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MGI PRS for Cancer of brain(191.11) based on GWAS Catalog (2019-05-03)
GWAS reference: 22472174;26424050;28346443 GWAS source: GWAS Catalog (2019-05-03) PRS method: P&T
PRSweb LD reference: MGI GWAS phenotype: Glioblastoma PRSweb date: 2020-06-20
GWAS ID: GWAS_Catalog_r2019-05-03_X191.11 GWAS URL: https://www.ebi.ac.uk/gwas Genome build: GRCh37/hg19
PRS tuning parameter: P<=3.16e-09 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.7998 0.995 0.953,1.04 2317 23065 0.3304 0.967 0.902,1.04 907 9123
008.5 Bacterial enteritis infectious diseases Both 0.673 0.987 0.926,1.05 1090 10875 0.6368 0.983 0.916,1.06 867 8746
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.5572 0.979 0.913,1.05 896 8939 0.6368 0.983 0.916,1.06 867 8746
008.6 Viral Enteritis infectious diseases Both 0.8531 1.01 0.926,1.1 590 5900 0.7816 1.01 0.929,1.1 575 5768
010 Tuberculosis infectious diseases Both 0.2466 1.09 0.942,1.26 195 1948 0.8472 1.0 0.982,1.02 18538 18916
031 Diseases due to other mycobacteria infectious diseases Both 0.4977 0.92 0.724,1.17 73 722 0.7709 0.964 0.753,1.23 70 710
038 Septicemia infectious diseases Both 0.3972 0.98 0.937,1.03 2043 20052 0.6138 0.983 0.918,1.05 923 9269
038.1 Gram negative septicemia infectious diseases Both 0.208 1.06 0.966,1.17 459 4559 0.1766 1.07 0.97,1.18 436 4449
038.2 Gram positive septicemia infectious diseases Both 0.4457 1.06 0.912,1.23 184 1840 0.5689 1.05 0.896,1.22 175 1798
038.3 Bacteremia infectious diseases Both 0.7178 0.988 0.924,1.06 955 9489 0.6138 0.983 0.918,1.05 923 9269
041 Bacterial infection NOS infectious diseases Both 0.1384 0.977 0.947,1.01 4641 32299 0.1552 1.1 0.964,1.26 225 2208
041.1 Staphylococcus infections infectious diseases Both 0.25 0.968 0.916,1.02 1390 13828 0.871 0.993 0.914,1.08 617 6240
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.455 0.971 0.899,1.05 714 7071 0.3811 0.965 0.891,1.04 675 6924
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.7656 0.988 0.911,1.07 639 6376 0.871 0.993 0.914,1.08 617 6240
041.2 Streptococcus infection infectious diseases Both 0.9268 1.0 0.947,1.06 1316 13131 0.7551 1.02 0.886,1.18 199 2001
041.21 Rheumatic fever / chorea infectious diseases Both 0.7047 1.03 0.892,1.19 205 2047 0.7551 1.02 0.886,1.18 199 2001
041.4 E. coli infectious diseases Both 0.9863 1.0 0.936,1.07 949 9462 0.9016 0.996 0.93,1.07 907 9256
041.8 H. pylori infectious diseases Both 0.5598 0.958 0.83,1.11 190 1892 0.5675 0.959 0.83,1.11 188 1856
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.105 1.12 0.977,1.28 228 2265 0.1552 1.1 0.964,1.26 225 2208
053 Herpes zoster infectious diseases Both 0.4775 1.02 0.963,1.08 1184 11746 0.5808 1.05 0.891,1.23 160 1610
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.7727 1.02 0.874,1.2 166 1655 0.5808 1.05 0.891,1.23 160 1610
054 Herpes simplex infectious diseases Both 0.6918 1.01 0.955,1.07 1235 12278 0.5534 1.02 0.96,1.08 1203 12002
070 Viral hepatitis infectious diseases Both 0.8017 0.99 0.915,1.07 661 6584 0.5636 1.02 0.953,1.09 894 9018
070.1 Viral hepatitis A infectious diseases Both 0.9683 0.995 0.772,1.28 67 660 0.9795 1.0 0.778,1.29 66 649
070.2 Viral hepatitis B infectious diseases Both 0.02512 1.2 1.02,1.4 162 1620 0.02239 1.2 1.03,1.41 160 1572
070.3 Viral hepatitis C infectious diseases Both 0.278 0.948 0.86,1.04 439 4366 0.2649 0.946 0.857,1.04 426 4268
070.4 Chronic hepatitis infectious diseases Both 0.8204 1.02 0.861,1.21 161 1610 0.9204 1.01 0.849,1.2 155 1570
070.9 Hepatitis NOS infectious diseases Both 0.5861 1.02 0.953,1.09 924 9231 0.5636 1.02 0.953,1.09 894 9018
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.8318 0.98 0.813,1.18 122 1220 0.5768 1.06 0.864,1.3 94 926
071.1 HIV infection, symptomatic infectious diseases Both 0.695 1.04 0.85,1.28 95 950 0.5768 1.06 0.864,1.3 94 926
078 Viral warts & HPV infectious diseases Both 0.7798 0.994 0.955,1.04 2651 24185 0.8872 0.997 0.957,1.04 2602 23628
079 Viral infection infectious diseases Both 0.2742 1.02 0.987,1.05 5061 29504 0.0955 0.928 0.851,1.01 571 5576
079.1 Varicella infection infectious diseases Both 0.007079 1.05 1.01,1.09 2940 25647 0.006166 1.06 1.02,1.1 2857 25057
079.2 Infectious mononucleosis infectious diseases Both 0.3388 0.932 0.807,1.08 213 2093 0.4036 0.94 0.812,1.09 210 2031
079.9 Viremia, NOS infectious diseases Both 0.0955 0.929 0.852,1.01 579 5713 0.0955 0.928 0.851,1.01 571 5576
080 Postoperative infection infectious diseases Both 0.2985 0.979 0.94,1.02 2586 25769 0.2858 0.978 0.938,1.02 2501 25190
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.241 0.967 0.915,1.02 1364 13616 0.4276 0.977 0.923,1.03 1317 13318
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.5916 0.979 0.906,1.06 700 6990 0.6966 0.985 0.911,1.06 685 6824
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.1371 1.03 0.99,1.08 2379 23308 0.2438 0.92 0.799,1.06 216 2178
110.1 Dermatophytosis infectious diseases Both 0.6152 1.01 0.967,1.06 2164 21163 0.9886 1.0 0.917,1.09 561 5539
110.11 Dermatophytosis of nail infectious diseases Both 0.875 1.0 0.948,1.06 1264 12489 0.8872 1.0 0.947,1.06 1235 12195
110.12 Althete's foot infectious diseases Both 0.3802 1.04 0.955,1.13 593 5884 0.3846 1.04 0.954,1.13 581 5745
110.13 Dermatophytosis of the body infectious diseases Both 0.9954 1.0 0.916,1.09 570 5682 0.9886 1.0 0.917,1.09 561 5539
110.2 Dermatomycoses infectious diseases Both 0.008318 1.18 1.04,1.33 283 2812 0.005129 1.19 1.05,1.35 275 2738
112 Candidiasis infectious diseases Both 0.7551 1.01 0.968,1.05 2931 25310 0.342 0.958 0.877,1.05 537 5314
112.3 Candidiasis of skin and nails infectious diseases Both 0.3963 0.963 0.883,1.05 546 5450 0.342 0.958 0.877,1.05 537 5314
117 Mycoses infectious diseases Both 0.004898 1.14 1.04,1.25 494 4925 0.06918 1.19 0.986,1.45 101 1021
117.1 Histoplasmosis infectious diseases Both 0.2799 1.15 0.892,1.48 66 660 0.4315 1.11 0.858,1.43 65 644
117.4 Aspergillosis infectious diseases Both 0.04266 1.21 1.01,1.46 105 1045 0.06918 1.19 0.986,1.45 101 1021
130 Spirochetal infection infectious diseases Both 0.6966 1.04 0.855,1.26 118 1177 0.6109 1.06 0.845,1.33 84 844
130.1 Lyme disease infectious diseases Both 0.6295 1.06 0.845,1.32 86 860 0.6109 1.06 0.845,1.33 84 844
132 Infestation (lice, mites) infectious diseases Both 0.08913 1.16 0.978,1.37 146 1460 0.123 1.14 0.964,1.36 144 1427
134 Helminthiases infectious diseases Both 0.3499 1.13 0.877,1.45 54 540 ,
136 Other infectious and parasitic diseases infectious diseases Both 0.8147 1.0 0.964,1.05 2438 24314 0.6561 1.01 0.968,1.05 2371 23747
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.9638 0.999 0.941,1.06 1166 11657 0.877 1.0 0.946,1.07 1134 11379
145 Cancer of mouth neoplasms Both 0.1009 1.05 0.99,1.12 1182 11759 0.4943 0.947 0.811,1.11 172 1685
145.1 Cancer of lip neoplasms Both 0.02884 1.32 1.03,1.7 69 690 0.05754 1.28 0.993,1.65 67 664
145.2 Cancer of tongue neoplasms Both 0.3656 1.04 0.955,1.13 550 5486 0.2518 1.05 0.964,1.15 542 5363
145.3 Cancer of major salivary glands neoplasms Both 0.8472 1.01 0.9,1.14 310 3093 0.4943 1.04 0.924,1.18 280 3033
145.4 Cancer of the gums neoplasms Both 0.5636 1.05 0.888,1.24 143 1419 0.5309 1.06 0.891,1.25 141 1390
145.5 Cancer of the mouth floor neoplasms Both 0.4009 0.936 0.802,1.09 173 1723 0.4943 0.947 0.811,1.11 172 1685
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.526 0.98 0.921,1.04 1124 11202 0.6353 0.962 0.82,1.13 172 2018
149.1 Cancer of oropharynx neoplasms Both 0.6353 0.971 0.862,1.09 291 2892 0.8974 0.992 0.879,1.12 283 2825
149.2 Cancer of nasopharynx neoplasms Both 0.8511 0.979 0.782,1.22 87 855 0.6471 0.946 0.744,1.2 75 837
149.3 Cancer of hypopharynx neoplasms Both 0.5297 1.08 0.856,1.35 68 680 0.5105 1.08 0.857,1.36 66 668
149.4 Cancer of larynx neoplasms Both 0.1521 1.08 0.971,1.21 332 3314 0.0955 1.1 0.983,1.23 325 3228
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.5321 1.03 0.94,1.13 505 5041 0.1963 1.06 0.969,1.17 479 4925
149.9 Cancer of of nasal cavities neoplasms Both 0.3281 0.93 0.803,1.08 208 2067 0.6353 0.962 0.82,1.13 172 2018
150 Cancer of esophagus neoplasms Both 0.3917 0.955 0.861,1.06 378 3776 0.3698 0.952 0.856,1.06 358 3674
151 Cancer of stomach neoplasms Both 0.6109 0.975 0.884,1.08 430 4292 0.5741 0.972 0.879,1.07 412 4186
153 Colorectal cancer neoplasms Both 0.673 0.987 0.93,1.05 1196 11882 0.6577 0.982 0.907,1.06 654 6508
153.2 Colon cancer neoplasms Both 0.5212 0.978 0.915,1.05 941 9327 0.4699 0.975 0.911,1.04 918 9093
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.5495 0.976 0.902,1.06 669 6663 0.6577 0.982 0.907,1.06 654 6508
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.5358 0.969 0.876,1.07 418 4180 0.6839 1.03 0.908,1.16 276 2793
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.8035 1.02 0.901,1.14 285 2850 0.6839 1.03 0.908,1.16 276 2793
157 Pancreatic cancer neoplasms Both 0.4613 0.963 0.872,1.06 430 4292 0.561 0.97 0.877,1.07 417 4208
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.5445 1.02 0.963,1.08 1369 13455 0.5035 1.02 0.964,1.08 1330 13153
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.9683 1.0 0.931,1.08 779 7785 0.2168 1.09 0.952,1.24 242 2484
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.1486 0.895 0.771,1.04 183 1830 0.2443 0.914 0.786,1.06 177 1780
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.0263 0.812 0.676,0.976 133 1330 0.03548 0.82 0.681,0.987 130 1305
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.2275 1.08 0.952,1.23 255 2550 0.2168 1.09 0.952,1.24 242 2484
164 Cancer of intrathoracic organs neoplasms Both 0.08128 1.18 0.98,1.43 111 1110 0.08318 1.19 0.977,1.44 103 1082
165 Cancer within the respiratory system neoplasms Both 0.1542 1.05 0.982,1.12 945 9436 0.195 1.05 0.976,1.13 805 8510
165.1 Cancer of bronchus; lung neoplasms Both 0.3396 1.03 0.965,1.11 874 8724 0.195 1.05 0.976,1.13 805 8510
170 Cancer of bone and connective tissue neoplasms Both 0.06761 1.05 0.996,1.11 1538 15304 0.1472 1.05 0.984,1.12 1019 10720
170.1 Bone cancer neoplasms Both 0.3243 1.04 0.961,1.13 668 6660 0.3945 1.04 0.953,1.13 573 6520
170.2 Cancer of connective tissue neoplasms Both 0.0537 1.06 0.999,1.13 1097 10941 0.1472 1.05 0.984,1.12 1019 10720
172 Skin cancer neoplasms Both 0.2851 1.01 0.988,1.04 7099 27878 0.3388 1.03 0.97,1.09 1179 10071
172.1 Melanomas of skin, dx or hx neoplasms Both 0.1294 1.03 0.991,1.07 2701 21867 0.2275 1.03 0.984,1.07 2520 21032
172.11 Melanomas of skin neoplasms Both 0.1435 1.03 0.99,1.07 2624 21526 0.2275 1.03 0.984,1.07 2520 21032
172.2 Other non-epithelial cancer of skin neoplasms Both 0.4571 1.01 0.982,1.04 5888 25669 0.2234 1.03 0.982,1.08 1865 14258
172.21 Basal cell carcinoma neoplasms Both 0.2818 1.02 0.983,1.06 2988 20068 0.4581 1.02 0.976,1.06 2900 19595
172.22 Squamous cell carcinoma neoplasms Both 0.1706 1.03 0.986,1.09 1917 14585 0.2234 1.03 0.982,1.08 1865 14258
172.3 Carcinoma in situ of skin neoplasms Both 0.369 1.03 0.968,1.09 1215 10290 0.3388 1.03 0.97,1.09 1179 10071
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.778 0.992 0.942,1.05 1575 15093 0.7925 0.993 0.941,1.05 1520 14757
174 Breast cancer neoplasms Both 0.6209 1.01 0.969,1.05 2694 13131 0.7447 0.976 0.843,1.13 196 2009
174.1 Breast cancer [female] neoplasms Female 0.6368 1.01 0.968,1.05 2605 12548 0.6039 1.01 0.968,1.06 2476 12242
174.11 Malignant neoplasm of female breast neoplasms Female 0.6792 1.01 0.967,1.05 2565 12510 0.6039 1.01 0.968,1.06 2476 12242
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.5834 0.961 0.833,1.11 206 2051 0.7447 0.976 0.843,1.13 196 2009
175 Acquired absence of breast neoplasms Female 0.2118 0.958 0.897,1.02 978 9172 0.2118 0.958 0.895,1.03 937 8964
180 Cervical cancer and dysplasia neoplasms Female 0.01318 0.926 0.871,0.984 1182 10494 0.0195 0.918 0.855,0.986 847 7692
180.1 Cervical cancer neoplasms Female 0.139 0.928 0.84,1.02 430 4300 0.04677 0.903 0.817,0.999 421 4187
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.01995 0.919 0.855,0.987 857 7886 0.0195 0.918 0.855,0.986 847 7692
182 Malignant neoplasm of uterus neoplasms Female 0.859 0.993 0.915,1.08 643 6390 0.695 0.984 0.905,1.07 631 6246
184 Cancer of other female genital organs neoplasms Female 0.3296 1.03 0.966,1.11 910 8957 0.881 0.993 0.907,1.09 516 5130
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.06761 1.09 0.994,1.2 491 4888 0.08511 1.1 0.987,1.23 353 3568
184.11 Malignant neoplasm of ovary neoplasms Female 0.07413 1.1 0.991,1.23 367 3659 0.08511 1.1 0.987,1.23 353 3568
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.8204 0.99 0.904,1.08 526 5253 0.881 0.993 0.907,1.09 516 5130
185 Cancer of prostate neoplasms Male 0.04365 0.953 0.909,0.999 2432 8825 0.05012 0.954 0.909,1.0 2388 8602
187 Cancer of other male genital organs neoplasms Male 0.4325 1.05 0.93,1.19 276 2723 0.6792 0.965 0.815,1.14 141 1345
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.7145 1.04 0.843,1.28 96 960 0.7063 1.04 0.843,1.29 95 933
187.2 Malignant neoplasm of testis neoplasms Male 0.7727 0.976 0.826,1.15 144 1387 0.6792 0.965 0.815,1.14 141 1345
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.5715 1.01 0.971,1.05 2552 20553 0.8054 1.01 0.927,1.1 588 5687
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.1556 1.04 0.984,1.1 1261 12588 0.2805 0.923 0.798,1.07 194 1962
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.2931 1.03 0.972,1.1 1083 10823 0.2667 1.04 0.973,1.1 1046 10563
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.2089 0.912 0.791,1.05 202 2010 0.2805 0.923 0.798,1.07 194 1962
189.2 Cancer of bladder neoplasms Both 0.4797 0.981 0.931,1.03 1575 13516 0.7328 0.99 0.937,1.05 1430 12250
189.21 Malignant neoplasm of bladder neoplasms Both 0.4955 0.981 0.929,1.04 1456 12558 0.7328 0.99 0.937,1.05 1430 12250
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.9183 1.0 0.922,1.09 601 5841 0.8054 1.01 0.927,1.1 588 5687
190 Cancer of eye neoplasms Both 0.5333 1.06 0.881,1.28 114 1125 0.2999 1.11 0.909,1.36 94 1125
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 1.698E-4 1.14 1.06,1.22 904 9040 ,
191.1 Cancer of brain and nervous system neoplasms Both 0.002239 1.14 1.05,1.24 580 5800 ,
191.11 Cancer of brain neoplasms Both 0.00302 1.15 1.05,1.26 483 4830 ,
193 Thyroid cancer neoplasms Both 0.2679 1.04 0.969,1.12 798 7953 0.3311 1.04 0.963,1.12 766 7771
194 Cancer of other endocrine glands neoplasms Both 0.1611 1.1 0.962,1.26 221 2207 0.0955 1.13 0.978,1.31 184 2159
195 Cancer, suspected or other neoplasms Both 9.772E-4 1.04 1.02,1.06 12134 23141 0.1888 1.05 0.978,1.12 896 8938
195.1 Malignant neoplasm, other neoplasms Both 8.913E-4 1.04 1.02,1.07 11693 23098 0.008511 1.03 1.01,1.06 10974 23011
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.2466 1.04 0.974,1.11 970 8963 0.1888 1.05 0.978,1.12 896 8938
196 Radiotherapy neoplasms Both 0.05129 1.05 1.0,1.1 2067 15612 0.1 1.04 0.992,1.09 1857 15554
197 Chemotherapy neoplasms Both 0.01318 1.04 1.01,1.08 4051 21210 0.09333 1.03 0.995,1.07 3710 21128
198 Secondary malignant neoplasm neoplasms Both 0.006457 1.04 1.01,1.08 4986 21474 0.5346 1.04 0.917,1.18 255 2743
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.01413 1.05 1.01,1.09 3156 19844 0.02089 1.05 1.01,1.09 2990 19770
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.00166 1.11 1.04,1.19 903 8847 0.01514 1.09 1.02,1.17 784 8815
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.195 1.05 0.975,1.13 725 7166 0.3357 1.04 0.961,1.12 675 7148
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.6012 1.02 0.943,1.11 643 6395 0.5662 1.02 0.943,1.11 587 6375
198.5 Secondary malignancy of brain/spine neoplasms Both 0.1233 1.07 0.982,1.17 545 5421 0.9397 1.0 0.894,1.13 291 5403
198.6 Secondary malignancy of bone neoplasms Both 0.5508 1.02 0.948,1.1 712 6962 0.869 1.01 0.927,1.09 603 6935
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.3733 1.06 0.937,1.19 287 2752 0.5346 1.04 0.917,1.18 255 2743
199 Neoplasm of uncertain behavior neoplasms Both 0.04169 1.03 1.0,1.07 4947 22823 0.1413 1.02 0.992,1.06 4524 22737
199.4 Neurofibromatosis neoplasms Both 0.8299 0.974 0.768,1.24 72 720 ,
200 Myeloproliferative disease neoplasms Both 0.002692 1.11 1.04,1.19 886 8851 3.236E-4 1.34 1.14,1.58 156 1584
200.1 Polycythemia vera neoplasms Both 1.738E-4 1.36 1.16,1.59 161 1610 3.236E-4 1.34 1.14,1.58 156 1584
201 Hodgkin's disease neoplasms Both 0.8375 0.982 0.826,1.17 138 1373 0.7943 0.977 0.818,1.17 132 1345
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.02951 1.06 1.01,1.13 1308 13070 0.1489 1.14 0.953,1.37 122 1270
202.2 Non-Hodgkins lymphoma neoplasms Both 0.1274 1.05 0.987,1.11 1141 11402 0.1489 1.14 0.953,1.37 122 1270
202.21 Nodular lymphoma neoplasms Both 0.5309 1.03 0.945,1.12 632 6320 0.4775 1.03 0.947,1.12 593 6184
202.22 Reticulosarcoma neoplasms Both 0.03802 1.2 1.01,1.43 137 1355 0.1374 1.15 0.958,1.37 125 1323
202.24 Large cell lymphoma neoplasms Both 0.06761 1.18 0.988,1.41 132 1300 0.1489 1.14 0.953,1.37 122 1270
204 Leukemia neoplasms Both 0.3055 1.05 0.959,1.14 545 5450 0.492 1.06 0.902,1.24 171 1749
204.1 Lymphoid leukemia neoplasms Both 0.15 1.11 0.961,1.29 187 1870 0.507 1.06 0.89,1.27 128 1321
204.11 Lymphoid leukemia, acute neoplasms Both 0.07586 1.26 0.976,1.63 58 580 0.1161 1.23 0.949,1.61 55 565
204.12 Lymphoid leukemia, chronic neoplasms Both 0.2944 1.1 0.924,1.3 136 1350 0.507 1.06 0.89,1.27 128 1321
204.2 Myeloid leukemia neoplasms Both 0.6295 1.04 0.899,1.19 206 2060 0.2547 1.12 0.923,1.36 116 1208
204.21 Myeloid leukemia, acute neoplasms Both 0.4498 1.07 0.892,1.29 124 1240 0.2547 1.12 0.923,1.36 116 1208
204.4 Multiple myeloma neoplasms Both 0.3926 1.07 0.916,1.25 180 1795 0.492 1.06 0.902,1.24 171 1749
208 Benign neoplasm of colon neoplasms Both 0.3698 0.989 0.964,1.01 8098 29324 0.561 0.993 0.968,1.02 7941 28600
209 Neuroendocrine tumors neoplasms Both 0.1038 1.12 0.978,1.27 222 2220 0.1905 1.09 0.956,1.25 213 2167
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.7745 0.993 0.943,1.05 1584 15798 0.8472 0.995 0.944,1.05 1544 15424
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.7925 0.996 0.969,1.02 5807 30296 0.8091 0.997 0.969,1.03 5692 29585
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.9099 1.0 0.952,1.06 1556 15533 0.6501 1.01 0.96,1.07 1484 15177
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.5636 1.02 0.962,1.07 1405 13304 0.7096 1.01 0.955,1.07 1310 13141
214 Lipoma neoplasms Both 0.984 1.0 0.941,1.06 1117 11124 0.5224 0.974 0.9,1.06 662 6646
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.4943 0.973 0.899,1.05 681 6793 0.5224 0.974 0.9,1.06 662 6646
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.5495 1.01 0.976,1.05 3594 32904 0.4932 1.01 0.977,1.05 3465 32167
216 Benign neoplasm of skin neoplasms Both 0.005754 1.03 1.01,1.06 9073 29036 0.6501 1.05 0.859,1.28 109 1069
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.6053 1.05 0.865,1.28 111 1093 0.6501 1.05 0.859,1.28 109 1069
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.04074 1.07 1.0,1.13 1150 11417 0.02399 1.08 1.01,1.15 1043 10356
217.1 Nevus, non-neoplastic neoplasms Both 0.02399 1.08 1.01,1.15 1063 10579 0.02399 1.08 1.01,1.15 1043 10356
218 Benign neoplasm of uterus neoplasms Female 0.1213 1.03 0.992,1.07 3552 13845 0.7516 1.01 0.966,1.05 2781 13363
218.1 Uterine leiomyoma neoplasms Female 0.002138 1.09 1.03,1.15 1506 13465 0.003631 1.08 1.03,1.14 1479 13135
218.2 Other benign neoplasm of uterus neoplasms Female 0.6918 1.01 0.968,1.05 2824 13698 0.7516 1.01 0.966,1.05 2781 13363
220 Benign neoplasm of ovary neoplasms Female 0.8375 0.992 0.921,1.07 763 7571 0.9931 1.0 0.927,1.08 754 7389
221 Benign neoplasm of other female genital organs neoplasms Female 0.52 1.02 0.966,1.07 1666 12074 0.4217 1.02 0.97,1.08 1643 11796
222 Benign neoplasm of male genital organs neoplasms Male 0.2553 0.962 0.9,1.03 954 9116 0.3304 0.967 0.904,1.03 940 8873
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.6124 1.01 0.961,1.07 1547 11080 0.4477 1.02 0.967,1.08 1529 10948
224 Benign neoplasm of eye neoplasms Both 0.3499 1.04 0.954,1.14 511 5062 0.4831 1.04 0.937,1.15 415 4230
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.3055 1.05 0.954,1.16 429 4230 0.4831 1.04 0.937,1.15 415 4230
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.05623 1.06 0.998,1.13 1039 10379 0.7211 0.972 0.832,1.14 158 2420
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.02512 1.08 1.01,1.16 817 8160 0.1119 1.08 0.982,1.18 442 8160
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.811 1.02 0.894,1.15 242 2420 0.7211 0.972 0.832,1.14 158 2420
226 Benign neoplasm of thyroid glands neoplasms Both 0.0871 1.06 0.992,1.12 1082 10810 0.05248 1.06 0.999,1.13 1059 10568
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.0955 1.05 0.992,1.11 1387 13870 0.2455 1.07 0.955,1.2 321 3637
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.1312 1.08 0.976,1.2 375 3745 0.1208 1.09 0.978,1.21 359 3662
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.9705 1.0 0.924,1.09 644 6434 0.879 1.01 0.928,1.09 641 6285
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.3076 1.06 0.951,1.17 373 3724 0.2455 1.07 0.955,1.2 321 3637
228 Hemangioma and lymphangioma, any site neoplasms Both 0.02042 1.06 1.01,1.12 1517 15150 0.0871 1.06 0.991,1.14 818 8296
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.03981 1.08 1.0,1.15 849 8478 0.0871 1.06 0.991,1.14 818 8296
229 Benign neoplasm of unspecified sites neoplasms Both 0.6124 1.01 0.98,1.03 6631 31223 0.5176 1.01 0.98,1.04 4797 29034
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.526 1.01 0.98,1.04 4904 29712 0.5176 1.01 0.98,1.04 4797 29034
860 Bone marrow or stem cell transplant neoplasms Both 0.1726 1.14 0.945,1.37 127 1266 0.3698 1.09 0.902,1.32 122 1243
240 Simple and unspecified goiter endocrine/metabolic Both 0.3882 1.03 0.959,1.11 767 7647 0.4498 1.03 0.955,1.11 749 7501
241 Nontoxic nodular goiter endocrine/metabolic Both 0.2489 1.03 0.982,1.07 2274 18240 0.08318 1.06 0.992,1.13 993 9855
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.04467 1.05 1.0,1.1 1795 16440 0.03162 1.06 1.0,1.11 1743 16097
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.1439 1.05 0.984,1.12 1017 10065 0.08318 1.06 0.992,1.13 993 9855
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.006166 1.09 1.02,1.16 1075 10635 0.7178 1.03 0.86,1.25 114 1134
242.1 Graves' disease endocrine/metabolic Both 0.1028 1.09 0.983,1.2 399 3965 0.1799 1.07 0.968,1.19 390 3862
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.2123 1.14 0.93,1.39 98 978 0.1879 1.14 0.936,1.4 96 957
242.3 Exophthalmos endocrine/metabolic Both 0.3483 1.06 0.934,1.21 245 2447 0.7178 1.03 0.86,1.25 114 1134
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.5861 1.05 0.876,1.26 116 1160 0.7178 1.03 0.86,1.25 114 1134
244 Hypothyroidism endocrine/metabolic Both 0.3048 1.01 0.987,1.04 6448 27183 0.2844 1.02 0.987,1.05 5827 26142
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.01122 1.07 1.02,1.13 1421 14153 0.0123 1.07 1.02,1.13 1366 13864
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.1403 1.05 0.983,1.13 853 8502 0.1352 1.06 0.983,1.14 807 8311
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.4093 1.01 0.983,1.04 5996 26719 0.2844 1.02 0.987,1.05 5827 26142
245 Thyroiditis endocrine/metabolic Both 0.4966 0.97 0.89,1.06 574 5720 0.2818 0.948 0.86,1.04 450 4428
245.2 Chronic thyroiditis endocrine/metabolic Both 0.2871 0.949 0.862,1.04 463 4617 0.2818 0.948 0.86,1.04 450 4428
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.2649 0.946 0.859,1.04 456 4533 0.2818 0.948 0.86,1.04 450 4428
246 Other disorders of thyroid endocrine/metabolic Both 0.3105 1.02 0.985,1.05 5018 25158 0.4977 1.03 0.945,1.12 544 5541
246.2 Thyroid cyst endocrine/metabolic Both 0.151 0.844 0.67,1.06 83 804 0.05248 0.791 0.624,1.0 81 786
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.4819 1.03 0.947,1.12 568 5651 0.4977 1.03 0.945,1.12 544 5541
249 Secondary diabetes mellitus endocrine/metabolic Both 0.9886 0.999 0.924,1.08 686 6849 0.7447 0.987 0.91,1.07 655 6710
250 Diabetes mellitus endocrine/metabolic Both 0.2564 0.987 0.964,1.01 10115 27568 0.3639 0.967 0.899,1.04 800 7967
250.1 Type 1 diabetes endocrine/metabolic Both 0.7907 1.01 0.947,1.07 1053 10521 0.5943 1.07 0.841,1.35 68 669
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.6237 1.06 0.849,1.32 80 792 0.6295 1.06 0.847,1.32 79 774
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.7345 1.02 0.897,1.17 235 2346 0.7816 1.02 0.892,1.16 230 2294
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.778 1.02 0.901,1.15 280 2800 0.8072 1.02 0.898,1.15 274 2726
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.3006 1.07 0.94,1.22 238 2372 0.3342 1.07 0.935,1.22 232 2314
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.6353 1.06 0.837,1.34 70 690 0.5943 1.07 0.841,1.35 68 669
250.2 Type 2 diabetes endocrine/metabolic Both 0.08128 0.976 0.95,1.0 7035 26169 0.912 0.995 0.908,1.09 507 4971
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.02951 1.23 1.02,1.47 120 1200 0.03162 1.22 1.02,1.47 119 1167
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.2056 0.961 0.904,1.02 1133 11056 0.236 0.963 0.905,1.02 1118 10809
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.5236 0.977 0.91,1.05 826 8208 0.4436 0.972 0.905,1.04 809 8015
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.4102 0.977 0.926,1.03 1419 13969 0.3475 0.974 0.922,1.03 1387 13647
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.9441 0.997 0.91,1.09 513 5077 0.912 0.995 0.908,1.09 507 4971
250.3 Insulin pump user endocrine/metabolic Both 0.6471 0.989 0.943,1.04 1884 17814 0.5321 0.985 0.939,1.03 1835 17420
250.4 Abnormal glucose endocrine/metabolic Both 0.861 1.0 0.973,1.03 5404 26451 0.9141 0.998 0.967,1.03 4547 25318
250.41 Impaired fasting glucose endocrine/metabolic Both 0.8511 0.995 0.94,1.05 1326 13130 0.8511 0.995 0.939,1.05 1297 12828
250.42 Other abnormal glucose endocrine/metabolic Both 0.8204 1.0 0.973,1.04 4736 25883 0.9141 0.998 0.967,1.03 4547 25318
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.4519 1.09 0.868,1.37 78 747 0.6699 1.05 0.834,1.33 77 732
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.7798 1.01 0.949,1.07 1137 11335 0.867 1.01 0.945,1.07 1109 11069
250.7 Diabetic retinopathy endocrine/metabolic Both 0.3846 0.969 0.902,1.04 821 8168 0.3639 0.967 0.899,1.04 800 7967
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.7551 0.987 0.908,1.07 595 5901 0.4764 0.972 0.899,1.05 676 6876
251.1 Hypoglycemia endocrine/metabolic Both 0.6823 0.984 0.911,1.06 702 7015 0.4764 0.972 0.899,1.05 676 6876
252 Disorders of parathyroid gland endocrine/metabolic Both 0.5058 1.02 0.968,1.07 1807 17879 0.02884 1.12 1.01,1.24 387 3842
252.1 Hyperparathyroidism endocrine/metabolic Both 0.875 1.0 0.954,1.06 1656 16459 0.6683 1.01 0.961,1.06 1627 16124
252.2 Hypoparathyroidism endocrine/metabolic Both 0.03715 1.11 1.01,1.23 393 3922 0.02884 1.12 1.01,1.24 387 3842
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.01778 1.1 1.02,1.19 691 6893 0.9016 0.985 0.783,1.24 85 905
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.3404 1.07 0.931,1.23 205 2041 0.03548 1.3 1.02,1.66 66 701
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.0263 1.31 1.03,1.65 72 720 0.03548 1.3 1.02,1.66 66 701
253.2 Pituitary hypofunction endocrine/metabolic Both 0.6699 0.967 0.831,1.13 184 1840 0.4395 0.933 0.782,1.11 135 1789
253.3 Diabetes insipidus endocrine/metabolic Both 0.2014 1.17 0.919,1.49 70 694 0.1928 1.19 0.915,1.55 59 672
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.03162 1.27 1.02,1.58 92 899 0.02951 1.29 1.03,1.63 83 872
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.7278 1.04 0.835,1.29 93 925 0.9016 0.985 0.783,1.24 85 905
255 Disorders of adrenal glands endocrine/metabolic Both 4.898E-4 1.11 1.05,1.18 1186 11860 0.9572 0.997 0.899,1.11 404 4403
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.4819 1.04 0.926,1.18 290 2886 0.2999 1.11 0.911,1.36 103 1038
255.11 Cushing's syndrome endocrine/metabolic Both 0.5117 1.06 0.89,1.26 144 1440 0.4539 1.07 0.893,1.29 130 1407
255.12 Hyperaldosteronism endocrine/metabolic Both 0.2618 1.12 0.92,1.36 106 1057 0.2999 1.11 0.911,1.36 103 1038
255.2 Adrenal hypofunction endocrine/metabolic Both 0.547 1.03 0.936,1.13 477 4758 0.9572 0.997 0.899,1.11 404 4403
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.7178 1.02 0.923,1.12 451 4496 0.9572 0.997 0.899,1.11 404 4403
256 Ovarian dysfunction endocrine/metabolic Female 0.5875 0.981 0.914,1.05 859 8184 0.7534 0.986 0.902,1.08 536 5332
256.4 Polycystic ovaries endocrine/metabolic Female 0.7674 0.987 0.903,1.08 544 5436 0.7534 0.986 0.902,1.08 536 5332
257 Testicular dysfunction endocrine/metabolic Male 0.6653 1.02 0.943,1.1 747 7455 0.863 1.01 0.931,1.09 696 7057
257.1 Testicular hypofunction endocrine/metabolic Male 0.8995 1.0 0.93,1.09 725 7234 0.863 1.01 0.931,1.09 696 7057
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.4732 1.09 0.86,1.38 66 660 0.6012 1.06 0.853,1.32 92 901
258.1 Postablative ovarian failure endocrine/metabolic Female 0.5875 1.06 0.854,1.32 92 920 0.6012 1.06 0.853,1.32 92 901
259 Other endocrine disorders endocrine/metabolic Both 0.5321 1.02 0.95,1.1 759 7562 0.3733 1.04 0.959,1.12 733 7409
260 Protein-calorie malnutrition endocrine/metabolic Both 0.9616 0.999 0.958,1.04 2353 22279 0.9078 1.0 0.926,1.09 630 6588
260.1 Cachexia endocrine/metabolic Both 0.8511 0.988 0.867,1.12 239 2388 0.6561 0.97 0.848,1.11 225 2338
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.7396 0.991 0.937,1.05 1363 13589 0.1138 0.919 0.828,1.02 392 4048
260.22 Nutritional marasmus endocrine/metabolic Both 0.278 0.945 0.854,1.05 413 4130 0.1138 0.919 0.828,1.02 392 4048
260.3 Adult failure to thrive endocrine/metabolic Both 0.6368 1.02 0.934,1.12 509 5051 0.6209 1.02 0.933,1.12 473 4944
260.6 Anorexia endocrine/metabolic Both 0.4426 1.03 0.953,1.12 677 6722 0.9078 1.0 0.926,1.09 630 6588
261 Vitamin deficiency endocrine/metabolic Both 0.2183 0.982 0.954,1.01 5614 30157 0.4266 0.988 0.959,1.02 5148 29234
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.7816 1.01 0.933,1.1 649 6482 0.9594 1.0 0.923,1.09 628 6344
261.4 Vitamin D deficiency endocrine/metabolic Both 0.3327 0.985 0.957,1.02 5264 29859 0.4266 0.988 0.959,1.02 5148 29234
262 Mineral deficiency NEC endocrine/metabolic Both 0.7709 1.01 0.942,1.08 854 8532 0.5212 1.02 0.953,1.1 839 8340
263 Other nutritional deficiency endocrine/metabolic Both 0.5212 1.03 0.934,1.14 412 4113 0.4742 1.04 0.937,1.15 392 4032
264 Lack of normal physiological development endocrine/metabolic Both 0.317 0.923 0.789,1.08 175 1735 0.8017 1.04 0.79,1.36 59 595
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.8375 0.979 0.804,1.19 95 950 0.7211 0.963 0.784,1.18 88 925
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.7211 1.05 0.804,1.37 61 607 0.8017 1.04 0.79,1.36 59 595
269 Proteinuria endocrine/metabolic Both 0.6653 0.986 0.927,1.05 1079 10768 0.6209 0.984 0.924,1.05 1049 10486
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.6714 1.02 0.943,1.1 740 7378 0.3273 1.07 0.932,1.23 209 2125
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.7798 0.974 0.809,1.17 129 1283 0.873 0.983 0.801,1.21 101 973
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.871 0.983 0.8,1.21 101 998 0.873 0.983 0.801,1.21 101 973
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.3396 0.897 0.718,1.12 81 810 0.2911 0.883 0.702,1.11 77 793
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.3388 1.04 0.957,1.14 560 5581 0.3273 1.07 0.932,1.23 209 2125
270.32 Paraproteinemia endocrine/metabolic Both 0.7063 1.02 0.91,1.15 301 2982 0.787 1.02 0.902,1.15 290 2912
270.33 Amyloidosis endocrine/metabolic Both 0.375 0.88 0.664,1.17 55 550 ,
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.2042 1.09 0.953,1.25 218 2178 0.3273 1.07 0.932,1.23 209 2125
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.0309 1.05 1.0,1.1 1952 19491 0.6095 1.06 0.846,1.33 79 790
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.03388 1.05 1.0,1.1 1885 18823 0.02951 1.05 1.01,1.11 1856 18366
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.5188 1.08 0.861,1.34 81 810 0.6095 1.06 0.846,1.33 79 790
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.05754 0.978 0.957,1.0 14793 22696 0.6166 0.966 0.846,1.1 235 2365
272.1 Hyperlipidemia endocrine/metabolic Both 0.05129 0.978 0.956,1.0 14763 22682 0.871 0.996 0.953,1.04 2224 15096
272.11 Hypercholesterolemia endocrine/metabolic Both 0.1782 0.977 0.945,1.01 4668 18640 0.177 0.977 0.944,1.01 4563 18170
272.12 Hyperglyceridemia endocrine/metabolic Both 0.5559 0.98 0.916,1.05 945 9395 0.6577 0.985 0.92,1.05 924 9130
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.9078 0.997 0.954,1.04 2272 15492 0.871 0.996 0.953,1.04 2224 15096
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.6412 0.969 0.85,1.1 244 2425 0.6166 0.966 0.846,1.1 235 2365
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.3917 0.98 0.935,1.03 1971 18337 0.4624 0.937 0.787,1.12 139 1329
274.1 Gout endocrine/metabolic Both 0.5105 0.984 0.938,1.03 1879 17712 0.4634 0.973 0.904,1.05 779 7676
274.11 Gouty arthropathy endocrine/metabolic Both 0.4395 0.972 0.903,1.05 793 7891 0.4634 0.973 0.904,1.05 779 7676
274.2 Crystal arthropathies endocrine/metabolic Both 0.309 0.915 0.771,1.09 146 1425 0.4624 0.937 0.787,1.12 139 1329
274.21 Chondrocalcinosis endocrine/metabolic Both 0.3926 0.927 0.778,1.1 140 1363 0.4624 0.937 0.787,1.12 139 1329
275 Disorders of mineral metabolism endocrine/metabolic Both 0.8054 0.995 0.96,1.03 3252 30253 0.7244 0.958 0.754,1.22 68 682
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.08128 1.07 0.992,1.14 845 8441 0.07244 1.07 0.994,1.15 820 8232
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.6998 0.992 0.952,1.03 2502 24757 0.869 1.01 0.942,1.07 994 9952
275.51 Hypocalcemia endocrine/metabolic Both 0.7261 0.986 0.913,1.07 722 7203 0.787 0.989 0.915,1.07 703 7019
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.9354 1.0 0.94,1.07 1024 10193 0.869 1.01 0.942,1.07 994 9952
275.6 Hypercalcemia endocrine/metabolic Both 0.9441 1.0 0.94,1.07 1043 10415 0.7568 1.01 0.947,1.08 1016 10180
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.4539 1.01 0.984,1.04 7227 30901 0.6383 0.951 0.771,1.17 96 974
276.1 Electrolyte imbalance endocrine/metabolic Both 0.4688 1.01 0.981,1.04 4833 28673 0.5483 1.02 0.965,1.07 1574 15840
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.7727 1.01 0.918,1.12 415 4115 0.6516 1.02 0.924,1.14 391 4052
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.8299 0.995 0.949,1.04 1857 17982 0.6281 0.988 0.941,1.04 1734 17650
276.13 Hyperpotassemia endocrine/metabolic Both 0.1416 1.03 0.989,1.08 2238 20576 0.1236 1.04 0.991,1.08 2183 20183
276.14 Hypopotassemia endocrine/metabolic Both 0.5534 1.02 0.965,1.07 1626 16160 0.5483 1.02 0.965,1.07 1574 15840
276.4 Acid-base balance disorder endocrine/metabolic Both 0.9354 1.0 0.952,1.05 1593 15855 0.7603 0.983 0.879,1.1 339 3438
276.41 Acidosis endocrine/metabolic Both 0.7413 1.01 0.955,1.07 1357 13508 0.863 1.0 0.95,1.06 1313 13251
276.42 Alkalosis endocrine/metabolic Both 0.811 0.987 0.884,1.1 350 3498 0.7603 0.983 0.879,1.1 339 3438
276.5 Hypovolemia endocrine/metabolic Both 0.5433 1.01 0.976,1.05 3615 28901 0.5702 1.01 0.975,1.05 3430 28353
276.6 Fluid overload endocrine/metabolic Both 0.3581 1.03 0.967,1.1 1046 10404 0.3707 1.03 0.966,1.1 1019 10199
276.8 Polydipsia endocrine/metabolic Both 0.5395 0.937 0.763,1.15 99 990 0.6383 0.951 0.771,1.17 96 974
277 Other disorders of metabolism endocrine/metabolic Both 0.8954 1.0 0.952,1.06 1534 15324 0.6124 1.02 0.94,1.11 601 5951
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.3972 0.945 0.83,1.08 252 2520 0.4786 0.954 0.837,1.09 247 2466
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.2673 1.05 0.963,1.15 547 5456 0.2838 1.05 0.961,1.15 535 5338
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.4207 0.968 0.894,1.05 675 6743 0.9638 0.998 0.915,1.09 559 5524
277.51 Lipoprotein disorders endocrine/metabolic Both 0.7534 0.986 0.905,1.07 567 5665 0.9638 0.998 0.915,1.09 559 5524
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.5728 1.02 0.943,1.11 610 6090 0.6124 1.02 0.94,1.11 601 5951
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.2793 0.989 0.969,1.01 15130 23191 0.4808 0.981 0.929,1.04 1484 13393
278.1 Obesity endocrine/metabolic Both 0.3793 0.99 0.97,1.01 13507 23193 0.4571 0.989 0.962,1.02 6219 22649
278.11 Morbid obesity endocrine/metabolic Both 0.4786 0.99 0.963,1.02 6376 23143 0.4571 0.989 0.962,1.02 6219 22649
278.3 Localized adiposity endocrine/metabolic Both 0.2661 0.933 0.825,1.05 270 2694 0.2704 0.933 0.825,1.06 268 2633
278.4 Abnormal weight gain endocrine/metabolic Both 0.3508 0.975 0.924,1.03 1522 13685 0.4808 0.981 0.929,1.04 1484 13393
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.414 1.02 0.975,1.06 2245 22393 0.5754 1.03 0.931,1.14 433 4334
279.1 Immunity deficiency endocrine/metabolic Both 0.526 1.02 0.954,1.1 881 8792 0.008318 1.19 1.05,1.36 249 2486
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.00537 1.2 1.06,1.37 254 2540 0.008318 1.19 1.05,1.36 249 2486
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.8433 0.991 0.909,1.08 574 5735 0.9484 0.997 0.914,1.09 566 5603
279.7 Other immunological findings endocrine/metabolic Both 0.6902 1.01 0.974,1.04 3927 30734 0.4416 1.01 0.98,1.05 3823 30014
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.6412 1.02 0.928,1.13 443 4423 0.5754 1.03 0.931,1.14 433 4334
275.1 Disorders of iron metabolism hematopoietic Both 0.8299 0.983 0.841,1.15 168 1680 0.7244 0.958 0.754,1.22 68 682
275.11 Hereditary hemochromatosis hematopoietic Both 0.6237 0.942 0.743,1.19 70 700 0.7244 0.958 0.754,1.22 68 682
280 Iron deficiency anemias hematopoietic Both 0.8954 0.998 0.963,1.03 3537 25593 0.7745 0.992 0.937,1.05 1326 13218
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.6855 0.993 0.957,1.03 3410 25349 0.6486 0.992 0.956,1.03 3323 24827
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.984 0.999 0.945,1.06 1361 13511 0.7745 0.992 0.937,1.05 1326 13218
281 Other deficiency anemia hematopoietic Both 0.1807 1.07 0.967,1.19 387 3838 0.5346 1.05 0.906,1.21 204 2045
281.1 Megaloblastic anemia hematopoietic Both 0.4236 1.06 0.916,1.23 189 1875 0.309 1.1 0.918,1.31 133 1318
281.11 Pernicious anemia hematopoietic Both 0.271 1.13 0.908,1.41 84 830 0.2218 1.15 0.92,1.43 83 811
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.3311 1.09 0.915,1.3 135 1348 0.309 1.1 0.918,1.31 133 1318
281.9 Deficiency anemias hematopoietic Both 0.6194 1.04 0.9,1.19 214 2110 0.5346 1.05 0.906,1.21 204 2045
282 Hereditary hemolytic anemias hematopoietic Both 0.6546 1.03 0.906,1.17 248 2443 0.5984 0.956 0.807,1.13 139 1394
282.8 Other hemoglobinopathies hematopoietic Both 0.879 1.01 0.861,1.19 158 1541 0.9817 0.998 0.847,1.18 155 1516
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.881 0.987 0.836,1.17 143 1420 0.5984 0.956 0.807,1.13 139 1394
283 Acquired hemolytic anemias hematopoietic Both 0.1782 1.13 0.945,1.36 130 1295 0.3148 1.1 0.914,1.32 124 1261
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.006918 1.47 1.11,1.95 54 532 ,
284 Aplastic anemia hematopoietic Both 0.4295 0.965 0.884,1.05 558 5545 0.1607 0.933 0.848,1.03 460 4744
284.1 Pancytopenia hematopoietic Both 0.3083 0.952 0.867,1.05 488 4847 0.1607 0.933 0.848,1.03 460 4744
285 Other anemias hematopoietic Both 0.865 0.998 0.975,1.02 9426 28014 0.06761 1.09 0.994,1.19 508 5426
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.0138 0.949 0.911,0.99 2536 22457 0.00912 0.945 0.906,0.986 2442 21979
285.2 Anemia of chronic disease hematopoietic Both 0.1702 1.04 0.985,1.09 1584 15823 0.06761 1.09 0.994,1.19 508 5426
285.21 Anemia in chronic kidney disease hematopoietic Both 0.4198 0.968 0.894,1.05 673 6722 0.4227 0.968 0.893,1.05 660 6580
285.22 Anemia in neoplastic disease hematopoietic Both 0.01479 1.11 1.02,1.22 555 5536 0.06761 1.09 0.994,1.19 508 5426
286 Coagulation defects hematopoietic Both 0.7194 0.993 0.956,1.03 3013 27144 0.4932 1.02 0.956,1.1 858 8579
286.1 Congenital coagulation defects hematopoietic Both 0.3006 0.923 0.794,1.07 190 1889 0.9016 0.986 0.791,1.23 93 948
286.11 Von willebrand's disease hematopoietic Both 0.3236 0.882 0.687,1.13 64 640 0.2871 0.872 0.677,1.12 62 631
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.8299 0.977 0.787,1.21 98 973 0.9016 0.986 0.791,1.23 93 948
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.879 0.997 0.957,1.04 2601 20964 0.8851 0.997 0.956,1.04 2513 20508
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.871 0.978 0.749,1.28 60 590 0.881 0.98 0.751,1.28 60 583
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.6966 0.971 0.838,1.13 186 1860 0.8337 0.984 0.848,1.14 181 1824
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.826 0.977 0.796,1.2 92 906 0.9354 0.991 0.807,1.22 91 886
286.6 Defibrination syndrome hematopoietic Both 0.2317 0.972 0.928,1.02 1964 19522 0.1694 0.967 0.923,1.01 1894 19098
286.7 Other and unspecified coagulation defects hematopoietic Both 0.3606 0.98 0.939,1.02 2349 23153 0.2838 0.977 0.935,1.02 2271 22661
286.8 Hypercoagulable state hematopoietic Both 0.2382 1.05 0.968,1.14 643 6420 0.5358 1.03 0.944,1.12 600 6039
286.81 Primary hypercoagulable state hematopoietic Both 0.5395 1.03 0.945,1.11 618 6179 0.5358 1.03 0.944,1.12 600 6039
286.9 Abnormal coagulation profile hematopoietic Both 0.3281 1.03 0.967,1.11 890 8770 0.4932 1.02 0.956,1.1 858 8579
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.2564 1.02 0.983,1.07 2575 22699 0.3436 1.12 0.89,1.4 73 745
287.1 Spontaneous ecchymoses hematopoietic Both 0.3243 1.09 0.921,1.28 154 1532 0.3664 1.08 0.914,1.28 153 1493
287.3 Thrombocytopenia hematopoietic Both 0.6397 1.01 0.968,1.05 2297 20909 0.2735 1.06 0.955,1.18 381 4257
287.31 Primary thrombocytopenia hematopoietic Both 0.3304 1.05 0.954,1.15 481 4785 0.4581 1.04 0.943,1.14 461 4693
287.32 Secondary thrombocytopenia hematopoietic Both 0.07244 1.09 0.992,1.21 436 4360 0.2735 1.06 0.955,1.18 381 4257
287.4 Qualitative platelet defects hematopoietic Both 0.2897 1.13 0.903,1.41 76 760 0.3436 1.12 0.89,1.4 73 745
288 Diseases of white blood cells hematopoietic Both 0.3251 1.02 0.983,1.05 3850 30383 0.1718 1.14 0.945,1.37 119 1250
288.1 Decreased white blood cell count hematopoietic Both 0.1035 1.05 0.99,1.11 1252 12520 0.05495 1.07 0.999,1.15 832 8766
288.11 Neutropenia hematopoietic Both 0.007762 1.1 1.02,1.17 896 8960 0.05495 1.07 0.999,1.15 832 8766
288.2 Elevated white blood cell count hematopoietic Both 0.8375 1.0 0.968,1.04 3179 28632 0.859 0.997 0.96,1.03 3041 28065
288.3 Eosinophilia hematopoietic Both 0.05248 1.19 0.998,1.43 128 1278 0.1718 1.14 0.945,1.37 119 1250
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.1517 1.04 0.985,1.11 1259 12554 0.8933 1.01 0.89,1.14 276 2717
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.1641 1.06 0.976,1.15 615 6123 0.2089 1.05 0.971,1.15 601 6010
289.4 Lymphadenitis hematopoietic Both 0.2339 1.02 0.986,1.06 3186 28420 0.241 1.02 0.985,1.06 3053 27868
289.5 Diseases of spleen hematopoietic Both 0.7962 0.985 0.877,1.11 313 3130 0.6714 0.974 0.865,1.1 297 3076
289.8 Polycythemia, secondary hematopoietic Both 0.004467 1.24 1.07,1.45 182 1820 0.008128 1.23 1.05,1.43 178 1790
289.9 Abnormality of red blood cells hematopoietic Both 0.8318 1.01 0.896,1.15 281 2776 0.8933 1.01 0.89,1.14 276 2717
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.7603 1.01 0.947,1.08 1040 9399 0.7727 0.987 0.906,1.08 577 6267
290.1 Dementias mental disorders Both 0.867 1.01 0.911,1.12 407 3816 0.8913 1.02 0.767,1.36 51 502
290.11 Alzheimer's disease mental disorders Both 0.929 1.01 0.827,1.23 104 984 0.955 1.01 0.822,1.23 99 968
290.12 Dementia with cerebral degenerations mental disorders Both 0.8072 0.97 0.763,1.23 71 705 0.7852 0.966 0.755,1.24 68 697
290.13 Senile dementia mental disorders Both 0.05248 1.14 0.999,1.29 257 2376 0.05248 1.14 0.998,1.3 246 2340
290.16 Vascular dementia mental disorders Both 0.875 1.02 0.772,1.35 53 508 0.8913 1.02 0.767,1.36 51 502
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.6699 1.02 0.938,1.1 634 6242 0.5623 1.03 0.943,1.12 592 6146
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.7047 1.02 0.937,1.1 642 6369 0.7727 0.987 0.906,1.08 577 6267
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.5383 1.01 0.969,1.06 1977 19673 0.6839 1.01 0.959,1.07 1472 15238
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.5521 1.05 0.894,1.23 161 1610 0.6124 1.04 0.887,1.23 158 1586
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.5741 1.03 0.927,1.15 364 3634 0.9886 1.0 0.893,1.12 322 3580
291.8 Alteration of consciousness mental disorders Both 0.6095 1.01 0.962,1.07 1563 15497 0.6839 1.01 0.959,1.07 1472 15238
292 Neurological disorders mental disorders Both 0.9954 1.0 0.969,1.03 4340 31695 0.2198 1.11 0.938,1.32 138 1414
292.1 Aphasia/speech disturbance mental disorders Both 0.2317 1.03 0.98,1.09 1554 15459 0.2606 1.11 0.928,1.32 132 1597
292.11 Aphasia mental disorders Both 0.002089 1.15 1.05,1.26 516 5142 0.1845 1.07 0.967,1.19 363 5057
292.12 Symbolic dysfunction mental disorders Both 0.05495 1.17 0.996,1.37 162 1620 0.2606 1.11 0.928,1.32 132 1597
292.2 Mild cognitive impairment mental disorders Both 0.9204 1.01 0.89,1.14 276 2716 0.798 0.983 0.865,1.12 251 2670
292.3 Memory loss mental disorders Both 0.03715 0.943 0.892,0.996 1405 13752 0.01778 0.933 0.88,0.988 1292 13538
292.4 Altered mental status mental disorders Both 0.9954 1.0 0.954,1.05 1885 18096 0.7261 0.991 0.943,1.04 1710 17814
292.5 Transient alteration of awareness mental disorders Both 0.8551 0.99 0.883,1.11 327 3237 0.6934 0.976 0.865,1.1 288 3175
292.6 Hallucinations mental disorders Both 0.1309 1.14 0.962,1.35 144 1429 0.2198 1.11 0.938,1.32 138 1414
293 Symptoms involving head and neck mental disorders Both 0.7621 1.02 0.904,1.15 304 3036 0.6792 1.01 0.972,1.04 3279 31962
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.2 1.02 0.988,1.06 3691 32427 0.6792 1.01 0.972,1.04 3279 31962
295 Schizophrenia and other psychotic disorders mental disorders Both 0.5741 1.02 0.945,1.11 664 6564 0.6855 1.02 0.929,1.12 486 5110
295.1 Schizophrenia mental disorders Both 0.869 1.02 0.836,1.24 111 1080 0.955 1.01 0.825,1.23 109 1062
295.2 Paranoid disorders mental disorders Both 0.7656 1.03 0.829,1.29 86 856 0.6412 1.06 0.839,1.33 80 841
295.3 Psychosis mental disorders Both 0.6166 1.02 0.935,1.12 527 5206 0.6855 1.02 0.929,1.12 486 5110
296 Mood disorders mental disorders Both 0.3926 0.99 0.967,1.01 12028 17942 0.5236 0.992 0.968,1.02 10487 17601
296.1 Bipolar mental disorders Both 0.3006 0.966 0.905,1.03 994 9331 0.3707 0.97 0.908,1.04 973 9151
296.2 Depression mental disorders Both 0.5012 0.992 0.969,1.02 11641 17941 0.5236 0.992 0.968,1.02 10487 17601
296.22 Major depressive disorder mental disorders Both 0.5598 0.993 0.969,1.02 10773 17942 0.5236 0.992 0.968,1.02 10487 17601
297 Suicidal ideation or attempt mental disorders Both 0.877 1.01 0.931,1.09 696 6932 0.8974 1.01 0.875,1.16 200 1974
297.1 Suicidal ideation mental disorders Both 0.7907 1.01 0.928,1.1 559 5575 0.7345 1.02 0.93,1.11 542 5477
297.2 Suicide or self-inflicted injury mental disorders Both 0.869 1.01 0.878,1.17 201 2010 0.8974 1.01 0.875,1.16 200 1974
300 Anxiety disorders mental disorders Both 0.6368 1.01 0.982,1.03 12038 17949 0.6653 1.02 0.937,1.11 601 5989
300.1 Anxiety disorder mental disorders Both 0.7621 1.0 0.98,1.03 11352 17942 0.826 0.991 0.917,1.07 678 7091
300.11 Generalized anxiety disorder mental disorders Both 0.5012 1.01 0.978,1.05 4496 17788 0.5012 1.01 0.978,1.05 4372 17449
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.2523 0.962 0.899,1.03 957 9152 0.2851 0.964 0.9,1.03 931 8970
300.13 Phobia mental disorders Both 0.9954 1.0 0.927,1.08 731 7231 0.826 0.991 0.917,1.07 678 7091
300.3 Obsessive-compulsive disorders mental disorders Both 0.8299 1.01 0.886,1.16 223 2230 0.6577 1.03 0.9,1.18 219 2179
300.4 Dysthymic disorder mental disorders Both 0.2972 0.974 0.927,1.02 1798 13630 0.2951 0.974 0.926,1.02 1743 13368
300.8 Acute reaction to stress mental disorders Both 0.8892 0.992 0.892,1.1 359 3536 0.5559 0.968 0.868,1.08 350 3474
300.9 Posttraumatic stress disorder mental disorders Both 0.6902 1.02 0.936,1.11 612 6113 0.6653 1.02 0.937,1.11 601 5989
301 Personality disorders mental disorders Both 0.5808 0.97 0.869,1.08 363 3626 0.5433 0.954 0.819,1.11 183 1836
301.2 Antisocial/borderline personality disorder mental disorders Both 0.455 0.944 0.812,1.1 187 1868 0.5433 0.954 0.819,1.11 183 1836
302 Sexual and gender identity disorders mental disorders Both 0.929 1.0 0.923,1.09 608 6055 0.6353 1.03 0.915,1.16 313 3168
302.1 Decreased libido mental disorders Both 0.5358 1.04 0.924,1.16 325 3233 0.6353 1.03 0.915,1.16 313 3168
303 Psychogenic and somatoform disorders mental disorders Both 0.4989 1.02 0.959,1.09 1030 10064 0.1416 1.05 0.983,1.13 898 8935
303.1 Dissociative disorder mental disorders Both 0.8995 0.988 0.817,1.19 115 1144 0.877 1.02 0.836,1.23 109 1117
303.3 Psychogenic disorder mental disorders Both 0.3499 1.04 0.962,1.12 736 7330 0.4198 1.05 0.936,1.17 333 3323
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.3733 1.05 0.941,1.18 340 3376 0.4198 1.05 0.936,1.17 333 3323
303.4 Somatoform disorder mental disorders Both 0.1393 1.05 0.984,1.13 925 9106 0.1416 1.05 0.983,1.13 898 8935
304 Adjustment reaction mental disorders Both 0.877 1.0 0.964,1.04 2840 17464 0.8147 0.995 0.955,1.04 2723 17128
305.2 Eating disorder mental disorders Both 0.4977 0.972 0.896,1.05 650 6500 0.3648 0.963 0.887,1.05 634 6389
306 Other mental disorder mental disorders Both 0.4624 1.02 0.964,1.08 1254 10907 0.1239 0.93 0.847,1.02 496 5115
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.9376 1.0 0.906,1.11 418 2847 0.8395 1.01 0.911,1.12 413 2804
306.9 Tension headache mental disorders Both 0.1143 0.929 0.849,1.02 521 5210 0.1239 0.93 0.847,1.02 496 5115
312 Conduct disorders mental disorders Both 0.4169 1.06 0.918,1.23 189 1890 0.09772 1.27 0.956,1.7 53 519
312.3 Impulse control disorder mental disorders Both 0.1 1.27 0.955,1.69 53 530 0.09772 1.27 0.956,1.7 53 519
313 Pervasive developmental disorders mental disorders Both 0.6918 0.988 0.929,1.05 1148 11078 0.01514 0.7 0.525,0.933 56 585
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.9311 1.0 0.94,1.07 1012 9899 0.8204 0.992 0.93,1.06 985 9701
313.2 Tics and stuttering mental disorders Both 0.03631 0.746 0.568,0.981 60 593 0.01514 0.7 0.525,0.933 56 585
315 Develomental delays and disorders mental disorders Both 0.3864 1.05 0.944,1.16 401 3990 0.743 1.03 0.862,1.23 134 1760
315.1 Learning disorder mental disorders Both 0.8128 0.97 0.755,1.25 60 599 0.4178 0.894 0.682,1.17 51 590
315.2 Speech and language disorder mental disorders Both 0.4645 1.06 0.908,1.24 182 1801 0.743 1.03 0.862,1.23 134 1760
316 Substance addiction and disorders mental disorders Both 0.9954 1.0 0.962,1.04 2799 26014 0.537 0.971 0.885,1.07 483 5079
316.1 Polyneuropathy due to drugs mental disorders Both 0.9506 0.997 0.912,1.09 518 5180 0.537 0.971 0.885,1.07 483 5079
317 Alcohol-related disorders mental disorders Both 0.8091 1.01 0.96,1.05 1948 17547 0.7047 1.02 0.915,1.14 333 3260
317.1 Alcoholism mental disorders Both 0.9057 0.997 0.946,1.05 1517 14733 0.7047 1.02 0.915,1.14 333 3260
317.11 Alcoholic liver damage mental disorders Both 0.597 1.03 0.923,1.15 335 3336 0.7047 1.02 0.915,1.14 333 3260
318 Tobacco use disorder mental disorders Both 0.6808 0.995 0.972,1.02 9473 26924 0.7674 0.996 0.973,1.02 9170 26382
320 Meningitis neurological Both 0.175 1.08 0.966,1.21 319 3181 0.08128 1.11 0.987,1.25 280 3097
323 Encephalitis neurological Both 0.5248 1.05 0.896,1.24 148 1475 0.8954 1.01 0.837,1.23 115 1220
323.8 Encephalitis, non-infectious neurological Both 0.8241 1.02 0.851,1.23 125 1245 0.8954 1.01 0.837,1.23 115 1220
324 Other CNS infection and poliomyelitis neurological Both 0.2317 1.08 0.951,1.23 245 2440 0.2495 1.08 0.945,1.24 216 2378
327 Sleep disorders neurological Both 0.02818 0.976 0.954,0.997 11517 26652 0.1778 0.828 0.629,1.09 53 530
327.1 Hypersomnia neurological Both 0.01413 0.933 0.883,0.986 1403 13919 0.01445 0.933 0.882,0.986 1365 13625
327.3 Sleep apnea neurological Both 0.0123 0.969 0.945,0.993 8293 26193 0.06607 0.974 0.948,1.0 6379 24982
327.31 Central/nonobstroctive sleep apnea neurological Both 0.7015 1.02 0.913,1.14 326 3234 0.4295 1.05 0.934,1.17 315 3161
327.32 Obstructive sleep apnea neurological Both 0.05129 0.973 0.947,1.0 6534 25537 0.06607 0.974 0.948,1.0 6379 24982
327.4 Insomnia neurological Both 0.6592 0.993 0.961,1.03 4197 25860 0.4943 0.976 0.909,1.05 857 8542
327.41 Organic or persistent insomnia neurological Both 0.415 0.971 0.906,1.04 881 8743 0.4943 0.976 0.909,1.05 857 8542
327.5 Parasomnia neurological Both 0.5458 0.971 0.883,1.07 459 4583 0.5058 0.968 0.879,1.07 446 4491
327.6 Circadian rhythm sleep disorder neurological Both 0.9572 0.996 0.85,1.17 174 1738 0.9078 0.991 0.845,1.16 170 1702
327.7 Sleep related movement disorders neurological Both 0.1416 0.959 0.907,1.01 1364 13620 0.1778 0.828 0.629,1.09 53 530
327.71 Restless legs syndrome neurological Both 0.3236 0.971 0.915,1.03 1214 12132 0.2371 0.964 0.908,1.02 1189 11848
327.72 Sleep related leg cramps neurological Both 0.1178 0.804 0.612,1.06 55 550 0.1778 0.828 0.629,1.09 53 530
331 Other cerebral degenerations neurological Both 0.2084 1.05 0.971,1.14 602 5935 0.173 1.08 0.966,1.21 315 3408
331.1 Hydrocephalus neurological Both 0.2618 0.927 0.813,1.06 246 2447 0.08511 0.87 0.742,1.02 163 2430
331.9 Cerebral degeneration, unspecified neurological Both 0.1219 1.09 0.977,1.21 349 3423 0.173 1.08 0.966,1.21 315 3408
332 Parkinson's disease neurological Both 0.7079 1.02 0.913,1.14 333 3321 0.9727 0.998 0.889,1.12 323 3296
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.873 0.996 0.953,1.04 2169 20920 0.8995 1.02 0.79,1.31 64 637
333.1 Essential tremor neurological Both 0.867 1.01 0.922,1.1 551 5488 0.9931 1.0 0.914,1.1 533 5461
333.2 Myoclonus neurological Both 0.9931 0.999 0.828,1.21 117 1160 0.7745 0.972 0.798,1.18 106 1155
333.4 Torsion dystonia neurological Both 0.2118 1.08 0.956,1.23 266 2646 0.3548 1.06 0.935,1.21 254 2634
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.8995 1.02 0.79,1.31 64 640 0.8995 1.02 0.79,1.31 64 637
334 Degenerative disease of the spinal cord neurological Both 0.5848 1.02 0.951,1.09 874 8734 0.9795 0.996 0.754,1.32 54 568
334.1 Spinocerebellar disease neurological Both 0.7762 0.964 0.747,1.24 64 631 0.5559 0.919 0.693,1.22 51 627
334.2 Anterior horn cell disease neurological Both 0.7962 1.03 0.834,1.27 92 920 0.9795 0.996 0.754,1.32 54 568
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.7096 1.05 0.807,1.37 57 570 0.9795 0.996 0.754,1.32 54 568
335 Multiple sclerosis neurological Both 0.4416 0.956 0.852,1.07 330 3284 0.4446 0.956 0.85,1.07 318 3265
337 Disorders of the autonomic nervous system neurological Both 0.1726 1.06 0.973,1.16 528 5257 0.03548 1.17 1.01,1.37 179 1828
337.1 Peripheral autonomic neuropathy neurological Both 0.05012 1.16 1.0,1.34 185 1837 0.03548 1.17 1.01,1.37 179 1828
338 Pain neurological Both 0.8933 0.999 0.979,1.02 16189 22165 0.7328 0.996 0.97,1.02 8042 21780
338.1 Acute pain neurological Both 0.9594 1.0 0.979,1.02 12567 22166 0.9954 1.0 0.978,1.02 12097 21792
338.2 Chronic pain neurological Both 0.5272 0.992 0.967,1.02 8223 22154 0.7328 0.996 0.97,1.02 8042 21780
339 Other headache syndromes neurological Both 0.8147 0.997 0.973,1.02 8578 27793 0.7943 0.997 0.972,1.02 8154 27349
340 Migraine neurological Both 0.7161 0.994 0.965,1.02 5377 24263 0.5129 1.01 0.974,1.05 2794 18376
340.1 Migrain with aura neurological Both 0.7161 1.01 0.968,1.05 2862 18665 0.5129 1.01 0.974,1.05 2794 18376
341 Other demyelinating diseases of central nervous system neurological Both 0.2399 0.887 0.727,1.08 111 1105 0.2884 0.895 0.73,1.1 106 1102
342 Hemiplegia neurological Both 0.01778 1.14 1.02,1.27 360 3589 0.6281 1.03 0.911,1.17 269 3576
343 Infantile cerebral palsy neurological Both 0.8892 1.02 0.8,1.29 75 750 0.8974 1.02 0.796,1.3 72 743
344 Other paralytic syndromes neurological Both 0.5321 0.973 0.891,1.06 564 5640 0.7798 0.987 0.901,1.08 517 5604
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.6918 1.01 0.965,1.06 2084 20790 0.2786 0.973 0.925,1.02 1663 19513
345.1 Epilepsy neurological Both 0.6887 0.983 0.904,1.07 607 6053 0.2673 0.937 0.836,1.05 314 4311
345.11 Generalized convulsive epilepsy neurological Both 0.826 1.02 0.88,1.17 196 1960 0.8851 1.01 0.867,1.18 170 1954
345.12 Partial epilepsy neurological Both 0.4064 0.959 0.869,1.06 434 4333 0.2673 0.937 0.836,1.05 314 4311
345.3 Convulsions neurological Both 0.7031 1.01 0.963,1.06 1967 19598 0.2786 0.973 0.925,1.02 1663 19513
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.2606 1.1 0.93,1.31 142 1404 0.3281 0.886 0.694,1.13 71 880
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.4064 1.03 0.966,1.09 1196 11927 0.9057 0.996 0.934,1.06 1018 11872
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.9099 0.987 0.794,1.23 87 860 0.6266 0.942 0.741,1.2 71 860
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.2761 0.886 0.713,1.1 90 884 0.3281 0.886 0.694,1.13 71 880
347 Cataplexy and narcolepsy neurological Both 0.7745 0.964 0.752,1.24 67 670 0.5916 0.933 0.724,1.2 65 666
348 Other conditions of brain neurological Both 0.169 1.04 0.984,1.1 1424 14226 0.1535 1.04 0.985,1.1 1384 19889
348.2 Cerebral edema and compression of brain neurological Both 0.2624 1.04 0.969,1.12 747 7463 0.03162 0.892 0.804,0.99 380 7430
348.4 Cerebral cysts neurological Both 0.9333 1.01 0.871,1.16 195 1945 0.8318 1.02 0.866,1.2 151 1937
348.7 Coma neurological Both 0.01413 1.22 1.04,1.43 162 1620 0.02884 1.2 1.02,1.42 150 1616
348.8 Encephalopathy, not elsewhere classified neurological Both 0.9183 1.0 0.927,1.09 636 6331 0.5715 0.975 0.894,1.06 538 6299
348.9 Other conditions of brain, NOS neurological Both 0.001349 1.08 1.03,1.13 2001 19979 0.1535 1.04 0.985,1.1 1384 19889
349 Other and unspecified disorders of the nervous system neurological Both 0.1667 1.05 0.979,1.13 775 7750 0.2844 1.04 0.966,1.13 689 7707
350 Abnormal movement neurological Both 0.9727 0.999 0.97,1.03 5109 32314 0.9162 1.01 0.909,1.11 419 4412
350.1 Abnormal involuntary movements neurological Both 0.6607 1.01 0.968,1.05 2464 24243 0.7727 1.01 0.965,1.05 2354 23832
350.2 Abnormality of gait neurological Both 0.5916 0.99 0.953,1.03 2979 25007 0.2917 0.979 0.941,1.02 2755 24571
350.3 Lack of coordination neurological Both 0.3565 0.966 0.897,1.04 773 7693 0.4529 0.971 0.9,1.05 709 7559
350.5 Abnormal reflex neurological Both 0.08128 1.16 0.981,1.37 143 1430 0.1268 1.14 0.963,1.35 136 1398
350.6 Disturbances of sensation of smell and taste neurological Both 0.7047 1.02 0.924,1.12 448 4480 0.9162 1.01 0.909,1.11 419 4412
351 Other peripheral nerve disorders neurological Both 0.618 0.993 0.965,1.02 5685 28844 0.7745 0.996 0.967,1.03 5554 28205
352 Disorders of other cranial nerves neurological Both 0.5546 1.02 0.963,1.07 1412 14120 0.414 0.965 0.887,1.05 575 6252
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.5058 1.03 0.938,1.14 440 4393 0.3342 1.05 0.951,1.16 409 4283
352.2 Facial nerve disorders [CN7] neurological Both 0.2864 0.957 0.883,1.04 640 6400 0.414 0.965 0.887,1.05 575 6252
353 Nerve root and plexus disorders neurological Both 0.5929 1.01 0.974,1.05 3295 28097 0.02089 1.27 1.04,1.56 89 911
353.1 Nerve plexus lesions neurological Both 0.9863 1.0 0.892,1.12 308 3077 0.9141 1.01 0.896,1.13 302 3010
353.2 Nerve root lesions neurological Both 0.01738 1.28 1.04,1.56 94 930 0.02089 1.27 1.04,1.56 89 911
355 Complex regional/central pain syndrome neurological Both 0.912 1.01 0.909,1.11 419 4170 0.9247 1.0 0.926,1.09 638 6350
355.1 Chronic pain syndrome neurological Both 0.9141 0.996 0.92,1.08 654 6509 0.9247 1.0 0.926,1.09 638 6350
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.7516 1.01 0.959,1.06 1728 17176 0.871 1.0 0.955,1.06 1668 16784
357 Inflammatory and toxic neuropathy neurological Both 0.4285 1.02 0.976,1.06 2467 24091 0.6266 1.01 0.969,1.05 2377 23558
358 Myoneural disorders neurological Both 0.235 1.04 0.973,1.12 845 8441 0.7362 0.964 0.776,1.2 84 825
358.1 Myasthenia gravis neurological Both 0.8933 0.985 0.795,1.22 85 850 0.7362 0.964 0.776,1.2 84 825
359 Muscular dystrophies and other myopathies neurological Both 0.4634 0.974 0.908,1.04 868 8655 0.302 0.962 0.894,1.04 783 8136
359.1 Muscular dystrophies neurological Both 0.1 1.27 0.956,1.68 52 520 0.1426 1.24 0.931,1.64 51 506
359.2 Myopathy neurological Both 0.3436 0.966 0.9,1.04 833 8306 0.302 0.962 0.894,1.04 783 8136
360 Disorders of the globe sense organs Both 0.2512 1.13 0.918,1.38 102 1013 0.3954 1.1 0.888,1.35 99 987
361 Retinal detachments and defects sense organs Both 0.104 1.08 0.985,1.18 528 5265 0.278 1.08 0.94,1.24 216 2182
361.1 Retinal detachment with retinal defect sense organs Both 0.2523 1.08 0.945,1.24 225 2226 0.278 1.08 0.94,1.24 216 2182
362 Other retinal disorders sense organs Both 0.9886 1.0 0.959,1.04 2489 18838 0.5333 1.05 0.905,1.21 196 1959
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.7727 1.01 0.955,1.06 1529 12328 0.8892 1.0 0.947,1.06 1284 10692
362.21 Macular degeneration, dry sense organs Both 0.5821 0.968 0.862,1.09 313 2650 0.4831 0.958 0.851,1.08 301 2592
362.22 Macular degeneration, wet sense organs Both 0.2371 1.13 0.924,1.38 108 881 0.2254 1.13 0.926,1.39 105 868
362.23 Cystoid macular degeneration of retina sense organs Both 0.6982 0.976 0.863,1.1 285 2777 0.7295 0.978 0.864,1.11 279 2720
362.26 Macular puckering of retina sense organs Both 0.6166 1.02 0.942,1.11 645 6254 0.7031 1.02 0.936,1.1 627 6117
362.27 Drusen (degenerative) of retina sense organs Both 0.3266 1.06 0.945,1.18 335 3205 0.3819 1.05 0.939,1.18 325 3136
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.8318 1.01 0.95,1.07 1323 10928 0.8892 1.0 0.947,1.06 1284 10692
362.3 Other nondiabetic retinopathy sense organs Both 0.3899 0.965 0.891,1.05 653 6476 0.9268 0.994 0.882,1.12 287 2868
362.31 Separation of retinal layers sense organs Both 0.9036 0.993 0.882,1.12 296 2938 0.9268 0.994 0.882,1.12 287 2868
362.4 Retinal vascular changes and abnomalities sense organs Both 0.975 0.998 0.906,1.1 449 4295 0.8166 1.01 0.917,1.12 435 4199
362.6 Peripheral retinal degenerations sense organs Both 0.1629 1.09 0.965,1.24 262 2600 0.1845 1.09 0.961,1.23 259 2537
362.7 Hereditary retinal dystrophies sense organs Both 0.01479 1.24 1.04,1.48 124 1233 0.01047 1.26 1.06,1.51 116 1207
362.8 Retinal hemorrhage/ischemia sense organs Both 0.195 0.899 0.766,1.06 160 1570 0.2143 0.902 0.767,1.06 157 1536
362.9 Retinal edema sense organs Both 0.561 1.04 0.903,1.21 202 2001 0.5333 1.05 0.905,1.21 196 1959
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.975 0.998 0.896,1.11 375 3665 0.7194 0.976 0.855,1.11 241 2380
363.3 Chorioretinal scars sense organs Both 0.5781 0.964 0.846,1.1 249 2430 0.7194 0.976 0.855,1.11 241 2380
364 Corneal opacity and other disorders of cornea sense organs Both 0.7762 1.01 0.94,1.09 809 7919 0.5781 1.07 0.839,1.37 67 669
364.1 Corneal opacity sense organs Both 0.6223 1.03 0.915,1.16 294 2930 0.6761 1.03 0.909,1.16 284 2849
364.2 Corneal edema sense organs Both 0.3412 0.894 0.71,1.13 84 819 0.309 0.886 0.702,1.12 83 798
364.4 Corneal degenerations sense organs Both 0.9594 0.997 0.88,1.13 274 2719 0.9954 1.0 0.88,1.14 261 2653
364.5 Corneal dystrophy sense organs Both 0.3334 1.05 0.948,1.17 377 3673 0.5395 1.05 0.906,1.21 202 1964
364.51 Fuchs' dystrophy sense organs Both 0.3639 1.07 0.927,1.23 207 2008 0.5395 1.05 0.906,1.21 202 1964
364.9 Cornea replaced by transplant sense organs Both 0.5105 1.08 0.851,1.38 69 677 0.5781 1.07 0.839,1.37 67 669
365 Glaucoma sense organs Both 0.6776 0.99 0.945,1.04 1986 17152 0.2838 1.09 0.933,1.27 174 1663
365.1 Open-angle glaucoma sense organs Both 0.1067 0.927 0.846,1.02 523 4963 0.1285 0.907 0.8,1.03 274 2550
365.11 Primary open angle glaucoma sense organs Both 0.1047 0.902 0.797,1.02 281 2609 0.1285 0.907 0.8,1.03 274 2550
365.2 Primary angle-closure glaucoma sense organs Both 0.2432 1.09 0.941,1.27 179 1707 0.2838 1.09 0.933,1.27 174 1663
366 Cataract sense organs Both 0.138 0.978 0.95,1.01 6335 23476 0.865 0.997 0.962,1.03 3730 19931
366.1 Nonsenile Cataract sense organs Both 0.07413 0.858 0.726,1.02 163 1622 0.07244 0.856 0.722,1.01 158 1587
366.2 Senile cataract sense organs Both 0.9506 0.999 0.964,1.03 3827 20410 0.865 0.997 0.962,1.03 3730 19931
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.6124 1.01 0.98,1.03 6553 31745 0.9247 0.997 0.932,1.07 910 9441
367.1 Myopia sense organs Both 0.5284 0.989 0.955,1.02 3578 28818 0.5808 0.99 0.956,1.03 3501 28166
367.2 Astigmatism sense organs Both 0.9817 1.0 0.963,1.04 2892 26106 0.7925 1.01 0.967,1.05 2831 25499
367.4 Presbyopia sense organs Both 0.7396 0.994 0.958,1.03 3297 24582 0.6855 0.992 0.956,1.03 3229 24005
367.8 Hypermetropia sense organs Both 0.9705 0.999 0.948,1.05 1504 14729 0.9397 0.998 0.946,1.05 1461 14413
367.9 Blindness and low vision sense organs Both 0.9397 0.997 0.935,1.06 976 9663 0.9247 0.997 0.932,1.07 910 9441
368 Visual disturbances sense organs Both 0.7998 0.996 0.965,1.03 4287 32818 0.06026 1.24 0.991,1.54 83 866
368.1 Amblyopia sense organs Both 0.3846 1.04 0.949,1.14 484 4830 0.4236 1.04 0.945,1.14 463 4734
368.2 Diplopia and disorders of binocular vision sense organs Both 0.7228 0.987 0.92,1.06 822 8186 0.4256 0.97 0.9,1.05 732 8040
368.3 Anisometropia sense organs Both 0.9908 1.0 0.855,1.17 166 1648 0.9705 0.997 0.85,1.17 164 1623
368.4 Visual field defects sense organs Both 0.6368 1.02 0.948,1.09 879 8777 0.5176 0.976 0.905,1.05 770 8617
368.9 Subjective visual disturbances sense organs Both 0.3013 0.963 0.896,1.03 829 8268 0.06026 1.24 0.991,1.54 83 866
368.91 Psychophysical visual disturbances sense organs Both 0.05129 1.24 0.999,1.54 89 885 0.06026 1.24 0.991,1.54 83 866
369 Infection of the eye sense organs Both 0.2291 0.974 0.933,1.02 2328 22262 0.4395 0.982 0.937,1.03 1933 18987
369.2 Eye infection, viral sense organs Both 0.8453 0.989 0.889,1.1 372 3688 0.929 1.0 0.902,1.12 363 3619
369.5 Conjunctivitis, infectious sense organs Both 0.413 0.981 0.936,1.03 1974 19408 0.4395 0.982 0.937,1.03 1933 18987
370 Keratitis sense organs Both 0.3606 1.03 0.967,1.1 1051 10280 0.1432 1.14 0.958,1.35 146 1404
370.1 Corneal ulcer sense organs Both 0.02818 0.832 0.706,0.981 164 1630 0.0955 0.868 0.734,1.03 156 1602
370.2 Superficial keratitis sense organs Both 0.798 0.987 0.89,1.09 394 3916 0.8492 0.99 0.891,1.1 381 3842
370.3 Keratoconjunctivitis sense organs Both 0.00302 1.14 1.05,1.25 531 5159 0.1432 1.14 0.958,1.35 146 1404
370.31 Keratoconjunctivitis sicca sense organs Both 0.1216 1.14 0.965,1.35 150 1432 0.1432 1.14 0.958,1.35 146 1404
371 Inflammation of the eye sense organs Both 0.1429 0.973 0.938,1.01 3269 26161 0.3199 0.901 0.733,1.11 99 963
371.1 Uveitis, noninfectious or NOS sense organs Both 0.4083 1.04 0.942,1.16 394 3892 0.4498 1.04 0.938,1.16 380 3817
371.2 Conjunctivitis, noninfectious sense organs Both 0.02455 0.912 0.842,0.988 651 6462 0.06026 0.918 0.84,1.0 524 5158
371.21 Allergic conjunctivitis sense organs Both 0.0389 0.911 0.834,0.995 532 5279 0.06026 0.918 0.84,1.0 524 5158
371.3 Inflammation of eyelids sense organs Both 0.3273 0.979 0.939,1.02 2523 21781 0.3199 0.901 0.733,1.11 99 963
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.3119 0.899 0.732,1.1 100 979 0.3199 0.901 0.733,1.11 99 963
372 Disorders of conjunctiva sense organs Both 0.3673 1.03 0.962,1.11 827 8153 0.4295 1.03 0.958,1.11 798 7980
374 Other disorders of eyelids sense organs Both 0.7889 1.01 0.962,1.05 2093 18512 0.1132 0.94 0.87,1.01 734 7247
374.1 Ectropion or entropion sense organs Both 0.7551 1.02 0.911,1.14 337 3251 0.9057 1.01 0.898,1.13 318 3183
374.2 Lagophthalmos sense organs Both 0.8017 1.02 0.883,1.18 192 1900 0.8185 0.983 0.845,1.14 170 1862
374.3 Ptosis of eyelid sense organs Both 0.4477 0.973 0.905,1.04 817 8140 0.2489 0.957 0.889,1.03 762 7952
374.6 Dermatochalasis sense organs Both 0.2004 0.952 0.882,1.03 759 7426 0.1132 0.94 0.87,1.01 734 7247
375 Disorders of lacrimal system sense organs Both 0.6209 1.01 0.97,1.05 2683 21054 0.869 0.991 0.886,1.11 337 3481
375.1 Dry eyes sense organs Both 0.5224 1.01 0.974,1.05 2966 21823 0.4457 1.02 0.976,1.06 2877 21395
375.2 Epiphora sense organs Both 0.6607 0.976 0.876,1.09 356 3540 0.869 0.991 0.886,1.11 337 3481
376 Disorders of the orbit sense organs Both 0.859 1.01 0.897,1.14 285 2814 0.9078 1.01 0.891,1.14 266 2768
377 Disorders of optic nerve and visual pathways sense organs Both 0.5346 1.02 0.949,1.11 706 7010 0.9638 1.0 0.906,1.11 401 4532
377.1 Optic atrophy sense organs Both 0.3589 0.934 0.808,1.08 200 1997 0.4121 0.939 0.809,1.09 187 1961
377.3 Optic neuritis/neuropathy sense organs Both 0.8318 1.01 0.92,1.11 468 4627 0.9638 1.0 0.906,1.11 401 4532
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.7798 1.01 0.945,1.08 969 9602 0.3926 0.942 0.821,1.08 218 2663
378.1 Strabismus (not specified as paralytic) sense organs Both 0.5715 0.977 0.9,1.06 617 6131 0.6442 0.98 0.9,1.07 571 6006
378.2 Nystagmus and other irregular eye movements sense organs Both 0.03388 1.22 1.02,1.46 138 1371 0.0182 1.27 1.04,1.54 113 1342
378.5 Paralytic strabismus sense organs Both 0.3319 0.941 0.832,1.06 275 2720 0.3926 0.942 0.821,1.08 218 2663
379 Other disorders of eye sense organs Both 0.7129 1.01 0.972,1.04 3593 24835 0.5 1.02 0.954,1.1 835 8437
379.1 Scleritis and episcleritis sense organs Both 0.7464 1.03 0.868,1.22 140 1379 0.7161 1.03 0.869,1.23 136 1350
379.2 Disorders of vitreous body sense organs Both 0.3034 1.02 0.98,1.07 2559 18709 0.3945 1.02 0.976,1.06 2492 18356
379.3 Aphakia and other disorders of lens sense organs Both 0.7568 0.966 0.777,1.2 87 838 0.8974 0.986 0.79,1.23 84 815
379.4 Anomalies of pupillary function sense organs Both 0.5284 0.958 0.839,1.09 231 2303 0.2415 0.92 0.801,1.06 212 2271
379.5 Disorders of iris and ciliary body sense organs Both 0.871 1.01 0.88,1.16 215 2128 0.6223 1.07 0.823,1.38 61 597
379.51 Pigmentary iris degeneration sense organs Both 0.6397 1.06 0.82,1.38 61 610 0.6223 1.07 0.823,1.38 61 597
379.9 Pain, swelling or discharge of eye sense organs Both 0.5272 1.02 0.954,1.1 870 8594 0.5 1.02 0.954,1.1 835 8437
380 Disorders of external ear sense organs Both 0.03311 1.06 1.0,1.11 1634 15553 0.3963 1.02 0.974,1.07 1924 18193
380.1 Otitis externa sense organs Both 0.3076 1.03 0.971,1.1 1124 11213 0.2128 1.04 0.978,1.11 1086 10952
380.4 Impacted cerumen sense organs Both 0.5082 1.02 0.97,1.06 1985 18630 0.3963 1.02 0.974,1.07 1924 18193
381 Otitis media and Eustachian tube disorders sense organs Both 0.1607 1.03 0.99,1.06 3291 29339 0.2904 1.07 0.946,1.2 279 2890
381.1 Otitis media sense organs Both 0.1153 1.03 0.992,1.08 2402 23549 0.1377 1.04 0.989,1.08 1948 19717
381.11 Suppurative and unspecified otitis media sense organs Both 0.1285 1.04 0.99,1.08 2037 20175 0.1377 1.04 0.989,1.08 1948 19717
381.2 Eustachian tube disorders sense organs Both 0.2786 1.03 0.976,1.09 1393 13815 0.1854 1.04 0.982,1.1 1360 13512
381.3 Mastoiditis & related conditions sense organs Both 0.0182 0.802 0.668,0.963 126 1260 0.05248 0.831 0.69,1.0 119 1225
381.9 Otorrhea sense organs Both 0.4426 1.05 0.931,1.18 297 2960 0.2904 1.07 0.946,1.2 279 2890
382 Otalgia sense organs Both 0.9036 1.0 0.95,1.06 1425 14188 0.7447 1.01 0.955,1.07 1390 13887
383 Otosclerosis sense organs Both 0.0195 1.27 1.04,1.55 112 1120 0.01862 1.28 1.04,1.56 110 1092
384 Other disorders of tympanic membrane sense organs Both 0.6776 0.979 0.884,1.08 397 3962 0.5741 1.03 0.919,1.16 303 3115
384.4 Perforation of tympanic membrane sense organs Both 0.6683 1.03 0.914,1.15 318 3180 0.5741 1.03 0.919,1.16 303 3115
385 Other disorders of middle ear and mastoid sense organs Both 0.7745 0.984 0.882,1.1 358 3580 0.8954 0.986 0.802,1.21 102 1007
385.3 Cholesteatoma sense organs Both 0.9036 0.992 0.869,1.13 245 2450 0.9954 1.0 0.875,1.14 238 2398
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.8472 0.98 0.797,1.2 103 1025 0.8954 0.986 0.802,1.21 102 1007
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.455 0.979 0.928,1.03 1441 14255 0.6998 1.01 0.976,1.04 5087 30961
386.1 Meniere's disease sense organs Both 0.1368 0.904 0.791,1.03 248 2464 0.1151 0.897 0.783,1.03 242 2418
386.2 Peripheral or central vertigo sense organs Both 0.4074 0.975 0.919,1.03 1209 11971 0.929 0.997 0.929,1.07 858 8575
386.21 Central origin vertigo sense organs Both 0.955 0.998 0.931,1.07 883 8759 0.929 0.997 0.929,1.07 858 8575
386.3 Labyrinthitis sense organs Both 0.811 1.01 0.947,1.07 1099 10904 0.9484 1.0 0.94,1.07 1053 10675
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.5105 1.01 0.981,1.04 5315 31605 0.6998 1.01 0.976,1.04 5087 30961
388 Other disorders of ear sense organs Both 0.857 0.993 0.918,1.07 699 6960 0.9354 1.0 0.926,1.09 668 6806
389 Hearing loss sense organs Both 0.3467 1.01 0.986,1.04 6285 31750 0.6252 1.06 0.848,1.32 92 983
389.1 Sensorineural hearing loss sense organs Both 0.03802 1.04 1.0,1.08 3130 24231 0.0257 1.04 1.01,1.09 2978 23726
389.2 Conductive hearing loss sense organs Both 0.06026 1.08 0.997,1.16 717 7169 0.04365 1.08 1.0,1.17 696 7031
389.3 Degenerative and vascular disorders of ear sense organs Both 0.4721 0.938 0.789,1.12 143 1338 0.3707 0.923 0.773,1.1 140 1309
389.4 Tinnitus sense organs Both 0.9705 1.0 0.952,1.05 1677 16701 0.8892 1.0 0.953,1.06 1606 16381
389.5 Disorders of acoustic nerve sense organs Both 0.5943 1.06 0.858,1.31 101 1010 0.6252 1.06 0.848,1.32 92 983
394 Rheumatic disease of the heart valves circulatory system Both 0.6637 1.01 0.954,1.08 1177 11253 0.9311 1.0 0.913,1.1 460 4509
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.0912 1.11 0.984,1.25 284 2766 0.04898 1.13 1.0,1.28 276 2688
394.2 Mitral valve disease circulatory system Both 0.6546 1.02 0.922,1.14 378 3735 0.6887 1.02 0.918,1.14 371 3649
394.3 Aortic valve disease circulatory system Both 0.4093 1.07 0.911,1.26 150 1465 0.3214 1.09 0.923,1.28 147 1422
394.7 Disease of tricuspid valve circulatory system Both 0.9057 0.994 0.904,1.09 468 4624 0.9311 1.0 0.913,1.1 460 4509
395 Heart valve disorders circulatory system Both 0.695 1.01 0.971,1.05 3169 23926 0.9484 1.0 0.935,1.07 863 7995
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.3365 1.02 0.975,1.08 1754 16787 0.3148 1.03 0.976,1.08 1723 16389
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.8128 0.994 0.944,1.05 1619 13932 0.9099 0.997 0.946,1.05 1592 13545
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.778 1.02 0.913,1.13 373 3704 0.6823 1.02 0.919,1.14 370 3628
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.1371 1.19 0.947,1.49 84 831 0.08318 1.22 0.974,1.54 83 811
395.6 Heart valve replaced circulatory system Both 0.8241 0.992 0.926,1.06 878 8213 0.9484 1.0 0.935,1.07 863 7995
396 Abnormal heart sounds circulatory system Both 0.826 1.0 0.97,1.04 3754 28453 0.7603 1.01 0.971,1.04 3671 27751
401 Hypertension circulatory system Both 0.9817 1.0 0.977,1.02 18784 19071 0.8954 0.997 0.95,1.05 1961 12674
401.1 Essential hypertension circulatory system Both 0.912 0.999 0.976,1.02 18655 19070 0.7962 0.997 0.974,1.02 18179 18657
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.6839 0.991 0.947,1.04 2599 12045 0.6124 0.987 0.939,1.04 1957 10655
401.21 Hypertensive heart disease circulatory system Both 0.9247 1.0 0.919,1.1 556 4628 0.9419 1.0 0.917,1.1 542 4526
401.22 Hypertensive chronic kidney disease circulatory system Both 0.6383 0.988 0.941,1.04 2015 10909 0.6124 0.987 0.939,1.04 1957 10655
401.3 Other hypertensive complications circulatory system Both 0.9705 1.0 0.954,1.05 2027 12961 0.8954 0.997 0.95,1.05 1961 12674
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.9772 0.999 0.955,1.05 2132 15248 0.9162 1.0 0.957,1.05 2084 14901
411 Ischemic Heart Disease circulatory system Both 0.1991 0.982 0.955,1.01 6970 25468 0.2748 1.07 0.951,1.19 321 3168
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.08511 0.933 0.863,1.01 702 6842 0.08128 0.932 0.861,1.01 693 6672
411.2 Myocardial infarction circulatory system Both 0.5105 0.987 0.948,1.03 2849 17983 0.6124 0.99 0.95,1.03 2795 17540
411.3 Angina pectoris circulatory system Both 0.07079 0.957 0.912,1.0 1904 15218 0.118 0.962 0.917,1.01 1858 14837
411.4 Coronary atherosclerosis circulatory system Both 0.06761 0.972 0.943,1.0 5938 22890 0.05888 0.829 0.683,1.01 114 1122
411.41 Aneurysm and dissection of heart circulatory system Both 0.1227 0.861 0.711,1.04 117 1149 0.05888 0.829 0.683,1.01 114 1122
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.1096 0.974 0.943,1.01 4877 21174 0.139 0.975 0.944,1.01 4775 20653
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.2564 1.07 0.954,1.19 335 3247 0.2748 1.07 0.951,1.19 321 3168
414 Other forms of chronic heart disease circulatory system Both 0.3013 0.977 0.936,1.02 2360 18485 0.3112 0.953 0.868,1.05 483 4714
414.2 ASCVD circulatory system Both 0.3273 0.955 0.87,1.05 492 4846 0.3112 0.953 0.868,1.05 483 4714
415 Pulmonary heart disease circulatory system Both 0.3664 0.982 0.944,1.02 2726 25061 0.673 0.982 0.902,1.07 583 5762
415.1 Acute pulmonary heart disease circulatory system Both 0.4688 0.981 0.93,1.03 1510 15045 0.3622 0.975 0.923,1.03 1428 14661
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.4487 0.98 0.929,1.03 1507 15014 0.3622 0.975 0.923,1.03 1428 14661
415.2 Chronic pulmonary heart disease circulatory system Both 0.5321 0.983 0.933,1.04 1506 14839 0.673 0.982 0.902,1.07 583 5762
415.21 Primary pulmonary hypertension circulatory system Both 0.6412 0.98 0.901,1.07 592 5901 0.673 0.982 0.902,1.07 583 5762
416 Cardiomegaly circulatory system Both 0.879 0.995 0.93,1.06 935 9293 0.811 0.992 0.927,1.06 917 9072
418 Nonspecific chest pain circulatory system Both 0.1923 0.985 0.962,1.01 10015 28233 0.4027 0.974 0.917,1.04 1160 11524
418.1 Precordial pain circulatory system Both 0.3873 0.974 0.917,1.03 1193 11816 0.4027 0.974 0.917,1.04 1160 11524
420 Carditis circulatory system Both 0.9183 1.0 0.947,1.06 1275 12633 0.8072 1.01 0.93,1.1 593 5848
420.1 Myocarditis circulatory system Both 0.3483 1.11 0.888,1.4 76 752 0.5129 1.08 0.856,1.36 73 738
420.2 Pericarditis circulatory system Both 0.826 0.991 0.917,1.07 684 6830 0.3556 0.901 0.722,1.12 87 892
420.21 Acute pericarditis circulatory system Both 0.0912 0.862 0.726,1.02 144 1435 0.08128 0.856 0.719,1.02 139 1400
420.22 Chronic pericarditis circulatory system Both 0.1888 0.864 0.695,1.07 92 912 0.3556 0.901 0.722,1.12 87 892
420.3 Endocarditis circulatory system Both 0.8128 1.01 0.93,1.1 602 5990 0.8072 1.01 0.93,1.1 593 5848
425 Cardiomyopathy circulatory system Both 0.2812 1.03 0.977,1.08 1617 15758 0.871 1.02 0.797,1.31 67 690
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.2506 1.03 0.979,1.09 1557 15170 0.2366 1.1 0.938,1.3 151 1509
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.1607 1.12 0.957,1.3 171 1699 0.0871 1.15 0.981,1.34 166 1667
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.2679 1.09 0.933,1.28 154 1540 0.2366 1.1 0.938,1.3 151 1509
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.1321 1.1 0.97,1.26 248 2480 0.04898 1.14 1.0,1.3 234 2409
425.8 Other cardiomyopathy circulatory system Both 0.8222 1.03 0.81,1.3 71 709 0.871 1.02 0.797,1.31 67 690
426 Cardiac conduction disorders circulatory system Both 0.3221 0.987 0.962,1.01 9881 21221 0.3606 1.04 0.957,1.13 619 5606
426.2 Atrioventricular [AV] block circulatory system Both 0.6855 1.01 0.957,1.07 1527 9610 1.0 1.0 0.849,1.18 159 1466
426.21 First degree AV block circulatory system Both 0.7464 0.989 0.927,1.06 1064 7510 0.6237 0.984 0.921,1.05 1034 7375
426.22 Mobitz II AV block circulatory system Both 0.8531 0.975 0.743,1.28 56 513 0.8851 0.98 0.748,1.29 56 504
426.23 Second degree AV block circulatory system Both 0.4436 0.938 0.796,1.1 161 1459 0.5093 0.946 0.802,1.12 157 1437
426.24 Atrioventricular block, complete circulatory system Both 0.3404 1.05 0.945,1.18 357 3041 0.3936 1.05 0.94,1.17 350 2996
426.25 Other heart block circulatory system Both 0.8892 1.01 0.86,1.19 161 1489 1.0 1.0 0.849,1.18 159 1466
426.3 Bundle branch block circulatory system Both 0.3048 1.03 0.976,1.08 1775 11373 0.2051 1.05 0.973,1.14 707 6121
426.31 Right bundle branch block circulatory system Both 0.2911 1.03 0.971,1.1 1101 8763 0.4295 1.03 0.963,1.09 1079 8614
426.32 Left bundle branch block circulatory system Both 0.2339 1.05 0.97,1.13 721 6217 0.2051 1.05 0.973,1.14 707 6121
426.4 Anomalous atrioventricular excitation circulatory system Both 0.07413 0.782 0.597,1.02 62 611 0.1567 0.82 0.624,1.08 60 605
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.414 0.989 0.963,1.02 8452 21094 0.3342 0.987 0.961,1.01 8166 20756
426.8 Other cardiac conduction disorders circulatory system Both 0.08128 1.09 0.99,1.2 456 4529 0.1288 1.08 0.978,1.19 445 4453
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.875 0.995 0.937,1.06 1261 8802 0.3606 1.04 0.957,1.13 619 5606
426.91 Cardiac pacemaker in situ circulatory system Both 0.4446 0.972 0.903,1.05 836 6124 0.4198 0.97 0.901,1.04 820 6020
426.92 Cardiac defibrillator in situ circulatory system Both 0.4256 1.03 0.953,1.12 628 5698 0.3606 1.04 0.957,1.13 619 5606
427 Cardiac dysrhythmias circulatory system Both 0.8337 0.998 0.976,1.02 14018 21321 0.8072 1.0 0.968,1.04 3359 19836
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.3926 1.02 0.973,1.07 1882 14769 0.2729 1.04 0.97,1.11 875 7855
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.2296 1.04 0.977,1.1 1193 11216 0.2023 1.04 0.979,1.1 1168 11025
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.2754 1.04 0.97,1.11 892 7975 0.2729 1.04 0.97,1.11 875 7855
427.2 Atrial fibrillation and flutter circulatory system Both 0.2275 1.02 0.986,1.06 4194 15493 0.3404 1.03 0.972,1.08 1566 9506
427.21 Atrial fibrillation circulatory system Both 0.2679 1.02 0.984,1.06 4097 15312 0.2173 1.02 0.986,1.06 4008 15057
427.22 Atrial flutter circulatory system Both 0.3972 1.02 0.97,1.08 1598 9674 0.3404 1.03 0.972,1.08 1566 9506
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.5433 0.991 0.964,1.02 7129 21276 0.3192 0.986 0.958,1.01 6881 20933
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.03311 1.12 1.01,1.23 419 4137 0.01318 1.16 1.03,1.29 315 3142
427.41 Ventricular fibrillation and flutter circulatory system Both 0.2009 1.11 0.947,1.29 167 1670 0.2704 1.09 0.934,1.28 165 1644
427.42 Cardiac arrest circulatory system Both 0.01479 1.15 1.03,1.29 321 3186 0.01318 1.16 1.03,1.29 315 3142
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.5047 1.01 0.98,1.04 5521 21271 0.6668 1.01 0.976,1.04 5288 20928
427.6 Premature beats circulatory system Both 0.7211 0.991 0.943,1.04 1820 13218 0.7295 0.984 0.897,1.08 504 4795
427.61 Supraventricular premature beats circulatory system Both 0.7278 0.984 0.899,1.08 522 4879 0.7295 0.984 0.897,1.08 504 4795
427.7 Tachycardia NOS circulatory system Both 0.7586 1.01 0.972,1.04 3980 21286 0.7178 1.01 0.972,1.04 3829 20943
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.8279 0.992 0.918,1.07 738 6224 0.7943 0.99 0.915,1.07 715 6127
427.9 Palpitations circulatory system Both 0.869 1.0 0.967,1.04 3420 20157 0.8072 1.0 0.968,1.04 3359 19836
428 Congestive heart failure; nonhypertensive circulatory system Both 0.5546 0.989 0.952,1.03 3326 19946 0.9226 0.997 0.938,1.06 1180 10379
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.7145 1.01 0.969,1.05 2965 19130 0.547 1.01 0.973,1.05 2897 18719
428.2 Heart failure NOS circulatory system Both 0.5309 0.987 0.948,1.03 2781 17962 0.7244 0.993 0.953,1.03 2723 17573
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.8913 1.0 0.948,1.06 1288 11396 0.6577 1.01 0.956,1.07 1260 11142
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.7834 0.992 0.934,1.05 1208 10616 0.9226 0.997 0.938,1.06 1180 10379
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.4305 0.99 0.967,1.01 9394 27581 0.4677 0.969 0.889,1.06 577 5699
429.1 Heart transplant/surgery circulatory system Both 0.0631 1.07 0.996,1.15 823 8070 0.04571 1.08 1.0,1.16 805 7894
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.5508 0.99 0.958,1.02 4445 23965 0.6124 0.991 0.959,1.02 4296 23447
429.3 Symptoms involving cardiovascular system circulatory system Both 0.4529 0.99 0.964,1.02 7147 27443 0.492 0.991 0.964,1.02 6920 26864
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.3715 0.962 0.884,1.05 591 5816 0.4677 0.969 0.889,1.06 577 5699
430 Intracranial hemorrhage circulatory system Both 0.5483 1.02 0.946,1.11 633 6305 0.3357 1.08 0.924,1.26 173 1973
430.1 Subarachnoid hemorrhage circulatory system Both 0.7762 1.02 0.896,1.16 230 2300 0.8091 1.02 0.89,1.16 214 2254
430.2 Intracerebral hemorrhage circulatory system Both 0.9705 1.0 0.895,1.12 314 3132 0.3882 0.944 0.829,1.08 231 3070
430.3 Subdural hemorrhage circulatory system Both 0.1476 1.11 0.963,1.29 202 2017 0.3357 1.08 0.924,1.26 173 1973
433 Cerebrovascular disease circulatory system Both 0.07244 0.971 0.939,1.0 4361 26660 0.7745 1.01 0.924,1.11 490 5195
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.877 0.996 0.944,1.05 1533 12978 0.7568 1.04 0.804,1.35 59 591
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.9727 0.997 0.858,1.16 188 1858 0.9204 0.992 0.851,1.16 180 1831
433.12 Cerebral atherosclerosis circulatory system Both 0.9204 1.01 0.784,1.31 61 599 0.7568 1.04 0.804,1.35 59 591
433.2 Occlusion of cerebral arteries circulatory system Both 0.1216 0.963 0.919,1.01 1926 17593 0.114 0.961 0.915,1.01 1783 16691
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.156 0.966 0.921,1.01 1862 17011 0.114 0.961 0.915,1.01 1783 16691
433.3 Cerebral ischemia circulatory system Both 0.2582 0.974 0.931,1.02 2122 18040 0.4385 0.981 0.933,1.03 1746 15762
433.31 Transient cerebral ischemia circulatory system Both 0.6194 0.988 0.941,1.04 1812 16062 0.4385 0.981 0.933,1.03 1746 15762
433.5 Cerebral aneurysm circulatory system Both 0.4645 1.04 0.939,1.15 408 4070 0.5768 1.03 0.929,1.14 395 3987
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.6887 1.02 0.921,1.13 383 3803 0.7638 1.02 0.913,1.13 360 3739
433.8 Late effects of cerebrovascular disease circulatory system Both 0.6982 1.02 0.931,1.11 534 5286 0.7745 1.01 0.924,1.11 490 5195
440 Atherosclerosis circulatory system Both 0.3776 0.979 0.934,1.03 1946 16499 0.1274 0.941 0.87,1.02 693 6615
440.1 Atherosclerosis of renal artery circulatory system Both 0.2958 1.08 0.935,1.25 187 1855 0.2455 1.09 0.942,1.26 182 1803
440.2 Atherosclerosis of the extremities circulatory system Both 0.3873 0.974 0.917,1.03 1166 11265 0.06607 0.935 0.87,1.0 804 7764
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.2636 1.09 0.939,1.26 183 1815 0.263 1.09 0.938,1.26 182 1747
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.05248 0.932 0.867,1.0 812 7979 0.06607 0.935 0.87,1.0 804 7764
440.9 Atherosclerosis of aorta circulatory system Both 0.1076 0.938 0.868,1.01 702 6800 0.1274 0.941 0.87,1.02 693 6615
441 Vascular insufficiency of intestine circulatory system Both 0.7998 1.01 0.916,1.12 407 4039 0.8851 1.01 0.844,1.22 120 1185
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.9977 1.0 0.869,1.15 206 2025 0.9506 1.0 0.872,1.16 204 1982
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.7762 1.03 0.856,1.23 122 1207 0.8851 1.01 0.844,1.22 120 1185
442 Other aneurysm circulatory system Both 0.5834 1.01 0.969,1.06 2309 18098 0.6237 0.972 0.869,1.09 323 3208
442.1 Aortic aneurysm circulatory system Both 0.4753 1.02 0.969,1.07 1703 13812 0.4667 1.02 0.96,1.09 982 8771
442.11 Abdominal aortic aneurysm circulatory system Both 0.5358 1.02 0.956,1.09 992 9021 0.4667 1.02 0.96,1.09 982 8771
442.2 Aneurysm of iliac artery circulatory system Both 0.7079 1.03 0.883,1.2 177 1769 0.7674 1.02 0.876,1.2 171 1730
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.3155 1.09 0.917,1.31 137 1357 0.2612 1.11 0.927,1.32 135 1312
442.4 Arterial dissection circulatory system Both 0.8433 1.02 0.862,1.2 156 1555 0.7345 1.03 0.872,1.21 152 1511
442.8 Aneurysm of other specified artery circulatory system Both 0.5321 0.965 0.863,1.08 330 3300 0.6237 0.972 0.869,1.09 323 3208
443 Peripheral vascular disease circulatory system Both 0.6855 0.991 0.95,1.03 2355 20353 0.857 0.995 0.947,1.05 1719 14756
443.1 Raynaud's syndrome circulatory system Both 0.6368 0.98 0.902,1.07 608 6051 0.7413 0.986 0.907,1.07 600 5900
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.6745 1.04 0.87,1.24 141 1375 0.6592 1.04 0.871,1.24 139 1341
443.8 Other specified peripheral vascular diseases circulatory system Both 0.9204 0.998 0.951,1.05 1899 17476 0.8995 1.0 0.956,1.05 1868 17030
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.6368 0.988 0.94,1.04 1747 15154 0.857 0.995 0.947,1.05 1719 14756
444 Arterial embolism and thrombosis circulatory system Both 0.8035 1.01 0.933,1.09 675 6732 0.2489 1.11 0.93,1.32 128 1247
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.7244 1.02 0.898,1.17 240 2392 0.8995 1.01 0.883,1.15 235 2322
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.2547 1.11 0.929,1.32 129 1282 0.2489 1.11 0.93,1.32 128 1247
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.2529 1.06 0.957,1.18 367 3641 0.5408 1.04 0.911,1.19 226 2228
446.4 Wegener's granulomatosis circulatory system Both 0.09772 1.2 0.967,1.49 86 857 0.08318 1.21 0.975,1.51 84 843
446.5 Giant cell arteritis circulatory system Both 0.2109 1.17 0.914,1.51 59 547 0.1175 1.23 0.95,1.59 54 537
446.9 Arteritis NOS circulatory system Both 0.5188 1.05 0.914,1.19 230 2285 0.5408 1.04 0.911,1.19 226 2228
447 Other disorders of arteries and arterioles circulatory system Both 0.1135 0.964 0.922,1.01 2116 18819 0.6124 1.02 0.941,1.11 623 6169
447.1 Stricture of artery circulatory system Both 0.9931 1.0 0.908,1.1 435 4322 0.8472 1.01 0.916,1.11 425 4219
447.7 Aortic ectasia circulatory system Both 0.5848 1.02 0.944,1.11 637 6315 0.6124 1.02 0.941,1.11 623 6169
448 Disease of capillaries circulatory system Both 0.4395 1.03 0.958,1.1 853 8472 0.4667 1.03 0.956,1.1 837 8282
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.103 1.04 0.992,1.1 1701 17006 0.07413 1.05 0.995,1.1 1639 16614
451 Phlebitis and thrombophlebitis circulatory system Both 0.4276 0.966 0.888,1.05 582 5764 0.2249 0.912 0.787,1.06 184 1836
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.3119 0.928 0.802,1.07 190 1888 0.2249 0.912 0.787,1.06 184 1836
452 Other venous embolism and thrombosis circulatory system Both 0.8035 0.996 0.962,1.03 3773 25068 0.5598 1.06 0.875,1.28 115 1153
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.6934 1.03 0.899,1.17 228 2277 0.6281 1.03 0.903,1.18 222 2225
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.5212 0.987 0.948,1.03 2623 22444 0.4385 0.984 0.944,1.03 2512 21917
452.8 Postphlebitic syndrome circulatory system Both 0.867 1.02 0.842,1.23 119 1181 0.5598 1.06 0.875,1.28 115 1153
453 Chronic venous hypertension circulatory system Both 0.5272 1.05 0.902,1.22 173 1715 0.4305 1.06 0.912,1.24 170 1672
454 Varicose veins circulatory system Both 0.2541 0.975 0.933,1.02 2206 20243 0.5521 0.982 0.924,1.04 1163 11489
454.1 Varicose veins of lower extremity circulatory system Both 0.2163 0.97 0.925,1.02 1908 17574 0.5521 0.982 0.924,1.04 1163 11489
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.6166 0.985 0.928,1.05 1182 11754 0.5521 0.982 0.924,1.04 1163 11489
455 Hemorrhoids circulatory system Both 0.4178 1.01 0.981,1.05 4379 24588 0.3311 1.02 0.984,1.05 4297 24029
456 Chronic venous insufficiency [CVI] circulatory system Both 0.1959 0.972 0.931,1.01 2303 20367 0.2208 0.973 0.931,1.02 2251 19907
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.1276 1.04 0.989,1.09 1946 14131 0.04786 1.05 1.0,1.11 1772 13339
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.9462 0.996 0.882,1.12 287 2845 0.9528 1.0 0.888,1.13 280 2781
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.1265 1.04 0.989,1.09 1841 13661 0.04786 1.05 1.0,1.11 1772 13339
458 Hypotension circulatory system Both 0.8453 1.0 0.971,1.04 4073 28546 0.8279 0.996 0.961,1.03 3485 26873
458.1 Orthostatic hypotension circulatory system Both 0.07943 1.06 0.993,1.13 1031 10176 0.1197 1.05 0.987,1.12 982 9919
458.2 Iatrogenic hypotension circulatory system Both 0.6871 1.01 0.947,1.09 911 9084 0.6546 1.02 0.948,1.09 888 8871
458.9 Hypotension NOS circulatory system Both 0.8318 0.996 0.962,1.03 3641 27465 0.8279 0.996 0.961,1.03 3485 26873
459 Other disorders of circulatory system circulatory system Both 0.6486 1.01 0.973,1.04 3553 27674 0.5808 1.01 0.972,1.05 2682 23139
459.1 Hemorrhage NOS circulatory system Both 0.7311 0.985 0.906,1.07 619 6159 0.7096 0.984 0.904,1.07 600 6021
459.7 Blood vessel replaced circulatory system Both 0.03802 1.16 1.01,1.33 203 2030 0.02884 1.17 1.02,1.34 199 1973
459.9 Circulatory disease NEC circulatory system Both 0.5662 1.01 0.972,1.05 2757 23656 0.5808 1.01 0.972,1.05 2682 23139
464 Acute sinusitis respiratory Both 0.826 0.996 0.962,1.03 3675 26562 0.9204 0.998 0.964,1.03 3596 25925
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.6368 0.994 0.968,1.02 7223 30143 0.2466 1.07 0.956,1.19 341 3358
465.2 Acute pharyngitis respiratory Both 0.1197 0.974 0.941,1.01 3967 26715 0.1476 0.975 0.942,1.01 3892 26080
465.4 Acute laryngitis and tracheitis respiratory Both 0.2228 1.07 0.959,1.19 345 3441 0.2466 1.07 0.956,1.19 341 3358
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.673 0.988 0.936,1.04 1431 14130 0.7638 0.992 0.939,1.05 1404 13793
471 Nasal polyps respiratory Both 0.7295 0.983 0.895,1.08 475 4727 0.861 0.991 0.901,1.09 463 4609
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.208 0.965 0.912,1.02 1344 13251 0.2028 0.964 0.91,1.02 1314 12932
473 Diseases of the larynx and vocal cords respiratory Both 0.9036 0.997 0.956,1.04 2393 20985 0.6918 1.01 0.962,1.06 1818 17611
473.1 Chronic laryngitis respiratory Both 0.6295 1.07 0.817,1.4 57 562 0.975 1.0 0.763,1.32 55 548
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.4592 1.03 0.946,1.13 517 5167 0.3034 1.05 0.957,1.15 485 5048
473.4 Voice disturbance respiratory Both 0.7798 1.01 0.96,1.06 1880 18033 0.6918 1.01 0.962,1.06 1818 17611
474 Acute and chronic tonsillitis respiratory Both 0.1607 0.945 0.873,1.02 685 6193 0.5284 0.972 0.891,1.06 547 5037
474.1 Acute tonsillitis respiratory Both 0.0871 0.895 0.788,1.02 267 2507 0.07586 0.891 0.784,1.01 263 2456
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.471 0.969 0.888,1.06 555 5166 0.5284 0.972 0.891,1.06 547 5037
475 Chronic sinusitis respiratory Both 0.743 0.994 0.959,1.03 3434 23149 0.861 0.993 0.914,1.08 635 6286
475.9 Postnasal drip respiratory Both 0.8551 0.992 0.915,1.08 651 6441 0.861 0.993 0.914,1.08 635 6286
476 Allergic rhinitis respiratory Both 0.4365 0.991 0.968,1.01 10205 23354 0.4797 0.991 0.968,1.02 9974 22815
477 Epistaxis or throat hemorrhage respiratory Both 0.9333 0.997 0.931,1.07 895 8841 0.8913 0.995 0.928,1.07 863 8642
478 Throat pain respiratory Both 0.3192 0.943 0.841,1.06 325 3233 0.2844 0.939 0.836,1.05 319 3149
479 Other upper respiratory disease respiratory Both 0.1807 0.978 0.947,1.01 4428 23338 0.3648 0.985 0.953,1.02 4286 22799
480 Pneumonia respiratory Both 0.7852 1.0 0.974,1.04 4823 30881 0.7015 1.04 0.851,1.27 106 1140
480.1 Bacterial pneumonia respiratory Both 0.5433 1.02 0.953,1.1 860 8567 0.1117 0.819 0.64,1.05 76 794
480.11 Pneumococcal pneumonia respiratory Both 0.6026 1.03 0.925,1.14 372 3720 0.5768 1.03 0.926,1.15 365 3648
480.12 Pseudomonal pneumonia respiratory Both 0.6902 1.04 0.865,1.24 121 1192 0.6152 1.05 0.872,1.26 118 1156
480.13 MRSA pneumonia respiratory Both 0.1416 0.836 0.659,1.06 82 818 0.1117 0.819 0.64,1.05 76 794
480.2 Viral pneumonia respiratory Both 0.7295 1.03 0.872,1.22 147 1461 0.6124 1.04 0.882,1.24 142 1440
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.4581 0.931 0.769,1.13 117 1170 0.4325 0.925 0.762,1.12 113 1147
480.5 Bronchopneumonia and lung abscess respiratory Both 0.7413 1.03 0.854,1.25 119 1175 0.7015 1.04 0.851,1.27 106 1140
481 Influenza respiratory Both 0.3606 0.97 0.908,1.04 990 9863 0.335 0.968 0.906,1.03 975 9660
483 Acute bronchitis and bronchiolitis respiratory Both 0.7129 0.992 0.953,1.03 2615 24227 0.7447 0.993 0.954,1.03 2561 23730
495 Asthma respiratory Both 0.7834 1.0 0.977,1.03 6951 27725 0.8511 1.01 0.948,1.07 1221 12154
495.1 Chronic obstructive asthma respiratory Both 0.4246 1.05 0.937,1.17 341 3403 0.7727 0.962 0.742,1.25 58 582
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.6166 0.937 0.726,1.21 60 592 0.7727 0.962 0.742,1.25 58 582
495.2 Asthma with exacerbation respiratory Both 0.9661 1.0 0.945,1.06 1251 12442 0.8511 1.01 0.948,1.07 1221 12154
496 Chronic airway obstruction respiratory Both 0.4539 0.988 0.956,1.02 4444 23893 0.02951 0.892 0.805,0.989 422 4219
496.1 Emphysema respiratory Both 0.4111 0.98 0.934,1.03 1831 16712 0.4064 0.979 0.932,1.03 1771 16309
496.2 Chronic bronchitis respiratory Both 0.5943 0.99 0.955,1.03 3357 22668 0.4406 0.985 0.948,1.02 2963 21185
496.21 Obstructive chronic bronchitis respiratory Both 0.3811 0.983 0.946,1.02 3040 21701 0.4406 0.985 0.948,1.02 2963 21185
496.3 Bronchiectasis respiratory Both 0.03715 0.898 0.811,0.994 435 4329 0.02951 0.892 0.805,0.989 422 4219
497 Bronchitis respiratory Both 0.2118 0.967 0.916,1.02 1481 14700 0.2559 0.969 0.918,1.02 1459 14365
498 Acute bronchospasm respiratory Both 0.2931 0.944 0.849,1.05 376 3745 0.3556 0.95 0.853,1.06 367 3645
499 Cystic fibrosis respiratory Both 0.778 0.972 0.799,1.18 116 1160 0.9661 0.996 0.816,1.22 113 1135
500 Lung disease due to external agents respiratory Both 0.07943 1.09 0.99,1.2 428 4273 0.1413 1.22 0.937,1.58 61 624
500.1 Extrinsic allergic alveolitis respiratory Both 0.3436 1.11 0.895,1.37 81 810 0.2818 1.13 0.906,1.4 77 792
500.2 Pneumoconiosis respiratory Both 0.2673 1.16 0.895,1.49 65 640 0.1413 1.22 0.937,1.58 61 624
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.4819 1.03 0.944,1.13 514 5078 0.875 1.01 0.918,1.11 480 4975
502 Postinflammatory pulmonary fibrosis respiratory Both 0.6966 1.02 0.937,1.1 623 6192 0.7586 1.01 0.933,1.1 605 6069
503 Pulmonary congestion and hypostasis respiratory Both 0.5023 1.03 0.95,1.11 690 6875 0.5902 1.02 0.944,1.11 669 6721
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.7603 0.985 0.895,1.08 447 4454 0.1923 0.917 0.806,1.04 244 2403
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.1426 0.908 0.797,1.03 247 2456 0.1923 0.917 0.806,1.04 244 2403
505 Other pulmonary inflamation or edema respiratory Both 0.975 0.999 0.945,1.06 1352 13261 0.9419 1.0 0.947,1.06 1313 12999
506 Empyema and pneumothorax respiratory Both 0.7568 1.01 0.966,1.05 2588 22332 0.6607 1.01 0.968,1.05 2490 21868
507 Pleurisy; pleural effusion respiratory Both 0.7834 0.994 0.953,1.04 2415 21828 0.9528 0.999 0.957,1.04 2331 21382
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.5957 0.988 0.943,1.03 2005 19256 0.4315 0.981 0.936,1.03 1917 18874
509 Respiratory failure, insufficiency, arrest respiratory Both 0.3388 0.982 0.945,1.02 3044 23898 0.2812 0.961 0.893,1.03 821 8298
509.1 Respiratory failure respiratory Both 0.526 0.983 0.931,1.04 1466 14560 0.6266 0.986 0.934,1.04 1398 14239
509.2 Respiratory insufficiency respiratory Both 0.7852 0.991 0.925,1.06 928 9238 0.867 0.994 0.927,1.07 890 9031
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.5483 0.984 0.933,1.04 1500 14783 0.5176 0.982 0.931,1.04 1443 14472
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.3311 0.965 0.898,1.04 848 8472 0.2812 0.961 0.893,1.03 821 8298
510 Other diseases of lung respiratory Both 0.2153 1.02 0.989,1.05 4671 30168 0.6194 0.955 0.794,1.15 125 1243
510.2 Lung transplant respiratory Both 0.6982 0.965 0.805,1.16 128 1274 0.6194 0.955 0.794,1.15 125 1243
512 Other symptoms of respiratory system respiratory Both 0.3899 0.991 0.971,1.01 14878 23476 0.7015 0.995 0.97,1.02 8374 23002
512.1 Wheezing respiratory Both 0.7568 0.99 0.93,1.05 1071 10626 0.877 0.995 0.933,1.06 1034 10401
512.2 Painful respiration respiratory Both 0.04898 0.952 0.906,1.0 1765 17029 0.03802 0.948 0.902,0.997 1716 16720
512.3 Abnormal chest sounds respiratory Both 0.2477 0.923 0.807,1.06 229 2261 0.2618 0.925 0.807,1.06 222 2219
512.7 Shortness of breath respiratory Both 0.8241 0.997 0.972,1.02 7928 23452 0.9141 0.999 0.973,1.03 7688 22987
512.8 Cough respiratory Both 0.9311 1.0 0.975,1.03 7280 23469 0.7852 1.0 0.977,1.03 7088 23004
512.9 Other dyspnea respiratory Both 0.7015 0.995 0.971,1.02 8658 23467 0.7015 0.995 0.97,1.02 8374 23002
513 Respiratory abnormalities respiratory Both 0.8974 0.998 0.976,1.02 10231 28110 0.9057 0.991 0.855,1.15 197 2012
513.3 Hypoventilation respiratory Both 0.7816 1.01 0.932,1.1 618 6146 0.865 0.986 0.842,1.16 161 1617
513.31 Apnea respiratory Both 0.9484 1.0 0.894,1.13 314 3136 0.7727 1.02 0.905,1.14 307 3071
513.32 Orthopnea respiratory Both 0.7962 0.98 0.838,1.15 167 1662 0.865 0.986 0.842,1.16 161 1617
513.4 Hyperventilation respiratory Both 0.236 0.942 0.853,1.04 440 4383 0.2799 0.946 0.855,1.05 424 4295
513.8 Disorders of diaphragm respiratory Both 0.9772 1.0 0.867,1.16 206 2053 0.9057 0.991 0.855,1.15 197 2012
514 Abnormal findings examination of lungs respiratory Both 0.00955 1.04 1.01,1.08 4486 29229 3.981E-5 1.09 1.05,1.14 2373 22205
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.3027 0.925 0.799,1.07 193 1914 0.2999 0.924 0.795,1.07 187 1867
514.2 Solitary pulmonary nodule respiratory Both 8.71E-5 1.09 1.04,1.13 2489 22668 3.981E-5 1.09 1.05,1.14 2373 22205
516 Abnormal sputum respiratory Both 0.3945 1.04 0.952,1.13 565 5640 0.1191 1.08 0.98,1.19 453 4603
516.1 Hemoptysis respiratory Both 0.1271 1.08 0.979,1.18 473 4720 0.1191 1.08 0.98,1.19 453 4603
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.4169 1.01 0.983,1.04 5153 32053 0.1578 1.02 0.991,1.06 3888 28538
519.1 Tracheostomy complications respiratory Both 0.3508 1.08 0.922,1.26 176 1760 0.4159 1.07 0.912,1.25 168 1718
519.2 Respiratory complications respiratory Both 0.05248 0.9 0.81,1.0 370 3696 0.06761 0.905 0.813,1.01 364 3601
519.8 Other diseases of respiratory system, NEC respiratory Both 0.6353 1.02 0.949,1.09 887 8857 0.52 1.02 0.955,1.1 867 8659
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.1968 1.02 0.989,1.06 4043 29199 0.1578 1.02 0.991,1.06 3888 28538
520 Disorders of tooth development digestive Both 0.1972 1.08 0.96,1.22 291 2900 0.3707 1.07 0.918,1.26 169 1657
520.1 Hereditary disturbances in tooth structure digestive Both 0.4819 1.06 0.894,1.27 131 1301 0.514 1.06 0.889,1.26 129 1276
520.2 Disturbances in tooth eruption digestive Both 0.4634 1.06 0.906,1.24 172 1693 0.3707 1.07 0.918,1.26 169 1657
521 Diseases of hard tissues of teeth digestive Both 0.4808 1.03 0.952,1.11 719 7167 0.5675 1.02 0.945,1.11 651 6537
521.1 Dental caries digestive Both 0.7745 1.01 0.935,1.09 673 6709 0.5675 1.02 0.945,1.11 651 6537
522 Diseases of pulp and periapical tissues digestive Both 0.4385 1.04 0.94,1.15 408 4067 0.6934 1.02 0.913,1.15 332 3301
522.5 Periapical abscess digestive Both 0.6808 1.02 0.916,1.14 341 3404 0.6934 1.02 0.913,1.15 332 3301
523 Gingival and periodontal diseases digestive Both 0.4074 0.965 0.886,1.05 569 5690 0.9817 1.0 0.818,1.23 99 998
523.1 Gingivitis digestive Both 0.03548 0.818 0.678,0.986 117 1163 0.05129 0.828 0.685,1.0 112 1142
523.3 Periodontitis (acute or chronic) digestive Both 0.3758 1.06 0.937,1.19 294 2940 0.9817 1.0 0.818,1.23 99 998
523.31 Acute periodontitis digestive Both 0.1038 1.11 0.979,1.26 251 2510 0.1507 1.1 0.966,1.25 241 2441
523.32 Chronic periodontitis digestive Both 0.7834 1.03 0.842,1.26 103 1030 0.9817 1.0 0.818,1.23 99 998
524 Dentofacial anomalies, including malocclusion digestive Both 0.2877 0.939 0.836,1.05 308 3080 0.2432 0.915 0.787,1.06 185 1816
524.3 Anomalies of tooth position/malocclusion digestive Both 0.2244 0.911 0.785,1.06 186 1856 0.2432 0.915 0.787,1.06 185 1816
525 Other diseases of the teeth and supporting structures digestive Both 0.4688 0.974 0.908,1.05 853 8530 0.7295 0.98 0.873,1.1 312 3100
525.1 Loss of teeth or edentulism digestive Both 0.826 0.987 0.88,1.11 318 3178 0.7295 0.98 0.873,1.1 312 3100
526 Diseases of the jaws digestive Both 0.6653 0.99 0.947,1.04 2140 21162 0.2183 0.937 0.844,1.04 391 3891
526.1 Cysts of the jaws digestive Both 0.5649 0.959 0.832,1.11 213 2123 0.695 0.972 0.843,1.12 211 2071
526.3 Anomalies of jaw size/symmetry digestive Both 0.5861 0.962 0.836,1.11 206 2052 0.6039 0.964 0.837,1.11 205 2002
526.4 Temporomandibular joint disorders digestive Both 0.8995 0.996 0.938,1.06 1178 11779 0.3864 1.04 0.954,1.13 592 5852
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.673 0.986 0.922,1.05 941 9410 0.7674 0.99 0.925,1.06 929 9201
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.3899 1.04 0.954,1.13 600 5993 0.3864 1.04 0.954,1.13 592 5852
526.5 Inflammatory conditions of jaw digestive Both 0.1675 0.912 0.8,1.04 242 2405 0.1963 0.917 0.804,1.05 238 2343
526.9 Jaw disease NOS digestive Both 0.2339 0.939 0.847,1.04 399 3982 0.2183 0.937 0.844,1.04 391 3891
527 Diseases of the salivary glands digestive Both 0.6067 1.01 0.96,1.07 1362 13604 0.236 1.09 0.943,1.27 185 1921
527.2 Sialoadenitis digestive Both 0.9204 1.01 0.896,1.13 320 3200 0.8974 1.01 0.897,1.13 315 3124
527.7 Disturbance of salivary secretion digestive Both 0.8375 0.992 0.919,1.07 715 7141 0.857 0.993 0.918,1.07 686 6980
527.8 Other specified diseases of the salivary glands digestive Both 0.1596 1.11 0.96,1.28 196 1960 0.236 1.09 0.943,1.27 185 1921
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.2004 1.03 0.984,1.08 2077 20750 0.7413 0.969 0.806,1.17 132 1286
528.1 Stomatitis and mucositis digestive Both 0.03467 1.1 1.01,1.2 536 5360 0.4285 1.07 0.909,1.25 165 1668
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.6871 0.967 0.821,1.14 165 1650 0.7656 0.975 0.826,1.15 160 1619
528.12 Oral aphthae digestive Both 0.2427 1.1 0.938,1.29 170 1700 0.4285 1.07 0.909,1.25 165 1668
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.7834 1.02 0.879,1.19 185 1837 0.7638 1.02 0.879,1.19 179 1799
528.4 Cysts of oral soft tissues digestive Both 0.5861 0.946 0.775,1.16 110 1096 0.5702 0.931 0.727,1.19 67 656
528.41 Cyst of the salivary gland digestive Both 0.561 0.93 0.728,1.19 68 679 0.5702 0.931 0.727,1.19 67 656
528.5 Diseases of lips digestive Both 0.4236 1.05 0.936,1.17 334 3340 0.6427 1.03 0.918,1.15 328 3253
528.6 Leukoplakia of oral mucosa digestive Both 0.1374 1.15 0.956,1.39 113 1120 0.1045 1.17 0.968,1.41 112 1095
528.7 Sialolithiasis digestive Both 0.6592 0.959 0.798,1.15 132 1320 0.7413 0.969 0.806,1.17 132 1286
529 Diseases and other conditions of the tongue digestive Both 0.6252 1.02 0.936,1.12 541 5402 0.2094 1.12 0.936,1.35 134 1324
529.1 Glossitis digestive Both 0.5675 1.06 0.868,1.29 99 982 0.7194 1.04 0.847,1.27 94 959
529.6 Glossodynia digestive Both 0.2099 1.12 0.937,1.35 136 1355 0.2094 1.12 0.936,1.35 134 1324
530 Diseases of esophagus digestive Both 0.05888 0.979 0.959,1.0 13874 23034 0.03715 0.938 0.883,0.996 1172 11703
530.1 Esophagitis, GERD and related diseases digestive Both 0.07079 0.98 0.959,1.0 13419 23031 0.5176 0.944 0.794,1.12 142 1407
530.11 GERD digestive Both 0.09772 0.982 0.96,1.0 13059 23031 0.1225 0.983 0.961,1.0 12722 22549
530.12 Ulcer of esophagus digestive Both 0.877 0.991 0.878,1.12 298 2973 0.8995 0.992 0.879,1.12 294 2916
530.13 Barrett's esophagus digestive Both 0.9817 0.999 0.919,1.09 609 6080 0.8433 1.01 0.927,1.1 594 5929
530.14 Reflux esophagitis digestive Both 0.0389 0.945 0.895,0.997 1483 14213 0.07079 0.951 0.901,1.0 1459 13907
530.15 Eosinophilic esophagitis digestive Both 0.4753 0.939 0.791,1.12 145 1441 0.5176 0.944 0.794,1.12 142 1407
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.7907 0.987 0.898,1.09 475 4742 0.7816 0.987 0.897,1.09 466 4643
530.3 Stricture and stenosis of esophagus digestive Both 0.4634 0.972 0.902,1.05 752 7474 0.4406 0.97 0.899,1.05 734 7307
530.5 Disorders of esophageal motility digestive Both 0.2 1.07 0.967,1.17 434 4326 0.2032 1.07 0.966,1.18 431 4246
530.6 Diverticulum of esophagus, acquired digestive Both 0.9817 1.0 0.837,1.2 121 1181 0.8185 1.02 0.851,1.23 118 1156
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.9333 0.989 0.77,1.27 70 700 0.6902 0.948 0.731,1.23 65 681
530.9 Heartburn digestive Both 0.07079 0.947 0.892,1.0 1198 11946 0.03715 0.938 0.883,0.996 1172 11703
531 Peptic ulcer (excl. esophageal) digestive Both 0.4477 0.98 0.931,1.03 1608 16066 0.1603 0.873 0.722,1.06 113 1116
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.4842 0.96 0.856,1.08 311 3103 0.4842 0.959 0.854,1.08 302 3038
531.2 Gastric ulcer digestive Both 0.3945 1.03 0.962,1.1 884 8834 0.4677 1.03 0.957,1.1 860 8623
531.3 Duodenal ulcer digestive Both 0.6501 0.975 0.875,1.09 362 3613 0.5984 0.971 0.87,1.08 352 3530
531.4 Peptic ulcer, site unspecified digestive Both 0.5012 0.972 0.895,1.06 632 6313 0.4217 0.966 0.889,1.05 620 6167
531.5 Gastrojejunal ulcer digestive Both 0.2564 0.897 0.744,1.08 115 1143 0.1603 0.873 0.722,1.06 113 1116
532 Dysphagia digestive Both 0.1734 0.978 0.946,1.01 4457 22190 0.3062 0.983 0.951,1.02 4288 21725
535 Gastritis and duodenitis digestive Both 0.7603 0.993 0.95,1.04 2129 21208 0.9638 1.0 0.938,1.07 969 9590
535.1 Acute gastritis digestive Both 0.09772 1.06 0.989,1.14 814 8139 0.1213 1.06 0.985,1.14 791 7944
535.2 Atrophic gastritis digestive Both 0.7096 1.02 0.903,1.16 250 2500 0.6412 1.03 0.907,1.17 243 2447
535.6 Duodenitis digestive Both 0.3981 0.947 0.834,1.07 265 2650 0.4416 0.951 0.836,1.08 257 2572
535.8 Other specified gastritis digestive Both 0.7047 1.02 0.929,1.11 497 4964 0.7345 1.02 0.927,1.11 487 4842
535.9 Gastritis and duodenitis, NOS digestive Both 0.9099 0.996 0.933,1.06 985 9835 0.9638 1.0 0.938,1.07 969 9590
536 Disorders of function of stomach digestive Both 0.9311 1.0 0.96,1.05 2251 22311 0.881 1.0 0.954,1.06 1665 16441
536.3 Gastroparesis digestive Both 0.6592 1.02 0.931,1.12 489 4876 0.6887 1.02 0.928,1.12 477 4758
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.6561 0.975 0.871,1.09 334 3331 0.8279 0.987 0.881,1.11 323 3257
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 1.0 1.0 0.951,1.05 1699 16834 0.881 1.0 0.954,1.06 1665 16441
537 Other disorders of stomach and duodenum digestive Both 0.6138 0.989 0.948,1.03 2357 23199 0.2163 0.892 0.744,1.07 124 1253
537.1 Lesions of stomach and duodenum digestive Both 0.3006 0.91 0.762,1.09 128 1271 0.2163 0.892 0.744,1.07 124 1253
539 Bariatric surgery digestive Both 0.5984 0.984 0.925,1.05 1118 11180 0.4426 0.976 0.918,1.04 1096 10921
540 Appendiceal conditions digestive Both 0.787 0.986 0.889,1.09 399 3990 0.4256 1.05 0.932,1.18 289 2861
540.1 Appendicitis digestive Both 0.861 0.99 0.887,1.11 349 3490 0.4256 1.05 0.932,1.18 289 2861
540.11 Acute appendicitis digestive Both 0.4634 1.05 0.928,1.18 293 2930 0.4256 1.05 0.932,1.18 289 2861
550 Abdominal hernia digestive Both 0.04571 0.971 0.943,0.999 5517 31191 0.6095 0.984 0.924,1.05 1079 10715
550.1 Inguinal hernia digestive Both 0.7499 0.991 0.939,1.05 1427 13556 0.7852 0.992 0.94,1.05 1411 13206
550.2 Diaphragmatic hernia digestive Both 0.06026 0.959 0.919,1.0 2290 21266 0.04074 0.955 0.914,0.998 2240 20749
550.3 Femoral hernia digestive Both 0.9954 1.0 0.827,1.21 109 1082 0.9683 1.0 0.829,1.22 108 1054
550.4 Umbilical hernia digestive Both 0.1932 0.959 0.9,1.02 1053 10514 0.2296 0.962 0.902,1.03 1033 10231
550.5 Ventral hernia digestive Both 0.2153 0.97 0.924,1.02 1826 18190 0.1849 0.968 0.921,1.02 1789 17716
550.6 Incisional hernia digestive Both 0.7079 0.988 0.929,1.05 1101 10999 0.6095 0.984 0.924,1.05 1079 10715
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.7727 1.01 0.952,1.07 1275 12527 0.3846 1.04 0.947,1.15 432 4286
555.1 Regional enteritis digestive Both 0.4603 0.972 0.902,1.05 775 7701 0.3908 0.967 0.897,1.04 761 7536
555.2 Ulcerative colitis digestive Both 0.07762 1.07 0.993,1.15 768 7591 0.3846 1.04 0.947,1.15 432 4286
555.21 Ulcerative colitis (chronic) digestive Both 0.4786 1.04 0.94,1.14 438 4361 0.3846 1.04 0.947,1.15 432 4286
556 Ulceration of the lower GI tract digestive Both 0.6839 0.98 0.891,1.08 473 4719 0.1496 1.13 0.956,1.34 152 1461
556.1 Ulceration of intestine digestive Both 0.865 0.991 0.895,1.1 412 4099 0.1496 1.13 0.956,1.34 152 1461
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.1824 1.12 0.948,1.33 152 1496 0.1496 1.13 0.956,1.34 152 1461
557 Intestinal malabsorption (non-celiac) digestive Both 0.865 1.0 0.95,1.06 1306 12565 0.4477 1.05 0.931,1.18 300 2985
557.1 Celiac disease digestive Both 0.4989 1.04 0.926,1.17 305 3050 0.4477 1.05 0.931,1.18 300 2985
558 Noninfectious gastroenteritis digestive Both 0.3357 0.98 0.942,1.02 2706 20417 0.4457 0.984 0.945,1.03 2653 20001
559 Ileostomy status digestive Both 0.7834 0.99 0.919,1.07 773 7702 0.8017 0.991 0.92,1.07 766 7548
560 Intestinal obstruction without mention of hernia digestive Both 0.2094 0.974 0.934,1.01 2580 20303 0.3334 0.974 0.923,1.03 1458 14078
560.1 Paralytic ileus digestive Both 0.1972 0.965 0.913,1.02 1429 13524 0.228 0.967 0.914,1.02 1396 13248
560.2 Impaction of intestine digestive Both 0.7727 0.981 0.86,1.12 257 2499 0.6383 0.969 0.848,1.11 250 2440
560.3 Peritoneal or intestinal adhesions digestive Both 0.743 0.979 0.862,1.11 261 2599 0.6546 0.971 0.854,1.1 258 2553
560.4 Other intestinal obstruction digestive Both 0.4764 0.981 0.93,1.03 1489 14381 0.3334 0.974 0.923,1.03 1458 14078
561 Symptoms involving digestive system digestive Both 0.8222 0.997 0.971,1.02 7750 22039 0.857 0.996 0.954,1.04 2310 18611
561.1 Diarrhea digestive Both 0.6855 0.994 0.966,1.02 5986 22042 0.5998 0.992 0.963,1.02 5812 21595
561.2 Flatulence digestive Both 0.9057 0.997 0.956,1.04 2358 18995 0.857 0.996 0.954,1.04 2310 18611
562 Diverticulosis and diverticulitis digestive Both 0.1148 0.974 0.944,1.01 5014 18500 0.5623 1.02 0.96,1.08 1258 11985
562.1 Diverticulosis digestive Both 0.1239 0.975 0.944,1.01 4973 18448 0.1014 0.973 0.942,1.01 4860 18071
562.2 Diverticulitis digestive Both 0.6053 1.02 0.959,1.07 1292 12242 0.5623 1.02 0.96,1.08 1258 11985
563 Constipation digestive Both 0.7709 0.996 0.967,1.03 5639 22004 0.6368 0.993 0.963,1.02 5398 21557
564 Functional digestive disorders digestive Both 0.778 0.996 0.972,1.02 9553 22037 0.6457 0.988 0.94,1.04 1735 16193
564.1 Irritable Bowel Syndrome digestive Both 0.3648 0.981 0.942,1.02 2751 17147 0.4477 0.984 0.945,1.03 2711 16801
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.875 0.997 0.954,1.04 2348 18710 0.871 0.996 0.954,1.04 2288 18316
564.9 Personal history of diseases of digestive system digestive Both 0.6095 0.987 0.94,1.04 1762 16521 0.6457 0.988 0.94,1.04 1735 16193
565 Anal and rectal conditions digestive Both 0.9247 0.998 0.958,1.04 2533 24500 0.7962 1.01 0.943,1.08 913 9067
565.1 Anal and rectal polyp digestive Both 0.9226 1.0 0.939,1.07 932 9300 0.7962 1.01 0.943,1.08 913 9067
567 Peritonitis and retroperitoneal infections digestive Both 0.3614 0.972 0.915,1.03 1149 11482 0.3251 0.97 0.912,1.03 1127 11188
568 Other disorders of peritoneum digestive Both 0.3076 1.03 0.975,1.09 1452 14494 0.1549 1.05 0.983,1.11 1064 10476
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.1409 1.05 0.985,1.12 1076 10752 0.1549 1.05 0.983,1.11 1064 10476
569 Other disorders of intestine digestive Both 0.3622 0.987 0.961,1.01 6343 29512 0.2198 0.963 0.907,1.02 1171 11766
569.1 Toxic gastroenteritis and colitis digestive Both 0.3459 0.939 0.825,1.07 251 2510 0.5 0.954 0.834,1.09 230 2453
569.2 Gastrointestinal complications digestive Both 0.2028 0.962 0.907,1.02 1206 12058 0.2198 0.963 0.907,1.02 1171 11766
571 Chronic liver disease and cirrhosis digestive Both 0.8241 0.996 0.962,1.03 3603 27394 0.7962 1.01 0.919,1.12 431 4307
571.5 Other chronic nonalcoholic liver disease digestive Both 0.8222 1.0 0.969,1.04 3388 27100 0.1035 0.94 0.872,1.01 769 7624
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.1242 0.944 0.876,1.02 781 7802 0.1035 0.94 0.872,1.01 769 7624
571.6 Primary biliary cirrhosis digestive Both 0.5636 0.952 0.804,1.13 146 1460 0.5546 0.95 0.8,1.13 141 1431
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.8241 0.992 0.92,1.07 749 7472 0.7962 1.01 0.919,1.12 431 4307
571.81 Portal hypertension digestive Both 0.5902 1.03 0.932,1.13 441 4400 0.7962 1.01 0.919,1.12 431 4307
572 Ascites (non malignant) digestive Both 0.8241 0.995 0.949,1.04 1884 18805 0.6808 0.99 0.944,1.04 1847 18400
573 Other disorders of liver digestive Both 0.3581 1.01 0.983,1.05 4460 28151 0.4295 0.985 0.95,1.02 3223 27443
573.1 Chronic passive congestion of liver digestive Both 0.1459 0.86 0.701,1.05 100 991 0.1521 0.861 0.702,1.06 99 967
573.2 Liver replaced by transplant digestive Both 0.7261 1.02 0.893,1.18 227 2268 0.7194 1.03 0.893,1.18 222 2217
573.3 Hepatomegaly digestive Both 0.5821 0.969 0.867,1.08 337 3368 0.618 0.972 0.869,1.09 332 3313
573.4 Acute and subacute necrosis of liver digestive Both 0.9931 1.0 0.879,1.14 258 2580 0.9484 1.0 0.881,1.14 251 2521
573.5 Jaundice (not of newborn) digestive Both 0.8375 1.01 0.936,1.09 758 7555 0.7311 1.01 0.94,1.09 742 7403
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.7379 0.992 0.947,1.04 1973 19683 0.6368 0.989 0.943,1.04 1894 19245
573.7 Abnormal results of function study of liver digestive Both 0.8531 1.0 0.96,1.05 2110 21014 0.9772 1.0 0.956,1.05 2051 20556
573.9 Abnormal serum enzyme levels digestive Both 0.3908 0.984 0.95,1.02 3345 28043 0.4295 0.985 0.95,1.02 3223 27443
574 Cholelithiasis and cholecystitis digestive Both 0.7551 1.01 0.967,1.05 2610 25589 0.1897 0.948 0.875,1.03 651 6495
574.1 Cholelithiasis digestive Both 0.8147 0.995 0.954,1.04 2391 23829 0.5152 0.968 0.878,1.07 438 4333
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.9506 1.0 0.884,1.14 260 2580 0.7499 1.02 0.897,1.16 252 2525
574.12 Cholelithiasis with other cholecystitis digestive Both 0.4406 0.962 0.873,1.06 444 4434 0.5152 0.968 0.878,1.07 438 4333
574.2 Calculus of bile duct digestive Both 0.975 1.0 0.927,1.08 696 6939 0.8872 1.01 0.93,1.09 681 6765
574.3 Cholecystitis without cholelithiasis digestive Both 0.2032 0.95 0.877,1.03 667 6662 0.1897 0.948 0.875,1.03 651 6495
575 Other biliary tract disease digestive Both 0.4688 0.983 0.937,1.03 1868 18668 0.6339 0.964 0.83,1.12 184 1838
575.1 Cholangitis digestive Both 0.4753 1.04 0.928,1.17 310 3089 0.4217 1.05 0.933,1.18 302 3014
575.2 Obstruction of bile duct digestive Both 0.542 0.973 0.89,1.06 530 5291 0.5943 0.976 0.892,1.07 517 5158
575.6 Cholesterolosis of gallbladder digestive Both 0.5297 0.952 0.817,1.11 168 1680 0.4898 0.947 0.812,1.1 167 1637
575.7 Other disorders of gallbladder digestive Both 0.9419 0.997 0.927,1.07 773 7719 0.9057 0.996 0.924,1.07 754 7535
575.8 Other disorders of biliary tract digestive Both 0.3784 0.971 0.91,1.04 996 9950 0.3707 0.97 0.908,1.04 974 9708
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.6237 0.964 0.831,1.12 188 1880 0.6339 0.964 0.83,1.12 184 1838
577 Diseases of pancreas digestive Both 0.2371 0.971 0.926,1.02 1842 18379 0.8017 0.988 0.895,1.09 449 4450
577.1 Acute pancreatitis digestive Both 0.5521 0.98 0.917,1.05 967 9651 0.5929 0.982 0.918,1.05 953 9405
577.2 Chronic pancreatitis digestive Both 0.9772 0.998 0.901,1.11 396 3955 0.9616 0.997 0.899,1.11 389 3860
577.3 Cyst and pseudocyst of pancreas digestive Both 0.9204 0.995 0.903,1.1 462 4557 0.8017 0.988 0.895,1.09 449 4450
578 Gastrointestinal hemorrhage digestive Both 0.5521 0.99 0.956,1.02 3572 30460 0.235 0.965 0.909,1.02 1206 11971
578.1 Hematemesis digestive Both 0.6397 1.03 0.923,1.14 383 3821 0.9057 1.01 0.905,1.12 371 3747
578.2 Blood in stool digestive Both 0.7311 0.992 0.949,1.04 2156 21196 0.7907 0.994 0.95,1.04 2097 20675
578.8 Hemorrhage of rectum and anus digestive Both 0.3304 0.976 0.928,1.03 1718 17070 0.3681 0.977 0.929,1.03 1675 16669
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.2382 0.965 0.91,1.02 1238 12280 0.235 0.965 0.909,1.02 1206 11971
579 Other symptoms involving abdomen and pelvis digestive Both 0.6998 0.993 0.96,1.03 3750 28690 0.7925 0.991 0.928,1.06 966 9633
579.2 Splenomegaly digestive Both 0.863 1.01 0.927,1.09 593 5923 0.8511 1.01 0.927,1.1 577 5788
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.8851 0.995 0.932,1.06 998 9882 0.7925 0.991 0.928,1.06 966 9633
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.9099 0.997 0.941,1.06 1264 12626 0.2506 0.928 0.818,1.05 268 2686
580.1 Glomerulonephritis genitourinary Both 0.6081 0.971 0.867,1.09 324 3228 0.4634 0.95 0.827,1.09 225 2244
580.11 Proliferative glomerulonephritis genitourinary Both 0.2388 1.12 0.926,1.36 114 1140 0.2118 1.13 0.932,1.38 111 1113
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.7295 1.04 0.843,1.28 92 905 0.7194 1.04 0.844,1.28 90 880
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.5662 0.961 0.839,1.1 232 2298 0.4634 0.95 0.827,1.09 225 2244
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.02291 1.2 1.03,1.4 167 1670 0.01122 1.22 1.05,1.43 165 1624
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.7603 1.01 0.945,1.08 943 9430 0.455 0.965 0.88,1.06 487 4849
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.2065 1.06 0.97,1.15 554 5535 0.1837 1.06 0.972,1.16 549 5392
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.2917 0.952 0.869,1.04 500 4995 0.455 0.965 0.88,1.06 487 4849
580.4 Renal sclerosis, NOS genitourinary Both 0.1986 0.922 0.814,1.04 275 2750 0.2506 0.928 0.818,1.05 268 2686
585 Renal failure genitourinary Both 0.867 0.998 0.969,1.03 5756 27307 0.02344 0.921 0.857,0.989 833 8174
585.1 Acute renal failure genitourinary Both 0.6998 0.993 0.957,1.03 3278 22851 0.5675 0.989 0.953,1.03 3181 22310
585.2 Renal failure NOS genitourinary Both 0.8054 1.01 0.934,1.09 688 6872 0.8551 1.01 0.93,1.09 671 6689
585.3 Chronic renal failure [CKD] genitourinary Both 0.9638 0.999 0.967,1.03 4216 24655 0.3936 1.03 0.957,1.12 693 6859
585.31 Renal dialysis genitourinary Both 0.7079 0.983 0.901,1.07 543 5430 0.861 0.992 0.908,1.08 531 5296
585.32 End stage renal disease genitourinary Both 0.7816 1.01 0.939,1.09 773 7730 0.7194 1.01 0.941,1.09 757 7547
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.2286 0.973 0.931,1.02 2272 17155 0.3365 0.978 0.936,1.02 2218 16736
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.3917 1.03 0.957,1.12 707 7038 0.3936 1.03 0.957,1.12 693 6859
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.01622 0.917 0.854,0.984 851 8381 0.02344 0.921 0.857,0.989 833 8174
586 Other disorders of the kidney and ureters genitourinary Both 0.2421 1.02 0.989,1.05 6202 28774 0.6427 0.987 0.936,1.04 1507 14326
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.1216 0.908 0.804,1.03 284 2825 0.0631 0.831 0.683,1.01 110 1102
586.11 Small kidney genitourinary Both 0.3289 0.924 0.788,1.08 165 1642 0.3199 0.92 0.782,1.08 158 1609
586.12 Vesicoureteral reflux genitourinary Both 0.06918 0.835 0.688,1.01 112 1120 0.0631 0.831 0.683,1.01 110 1102
586.2 Cyst of kidney, acquired genitourinary Both 0.618 1.02 0.956,1.08 1170 11069 0.618 1.02 0.955,1.08 1125 10809
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.0302 0.833 0.706,0.983 148 1470 0.02951 0.83 0.701,0.982 144 1426
586.4 Stricture/obstruction of ureter genitourinary Both 0.5984 0.986 0.935,1.04 1536 14675 0.6427 0.987 0.936,1.04 1507 14326
587 Kidney replaced by transpant genitourinary Both 0.5012 1.03 0.947,1.12 612 6120 0.3475 1.04 0.957,1.13 599 5969
588 Disorders resulting from impaired renal function genitourinary Both 0.7211 0.986 0.913,1.07 701 7004 0.7112 0.983 0.898,1.08 510 5108
588.1 Renal osteodystrophy genitourinary Both 0.8017 1.02 0.887,1.17 227 2267 0.7482 1.02 0.89,1.18 223 2222
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.6442 0.979 0.895,1.07 525 5241 0.7112 0.983 0.898,1.08 510 5108
589 Abnormal results of function study of kidney genitourinary Both 0.6295 1.02 0.948,1.09 840 8370 0.4955 1.03 0.954,1.1 817 8154
590 Pyelonephritis genitourinary Both 0.5741 1.02 0.958,1.08 1161 11597 0.5998 1.02 0.956,1.08 1138 11347
591 Urinary tract infection genitourinary Both 0.3767 0.989 0.964,1.01 8020 27291 0.375 0.988 0.963,1.01 7784 26692
592 Cystitis and urethritis genitourinary Both 0.7079 1.01 0.965,1.05 2264 19423 0.2286 0.9 0.759,1.07 142 1391
592.1 Cystitis genitourinary Both 0.5272 1.01 0.97,1.06 2149 18531 0.4764 0.961 0.862,1.07 346 3464
592.11 Acute cystitis genitourinary Both 0.9204 1.0 0.946,1.06 1256 12111 0.8511 1.01 0.948,1.07 1218 11841
592.12 Chronic cystitis genitourinary Both 0.9419 0.995 0.857,1.15 199 1972 0.871 1.01 0.871,1.18 194 1927
592.13 Chronic interstitial cystitis genitourinary Both 0.2812 0.943 0.847,1.05 354 3540 0.4764 0.961 0.862,1.07 346 3464
592.2 Urethritis and urethral syndrome genitourinary Both 0.1932 0.893 0.752,1.06 143 1430 0.2286 0.9 0.759,1.07 142 1391
593 Hematuria genitourinary Both 0.1832 0.977 0.944,1.01 3848 26566 0.8453 1.01 0.933,1.09 712 7063
593.1 Gross hematuria genitourinary Both 0.9638 1.0 0.944,1.06 1201 11351 0.9572 1.0 0.944,1.06 1168 11091
593.2 Microscopic hematuria genitourinary Both 0.859 0.993 0.92,1.07 724 7225 0.8453 1.01 0.933,1.09 712 7063
594 Urinary calculus genitourinary Both 0.4325 0.989 0.961,1.02 5516 31876 0.9057 1.01 0.892,1.14 281 2790
594.1 Calculus of kidney genitourinary Both 0.4207 0.988 0.959,1.02 5155 31730 0.4169 0.988 0.959,1.02 5038 30967
594.2 Calculus of lower urinary tract genitourinary Both 0.5152 0.961 0.853,1.08 310 3068 0.5957 0.968 0.858,1.09 302 2986
594.3 Calculus of ureter genitourinary Both 0.5957 0.983 0.924,1.05 1104 11000 0.6699 0.986 0.927,1.05 1081 10721
594.8 Renal colic genitourinary Both 0.9247 1.01 0.892,1.13 286 2851 0.9057 1.01 0.892,1.14 281 2790
595 Hydronephrosis genitourinary Both 0.8166 0.994 0.941,1.05 1410 14092 0.8892 0.996 0.943,1.05 1387 13743
596 Other disorders of bladder genitourinary Both 0.5675 0.988 0.948,1.03 2527 23338 0.5284 0.982 0.928,1.04 1326 13281
596.1 Bladder neck obstruction genitourinary Both 0.09333 0.908 0.811,1.02 333 3288 0.1104 0.911 0.813,1.02 326 3202
596.5 Functional disorders of bladder genitourinary Both 0.4246 0.977 0.924,1.03 1368 13608 0.5284 0.982 0.928,1.04 1326 13281
597 Other disorders of urethra and urinary tract genitourinary Both 0.7551 0.99 0.929,1.06 1041 10322 0.3388 1.08 0.922,1.27 155 1533
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.5957 0.978 0.9,1.06 608 6024 0.6383 0.98 0.901,1.07 598 5880
597.2 Urinary complications NEC genitourinary Both 0.6761 1.01 0.947,1.09 861 8600 0.7413 1.01 0.943,1.09 846 8398
597.8 Urethral hypermobility/ISD genitourinary Both 0.3581 1.08 0.92,1.26 158 1578 0.3388 1.08 0.922,1.27 155 1533
598 Abnormal findings on examination of urine genitourinary Both 0.25 0.966 0.912,1.02 1263 12596 0.2559 0.966 0.91,1.03 1202 12029
598.4 Other cells and casts in urine genitourinary Both 0.9638 1.0 0.809,1.25 91 906 0.9016 1.01 0.814,1.26 89 885
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.1706 0.959 0.904,1.02 1234 12317 0.2559 0.966 0.91,1.03 1202 12029
599 Other symptoms/disorders or the urinary system genitourinary Both 0.6607 0.995 0.973,1.02 11346 25364 0.2773 1.02 0.981,1.07 2292 19802
599.1 Urinary obstruction genitourinary Both 0.8318 0.991 0.91,1.08 580 5634 0.8166 0.99 0.908,1.08 565 5491
599.2 Retention of urine genitourinary Both 0.414 0.986 0.954,1.02 4234 24058 0.4121 0.986 0.953,1.02 4104 23477
599.3 Dysuria genitourinary Both 0.4477 1.01 0.978,1.05 3426 23180 0.2723 1.02 0.984,1.06 3357 22637
599.4 Urinary incontinence genitourinary Both 0.3581 0.985 0.954,1.02 4566 22567 0.3556 0.985 0.953,1.02 4469 22032
599.5 Frequency of urination and polyuria genitourinary Both 0.9931 1.0 0.968,1.03 4277 23742 0.8954 1.0 0.969,1.04 4165 23176
599.6 Oliguria and anuria genitourinary Both 0.9141 0.995 0.91,1.09 513 5104 0.8279 0.99 0.903,1.08 491 4970
599.7 Urethral discharge genitourinary Both 0.1941 0.859 0.683,1.08 83 830 0.3069 0.887 0.704,1.12 82 816
599.8 Other symptoms involving urinary system genitourinary Both 0.778 0.995 0.963,1.03 4366 23262 0.9462 1.0 0.969,1.03 4286 22705
599.9 Other abnormality of urination genitourinary Both 0.4178 1.02 0.975,1.06 2349 20289 0.2773 1.02 0.981,1.07 2292 19802
600 Hyperplasia of prostate genitourinary Male 0.03388 0.955 0.916,0.996 3315 9437 0.02089 0.951 0.911,0.992 3223 9196
601 Inflammatory diseases of prostate genitourinary Male 0.618 0.982 0.914,1.05 825 7745 0.5754 1.05 0.877,1.27 122 1194
601.1 Prostatitis genitourinary Male 0.6516 0.976 0.879,1.08 378 3680 0.7656 1.04 0.821,1.31 76 739
601.11 Acute prostatitis genitourinary Male 0.879 1.02 0.83,1.24 95 933 0.9462 1.01 0.821,1.24 92 914
601.12 Chronic prostatitis genitourinary Male 0.8453 1.02 0.812,1.29 76 757 0.7656 1.04 0.821,1.31 76 739
601.3 Orchitis and epididymitis genitourinary Male 0.6324 1.03 0.916,1.16 303 3008 0.6683 1.03 0.913,1.15 299 2933
601.4 Balanoposthitis genitourinary Male 0.1432 0.86 0.703,1.05 103 1019 0.1671 0.864 0.703,1.06 99 989
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.6138 1.05 0.874,1.26 125 1226 0.5754 1.05 0.877,1.27 122 1194
602 Other disorders of prostate genitourinary Male 0.04677 0.882 0.778,0.998 277 2673 0.09772 0.899 0.793,1.02 273 2598
603 Other disorders of testis genitourinary Male 0.1074 1.09 0.981,1.22 348 3468 0.09333 1.16 0.975,1.39 124 1209
603.1 Hydrocele genitourinary Male 0.6823 1.03 0.899,1.18 229 2281 0.8337 1.01 0.886,1.16 225 2210
603.2 Spermatocele genitourinary Male 0.1091 1.15 0.969,1.38 126 1258 0.09333 1.16 0.975,1.39 124 1209
604 Disorders of penis genitourinary Male 0.9099 1.01 0.92,1.1 536 5321 0.6577 1.04 0.887,1.21 169 1650
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.5534 0.948 0.796,1.13 130 1297 0.5675 0.95 0.796,1.13 127 1265
604.3 Peyronie's disease genitourinary Male 0.6237 1.04 0.89,1.21 171 1703 0.6577 1.04 0.887,1.21 169 1650
605 Erectile dysfunction [ED] genitourinary Male 0.8531 0.996 0.955,1.04 2844 10666 0.912 0.998 0.957,1.04 2796 10374
608 Other disorders of male genital organs genitourinary Male 0.6026 1.02 0.959,1.07 1302 11530 0.5495 1.02 0.961,1.08 1284 11222
609 Male infertility and abnormal spermatozoa genitourinary Male 0.4093 0.953 0.851,1.07 335 3350 0.5546 1.06 0.874,1.29 118 1145
609.1 Infertility, male genitourinary Male 0.302 0.932 0.815,1.07 242 2420 0.2649 0.873 0.688,1.11 78 763
609.11 Azoospermia and oligospermia genitourinary Male 0.2312 0.866 0.684,1.1 79 789 0.2649 0.873 0.688,1.11 78 763
609.2 Abnormal spermatozoa genitourinary Male 0.5495 1.06 0.874,1.29 119 1185 0.5546 1.06 0.874,1.29 118 1145
610 Benign mammary dysplasias genitourinary Female 0.3908 1.02 0.978,1.06 3089 13905 0.26 1.04 0.973,1.11 1021 9921
610.1 Cystic mastopathy genitourinary Female 0.3319 1.03 0.972,1.09 1361 12011 0.3388 1.03 0.971,1.09 1331 11746
610.4 Benign neoplasm of breast genitourinary Female 0.507 1.01 0.972,1.06 2400 13828 0.4508 1.02 0.973,1.06 2346 13530
610.8 Other specified benign mammary dysplasias genitourinary Female 0.2377 1.04 0.975,1.11 1047 10149 0.26 1.04 0.973,1.11 1021 9921
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.8414 1.0 0.971,1.04 4952 15509 0.6486 0.991 0.952,1.03 2935 15116
611.1 Abnormal mammogram genitourinary Both 0.2838 1.02 0.984,1.06 4074 13538 0.07079 1.06 0.995,1.14 940 8933
611.11 Mammographic microcalcification genitourinary Both 0.09772 1.06 0.99,1.13 962 9131 0.07079 1.06 0.995,1.14 940 8933
611.3 Lump or mass in breast genitourinary Both 0.537 0.988 0.949,1.03 3011 15449 0.6486 0.991 0.952,1.03 2935 15116
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.1462 1.05 0.982,1.13 879 8768 0.09772 1.07 0.988,1.16 659 6553
612.1 Galactorrhea genitourinary Both 0.07586 1.18 0.983,1.42 109 1083 0.0871 1.18 0.976,1.43 102 1057
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.1429 1.06 0.98,1.15 672 6710 0.09772 1.07 0.988,1.16 659 6553
612.3 Congenital anomalies of breast genitourinary Both 0.2723 0.868 0.673,1.12 70 676 ,
613 Other nonmalignant breast conditions genitourinary Both 0.2864 1.02 0.983,1.06 3180 18154 0.2455 1.04 0.976,1.1 1165 11678
613.1 Inflammatory disease of breast genitourinary Both 0.526 1.03 0.941,1.13 504 5035 0.5105 1.03 0.941,1.13 495 4914
613.5 Mastodynia genitourinary Both 0.8995 1.0 0.948,1.06 1313 12942 0.9099 1.0 0.947,1.06 1278 12653
613.7 Other signs and symptoms in breast genitourinary Both 0.246 1.05 0.97,1.13 722 7109 0.1879 1.05 0.975,1.14 703 6953
613.8 Other specified disorders of breast genitourinary Both 0.7464 1.01 0.941,1.09 800 7961 0.6808 1.02 0.944,1.09 781 7771
613.9 Breast disorder NOS genitourinary Both 0.3581 1.03 0.969,1.09 1211 11947 0.2455 1.04 0.976,1.1 1165 11678
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.5741 1.01 0.972,1.05 2990 16271 0.2443 0.907 0.77,1.07 163 1579
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.5821 1.04 0.915,1.17 267 2670 0.5888 1.03 0.914,1.17 264 2598
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.9705 0.998 0.901,1.11 404 4024 0.1905 0.905 0.78,1.05 197 1915
614.31 Acute inflammatory pelvic disease genitourinary Female 0.6699 0.952 0.758,1.2 74 720 0.7112 0.958 0.763,1.2 74 700
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.4875 1.06 0.906,1.23 167 1666 0.4477 1.06 0.911,1.24 167 1634
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.1791 0.903 0.779,1.05 198 1979 0.1905 0.905 0.78,1.05 197 1915
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.5834 1.05 0.881,1.25 129 1290 0.4592 1.07 0.896,1.28 127 1253
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.6637 1.01 0.968,1.05 2546 16112 0.2443 0.907 0.77,1.07 163 1579
614.51 Cervicitis and endocervicitis genitourinary Female 0.9247 0.993 0.859,1.15 197 1970 0.8299 0.984 0.851,1.14 195 1935
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.6823 1.01 0.965,1.06 2201 15690 0.597 1.01 0.968,1.06 2163 15311
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.881 1.02 0.83,1.24 104 1040 0.9661 1.0 0.819,1.23 102 1019
614.54 Abscess or ulceration of vulva genitourinary Female 0.2208 0.903 0.767,1.06 164 1619 0.2443 0.907 0.77,1.07 163 1579
615 Endometriosis genitourinary Female 0.4797 0.98 0.925,1.04 1298 12230 0.4864 0.98 0.925,1.04 1279 11917
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.2748 1.03 0.976,1.09 1415 13522 0.2118 1.04 0.98,1.09 1400 13203
618 Genital prolapse genitourinary Female 0.7261 0.991 0.942,1.04 1707 14626 0.26 0.94 0.844,1.05 366 3642
618.1 Prolapse of vaginal walls genitourinary Female 0.8511 0.994 0.936,1.06 1179 11187 0.869 0.995 0.937,1.06 1164 10906
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.5534 1.03 0.934,1.14 444 4418 0.6397 1.02 0.928,1.13 436 4304
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.5321 0.962 0.851,1.09 286 2855 0.5636 0.964 0.852,1.09 281 2781
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.3141 0.947 0.851,1.05 375 3750 0.26 0.94 0.844,1.05 366 3642
619 Noninflammatory female genital disorders genitourinary Female 0.4121 1.01 0.981,1.05 4598 15534 0.4529 1.03 0.959,1.1 902 8854
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.7261 1.01 0.953,1.07 1262 11294 0.6209 1.01 0.957,1.08 1245 11023
619.2 Disorders of uterus, NEC genitourinary Female 0.3105 1.05 0.955,1.16 444 4435 0.514 1.03 0.937,1.14 432 4334
619.3 Noninflammatory disorders of cervix genitourinary Female 0.4887 1.04 0.935,1.15 391 3892 0.2786 1.06 0.954,1.18 381 3820
619.4 Noninflammatory disorders of vagina genitourinary Female 0.1663 1.03 0.986,1.08 1903 15019 0.1199 1.04 0.99,1.09 1875 14666
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.4753 1.03 0.958,1.1 914 9082 0.4529 1.03 0.959,1.1 902 8854
620 Dysplasia of female genital organs genitourinary Female 0.9462 1.0 0.897,1.12 325 3234 0.7244 1.03 0.87,1.22 140 1392
620.1 Dysplasia of cervix genitourinary Female 0.6039 1.05 0.883,1.24 142 1420 0.7244 1.03 0.87,1.22 140 1392
621 Endometrial hyperplasia genitourinary Female 0.7691 1.02 0.91,1.14 334 3335 0.7015 1.02 0.914,1.14 326 3247
622 Polyp of female genital organs genitourinary Female 0.16 1.04 0.983,1.11 1191 11723 0.09333 1.1 0.985,1.23 340 3398
622.1 Polyp of corpus uteri genitourinary Female 0.3573 1.03 0.965,1.1 949 9362 0.3258 1.03 0.967,1.11 934 9133
622.2 Mucous polyp of cervix genitourinary Female 0.1294 1.09 0.976,1.21 348 3480 0.09333 1.1 0.985,1.23 340 3398
623 Hypertrophy of female genital organs genitourinary Female 0.9036 0.995 0.914,1.08 605 6003 0.8241 0.99 0.91,1.08 603 5871
624 Symptoms involving female genital tract genitourinary Female 0.03631 1.07 1.0,1.14 1013 9695 0.5309 1.02 0.965,1.07 1528 12589
624.1 Dystrophy of female genital tract genitourinary Female 0.2223 1.1 0.942,1.29 168 1680 0.1923 1.11 0.948,1.31 164 1645
624.9 stress incontinence, female genitourinary Female 0.7178 1.01 0.958,1.06 1549 12918 0.5309 1.02 0.965,1.07 1528 12589
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.2917 1.02 0.985,1.05 4618 14394 0.9528 1.0 0.939,1.07 998 9826
625.1 Dyspareunia genitourinary Female 0.9268 1.0 0.941,1.07 1011 10081 0.9528 1.0 0.939,1.07 998 9826
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.1824 1.02 0.989,1.06 4726 13065 0.7816 0.988 0.91,1.07 624 5094
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.4467 1.02 0.977,1.06 3426 12112 0.07413 0.895 0.793,1.01 297 2937
626.11 Absent or infrequent menstruation genitourinary Female 0.8913 0.995 0.925,1.07 802 6948 0.9078 0.996 0.925,1.07 787 6783
626.12 Excessive or frequent menstruation genitourinary Female 0.3373 1.03 0.974,1.08 1703 9843 0.3319 1.03 0.974,1.08 1679 9602
626.13 Irregular menstrual cycle genitourinary Female 0.8128 0.993 0.941,1.05 1543 10197 0.8222 0.994 0.941,1.05 1515 9936
626.14 Irregular menstrual bleeding genitourinary Female 0.6067 1.02 0.947,1.1 777 7408 0.4753 1.03 0.954,1.11 764 7228
626.15 Infertility, female, associated with anovulation genitourinary Female 0.05754 0.889 0.788,1.0 300 3000 0.07413 0.895 0.793,1.01 297 2937
626.2 Dysmenorrhea genitourinary Female 0.7962 0.992 0.931,1.06 1116 8297 0.811 0.992 0.932,1.06 1100 8096
626.4 Premenstrual tension syndromes genitourinary Female 0.6546 0.972 0.859,1.1 275 2741 0.6281 0.97 0.856,1.1 270 2681
626.8 Infertility, female genitourinary Female 0.6714 0.982 0.904,1.07 630 5218 0.7816 0.988 0.91,1.07 624 5094
627 Menopausal and postmenopausal disorders genitourinary Female 0.389 1.02 0.979,1.06 3657 12296 0.2624 0.924 0.804,1.06 225 2278
627.1 Postmenopausal bleeding genitourinary Female 0.1563 1.05 0.982,1.12 957 8768 0.1637 1.05 0.981,1.12 935 8543
627.2 Symptomatic menopause genitourinary Female 0.8299 1.0 0.962,1.05 2443 11667 0.5808 0.966 0.856,1.09 292 2867
627.21 Symptomatic artificial menopause genitourinary Female 0.2661 1.11 0.925,1.32 125 1241 0.1845 1.13 0.943,1.36 123 1214
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.5572 0.965 0.855,1.09 295 2948 0.5808 0.966 0.856,1.09 292 2867
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.07244 1.07 0.994,1.16 729 7262 0.09333 1.07 0.989,1.15 711 7072
627.4 Premenopausal menorrhagia genitourinary Female 0.5 1.04 0.926,1.17 305 3020 0.4508 1.05 0.93,1.18 297 2939
627.5 Premature menopause and other ovarian failure genitourinary Female 0.2153 0.918 0.801,1.05 234 2340 0.2624 0.924 0.804,1.06 225 2278
628 Ovarian cyst genitourinary Female 0.7031 0.99 0.94,1.04 1619 11554 0.8933 0.996 0.945,1.05 1589 11269
634 Miscarriage; stillbirth pregnancy complications Female 0.2366 0.952 0.879,1.03 648 6413 0.5636 1.06 0.866,1.3 95 921
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.5702 0.96 0.834,1.11 209 2090 0.6109 0.964 0.836,1.11 208 2048
634.3 Ectopic pregnancy pregnancy complications Female 0.5848 1.06 0.864,1.3 95 950 0.5636 1.06 0.866,1.3 95 921
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.2393 1.06 0.96,1.18 414 4070 0.2818 1.08 0.938,1.25 204 2020
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.3133 1.07 0.942,1.21 272 2720 0.2799 1.07 0.946,1.21 268 2659
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.3273 1.07 0.932,1.24 206 2060 0.2818 1.08 0.938,1.25 204 2020
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.5383 1.02 0.952,1.1 855 6402 0.4355 1.11 0.853,1.45 60 587
636.1 Threatened premature labor pregnancy complications Female 0.5176 0.961 0.853,1.08 298 2980 0.6339 0.971 0.861,1.1 294 2919
636.2 Early onset of delivery pregnancy complications Female 0.7112 1.03 0.898,1.17 233 2330 0.6383 1.03 0.904,1.18 231 2279
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.9638 1.0 0.899,1.12 356 3556 0.8933 1.01 0.904,1.12 355 3475
636.8 Cervical incompetence pregnancy complications Female 0.4305 1.11 0.854,1.45 60 600 0.4355 1.11 0.853,1.45 60 587
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.9908 1.0 0.806,1.24 89 884 0.9954 0.999 0.801,1.25 86 857
638 Other high-risk pregnancy pregnancy complications Female 0.9311 1.0 0.933,1.08 818 5867 0.7834 1.01 0.939,1.09 802 5742
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.7178 0.982 0.888,1.09 421 4210 0.3516 1.07 0.929,1.23 210 2113
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.3963 1.06 0.924,1.22 215 2150 0.3516 1.07 0.929,1.23 210 2113
643 Excessive vomiting in pregnancy pregnancy complications Female 0.2735 1.09 0.935,1.27 181 1810 0.2296 1.14 0.919,1.42 84 851
643.1 Hyperemesis gravidarum pregnancy complications Female 0.2084 1.15 0.926,1.42 87 870 0.2296 1.14 0.919,1.42 84 851
644 Anemia during pregnancy pregnancy complications Female 0.975 0.997 0.844,1.18 154 1540 0.9886 0.999 0.845,1.18 152 1510
645 Late pregnancy and failed induction pregnancy complications Female 0.1791 1.09 0.963,1.22 286 2860 0.2089 1.08 0.958,1.22 284 2804
646 Other complications of pregnancy NEC pregnancy complications Female 0.7907 1.01 0.931,1.1 622 5063 0.6561 1.02 0.938,1.11 613 4969
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.7762 0.977 0.83,1.15 152 1520 0.2992 0.922 0.792,1.07 179 1789
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.3475 0.93 0.799,1.08 182 1820 0.2992 0.922 0.792,1.07 179 1789
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.5702 1.02 0.953,1.09 968 6387 0.2761 1.06 0.956,1.17 404 4053
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.3899 1.05 0.945,1.16 413 4130 0.2761 1.06 0.956,1.17 404 4053
650 Normal delivery pregnancy complications Female 0.7907 1.01 0.937,1.09 757 6412 0.6792 1.02 0.942,1.1 748 6274
651 Multiple gestation pregnancy complications Female 0.4613 1.08 0.881,1.32 100 1000 0.4457 1.08 0.883,1.33 99 979
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.03548 1.11 1.01,1.22 461 4586 0.02455 1.11 1.01,1.23 454 4490
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.7311 1.02 0.922,1.12 443 4189 0.6761 1.02 0.925,1.13 441 4105
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.875 0.992 0.904,1.09 482 4820 0.1127 1.14 0.97,1.33 161 1592
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.3076 1.05 0.952,1.17 402 4020 0.2636 1.06 0.957,1.18 398 3930
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.1524 1.12 0.958,1.32 163 1630 0.1127 1.14 0.97,1.33 161 1592
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.2673 1.03 0.974,1.1 1244 8117 0.5346 1.03 0.936,1.14 444 4275
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.6266 1.02 0.93,1.13 451 4371 0.5346 1.03 0.936,1.14 444 4275
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.8185 1.02 0.888,1.16 246 2460 0.4624 0.9 0.68,1.19 58 570
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.389 0.885 0.671,1.17 59 590 0.4624 0.9 0.68,1.19 58 570
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.3724 0.936 0.808,1.08 195 1950 0.3873 0.938 0.81,1.09 194 1908
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.8551 1.01 0.92,1.11 504 4732 0.8375 1.01 0.92,1.11 498 4639
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.6194 1.03 0.928,1.13 420 4080 0.52 1.03 0.934,1.14 414 3991
665 Obstetrical/birth trauma pregnancy complications Female 0.4036 1.03 0.958,1.11 751 6161 0.3133 1.04 0.964,1.12 742 6022
669 Complications of labor and delivery NEC pregnancy complications Female 0.2871 1.04 0.964,1.13 671 5265 0.2576 1.05 0.966,1.14 664 5156
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.1734 1.11 0.954,1.3 172 1720 0.1135 1.14 0.97,1.33 166 1682
674 Other complications of the puerperium NEC pregnancy complications Female 0.7745 0.978 0.838,1.14 181 1810 0.871 0.987 0.844,1.15 177 1781
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.1738 1.13 0.947,1.35 122 1220 0.1791 1.13 0.945,1.35 119 1197
681 Superficial cellulitis and abscess dermatologic Both 0.5152 0.99 0.961,1.02 5078 31991 0.0955 0.951 0.896,1.01 1202 12052
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.9661 1.0 0.934,1.07 862 8581 0.8318 0.992 0.925,1.06 846 8396
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.8185 0.991 0.921,1.07 781 7775 0.9817 1.0 0.929,1.08 758 7614
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.5957 1.01 0.962,1.07 1533 15238 0.5224 1.02 0.965,1.07 1488 14916
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.4246 1.02 0.971,1.07 1649 16359 0.3811 1.02 0.972,1.08 1599 16026
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.5821 1.02 0.96,1.08 1291 12850 0.5272 1.02 0.961,1.08 1251 12570
681.7 Cellulitis and abscess of trunk dermatologic Both 0.1807 0.961 0.906,1.02 1238 12342 0.0955 0.951 0.896,1.01 1202 12052
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.5495 1.02 0.966,1.07 1660 16466 0.1178 1.16 0.963,1.4 117 1187
686.1 Carbuncle and furuncle dermatologic Both 0.4808 0.963 0.868,1.07 390 3881 0.3882 0.954 0.858,1.06 381 3788
686.2 Impetigo dermatologic Both 0.1343 1.09 0.973,1.23 310 3068 0.0871 1.11 0.985,1.25 297 2999
686.3 Pilonidal cyst dermatologic Both 0.125 0.862 0.713,1.04 120 1200 0.1521 0.869 0.718,1.05 117 1171
686.4 Pyogenic granuloma dermatologic Both 0.1462 1.15 0.954,1.38 121 1205 0.1178 1.16 0.963,1.4 117 1187
687 Symptoms affecting skin dermatologic Both 0.9226 1.0 0.974,1.03 6119 25901 0.6501 1.01 0.976,1.04 4757 25144
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.2075 1.02 0.989,1.05 5371 25824 0.2254 1.02 0.989,1.05 5214 25380
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.826 1.0 0.974,1.03 5264 25870 0.929 0.999 0.969,1.03 5002 25424
687.3 Changes in skin texture dermatologic Both 0.4102 0.951 0.843,1.07 294 2926 0.2667 0.933 0.826,1.05 287 2875
687.4 Disturbance of skin sensation dermatologic Both 0.875 1.0 0.972,1.03 4942 25586 0.6501 1.01 0.976,1.04 4757 25144
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.2624 1.01 0.989,1.04 7192 31086 0.228 1.02 0.99,1.04 7001 30373
690 Erythematosquamous dermatosis dermatologic Both 0.5861 0.991 0.957,1.03 3810 26256 0.7244 0.994 0.96,1.03 3720 25573
690.1 Seborrheic dermatitis dermatologic Both 0.5998 0.991 0.957,1.03 3802 26218 0.7244 0.994 0.96,1.03 3720 25573
691 Congenital anomalies of skin dermatologic Both 0.02512 1.12 1.01,1.24 411 4110 0.0182 1.13 1.02,1.25 406 4012
694 Dyschromia and Vitiligo dermatologic Both 0.7816 1.01 0.952,1.07 1286 12819 0.6918 0.95 0.736,1.23 66 667
694.1 Vitiligo dermatologic Both 0.3733 1.1 0.89,1.36 94 931 0.2931 1.12 0.904,1.4 92 904
694.2 Other dyschromia dermatologic Both 0.6622 1.01 0.954,1.08 1146 11421 0.5636 1.02 0.958,1.08 1127 11147
694.3 Vascular disorders of skin dermatologic Both 0.4732 0.912 0.71,1.17 69 686 0.6918 0.95 0.736,1.23 66 667
695 Erythematous conditions dermatologic Both 0.4335 1.01 0.978,1.05 3180 24642 0.0302 1.11 1.01,1.21 493 4971
695.2 Bullous dermatoses dermatologic Both 0.2667 0.86 0.66,1.12 68 658 0.2799 0.864 0.663,1.13 68 643
695.3 Rosacea dermatologic Both 0.9886 1.0 0.946,1.06 1405 14019 0.8241 1.01 0.952,1.06 1381 13647
695.4 Lupus (localized and systemic) dermatologic Both 0.2748 1.05 0.963,1.14 556 5556 0.3963 1.04 0.951,1.14 522 5153
695.41 Cutaneous lupus erythematosus dermatologic Both 0.7278 1.03 0.889,1.18 196 1955 0.7379 1.02 0.888,1.18 193 1906
695.42 Systemic lupus erythematosus dermatologic Both 0.4246 1.04 0.949,1.13 530 5287 0.3963 1.04 0.951,1.14 522 5153
695.7 Prurigo and Lichen dermatologic Both 0.1972 1.07 0.967,1.17 429 4275 0.1489 1.07 0.975,1.19 426 4165
695.8 Other specified erythematous conditions dermatologic Both 0.9705 1.0 0.922,1.09 613 6111 0.9772 0.999 0.918,1.09 602 5957
695.9 Unspecified erythematous condition dermatologic Both 0.04571 1.1 1.0,1.2 513 5102 0.0302 1.11 1.01,1.21 493 4971
696 Psoriasis and related disorders dermatologic Both 0.4046 1.03 0.965,1.09 1080 10781 0.2761 1.08 0.943,1.23 222 2195
696.3 Pityriasis dermatologic Both 0.859 1.02 0.793,1.32 64 640 0.8279 1.03 0.795,1.33 63 630
696.4 Psoriasis dermatologic Both 0.3846 1.03 0.965,1.1 1014 10115 0.2761 1.08 0.943,1.23 222 2195
696.41 Psoriasis vulgaris dermatologic Both 0.5675 1.02 0.953,1.09 918 9161 0.5395 1.02 0.954,1.09 898 8932
696.42 Psoriatic arthropathy dermatologic Both 0.3013 1.07 0.939,1.22 225 2250 0.2761 1.08 0.943,1.23 222 2195
697 Sarcoidosis dermatologic Both 0.1294 1.1 0.972,1.25 265 2650 0.1888 1.09 0.959,1.23 261 2577
698 Pruritus and related conditions dermatologic Both 0.5754 1.01 0.965,1.07 1686 16680 0.5236 1.02 0.966,1.07 1634 16288
700 Corns and callosities dermatologic Both 0.369 1.03 0.96,1.11 764 7615 0.5297 1.02 0.95,1.1 750 7420
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.6855 0.994 0.967,1.02 5838 31889 0.9247 1.01 0.893,1.13 317 3185
701.1 Keratoderma, acquired dermatologic Both 0.5728 0.97 0.874,1.08 389 3845 0.6252 0.974 0.876,1.08 382 3764
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.5861 1.01 0.965,1.07 1705 16953 0.778 1.01 0.958,1.06 1667 16542
701.3 Circumscribed scleroderma dermatologic Both 0.507 0.968 0.878,1.07 434 4334 0.5521 0.971 0.88,1.07 427 4238
701.4 Keloid scar dermatologic Both 0.006918 0.874 0.793,0.964 454 4503 0.006026 0.871 0.789,0.961 446 4401
701.5 Abnormal granulation tissue dermatologic Both 0.8492 1.01 0.9,1.14 328 3260 0.9247 1.01 0.893,1.13 317 3185
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.2624 0.983 0.954,1.01 5351 24908 0.8185 1.03 0.8,1.33 63 608
702.1 Actinic keratosis dermatologic Both 0.5559 0.989 0.952,1.03 3236 22206 0.5649 0.989 0.952,1.03 3162 21655
702.2 Seborrheic keratosis dermatologic Both 0.1486 0.976 0.944,1.01 4151 26248 0.1986 0.978 0.946,1.01 4058 25589
702.4 Degenerative skin disorders dermatologic Both 0.8035 1.03 0.801,1.33 63 624 0.8185 1.03 0.8,1.33 63 608
703 Diseases of nail, NOS dermatologic Both 0.1303 0.952 0.893,1.01 1033 10222 0.3936 1.04 0.953,1.13 567 5634
703.1 Ingrowing nail dermatologic Both 0.2761 1.05 0.963,1.14 580 5773 0.3936 1.04 0.953,1.13 567 5634
704 Diseases of hair and hair follicles dermatologic Both 0.6745 0.991 0.949,1.03 2321 22718 0.6668 1.01 0.955,1.07 1247 12504
704.1 Alopecia dermatologic Both 0.1995 0.959 0.901,1.02 1074 10601 0.7943 1.03 0.804,1.33 57 566
704.11 Alopecia Areata dermatologic Both 0.865 1.02 0.797,1.31 58 580 0.7943 1.03 0.804,1.33 57 566
704.2 Hirsutism dermatologic Both 0.6442 0.968 0.845,1.11 227 2263 0.6637 0.97 0.846,1.11 226 2222
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.5834 1.02 0.959,1.08 1286 12791 0.6668 1.01 0.955,1.07 1247 12504
705 Disorders of sweat glands dermatologic Both 0.4775 1.04 0.94,1.14 439 4376 0.975 0.999 0.93,1.07 824 8226
705.1 Dyshidrosis dermatologic Both 0.2704 0.896 0.738,1.09 114 1131 0.3069 0.903 0.743,1.1 114 1101
705.3 Hidradenitis dermatologic Both 0.2388 1.09 0.942,1.27 183 1815 0.2438 1.09 0.941,1.27 180 1767
705.8 Hyperhidrosis dermatologic Both 0.9727 0.999 0.931,1.07 846 8429 0.975 0.999 0.93,1.07 824 8226
706 Diseases of sebaceous glands dermatologic Both 0.5689 1.01 0.978,1.04 4454 32859 0.8072 0.992 0.932,1.06 1093 10878
706.1 Acne dermatologic Both 0.3162 1.02 0.977,1.07 1931 17499 0.2679 1.03 0.98,1.08 1896 17096
706.2 Sebaceous cyst dermatologic Both 0.5236 1.01 0.971,1.06 2150 21106 0.5152 1.02 0.97,1.06 2096 20576
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.9333 0.997 0.938,1.06 1124 11122 0.8072 0.992 0.932,1.06 1093 10878
707 Chronic ulcer of skin dermatologic Both 0.7328 1.01 0.964,1.05 2193 21811 0.6457 0.987 0.932,1.04 1305 13045
707.1 Decubitus ulcer dermatologic Both 0.5 1.03 0.946,1.12 600 5984 0.5636 1.03 0.941,1.12 575 5832
707.2 Chronic ulcer of leg or foot dermatologic Both 0.2432 1.05 0.97,1.13 721 7166 0.2061 1.05 0.973,1.13 703 6977
707.3 Chronic ulcer of unspecified site dermatologic Both 0.5957 0.985 0.931,1.04 1339 13370 0.6457 0.987 0.932,1.04 1305 13045
709 Diffuse diseases of connective tissue dermatologic Both 0.875 1.01 0.944,1.07 1086 10825 0.8872 0.994 0.917,1.08 648 6395
709.2 Sicca syndrome dermatologic Both 0.07244 1.1 0.991,1.22 365 3650 0.06457 1.1 0.994,1.23 355 3573
709.3 Systemic sclerosis dermatologic Both 0.1718 0.9 0.773,1.05 184 1840 0.2075 0.907 0.779,1.06 182 1799
709.5 Dermatomyositis dermatologic Both 0.6714 0.95 0.749,1.21 70 700 0.7798 0.966 0.757,1.23 67 680
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.6792 1.05 0.832,1.33 78 780 0.7129 1.05 0.826,1.32 77 767
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.7962 0.989 0.913,1.07 659 6563 0.8872 0.994 0.917,1.08 648 6395
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.3828 1.01 0.983,1.04 5120 27320 0.8511 1.02 0.798,1.31 63 615
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.7834 1.03 0.81,1.32 64 626 0.8511 1.02 0.798,1.31 63 615
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.7889 0.991 0.927,1.06 954 9524 0.7925 0.99 0.922,1.06 835 8421
710.1 Osteomyelitis musculoskeletal Both 0.7834 0.99 0.925,1.06 914 9127 0.7925 0.99 0.922,1.06 835 8421
710.11 Acute osteomyelitis musculoskeletal Both 0.5445 1.03 0.934,1.14 425 4234 0.4721 1.04 0.938,1.15 408 4113
710.12 Chronic osteomyelitis musculoskeletal Both 0.6607 0.976 0.878,1.09 378 3758 0.9057 0.993 0.891,1.11 364 3660
710.19 Unspecified osteomyelitis musculoskeletal Both 0.7568 0.989 0.922,1.06 867 8656 0.7925 0.99 0.922,1.06 835 8421
711 Arthropathy associated with infections musculoskeletal Both 0.8974 0.992 0.884,1.11 314 3124 0.9772 1.0 0.872,1.15 219 2149
711.1 Pyogenic arthritis musculoskeletal Both 0.9727 0.998 0.868,1.15 223 2206 0.9772 1.0 0.872,1.15 219 2149
712 Infective connective tissue disorders musculoskeletal Both 0.4688 1.07 0.893,1.28 136 1360 0.3516 1.09 0.909,1.31 134 1332
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.5 0.953 0.828,1.1 222 2214 0.4842 0.934 0.771,1.13 115 1156
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.4046 0.923 0.764,1.11 118 1180 0.4842 0.934 0.771,1.13 115 1156
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.3357 1.03 0.974,1.08 1649 14662 0.3811 1.03 0.969,1.09 1319 12010
714.1 Rheumatoid arthritis musculoskeletal Both 0.5188 1.02 0.963,1.08 1342 12332 0.3811 1.03 0.969,1.09 1319 12010
715 Other inflammatory spondylopathies musculoskeletal Both 0.869 1.01 0.942,1.07 979 9761 0.1222 1.13 0.968,1.32 171 1706
715.1 Sacroiliitis NEC musculoskeletal Both 0.4819 0.951 0.828,1.09 212 2120 0.7161 0.974 0.847,1.12 207 2059
715.2 Ankylosing spondylitis musculoskeletal Both 0.2046 1.1 0.948,1.28 177 1760 0.1222 1.13 0.968,1.32 171 1706
716 Other arthropathies musculoskeletal Both 0.9036 0.999 0.976,1.02 10893 26011 0.8395 1.0 0.979,1.03 10609 25366
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.7889 1.02 0.864,1.21 155 1540 0.6427 1.04 0.878,1.24 153 1508
716.2 Unspecified monoarthritis musculoskeletal Both 0.04571 1.21 1.0,1.45 116 1156 0.04677 1.21 1.0,1.46 114 1120
716.9 Arthropathy NOS musculoskeletal Both 0.9099 0.999 0.976,1.02 10831 26002 0.8395 1.0 0.979,1.03 10609 25366
717 Polymyalgia Rheumatica musculoskeletal Both 0.6109 1.04 0.901,1.19 210 2061 0.5794 1.04 0.903,1.2 206 2013
720 Spinal stenosis musculoskeletal Both 0.7328 0.994 0.958,1.03 3298 24117 0.4046 1.02 0.976,1.06 2360 20023
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.52 1.01 0.972,1.06 2415 20454 0.4046 1.02 0.976,1.06 2360 20023
721 Spondylosis and allied disorders musculoskeletal Both 0.4426 0.988 0.957,1.02 4494 27007 0.3319 0.929 0.802,1.08 199 2056
721.1 Spondylosis without myelopathy musculoskeletal Both 0.6839 0.993 0.961,1.03 4206 26584 0.8147 0.996 0.963,1.03 4077 26010
721.2 Spondylosis with myelopathy musculoskeletal Both 0.1012 0.939 0.87,1.01 740 7398 0.1282 0.942 0.872,1.02 714 7238
721.8 Other allied disorders of spine musculoskeletal Both 0.2084 0.912 0.79,1.05 212 2099 0.3319 0.929 0.802,1.08 199 2056
722 Intervertebral disc disorders musculoskeletal Both 0.8872 0.998 0.969,1.03 5242 28702 0.6397 1.01 0.961,1.07 1525 15322
722.1 Displacement of intervertebral disc musculoskeletal Both 0.7047 0.993 0.956,1.03 3038 26827 0.9057 0.998 0.96,1.04 2952 26263
722.3 Schmorl's nodes musculoskeletal Both 0.07079 1.19 0.985,1.43 115 1140 0.1368 1.16 0.954,1.41 106 1113
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.4592 0.986 0.951,1.02 3338 26140 0.7586 0.994 0.958,1.03 3249 25586
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.4539 0.964 0.876,1.06 464 4634 0.7079 0.982 0.891,1.08 455 4536
722.8 Postlaminectomy syndrome musculoskeletal Both 0.6081 1.03 0.921,1.15 336 3360 0.4169 1.05 0.937,1.17 333 3294
722.9 Other and unspecified disc disorder musculoskeletal Both 0.7278 1.01 0.959,1.06 1569 15676 0.6397 1.01 0.961,1.07 1525 15322
723 Other disorders of cervical region musculoskeletal Both 0.7079 1.01 0.942,1.09 761 7610 0.6081 1.04 0.893,1.21 181 1824
723.1 Torticollis musculoskeletal Both 0.7031 1.03 0.885,1.2 187 1870 0.6081 1.04 0.893,1.21 181 1824
724 Other and unspecified disorders of back musculoskeletal Both 0.07413 0.967 0.933,1.0 3338 26730 0.7447 0.99 0.933,1.05 1194 12161
724.1 Disorders of sacrum musculoskeletal Both 0.06761 0.955 0.91,1.0 1804 17663 0.08128 0.957 0.911,1.01 1772 17299
724.2 Disorders of coccyx musculoskeletal Both 0.1054 0.91 0.812,1.02 331 3290 0.09333 0.906 0.808,1.02 328 3229
724.8 Other symptoms referable to back musculoskeletal Both 0.811 1.01 0.936,1.09 753 7499 0.5559 1.02 0.948,1.1 735 7329
724.9 Other unspecified back disorders musculoskeletal Both 0.7638 0.991 0.935,1.05 1246 12418 0.7447 0.99 0.933,1.05 1194 12161
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.1603 0.982 0.957,1.01 7682 25455 0.9354 1.0 0.935,1.08 872 8634
726.1 Enthesopathy musculoskeletal Both 0.09772 0.976 0.948,1.0 5795 25454 0.113 0.977 0.949,1.01 5699 24868
726.2 Synoviopathy musculoskeletal Both 0.3258 1.04 0.964,1.12 774 7723 0.278 1.04 0.967,1.12 763 7528
726.3 Bursitis musculoskeletal Both 0.6109 1.01 0.959,1.07 1339 13090 0.5702 1.02 0.961,1.08 1320 12780
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.9954 1.0 0.932,1.07 889 8846 0.9354 1.0 0.935,1.08 872 8634
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.4436 0.989 0.961,1.02 5811 25457 0.3516 0.912 0.751,1.11 115 1092
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.3819 0.981 0.939,1.02 2342 20541 0.4808 0.984 0.942,1.03 2307 20070
727.2 Bursitis disorders musculoskeletal Both 0.6124 1.03 0.922,1.15 341 3381 0.5508 1.03 0.926,1.16 335 3302
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.6823 0.987 0.928,1.05 1109 11034 0.7278 0.989 0.929,1.05 1086 10762
727.5 Rupture of synovium musculoskeletal Both 0.7907 0.986 0.888,1.09 376 3718 0.8551 0.99 0.891,1.1 366 3630
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.7907 1.01 0.96,1.05 1927 18092 0.6266 1.01 0.965,1.06 1896 17660
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.6353 1.02 0.934,1.12 520 5187 0.6561 1.02 0.932,1.12 507 5077
727.8 Plica syndrome musculoskeletal Both 0.3319 0.908 0.748,1.1 115 1117 0.3516 0.912 0.751,1.11 115 1092
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.9772 1.0 0.965,1.04 3433 24951 0.455 1.05 0.93,1.17 304 3023
728.1 Muscular calcification and ossification musculoskeletal Both 0.7079 0.953 0.741,1.23 69 682 0.9817 0.997 0.772,1.29 65 667
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.2506 0.921 0.801,1.06 230 2298 0.2198 0.915 0.794,1.05 223 2236
728.7 Fasciitis musculoskeletal Both 0.9661 1.0 0.956,1.05 2056 19042 0.455 1.05 0.93,1.17 304 3023
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.415 1.05 0.935,1.18 310 3095 0.455 1.05 0.93,1.17 304 3023
729 Other disorders of soft tissues musculoskeletal Both 0.4111 1.02 0.977,1.06 2618 22751 0.08318 1.29 0.968,1.71 52 513
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.4198 0.897 0.689,1.17 63 630 0.3954 0.89 0.68,1.16 62 607
729.3 Panniculitis musculoskeletal Both 0.5768 1.06 0.868,1.29 100 1000 0.7762 1.03 0.841,1.26 99 982
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.05248 1.32 0.997,1.75 53 530 0.08318 1.29 0.968,1.71 52 513
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.9441 1.01 0.847,1.2 145 1441 0.9863 0.999 0.839,1.19 141 1395
732 Osteochondropathies musculoskeletal Both 0.2649 0.933 0.826,1.05 289 2882 0.4699 0.916 0.723,1.16 71 692
732.1 Juvenile osteochondrosis musculoskeletal Both 0.6012 1.04 0.888,1.23 157 1570 0.5728 1.05 0.89,1.24 155 1532
732.7 Osteochondritis dissecans musculoskeletal Both 0.507 0.924 0.73,1.17 71 710 0.4699 0.916 0.723,1.16 71 692
733 Other disorders of bone and cartilage musculoskeletal Both 0.5495 1.01 0.975,1.05 3481 21966 0.857 1.02 0.809,1.29 79 776
733.2 Cyst of bone musculoskeletal Both 0.3475 1.08 0.921,1.26 162 1613 0.2477 1.1 0.936,1.29 157 1577
733.4 Aseptic necrosis of bone musculoskeletal Both 0.9594 0.997 0.903,1.1 405 4042 0.9528 1.0 0.906,1.11 385 3941
733.6 Costochondritis musculoskeletal Both 0.8892 1.01 0.892,1.14 275 2742 0.929 1.01 0.888,1.14 265 2684
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.3148 0.96 0.888,1.04 701 7003 0.3055 0.959 0.886,1.04 689 6856
733.9 Chondromalacia musculoskeletal Both 0.9183 0.988 0.783,1.25 80 800 0.857 1.02 0.809,1.29 79 776
735 Acquired foot deformities musculoskeletal Both 0.871 1.0 0.962,1.05 2431 23304 0.8166 1.01 0.945,1.07 1021 10086
735.1 Flat foot musculoskeletal Both 0.7656 0.985 0.892,1.09 437 4355 0.7943 0.987 0.893,1.09 426 4250
735.2 Acquired toe deformities musculoskeletal Both 0.6012 0.982 0.916,1.05 869 8616 0.4227 1.05 0.932,1.18 293 2905
735.21 Hammer toe (acquired) musculoskeletal Both 0.3013 0.953 0.87,1.04 509 5041 0.3214 0.955 0.871,1.05 501 4928
735.23 Hallux rigidus musculoskeletal Both 0.5598 1.04 0.92,1.17 299 2975 0.4227 1.05 0.932,1.18 293 2905
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.9268 1.0 0.941,1.07 1039 10308 0.8166 1.01 0.945,1.07 1021 10086
736 Other acquired deformities of limbs musculoskeletal Both 0.9661 1.0 0.956,1.05 1997 19771 0.8054 1.02 0.89,1.16 250 2507
736.1 Acquired deformities of forearm musculoskeletal Both 0.5224 1.07 0.869,1.32 90 892 0.4227 1.09 0.884,1.34 88 872
736.2 Acquired deformities of finger musculoskeletal Both 0.8356 1.02 0.871,1.19 169 1684 0.778 1.02 0.875,1.19 168 1647
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.6998 0.974 0.853,1.11 239 2382 0.7551 0.979 0.856,1.12 237 2331
736.5 Acquired deformities of knee musculoskeletal Both 0.5572 0.956 0.821,1.11 184 1834 0.6745 0.968 0.83,1.13 180 1790
736.6 Unequal leg length (acquired) musculoskeletal Both 0.8531 1.01 0.888,1.15 256 2555 0.8054 1.02 0.89,1.16 250 2507
737 Curvature of spine musculoskeletal Both 0.6653 0.987 0.932,1.05 1268 12573 0.3733 0.97 0.908,1.04 962 9559
737.1 Kyphosis (acquired) musculoskeletal Both 0.6486 0.976 0.881,1.08 383 3819 0.6776 0.978 0.881,1.09 363 3737
737.2 Lordosis (acquired) musculoskeletal Both 0.2123 1.17 0.916,1.48 65 650 0.2818 1.14 0.896,1.46 64 632
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.2812 0.965 0.903,1.03 987 9782 0.3733 0.97 0.908,1.04 962 9559
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.7603 0.993 0.948,1.04 1968 19555 0.4699 1.03 0.957,1.1 845 8424
738.4 Acquired spondylolisthesis musculoskeletal Both 0.4677 1.03 0.958,1.1 863 8617 0.4699 1.03 0.957,1.1 845 8424
739 Contracture of joint musculoskeletal Both 0.2535 1.05 0.964,1.15 522 5203 0.2612 1.05 0.963,1.15 507 5077
740 Osteoarthrosis musculoskeletal Both 0.2432 0.987 0.965,1.01 13133 25195 0.5495 0.993 0.971,1.02 12381 24449
740.1 Osteoarthritis; localized musculoskeletal Both 0.3758 0.986 0.956,1.02 5329 22764 0.1919 0.941 0.859,1.03 508 5008
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.4207 0.987 0.955,1.02 4543 21500 0.6039 0.991 0.959,1.02 4472 20941
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.1578 0.937 0.856,1.03 514 5125 0.1919 0.941 0.859,1.03 508 5008
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.4093 1.03 0.966,1.09 1266 9917 0.2825 1.03 0.973,1.1 1250 9672
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.01738 1.15 1.03,1.29 303 2974 0.008913 1.17 1.04,1.31 302 2906
740.9 Osteoarthrosis NOS musculoskeletal Both 0.3076 0.988 0.966,1.01 12648 25075 0.5495 0.993 0.971,1.02 12381 24449
741 Symptoms and disorders of the joints musculoskeletal Both 0.7031 1.01 0.979,1.03 6764 29838 0.3981 1.13 0.853,1.49 53 510
741.1 Ankylosis of joint musculoskeletal Both 0.7278 0.975 0.847,1.12 209 2088 0.7261 0.975 0.847,1.12 208 2038
741.2 Stiffness of joint musculoskeletal Both 0.4111 1.03 0.963,1.1 995 9908 0.4406 1.03 0.96,1.1 970 9685
741.3 Difficulty in walking musculoskeletal Both 0.7586 1.01 0.961,1.06 1854 17778 0.9661 0.999 0.951,1.05 1759 17372
741.4 Joint effusions musculoskeletal Both 0.7907 1.01 0.96,1.05 1930 19185 0.695 1.01 0.963,1.06 1893 18732
741.5 Hemarthrosis musculoskeletal Both 0.5129 1.09 0.841,1.41 64 640 0.4519 1.1 0.852,1.43 64 622
741.6 Villonodular synovitis musculoskeletal Both 0.3802 1.13 0.857,1.5 53 522 0.3981 1.13 0.853,1.49 53 510
742 Derangement of joint, non-traumatic musculoskeletal Both 0.2547 0.98 0.945,1.01 3462 27650 0.4018 0.984 0.948,1.02 3151 26276
742.1 Loose body in joint musculoskeletal Both 0.1656 0.878 0.731,1.06 131 1295 0.1589 0.875 0.726,1.05 128 1268
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.4519 0.95 0.832,1.09 243 2414 0.5047 0.955 0.836,1.09 240 2354
742.8 Articular cartilage disorder musculoskeletal Both 0.6902 1.03 0.887,1.2 191 1896 0.7096 1.03 0.885,1.2 189 1856
742.9 Other derangement of joint musculoskeletal Both 0.2729 0.98 0.944,1.02 3212 26883 0.4018 0.984 0.948,1.02 3151 26276
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.4603 1.01 0.984,1.04 7571 30458 0.4295 1.01 0.983,1.04 5598 28822
743.1 Osteoporosis musculoskeletal Both 0.8872 0.997 0.957,1.04 2982 15823 0.1072 1.12 0.976,1.28 224 2232
743.11 Osteoporosis NOS musculoskeletal Both 0.8492 0.996 0.956,1.04 2931 15630 0.9016 0.997 0.957,1.04 2857 15282
743.12 Senile osteoporosis musculoskeletal Both 0.7295 1.02 0.924,1.12 481 4333 0.7943 1.01 0.92,1.12 472 4240
743.13 Other specified osteoporosis musculoskeletal Both 0.0955 1.12 0.98,1.28 231 2290 0.1072 1.12 0.976,1.28 224 2232
743.2 Pathologic fracture musculoskeletal Both 0.07413 1.07 0.994,1.14 872 8504 0.0263 1.26 1.03,1.55 104 1117
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.3251 1.05 0.949,1.17 385 3799 0.2965 1.06 0.951,1.18 358 3703
743.22 Pathologic fracture of femur musculoskeletal Both 0.0195 1.26 1.04,1.53 116 1143 0.0263 1.26 1.03,1.55 104 1117
743.4 Stress fracture musculoskeletal Both 0.3334 0.942 0.834,1.06 291 2882 0.4027 0.949 0.839,1.07 285 2819
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.4539 1.01 0.982,1.04 5795 29464 0.4295 1.01 0.983,1.04 5598 28822
745 Pain in joint musculoskeletal Both 0.2168 0.987 0.967,1.01 15755 22596 0.2767 0.989 0.968,1.01 15449 21998
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.6209 1.01 0.964,1.06 1811 18049 0.2553 1.06 0.957,1.18 378 3929
747.1 Cardiac congenital anomalies congenital anomalies Both 0.8318 0.994 0.942,1.05 1446 14417 0.9016 1.01 0.901,1.13 332 3307
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.5408 1.03 0.94,1.13 519 5181 0.4198 1.04 0.948,1.14 500 5055
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.5623 0.976 0.9,1.06 632 6299 0.7447 0.986 0.908,1.07 618 6127
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.8222 1.01 0.907,1.13 342 3387 0.9016 1.01 0.901,1.13 332 3307
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.195 1.07 0.966,1.19 402 4014 0.2553 1.06 0.957,1.18 378 3929
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.9183 0.989 0.806,1.21 93 930 0.9506 1.01 0.817,1.24 90 910
749 Congenital anomalies of face and neck congenital anomalies Both 0.4808 0.966 0.878,1.06 455 4540 0.6808 0.953 0.757,1.2 77 878
749.1 Cleft palate congenital anomalies Both 0.3741 0.902 0.719,1.13 81 791 0.3698 0.901 0.719,1.13 81 778
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.7482 0.966 0.781,1.19 90 897 0.6808 0.953 0.757,1.2 77 878
750 Digestive congenital anomalies congenital anomalies Both 0.8185 1.01 0.935,1.09 739 7382 0.5768 1.05 0.895,1.22 178 1745
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.5902 0.968 0.861,1.09 307 3069 0.1086 0.8 0.609,1.05 57 553
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.4256 1.09 0.876,1.37 96 944 0.4603 1.09 0.869,1.36 94 920
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.5649 0.935 0.742,1.18 77 767 0.5521 0.932 0.739,1.18 76 748
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.228 1.12 0.932,1.35 121 1210 0.1683 1.14 0.946,1.37 118 1174
750.15 Congenital anomalies of stomach congenital anomalies Both 0.09772 0.793 0.603,1.04 57 567 0.1086 0.8 0.609,1.05 57 553
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.3917 1.04 0.946,1.15 438 4363 0.5768 1.05 0.895,1.22 178 1745
750.21 Congenital anomalies of intestine congenital anomalies Both 0.514 1.04 0.92,1.18 262 2613 0.5082 1.04 0.92,1.18 255 2556
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.6124 1.04 0.892,1.21 180 1790 0.5768 1.05 0.895,1.22 178 1745
751 Genitourinary congenital anomalies congenital anomalies Both 0.6839 0.99 0.941,1.04 1682 16764 0.06026 0.854 0.724,1.01 154 1529
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.2979 1.05 0.958,1.15 491 4897 0.2158 1.12 0.938,1.33 131 1267
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.4009 1.05 0.937,1.18 328 3280 0.3491 1.06 0.942,1.18 322 3204
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.1919 1.12 0.944,1.33 132 1301 0.2158 1.12 0.938,1.33 131 1267
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.6166 0.985 0.926,1.05 1139 11355 0.5689 0.963 0.847,1.1 247 2454
751.21 Cystic kidney disease congenital anomalies Both 0.8279 0.992 0.923,1.07 799 7929 0.9616 0.998 0.928,1.07 783 7758
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.7534 0.98 0.863,1.11 251 2506 0.5689 0.963 0.847,1.1 247 2454
751.3 Obstructive genitourinary defect congenital anomalies Both 0.07079 0.86 0.73,1.01 157 1560 0.06026 0.854 0.724,1.01 154 1529
752 Nervous system congenital anomalies congenital anomalies Both 0.9886 1.0 0.935,1.07 908 9073 0.01445 0.829 0.713,0.964 181 1966
752.1 Neural tube defects congenital anomalies Both 0.9795 0.999 0.927,1.08 728 7277 0.2972 0.912 0.768,1.08 138 1411
752.11 Spina bifida congenital anomalies Both 0.3342 0.92 0.777,1.09 144 1440 0.2972 0.912 0.768,1.08 138 1411
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.05623 0.871 0.755,1.0 201 2010 0.01445 0.829 0.713,0.964 181 1966
753 Congenital anomalies of the eye congenital anomalies Both 0.3296 1.09 0.917,1.29 146 1451 0.2198 1.12 0.937,1.33 139 1431
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.9683 0.999 0.937,1.06 1006 10049 0.2773 1.05 0.959,1.16 463 4553
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.2767 0.899 0.742,1.09 116 1155 0.3475 0.911 0.751,1.11 114 1126
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.2301 1.06 0.964,1.16 470 4675 0.2773 1.05 0.959,1.16 463 4553
755 Congenital anomalies of limbs congenital anomalies Both 0.7603 1.01 0.933,1.1 625 6237 0.5383 1.06 0.888,1.26 149 1491
755.1 Congenital deformities of feet congenital anomalies Both 0.8851 1.01 0.897,1.13 315 3138 0.9506 0.996 0.884,1.12 307 3072
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.6501 1.06 0.818,1.38 58 567 0.5916 1.08 0.824,1.4 57 551
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.4519 1.05 0.925,1.19 258 2580 0.5383 1.06 0.888,1.26 149 1491
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.5636 1.05 0.886,1.25 152 1520 0.5383 1.06 0.888,1.26 149 1491
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.5333 1.02 0.957,1.09 1021 10203 0.3873 1.03 0.958,1.12 713 7268
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.6152 1.07 0.815,1.41 55 527 0.561 1.09 0.823,1.43 55 512
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.4677 0.907 0.697,1.18 56 524 0.4842 0.91 0.699,1.18 56 513
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.3296 0.936 0.819,1.07 246 2459 0.3467 0.937 0.819,1.07 241 2408
756.5 Congenital osteodystrophies congenital anomalies Both 0.4406 1.03 0.955,1.11 743 7419 0.3873 1.03 0.958,1.12 713 7268
757 Congenital anomalies of the integument congenital anomalies Both 0.9441 1.0 0.888,1.14 283 2820 0.7798 1.02 0.899,1.15 280 2763
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.8147 0.979 0.822,1.17 134 1334 0.2685 0.885 0.712,1.1 84 885
758.1 Chromosomal anomalies congenital anomalies Both 0.4305 0.92 0.747,1.13 91 910 0.2685 0.885 0.712,1.1 84 885
759 Other and unspecified congenital anomalies congenital anomalies Both 0.5188 1.03 0.94,1.13 498 4964 0.04677 1.33 1.0,1.77 56 554
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.0631 1.31 0.986,1.74 57 567 0.04677 1.33 1.0,1.77 56 554
760 Back pain symptoms Both 0.2307 0.987 0.966,1.01 12687 25663 0.2275 0.987 0.966,1.01 12357 25090
761 Cervicalgia symptoms Both 0.5508 0.991 0.962,1.02 5134 32829 0.6457 0.993 0.964,1.02 4986 32084
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.7161 1.01 0.969,1.05 2927 27356 0.673 1.01 0.97,1.05 2868 26699
764 Sciatica symptoms Both 0.2254 1.03 0.985,1.07 2623 25291 0.2143 1.03 0.985,1.07 2583 24672
765 Cervical radiculitis symptoms Both 0.6668 0.988 0.935,1.04 1401 13966 0.7063 0.989 0.936,1.05 1377 13634
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.4808 0.988 0.956,1.02 4004 31031 0.5105 0.989 0.956,1.02 3906 30293
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.3681 0.901 0.719,1.13 85 835 0.4375 0.914 0.727,1.15 83 819
769 Nonallopathic lesions NEC symptoms Both 0.03981 0.931 0.87,0.997 923 9183 0.07586 0.939 0.877,1.01 901 8971
770 Myalgia and myositis unspecified symptoms Both 0.7674 0.995 0.964,1.03 4324 27592 0.929 1.0 0.969,1.03 4223 26944
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.5164 1.01 0.977,1.05 3638 29710 0.8531 1.01 0.936,1.08 776 7700
771.1 Swelling of limb symptoms Both 0.3581 1.01 0.983,1.05 4511 29862 0.3999 1.01 0.982,1.05 4356 29255
771.2 Cramp of limb symptoms Both 0.8166 1.01 0.938,1.08 791 7856 0.8531 1.01 0.936,1.08 776 7700
772 Symptoms of the muscles symptoms Both 0.7194 0.99 0.94,1.04 1549 15345 0.6471 1.03 0.916,1.15 311 3681
772.1 Muscular wasting and disuse atrophy symptoms Both 0.6745 0.975 0.867,1.1 320 3187 0.7063 0.977 0.868,1.1 312 3131
772.2 Spasm of muscle symptoms Both 0.5188 1.02 0.968,1.07 1780 17782 0.5321 1.02 0.967,1.07 1733 17443
772.3 Muscle weakness symptoms Both 0.2931 1.02 0.981,1.07 2339 22770 0.4027 1.02 0.975,1.06 2191 22306
772.4 Rhabdomyolysis symptoms Both 0.3715 0.916 0.755,1.11 117 1170 0.2133 0.878 0.716,1.08 106 1141
772.6 Facial weakness symptoms Both 0.2399 1.06 0.959,1.18 377 3746 0.6471 1.03 0.916,1.15 311 3681
773 Pain in limb symptoms Both 0.2924 1.01 0.99,1.03 11393 26958 0.3041 1.01 0.989,1.03 11126 26321
780 Hypothermia/Chills symptoms Both 0.3715 0.948 0.843,1.07 307 3069 0.7603 0.981 0.87,1.11 287 2994
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 1.0 1.0 0.952,1.05 1767 17206 0.4335 0.919 0.745,1.13 90 874
781.1 Loss of height symptoms Both 0.5284 0.935 0.759,1.15 91 890 0.4335 0.919 0.745,1.13 90 874
782.3 Edema symptoms Both 0.08511 1.03 0.996,1.06 4591 30849 0.1531 1.02 0.991,1.06 4425 30161
782.6 Pallor and flushing symptoms Both 0.9506 1.0 0.927,1.08 679 6769 0.9572 0.998 0.922,1.08 664 6631
783 Fever of unknown origin symptoms Both 0.7311 1.01 0.975,1.04 4616 33703 0.4667 0.951 0.832,1.09 238 2429
783.1 Postprocedural fever symptoms Both 0.5943 0.965 0.846,1.1 248 2473 0.4667 0.951 0.832,1.09 238 2429
785 Abdominal pain symptoms Both 0.1445 0.984 0.964,1.01 13257 25098 0.1227 0.983 0.962,1.0 12977 24474
788 Syncope and collapse symptoms Both 0.6982 0.993 0.956,1.03 3017 29114 0.6577 0.991 0.954,1.03 2926 28438
789 Nausea and vomiting symptoms Both 0.8892 0.998 0.974,1.02 8497 29838 0.8995 1.01 0.925,1.09 608 6222
789.1 Persistent vomiting symptoms Both 0.9661 1.0 0.923,1.09 634 6330 0.8995 1.01 0.925,1.09 608 6222
790 Nonspecific findings on examination of blood symptoms Both 0.4786 1.02 0.969,1.07 1740 17356 0.1403 1.15 0.955,1.39 118 1198
790.1 Elevated sedimentation rate symptoms Both 0.2871 0.916 0.778,1.08 158 1580 0.3119 0.919 0.78,1.08 155 1546
790.6 Other abnormal blood chemistry symptoms Both 0.2234 1.02 0.989,1.05 4849 31554 0.2518 1.02 0.987,1.05 4707 30831
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.5383 0.956 0.827,1.1 204 2026 0.5929 0.961 0.832,1.11 204 1976
790.9 Abnormal arterial blood gases symptoms Both 0.1702 1.14 0.947,1.36 123 1230 0.1403 1.15 0.955,1.39 118 1198
791 Gangrene symptoms Both 0.6281 1.03 0.902,1.19 212 2104 0.6471 1.03 0.899,1.19 211 2057
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.1285 0.965 0.921,1.01 2171 11972 0.227 0.957 0.89,1.03 832 7621
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.1567 0.95 0.884,1.02 841 7806 0.227 0.957 0.89,1.03 832 7621
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.2897 1.05 0.962,1.14 588 5848 0.9016 1.0 0.953,1.06 1613 16208
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.877 1.0 0.955,1.06 1661 16601 0.9016 1.0 0.953,1.06 1613 16208
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.6471 1.02 0.928,1.13 433 4330 0.4266 1.04 0.943,1.15 419 4219
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.1734 1.04 0.985,1.09 1632 15619 0.9705 0.997 0.847,1.17 155 1615
795.8 Abnormal tumor markers symptoms Both 0.5861 0.986 0.937,1.04 1698 13664 0.9705 0.997 0.847,1.17 155 1615
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.8414 1.02 0.869,1.19 167 1662 0.9705 0.997 0.847,1.17 155 1615
796 Elevated prostate specific antigen [PSA] symptoms Male 0.1626 0.963 0.913,1.02 1700 8294 0.1782 0.964 0.914,1.02 1671 8086
797 Shock symptoms Both 0.6516 1.02 0.928,1.13 445 4446 0.3508 0.929 0.797,1.08 178 1777
797.1 Cardiogenic shock symptoms Both 0.4198 0.939 0.807,1.09 183 1822 0.3508 0.929 0.797,1.08 178 1777
798 Malaise and fatigue symptoms Both 0.8299 1.0 0.979,1.03 8867 29476 0.514 0.981 0.927,1.04 1298 13150
798.1 Chronic fatigue syndrome symptoms Both 0.3622 0.974 0.921,1.03 1349 13380 0.514 0.981 0.927,1.04 1298 13150
799 Debility unspecified symptoms Both 0.02138 1.06 1.01,1.12 1672 16007 0.03981 1.06 1.0,1.11 1562 15677
800 Fracture of lower limb injuries & poisonings Both 0.865 1.0 0.958,1.05 1879 18684 0.2917 0.937 0.831,1.06 289 2820
800.1 Fracture of neck of femur injuries & poisonings Both 0.6295 1.03 0.926,1.14 409 4028 0.8279 1.01 0.912,1.12 399 3937
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.2729 0.951 0.869,1.04 539 5364 0.1824 0.94 0.859,1.03 528 5237
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.6501 0.983 0.911,1.06 744 7420 0.5546 0.977 0.905,1.05 734 7252
800.4 Fracture of patella injuries & poisonings Both 0.3296 0.942 0.836,1.06 293 2904 0.2917 0.937 0.831,1.06 289 2820
801 Fracture of ankle and foot injuries & poisonings Both 0.6934 1.01 0.962,1.06 1804 17960 0.5321 1.02 0.954,1.09 895 8901
801.1 Fracture of foot injuries & poisonings Both 0.4018 1.03 0.962,1.1 913 9098 0.5321 1.02 0.954,1.09 895 8901
802 Fracture of pelvis injuries & poisonings Both 0.3206 0.943 0.841,1.06 321 3192 0.2786 0.938 0.835,1.05 315 3118
803 Fracture of upper limb injuries & poisonings Both 0.9683 1.0 0.952,1.05 1644 16288 0.6427 0.976 0.882,1.08 415 4080
803.1 Fracture of humerus injuries & poisonings Both 0.9462 1.0 0.922,1.09 592 5913 0.955 0.998 0.916,1.09 583 5771
803.2 Fracture of radius and ulna injuries & poisonings Both 0.4055 0.971 0.907,1.04 899 8929 0.7161 0.976 0.854,1.11 245 2422
803.21 Colles' fracture injuries & poisonings Both 0.7194 0.976 0.856,1.11 248 2475 0.7161 0.976 0.854,1.11 245 2422
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.673 0.979 0.885,1.08 419 4190 0.6427 0.976 0.882,1.08 415 4080
804 Fracture of hand or wrist injuries & poisonings Both 0.857 0.995 0.938,1.05 1272 12504 0.9484 0.998 0.941,1.06 1248 12207
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.05248 0.94 0.883,1.0 1082 10755 0.06026 0.941 0.882,1.0 1047 10513
807 Fracture of ribs injuries & poisonings Both 0.4236 0.964 0.882,1.05 543 5428 0.5483 0.973 0.889,1.06 529 5296
809 Fracture of unspecified bones injuries & poisonings Both 0.6501 1.01 0.968,1.05 2426 23282 0.8035 1.01 0.964,1.05 2359 22741
817 Concussion injuries & poisonings Both 0.2056 0.953 0.884,1.03 771 7696 0.15 0.946 0.876,1.02 752 7525
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.2679 1.07 0.946,1.22 240 2380 0.3733 1.1 0.89,1.37 82 816
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.8472 0.978 0.777,1.23 74 740 0.9311 0.99 0.781,1.25 69 724
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.5521 1.07 0.863,1.32 84 837 0.3733 1.1 0.89,1.37 82 816
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.1211 0.962 0.916,1.01 1782 17605 0.1064 0.96 0.913,1.01 1730 17203
830 Dislocation injuries & poisonings Both 0.3451 0.982 0.947,1.02 3129 28682 0.4236 0.985 0.949,1.02 3084 27959
835 Internal derangement of knee injuries & poisonings Both 0.2089 0.969 0.923,1.02 1774 17453 0.2312 0.97 0.923,1.02 1753 17022
836 Traumatic arthropathy injuries & poisonings Both 0.3491 0.953 0.862,1.05 423 4213 0.3334 0.951 0.86,1.05 421 4115
840 Sprains and strains injuries & poisonings Both 0.2773 0.985 0.958,1.01 6106 31582 0.8072 0.995 0.952,1.04 2229 19033
840.1 Muscle/tendon sprain injuries & poisonings Both 0.5781 1.03 0.932,1.14 429 4269 0.4742 1.04 0.938,1.15 421 4146
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.5117 1.02 0.964,1.08 1343 13394 0.471 1.02 0.965,1.08 1323 13039
840.3 Joint/ligament sprain injuries & poisonings Both 0.7161 0.992 0.949,1.04 2261 19530 0.8072 0.995 0.952,1.04 2229 19033
841 Sprains and strains of back and neck injuries & poisonings Both 0.07586 0.947 0.892,1.01 1175 11729 0.09333 0.95 0.894,1.01 1152 11425
842 Other sprains and strains injuries & poisonings Both 0.123 1.05 0.987,1.12 1079 10729 0.139 1.05 0.985,1.12 1065 10460
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.2636 0.973 0.927,1.02 1807 18037 0.2037 0.968 0.922,1.02 1733 17646
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.4699 1.03 0.955,1.1 797 7958 0.3758 1.03 0.961,1.11 781 7786
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.5888 1.03 0.929,1.14 398 3977 0.6871 1.02 0.921,1.13 390 3883
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.6902 1.01 0.959,1.06 1537 15333 0.8375 1.01 0.954,1.06 1492 15009
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 1.0 1.0 0.878,1.14 254 2540 0.787 1.02 0.889,1.17 227 2491
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.3767 0.945 0.834,1.07 262 2617 0.3508 0.94 0.825,1.07 240 2555
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.5649 0.983 0.926,1.04 1196 11925 0.5781 0.983 0.926,1.04 1175 11675
858 Complication of internal orthopedic device injuries & poisonings Both 0.873 0.996 0.95,1.04 1892 18846 0.9441 1.0 0.955,1.05 1843 18441
859 Complication due to other implant and internal device injuries & poisonings Both 0.2679 0.973 0.927,1.02 1820 18191 0.2698 0.973 0.926,1.02 1744 17792
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.5598 0.989 0.955,1.03 3389 30552 0.7568 0.971 0.804,1.17 117 1144
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.6486 1.04 0.881,1.23 156 1551 0.7925 1.02 0.865,1.21 151 1503
870.2 Open wound of ear injuries & poisonings Both 0.3155 1.1 0.912,1.33 114 1131 0.3573 1.09 0.903,1.33 111 1108
870.3 Other open wound of head and face injuries & poisonings Both 0.4295 1.03 0.963,1.09 1064 10560 0.5768 1.02 0.955,1.09 1025 10312
870.4 Open wound of nose and sinus injuries & poisonings Both 0.4009 0.936 0.801,1.09 168 1667 0.4786 0.945 0.808,1.11 165 1637
870.5 Open wound of lip and mouth injuries & poisonings Both 0.7311 1.02 0.895,1.17 230 2293 0.9099 1.01 0.878,1.16 223 2238
870.6 Open wound of neck injuries & poisonings Both 0.06761 0.866 0.742,1.01 184 1833 0.1 0.876 0.748,1.03 176 1786
870.8 Open wound of genital organs injuries & poisonings Both 0.7499 0.97 0.804,1.17 117 1170 0.7568 0.971 0.804,1.17 117 1144
871 Open wounds of extremities injuries & poisonings Both 0.7727 0.994 0.955,1.03 2705 26585 0.4102 1.06 0.918,1.23 191 1865
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.1062 1.09 0.983,1.2 438 4378 0.1633 1.07 0.971,1.19 425 4264
871.2 Open wound of finger(s) injuries & poisonings Both 0.3162 0.962 0.891,1.04 731 7291 0.2897 0.959 0.888,1.04 719 7096
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.2793 0.94 0.841,1.05 331 3277 0.2748 0.939 0.838,1.05 324 3208
871.4 Open wound of toe(s) injuries & poisonings Both 0.4207 1.06 0.917,1.23 191 1901 0.4102 1.06 0.918,1.23 191 1865
872 Traumatic amputation injuries & poisonings Both 0.8453 0.99 0.896,1.09 415 4129 0.8492 0.99 0.896,1.1 412 4024
873 Broken tooth injuries & poisonings Both 0.13 1.14 0.963,1.34 148 1471 0.3917 1.08 0.908,1.28 141 1438
874 Complication of amputation stump injuries & poisonings Both 0.7244 0.966 0.796,1.17 122 1220 0.695 0.961 0.79,1.17 120 1187
875 Non-healing surgical wound injuries & poisonings Both 0.6998 0.982 0.895,1.08 495 4950 0.3388 0.955 0.869,1.05 473 4827
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.9078 0.995 0.918,1.08 669 6680 0.7551 0.987 0.909,1.07 646 6528
907 Injuries to the nervous system injuries & poisonings Both 0.7278 0.988 0.922,1.06 888 8852 0.7464 0.988 0.922,1.06 858 8636
910 Superficial injury, infected injuries & poisonings Both 0.1496 1.18 0.942,1.48 89 887 0.1377 1.19 0.946,1.49 87 863
911 Blister injuries & poisonings Both 0.873 1.01 0.869,1.18 185 1838 0.8035 1.02 0.873,1.19 179 1799
912 Insect bite injuries & poisonings Both 0.869 1.01 0.902,1.13 321 3207 0.879 1.01 0.9,1.13 316 3140
913 Toxic effect of venom injuries & poisonings Both 0.9354 0.995 0.874,1.13 247 2461 0.9572 1.0 0.881,1.14 243 2407
915 Superficial injury without mention of infection injuries & poisonings Both 0.369 1.02 0.977,1.06 2368 23457 0.3873 1.02 0.976,1.06 2295 22911
916 Contusion injuries & poisonings Both 0.6026 0.99 0.955,1.03 3199 30228 0.4603 0.986 0.95,1.02 3113 29510
930 Allergic reaction to food injuries & poisonings Both 0.005623 1.13 1.04,1.22 597 5953 0.007586 1.12 1.03,1.22 580 5839
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.2761 1.05 0.962,1.15 530 5290 0.3811 1.04 0.952,1.14 518 5177
938 Dermatitis due to solar radiation injuries & poisonings Both 0.4519 1.01 0.98,1.05 4197 24407 0.3681 1.02 0.982,1.05 3906 23448
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.3334 0.924 0.787,1.08 164 1640 0.2999 0.918 0.781,1.08 161 1594
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.415 1.01 0.981,1.05 4001 24007 0.3681 1.02 0.982,1.05 3906 23448
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.8017 1.02 0.862,1.21 140 1400 0.8299 1.02 0.859,1.21 139 1364
942 Infusion and transfusion reaction injuries & poisonings Both 0.4842 0.952 0.829,1.09 221 2205 0.4295 0.945 0.822,1.09 216 2142
946 Anaphylactic shock NOS injuries & poisonings Both 0.7211 0.981 0.884,1.09 385 3830 0.8241 0.988 0.889,1.1 377 3734
947 Urticaria injuries & poisonings Both 0.5689 1.02 0.952,1.09 889 8845 0.6109 1.02 0.949,1.09 866 8653
949 Allergies, other injuries & poisonings Both 0.1892 1.02 0.99,1.05 5269 26807 0.2234 1.02 0.989,1.05 5122 26191
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.3483 0.953 0.863,1.05 419 4176 0.6412 0.976 0.881,1.08 396 4073
957 Injury to other and unspecified nerves injuries & poisonings Both 0.3917 0.916 0.75,1.12 116 1150 0.4603 0.927 0.758,1.13 115 1130
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.1371 0.953 0.895,1.02 1073 10721 0.5728 0.941 0.761,1.16 90 889
958.1 Postoperative shock injuries & poisonings Both 0.3041 0.912 0.765,1.09 133 1325 0.2754 0.906 0.758,1.08 131 1293
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.5821 0.943 0.764,1.16 92 911 0.5728 0.941 0.761,1.16 90 889
960 Poisoning by antibiotics injuries & poisonings Both 0.9528 0.999 0.955,1.04 2108 18753 0.955 0.998 0.944,1.06 1344 13630
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.1274 1.13 0.965,1.33 158 1552 0.1153 1.14 0.968,1.34 151 1533
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.9376 0.998 0.945,1.05 1414 13864 0.955 0.998 0.944,1.06 1344 13630
961 Poisoning by other anti-infectives injuries & poisonings Both 0.6252 1.02 0.931,1.13 470 4694 0.26 1.04 0.971,1.11 899 9047
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.2805 1.04 0.97,1.11 939 9190 0.26 1.04 0.971,1.11 899 9047
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.5623 1.03 0.941,1.12 561 5601 0.9863 0.999 0.882,1.13 261 2975
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.7031 1.02 0.911,1.15 308 3069 0.875 1.01 0.894,1.14 274 3021
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.7568 1.02 0.907,1.14 305 3029 0.9863 0.999 0.882,1.13 261 2975
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.52 1.02 0.97,1.06 2031 19919 0.778 0.993 0.946,1.04 1781 19195
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.399 1.02 0.974,1.07 1980 19507 0.778 0.993 0.946,1.04 1781 19195
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.3532 1.04 0.955,1.14 538 5360 0.5781 1.03 0.936,1.13 490 4988
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.3499 1.04 0.954,1.14 509 5070 0.5781 1.03 0.936,1.13 490 4988
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.9863 1.0 0.928,1.08 753 7525 0.2427 0.88 0.709,1.09 97 953
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.5572 0.983 0.928,1.04 1305 12848 0.5 0.98 0.924,1.04 1233 12640
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.3296 0.899 0.726,1.11 98 967 0.2427 0.88 0.709,1.09 97 953
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.5212 1.08 0.86,1.35 86 850 0.879 1.02 0.806,1.29 79 835
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.5117 1.02 0.958,1.09 1000 9986 0.4875 1.02 0.958,1.09 967 9826
969 Poisoning by psychotropic agents injuries & poisonings Both 0.9226 0.993 0.87,1.13 234 2331 0.7638 0.98 0.856,1.12 226 2294
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.6776 1.06 0.811,1.38 56 546 0.7413 1.05 0.8,1.37 55 537
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.9333 0.994 0.872,1.13 228 2269 0.1837 1.16 0.931,1.45 82 850
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.1 1.23 0.961,1.58 66 637 0.06607 1.27 0.985,1.63 63 625
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.2455 1.14 0.916,1.41 86 860 0.1837 1.16 0.931,1.45 82 850
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.6281 1.05 0.853,1.3 90 896 0.7396 1.04 0.836,1.29 88 879
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.7278 0.958 0.751,1.22 69 686 0.7328 0.958 0.75,1.22 67 675
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.03388 0.743 0.565,0.977 60 600 0.02818 0.731 0.553,0.967 58 592
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.507 1.02 0.966,1.07 1565 14843 0.6281 1.01 0.961,1.07 1497 14614
979 Adverse drug events and drug allergies injuries & poisonings Both 0.826 1.01 0.961,1.05 2116 20636 0.7278 1.01 0.963,1.06 2026 20287
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.1694 1.16 0.94,1.42 91 904 0.1368 1.17 0.951,1.44 89 878
990 Effects radiation NOS injuries & poisonings Both 0.861 1.0 0.964,1.04 2707 23906 0.9183 1.0 0.961,1.04 2454 23485
994 Sepsis and SIRS injuries & poisonings Both 0.4121 0.979 0.932,1.03 1724 17160 0.4266 0.962 0.875,1.06 467 4724
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.6546 1.03 0.904,1.17 248 2472 0.7998 1.02 0.891,1.16 241 2420
994.2 Sepsis injuries & poisonings Both 0.4285 0.98 0.931,1.03 1636 16281 0.4266 0.962 0.875,1.06 467 4724
994.21 Septic shock injuries & poisonings Both 0.5 0.968 0.882,1.06 484 4840 0.4266 0.962 0.875,1.06 467 4724
1000 Burns injuries & poisonings Both 0.413 0.966 0.891,1.05 638 6350 0.3707 0.963 0.887,1.05 627 6201
1001 Foreign body injury injuries & poisonings Both 0.2748 1.02 0.982,1.07 2372 22762 0.2099 1.03 0.985,1.07 2284 22221
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.5176 0.99 0.96,1.02 4830 32603 0.6152 0.992 0.962,1.02 4648 31892
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.9977 1.0 0.941,1.06 1136 11344 0.8054 0.992 0.932,1.06 1091 11060
1005 Other symptoms injuries & poisonings Both 0.6209 1.01 0.981,1.03 7724 30626 0.6761 1.01 0.98,1.03 7397 30049
1006 Crushing injury injuries & poisonings Both 0.8433 0.987 0.867,1.12 245 2437 0.9886 0.999 0.877,1.14 243 2380
1007 Injury to blood vessels injuries & poisonings Both 0.2014 0.936 0.845,1.04 411 4106 0.2193 0.937 0.845,1.04 400 3990
1008 Crushing or internal injury to organs injuries & poisonings Both 0.2891 0.964 0.901,1.03 934 9331 0.3304 0.967 0.902,1.04 907 9123
1009 Injury, NOS injuries & poisonings Both 0.8241 1.0 0.979,1.03 9284 29063 0.6561 1.01 0.982,1.03 9081 28362
1010 Other tests injuries & poisonings Both 0.6653 1.0 0.984,1.02 19027 19331 0.8472 1.0 0.982,1.02 18538 18916
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.6998 0.995 0.967,1.02 5922 32336 0.8054 0.996 0.969,1.03 5692 31662
1012 Late effect injuries & poisonings Both 0.5093 1.02 0.953,1.1 792 7909 0.6324 1.02 0.946,1.1 771 7714
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.8453 0.996 0.955,1.04 2459 23709 0.9908 1.0 0.958,1.04 2355 23154
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3972 1.07 0.915,1.25 177 1770 0.5383 1.05 0.895,1.24 167 1737
1015 Effects of other external causes injuries & poisonings Both 0.5248 1.01 0.981,1.04 5744 32595 0.7834 1.0 0.976,1.03 5537 31898
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.00123 1.07 1.03,1.12 2208 21537 0.004571 1.07 1.02,1.12 2083 21041
1100 Family history injuries & poisonings Both 0.3342 0.934 0.814,1.07 222 2220 0.2438 0.92 0.799,1.06 216 2178
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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