0.937,1.05 1427 13556 0.5984 0.985 0.932,1.04 1405 13313
550.2 Diaphragmatic hernia digestive Both 0.236 1.03 0.983,1.07 2290 21266 0.4121 1.02 0.975,1.06 2238 20796
550.3 Femoral hernia digestive Both 0.2606 0.892 0.731,1.09 109 1082 0.3048 0.901 0.738,1.1 108 1056
550.4 Umbilical hernia digestive Both 0.9772 1.0 0.94,1.07 1053 10514 0.9078 1.0 0.942,1.07 1039 10280
550.5 Ventral hernia digestive Both 0.9247 1.0 0.955,1.05 1826 18190 0.8318 1.01 0.958,1.06 1797 17794
550.6 Incisional hernia digestive Both 0.1047 0.949 0.891,1.01 1101 10999 0.133 0.952 0.894,1.01 1078 10745
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.02239 1.07 1.01,1.13 1275 12527 0.03548 1.11 1.01,1.22 433 4269
555.1 Regional enteritis digestive Both 0.01585 1.09 1.02,1.17 775 7701 0.01549 1.09 1.02,1.18 766 7532
555.2 Ulcerative colitis digestive Both 0.0631 1.07 0.996,1.15 768 7591 0.03548 1.11 1.01,1.22 433 4269
555.21 Ulcerative colitis (chronic) digestive Both 0.04467 1.1 1.0,1.21 438 4361 0.03548 1.11 1.01,1.22 433 4269
556 Ulceration of the lower GI tract digestive Both 0.1968 1.06 0.969,1.16 473 4719 0.02344 1.21 1.03,1.42 144 1465
556.1 Ulceration of intestine digestive Both 0.09772 1.09 0.985,1.2 412 4099 0.02344 1.21 1.03,1.42 144 1465
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.02089 1.21 1.03,1.41 152 1496 0.02344 1.21 1.03,1.42 144 1465
557 Intestinal malabsorption (non-celiac) digestive Both 0.8511 1.01 0.95,1.06 1306 12565 0.7816 1.02 0.904,1.14 299 2962
557.1 Celiac disease digestive Both 0.9016 1.01 0.896,1.13 305 3050 0.7816 1.02 0.904,1.14 299 2962
558 Noninfectious gastroenteritis digestive Both 0.1786 1.03 0.988,1.07 2706 20417 0.1762 1.03 0.988,1.07 2641 19964
559 Ileostomy status digestive Both 0.1227 1.06 0.985,1.14 773 7702 0.1112 1.06 0.987,1.14 767 7543
560 Intestinal obstruction without mention of hernia digestive Both 0.2911 0.978 0.938,1.02 2580 20303 0.9419 0.998 0.946,1.05 1467 14059
560.1 Paralytic ileus digestive Both 0.2685 0.97 0.918,1.02 1429 13524 0.3999 0.977 0.924,1.03 1413 13247
560.2 Impaction of intestine digestive Both 0.6653 1.03 0.905,1.17 257 2499 0.52 1.04 0.918,1.18 255 2426
560.3 Peritoneal or intestinal adhesions digestive Both 0.1334 0.906 0.796,1.03 261 2599 0.1455 0.908 0.797,1.03 257 2545
560.4 Other intestinal obstruction digestive Both 0.7603 0.992 0.94,1.05 1489 14381 0.9419 0.998 0.946,1.05 1467 14059
561 Symptoms involving digestive system digestive Both 0.04365 1.03 1.0,1.05 7750 22039 0.02089 1.05 1.01,1.1 2307 18555
561.1 Diarrhea digestive Both 0.05248 1.03 1.0,1.06 5986 22042 0.03802 1.03 1.0,1.06 5841 21566
561.2 Flatulence digestive Both 0.04898 1.04 1.0,1.09 2358 18995 0.02089 1.05 1.01,1.1 2307 18555
562 Diverticulosis and diverticulitis digestive Both 0.03548 1.03 1.0,1.07 5014 18500 0.1954 1.04 0.981,1.1 1258 11966
562.1 Diverticulosis digestive Both 0.03548 1.03 1.0,1.07 4973 18448 0.03162 1.04 1.0,1.07 4872 18040
562.2 Diverticulitis digestive Both 0.175 1.04 0.983,1.1 1292 12242 0.1954 1.04 0.981,1.1 1258 11966
563 Constipation digestive Both 0.5943 1.01 0.979,1.04 5639 22004 0.3945 1.01 0.983,1.04 5525 21529
564 Functional digestive disorders digestive Both 0.6209 1.01 0.982,1.03 9553 22037 0.1611 1.04 0.986,1.09 1722 16137
564.1 Irritable Bowel Syndrome digestive Both 0.8222 1.0 0.965,1.05 2751 17147 0.7943 1.01 0.965,1.05 2681 16737
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.6383 0.99 0.948,1.03 2348 18710 0.7015 0.992 0.949,1.04 2302 18300
564.9 Personal history of diseases of digestive system digestive Both 0.1675 1.03 0.986,1.09 1762 16521 0.1611 1.04 0.986,1.09 1722 16137
565 Anal and rectal conditions digestive Both 0.02754 1.05 1.01,1.09 2533 24500 0.06457 1.06 0.996,1.14 913 9116
565.1 Anal and rectal polyp digestive Both 0.05248 1.07 0.999,1.14 932 9300 0.06457 1.06 0.996,1.14 913 9116
567 Peritonitis and retroperitoneal infections digestive Both 0.7656 1.01 0.95,1.07 1149 11482 0.6823 1.01 0.953,1.08 1138 11227
568 Other disorders of peritoneum digestive Both 0.3981 0.977 0.925,1.03 1452 14494 0.1603 0.955 0.896,1.02 1065 10526
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.1242 0.951 0.892,1.01 1076 10752 0.1603 0.955 0.896,1.02 1065 10526
569 Other disorders of intestine digestive Both 0.01148 1.04 1.01,1.06 6343 29512 0.7586 1.01 0.951,1.07 1191 11817
569.1 Toxic gastroenteritis and colitis digestive Both 0.2825 1.07 0.944,1.22 251 2510 0.2748 1.07 0.945,1.22 247 2457
569.2 Gastrointestinal complications digestive Both 0.778 1.01 0.951,1.07 1206 12058 0.7586 1.01 0.951,1.07 1191 11817
571 Chronic liver disease and cirrhosis digestive Both 0.3076 1.02 0.983,1.05 3603 27394 0.3681 1.04 0.95,1.15 437 4309
571.5 Other chronic nonalcoholic liver disease digestive Both 0.1954 1.02 0.988,1.06 3388 27100 0.5023 1.03 0.953,1.1 767 7638
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.4909 1.03 0.954,1.1 781 7802 0.5023 1.03 0.953,1.1 767 7638
571.6 Primary biliary cirrhosis digestive Both 0.6561 1.04 0.878,1.23 146 1460 0.6067 1.04 0.884,1.23 146 1421
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.3597 1.04 0.961,1.12 749 7472 0.3681 1.04 0.95,1.15 437 4309
571.81 Portal hypertension digestive Both 0.4064 1.04 0.946,1.15 441 4400 0.3681 1.04 0.95,1.15 437 4309
572 Ascites (non malignant) digestive Both 0.2812 1.03 0.979,1.08 1884 18805 0.2259 1.03 0.982,1.08 1858 18391
573 Other disorders of liver digestive Both 0.4102 1.01 0.982,1.05 4460 28151 0.05012 1.04 1.0,1.07 3279 27448
573.1 Chronic passive congestion of liver digestive Both 0.2884 1.12 0.908,1.38 100 991 0.241 1.13 0.919,1.4 97 978
573.2 Liver replaced by transplant digestive Both 0.08511 1.12 0.984,1.28 227 2268 0.1112 1.11 0.975,1.27 223 2224
573.3 Hepatomegaly digestive Both 0.07244 0.899 0.801,1.01 337 3368 0.1086 0.908 0.808,1.02 326 3288
573.4 Acute and subacute necrosis of liver digestive Both 0.182 1.09 0.962,1.23 258 2580 0.13 1.1 0.972,1.24 255 2525
573.5 Jaundice (not of newborn) digestive Both 0.0871 1.07 0.991,1.15 758 7555 0.06918 1.07 0.995,1.15 750 7405
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.1239 1.04 0.99,1.09 1973 19683 0.09772 1.04 0.993,1.09 1937 19261
573.7 Abnormal results of function study of liver digestive Both 0.002512 1.07 1.02,1.12 2110 21014 0.00263 1.07 1.02,1.12 2063 20575
573.9 Abnormal serum enzyme levels digestive Both 0.0871 1.03 0.995,1.07 3345 28043 0.05012 1.04 1.0,1.07 3279 27448
574 Cholelithiasis and cholecystitis digestive Both 0.8375 1.0 0.965,1.05 2610 25589 0.2323 1.05 0.969,1.14 656 6499
574.1 Cholelithiasis digestive Both 0.7482 1.01 0.966,1.05 2391 23829 0.3199 1.05 0.953,1.16 443 4339
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.6823 0.974 0.858,1.11 260 2580 0.8072 0.984 0.867,1.12 256 2514
574.12 Cholelithiasis with other cholecystitis digestive Both 0.3698 1.05 0.949,1.15 444 4434 0.3199 1.05 0.953,1.16 443 4339
574.2 Calculus of bile duct digestive Both 0.9572 1.0 0.927,1.08 696 6939 0.9506 0.998 0.922,1.08 683 6782
574.3 Cholecystitis without cholelithiasis digestive Both 0.3041 1.04 0.963,1.13 667 6662 0.2323 1.05 0.969,1.14 656 6499
575 Other biliary tract disease digestive Both 0.5495 1.01 0.968,1.06 1868 18668 0.06607 0.867 0.744,1.01 185 1845
575.1 Cholangitis digestive Both 0.1109 1.1 0.979,1.23 310 3089 0.1007 1.1 0.982,1.23 306 3028
575.2 Obstruction of bile duct digestive Both 0.3055 0.954 0.872,1.04 530 5291 0.3055 0.954 0.871,1.04 522 5188
575.6 Cholesterolosis of gallbladder digestive Both 0.06026 1.16 0.993,1.35 168 1680 0.06607 1.16 0.99,1.35 164 1644
575.7 Other disorders of gallbladder digestive Both 0.5495 1.02 0.95,1.1 773 7719 0.3828 1.03 0.959,1.11 756 7532
575.8 Other disorders of biliary tract digestive Both 0.9183 0.997 0.934,1.06 996 9950 0.8913 1.0 0.942,1.07 984 9735
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.05754 0.862 0.74,1.0 188 1880 0.06607 0.867 0.744,1.01 185 1845
577 Diseases of pancreas digestive Both 0.5794 1.01 0.966,1.06 1842 18379 0.139 1.07 0.977,1.18 452 4461
577.1 Acute pancreatitis digestive Both 0.1172 1.05 0.987,1.12 967 9651 0.0912 1.06 0.991,1.13 954 9429
577.2 Chronic pancreatitis digestive Both 0.5297 1.03 0.933,1.14 396 3955 0.4246 1.04 0.942,1.15 391 3864
577.3 Cyst and pseudocyst of pancreas digestive Both 0.139 1.07 0.977,1.18 462 4557 0.139 1.07 0.977,1.18 452 4461
578 Gastrointestinal hemorrhage digestive Both 0.134 1.03 0.992,1.06 3572 30460 0.1089 1.05 0.989,1.11 1211 12022
578.1 Hematemesis digestive Both 0.05888 1.1 0.997,1.22 383 3821 0.06026 1.1 0.996,1.22 377 3733
578.2 Blood in stool digestive Both 0.2985 1.02 0.98,1.07 2156 21196 0.3846 1.02 0.976,1.07 2115 20729
578.8 Hemorrhage of rectum and anus digestive Both 0.05623 1.05 0.999,1.1 1718 17070 0.0537 1.05 0.999,1.1 1688 16676
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.0955 1.05 0.992,1.11 1238 12280 0.1089 1.05 0.989,1.11 1211 12022
579 Other symptoms involving abdomen and pelvis digestive Both 0.4898 0.988 0.955,1.02 3750 28690 0.05623 1.07 0.998,1.14 981 9662
579.2 Splenomegaly digestive Both 0.7586 1.01 0.932,1.1 593 5923 0.8035 1.01 0.929,1.1 585 5813
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.0955 1.06 0.99,1.13 998 9882 0.05623 1.07 0.998,1.14 981 9662
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.1648 1.04 0.983,1.1 1264 12626 0.1387 1.1 0.97,1.24 267 2698
580.1 Glomerulonephritis genitourinary Both 0.5445 1.04 0.925,1.16 324 3228 0.3048 1.07 0.938,1.23 224 2249
580.11 Proliferative glomerulonephritis genitourinary Both 0.3155 0.906 0.748,1.1 114 1140 0.1663 0.87 0.714,1.06 111 1119
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.861 0.981 0.792,1.22 92 905 0.7551 0.966 0.778,1.2 90 884
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.1614 1.1 0.963,1.25 232 2298 0.3048 1.07 0.938,1.23 224 2249
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.5834 1.04 0.894,1.22 167 1670 0.8356 1.02 0.868,1.19 164 1639
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.7112 1.01 0.947,1.08 943 9430 0.7962 1.01 0.922,1.11 486 4878
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.5794 1.03 0.939,1.12 554 5535 0.4436 1.03 0.948,1.13 545 5414
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.6577 1.02 0.931,1.12 500 4995 0.7962 1.01 0.922,1.11 486 4878
580.4 Renal sclerosis, NOS genitourinary Both 0.1445 1.09 0.969,1.24 275 2750 0.1387 1.1 0.97,1.24 267 2698
585 Renal failure genitourinary Both 0.5164 1.01 0.981,1.04 5756 27307 0.02754 1.08 1.01,1.16 837 8230
585.1 Acute renal failure genitourinary Both 0.8204 1.0 0.968,1.04 3278 22851 0.6324 1.01 0.972,1.05 3216 22396
585.2 Renal failure NOS genitourinary Both 0.006761 1.11 1.03,1.2 688 6872 0.005012 1.12 1.03,1.21 678 6740
585.3 Chronic renal failure [CKD] genitourinary Both 0.3192 1.02 0.984,1.05 4216 24655 0.07244 1.07 0.993,1.16 688 6908
585.31 Renal dialysis genitourinary Both 0.1596 1.07 0.975,1.16 543 5430 0.1236 1.07 0.981,1.17 533 5335
585.32 End stage renal disease genitourinary Both 0.526 1.02 0.951,1.1 773 7730 0.4909 1.03 0.953,1.11 758 7579
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.5675 1.01 0.969,1.06 2272 17155 0.5458 1.01 0.97,1.06 2223 16815
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.1365 1.06 0.982,1.14 707 7038 0.07244 1.07 0.993,1.16 688 6908
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.04898 1.07 1.0,1.15 851 8381 0.02754 1.08 1.01,1.16 837 8230
586 Other disorders of the kidney and ureters genitourinary Both 0.26 1.02 0.988,1.04 6202 28774 0.8017 1.01 0.955,1.06 1516 14406
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.4416 1.05 0.928,1.19 284 2825 0.7345 1.03 0.848,1.26 110 1097
586.11 Small kidney genitourinary Both 0.4064 1.07 0.915,1.24 165 1642 0.4295 1.06 0.912,1.24 161 1601
586.12 Vesicoureteral reflux genitourinary Both 0.7816 1.03 0.845,1.25 112 1120 0.7345 1.03 0.848,1.26 110 1097
586.2 Cyst of kidney, acquired genitourinary Both 0.08318 1.05 0.993,1.12 1170 11069 0.1291 1.05 0.986,1.11 1142 10869
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.9705 1.0 0.852,1.18 148 1470 0.7852 1.02 0.869,1.2 146 1444
586.4 Stricture/obstruction of ureter genitourinary Both 0.9397 1.0 0.951,1.06 1536 14675 0.8017 1.01 0.955,1.06 1516 14406
587 Kidney replaced by transpant genitourinary Both 0.7015 1.02 0.936,1.1 612 6120 0.7047 1.02 0.935,1.11 597 6004
588 Disorders resulting from impaired renal function genitourinary Both 0.2891 1.04 0.965,1.13 701 7004 0.5117 1.03 0.941,1.13 511 5156
588.1 Renal osteodystrophy genitourinary Both 0.2228 1.09 0.951,1.24 227 2267 0.1416 1.11 0.967,1.26 222 2225
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.5333 1.03 0.94,1.13 525 5241 0.5117 1.03 0.941,1.13 511 5156
589 Abnormal results of function study of kidney genitourinary Both 0.0955 1.06 0.989,1.14 840 8370 0.08913 1.06 0.991,1.14 822 8207
590 Pyelonephritis genitourinary Both 0.228 1.04 0.977,1.1 1161 11597 0.182 1.04 0.981,1.11 1140 11321
591 Urinary tract infection genitourinary Both 0.4074 1.01 0.985,1.04 8020 27291 0.3281 1.01 0.987,1.04 7868 26675
592 Cystitis and urethritis genitourinary Both 0.07413 1.04 0.996,1.09 2264 19423 0.7534 0.973 0.818,1.16 141 1395
592.1 Cystitis genitourinary Both 0.0537 1.04 0.999,1.09 2149 18531 0.4624 1.04 0.933,1.16 348 3434
592.11 Acute cystitis genitourinary Both 0.4932 1.02 0.963,1.08 1256 12111 0.3811 1.03 0.968,1.09 1238 11812
592.12 Chronic cystitis genitourinary Both 0.7762 0.979 0.845,1.13 199 1972 0.8531 0.986 0.85,1.14 194 1923
592.13 Chronic interstitial cystitis genitourinary Both 0.2723 1.06 0.953,1.19 354 3540 0.4624 1.04 0.933,1.16 348 3434
592.2 Urethritis and urethral syndrome genitourinary Both 0.7816 0.976 0.822,1.16 143 1430 0.7534 0.973 0.818,1.16 141 1395
593 Hematuria genitourinary Both 0.3963 1.01 0.981,1.05 3848 26566 0.8222 0.991 0.917,1.07 714 7044
593.1 Gross hematuria genitourinary Both 0.03981 1.06 1.0,1.13 1201 11351 0.04169 1.06 1.0,1.13 1182 11127
593.2 Microscopic hematuria genitourinary Both 0.7447 0.987 0.914,1.07 724 7225 0.8222 0.991 0.917,1.07 714 7044
594 Urinary calculus genitourinary Both 0.06457 1.03 0.998,1.06 5516 31876 0.3556 1.06 0.938,1.19 280 2787
594.1 Calculus of kidney genitourinary Both 0.0912 1.03 0.996,1.06 5155 31730 0.05495 1.03 0.999,1.06 5049 31056
594.2 Calculus of lower urinary tract genitourinary Both 0.5272 1.04 0.926,1.16 310 3068 0.4786 1.04 0.929,1.17 306 3003
594.3 Calculus of ureter genitourinary Both 0.2904 1.03 0.972,1.1 1104 11000 0.2667 1.04 0.974,1.1 1090 10776
594.8 Renal colic genitourinary Both 0.4093 1.05 0.933,1.18 286 2851 0.3556 1.06 0.938,1.19 280 2787
595 Hydronephrosis genitourinary Both 0.4198 1.02 0.969,1.08 1410 14092 0.3908 1.02 0.97,1.08 1389 13808
596 Other disorders of bladder genitourinary Both 0.8472 1.0 0.964,1.05 2527 23338 0.6776 1.01 0.957,1.07 1341 13287
596.1 Bladder neck obstruction genitourinary Both 0.05888 0.893 0.794,1.0 333 3288 0.05495 0.891 0.792,1.0 330 3239
596.5 Functional disorders of bladder genitourinary Both 0.5861 1.02 0.96,1.07 1368 13608 0.6776 1.01 0.957,1.07 1341 13287
597 Other disorders of urethra and urinary tract genitourinary Both 0.1563 1.05 0.983,1.12 1041 10322 0.4266 0.934 0.789,1.11 157 1538
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.1849 1.06 0.974,1.15 608 6024 0.2239 1.05 0.969,1.14 604 5923
597.2 Urinary complications NEC genitourinary Both 0.7396 1.01 0.944,1.08 861 8600 0.5929 1.02 0.95,1.09 848 8424
597.8 Urethral hypermobility/ISD genitourinary Both 0.4159 0.933 0.789,1.1 158 1578 0.4266 0.934 0.789,1.11 157 1538
598 Abnormal findings on examination of urine genitourinary Both 0.9462 0.998 0.942,1.06 1263 12596 0.8433 1.01 0.948,1.07 1213 12063
598.4 Other cells and casts in urine genitourinary Both 0.7063 1.04 0.848,1.27 91 906 0.863 1.02 0.83,1.25 90 885
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.877 1.0 0.948,1.06 1234 12317 0.8433 1.01 0.948,1.07 1213 12063
599 Other symptoms/disorders or the urinary system genitourinary Both 0.3548 1.01 0.988,1.03 11346 25364 0.5848 0.988 0.946,1.03 2306 19784
599.1 Urinary obstruction genitourinary Both 0.7998 0.989 0.907,1.08 580 5634 0.7925 0.988 0.906,1.08 571 5525
599.2 Retention of urine genitourinary Both 0.3027 0.983 0.95,1.02 4234 24058 0.3715 0.985 0.952,1.02 4166 23491
599.3 Dysuria genitourinary Both 0.8995 1.0 0.967,1.04 3426 23180 0.6209 1.01 0.973,1.05 3377 22620
599.4 Urinary incontinence genitourinary Both 0.8072 0.996 0.964,1.03 4566 22567 0.955 1.0 0.969,1.03 4492 22016
599.5 Frequency of urination and polyuria genitourinary Both 0.3428 1.02 0.983,1.05 4277 23742 0.2606 1.02 0.986,1.05 4200 23166
599.6 Oliguria and anuria genitourinary Both 0.05248 1.09 0.999,1.19 513 5104 0.04169 1.1 1.0,1.2 507 4993
599.7 Urethral discharge genitourinary Both 0.8318 0.976 0.779,1.22 83 830 0.859 0.98 0.781,1.23 82 811
599.8 Other symptoms involving urinary system genitourinary Both 0.1493 1.02 0.991,1.06 4366 23262 0.114 1.03 0.994,1.06 4300 22693
599.9 Other abnormality of urination genitourinary Both 0.6501 0.99 0.948,1.03 2349 20289 0.5848 0.988 0.946,1.03 2306 19784
600 Hyperplasia of prostate genitourinary Male 0.3451 1.02 0.979,1.06 3315 9437 0.2355 1.03 0.984,1.07 3262 9282
601 Inflammatory diseases of prostate genitourinary Male 0.3622 0.967 0.899,1.04 825 7745 0.4864 0.934 0.77,1.13 123 1203
601.1 Prostatitis genitourinary Male 0.7261 1.02 0.917,1.13 378 3680 0.3664 1.11 0.883,1.4 75 753
601.11 Acute prostatitis genitourinary Male 0.1146 0.835 0.668,1.04 95 933 0.105 0.829 0.66,1.04 92 923
601.12 Chronic prostatitis genitourinary Male 0.2443 1.15 0.911,1.44 76 757 0.3664 1.11 0.883,1.4 75 753
601.3 Orchitis and epididymitis genitourinary Male 0.4467 0.956 0.85,1.07 303 3008 0.4656 0.957 0.851,1.08 300 2954
601.4 Balanoposthitis genitourinary Male 0.4345 0.921 0.749,1.13 103 1019 0.3793 0.911 0.74,1.12 102 1003
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.5521 0.943 0.778,1.14 125 1226 0.4864 0.934 0.77,1.13 123 1203
602 Other disorders of prostate genitourinary Male 0.8551 1.01 0.894,1.14 277 2673 0.7621 1.02 0.9,1.15 271 2638
603 Other disorders of testis genitourinary Male 0.1667 1.08 0.968,1.21 348 3468 0.3214 1.1 0.914,1.32 125 1242
603.1 Hydrocele genitourinary Male 0.7345 1.02 0.895,1.17 229 2281 0.6457 1.03 0.902,1.18 228 2242
603.2 Spermatocele genitourinary Male 0.3715 1.09 0.906,1.3 126 1258 0.3214 1.1 0.914,1.32 125 1242
604 Disorders of penis genitourinary Male 0.1866 1.06 0.972,1.16 536 5321 0.05623 1.16 0.996,1.36 170 1677
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.7852 0.976 0.818,1.16 130 1297 0.9506 0.995 0.834,1.19 128 1274
604.3 Peyronie's disease genitourinary Male 0.06026 1.16 0.994,1.35 171 1703 0.05623 1.16 0.996,1.36 170 1677
605 Erectile dysfunction [ED] genitourinary Male 0.1535 1.03 0.989,1.07 2844 10666 0.06166 1.04 0.998,1.09 2813 10490
608 Other disorders of male genital organs genitourinary Male 0.8872 0.996 0.94,1.05 1302 11530 0.9931 1.0 0.944,1.06 1286 11348
609 Male infertility and abnormal spermatozoa genitourinary Male 0.6546 0.975 0.873,1.09 335 3350 0.798 0.976 0.813,1.17 118 1169
609.1 Infertility, male genitourinary Male 0.7396 0.978 0.858,1.11 242 2420 0.6457 0.948 0.754,1.19 78 781
609.11 Azoospermia and oligospermia genitourinary Male 0.6383 0.947 0.754,1.19 79 789 0.6457 0.948 0.754,1.19 78 781
609.2 Abnormal spermatozoa genitourinary Male 0.7362 0.969 0.809,1.16 119 1185 0.798 0.976 0.813,1.17 118 1169
610 Benign mammary dysplasias genitourinary Female 0.2099 1.03 0.986,1.07 3089 13905 0.3221 1.03 0.969,1.1 1011 9872
610.1 Cystic mastopathy genitourinary Female 0.2254 1.04 0.979,1.09 1361 12011 0.2075 1.04 0.98,1.1 1318 11686
610.4 Benign neoplasm of breast genitourinary Female 0.1592 1.03 0.988,1.08 2400 13828 0.1012 1.04 0.993,1.08 2361 13464
610.8 Other specified benign mammary dysplasias genitourinary Female 0.3236 1.03 0.969,1.1 1047 10149 0.3221 1.03 0.969,1.1 1011 9872
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.0871 1.03 0.996,1.06 4952 15509 0.139 1.03 0.99,1.07 2934 15056
611.1 Abnormal mammogram genitourinary Both 0.05623 1.04 0.999,1.07 4074 13538 0.06918 1.06 0.995,1.14 933 8890
611.11 Mammographic microcalcification genitourinary Both 0.05012 1.07 1.0,1.14 962 9131 0.06918 1.06 0.995,1.14 933 8890
611.3 Lump or mass in breast genitourinary Both 0.1517 1.03 0.99,1.07 3011 15449 0.139 1.03 0.99,1.07 2934 15056
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.4764 1.03 0.957,1.1 879 8768 0.4477 0.905 0.7,1.17 68 662
612.1 Galactorrhea genitourinary Both 0.1439 1.15 0.954,1.38 109 1083 0.1169 1.16 0.963,1.41 101 1060
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.4305 1.03 0.955,1.11 672 6710 0.4853 1.03 0.951,1.11 657 6541
612.3 Congenital anomalies of breast genitourinary Both 0.4295 0.903 0.702,1.16 70 676 0.4477 0.905 0.7,1.17 68 662
613 Other nonmalignant breast conditions genitourinary Both 0.07413 1.03 0.997,1.07 3180 18154 0.07586 1.06 0.995,1.12 1170 11616
613.1 Inflammatory disease of breast genitourinary Both 0.1062 1.08 0.984,1.18 504 5035 0.1069 1.08 0.984,1.18 494 4891
613.5 Mastodynia genitourinary Both 0.4742 1.02 0.965,1.08 1313 12942 0.3802 1.03 0.969,1.09 1287 12579
613.7 Other signs and symptoms in breast genitourinary Both 0.5333 1.02 0.949,1.11 722 7109 0.6339 1.02 0.943,1.1 701 6921
613.8 Other specified disorders of breast genitourinary Both 0.3508 1.03 0.963,1.11 800 7961 0.3767 1.03 0.961,1.11 783 7730
613.9 Breast disorder NOS genitourinary Both 0.05129 1.06 1.0,1.12 1211 11947 0.07586 1.06 0.995,1.12 1170 11616
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.7031 0.992 0.954,1.03 2990 16271 0.7278 1.03 0.876,1.21 162 1573
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.863 0.989 0.873,1.12 267 2670 0.9572 0.997 0.879,1.13 260 2595
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.7656 0.985 0.89,1.09 404 4024 0.5224 0.953 0.823,1.1 195 1918
614.31 Acute inflammatory pelvic disease genitourinary Female 0.6223 1.06 0.839,1.34 74 720 0.673 1.05 0.83,1.34 73 690
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.7962 1.02 0.877,1.19 167 1666 0.863 1.01 0.87,1.18 163 1614
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.3972 0.939 0.811,1.09 198 1979 0.5224 0.953 0.823,1.1 195 1918
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.4256 1.07 0.904,1.27 129 1290 0.2477 1.11 0.931,1.32 123 1246
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.5012 0.986 0.945,1.03 2546 16112 0.7278 1.03 0.876,1.21 162 1573
614.51 Cervicitis and endocervicitis genitourinary Female 0.2023 0.909 0.785,1.05 197 1970 0.2128 0.91 0.785,1.06 194 1900
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.9484 0.999 0.955,1.04 2201 15690 0.8433 1.0 0.96,1.05 2157 15249
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.2692 0.893 0.731,1.09 104 1040 0.3155 0.903 0.739,1.1 103 1017
614.54 Abscess or ulceration of vulva genitourinary Female 0.7362 1.03 0.876,1.21 164 1619 0.7278 1.03 0.876,1.21 162 1573
615 Endometriosis genitourinary Female 0.6324 0.986 0.931,1.04 1298 12230 0.6067 0.985 0.929,1.04 1268 11855
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.2286 1.03 0.979,1.09 1415 13522 0.1426 1.04 0.986,1.1 1389 13133
618 Genital prolapse genitourinary Female 0.6209 0.987 0.939,1.04 1707 14626 0.2037 0.93 0.832,1.04 366 3647
618.1 Prolapse of vaginal walls genitourinary Female 0.4645 0.978 0.92,1.04 1179 11187 0.4009 0.974 0.916,1.04 1157 10884
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.8356 1.01 0.917,1.11 444 4418 0.955 0.997 0.904,1.1 434 4315
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.955 0.996 0.883,1.13 286 2855 0.9311 0.995 0.88,1.12 284 2773
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.138 0.92 0.823,1.03 375 3750 0.2037 0.93 0.832,1.04 366 3647
619 Noninflammatory female genital disorders genitourinary Female 0.3758 0.985 0.953,1.02 4598 15534 0.3184 1.03 0.967,1.11 891 8815
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.4009 0.975 0.92,1.03 1262 11294 0.5093 0.98 0.924,1.04 1240 10951
619.2 Disorders of uterus, NEC genitourinary Female 0.1923 1.07 0.969,1.17 444 4435 0.4355 1.04 0.942,1.15 427 4305
619.3 Noninflammatory disorders of cervix genitourinary Female 0.863 1.01 0.911,1.12 391 3892 0.6622 1.02 0.924,1.13 388 3773
619.4 Noninflammatory disorders of vagina genitourinary Female 0.6653 0.989 0.943,1.04 1903 15019 0.861 0.996 0.949,1.05 1859 14597
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.3606 1.03 0.965,1.1 914 9082 0.3184 1.03 0.967,1.11 891 8815
620 Dysplasia of female genital organs genitourinary Female 0.3917 0.95 0.846,1.07 325 3234 0.871 1.01 0.855,1.2 136 1364
620.1 Dysplasia of cervix genitourinary Female 0.9772 0.998 0.843,1.18 142 1420 0.871 1.01 0.855,1.2 136 1364
621 Endometrial hyperplasia genitourinary Female 0.6998 0.978 0.872,1.1 334 3335 0.9183 0.994 0.886,1.11 325 3253
622 Polyp of female genital organs genitourinary Female 0.9484 1.0 0.944,1.06 1191 11723 0.1841 0.925 0.825,1.04 335 3389
622.1 Polyp of corpus uteri genitourinary Female 0.9954 1.0 0.936,1.07 949 9362 1.0 1.0 0.935,1.07 928 9113
622.2 Mucous polyp of cervix genitourinary Female 0.4083 0.954 0.854,1.07 348 3480 0.1841 0.925 0.825,1.04 335 3389
623 Hypertrophy of female genital organs genitourinary Female 0.6138 1.02 0.94,1.11 605 6003 0.4074 1.04 0.953,1.13 590 5831
624 Symptoms involving female genital tract genitourinary Female 0.7278 0.989 0.927,1.05 1013 9695 0.4656 1.02 0.967,1.08 1518 12535
624.1 Dystrophy of female genital tract genitourinary Female 0.9333 0.993 0.849,1.16 168 1680 0.8995 0.99 0.845,1.16 165 1626
624.9 stress incontinence, female genitourinary Female 0.4385 1.02 0.969,1.08 1549 12918 0.4656 1.02 0.967,1.08 1518 12535
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.6368 0.992 0.959,1.03 4618 14394 0.004677 0.907 0.848,0.971 988 9768
625.1 Dyspareunia genitourinary Female 0.008913 0.915 0.856,0.978 1011 10081 0.004677 0.907 0.848,0.971 988 9768
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.2018 0.978 0.945,1.01 4726 13065 0.537 0.974 0.896,1.06 617 5043
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.542 0.988 0.95,1.03 3426 12112 0.8511 0.989 0.878,1.11 295 2895
626.11 Absent or infrequent menstruation genitourinary Female 0.6966 0.986 0.916,1.06 802 6948 0.7079 0.986 0.916,1.06 779 6733
626.12 Excessive or frequent menstruation genitourinary Female 0.3258 0.974 0.925,1.03 1703 9843 0.2897 0.972 0.922,1.02 1660 9549
626.13 Irregular menstrual cycle genitourinary Female 0.865 0.995 0.944,1.05 1543 10197 0.8279 1.01 0.953,1.06 1517 9896
626.14 Irregular menstrual bleeding genitourinary Female 0.9772 0.999 0.928,1.08 777 7408 0.9795 1.0 0.928,1.08 752 7187
626.15 Infertility, female, associated with anovulation genitourinary Female 0.6039 0.969 0.861,1.09 300 3000 0.8511 0.989 0.878,1.11 295 2895
626.2 Dysmenorrhea genitourinary Female 0.9268 0.997 0.937,1.06 1116 8297 0.8995 1.0 0.943,1.07 1094 8045
626.4 Premenstrual tension syndromes genitourinary Female 0.2075 0.923 0.815,1.05 275 2741 0.3148 0.938 0.827,1.06 269 2658
626.8 Infertility, female genitourinary Female 0.4487 0.969 0.892,1.05 630 5218 0.537 0.974 0.896,1.06 617 5043
627 Menopausal and postmenopausal disorders genitourinary Female 0.2042 1.02 0.987,1.06 3657 12296 0.8356 0.986 0.864,1.12 229 2264
627.1 Postmenopausal bleeding genitourinary Female 0.8974 0.996 0.931,1.06 957 8768 0.9727 0.999 0.933,1.07 930 8541
627.2 Symptomatic menopause genitourinary Female 0.09772 1.04 0.993,1.08 2443 11667 0.399 1.05 0.934,1.19 291 2871
627.21 Symptomatic artificial menopause genitourinary Female 0.2985 1.1 0.922,1.3 125 1241 0.2951 1.1 0.922,1.31 122 1209
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.4842 1.04 0.926,1.18 295 2948 0.399 1.05 0.934,1.19 291 2871
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.4315 1.03 0.956,1.11 729 7262 0.4207 1.03 0.956,1.11 710 7077
627.4 Premenopausal menorrhagia genitourinary Female 0.955 1.0 0.894,1.13 305 3020 0.9247 0.994 0.884,1.12 294 2931
627.5 Premature menopause and other ovarian failure genitourinary Female 0.7586 0.98 0.86,1.12 234 2340 0.8356 0.986 0.864,1.12 229 2264
628 Ovarian cyst genitourinary Female 0.2265 0.968 0.919,1.02 1619 11554 0.2661 0.97 0.92,1.02 1579 11228
634 Miscarriage; stillbirth pregnancy complications Female 0.5662 1.02 0.945,1.11 648 6413 0.0263 1.25 1.03,1.53 90 926
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.9036 1.01 0.875,1.16 209 2090 0.6531 1.03 0.895,1.19 205 2029
634.3 Ectopic pregnancy pregnancy complications Female 0.02951 1.24 1.02,1.5 95 950 0.0263 1.25 1.03,1.53 90 926
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.04786 0.9 0.812,0.999 414 4070 0.01349 0.826 0.71,0.961 197 1994
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.4667 0.955 0.842,1.08 272 2720 0.4634 0.953 0.839,1.08 263 2638
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.008913 0.821 0.708,0.952 206 2060 0.01349 0.826 0.71,0.961 197 1994
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.5943 1.02 0.95,1.09 855 6402 0.9931 0.999 0.779,1.28 60 583
636.1 Threatened premature labor pregnancy complications Female 0.6194 1.03 0.916,1.16 298 2980 0.5297 1.04 0.922,1.17 291 2884
636.2 Early onset of delivery pregnancy complications Female 0.8375 0.986 0.862,1.13 233 2330 0.6412 0.968 0.843,1.11 227 2249
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.07762 1.1 0.99,1.22 356 3556 0.03631 1.12 1.01,1.25 348 3448
636.8 Cervical incompetence pregnancy complications Female 0.9863 0.998 0.777,1.28 60 600 0.9931 0.999 0.779,1.28 60 583
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.3784 0.901 0.714,1.14 89 884 0.3581 0.895 0.708,1.13 86 857
638 Other high-risk pregnancy pregnancy complications Female 0.9141 0.996 0.926,1.07 818 5867 0.9886 1.0 0.929,1.08 792 5686
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.9594 0.997 0.903,1.1 421 4210 0.6839 1.03 0.893,1.19 207 2090
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.912 1.01 0.876,1.16 215 2150 0.6839 1.03 0.893,1.19 207 2090
643 Excessive vomiting in pregnancy pregnancy complications Female 0.9977 1.0 0.857,1.17 181 1810 0.869 1.02 0.815,1.27 84 843
643.1 Hyperemesis gravidarum pregnancy complications Female 0.9204 1.01 0.812,1.26 87 870 0.869 1.02 0.815,1.27 84 843
644 Anemia during pregnancy pregnancy complications Female 0.3155 0.918 0.777,1.08 154 1540 0.3999 0.931 0.787,1.1 153 1492
645 Late pregnancy and failed induction pregnancy complications Female 0.03548 1.13 1.01,1.27 286 2860 0.0263 1.14 1.02,1.28 280 2767
646 Other complications of pregnancy NEC pregnancy complications Female 0.5212 0.973 0.895,1.06 622 5063 0.6442 0.98 0.9,1.07 609 4904
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.7211 1.03 0.872,1.22 152 1520 0.8091 1.02 0.876,1.18 179 1766
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.5728 1.04 0.9,1.21 182 1820 0.8091 1.02 0.876,1.18 179 1766
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.9616 1.0 0.936,1.07 968 6387 0.3155 1.05 0.952,1.16 399 4023
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.3006 1.05 0.954,1.16 413 4130 0.3155 1.05 0.952,1.16 399 4023
650 Normal delivery pregnancy complications Female 0.0537 1.08 0.999,1.16 757 6412 0.0166 1.1 1.02,1.18 738 6201
651 Multiple gestation pregnancy complications Female 0.1986 0.872 0.707,1.07 100 1000 0.2477 0.883 0.714,1.09 98 975
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.01738 1.12 1.02,1.23 461 4586 0.01698 1.12 1.02,1.23 452 4437
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.8356 0.99 0.897,1.09 443 4189 0.9616 0.998 0.903,1.1 430 4052
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.3296 1.05 0.955,1.15 482 4820 0.5649 1.05 0.892,1.23 158 1576
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.1047 1.09 0.983,1.2 402 4020 0.1542 1.08 0.972,1.19 392 3890
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.7228 1.03 0.877,1.21 163 1630 0.5649 1.05 0.892,1.23 158 1576
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.4467 1.02 0.964,1.09 1244 8117 0.2891 1.05 0.956,1.16 446 4220
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.2618 1.06 0.96,1.16 451 4371 0.2891 1.05 0.956,1.16 446 4220
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.857 1.01 0.89,1.15 246 2460 0.7534 1.04 0.802,1.36 59 573
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.7311 1.05 0.806,1.36 59 590 0.7534 1.04 0.802,1.36 59 573
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.8974 0.99 0.854,1.15 195 1950 0.8414 1.02 0.875,1.18 191 1889
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.2084 1.06 0.969,1.16 504 4732 0.1968 1.06 0.969,1.16 487 4572
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.7413 0.983 0.889,1.09 420 4080 0.7379 0.983 0.886,1.09 405 3943
665 Obstetrical/birth trauma pregnancy complications Female 0.8433 1.01 0.934,1.09 751 6161 0.5321 1.02 0.949,1.11 727 5972
669 Complications of labor and delivery NEC pregnancy complications Female 0.787 1.01 0.933,1.1 671 5265 0.861 1.01 0.928,1.09 654 5096
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.8492 1.01 0.871,1.18 172 1720 0.912 1.01 0.862,1.18 164 1666
674 Other complications of the puerperium NEC pregnancy complications Female 0.07943 1.14 0.984,1.32 181 1810 0.05888 1.15 0.995,1.34 178 1756
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.125 1.15 0.963,1.37 122 1220 0.08128 1.17 0.981,1.4 120 1184
681 Superficial cellulitis and abscess dermatologic Both 0.3373 1.01 0.985,1.05 5078 31991 0.4217 1.02 0.966,1.09 1214 12051
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.9183 1.0 0.936,1.08 862 8581 0.871 1.01 0.937,1.08 845 8379
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.03162 1.08 1.01,1.16 781 7775 0.05012 1.08 1.0,1.16 758 7594
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.2805 0.971 0.921,1.02 1533 15238 0.3192 0.973 0.922,1.03 1502 14914
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.6792 0.989 0.94,1.04 1649 16359 0.7962 0.993 0.943,1.05 1621 16008
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.6998 0.989 0.934,1.05 1291 12850 0.8147 0.993 0.937,1.05 1267 12576
681.7 Cellulitis and abscess of trunk dermatologic Both 0.4266 1.02 0.966,1.08 1238 12342 0.4217 1.02 0.966,1.09 1214 12051
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.6109 1.01 0.963,1.07 1660 16466 0.859 0.983 0.814,1.19 120 1184
686.1 Carbuncle and furuncle dermatologic Both 0.2265 1.07 0.961,1.18 390 3881 0.1986 1.07 0.965,1.19 380 3770
686.2 Impetigo dermatologic Both 0.5636 1.04 0.92,1.17 310 3068 0.6457 1.03 0.912,1.16 304 3006
686.3 Pilonidal cyst dermatologic Both 0.875 0.985 0.818,1.19 120 1200 0.9594 0.995 0.827,1.2 118 1170
686.4 Pyogenic granuloma dermatologic Both 0.8128 0.977 0.81,1.18 121 1205 0.859 0.983 0.814,1.19 120 1184
687 Symptoms affecting skin dermatologic Both 0.2148 1.02 0.99,1.05 6119 25901 0.2931 1.02 0.986,1.05 4837 25096
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.7568 1.0 0.975,1.03 5371 25824 0.6501 1.01 0.977,1.04 5253 25332
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.3034 1.02 0.986,1.05 5264 25870 0.6368 1.01 0.977,1.04 5068 25379
687.3 Changes in skin texture dermatologic Both 0.8831 0.991 0.878,1.12 294 2926 0.9772 0.998 0.883,1.13 287 2857
687.4 Disturbance of skin sensation dermatologic Both 0.2594 1.02 0.987,1.05 4942 25586 0.2931 1.02 0.986,1.05 4837 25096
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.0257 1.03 1.0,1.06 7192 31086 0.02344 1.03 1.0,1.06 7030 30451
690 Erythematosquamous dermatosis dermatologic Both 0.3828 1.02 0.981,1.05 3810 26256 0.3811 1.02 0.981,1.05 3717 25648
690.1 Seborrheic dermatitis dermatologic Both 0.3981 1.01 0.981,1.05 3802 26218 0.3811 1.02 0.981,1.05 3717 25648
691 Congenital anomalies of skin dermatologic Both 0.309 1.05 0.954,1.16 411 4110 0.3289 1.05 0.951,1.16 400 4018
694 Dyschromia and Vitiligo dermatologic Both 0.2917 1.03 0.974,1.09 1286 12819 0.8892 0.982 0.762,1.27 68 672
694.1 Vitiligo dermatologic Both 0.6761 0.956 0.772,1.18 94 931 0.6823 0.956 0.77,1.19 89 908
694.2 Other dyschromia dermatologic Both 0.2404 1.04 0.976,1.1 1146 11421 0.2432 1.04 0.976,1.1 1122 11134
694.3 Vascular disorders of skin dermatologic Both 0.8414 0.975 0.757,1.25 69 686 0.8892 0.982 0.762,1.27 68 672
695 Erythematous conditions dermatologic Both 0.4887 1.01 0.976,1.05 3180 24642 0.984 1.0 0.913,1.1 498 4988
695.2 Bullous dermatoses dermatologic Both 0.1186 1.21 0.953,1.53 68 658 0.1186 1.21 0.953,1.53 67 643
695.3 Rosacea dermatologic Both 0.1021 1.05 0.991,1.1 1405 14019 0.1021 1.05 0.991,1.11 1380 13683
695.4 Lupus (localized and systemic) dermatologic Both 0.743 1.01 0.931,1.11 556 5556 0.875 1.01 0.921,1.1 518 5150
695.41 Cutaneous lupus erythematosus dermatologic Both 0.2812 1.08 0.938,1.25 196 1955 0.3258 1.07 0.931,1.24 191 1897
695.42 Systemic lupus erythematosus dermatologic Both 0.8892 1.01 0.921,1.1 530 5287 0.875 1.01 0.921,1.1 518 5150
695.7 Prurigo and Lichen dermatologic Both 0.9727 0.998 0.904,1.1 429 4275 0.867 0.991 0.897,1.1 417 4167
695.8 Other specified erythematous conditions dermatologic Both 0.4842 1.03 0.948,1.12 613 6111 0.4436 1.03 0.951,1.12 605 5956
695.9 Unspecified erythematous condition dermatologic Both 0.867 1.01 0.92,1.1 513 5102 0.984 1.0 0.913,1.1 498 4988
696 Psoriasis and related disorders dermatologic Both 0.4375 1.02 0.964,1.09 1080 10781 0.01862 1.17 1.03,1.33 221 2202
696.3 Pityriasis dermatologic Both 0.9247 1.01 0.797,1.28 64 640 0.863 0.979 0.768,1.25 62 625
696.4 Psoriasis dermatologic Both 0.4842 1.02 0.96,1.09 1014 10115 0.01862 1.17 1.03,1.33 221 2202
696.41 Psoriasis vulgaris dermatologic Both 0.6152 1.02 0.951,1.09 918 9161 0.6714 1.01 0.948,1.09 899 8966
696.42 Psoriatic arthropathy dermatologic Both 0.01862 1.17 1.03,1.33 225 2250 0.01862 1.17 1.03,1.33 221 2202
697 Sarcoidosis dermatologic Both 0.6887 0.975 0.861,1.1 265 2650 0.7047 0.976 0.86,1.11 257 2587
698 Pruritus and related conditions dermatologic Both 0.8166 1.01 0.957,1.06 1686 16680 0.6745 1.01 0.961,1.06 1643 16277
700 Corns and callosities dermatologic Both 0.1986 1.05 0.975,1.13 764 7615 0.2198 1.05 0.972,1.13 747 7451
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.4169 0.988 0.961,1.02 5838 31889 0.8511 0.989 0.881,1.11 324 3192
701.1 Keratoderma, acquired dermatologic Both 0.5834 0.971 0.874,1.08 389 3845 0.8166 0.988 0.888,1.1 377 3766
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.2421 1.03 0.98,1.08 1705 16953 0.4285 1.02 0.971,1.07 1658 16573
701.3 Circumscribed scleroderma dermatologic Both 0.7925 1.01 0.918,1.12 434 4334 0.631 1.02 0.928,1.13 424 4225
701.4 Keloid scar dermatologic Both 0.9333 1.0 0.913,1.1 454 4503 0.8279 1.01 0.918,1.11 445 4394
701.5 Abnormal granulation tissue dermatologic Both 0.873 0.991 0.883,1.11 328 3260 0.8511 0.989 0.881,1.11 324 3192
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.1387 1.02 0.993,1.05 5351 24908 0.9908 1.0 0.768,1.31 61 609
702.1 Actinic keratosis dermatologic Both 0.2767 1.02 0.984,1.06 3236 22206 0.2173 1.02 0.986,1.06 3177 21747
702.2 Seborrheic keratosis dermatologic Both 0.1791 1.02 0.99,1.06 4151 26248 0.1472 1.02 0.991,1.06 4060 25682
702.4 Degenerative skin disorders dermatologic Both 0.7656 1.04 0.802,1.35 63 624 0.9908 1.0 0.768,1.31 61 609
703 Diseases of nail, NOS dermatologic Both 0.414 0.973 0.913,1.04 1033 10222 0.3882 1.04 0.953,1.13 566 5663
703.1 Ingrowing nail dermatologic Both 0.3076 1.04 0.961,1.14 580 5773 0.3882 1.04 0.953,1.13 566 5663
704 Diseases of hair and hair follicles dermatologic Both 0.1208 1.03 0.991,1.08 2321 22718 0.1807 1.04 0.982,1.1 1250 12537
704.1 Alopecia dermatologic Both 0.4467 1.02 0.963,1.09 1074 10601 0.1057 0.785 0.586,1.05 56 562
704.11 Alopecia Areata dermatologic Both 0.1175 0.795 0.596,1.06 58 580 0.1057 0.785 0.586,1.05 56 562
704.2 Hirsutism dermatologic Both 0.9376 0.995 0.868,1.14 227 2263 0.5534 0.958 0.833,1.1 212 2203
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.1528 1.04 0.985,1.1 1286 12791 0.1807 1.04 0.982,1.1 1250 12537
705 Disorders of sweat glands dermatologic Both 0.3266 1.05 0.954,1.15 439 4376 0.778 1.01 0.941,1.08 817 8237
705.1 Dyshidrosis dermatologic Both 0.03162 1.21 1.02,1.45 114 1131 0.04786 1.2 1.0,1.43 111 1104
705.3 Hidradenitis dermatologic Both 0.8974 0.99 0.851,1.15 183 1815 0.9863 1.0 0.861,1.17 180 1775
705.8 Hyperhidrosis dermatologic Both 0.9247 1.0 0.936,1.08 846 8429 0.778 1.01 0.941,1.08 817 8237
706 Diseases of sebaceous glands dermatologic Both 0.7379 0.995 0.964,1.03 4454 32859 0.02239 0.928 0.871,0.989 1088 10909
706.1 Acne dermatologic Both 0.02512 1.05 1.01,1.1 1931 17499 0.01585 1.06 1.01,1.11 1888 17082
706.2 Sebaceous cyst dermatologic Both 0.6902 0.991 0.948,1.04 2150 21106 0.6653 0.99 0.947,1.04 2097 20644
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.02754 0.932 0.875,0.992 1124 11122 0.02239 0.928 0.871,0.989 1088 10909
707 Chronic ulcer of skin dermatologic Both 0.2917 1.02 0.98,1.07 2193 21811 0.2642 1.03 0.976,1.09 1314 13068
707.1 Decubitus ulcer dermatologic Both 0.5546 1.03 0.943,1.12 600 5984 0.4036 1.04 0.953,1.13 594 5859
707.2 Chronic ulcer of leg or foot dermatologic Both 0.5702 0.978 0.905,1.06 721 7166 0.7096 0.985 0.912,1.06 716 7022
707.3 Chronic ulcer of unspecified site dermatologic Both 0.2931 1.03 0.975,1.09 1339 13370 0.2642 1.03 0.976,1.09 1314 13068
709 Diffuse diseases of connective tissue dermatologic Both 0.9931 1.0 0.94,1.06 1086 10825 0.5035 0.973 0.897,1.05 640 6390
709.2 Sicca syndrome dermatologic Both 0.3311 1.05 0.949,1.17 365 3650 0.3404 1.05 0.948,1.17 349 3566
709.3 Systemic sclerosis dermatologic Both 0.03981 1.16 1.01,1.35 184 1840 0.01778 1.19 1.03,1.38 180 1798
709.5 Dermatomyositis dermatologic Both 0.171 0.841 0.656,1.08 70 700 0.2307 0.859 0.671,1.1 69 693
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.5888 0.938 0.743,1.18 78 780 0.6457 0.947 0.751,1.19 78 765
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.3236 0.96 0.887,1.04 659 6563 0.5035 0.973 0.897,1.05 640 6390
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.01514 1.04 1.01,1.07 5120 27320 0.01549 1.35 1.06,1.71 60 616
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.01 1.36 1.08,1.72 64 626 0.01549 1.35 1.06,1.71 60 616
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.01622 0.92 0.859,0.985 954 9524 0.02188 0.919 0.855,0.988 858 8489
710.1 Osteomyelitis musculoskeletal Both 0.007079 0.908 0.847,0.974 914 9127 0.02188 0.919 0.855,0.988 858 8489
710.11 Acute osteomyelitis musculoskeletal Both 0.0123 0.873 0.784,0.971 425 4234 0.01622 0.877 0.788,0.976 418 4150
710.12 Chronic osteomyelitis musculoskeletal Both 0.3936 0.954 0.856,1.06 378 3758 0.3639 0.951 0.852,1.06 374 3688
710.19 Unspecified osteomyelitis musculoskeletal Both 0.02089 0.919 0.855,0.987 867 8656 0.02188 0.919 0.855,0.988 858 8489
711 Arthropathy associated with infections musculoskeletal Both 0.1045 0.908 0.808,1.02 314 3124 0.1432 0.9 0.782,1.04 217 2169
711.1 Pyogenic arthritis musculoskeletal Both 0.2099 0.916 0.798,1.05 223 2206 0.1432 0.9 0.782,1.04 217 2169
712 Infective connective tissue disorders musculoskeletal Both 0.8279 0.982 0.829,1.16 136 1360 0.811 0.979 0.826,1.16 134 1330
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.9226 1.01 0.875,1.16 222 2214 0.875 1.02 0.837,1.23 117 1155
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.8166 1.02 0.844,1.24 118 1180 0.875 1.02 0.837,1.23 117 1155
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.1493 1.04 0.987,1.09 1649 14662 0.1581 1.04 0.984,1.1 1314 12038
714.1 Rheumatoid arthritis musculoskeletal Both 0.1538 1.04 0.985,1.1 1342 12332 0.1581 1.04 0.984,1.1 1314 12038
715 Other inflammatory spondylopathies musculoskeletal Both 0.547 1.02 0.956,1.09 979 9761 0.8492 1.01 0.872,1.18 172 1722
715.1 Sacroiliitis NEC musculoskeletal Both 0.2455 0.917 0.793,1.06 212 2120 0.2965 0.925 0.798,1.07 206 2083
715.2 Ankylosing spondylitis musculoskeletal Both 0.8913 0.99 0.851,1.15 177 1760 0.8492 1.01 0.872,1.18 172 1722
716 Other arthropathies musculoskeletal Both 0.175 1.02 0.993,1.04 10893 26011 0.1089 1.02 0.996,1.04 10617 25439
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.6808 1.03 0.883,1.21 155 1540 0.8128 1.02 0.87,1.19 152 1507
716.2 Unspecified monoarthritis musculoskeletal Both 0.2193 1.12 0.933,1.35 116 1156 0.2851 1.11 0.918,1.34 112 1135
716.9 Arthropathy NOS musculoskeletal Both 0.166 1.02 0.993,1.04 10831 26002 0.1089 1.02 0.996,1.04 10617 25439
717 Polymyalgia Rheumatica musculoskeletal Both 0.6324 0.965 0.834,1.12 210 2061 0.7413 0.976 0.843,1.13 205 2028
720 Spinal stenosis musculoskeletal Both 0.6457 0.991 0.956,1.03 3298 24117 0.7745 0.994 0.952,1.04 2375 20061
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.7396 0.993 0.952,1.04 2415 20454 0.7745 0.994 0.952,1.04 2375 20061
721 Spondylosis and allied disorders musculoskeletal Both 0.4864 1.01 0.98,1.04 4494 27007 0.5929 1.04 0.903,1.19 210 2045
721.1 Spondylosis without myelopathy musculoskeletal Both 0.4446 1.01 0.98,1.05 4206 26584 0.4121 1.01 0.981,1.05 4121 26023
721.2 Spondylosis with myelopathy musculoskeletal Both 0.0955 0.937 0.869,1.01 740 7398 0.1 0.938 0.869,1.01 729 7252
721.8 Other allied disorders of spine musculoskeletal Both 0.7345 1.02 0.891,1.18 212 2099 0.5929 1.04 0.903,1.19 210 2045
722 Intervertebral disc disorders musculoskeletal Both 0.16 0.979 0.95,1.01 5242 28702 0.04074 0.946 0.897,0.998 1549 15345
722.1 Displacement of intervertebral disc musculoskeletal Both 0.1531 0.973 0.937,1.01 3038 26827 0.195 0.975 0.938,1.01 2982 26262
722.3 Schmorl's nodes musculoskeletal Both 0.6081 0.951 0.786,1.15 115 1140 0.5702 0.946 0.779,1.15 113 1117
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.8913 0.998 0.962,1.03 3338 26140 0.9376 0.999 0.963,1.04 3266 25598
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.5458 0.971 0.883,1.07 464 4634 0.5346 0.97 0.881,1.07 456 4522
722.8 Postlaminectomy syndrome musculoskeletal Both 0.7295 0.981 0.878,1.1 336 3360 0.4688 0.959 0.857,1.07 331 3299
722.9 Other and unspecified disc disorder musculoskeletal Both 0.0257 0.942 0.893,0.993 1569 15676 0.04074 0.946 0.897,0.998 1549 15345
723 Other disorders of cervical region musculoskeletal Both 0.2992 0.961 0.891,1.04 761 7610 0.3776 0.93 0.792,1.09 177 1835
723.1 Torticollis musculoskeletal Both 0.3475 0.928 0.793,1.09 187 1870 0.3776 0.93 0.792,1.09 177 1835
724 Other and unspecified disorders of back musculoskeletal Both 0.04365 0.963 0.929,0.999 3338 26730 0.001698 0.907 0.854,0.964 1220 12151
724.1 Disorders of sacrum musculoskeletal Both 0.9638 0.999 0.952,1.05 1804 17663 0.9795 0.999 0.952,1.05 1784 17239
724.2 Disorders of coccyx musculoskeletal Both 0.3436 1.05 0.945,1.17 331 3290 0.3467 1.05 0.945,1.18 323 3220
724.8 Other symptoms referable to back musculoskeletal Both 0.7482 0.988 0.917,1.06 753 7499 0.7745 0.989 0.917,1.07 740 7331
724.9 Other unspecified back disorders musculoskeletal Both 0.002291 0.911 0.858,0.967 1246 12418 0.001698 0.907 0.854,0.964 1220 12151
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.5754 1.01 0.982,1.03 7682 25455 0.6792 0.985 0.919,1.06 870 8652
726.1 Enthesopathy musculoskeletal Both 0.2056 1.02 0.99,1.05 5795 25454 0.1528 1.02 0.992,1.05 5702 24875
726.2 Synoviopathy musculoskeletal Both 0.5035 1.03 0.953,1.1 774 7723 0.3681 1.03 0.961,1.11 766 7552
726.3 Bursitis musculoskeletal Both 0.2911 0.97 0.916,1.03 1339 13090 0.2415 0.966 0.912,1.02 1312 12784
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.7534 0.989 0.923,1.06 889 8846 0.6792 0.985 0.919,1.06 870 8652
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.537 0.991 0.963,1.02 5811 25457 0.7464 1.03 0.859,1.24 114 1095
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.414 1.02 0.976,1.06 2342 20541 0.2698 1.02 0.982,1.07 2310 20060
727.2 Bursitis disorders musculoskeletal Both 0.2938 0.941 0.84,1.05 341 3381 0.2911 0.94 0.839,1.05 335 3298
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.02512 0.931 0.874,0.991 1109 11034 0.03162 0.933 0.875,0.994 1085 10731
727.5 Rupture of synovium musculoskeletal Both 0.2 1.07 0.965,1.19 376 3718 0.1667 1.08 0.97,1.19 367 3636
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.6714 0.99 0.945,1.04 1927 18092 0.7211 0.991 0.946,1.04 1895 17681
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.9204 0.995 0.91,1.09 520 5187 0.8872 0.993 0.907,1.09 507 5045
727.8 Plica syndrome musculoskeletal Both 0.7145 1.03 0.863,1.24 115 1117 0.7464 1.03 0.859,1.24 114 1095
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.7311 1.01 0.971,1.04 3433 24951 0.8831 1.01 0.898,1.13 306 3035
728.1 Muscular calcification and ossification musculoskeletal Both 0.9036 1.02 0.797,1.29 69 682 0.9183 1.01 0.796,1.29 69 669
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.7907 1.02 0.89,1.17 230 2298 0.7691 1.02 0.891,1.17 228 2240
728.7 Fasciitis musculoskeletal Both 0.09772 1.04 0.993,1.09 2056 19042 0.8831 1.01 0.898,1.13 306 3035
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.695 1.02 0.912,1.15 310 3095 0.8831 1.01 0.898,1.13 306 3035
729 Other disorders of soft tissues musculoskeletal Both 0.7311 1.01 0.967,1.05 2618 22751 0.2028 0.833 0.629,1.1 52 512
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.3614 1.13 0.871,1.46 63 630 0.3119 1.14 0.882,1.48 63 606
729.3 Panniculitis musculoskeletal Both 0.3119 0.899 0.73,1.11 100 1000 0.3281 0.9 0.73,1.11 98 976
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.1786 0.825 0.623,1.09 53 530 0.2028 0.833 0.629,1.1 52 512
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.05012 0.837 0.7,1.0 145 1441 0.06457 0.845 0.706,1.01 142 1405
732 Osteochondropathies musculoskeletal Both 0.5649 1.04 0.919,1.17 289 2882 0.3141 1.13 0.894,1.42 70 700
732.1 Juvenile osteochondrosis musculoskeletal Both 0.9226 0.992 0.842,1.17 157 1570 0.9484 0.995 0.844,1.17 155 1535
732.7 Osteochondritis dissecans musculoskeletal Both 0.3467 1.12 0.887,1.41 71 710 0.3141 1.13 0.894,1.42 70 700
733 Other disorders of bone and cartilage musculoskeletal Both 0.01072 1.05 1.01,1.09 3481 21966 0.4592 1.09 0.874,1.35 79 776
733.2 Cyst of bone musculoskeletal Both 0.7907 1.02 0.871,1.2 162 1613 0.7145 1.03 0.878,1.21 162 1577
733.4 Aseptic necrosis of bone musculoskeletal Both 0.9311 0.995 0.899,1.1 405 4042 0.912 0.994 0.897,1.1 397 3950
733.6 Costochondritis musculoskeletal Both 0.4074 1.05 0.932,1.19 275 2742 0.3475 1.06 0.937,1.2 267 2658
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.8035 1.01 0.934,1.09 701 7003 0.6252 1.02 0.943,1.1 693 6848
733.9 Chondromalacia musculoskeletal Both 0.4169 1.09 0.881,1.36 80 800 0.4592 1.09 0.874,1.35 79 776
735 Acquired foot deformities musculoskeletal Both 0.4246 1.02 0.976,1.06 2431 23304 0.3917 0.972 0.911,1.04 1024 10044
735.1 Flat foot musculoskeletal Both 0.526 1.03 0.937,1.14 437 4355 0.4677 1.04 0.941,1.14 431 4268
735.2 Acquired toe deformities musculoskeletal Both 0.2018 1.05 0.976,1.12 869 8616 0.1524 1.09 0.969,1.22 291 2910
735.21 Hammer toe (acquired) musculoskeletal Both 0.5808 1.03 0.938,1.12 509 5041 0.4875 1.03 0.944,1.13 505 4923
735.23 Hallux rigidus musculoskeletal Both 0.1462 1.09 0.971,1.22 299 2975 0.1524 1.09 0.969,1.22 291 2910
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.375 0.971 0.911,1.04 1039 10308 0.3917 0.972 0.911,1.04 1024 10044
736 Other acquired deformities of limbs musculoskeletal Both 0.6982 1.01 0.964,1.06 1997 19771 0.3855 0.944 0.83,1.07 253 2493
736.1 Acquired deformities of forearm musculoskeletal Both 0.8831 1.02 0.826,1.25 90 892 0.8414 1.02 0.83,1.26 89 878
736.2 Acquired deformities of finger musculoskeletal Both 0.2399 1.1 0.94,1.28 169 1684 0.3436 1.08 0.922,1.26 166 1650
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.3631 1.06 0.932,1.21 239 2382 0.3083 1.07 0.939,1.22 238 2331
736.5 Acquired deformities of knee musculoskeletal Both 0.861 1.01 0.873,1.18 184 1834 0.8017 1.02 0.878,1.18 183 1801
736.6 Unequal leg length (acquired) musculoskeletal Both 0.2805 0.932 0.82,1.06 256 2555 0.3855 0.944 0.83,1.07 253 2493
737 Curvature of spine musculoskeletal Both 0.4305 0.977 0.922,1.04 1268 12573 0.3664 0.97 0.908,1.04 976 9544
737.1 Kyphosis (acquired) musculoskeletal Both 0.1936 0.931 0.835,1.04 383 3819 0.2286 0.935 0.839,1.04 378 3750
737.2 Lordosis (acquired) musculoskeletal Both 0.6998 1.05 0.817,1.35 65 650 0.537 1.08 0.843,1.39 64 639
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.2218 0.96 0.899,1.03 987 9782 0.3664 0.97 0.908,1.04 976 9544
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.2999 0.976 0.931,1.02 1968 19555 0.859 1.01 0.938,1.08 849 8426
738.4 Acquired spondylolisthesis musculoskeletal Both 0.8551 1.01 0.939,1.08 863 8617 0.859 1.01 0.938,1.08 849 8426
739 Contracture of joint musculoskeletal Both 0.07762 0.922 0.842,1.01 522 5203 0.05248 0.914 0.834,1.0 518 5084
740 Osteoarthrosis musculoskeletal Both 0.02884 1.03 1.0,1.05 13133 25195 0.02455 1.03 1.0,1.05 12392 24546
740.1 Osteoarthritis; localized musculoskeletal Both 0.05012 1.03 1.0,1.06 5329 22764 0.1422 1.07 0.978,1.17 506 5040
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.03631 1.04 1.0,1.07 4543 21500 0.0263 1.04 1.0,1.07 4462 21041
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.1754 1.06 0.973,1.16 514 5125 0.1422 1.07 0.978,1.17 506 5040
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.1589 1.04 0.984,1.11 1266 9917 0.133 1.05 0.986,1.11 1233 9707
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.4977 1.04 0.928,1.17 303 2974 0.4159 1.05 0.935,1.18 297 2916
740.9 Osteoarthrosis NOS musculoskeletal Both 0.0389 1.02 1.0,1.05 12648 25075 0.02455 1.03 1.0,1.05 12392 24546
741 Symptoms and disorders of the joints musculoskeletal Both 0.3467 1.01 0.986,1.04 6764 29838 0.5834 1.07 0.832,1.39 53 514
741.1 Ankylosis of joint musculoskeletal Both 0.879 0.989 0.861,1.14 209 2088 0.879 0.989 0.86,1.14 207 2046
741.2 Stiffness of joint musculoskeletal Both 0.4592 0.976 0.914,1.04 995 9908 0.526 0.979 0.916,1.05 979 9691
741.3 Difficulty in walking musculoskeletal Both 0.861 0.996 0.949,1.04 1854 17778 0.9977 1.0 0.953,1.05 1833 17400
741.4 Joint effusions musculoskeletal Both 0.08318 1.04 0.995,1.09 1930 19185 0.04786 1.05 1.0,1.1 1895 18764
741.5 Hemarthrosis musculoskeletal Both 0.8831 0.981 0.764,1.26 64 640 0.8995 0.984 0.766,1.26 64 621
741.6 Villonodular synovitis musculoskeletal Both 0.5559 1.08 0.835,1.4 53 522 0.5834 1.07 0.832,1.39 53 514
742 Derangement of joint, non-traumatic musculoskeletal Both 0.1514 1.03 0.991,1.06 3462 27650 0.08318 1.03 0.996,1.07 3162 26266
742.1 Loose body in joint musculoskeletal Both 0.3532 0.917 0.763,1.1 131 1295 0.3828 0.922 0.767,1.11 130 1272
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.1459 1.1 0.967,1.25 243 2414 0.1854 1.09 0.958,1.25 239 2365
742.8 Articular cartilage disorder musculoskeletal Both 0.7534 1.02 0.886,1.18 191 1896 0.8204 1.02 0.879,1.18 189 1861
742.9 Other derangement of joint musculoskeletal Both 0.1479 1.03 0.991,1.07 3212 26883 0.08318 1.03 0.996,1.07 3162 26266
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.04074 1.03 1.0,1.05 7571 30458 0.02884 1.03 1.0,1.06 5666 28859
743.1 Osteoporosis musculoskeletal Both 0.2767 1.02 0.982,1.06 2982 15823 0.879 1.01 0.882,1.16 224 2236
743.11 Osteoporosis NOS musculoskeletal Both 0.1845 1.03 0.987,1.07 2931 15630 0.1574 1.03 0.989,1.07 2852 15278
743.12 Senile osteoporosis musculoskeletal Both 0.8337 1.01 0.919,1.11 481 4333 0.7834 1.01 0.922,1.11 472 4227
743.13 Other specified osteoporosis musculoskeletal Both 0.9268 1.01 0.88,1.15 231 2290 0.879 1.01 0.882,1.16 224 2236
743.2 Pathologic fracture musculoskeletal Both 0.01549 1.09 1.02,1.17 872 8504 0.1054 1.17 0.968,1.41 111 1121
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.2489 1.06 0.958,1.18 385 3799 0.1828 1.07 0.967,1.19 379 3728
743.22 Pathologic fracture of femur musculoskeletal Both 0.08913 1.17 0.976,1.41 116 1143 0.1054 1.17 0.968,1.41 111 1121
743.4 Stress fracture musculoskeletal Both 0.2014 1.08 0.96,1.21 291 2882 0.1799 1.08 0.964,1.22 287 2817
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.02818 1.03 1.0,1.06 5795 29464 0.02884 1.03 1.0,1.06 5666 28859
745 Pain in joint musculoskeletal Both 0.227 1.01 0.992,1.03 15755 22596 0.138 1.02 0.995,1.04 15472 22081
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.863 0.996 0.949,1.05 1811 18049 0.04677 0.897 0.806,0.999 390 3925
747.1 Cardiac congenital anomalies congenital anomalies Both 0.5047 1.02 0.965,1.07 1446 14417 0.9661 1.0 0.895,1.12 328 3337
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.8185 1.01 0.923,1.11 519 5181 0.826 1.01 0.921,1.11 503 5077
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.7638 1.01 0.933,1.1 632 6299 0.863 1.01 0.927,1.09 617 6186
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.859 1.01 0.904,1.13 342 3387 0.9661 1.0 0.895,1.12 328 3337
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.1132 0.919 0.827,1.02 402 4014 0.04677 0.897 0.806,0.999 390 3925
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.03388 0.778 0.618,0.981 93 930 0.0631 0.801 0.634,1.01 88 909
749 Congenital anomalies of face and neck congenital anomalies Both 0.3027 1.05 0.956,1.16 455 4540 0.9162 1.01 0.809,1.27 89 873
749.1 Cleft palate congenital anomalies Both 0.8128 0.974 0.781,1.21 81 791 0.7656 0.967 0.775,1.21 80 780
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.9354 0.991 0.794,1.24 90 897 0.9162 1.01 0.809,1.27 89 873
750 Digestive congenital anomalies congenital anomalies Both 0.06457 1.07 0.996,1.16 739 7382 0.6902 1.03 0.89,1.19 178 1743
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.04898 1.12 1.0,1.25 307 3069 0.5458 1.08 0.841,1.39 57 556
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.514 1.07 0.874,1.31 96 944 0.4046 1.09 0.889,1.34 92 928
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.1542 1.18 0.94,1.48 77 767 0.1531 1.18 0.941,1.48 77 756
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.2312 1.12 0.932,1.34 121 1210 0.1841 1.13 0.943,1.36 117 1187
750.15 Congenital anomalies of stomach congenital anomalies Both 0.5768 1.07 0.836,1.38 57 567 0.5458 1.08 0.841,1.39 57 556
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.9954 1.0 0.907,1.1 438 4363 0.6902 1.03 0.89,1.19 178 1743
750.21 Congenital anomalies of intestine congenital anomalies Both 0.9594 1.0 0.884,1.14 262 2613 0.9226 1.01 0.886,1.14 258 2552
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.8147 1.02 0.88,1.18 180 1790 0.6902 1.03 0.89,1.19 178 1743
751 Genitourinary congenital anomalies congenital anomalies Both 0.9057 1.0 0.955,1.05 1682 16764 0.7161 1.03 0.877,1.21 155 1526
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.7925 1.01 0.924,1.11 491 4897 0.6531 1.04 0.873,1.24 129 1283
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.9484 1.0 0.897,1.12 328 3280 0.9908 1.0 0.893,1.12 320 3182
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.4385 1.07 0.901,1.27 132 1301 0.6531 1.04 0.873,1.24 129 1283
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.826 1.01 0.947,1.07 1139 11355 0.05495 1.13 0.998,1.27 242 2468
751.21 Cystic kidney disease congenital anomalies Both 0.3516 0.966 0.897,1.04 799 7929 0.4571 0.972 0.903,1.05 775 7776
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.0631 1.12 0.994,1.27 251 2506 0.05495 1.13 0.998,1.27 242 2468
751.3 Obstructive genitourinary defect congenital anomalies Both 0.7096 1.03 0.878,1.21 157 1560 0.7161 1.03 0.877,1.21 155 1526
752 Nervous system congenital anomalies congenital anomalies Both 0.2799 1.04 0.97,1.11 908 9073 0.5483 1.05 0.904,1.21 198 1963
752.1 Neural tube defects congenital anomalies Both 0.2506 1.04 0.97,1.13 728 7277 0.1455 1.14 0.957,1.35 140 1411
752.11 Spina bifida congenital anomalies Both 0.1042 1.15 0.972,1.36 144 1440 0.1455 1.14 0.957,1.35 140 1411
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.7261 1.03 0.887,1.19 201 2010 0.5483 1.05 0.904,1.21 198 1963
753 Congenital anomalies of the eye congenital anomalies Both 0.5035 0.943 0.795,1.12 146 1451 0.5152 0.944 0.793,1.12 143 1420
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.3793 0.971 0.91,1.04 1006 10049 0.4159 1.04 0.946,1.14 464 4565
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.6966 0.963 0.798,1.16 116 1155 0.4236 0.924 0.761,1.12 114 1116
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.4753 1.03 0.942,1.14 470 4675 0.4159 1.04 0.946,1.14 464 4565
755 Congenital anomalies of limbs congenital anomalies Both 0.881 1.01 0.927,1.09 625 6237 0.1758 1.12 0.952,1.31 150 1489
755.1 Congenital deformities of feet congenital anomalies Both 0.5093 0.962 0.856,1.08 315 3138 0.5093 0.961 0.856,1.08 311 3077
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.3048 1.15 0.877,1.52 58 567 0.2606 1.17 0.889,1.54 56 553
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.514 1.04 0.92,1.18 258 2580 0.1758 1.12 0.952,1.31 150 1489
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.1941 1.11 0.948,1.3 152 1520 0.1758 1.12 0.952,1.31 150 1489
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.2698 1.04 0.973,1.1 1021 10203 0.06457 1.07 0.996,1.15 730 7245
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.6397 0.938 0.717,1.23 55 527 0.597 0.93 0.71,1.22 55 515
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.1629 1.2 0.928,1.56 56 524 0.2393 1.17 0.9,1.53 54 516
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.6823 0.973 0.855,1.11 246 2459 0.8551 0.988 0.868,1.12 244 2404
756.5 Congenital osteodystrophies congenital anomalies Both 0.08511 1.07 0.991,1.15 743 7419 0.06457 1.07 0.996,1.15 730 7245
757 Congenital anomalies of the integument congenital anomalies Both 0.2564 0.93 0.821,1.05 283 2820 0.2917 0.934 0.823,1.06 275 2765
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.1503 1.13 0.956,1.34 134 1334 0.2588 1.13 0.915,1.39 88 893
758.1 Chromosomal anomalies congenital anomalies Both 0.1479 1.16 0.948,1.42 91 910 0.2588 1.13 0.915,1.39 88 893
759 Other and unspecified congenital anomalies congenital anomalies Both 0.3664 0.958 0.872,1.05 498 4964 0.8017 0.988 0.898,1.09 471 4852
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.7499 0.959 0.743,1.24 57 567 ,
760 Back pain symptoms Both 0.7079 1.0 0.983,1.03 12687 25663 0.5675 1.01 0.985,1.03 12436 25116
761 Cervicalgia symptoms Both 0.1409 1.02 0.993,1.05 5134 32829 0.1923 1.02 0.99,1.05 5013 32155
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.7638 0.994 0.957,1.03 2927 27356 0.743 0.994 0.956,1.03 2869 26773
764 Sciatica symptoms Both 0.7745 0.994 0.955,1.04 2623 25291 0.7798 0.994 0.954,1.04 2570 24739
765 Cervical radiculitis symptoms Both 0.7295 0.99 0.937,1.05 1401 13966 0.8035 0.993 0.939,1.05 1379 13658
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.7551 0.995 0.962,1.03 4004 31031 0.7816 0.995 0.963,1.03 3929 30371
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.1517 1.18 0.942,1.47 85 835 0.13 1.19 0.95,1.49 84 817
769 Nonallopathic lesions NEC symptoms Both 0.05888 0.936 0.873,1.0 923 9183 0.05248 0.933 0.871,1.0 906 8969
770 Myalgia and myositis unspecified symptoms Both 0.2618 1.02 0.986,1.05 4324 27592 0.1754 1.02 0.99,1.06 4230 26979
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.3273 0.983 0.949,1.02 3638 29710 0.04898 1.08 1.0,1.16 758 7689
771.1 Swelling of limb symptoms Both 0.9354 1.0 0.97,1.03 4511 29862 0.9016 1.0 0.971,1.03 4424 29227
771.2 Cramp of limb symptoms Both 0.04074 1.08 1.0,1.16 791 7856 0.04898 1.08 1.0,1.16 758 7689
772 Symptoms of the muscles symptoms Both 0.02455 1.06 1.01,1.12 1549 15345 0.5458 0.967 0.866,1.08 367 3672
772.1 Muscular wasting and disuse atrophy symptoms Both 0.7691 1.02 0.907,1.14 320 3187 0.9183 1.01 0.896,1.13 314 3140
772.2 Spasm of muscle symptoms Both 0.3631 1.02 0.974,1.07 1780 17782 0.2858 1.03 0.978,1.08 1739 17397
772.3 Muscle weakness symptoms Both 0.7096 1.01 0.966,1.05 2339 22770 0.5794 1.01 0.97,1.06 2286 22313
772.4 Rhabdomyolysis symptoms Both 0.9376 1.01 0.833,1.22 117 1170 0.9638 1.0 0.829,1.22 116 1161
772.6 Facial weakness symptoms Both 0.7129 0.98 0.88,1.09 377 3746 0.5458 0.967 0.866,1.08 367 3672
773 Pain in limb symptoms Both 0.7362 1.0 0.982,1.03 11393 26958 0.4775 1.01 0.986,1.03 11198 26356
780 Hypothermia/Chills symptoms Both 0.2924 0.937 0.83,1.06 307 3069 0.3258 0.941 0.833,1.06 300 3006
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.8091 1.01 0.958,1.06 1767 17206 0.9036 0.987 0.796,1.22 90 872
781.1 Loss of height symptoms Both 0.9016 0.987 0.797,1.22 91 890 0.9036 0.987 0.796,1.22 90 872
782.3 Edema symptoms Both 0.6442 1.01 0.976,1.04 4591 30849 0.6412 1.01 0.976,1.04 4489 30195
782.6 Pallor and flushing symptoms Both 0.0631 1.08 0.996,1.16 679 6769 0.05129 1.08 1.0,1.17 662 6586
783 Fever of unknown origin symptoms Both 0.389 1.01 0.983,1.05 4616 33703 0.9419 1.0 0.882,1.14 245 2414
783.1 Postprocedural fever symptoms Both 0.811 1.02 0.893,1.16 248 2473 0.9419 1.0 0.882,1.14 245 2414
785 Abdominal pain symptoms Both 0.1493 1.02 0.994,1.04 13257 25098 0.0871 1.02 0.997,1.04 13009 24548
788 Syncope and collapse symptoms Both 0.1086 1.03 0.993,1.07 3017 29114 0.07413 1.03 0.997,1.07 2945 28510
789 Nausea and vomiting symptoms Both 0.3846 1.01 0.987,1.04 8497 29838 0.9484 0.997 0.916,1.09 615 6191
789.1 Persistent vomiting symptoms Both 0.8128 0.99 0.911,1.08 634 6330 0.9484 0.997 0.916,1.09 615 6191
790 Nonspecific findings on examination of blood symptoms Both 0.2735 1.03 0.979,1.08 1740 17356 0.1629 0.867 0.709,1.06 121 1209
790.1 Elevated sedimentation rate symptoms Both 0.7129 1.03 0.878,1.21 158 1580 0.5395 1.05 0.896,1.23 154 1536
790.6 Other abnormal blood chemistry symptoms Both 0.0631 1.03 0.998,1.06 4849 31554 0.03715 1.03 1.0,1.07 4743 30890
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.5408 0.955 0.825,1.11 204 2026 0.6353 0.965 0.833,1.12 202 1977
790.9 Abnormal arterial blood gases symptoms Both 0.1045 0.847 0.694,1.03 123 1230 0.1629 0.867 0.709,1.06 121 1209
791 Gangrene symptoms Both 0.6918 0.972 0.843,1.12 212 2104 0.7727 0.979 0.849,1.13 210 2066
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.2518 0.973 0.929,1.02 2171 11972 0.6592 1.02 0.946,1.09 823 7580
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.673 1.02 0.946,1.09 841 7806 0.6592 1.02 0.946,1.09 823 7580
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.2244 1.05 0.968,1.15 588 5848 0.0537 1.05 0.999,1.1 1621 16254
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.02884 1.06 1.01,1.11 1661 16601 0.0537 1.05 0.999,1.1 1621 16254
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.6966 1.02 0.925,1.12 433 4330 0.6339 1.02 0.928,1.13 419 4248
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.4477 0.98 0.931,1.03 1632 15619 0.5023 0.946 0.805,1.11 164 1615
795.8 Abnormal tumor markers symptoms Both 0.2203 1.03 0.981,1.08 1698 13664 0.5023 0.946 0.805,1.11 164 1615
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.5521 0.952 0.811,1.12 167 1662 0.5023 0.946 0.805,1.11 164 1615
796 Elevated prostate specific antigen [PSA] symptoms Male 0.3076 1.03 0.975,1.08 1700 8294 0.2133 1.03 0.981,1.09 1680 8161
797 Shock symptoms Both 0.05129 1.1 1.0,1.21 445 4446 0.3443 1.07 0.927,1.24 180 1787
797.1 Cardiogenic shock symptoms Both 0.2944 1.08 0.934,1.25 183 1822 0.3443 1.07 0.927,1.24 180 1787
798 Malaise and fatigue symptoms Both 0.1483 1.02 0.994,1.04 8867 29476 0.3837 1.03 0.969,1.08 1306 13088
798.1 Chronic fatigue syndrome symptoms Both 0.3013 1.03 0.974,1.09 1349 13380 0.3837 1.03 0.969,1.08 1306 13088
799 Debility unspecified symptoms Both 0.3155 1.03 0.976,1.08 1672 16007 0.2958 1.03 0.977,1.08 1645 15674
800 Fracture of lower limb injuries & poisonings Both 0.7656 1.01 0.961,1.06 1879 18684 0.8974 1.01 0.895,1.13 289 2842
800.1 Fracture of neck of femur injuries & poisonings Both 0.1253 0.922 0.831,1.02 409 4028 0.157 0.928 0.836,1.03 405 3941
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.6095 0.977 0.893,1.07 539 5364 0.6622 0.98 0.895,1.07 532 5254
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.5957 0.98 0.909,1.06 744 7420 0.7047 0.985 0.914,1.06 734 7282
800.4 Fracture of patella injuries & poisonings Both 0.871 1.01 0.898,1.14 293 2904 0.8974 1.01 0.895,1.13 289 2842
801 Fracture of ankle and foot injuries & poisonings Both 0.9036 1.0 0.956,1.05 1804 17960 0.4819 1.02 0.958,1.1 905 8902
801.1 Fracture of foot injuries & poisonings Both 0.5458 1.02 0.955,1.09 913 9098 0.4819 1.02 0.958,1.1 905 8902
802 Fracture of pelvis injuries & poisonings Both 0.6012 1.03 0.921,1.15 321 3192 0.5272 1.04 0.926,1.16 319 3127
803 Fracture of upper limb injuries & poisonings Both 0.1816 1.04 0.984,1.09 1644 16288 0.1 1.09 0.985,1.2 413 4103
803.1 Fracture of humerus injuries & poisonings Both 0.778 0.988 0.907,1.08 592 5913 0.9727 1.0 0.919,1.09 584 5769
803.2 Fracture of radius and ulna injuries & poisonings Both 0.1303 1.05 0.985,1.13 899 8929 0.369 1.06 0.932,1.21 244 2417
803.21 Colles' fracture injuries & poisonings Both 0.492 1.05 0.919,1.19 248 2475 0.369 1.06 0.932,1.21 244 2417
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.1153 1.08 0.981,1.19 419 4190 0.1 1.09 0.985,1.2 413 4103
804 Fracture of hand or wrist injuries & poisonings Both 0.1445 1.04 0.986,1.1 1272 12504 0.1422 1.04 0.986,1.11 1246 12227
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.3828 1.03 0.966,1.09 1082 10755 0.3606 1.03 0.967,1.1 1061 10548
807 Fracture of ribs injuries & poisonings Both 0.1312 1.07 0.98,1.16 543 5428 0.1227 1.07 0.982,1.17 530 5307
809 Fracture of unspecified bones injuries & poisonings Both 0.05754 1.04 0.999,1.08 2426 23282 0.04074 1.04 1.0,1.09 2393 22764
817 Concussion injuries & poisonings Both 0.4457 0.971 0.902,1.05 771 7696 0.597 0.98 0.909,1.06 756 7528
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.3784 1.06 0.93,1.21 240 2380 0.1614 1.17 0.94,1.45 84 826
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.492 1.08 0.863,1.36 74 740 0.4699 1.09 0.866,1.36 74 720
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.1706 1.16 0.936,1.45 84 837 0.1614 1.17 0.94,1.45 84 826
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.7852 0.993 0.946,1.04 1782 17605 0.6792 0.99 0.942,1.04 1753 17249
830 Dislocation injuries & poisonings Both 0.7396 1.01 0.97,1.04 3129 28682 0.6855 1.01 0.971,1.05 3084 28043
835 Internal derangement of knee injuries & poisonings Both 0.0631 1.05 0.998,1.1 1774 17453 0.03467 1.05 1.0,1.11 1750 17093
836 Traumatic arthropathy injuries & poisonings Both 0.3936 1.04 0.946,1.15 423 4213 0.3199 1.05 0.952,1.16 417 4136
840 Sprains and strains injuries & poisonings Both 0.6412 1.01 0.979,1.03 6106 31582 0.2421 1.03 0.983,1.07 2232 19072
840.1 Muscle/tendon sprain injuries & poisonings Both 0.4385 1.04 0.943,1.15 429 4269 0.4395 1.04 0.942,1.15 421 4182
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.865 1.0 0.95,1.06 1343 13394 0.7674 1.01 0.953,1.07 1321 13116
840.3 Joint/ligament sprain injuries & poisonings Both 0.3373 1.02 0.978,1.07 2261 19530 0.2421 1.03 0.983,1.07 2232 19072
841 Sprains and strains of back and neck injuries & poisonings Both 0.1355 1.05 0.986,1.11 1175 11729 0.173 1.04 0.982,1.11 1150 11430
842 Other sprains and strains injuries & poisonings Both 0.1183 1.05 0.988,1.12 1079 10729 0.06457 1.06 0.997,1.13 1060 10502
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.3206 1.02 0.977,1.07 1807 18037 0.2099 1.03 0.983,1.08 1768 17626
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.8851 0.995 0.924,1.07 797 7958 0.9462 0.997 0.926,1.07 784 7809
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.3656 1.05 0.947,1.16 398 3977 0.3467 1.05 0.949,1.16 391 3894
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.5572 1.02 0.964,1.07 1537 15333 0.537 1.02 0.965,1.07 1515 15015
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.5861 0.964 0.846,1.1 254 2540 0.7943 0.983 0.862,1.12 251 2493
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.9727 1.0 0.882,1.14 262 2617 0.7603 0.98 0.861,1.12 256 2566
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.9099 1.0 0.945,1.07 1196 11925 0.955 1.0 0.943,1.06 1178 11636
858 Complication of internal orthopedic device injuries & poisonings Both 0.2799 0.974 0.929,1.02 1892 18846 0.2704 0.974 0.928,1.02 1873 18454
859 Complication due to other implant and internal device injuries & poisonings Both 0.3475 0.977 0.931,1.03 1820 18191 0.3565 0.977 0.93,1.03 1790 17766
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.8185 0.996 0.961,1.03 3389 30552 0.4688 1.07 0.894,1.28 116 1135
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.7379 0.971 0.82,1.15 156 1551 0.8511 0.984 0.83,1.17 154 1520
870.2 Open wound of ear injuries & poisonings Both 0.8017 0.976 0.806,1.18 114 1131 0.9616 0.995 0.822,1.21 111 1111
870.3 Other open wound of head and face injuries & poisonings Both 0.6266 0.984 0.924,1.05 1064 10560 0.7063 0.988 0.927,1.05 1046 10357
870.4 Open wound of nose and sinus injuries & poisonings Both 0.9683 1.0 0.855,1.18 168 1667 0.9204 1.01 0.86,1.18 167 1630
870.5 Open wound of lip and mouth injuries & poisonings Both 0.1866 1.09 0.957,1.25 230 2293 0.1845 1.09 0.958,1.25 228 2252
870.6 Open wound of neck injuries & poisonings Both 0.6194 1.04 0.894,1.21 184 1833 0.7482 1.03 0.88,1.19 179 1802
870.8 Open wound of genital organs injuries & poisonings Both 0.5808 1.05 0.879,1.26 117 1170 0.4688 1.07 0.894,1.28 116 1135
871 Open wounds of extremities injuries & poisonings Both 0.1183 1.03 0.992,1.07 2705 26585 0.5248 1.05 0.904,1.22 191 1862
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.7031 0.981 0.891,1.08 438 4378 0.8017 0.988 0.896,1.09 428 4282
871.2 Open wound of finger(s) injuries & poisonings Both 0.07586 1.07 0.993,1.15 731 7291 0.09333 1.07 0.99,1.15 721 7149
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.1247 0.913 0.814,1.03 331 3277 0.1675 0.922 0.821,1.03 330 3203
871.4 Open wound of toe(s) injuries & poisonings Both 0.5585 1.05 0.9,1.22 191 1901 0.5248 1.05 0.904,1.22 191 1862
872 Traumatic amputation injuries & poisonings Both 0.4246 0.959 0.867,1.06 415 4129 0.3954 0.957 0.864,1.06 413 4050
873 Broken tooth injuries & poisonings Both 0.6383 0.96 0.811,1.14 148 1471 0.5821 0.953 0.802,1.13 143 1439
874 Complication of amputation stump injuries & poisonings Both 0.3192 0.907 0.75,1.1 122 1220 0.3251 0.909 0.752,1.1 122 1200
875 Non-healing surgical wound injuries & poisonings Both 0.7745 1.01 0.924,1.11 495 4950 0.7656 1.01 0.925,1.11 489 4848
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.5821 0.978 0.902,1.06 669 6680 0.6776 0.983 0.906,1.07 652 6528
907 Injuries to the nervous system injuries & poisonings Both 0.6012 0.982 0.916,1.05 888 8852 0.5715 0.98 0.914,1.05 872 8677
910 Superficial injury, infected injuries & poisonings Both 0.2046 0.866 0.693,1.08 89 887 0.2061 0.867 0.695,1.08 89 870
911 Blister injuries & poisonings Both 0.4797 1.06 0.908,1.23 185 1838 0.415 1.07 0.915,1.24 182 1803
912 Insect bite injuries & poisonings Both 0.7178 1.02 0.912,1.14 321 3207 0.6653 1.03 0.914,1.15 313 3139
913 Toxic effect of venom injuries & poisonings Both 0.1618 1.09 0.965,1.24 247 2461 0.1455 1.1 0.968,1.24 244 2403
915 Superficial injury without mention of infection injuries & poisonings Both 0.4416 1.02 0.975,1.06 2368 23457 0.2877 1.02 0.981,1.07 2336 22957
916 Contusion injuries & poisonings Both 0.877 1.0 0.967,1.04 3199 30228 0.7745 1.01 0.969,1.04 3136 29590
930 Allergic reaction to food injuries & poisonings Both 0.4457 1.03 0.95,1.12 597 5953 0.3573 1.04 0.956,1.13 584 5823
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.3963 1.04 0.952,1.13 530 5290 0.2938 1.05 0.96,1.14 515 5160
938 Dermatitis due to solar radiation injuries & poisonings Both 0.03162 1.04 1.0,1.07 4197 24407 0.02239 1.04 1.01,1.08 3894 23494
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.5559 1.05 0.901,1.21 164 1640 0.547 1.05 0.902,1.22 161 1602
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.01905 1.04 1.01,1.08 4001 24007 0.02239 1.04 1.01,1.08 3894 23494
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.4467 1.07 0.9,1.27 140 1400 0.4797 1.07 0.894,1.27 135 1370
942 Infusion and transfusion reaction injuries & poisonings Both 0.1496 1.1 0.965,1.26 221 2205 0.1374 1.11 0.968,1.26 219 2170
946 Anaphylactic shock NOS injuries & poisonings Both 0.2477 1.06 0.959,1.17 385 3830 0.1589 1.08 0.972,1.19 372 3737
947 Urticaria injuries & poisonings Both 0.7907 0.991 0.925,1.06 889 8845 0.8337 1.01 0.94,1.08 860 8611
949 Allergies, other injuries & poisonings Both 0.4198 1.01 0.983,1.04 5269 26807 0.3112 1.02 0.985,1.05 5128 26257
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.4875 0.964 0.87,1.07 419 4176 0.4256 0.959 0.864,1.06 412 4104
957 Injury to other and unspecified nerves injuries & poisonings Both 0.2366 0.888 0.73,1.08 116 1150 0.1563 0.866 0.71,1.06 114 1128
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.5346 0.98 0.92,1.04 1073 10721 0.4385 1.09 0.883,1.33 90 895
958.1 Postoperative shock injuries & poisonings Both 0.5248 0.942 0.785,1.13 133 1325 0.5998 0.952 0.792,1.14 131 1299
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.3412 1.1 0.9,1.35 92 911 0.4385 1.09 0.883,1.33 90 895
960 Poisoning by antibiotics injuries & poisonings Both 0.2891 1.02 0.98,1.07 2108 18753 0.6653 1.01 0.958,1.07 1379 13538
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.1469 1.12 0.96,1.32 158 1552 0.1535 1.12 0.958,1.32 155 1510
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.6138 1.01 0.96,1.07 1414 13864 0.6653 1.01 0.958,1.07 1379 13538
961 Poisoning by other anti-infectives injuries & poisonings Both 0.7516 0.985 0.897,1.08 470 4694 0.0955 1.06 0.99,1.13 922 8960
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.1294 1.05 0.985,1.12 939 9190 0.0955 1.06 0.99,1.13 922 8960
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.9376 1.0 0.92,1.09 561 5601 0.9016 0.993 0.883,1.12 297 2969
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.6252 0.971 0.861,1.09 308 3069 0.6095 0.969 0.859,1.09 299 3008
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.7161 0.979 0.871,1.1 305 3029 0.9016 0.993 0.883,1.12 297 2969
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.01259 1.06 1.01,1.11 2031 19919 0.00871 1.06 1.02,1.11 1944 19066
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.00912 1.06 1.02,1.11 1980 19507 0.00871 1.06 1.02,1.11 1944 19066
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.06457 0.917 0.837,1.01 538 5360 0.2014 0.94 0.856,1.03 495 4977
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.1253 0.929 0.846,1.02 509 5070 0.2014 0.94 0.856,1.03 495 4977
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.2761 0.959 0.888,1.03 753 7525 0.1355 0.846 0.679,1.05 97 953
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.3573 0.973 0.918,1.03 1305 12848 0.3724 0.974 0.918,1.03 1276 12555
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.114 0.838 0.672,1.04 98 967 0.1355 0.846 0.679,1.05 97 953
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.5728 1.06 0.86,1.31 86 850 0.5495 1.07 0.864,1.32 86 839
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.871 0.995 0.932,1.06 1000 9986 0.9886 1.0 0.935,1.07 964 9750
969 Poisoning by psychotropic agents injuries & poisonings Both 0.9141 0.992 0.866,1.14 234 2331 1.0 1.0 0.872,1.15 233 2284
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.2009 1.19 0.91,1.57 56 546 0.1841 1.2 0.916,1.58 56 535
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.8551 1.01 0.885,1.16 228 2269 0.3221 0.89 0.706,1.12 83 844
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.7709 0.963 0.748,1.24 66 637 0.7674 0.963 0.748,1.24 66 630
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.4853 0.923 0.737,1.16 86 860 0.3221 0.89 0.706,1.12 83 844
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.4188 1.09 0.884,1.35 90 896 0.4426 1.09 0.879,1.34 89 881
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.4753 1.09 0.856,1.4 69 686 0.5321 1.08 0.847,1.38 68 668
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.4667 1.1 0.851,1.42 60 600 0.6026 1.07 0.825,1.39 58 593
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.6138 1.01 0.962,1.07 1565 14843 0.5572 1.02 0.964,1.07 1532 14500
979 Adverse drug events and drug allergies injuries & poisonings Both 0.006607 1.06 1.02,1.11 2116 20636 0.01122 1.06 1.01,1.11 2062 20173
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.9333 1.01 0.81,1.26 91 904 0.879 1.02 0.814,1.27 89 881
990 Effects radiation NOS injuries & poisonings Both 0.2438 1.02 0.984,1.07 2707 23906 0.3119 1.02 0.981,1.06 2592 23452
994 Sepsis and SIRS injuries & poisonings Both 0.6067 1.01 0.964,1.06 1724 17160 0.2992 1.05 0.958,1.15 479 4742
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.867 0.989 0.866,1.13 248 2472 0.9204 1.01 0.882,1.15 244 2420
994.2 Sepsis injuries & poisonings Both 0.5623 1.02 0.965,1.07 1636 16281 0.2992 1.05 0.958,1.15 479 4742
994.21 Septic shock injuries & poisonings Both 0.342 1.05 0.954,1.15 484 4840 0.2992 1.05 0.958,1.15 479 4742
1000 Burns injuries & poisonings Both 0.8035 0.99 0.913,1.07 638 6350 0.8318 0.991 0.914,1.08 629 6200
1001 Foreign body injury injuries & poisonings Both 0.5176 0.986 0.945,1.03 2372 22762 0.3664 0.98 0.939,1.02 2323 22337
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.8433 0.997 0.967,1.03 4830 32603 0.9931 1.0 0.97,1.03 4727 31929
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.778 0.991 0.933,1.05 1136 11344 0.8128 0.993 0.934,1.06 1122 11112
1005 Other symptoms injuries & poisonings Both 0.6223 0.994 0.969,1.02 7724 30626 0.6266 0.994 0.969,1.02 7581 29972
1006 Crushing injury injuries & poisonings Both 0.2649 1.08 0.947,1.22 245 2437 0.2667 1.08 0.946,1.22 243 2387
1007 Injury to blood vessels injuries & poisonings Both 0.05012 0.901 0.811,1.0 411 4106 0.05248 0.901 0.811,1.0 408 4027
1008 Crushing or internal injury to organs injuries & poisonings Both 0.5395 1.02 0.955,1.09 934 9331 0.5875 1.02 0.952,1.09 919 9144
1009 Injury, NOS injuries & poisonings Both 0.1365 1.02 0.994,1.04 9284 29063 0.07079 1.02 0.998,1.05 9137 28412
1010 Other tests injuries & poisonings Both 0.104 1.02 0.997,1.04 19027 19331 0.06607 1.02 0.999,1.04 18631 18930
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.3373 0.986 0.959,1.01 5922 32336 0.3273 0.986 0.959,1.01 5813 31648
1012 Late effect injuries & poisonings Both 0.863 0.994 0.923,1.07 792 7909 0.8954 0.995 0.923,1.07 770 7740
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.6039 1.01 0.97,1.05 2459 23709 0.5768 1.01 0.971,1.06 2411 23228
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3639 1.07 0.924,1.24 177 1770 0.3954 1.07 0.92,1.23 175 1731
1015 Effects of other external causes injuries & poisonings Both 0.4446 0.989 0.961,1.02 5744 32595 0.4842 0.99 0.962,1.02 5641 31901
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.4159 0.982 0.94,1.03 2208 21537 0.4217 0.982 0.939,1.03 2172 21101
1100 Family history injuries & poisonings Both 0.5483 0.959 0.835,1.1 222 2220 0.5794 0.961 0.836,1.11 213 2154
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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