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MGI PRS for Malignant neoplasm of testis(187.2) based on UKB GWAS (PHESANT)
GWAS reference: !UKB_GWAS GWAS source: UKB GWAS (PHESANT) PRS method: P_5e-08
PRSweb LD reference: UKB GWAS phenotype: Cancer code, self-reported: testicular cancer PRSweb date: 2020-06-20
GWAS ID: 20001_1045 GWAS URL: http://www.nealelab.is/uk-biobank Genome build: GRCh37/hg19
PRS tuning parameter: P<=5e-08 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.1549 1.03 0.988,1.08 2317 23065 0.2512 1.04 0.972,1.11 927 9257
008.5 Bacterial enteritis infectious diseases Both 0.01905 1.08 1.01,1.15 1090 10875 0.06761 1.07 0.995,1.15 891 8875
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.05888 1.07 0.998,1.15 896 8939 0.06761 1.07 0.995,1.15 891 8875
008.6 Viral Enteritis infectious diseases Both 0.2917 1.05 0.961,1.14 590 5900 0.2786 1.05 0.962,1.14 587 5872
010 Tuberculosis infectious diseases Both 0.9462 0.995 0.858,1.15 195 1948 0.3681 1.01 0.989,1.03 18874 19208
031 Diseases due to other mycobacteria infectious diseases Both 0.006761 1.41 1.1,1.81 73 722 0.006761 1.41 1.1,1.81 73 719
038 Septicemia infectious diseases Both 0.5888 0.988 0.944,1.03 2043 20052 0.4467 0.974 0.911,1.04 949 9401
038.1 Gram negative septicemia infectious diseases Both 0.2877 0.95 0.864,1.04 459 4559 0.2254 0.943 0.858,1.04 457 4513
038.2 Gram positive septicemia infectious diseases Both 0.9506 1.0 0.865,1.17 184 1840 0.8892 0.989 0.85,1.15 180 1823
038.3 Bacteremia infectious diseases Both 0.4764 0.976 0.913,1.04 955 9489 0.4467 0.974 0.911,1.04 949 9401
041 Bacterial infection NOS infectious diseases Both 0.118 0.976 0.946,1.01 4641 32299 0.2371 0.923 0.807,1.05 226 2249
041.1 Staphylococcus infections infectious diseases Both 0.9977 1.0 0.947,1.06 1390 13828 0.4943 1.03 0.948,1.12 632 6323
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.867 0.993 0.92,1.07 714 7071 0.8492 0.993 0.919,1.07 702 7009
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.5728 1.02 0.944,1.11 639 6376 0.4943 1.03 0.948,1.12 632 6323
041.2 Streptococcus infection infectious diseases Both 0.5395 0.982 0.929,1.04 1316 13131 0.6823 0.971 0.843,1.12 203 2032
041.21 Rheumatic fever / chorea infectious diseases Both 0.5768 0.961 0.835,1.11 205 2047 0.6823 0.971 0.843,1.12 203 2032
041.4 E. coli infectious diseases Both 0.4613 1.03 0.959,1.1 949 9462 0.4808 1.02 0.958,1.1 944 9403
041.8 H. pylori infectious diseases Both 0.1148 1.13 0.971,1.31 190 1892 0.1189 1.13 0.97,1.31 188 1882
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.2612 0.927 0.811,1.06 228 2265 0.2371 0.923 0.807,1.05 226 2249
053 Herpes zoster infectious diseases Both 0.4966 1.02 0.962,1.08 1184 11746 0.2825 1.09 0.929,1.29 165 1644
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.2301 1.1 0.939,1.3 166 1655 0.2825 1.09 0.929,1.29 165 1644
054 Herpes simplex infectious diseases Both 0.3483 1.03 0.97,1.09 1235 12278 0.3184 1.03 0.971,1.09 1225 12228
070 Viral hepatitis infectious diseases Both 0.9016 0.995 0.918,1.08 661 6584 0.6607 1.02 0.948,1.09 914 9172
070.1 Viral hepatitis A infectious diseases Both 0.9908 1.0 0.779,1.29 67 660 0.9977 1.0 0.776,1.29 66 660
070.2 Viral hepatitis B infectious diseases Both 0.13 0.887 0.759,1.04 162 1620 0.1213 0.884 0.756,1.03 162 1607
070.3 Viral hepatitis C infectious diseases Both 0.7691 1.02 0.919,1.12 439 4366 0.8851 1.01 0.911,1.11 435 4335
070.4 Chronic hepatitis infectious diseases Both 0.9886 0.999 0.852,1.17 161 1610 0.8433 1.02 0.865,1.19 157 1601
070.9 Hepatitis NOS infectious diseases Both 0.6966 1.01 0.947,1.08 924 9231 0.6607 1.02 0.948,1.09 914 9172
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.3631 0.917 0.762,1.1 122 1220 0.2825 0.892 0.724,1.1 93 941
071.1 HIV infection, symptomatic infectious diseases Both 0.3365 0.904 0.735,1.11 95 950 0.2825 0.892 0.724,1.1 93 941
078 Viral warts & HPV infectious diseases Both 0.3334 1.02 0.98,1.06 2651 24185 0.3483 1.02 0.979,1.06 2627 24050
079 Viral infection infectious diseases Both 0.9506 0.999 0.97,1.03 5061 29504 0.6714 0.982 0.901,1.07 577 5677
079.1 Varicella infection infectious diseases Both 0.9484 1.0 0.964,1.04 2940 25647 0.9397 0.999 0.961,1.04 2911 25495
079.2 Infectious mononucleosis infectious diseases Both 0.2104 0.915 0.796,1.05 213 2093 0.1413 0.9 0.783,1.04 210 2083
079.9 Viremia, NOS infectious diseases Both 0.673 0.982 0.901,1.07 579 5713 0.6714 0.982 0.901,1.07 577 5677
080 Postoperative infection infectious diseases Both 0.1932 0.973 0.935,1.01 2586 25769 0.1945 0.973 0.934,1.01 2554 25610
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.1726 0.962 0.911,1.02 1364 13616 0.2037 0.965 0.913,1.02 1357 13522
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.5585 1.02 0.946,1.11 700 6990 0.5035 1.03 0.949,1.11 694 6963
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.6053 1.01 0.97,1.05 2379 23308 0.1991 0.914 0.797,1.05 219 2206
110.1 Dermatophytosis infectious diseases Both 0.6039 1.01 0.968,1.06 2164 21163 0.4102 0.965 0.886,1.05 564 5633
110.11 Dermatophytosis of nail infectious diseases Both 0.8551 1.01 0.949,1.06 1264 12489 0.8318 1.01 0.95,1.07 1254 12390
110.12 Althete's foot infectious diseases Both 0.2393 1.05 0.967,1.14 593 5884 0.2099 1.06 0.97,1.15 589 5829
110.13 Dermatophytosis of the body infectious diseases Both 0.4634 0.969 0.89,1.05 570 5682 0.4102 0.965 0.886,1.05 564 5633
110.2 Dermatomycoses infectious diseases Both 0.7228 0.978 0.866,1.1 283 2812 0.7745 0.982 0.87,1.11 282 2797
112 Candidiasis infectious diseases Both 0.8318 0.996 0.958,1.03 2931 25310 0.2249 1.06 0.966,1.16 542 5430
112.3 Candidiasis of skin and nails infectious diseases Both 0.2506 1.05 0.963,1.15 546 5450 0.2249 1.06 0.966,1.16 542 5430
117 Mycoses infectious diseases Both 0.5689 1.03 0.936,1.13 494 4925 0.2371 1.13 0.922,1.39 105 1034
117.1 Histoplasmosis infectious diseases Both 0.7798 1.04 0.806,1.33 66 660 0.6592 1.06 0.821,1.37 65 654
117.4 Aspergillosis infectious diseases Both 0.246 1.13 0.92,1.38 105 1045 0.2371 1.13 0.922,1.39 105 1034
130 Spirochetal infection infectious diseases Both 0.7499 0.97 0.805,1.17 118 1177 0.9863 1.0 0.807,1.24 86 856
130.1 Lyme disease infectious diseases Both 0.9705 1.0 0.808,1.25 86 860 0.9863 1.0 0.807,1.24 86 856
132 Infestation (lice, mites) infectious diseases Both 0.7031 1.03 0.87,1.23 146 1460 0.5636 1.05 0.884,1.25 145 1454
134 Helminthiases infectious diseases Both 0.6561 1.07 0.793,1.45 54 540 0.6561 1.07 0.794,1.44 54 537
136 Other infectious and parasitic diseases infectious diseases Both 0.8035 1.01 0.964,1.05 2438 24314 0.7962 1.01 0.964,1.05 2414 24159
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.1622 0.958 0.903,1.02 1166 11657 0.1932 0.961 0.905,1.02 1149 11544
145 Cancer of mouth neoplasms Both 0.236 0.965 0.909,1.02 1182 11759 0.02399 0.839 0.72,0.977 172 1704
145.1 Cancer of lip neoplasms Both 0.4943 1.09 0.848,1.41 69 690 0.4426 1.11 0.855,1.43 68 683
145.2 Cancer of tongue neoplasms Both 0.04365 0.916 0.841,0.998 550 5486 0.04677 0.917 0.841,0.999 546 5428
145.3 Cancer of major salivary glands neoplasms Both 0.257 1.07 0.95,1.21 310 3093 0.2265 1.08 0.955,1.22 308 3064
145.4 Cancer of the gums neoplasms Both 0.2761 0.911 0.77,1.08 143 1419 0.375 0.926 0.782,1.1 141 1411
145.5 Cancer of the mouth floor neoplasms Both 0.02692 0.842 0.723,0.98 173 1723 0.02399 0.839 0.72,0.977 172 1704
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 1.0 1.0 0.941,1.06 1124 11202 0.9162 1.01 0.874,1.16 205 2054
149.1 Cancer of oropharynx neoplasms Both 0.26 0.935 0.831,1.05 291 2892 0.2404 0.932 0.828,1.05 287 2862
149.2 Cancer of nasopharynx neoplasms Both 0.561 1.07 0.856,1.33 87 855 0.7907 1.03 0.825,1.29 85 853
149.3 Cancer of hypopharynx neoplasms Both 0.8035 1.03 0.808,1.32 68 680 0.9528 0.993 0.776,1.27 66 674
149.4 Cancer of larynx neoplasms Both 0.1435 1.09 0.971,1.22 332 3314 0.1837 1.08 0.963,1.21 325 3279
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.6918 0.982 0.897,1.07 505 5041 0.8166 0.989 0.903,1.08 497 4995
149.9 Cancer of of nasal cavities neoplasms Both 0.7568 1.02 0.887,1.18 208 2067 0.9162 1.01 0.874,1.16 205 2054
150 Cancer of esophagus neoplasms Both 0.5188 1.03 0.933,1.15 378 3776 0.6012 1.03 0.927,1.14 375 3738
151 Cancer of stomach neoplasms Both 0.1535 1.08 0.973,1.19 430 4292 0.1746 1.07 0.97,1.19 426 4256
153 Colorectal cancer neoplasms Both 0.151 1.04 0.984,1.11 1196 11882 0.9057 1.0 0.928,1.09 659 6611
153.2 Colon cancer neoplasms Both 0.04365 1.07 1.0,1.15 941 9327 0.04898 1.07 1.0,1.15 931 9254
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.8872 1.01 0.93,1.09 669 6663 0.9057 1.0 0.928,1.09 659 6611
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.26 0.944 0.855,1.04 418 4180 0.03388 0.879 0.78,0.99 280 2825
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.0389 0.883 0.785,0.994 285 2850 0.03388 0.879 0.78,0.99 280 2825
157 Pancreatic cancer neoplasms Both 0.03548 1.11 1.01,1.23 430 4292 0.02818 1.12 1.01,1.24 425 4264
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.3097 1.03 0.973,1.09 1369 13455 0.414 1.02 0.968,1.08 1356 13358
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.7852 1.01 0.939,1.09 779 7785 0.7568 0.98 0.861,1.12 247 2545
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.6918 1.03 0.886,1.2 183 1830 0.6166 1.04 0.893,1.21 181 1814
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.4831 1.07 0.892,1.27 133 1330 0.4831 1.07 0.892,1.27 132 1315
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.673 0.973 0.857,1.11 255 2550 0.7568 0.98 0.861,1.12 247 2545
164 Cancer of intrathoracic organs neoplasms Both 0.6471 1.05 0.857,1.28 111 1110 0.6368 1.05 0.859,1.28 111 1105
165 Cancer within the respiratory system neoplasms Both 0.877 0.995 0.931,1.06 945 9436 0.7834 0.99 0.923,1.06 857 8645
165.1 Cancer of bronchus; lung neoplasms Both 0.7762 0.99 0.924,1.06 874 8724 0.7834 0.99 0.923,1.06 857 8645
170 Cancer of bone and connective tissue neoplasms Both 0.9484 0.998 0.947,1.05 1538 15304 0.1396 0.954 0.897,1.02 1073 10847
170.1 Bone cancer neoplasms Both 0.7516 1.01 0.935,1.1 668 6660 0.7211 1.01 0.936,1.1 658 6612
170.2 Cancer of connective tissue neoplasms Both 0.1358 0.954 0.897,1.01 1097 10941 0.1396 0.954 0.897,1.02 1073 10847
172 Skin cancer neoplasms Both 0.3388 0.987 0.961,1.01 7099 27878 0.3855 1.03 0.967,1.09 1193 10218
172.1 Melanomas of skin, dx or hx neoplasms Both 0.7586 1.01 0.967,1.05 2701 21867 0.4571 1.02 0.975,1.06 2602 21384
172.11 Melanomas of skin neoplasms Both 0.4345 1.02 0.976,1.06 2624 21526 0.4571 1.02 0.975,1.06 2602 21384
172.2 Other non-epithelial cancer of skin neoplasms Both 0.2355 0.982 0.954,1.01 5888 25669 0.2489 0.972 0.927,1.02 1888 14469
172.21 Basal cell carcinoma neoplasms Both 0.04169 0.96 0.924,0.998 2988 20068 0.04786 0.961 0.924,1.0 2961 19945
172.22 Squamous cell carcinoma neoplasms Both 0.2523 0.973 0.927,1.02 1917 14585 0.2489 0.972 0.927,1.02 1888 14469
172.3 Carcinoma in situ of skin neoplasms Both 0.3381 1.03 0.97,1.09 1215 10290 0.3855 1.03 0.967,1.09 1193 10218
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.03548 0.946 0.898,0.996 1575 15093 0.02089 0.94 0.893,0.991 1559 15011
174 Breast cancer neoplasms Both 0.1667 0.97 0.93,1.01 2694 13131 0.3083 1.08 0.933,1.25 205 2050
174.1 Breast cancer [female] neoplasms Female 0.1189 0.966 0.925,1.01 2605 12548 0.139 0.968 0.926,1.01 2565 12510
174.11 Malignant neoplasm of female breast neoplasms Female 0.139 0.968 0.926,1.01 2565 12510 0.139 0.968 0.926,1.01 2565 12510
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.3556 1.07 0.927,1.24 206 2051 0.3083 1.08 0.933,1.25 205 2050
175 Acquired absence of breast neoplasms Female 0.9462 1.0 0.937,1.07 978 9172 0.9462 1.0 0.937,1.07 978 9172
180 Cervical cancer and dysplasia neoplasms Female 0.9397 1.0 0.943,1.07 1182 10494 0.5082 0.976 0.909,1.05 857 7886
180.1 Cervical cancer neoplasms Female 0.1125 1.09 0.981,1.21 430 4300 0.1125 1.09 0.981,1.21 430 4300
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.5082 0.976 0.909,1.05 857 7886 0.5082 0.976 0.909,1.05 857 7886
182 Malignant neoplasm of uterus neoplasms Female 0.9226 0.996 0.917,1.08 643 6390 0.9226 0.996 0.917,1.08 643 6390
184 Cancer of other female genital organs neoplasms Female 0.2427 0.959 0.895,1.03 910 8957 0.4898 0.968 0.883,1.06 526 5253
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.2655 0.948 0.862,1.04 491 4888 0.7709 0.984 0.882,1.1 367 3659
184.11 Malignant neoplasm of ovary neoplasms Female 0.7709 0.984 0.882,1.1 367 3659 0.7709 0.984 0.882,1.1 367 3659
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.4898 0.968 0.883,1.06 526 5253 0.4898 0.968 0.883,1.06 526 5253
185 Cancer of prostate neoplasms Male 0.342 1.02 0.977,1.07 2432 8825 0.2871 1.03 0.979,1.07 2373 8825
187 Cancer of other male genital organs neoplasms Male 0.002188 1.21 1.07,1.38 276 2723 ,
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.8974 1.01 0.822,1.25 96 960 ,
187.2 Malignant neoplasm of testis neoplasms Male 5.495E-7 1.58 1.32,1.89 144 1387 ,
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.06457 0.962 0.924,1.0 2552 20553 0.6166 1.02 0.94,1.11 577 5768
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.9204 0.997 0.942,1.06 1261 12588 0.787 0.981 0.852,1.13 199 1978
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.6683 0.987 0.928,1.05 1083 10823 0.6067 0.984 0.925,1.05 1069 10724
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.7328 0.976 0.849,1.12 202 2010 0.787 0.981 0.852,1.13 199 1978
189.2 Cancer of bladder neoplasms Both 0.1274 0.961 0.913,1.01 1575 13516 0.1824 0.964 0.913,1.02 1420 12426
189.21 Malignant neoplasm of bladder neoplasms Both 0.2089 0.966 0.916,1.02 1456 12558 0.1824 0.964 0.913,1.02 1420 12426
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.5248 1.03 0.946,1.11 601 5841 0.6166 1.02 0.94,1.11 577 5768
190 Cancer of eye neoplasms Both 0.7709 1.03 0.851,1.24 114 1125 0.7603 1.03 0.852,1.25 112 1113
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.4688 1.03 0.957,1.1 904 9040 0.3811 1.04 0.95,1.15 478 4793
191.1 Cancer of brain and nervous system neoplasms Both 0.2518 1.05 0.965,1.15 580 5800 0.3811 1.04 0.95,1.15 478 4793
191.11 Cancer of brain neoplasms Both 0.3926 1.04 0.949,1.14 483 4830 0.3811 1.04 0.95,1.15 478 4793
193 Thyroid cancer neoplasms Both 0.2891 0.961 0.893,1.03 798 7953 0.2864 0.961 0.893,1.03 795 7918
194 Cancer of other endocrine glands neoplasms Both 0.09772 0.889 0.774,1.02 221 2207 0.08318 0.884 0.768,1.02 219 2188
195 Cancer, suspected or other neoplasms Both 0.5 0.992 0.969,1.02 12134 23141 0.125 0.95 0.89,1.01 954 8927
195.1 Malignant neoplasm, other neoplasms Both 0.4819 0.992 0.968,1.02 11693 23098 0.2455 0.986 0.963,1.01 11497 23049
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.1679 0.955 0.895,1.02 970 8963 0.125 0.95 0.89,1.01 954 8927
196 Radiotherapy neoplasms Both 0.2735 0.975 0.931,1.02 2067 15612 0.1892 0.97 0.926,1.02 2034 15574
197 Chemotherapy neoplasms Both 0.6792 1.01 0.973,1.04 4051 21210 0.9057 0.998 0.964,1.03 3968 21163
198 Secondary malignant neoplasm neoplasms Both 0.9817 1.0 0.969,1.03 4986 21474 0.8872 1.01 0.893,1.14 285 2742
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.278 0.979 0.943,1.02 3156 19844 0.1675 0.974 0.937,1.01 3092 19798
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.2203 1.04 0.975,1.12 903 8847 0.3192 1.04 0.967,1.11 879 8820
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.6209 0.981 0.91,1.06 725 7166 0.4786 0.973 0.901,1.05 705 7148
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.07244 1.08 0.993,1.17 643 6395 0.0871 1.07 0.99,1.17 631 6376
198.5 Secondary malignancy of brain/spine neoplasms Both 0.2355 1.06 0.966,1.15 545 5421 0.271 1.05 0.962,1.15 538 5398
198.6 Secondary malignancy of bone neoplasms Both 0.3945 1.03 0.957,1.12 712 6962 0.471 1.03 0.952,1.11 700 6936
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.8091 1.02 0.899,1.15 287 2752 0.8872 1.01 0.893,1.14 285 2742
199 Neoplasm of uncertain behavior neoplasms Both 0.6486 0.993 0.962,1.02 4947 22823 0.6577 1.06 0.829,1.35 71 716
199.4 Neurofibromatosis neoplasms Both 0.5916 1.07 0.84,1.36 72 720 0.6577 1.06 0.829,1.35 71 716
200 Myeloproliferative disease neoplasms Both 0.06918 0.938 0.876,1.01 886 8851 0.507 0.949 0.812,1.11 159 1598
200.1 Polycythemia vera neoplasms Both 0.6653 0.966 0.828,1.13 161 1610 0.507 0.949 0.812,1.11 159 1598
201 Hodgkin's disease neoplasms Both 0.2234 1.12 0.935,1.33 138 1373 0.1626 1.14 0.95,1.36 136 1366
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.9397 1.0 0.947,1.06 1308 13070 0.4083 1.08 0.902,1.29 131 1285
202.2 Non-Hodgkins lymphoma neoplasms Both 0.873 0.995 0.937,1.06 1141 11402 0.4083 1.08 0.902,1.29 131 1285
202.21 Nodular lymphoma neoplasms Both 0.5176 0.974 0.898,1.06 632 6320 0.5702 0.977 0.9,1.06 627 6281
202.22 Reticulosarcoma neoplasms Both 0.4571 1.07 0.9,1.26 137 1355 0.4864 1.06 0.896,1.26 136 1340
202.24 Large cell lymphoma neoplasms Both 0.3945 1.08 0.905,1.29 132 1300 0.4083 1.08 0.902,1.29 131 1285
204 Leukemia neoplasms Both 0.8091 0.989 0.905,1.08 545 5450 0.9817 1.0 0.859,1.17 178 1778
204.1 Lymphoid leukemia neoplasms Both 0.414 1.07 0.915,1.24 187 1870 0.1592 1.14 0.951,1.36 134 1340
204.11 Lymphoid leukemia, acute neoplasms Both 0.3133 1.15 0.876,1.51 58 580 0.2904 1.16 0.881,1.53 57 573
204.12 Lymphoid leukemia, chronic neoplasms Both 0.1358 1.14 0.959,1.37 136 1350 0.1592 1.14 0.951,1.36 134 1340
204.2 Myeloid leukemia neoplasms Both 0.1892 0.91 0.79,1.05 206 2060 0.5082 0.939 0.779,1.13 120 1230
204.21 Myeloid leukemia, acute neoplasms Both 0.3715 0.92 0.766,1.1 124 1240 0.5082 0.939 0.779,1.13 120 1230
204.4 Multiple myeloma neoplasms Both 0.929 0.993 0.853,1.16 180 1795 0.9817 1.0 0.859,1.17 178 1778
208 Benign neoplasm of colon neoplasms Both 0.3083 1.01 0.988,1.04 8098 29324 0.3006 1.01 0.988,1.04 8031 29126
209 Neuroendocrine tumors neoplasms Both 0.1795 1.1 0.958,1.26 222 2220 0.2163 1.09 0.951,1.25 221 2204
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.7621 0.992 0.942,1.04 1584 15798 0.7943 0.993 0.943,1.05 1575 15669
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.881 0.998 0.97,1.03 5807 30296 0.8913 0.998 0.97,1.03 5767 30090
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.3141 1.03 0.975,1.08 1556 15533 0.3614 1.02 0.972,1.08 1539 15414
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.4074 1.02 0.969,1.08 1405 13304 0.4416 1.02 0.967,1.08 1398 13231
214 Lipoma neoplasms Both 0.0631 0.944 0.888,1.0 1117 11124 0.02291 0.913 0.845,0.987 676 6757
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.02089 0.912 0.844,0.986 681 6793 0.02291 0.913 0.845,0.987 676 6757
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.5794 0.99 0.957,1.02 3594 32904 0.4634 0.987 0.954,1.02 3563 32677
216 Benign neoplasm of skin neoplasms Both 0.271 1.01 0.99,1.04 9073 29036 0.8851 1.01 0.834,1.23 109 1085
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.9705 0.996 0.821,1.21 111 1093 0.8851 1.01 0.834,1.23 109 1085
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.4046 0.974 0.917,1.04 1150 11417 0.0955 0.948 0.889,1.01 1051 10526
217.1 Nevus, non-neoplastic neoplasms Both 0.1315 0.953 0.895,1.01 1063 10579 0.0955 0.948 0.889,1.01 1051 10526
218 Benign neoplasm of uterus neoplasms Female 0.335 1.02 0.981,1.06 3552 13845 0.4064 1.02 0.977,1.06 2824 13698
218.1 Uterine leiomyoma neoplasms Female 0.4529 1.02 0.967,1.08 1506 13465 0.4529 1.02 0.967,1.08 1506 13465
218.2 Other benign neoplasm of uterus neoplasms Female 0.4064 1.02 0.976,1.06 2824 13698 0.4064 1.02 0.977,1.06 2824 13698
220 Benign neoplasm of ovary neoplasms Female 0.1932 1.05 0.975,1.14 763 7571 0.1932 1.05 0.975,1.14 763 7571
221 Benign neoplasm of other female genital organs neoplasms Female 0.875 0.996 0.945,1.05 1666 12074 0.875 0.996 0.945,1.05 1666 12074
222 Benign neoplasm of male genital organs neoplasms Male 0.5333 1.02 0.956,1.09 954 9116 0.5808 1.02 0.952,1.09 888 9116
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.5585 1.02 0.963,1.07 1547 11080 0.6546 1.01 0.959,1.07 1518 11017
224 Benign neoplasm of eye neoplasms Both 0.871 1.01 0.919,1.1 511 5062 0.6471 1.02 0.926,1.13 427 4192
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.6653 1.02 0.925,1.13 429 4230 0.6471 1.02 0.926,1.13 427 4192
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.2564 1.04 0.973,1.11 1039 10379 0.1291 1.11 0.971,1.26 240 2404
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.5 1.03 0.953,1.1 817 8160 0.5023 1.03 0.953,1.1 815 8091
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.1361 1.11 0.969,1.26 242 2420 0.1291 1.11 0.971,1.26 240 2404
226 Benign neoplasm of thyroid glands neoplasms Both 0.7379 1.01 0.949,1.08 1082 10810 0.7079 1.01 0.95,1.08 1082 10760
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.8511 0.995 0.941,1.05 1387 13870 0.7691 1.02 0.914,1.13 373 3703
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.1936 0.932 0.838,1.04 375 3745 0.1879 0.931 0.837,1.04 372 3715
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.9977 1.0 0.922,1.08 644 6434 0.9638 1.0 0.923,1.09 643 6405
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.7709 1.02 0.914,1.13 373 3724 0.7691 1.02 0.914,1.13 373 3703
228 Hemangioma and lymphangioma, any site neoplasms Both 0.1574 1.04 0.985,1.1 1517 15150 0.8185 1.01 0.939,1.08 839 8428
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.6516 1.02 0.947,1.09 849 8478 0.8185 1.01 0.939,1.08 839 8428
229 Benign neoplasm of unspecified sites neoplasms Both 0.1219 1.02 0.994,1.05 6631 31223 0.2844 1.02 0.986,1.05 4837 29532
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.173 1.02 0.991,1.05 4904 29712 0.2844 1.02 0.986,1.05 4837 29532
860 Bone marrow or stem cell transplant neoplasms Both 0.811 0.978 0.817,1.17 127 1266 0.9397 0.993 0.826,1.19 123 1254
240 Simple and unspecified goiter endocrine/metabolic Both 0.1355 0.945 0.877,1.02 767 7647 0.1245 0.943 0.876,1.02 766 7623
241 Nontoxic nodular goiter endocrine/metabolic Both 0.26 0.975 0.933,1.02 2274 18240 0.2051 0.959 0.898,1.02 1015 10036
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.863 0.996 0.948,1.05 1795 16440 0.8147 0.994 0.947,1.04 1789 16370
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.207 0.959 0.899,1.02 1017 10065 0.2051 0.959 0.898,1.02 1015 10036
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.8241 0.993 0.932,1.06 1075 10635 0.2404 1.13 0.923,1.38 116 1157
242.1 Graves' disease endocrine/metabolic Both 0.5821 1.03 0.927,1.14 399 3965 0.5808 1.03 0.928,1.14 399 3955
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.8128 1.03 0.828,1.27 98 978 0.7962 1.03 0.83,1.27 98 972
242.3 Exophthalmos endocrine/metabolic Both 0.4276 1.05 0.925,1.2 245 2447 0.2404 1.13 0.923,1.38 116 1157
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.2382 1.13 0.923,1.38 116 1160 0.2404 1.13 0.923,1.38 116 1157
244 Hypothyroidism endocrine/metabolic Both 0.6592 0.994 0.966,1.02 6448 27183 0.5689 0.992 0.963,1.02 5973 26511
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.6152 0.986 0.934,1.04 1421 14153 0.6166 0.986 0.934,1.04 1416 14092
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.8531 0.993 0.926,1.07 853 8502 0.8831 0.995 0.927,1.07 853 8455
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.5781 0.992 0.963,1.02 5996 26719 0.5689 0.992 0.963,1.02 5973 26511
245 Thyroiditis endocrine/metabolic Both 0.8035 0.989 0.908,1.08 574 5720 0.6902 0.981 0.89,1.08 456 4529
245.2 Chronic thyroiditis endocrine/metabolic Both 0.7516 0.985 0.895,1.08 463 4617 0.6902 0.981 0.89,1.08 456 4529
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.6839 0.98 0.89,1.08 456 4533 0.6902 0.981 0.89,1.08 456 4529
246 Other disorders of thyroid endocrine/metabolic Both 0.4932 0.989 0.959,1.02 5018 25158 0.1521 1.07 0.977,1.16 567 5620
246.2 Thyroid cyst endocrine/metabolic Both 0.1442 0.848 0.679,1.06 83 804 0.1449 0.847 0.678,1.06 82 800
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.1656 1.06 0.975,1.16 568 5651 0.1521 1.07 0.977,1.16 567 5620
249 Secondary diabetes mellitus endocrine/metabolic Both 0.5888 1.02 0.945,1.1 686 6849 0.5821 1.02 0.946,1.1 681 6784
250 Diabetes mellitus endocrine/metabolic Both 0.2805 1.01 0.99,1.04 10115 27568 0.2466 0.959 0.892,1.03 815 8105
250.1 Type 1 diabetes endocrine/metabolic Both 0.3048 1.03 0.97,1.1 1053 10521 0.7907 0.969 0.771,1.22 70 683
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.5902 0.936 0.737,1.19 80 792 0.5984 0.938 0.738,1.19 80 786
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.9977 1.0 0.875,1.14 235 2346 0.9594 1.0 0.878,1.15 234 2326
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.879 0.991 0.878,1.12 280 2800 0.9057 0.993 0.88,1.12 280 2776
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.7096 1.03 0.898,1.17 238 2372 0.7031 1.03 0.898,1.17 238 2349
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.7516 0.964 0.767,1.21 70 690 0.7907 0.969 0.771,1.22 70 683
250.2 Type 2 diabetes endocrine/metabolic Both 0.7413 1.0 0.978,1.03 7035 26169 0.2924 0.953 0.871,1.04 509 5020
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.9078 1.01 0.836,1.22 120 1200 0.8872 1.01 0.839,1.23 120 1191
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.3698 1.03 0.967,1.09 1133 11056 0.3606 1.03 0.968,1.09 1123 10959
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.3707 0.968 0.902,1.04 826 8208 0.4571 0.973 0.906,1.05 820 8129
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.5224 1.02 0.964,1.08 1419 13969 0.4436 1.02 0.967,1.08 1405 13842
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.2618 0.95 0.869,1.04 513 5077 0.2924 0.953 0.871,1.04 509 5020
250.3 Insulin pump user endocrine/metabolic Both 0.3819 0.979 0.934,1.03 1884 17814 0.4932 0.984 0.938,1.03 1868 17673
250.4 Abnormal glucose endocrine/metabolic Both 0.1972 1.02 0.99,1.05 5404 26451 0.2037 1.02 0.989,1.05 4689 25710
250.41 Impaired fasting glucose endocrine/metabolic Both 0.3499 0.974 0.92,1.03 1326 13130 0.3882 0.975 0.922,1.03 1317 13054
250.42 Other abnormal glucose endocrine/metabolic Both 0.2438 1.02 0.987,1.05 4736 25883 0.2037 1.02 0.989,1.05 4689 25710
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.2014 1.18 0.917,1.51 78 747 0.2023 1.18 0.917,1.51 78 746
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.4498 1.02 0.963,1.09 1137 11335 0.4121 1.03 0.965,1.09 1127 11233
250.7 Diabetic retinopathy endocrine/metabolic Both 0.1945 0.954 0.888,1.02 821 8168 0.2466 0.959 0.892,1.03 815 8105
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.0309 0.91 0.836,0.992 595 5901 0.5808 0.978 0.904,1.06 701 6978
251.1 Hypoglycemia endocrine/metabolic Both 0.5623 0.977 0.904,1.06 702 7015 0.5808 0.978 0.904,1.06 701 6978
252 Disorders of parathyroid gland endocrine/metabolic Both 0.7278 0.991 0.944,1.04 1807 17879 0.7047 0.98 0.881,1.09 392 3911
252.1 Hyperparathyroidism endocrine/metabolic Both 0.8222 0.994 0.945,1.05 1656 16459 0.869 0.996 0.946,1.05 1652 16382
252.2 Hypoparathyroidism endocrine/metabolic Both 0.6887 0.979 0.88,1.09 393 3922 0.7047 0.98 0.881,1.09 392 3911
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.4775 0.972 0.899,1.05 691 6893 0.0955 1.21 0.967,1.51 93 919
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.7603 1.02 0.884,1.18 205 2041 0.6637 1.05 0.831,1.34 72 716
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.6368 1.06 0.835,1.34 72 720 0.6637 1.05 0.831,1.34 72 716
253.2 Pituitary hypofunction endocrine/metabolic Both 0.7516 0.976 0.841,1.13 184 1840 0.6637 0.967 0.833,1.12 183 1825
253.3 Diabetes insipidus endocrine/metabolic Both 0.9594 0.993 0.775,1.27 70 694 0.7925 0.967 0.754,1.24 69 690
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.863 0.981 0.792,1.22 92 899 0.8453 0.979 0.787,1.22 90 881
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.1021 1.2 0.964,1.5 93 925 0.0955 1.21 0.967,1.51 93 919
255 Disorders of adrenal glands endocrine/metabolic Both 0.2275 0.964 0.908,1.02 1186 11860 0.4159 0.96 0.871,1.06 450 4465
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.811 1.01 0.9,1.14 290 2886 0.2312 1.13 0.926,1.37 106 1052
255.11 Cushing's syndrome endocrine/metabolic Both 0.1742 0.889 0.75,1.05 144 1440 0.1762 0.889 0.75,1.05 143 1432
255.12 Hyperaldosteronism endocrine/metabolic Both 0.2312 1.13 0.926,1.38 106 1057 0.2312 1.13 0.926,1.37 106 1052
255.2 Adrenal hypofunction endocrine/metabolic Both 0.3681 0.958 0.872,1.05 477 4758 0.4159 0.96 0.871,1.06 450 4465
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.4009 0.959 0.87,1.06 451 4496 0.4159 0.96 0.871,1.06 450 4465
256 Ovarian dysfunction endocrine/metabolic Female 0.6281 1.02 0.948,1.09 859 8184 0.9954 1.0 0.914,1.09 544 5436
256.4 Polycystic ovaries endocrine/metabolic Female 0.9954 1.0 0.914,1.09 544 5436 0.9954 1.0 0.914,1.09 544 5436
257 Testicular dysfunction endocrine/metabolic Male 0.2291 0.956 0.889,1.03 747 7455 0.2051 0.953 0.884,1.03 700 7123
257.1 Testicular hypofunction endocrine/metabolic Male 0.2911 0.961 0.893,1.03 725 7234 0.2051 0.953 0.884,1.03 700 7123
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.6998 0.953 0.747,1.22 66 660 0.9183 1.01 0.817,1.25 92 920
258.1 Postablative ovarian failure endocrine/metabolic Female 0.9183 1.01 0.816,1.25 92 920 0.9183 1.01 0.817,1.25 92 920
259 Other endocrine disorders endocrine/metabolic Both 0.06607 1.07 0.995,1.16 759 7562 0.07762 1.07 0.993,1.16 753 7520
260 Protein-calorie malnutrition endocrine/metabolic Both 0.4285 0.983 0.942,1.03 2353 22279 0.861 0.993 0.917,1.07 669 6669
260.1 Cachexia endocrine/metabolic Both 0.5297 1.04 0.915,1.19 239 2388 0.413 1.06 0.926,1.21 234 2362
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.9954 1.0 0.946,1.06 1363 13589 0.3819 0.956 0.863,1.06 410 4099
260.22 Nutritional marasmus endocrine/metabolic Both 0.2938 0.947 0.856,1.05 413 4130 0.3819 0.956 0.863,1.06 410 4099
260.3 Adult failure to thrive endocrine/metabolic Both 0.1094 0.929 0.848,1.02 509 5051 0.1312 0.932 0.851,1.02 504 5012
260.6 Anorexia endocrine/metabolic Both 0.7379 0.987 0.912,1.07 677 6722 0.861 0.993 0.917,1.07 669 6669
261 Vitamin deficiency endocrine/metabolic Both 0.207 1.02 0.99,1.05 5614 30157 0.6397 1.01 0.978,1.04 5234 29654
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.3013 1.04 0.962,1.13 649 6482 0.2972 1.05 0.962,1.14 646 6450
261.4 Vitamin D deficiency endocrine/metabolic Both 0.5794 1.01 0.979,1.04 5264 29859 0.6397 1.01 0.978,1.04 5234 29654
262 Mineral deficiency NEC endocrine/metabolic Both 0.1862 1.05 0.977,1.13 854 8532 0.2477 1.04 0.971,1.12 844 8484
263 Other nutritional deficiency endocrine/metabolic Both 0.4467 1.04 0.939,1.15 412 4113 0.4634 1.04 0.937,1.15 410 4084
264 Lack of normal physiological development endocrine/metabolic Both 0.8531 1.01 0.869,1.18 175 1735 0.9419 0.991 0.772,1.27 60 600
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.6012 1.06 0.858,1.3 95 950 0.6223 1.05 0.854,1.3 94 946
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.869 0.979 0.765,1.25 61 607 0.9419 0.991 0.772,1.27 60 600
269 Proteinuria endocrine/metabolic Both 0.342 0.97 0.911,1.03 1079 10768 0.317 0.968 0.91,1.03 1075 10695
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.7145 1.01 0.94,1.09 740 7378 0.2399 1.09 0.945,1.25 218 2166
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.8433 0.982 0.817,1.18 129 1283 0.4246 0.919 0.748,1.13 100 994
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.389 0.914 0.745,1.12 101 998 0.4246 0.919 0.748,1.13 100 994
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.7834 1.03 0.817,1.31 81 810 0.7745 1.04 0.818,1.31 81 803
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.3899 1.04 0.952,1.13 560 5581 0.2399 1.09 0.945,1.25 218 2166
270.32 Paraproteinemia endocrine/metabolic Both 0.3715 1.06 0.937,1.19 301 2982 0.309 1.06 0.944,1.2 298 2964
270.33 Amyloidosis endocrine/metabolic Both 0.4345 1.12 0.842,1.49 55 550 0.5 1.1 0.829,1.47 54 544
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.241 1.09 0.945,1.25 218 2178 0.2399 1.09 0.945,1.25 218 2166
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.7096 1.01 0.963,1.06 1952 19491 0.3899 0.903 0.715,1.14 81 805
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.6792 1.01 0.963,1.06 1885 18823 0.7244 1.01 0.962,1.06 1869 18719
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.3999 0.905 0.716,1.14 81 810 0.3899 0.903 0.715,1.14 81 805
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.3954 1.01 0.987,1.03 14793 22696 0.07943 0.893 0.787,1.01 242 2405
272.1 Hyperlipidemia endocrine/metabolic Both 0.3631 1.01 0.988,1.03 14763 22682 0.877 0.996 0.953,1.04 2251 15365
272.11 Hypercholesterolemia endocrine/metabolic Both 0.6653 1.01 0.974,1.04 4668 18640 0.5445 1.01 0.977,1.04 4624 18502
272.12 Hyperglyceridemia endocrine/metabolic Both 0.743 1.01 0.946,1.08 945 9395 0.7638 1.01 0.945,1.08 937 9315
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.9354 0.998 0.955,1.04 2272 15492 0.877 0.996 0.953,1.04 2251 15365
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.08511 0.895 0.789,1.02 244 2425 0.07943 0.893 0.787,1.01 242 2405
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.1963 1.03 0.984,1.08 1971 18337 0.4256 1.07 0.905,1.27 140 1348
274.1 Gout endocrine/metabolic Both 0.2037 1.03 0.983,1.08 1879 17712 0.6053 1.02 0.948,1.1 783 7799
274.11 Gouty arthropathy endocrine/metabolic Both 0.6653 1.02 0.945,1.09 793 7891 0.6053 1.02 0.948,1.1 783 7799
274.2 Crystal arthropathies endocrine/metabolic Both 0.2541 1.1 0.933,1.3 146 1425 0.4256 1.07 0.905,1.27 140 1348
274.21 Chondrocalcinosis endocrine/metabolic Both 0.4207 1.07 0.905,1.27 140 1363 0.4256 1.07 0.905,1.27 140 1348
275 Disorders of mineral metabolism endocrine/metabolic Both 0.9484 1.0 0.965,1.04 3252 30253 0.5984 1.07 0.833,1.37 70 699
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.1841 1.05 0.977,1.13 845 8441 0.1914 1.05 0.976,1.13 838 8362
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.955 1.0 0.961,1.04 2502 24757 0.871 1.01 0.943,1.07 1014 10115
275.51 Hypocalcemia endocrine/metabolic Both 0.1439 1.06 0.981,1.14 722 7203 0.1276 1.06 0.983,1.15 720 7160
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.8299 1.01 0.945,1.07 1024 10193 0.871 1.01 0.943,1.07 1014 10115
275.6 Hypercalcemia endocrine/metabolic Both 0.6053 0.983 0.922,1.05 1043 10415 0.6223 0.984 0.922,1.05 1037 10366
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.5035 1.01 0.983,1.04 7227 30901 0.01905 0.791 0.651,0.962 99 986
276.1 Electrolyte imbalance endocrine/metabolic Both 0.4592 1.01 0.981,1.04 4833 28673 0.3899 1.02 0.972,1.08 1620 16075
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.02818 0.894 0.809,0.988 415 4115 0.02399 0.891 0.806,0.985 413 4074
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.133 1.04 0.989,1.09 1857 17982 0.1265 1.04 0.989,1.09 1838 17839
276.13 Hyperpotassemia endocrine/metabolic Both 0.5861 0.988 0.946,1.03 2238 20576 0.5272 0.986 0.944,1.03 2212 20406
276.14 Hypopotassemia endocrine/metabolic Both 0.4365 1.02 0.97,1.07 1626 16160 0.3899 1.02 0.972,1.08 1620 16075
276.4 Acid-base balance disorder endocrine/metabolic Both 0.5715 1.02 0.964,1.07 1593 15855 0.547 1.03 0.926,1.16 348 3473
276.41 Acidosis endocrine/metabolic Both 0.9705 0.999 0.944,1.06 1357 13508 0.9594 0.999 0.944,1.06 1350 13405
276.42 Alkalosis endocrine/metabolic Both 0.5212 1.04 0.928,1.16 350 3498 0.547 1.03 0.926,1.16 348 3473
276.5 Hypovolemia endocrine/metabolic Both 0.507 0.988 0.955,1.02 3615 28901 0.4426 0.986 0.953,1.02 3576 28715
276.6 Fluid overload endocrine/metabolic Both 0.6918 1.01 0.951,1.08 1046 10404 0.6653 1.01 0.952,1.08 1039 10316
276.8 Polydipsia endocrine/metabolic Both 0.02089 0.795 0.654,0.966 99 990 0.01905 0.791 0.651,0.962 99 986
277 Other disorders of metabolism endocrine/metabolic Both 0.6871 1.01 0.959,1.07 1534 15324 0.1202 0.936 0.861,1.02 606 6065
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.6209 0.968 0.852,1.1 252 2520 0.4955 0.956 0.841,1.09 248 2508
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.3673 0.962 0.883,1.05 547 5456 0.3162 0.957 0.878,1.04 539 5404
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.5212 1.03 0.947,1.11 675 6743 0.9183 1.0 0.92,1.1 565 5635
277.51 Lipoprotein disorders endocrine/metabolic Both 0.9462 1.0 0.919,1.09 567 5665 0.9183 1.0 0.92,1.1 565 5635
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.1236 0.937 0.862,1.02 610 6090 0.1202 0.936 0.861,1.02 606 6065
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.1607 1.01 0.994,1.04 15130 23191 0.151 1.04 0.986,1.1 1517 13643
278.1 Obesity endocrine/metabolic Both 0.2559 1.01 0.991,1.03 13507 23193 0.3365 1.01 0.986,1.04 6334 22978
278.11 Morbid obesity endocrine/metabolic Both 0.3724 1.01 0.985,1.04 6376 23143 0.3365 1.01 0.986,1.04 6334 22978
278.3 Localized adiposity endocrine/metabolic Both 0.4909 0.957 0.844,1.08 270 2694 0.5433 0.962 0.848,1.09 268 2690
278.4 Abnormal weight gain endocrine/metabolic Both 0.1618 1.04 0.985,1.1 1522 13685 0.151 1.04 0.986,1.1 1517 13643
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.3776 1.02 0.976,1.07 2245 22393 0.4457 1.04 0.941,1.15 441 4409
279.1 Immunity deficiency endocrine/metabolic Both 0.6457 0.984 0.917,1.05 881 8792 0.9462 0.996 0.872,1.14 252 2524
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.861 0.988 0.867,1.13 254 2540 0.9462 0.996 0.872,1.14 252 2524
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.6561 1.02 0.934,1.11 574 5735 0.6653 1.02 0.934,1.11 572 5716
279.7 Other immunological findings endocrine/metabolic Both 0.5888 0.991 0.958,1.02 3927 30734 0.6516 0.992 0.96,1.03 3890 30535
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.4436 1.04 0.941,1.15 443 4423 0.4457 1.04 0.941,1.15 441 4409
275.1 Disorders of iron metabolism hematopoietic Both 0.5834 0.957 0.817,1.12 168 1680 0.5984 1.07 0.833,1.37 70 699
275.11 Hereditary hemochromatosis hematopoietic Both 0.5998 1.07 0.832,1.37 70 700 0.5984 1.07 0.833,1.37 70 699
280 Iron deficiency anemias hematopoietic Both 0.3819 1.02 0.981,1.05 3537 25593 0.08318 1.05 0.993,1.11 1353 13433
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.3083 1.02 0.983,1.06 3410 25349 0.2858 1.02 0.984,1.06 3389 25183
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.08511 1.05 0.993,1.11 1361 13511 0.08318 1.05 0.993,1.11 1353 13433
281 Other deficiency anemia hematopoietic Both 0.2028 1.07 0.963,1.19 387 3838 0.2523 1.09 0.941,1.26 213 2096
281.1 Megaloblastic anemia hematopoietic Both 0.2944 1.08 0.933,1.26 189 1875 0.5188 1.06 0.888,1.27 135 1340
281.11 Pernicious anemia hematopoietic Both 0.03311 1.29 1.02,1.64 84 830 0.02951 1.3 1.03,1.65 84 827
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.542 1.06 0.885,1.26 135 1348 0.5188 1.06 0.888,1.27 135 1340
281.9 Deficiency anemias hematopoietic Both 0.263 1.09 0.94,1.25 214 2110 0.2523 1.09 0.941,1.26 213 2096
282 Hereditary hemolytic anemias hematopoietic Both 0.0537 1.14 0.998,1.31 248 2443 0.1002 1.16 0.971,1.39 141 1407
282.8 Other hemoglobinopathies hematopoietic Both 0.2938 1.09 0.926,1.29 158 1541 0.2972 1.09 0.925,1.29 156 1528
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.06607 1.18 0.989,1.41 143 1420 0.1002 1.16 0.971,1.39 141 1407
283 Acquired hemolytic anemias hematopoietic Both 0.9908 1.0 0.835,1.2 130 1295 0.2606 1.17 0.888,1.55 53 529
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.2655 1.17 0.887,1.54 54 532 0.2606 1.17 0.888,1.55 53 529
284 Aplastic anemia hematopoietic Both 0.1633 0.94 0.862,1.03 558 5545 0.3357 0.956 0.871,1.05 479 4805
284.1 Pancytopenia hematopoietic Both 0.317 0.954 0.871,1.05 488 4847 0.3357 0.956 0.871,1.05 479 4805
285 Other anemias hematopoietic Both 0.5105 1.01 0.984,1.03 9426 28014 0.6081 0.977 0.895,1.07 545 5492
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.9204 1.0 0.962,1.04 2536 22457 0.865 1.0 0.963,1.05 2519 22293
285.2 Anemia of chronic disease hematopoietic Both 0.7261 1.01 0.959,1.06 1584 15823 0.6081 0.977 0.895,1.07 545 5492
285.21 Anemia in chronic kidney disease hematopoietic Both 0.8035 0.99 0.915,1.07 673 6722 0.8241 0.991 0.916,1.07 669 6668
285.22 Anemia in neoplastic disease hematopoietic Both 0.5649 0.975 0.894,1.06 555 5536 0.6081 0.977 0.895,1.07 545 5492
286 Coagulation defects hematopoietic Both 0.5689 0.989 0.952,1.03 3013 27144 0.5623 0.98 0.915,1.05 884 8699
286.1 Congenital coagulation defects hematopoietic Both 0.1614 1.11 0.958,1.29 190 1889 0.1982 1.14 0.932,1.4 97 968
286.11 Von willebrand's disease hematopoietic Both 0.5768 1.08 0.831,1.4 64 640 0.5754 1.08 0.831,1.4 64 638
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.173 1.15 0.94,1.41 98 973 0.1982 1.14 0.932,1.4 97 968
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.879 0.997 0.957,1.04 2601 20964 0.7447 0.993 0.953,1.03 2569 20801
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.4645 0.905 0.694,1.18 60 590 0.4645 0.905 0.694,1.18 60 590
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.08318 0.877 0.756,1.02 186 1860 0.0631 0.868 0.748,1.01 185 1844
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.2099 1.15 0.925,1.42 92 906 0.2871 1.13 0.905,1.4 90 895
286.6 Defibrination syndrome hematopoietic Both 0.7638 1.01 0.961,1.06 1964 19522 0.9268 1.0 0.956,1.05 1943 19392
286.7 Other and unspecified coagulation defects hematopoietic Both 0.929 1.0 0.96,1.05 2349 23153 0.9506 0.999 0.957,1.04 2322 22997
286.8 Hypercoagulable state hematopoietic Both 0.1702 1.06 0.976,1.15 643 6420 0.2679 1.05 0.965,1.14 613 6134
286.81 Primary hypercoagulable state hematopoietic Both 0.2291 1.05 0.969,1.14 618 6179 0.2679 1.05 0.965,1.14 613 6134
286.9 Abnormal coagulation profile hematopoietic Both 0.5023 0.977 0.913,1.05 890 8770 0.5623 0.98 0.915,1.05 884 8699
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.5224 0.987 0.947,1.03 2575 22699 0.7762 0.967 0.765,1.22 76 758
287.1 Spontaneous ecchymoses hematopoietic Both 4.571E-5 0.713 0.606,0.839 154 1532 6.918E-5 0.717 0.608,0.845 153 1525
287.3 Thrombocytopenia hematopoietic Both 0.871 0.996 0.954,1.04 2297 20909 0.975 0.998 0.904,1.1 429 4314
287.31 Primary thrombocytopenia hematopoietic Both 0.5728 0.973 0.885,1.07 481 4785 0.5346 0.97 0.882,1.07 475 4745
287.32 Secondary thrombocytopenia hematopoietic Both 0.8831 0.993 0.9,1.09 436 4360 0.975 0.998 0.904,1.1 429 4314
287.4 Qualitative platelet defects hematopoietic Both 0.7798 0.967 0.765,1.22 76 760 0.7762 0.967 0.765,1.22 76 758
288 Diseases of white blood cells hematopoietic Both 0.317 1.02 0.984,1.05 3850 30383 0.1211 1.15 0.963,1.38 127 1268
288.1 Decreased white blood cell count hematopoietic Both 0.3524 1.03 0.97,1.09 1252 12520 0.3622 0.968 0.903,1.04 883 8921
288.11 Neutropenia hematopoietic Both 0.4764 0.975 0.91,1.04 896 8960 0.3622 0.968 0.903,1.04 883 8921
288.2 Elevated white blood cell count hematopoietic Both 0.2477 1.02 0.985,1.06 3179 28632 0.2594 1.02 0.984,1.06 3154 28465
288.3 Eosinophilia hematopoietic Both 0.1007 1.16 0.971,1.4 128 1278 0.1211 1.15 0.963,1.38 127 1268
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.5943 0.984 0.929,1.04 1259 12554 0.9141 1.01 0.891,1.14 280 2758
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.618 0.979 0.901,1.06 615 6123 0.6026 0.978 0.9,1.06 612 6107
289.4 Lymphadenitis hematopoietic Both 0.7816 1.01 0.969,1.04 3186 28420 0.857 0.997 0.96,1.03 3118 28253
289.5 Diseases of spleen hematopoietic Both 0.0537 1.12 0.998,1.27 313 3130 0.04266 1.13 1.0,1.27 311 3108
289.8 Polycythemia, secondary hematopoietic Both 0.8017 0.982 0.848,1.14 182 1820 0.6622 0.968 0.836,1.12 180 1808
289.9 Abnormality of red blood cells hematopoietic Both 0.8492 1.01 0.896,1.14 281 2776 0.9141 1.01 0.891,1.14 280 2758
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.5395 0.98 0.92,1.04 1040 9399 1.0 1.0 0.921,1.09 637 6315
290.1 Dementias mental disorders Both 0.7112 0.981 0.885,1.09 407 3816 0.3715 1.14 0.856,1.52 53 506
290.11 Alzheimer's disease mental disorders Both 0.4027 0.919 0.754,1.12 104 984 0.4721 0.929 0.761,1.13 103 975
290.12 Dementia with cerebral degenerations mental disorders Both 0.9616 1.01 0.791,1.28 71 705 0.9528 0.993 0.78,1.26 70 695
290.13 Senile dementia mental disorders Both 0.873 1.01 0.888,1.15 257 2376 0.7962 1.02 0.894,1.16 257 2350
290.16 Vascular dementia mental disorders Both 0.3784 1.14 0.854,1.51 53 508 0.3715 1.14 0.856,1.52 53 506
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.9638 0.998 0.92,1.08 634 6242 0.9661 0.998 0.92,1.08 630 6176
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.859 1.01 0.928,1.09 642 6369 1.0 1.0 0.921,1.09 637 6315
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.9268 0.998 0.953,1.05 1977 19673 0.8492 0.995 0.945,1.05 1551 15382
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.6577 0.964 0.821,1.13 161 1610 0.6383 0.962 0.819,1.13 161 1608
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.6966 1.02 0.918,1.14 364 3634 0.8072 1.01 0.91,1.13 360 3609
291.8 Alteration of consciousness mental disorders Both 0.9795 0.999 0.949,1.05 1563 15497 0.8492 0.995 0.945,1.05 1551 15382
292 Neurological disorders mental disorders Both 0.7362 1.01 0.974,1.04 4340 31695 0.5598 1.05 0.889,1.24 144 1417
292.1 Aphasia/speech disturbance mental disorders Both 0.8091 0.994 0.943,1.05 1554 15459 0.07413 1.16 0.986,1.36 162 1603
292.11 Aphasia mental disorders Both 0.6067 1.02 0.935,1.12 516 5142 0.6577 1.02 0.932,1.12 513 5099
292.12 Symbolic dysfunction mental disorders Both 0.07244 1.16 0.987,1.36 162 1620 0.07413 1.16 0.986,1.36 162 1603
292.2 Mild cognitive impairment mental disorders Both 0.9638 1.0 0.885,1.14 276 2716 0.9572 1.0 0.885,1.14 273 2688
292.3 Memory loss mental disorders Both 0.9183 0.997 0.944,1.05 1405 13752 0.8375 0.994 0.941,1.05 1393 13649
292.4 Altered mental status mental disorders Both 0.6792 1.01 0.963,1.06 1885 18096 0.6855 1.01 0.963,1.06 1872 17951
292.5 Transient alteration of awareness mental disorders Both 0.5534 1.04 0.922,1.16 327 3237 0.5546 1.04 0.922,1.16 326 3221
292.6 Hallucinations mental disorders Both 0.5433 1.05 0.89,1.25 144 1429 0.5598 1.05 0.889,1.24 144 1417
293 Symptoms involving head and neck mental disorders Both 0.1247 0.912 0.811,1.03 304 3036 0.6457 1.01 0.974,1.04 3659 32212
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.5445 1.01 0.977,1.05 3691 32427 0.6457 1.01 0.974,1.04 3659 32212
295 Schizophrenia and other psychotic disorders mental disorders Both 0.7889 0.989 0.915,1.07 664 6564 0.4315 0.965 0.884,1.05 525 5169
295.1 Schizophrenia mental disorders Both 0.6714 0.959 0.791,1.16 111 1080 0.6397 0.955 0.786,1.16 110 1070
295.2 Paranoid disorders mental disorders Both 0.1219 1.19 0.954,1.49 86 856 0.1361 1.19 0.948,1.48 85 856
295.3 Psychosis mental disorders Both 0.4102 0.964 0.883,1.05 527 5206 0.4315 0.965 0.884,1.05 525 5169
296 Mood disorders mental disorders Both 0.9616 0.999 0.976,1.02 12028 17942 0.8395 1.0 0.978,1.03 10706 17808
296.1 Bipolar mental disorders Both 0.9528 1.0 0.938,1.07 994 9331 0.9638 0.998 0.934,1.07 989 9296
296.2 Depression mental disorders Both 0.984 1.0 0.976,1.02 11641 17941 0.8395 1.0 0.978,1.03 10706 17808
296.22 Major depressive disorder mental disorders Both 0.8299 1.0 0.979,1.03 10773 17942 0.8395 1.0 0.978,1.03 10706 17808
297 Suicidal ideation or attempt mental disorders Both 0.1432 1.06 0.98,1.15 696 6932 0.1901 1.1 0.953,1.28 199 2004
297.1 Suicidal ideation mental disorders Both 0.3097 1.05 0.959,1.14 559 5575 0.4198 1.04 0.949,1.13 553 5545
297.2 Suicide or self-inflicted injury mental disorders Both 0.1995 1.1 0.951,1.27 201 2010 0.1901 1.1 0.953,1.28 199 2004
300 Anxiety disorders mental disorders Both 0.6152 0.994 0.971,1.02 12038 17949 0.9441 0.997 0.917,1.08 610 6089
300.1 Anxiety disorder mental disorders Both 0.547 0.993 0.969,1.02 11352 17942 0.5715 0.978 0.906,1.06 724 7198
300.11 Generalized anxiety disorder mental disorders Both 0.5848 0.991 0.958,1.02 4496 17788 0.5636 0.99 0.957,1.02 4470 17656
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.4046 0.972 0.91,1.04 957 9152 0.5297 0.979 0.916,1.05 952 9114
300.13 Phobia mental disorders Both 0.5358 0.976 0.905,1.05 731 7231 0.5715 0.978 0.906,1.06 724 7198
300.3 Obsessive-compulsive disorders mental disorders Both 0.7586 0.979 0.854,1.12 223 2230 0.7161 0.975 0.85,1.12 220 2224
300.4 Dysthymic disorder mental disorders Both 0.3622 0.977 0.93,1.03 1798 13630 0.309 0.975 0.928,1.02 1788 13547
300.8 Acute reaction to stress mental disorders Both 0.399 0.954 0.856,1.06 359 3536 0.26 0.939 0.842,1.05 356 3519
300.9 Posttraumatic stress disorder mental disorders Both 0.9183 0.996 0.916,1.08 612 6113 0.9441 0.997 0.917,1.08 610 6089
301 Personality disorders mental disorders Both 0.4498 0.959 0.861,1.07 363 3626 0.3327 0.929 0.8,1.08 187 1865
301.2 Antisocial/borderline personality disorder mental disorders Both 0.3199 0.927 0.799,1.08 187 1868 0.3327 0.929 0.8,1.08 187 1865
302 Sexual and gender identity disorders mental disorders Both 0.673 1.02 0.936,1.11 608 6055 0.3802 0.951 0.851,1.06 319 3211
302.1 Decreased libido mental disorders Both 0.4732 0.96 0.859,1.07 325 3233 0.3802 0.951 0.851,1.06 319 3211
303 Psychogenic and somatoform disorders mental disorders Both 0.7638 0.99 0.928,1.06 1030 10064 0.7145 0.987 0.922,1.06 922 9070
303.1 Dissociative disorder mental disorders Both 0.4266 0.926 0.765,1.12 115 1144 0.4385 0.927 0.767,1.12 115 1140
303.3 Psychogenic disorder mental disorders Both 0.7762 1.01 0.936,1.09 736 7330 0.5768 0.969 0.866,1.08 337 3360
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.6577 0.975 0.872,1.09 340 3376 0.5768 0.969 0.866,1.08 337 3360
303.4 Somatoform disorder mental disorders Both 0.7551 0.989 0.924,1.06 925 9106 0.7145 0.987 0.922,1.06 922 9070
304 Adjustment reaction mental disorders Both 0.6918 0.992 0.953,1.03 2840 17464 0.6745 0.991 0.952,1.03 2818 17335
305.2 Eating disorder mental disorders Both 0.3206 0.96 0.886,1.04 650 6500 0.2506 0.954 0.88,1.03 647 6487
306 Other mental disorder mental disorders Both 0.9419 0.998 0.94,1.06 1254 10907 0.3681 0.959 0.875,1.05 520 5192
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.3837 1.05 0.943,1.16 418 2847 0.3837 1.05 0.943,1.16 418 2847
306.9 Tension headache mental disorders Both 0.3707 0.959 0.876,1.05 521 5210 0.3681 0.959 0.875,1.05 520 5192
312 Conduct disorders mental disorders Both 0.984 0.998 0.862,1.16 189 1890 0.2495 0.848 0.641,1.12 53 528
312.3 Impulse control disorder mental disorders Both 0.2553 0.85 0.642,1.13 53 530 0.2495 0.848 0.641,1.12 53 528
313 Pervasive developmental disorders mental disorders Both 0.07079 0.946 0.891,1.0 1148 11078 0.6039 1.07 0.825,1.39 60 592
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.1531 0.955 0.896,1.02 1012 9899 0.1849 0.958 0.898,1.02 1008 9832
313.2 Tics and stuttering mental disorders Both 0.6012 1.07 0.826,1.39 60 593 0.6039 1.07 0.825,1.39 60 592
315 Develomental delays and disorders mental disorders Both 0.4529 1.04 0.938,1.15 401 3990 0.4753 1.06 0.905,1.24 181 1784
315.1 Learning disorder mental disorders Both 0.4753 0.916 0.719,1.17 60 599 0.5012 0.92 0.722,1.17 60 596
315.2 Speech and language disorder mental disorders Both 0.3802 1.07 0.917,1.25 182 1801 0.4753 1.06 0.905,1.24 181 1784
316 Substance addiction and disorders mental disorders Both 0.6887 0.992 0.954,1.03 2799 26014 0.7499 0.985 0.9,1.08 509 5160
316.1 Polyneuropathy due to drugs mental disorders Both 0.8279 0.99 0.905,1.08 518 5180 0.7499 0.985 0.9,1.08 509 5160
317 Alcohol-related disorders mental disorders Both 0.1675 0.968 0.924,1.01 1948 17547 0.8166 0.987 0.882,1.1 333 3304
317.1 Alcoholism mental disorders Both 0.4688 0.981 0.931,1.03 1517 14733 0.8166 0.987 0.882,1.1 333 3304
317.11 Alcoholic liver damage mental disorders Both 0.7278 0.98 0.877,1.1 335 3336 0.8166 0.987 0.882,1.1 333 3304
318 Tobacco use disorder mental disorders Both 0.3112 0.988 0.965,1.01 9473 26924 0.2851 0.987 0.964,1.01 9386 26752
320 Meningitis neurological Both 0.6839 1.02 0.914,1.15 319 3181 0.6397 1.03 0.917,1.15 317 3152
323 Encephalitis neurological Both 0.1611 0.891 0.757,1.05 148 1475 0.2704 0.907 0.762,1.08 124 1238
323.8 Encephalitis, non-infectious neurological Both 0.2432 0.902 0.758,1.07 125 1245 0.2704 0.907 0.762,1.08 124 1238
324 Other CNS infection and poliomyelitis neurological Both 0.5152 0.958 0.842,1.09 245 2440 0.547 0.961 0.844,1.09 242 2414
327 Sleep disorders neurological Both 0.859 0.998 0.976,1.02 11517 26652 0.2559 0.853 0.647,1.12 55 547
327.1 Hypersomnia neurological Both 0.4046 0.977 0.925,1.03 1403 13919 0.3199 0.972 0.92,1.03 1389 13836
327.3 Sleep apnea neurological Both 0.4121 0.99 0.965,1.01 8293 26193 0.6622 0.994 0.967,1.02 6476 25356
327.31 Central/nonobstroctive sleep apnea neurological Both 0.05495 0.895 0.799,1.0 326 3234 0.06026 0.897 0.801,1.0 325 3209
327.32 Obstructive sleep apnea neurological Both 0.7161 0.995 0.968,1.02 6534 25537 0.6622 0.994 0.967,1.02 6476 25356
327.4 Insomnia neurological Both 0.369 1.02 0.982,1.05 4197 25860 0.875 1.01 0.938,1.08 871 8694
327.41 Organic or persistent insomnia neurological Both 0.7379 1.01 0.944,1.08 881 8743 0.875 1.01 0.938,1.08 871 8694
327.5 Parasomnia neurological Both 0.2399 0.944 0.858,1.04 459 4583 0.2612 0.946 0.86,1.04 457 4538
327.6 Circadian rhythm sleep disorder neurological Both 0.3516 1.08 0.921,1.26 174 1738 0.4064 1.07 0.913,1.25 173 1726
327.7 Sleep related movement disorders neurological Both 0.2051 0.964 0.912,1.02 1364 13620 0.2559 0.853 0.647,1.12 55 547
327.71 Restless legs syndrome neurological Both 0.342 0.972 0.915,1.03 1214 12132 0.4046 0.975 0.919,1.03 1211 12075
327.72 Sleep related leg cramps neurological Both 0.25 0.851 0.646,1.12 55 550 0.2559 0.853 0.647,1.12 55 547
331 Other cerebral degenerations neurological Both 0.6442 0.98 0.902,1.07 602 5935 0.4436 0.958 0.858,1.07 345 3393
331.1 Hydrocephalus neurological Both 0.5998 0.965 0.846,1.1 246 2447 0.4977 0.955 0.837,1.09 243 2426
331.9 Cerebral degeneration, unspecified neurological Both 0.5012 0.963 0.863,1.07 349 3423 0.4436 0.958 0.858,1.07 345 3393
332 Parkinson's disease neurological Both 0.1086 1.1 0.98,1.23 333 3321 0.1059 1.1 0.98,1.23 329 3289
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.1854 0.971 0.929,1.01 2169 20920 0.4198 0.903 0.705,1.16 64 630
333.1 Essential tremor neurological Both 0.811 0.99 0.908,1.08 551 5488 0.7798 0.988 0.905,1.08 543 5437
333.2 Myoclonus neurological Both 0.5957 1.05 0.872,1.27 117 1160 0.5888 1.05 0.873,1.27 117 1155
333.4 Torsion dystonia neurological Both 0.6427 0.971 0.857,1.1 266 2646 0.6397 0.971 0.857,1.1 264 2633
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.4018 0.9 0.703,1.15 64 640 0.4198 0.903 0.705,1.16 64 630
334 Degenerative disease of the spinal cord neurological Both 0.8531 0.993 0.926,1.07 874 8734 0.9528 1.01 0.766,1.33 57 566
334.1 Spinocerebellar disease neurological Both 0.05888 1.3 0.991,1.71 64 631 0.07943 1.28 0.971,1.69 62 625
334.2 Anterior horn cell disease neurological Both 0.8318 0.977 0.785,1.22 92 920 0.9528 1.01 0.766,1.33 57 566
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.9036 1.02 0.773,1.34 57 570 0.9528 1.01 0.766,1.33 57 566
335 Multiple sclerosis neurological Both 0.6902 0.977 0.871,1.1 330 3284 0.6855 0.977 0.87,1.1 326 3270
337 Disorders of the autonomic nervous system neurological Both 0.5998 0.976 0.893,1.07 528 5257 0.104 1.14 0.973,1.33 183 1816
337.1 Peripheral autonomic neuropathy neurological Both 0.1262 1.13 0.966,1.32 185 1837 0.104 1.14 0.973,1.33 183 1816
338 Pain neurological Both 0.7962 0.997 0.977,1.02 16189 22165 0.4989 0.991 0.966,1.02 8176 21995
338.1 Acute pain neurological Both 0.9354 0.999 0.977,1.02 12567 22166 0.9419 0.999 0.977,1.02 12470 22007
338.2 Chronic pain neurological Both 0.4217 0.99 0.965,1.02 8223 22154 0.4989 0.991 0.966,1.02 8176 21995
339 Other headache syndromes neurological Both 0.7852 0.997 0.972,1.02 8578 27793 0.8453 0.998 0.973,1.02 8545 27557
340 Migraine neurological Both 0.6081 0.992 0.962,1.02 5377 24263 0.9078 0.998 0.959,1.04 2854 18567
340.1 Migrain with aura neurological Both 0.8453 0.996 0.957,1.04 2862 18665 0.9078 0.998 0.959,1.04 2854 18567
341 Other demyelinating diseases of central nervous system neurological Both 0.236 1.13 0.924,1.38 111 1105 0.2466 1.13 0.922,1.37 109 1100
342 Hemiplegia neurological Both 0.4656 1.04 0.933,1.16 360 3589 0.5248 1.04 0.928,1.16 359 3557
343 Infantile cerebral palsy neurological Both 0.5012 0.924 0.733,1.16 75 750 0.4955 0.923 0.733,1.16 75 747
344 Other paralytic syndromes neurological Both 0.7962 0.989 0.907,1.08 564 5640 0.778 0.988 0.906,1.08 562 5594
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.3945 1.02 0.975,1.07 2084 20790 0.6194 1.01 0.966,1.06 1957 19455
345.1 Epilepsy neurological Both 0.5224 1.03 0.945,1.12 607 6053 0.7079 1.02 0.923,1.12 432 4295
345.11 Generalized convulsive epilepsy neurological Both 0.6237 0.966 0.839,1.11 196 1960 0.6383 0.967 0.84,1.11 196 1941
345.12 Partial epilepsy neurological Both 0.6577 1.02 0.927,1.13 434 4333 0.7079 1.02 0.923,1.12 432 4295
345.3 Convulsions neurological Both 0.6039 1.01 0.966,1.06 1967 19598 0.6194 1.01 0.966,1.06 1957 19455
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.1675 0.89 0.754,1.05 142 1404 0.9141 0.988 0.792,1.23 89 877
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.6592 0.987 0.93,1.05 1196 11927 0.7709 0.991 0.934,1.05 1187 11834
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.2094 0.87 0.7,1.08 87 860 0.2128 0.871 0.7,1.08 87 853
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.7998 0.972 0.78,1.21 90 884 0.9141 0.988 0.792,1.23 89 877
347 Cataplexy and narcolepsy neurological Both 0.9528 0.993 0.782,1.26 67 670 0.9484 0.992 0.782,1.26 67 668
348 Other conditions of brain neurological Both 0.7112 1.01 0.956,1.07 1424 14226 0.618 1.01 0.966,1.06 1986 19827
348.2 Cerebral edema and compression of brain neurological Both 0.6237 0.981 0.91,1.06 747 7463 0.5875 0.979 0.908,1.06 744 7401
348.4 Cerebral cysts neurological Both 0.6592 0.967 0.834,1.12 195 1945 0.6653 0.968 0.834,1.12 195 1938
348.7 Coma neurological Both 0.7328 1.03 0.875,1.21 162 1620 0.7328 1.03 0.875,1.21 162 1607
348.8 Encephalopathy, not elsewhere classified neurological Both 0.2884 1.05 0.962,1.14 636 6331 0.2679 1.05 0.964,1.14 634 6281
348.9 Other conditions of brain, NOS neurological Both 0.5916 1.01 0.967,1.06 2001 19979 0.618 1.01 0.966,1.06 1986 19827
349 Other and unspecified disorders of the nervous system neurological Both 0.5943 1.02 0.948,1.1 775 7750 0.5675 1.02 0.949,1.1 768 7675
350 Abnormal movement neurological Both 0.6966 0.994 0.965,1.02 5109 32314 0.743 1.02 0.923,1.12 446 4438
350.1 Abnormal involuntary movements neurological Both 0.9057 0.998 0.957,1.04 2464 24243 0.8204 0.995 0.955,1.04 2441 24071
350.2 Abnormality of gait neurological Both 0.6668 0.992 0.954,1.03 2979 25007 0.6966 0.992 0.955,1.03 2964 24825
350.3 Lack of coordination neurological Both 0.8974 0.995 0.924,1.07 773 7693 0.9226 0.996 0.925,1.07 770 7640
350.5 Abnormal reflex neurological Both 0.8551 1.02 0.859,1.2 143 1430 0.8511 1.02 0.86,1.2 143 1420
350.6 Disturbances of sensation of smell and taste neurological Both 0.7311 1.02 0.924,1.12 448 4480 0.743 1.02 0.923,1.12 446 4438
351 Other peripheral nerve disorders neurological Both 0.5943 1.01 0.979,1.04 5685 28844 0.5728 1.01 0.98,1.04 5649 28625
352 Disorders of other cranial nerves neurological Both 0.6887 0.989 0.936,1.04 1412 14120 0.859 0.993 0.915,1.08 635 6358
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.414 0.959 0.869,1.06 440 4393 0.4519 0.962 0.871,1.06 439 4369
352.2 Facial nerve disorders [CN7] neurological Both 0.9419 0.997 0.92,1.08 640 6400 0.859 0.993 0.915,1.08 635 6358
353 Nerve root and plexus disorders neurological Both 0.3228 1.02 0.982,1.06 3295 28097 0.171 1.17 0.936,1.45 94 919
353.1 Nerve plexus lesions neurological Both 0.7244 0.979 0.873,1.1 308 3077 0.7482 0.981 0.874,1.1 307 3053
353.2 Nerve root lesions neurological Both 0.1892 1.16 0.93,1.44 94 930 0.171 1.17 0.936,1.45 94 919
355 Complex regional/central pain syndrome neurological Both 0.2223 0.94 0.852,1.04 419 4170 0.4603 0.97 0.895,1.05 652 6480
355.1 Chronic pain syndrome neurological Both 0.455 0.97 0.895,1.05 654 6509 0.4603 0.97 0.895,1.05 652 6480
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.2523 1.03 0.98,1.08 1728 17176 0.2582 1.03 0.979,1.08 1715 17039
357 Inflammatory and toxic neuropathy neurological Both 0.1358 1.03 0.99,1.08 2467 24091 0.1416 1.03 0.99,1.08 2443 23914
358 Myoneural disorders neurological Both 0.9638 0.998 0.93,1.07 845 8441 0.4083 0.914 0.738,1.13 84 845
358.1 Myasthenia gravis neurological Both 0.3311 0.9 0.728,1.11 85 850 0.4083 0.914 0.738,1.13 84 845
359 Muscular dystrophies and other myopathies neurological Both 0.2018 0.956 0.891,1.02 868 8655 0.1081 0.943 0.878,1.01 824 8246
359.1 Muscular dystrophies neurological Both 0.8551 1.03 0.777,1.36 52 520 0.8356 1.03 0.779,1.36 52 512
359.2 Myopathy neurological Both 0.1205 0.945 0.88,1.01 833 8306 0.1081 0.943 0.878,1.01 824 8246
360 Disorders of the globe sense organs Both 0.006607 0.762 0.626,0.927 102 1013 0.01047 0.772 0.634,0.941 100 1006
361 Retinal detachments and defects sense organs Both 0.5861 0.976 0.894,1.07 528 5265 0.861 0.988 0.863,1.13 220 2202
361.1 Retinal detachment with retinal defect sense organs Both 0.743 0.978 0.856,1.12 225 2226 0.861 0.988 0.863,1.13 220 2202
362 Other retinal disorders sense organs Both 0.2495 1.03 0.983,1.07 2489 18838 0.7178 0.974 0.843,1.12 200 1981
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.4603 1.02 0.967,1.08 1529 12328 0.8395 1.01 0.95,1.07 1311 10852
362.21 Macular degeneration, dry sense organs Both 0.5957 0.969 0.864,1.09 313 2650 0.6053 0.97 0.864,1.09 310 2633
362.22 Macular degeneration, wet sense organs Both 0.4246 1.09 0.888,1.33 108 881 0.4198 1.09 0.889,1.33 108 871
362.23 Cystoid macular degeneration of retina sense organs Both 0.2427 1.08 0.951,1.22 285 2777 0.3698 1.06 0.935,1.2 280 2755
362.26 Macular puckering of retina sense organs Both 0.2472 1.05 0.967,1.14 645 6254 0.2421 1.05 0.968,1.14 638 6206
362.27 Drusen (degenerative) of retina sense organs Both 0.7568 1.02 0.91,1.14 335 3205 0.7311 1.02 0.911,1.14 332 3185
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.8279 1.01 0.95,1.07 1323 10928 0.8395 1.01 0.95,1.07 1311 10852
362.3 Other nondiabetic retinopathy sense organs Both 0.9931 1.0 0.924,1.08 653 6476 0.673 0.975 0.866,1.1 290 2907
362.31 Separation of retinal layers sense organs Both 0.7129 0.978 0.869,1.1 296 2938 0.673 0.975 0.866,1.1 290 2907
362.4 Retinal vascular changes and abnomalities sense organs Both 0.5272 1.03 0.937,1.14 449 4295 0.5093 1.03 0.938,1.14 446 4260
362.6 Peripheral retinal degenerations sense organs Both 0.5248 1.04 0.918,1.18 262 2600 0.5117 1.04 0.919,1.19 258 2578
362.7 Hereditary retinal dystrophies sense organs Both 0.7516 0.97 0.806,1.17 124 1233 0.7943 0.976 0.811,1.17 124 1225
362.8 Retinal hemorrhage/ischemia sense organs Both 0.195 1.12 0.945,1.32 160 1570 0.2884 1.09 0.926,1.29 159 1558
362.9 Retinal edema sense organs Both 0.6998 0.972 0.843,1.12 202 2001 0.7178 0.974 0.843,1.12 200 1981
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.7362 1.02 0.916,1.13 375 3665 0.8433 0.987 0.867,1.12 245 2409
363.3 Chorioretinal scars sense organs Both 0.7621 0.98 0.862,1.11 249 2430 0.8433 0.987 0.867,1.12 245 2409
364 Corneal opacity and other disorders of cornea sense organs Both 0.7447 0.988 0.92,1.06 809 7919 0.3412 0.889 0.699,1.13 69 669
364.1 Corneal opacity sense organs Both 0.6714 0.975 0.867,1.1 294 2930 0.6699 0.975 0.867,1.1 292 2914
364.2 Corneal edema sense organs Both 0.3767 1.1 0.885,1.38 84 819 0.3758 1.11 0.886,1.38 84 816
364.4 Corneal degenerations sense organs Both 0.1002 1.11 0.98,1.25 274 2719 0.0871 1.11 0.985,1.26 274 2699
364.5 Corneal dystrophy sense organs Both 0.375 0.954 0.859,1.06 377 3673 0.547 0.958 0.832,1.1 205 1999
364.51 Fuchs' dystrophy sense organs Both 0.5754 0.961 0.835,1.11 207 2008 0.547 0.958 0.832,1.1 205 1999
364.9 Cornea replaced by transplant sense organs Both 0.3327 0.887 0.696,1.13 69 677 0.3412 0.889 0.699,1.13 69 669
365 Glaucoma sense organs Both 0.597 1.01 0.966,1.06 1986 17152 0.1607 1.11 0.958,1.3 178 1695
365.1 Open-angle glaucoma sense organs Both 0.1803 0.941 0.86,1.03 523 4963 0.1507 0.915 0.811,1.03 277 2583
365.11 Primary open angle glaucoma sense organs Both 0.1403 0.913 0.81,1.03 281 2609 0.1507 0.915 0.811,1.03 277 2583
365.2 Primary angle-closure glaucoma sense organs Both 0.1667 1.11 0.956,1.29 179 1707 0.1607 1.11 0.958,1.3 178 1695
366 Cataract sense organs Both 0.03311 1.03 1.0,1.06 6335 23476 0.1866 1.02 0.988,1.06 3794 20255
366.1 Nonsenile Cataract sense organs Both 0.01259 0.817 0.697,0.958 163 1622 0.01413 0.82 0.699,0.961 163 1614
366.2 Senile cataract sense organs Both 0.2037 1.02 0.988,1.06 3827 20410 0.1866 1.02 0.988,1.06 3794 20255
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.6067 1.01 0.98,1.03 6553 31745 0.4355 0.974 0.913,1.04 967 9603
367.1 Myopia sense organs Both 0.9333 1.0 0.967,1.04 3578 28818 0.9311 1.0 0.967,1.04 3550 28628
367.2 Astigmatism sense organs Both 0.875 0.997 0.959,1.04 2892 26106 0.873 0.997 0.959,1.04 2873 25933
367.4 Presbyopia sense organs Both 0.9419 0.999 0.963,1.04 3297 24582 0.9727 1.0 0.964,1.04 3279 24413
367.8 Hypermetropia sense organs Both 0.1941 1.04 0.982,1.09 1504 14729 0.1941 1.04 0.982,1.09 1499 14645
367.9 Blindness and low vision sense organs Both 0.4467 0.975 0.914,1.04 976 9663 0.4355 0.974 0.913,1.04 967 9603
368 Visual disturbances sense organs Both 0.1633 1.02 0.991,1.06 4287 32818 0.5636 1.06 0.862,1.31 89 876
368.1 Amblyopia sense organs Both 0.863 1.01 0.919,1.11 484 4830 0.8128 1.01 0.921,1.11 481 4795
368.2 Diplopia and disorders of binocular vision sense organs Both 0.6561 1.02 0.946,1.09 822 8186 0.6792 1.02 0.945,1.09 817 8125
368.3 Anisometropia sense organs Both 0.1841 0.901 0.772,1.05 166 1648 0.1941 0.903 0.774,1.05 166 1638
368.4 Visual field defects sense organs Both 0.3266 1.04 0.966,1.11 879 8777 0.3041 1.04 0.967,1.11 876 8708
368.9 Subjective visual disturbances sense organs Both 0.0309 1.08 1.01,1.16 829 8268 0.5636 1.06 0.862,1.31 89 876
368.91 Psychophysical visual disturbances sense organs Both 0.5623 1.06 0.862,1.31 89 885 0.5636 1.06 0.862,1.31 89 876
369 Infection of the eye sense organs Both 0.6368 1.01 0.968,1.06 2328 22262 0.4909 1.02 0.97,1.07 1965 19315
369.2 Eye infection, viral sense organs Both 0.2904 1.06 0.951,1.18 372 3688 0.2761 1.06 0.952,1.19 369 3668
369.5 Conjunctivitis, infectious sense organs Both 0.5164 1.02 0.969,1.06 1974 19408 0.4909 1.02 0.97,1.07 1965 19315
370 Keratitis sense organs Both 0.1603 1.05 0.982,1.12 1051 10280 0.7194 1.03 0.868,1.23 149 1425
370.1 Corneal ulcer sense organs Both 0.02512 1.21 1.02,1.44 164 1630 0.01549 1.23 1.04,1.46 163 1623
370.2 Superficial keratitis sense organs Both 0.05129 1.11 0.999,1.23 394 3916 0.03388 1.12 1.01,1.24 393 3894
370.3 Keratoconjunctivitis sense organs Both 0.7278 0.984 0.901,1.08 531 5159 0.7194 1.03 0.868,1.23 149 1425
370.31 Keratoconjunctivitis sicca sense organs Both 0.7015 1.03 0.87,1.23 150 1432 0.7194 1.03 0.868,1.23 149 1425
371 Inflammation of the eye sense organs Both 0.4046 1.02 0.979,1.05 3269 26161 0.2649 1.13 0.913,1.39 99 977
371.1 Uveitis, noninfectious or NOS sense organs Both 0.9141 0.994 0.894,1.11 394 3892 0.9484 1.0 0.902,1.12 392 3868
371.2 Conjunctivitis, noninfectious sense organs Both 0.05495 1.08 0.998,1.18 651 6462 0.04266 1.1 1.0,1.21 527 5251
371.21 Allergic conjunctivitis sense organs Both 0.03236 1.11 1.01,1.21 532 5279 0.04266 1.1 1.0,1.21 527 5251
371.3 Inflammation of eyelids sense organs Both 0.6887 1.01 0.967,1.05 2523 21781 0.2649 1.13 0.913,1.39 99 977
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.2254 1.14 0.922,1.41 100 979 0.2649 1.13 0.913,1.39 99 977
372 Disorders of conjunctiva sense organs Both 0.6471 0.983 0.915,1.06 827 8153 0.6501 0.984 0.915,1.06 823 8093
374 Other disorders of eyelids sense organs Both 0.7362 1.01 0.963,1.06 2093 18512 0.3251 1.04 0.963,1.12 756 7375
374.1 Ectropion or entropion sense organs Both 0.3396 1.06 0.944,1.18 337 3251 0.3069 1.06 0.947,1.19 337 3220
374.2 Lagophthalmos sense organs Both 0.01778 1.2 1.03,1.4 192 1900 0.01698 1.21 1.03,1.4 192 1881
374.3 Ptosis of eyelid sense organs Both 0.4178 1.03 0.958,1.11 817 8140 0.414 1.03 0.959,1.11 813 8082
374.6 Dermatochalasis sense organs Both 0.3639 1.04 0.961,1.12 759 7426 0.3251 1.04 0.963,1.12 756 7375
375 Disorders of lacrimal system sense organs Both 0.4819 1.01 0.974,1.06 2683 21054 0.6683 1.02 0.917,1.14 354 3511
375.1 Dry eyes sense organs Both 0.873 1.0 0.965,1.04 2966 21823 0.8851 1.0 0.964,1.04 2942 21687
375.2 Epiphora sense organs Both 0.6714 1.02 0.917,1.14 356 3540 0.6683 1.02 0.917,1.14 354 3511
376 Disorders of the orbit sense organs Both 0.9099 0.993 0.882,1.12 285 2814 0.9016 0.993 0.882,1.12 285 2798
377 Disorders of optic nerve and visual pathways sense organs Both 0.4613 1.03 0.953,1.11 706 7010 0.2148 1.06 0.965,1.17 467 4592
377.1 Optic atrophy sense organs Both 0.7161 0.974 0.848,1.12 200 1997 0.6902 0.972 0.845,1.12 198 1982
377.3 Optic neuritis/neuropathy sense organs Both 0.2286 1.06 0.964,1.17 468 4627 0.2148 1.06 0.965,1.17 467 4592
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.9376 1.0 0.939,1.07 969 9602 0.7745 1.02 0.899,1.15 272 2704
378.1 Strabismus (not specified as paralytic) sense organs Both 0.879 0.994 0.915,1.08 617 6131 0.955 0.998 0.919,1.08 613 6090
378.2 Nystagmus and other irregular eye movements sense organs Both 0.8933 0.988 0.832,1.17 138 1371 0.9226 0.992 0.835,1.18 138 1356
378.5 Paralytic strabismus sense organs Both 0.7063 1.02 0.904,1.16 275 2720 0.7745 1.02 0.899,1.15 272 2704
379 Other disorders of eye sense organs Both 0.2931 1.02 0.984,1.06 3593 24835 0.9016 0.996 0.928,1.07 867 8547
379.1 Scleritis and episcleritis sense organs Both 0.4276 0.933 0.786,1.11 140 1379 0.4989 0.942 0.793,1.12 138 1373
379.2 Disorders of vitreous body sense organs Both 0.6266 1.01 0.969,1.05 2559 18709 0.6138 1.01 0.969,1.05 2535 18570
379.3 Aphakia and other disorders of lens sense organs Both 0.5395 1.07 0.858,1.34 87 838 0.537 1.07 0.859,1.34 87 827
379.4 Anomalies of pupillary function sense organs Both 0.867 0.989 0.866,1.13 231 2303 0.8241 0.985 0.863,1.12 230 2294
379.5 Disorders of iris and ciliary body sense organs Both 0.8472 0.986 0.856,1.14 215 2128 0.8091 1.03 0.794,1.34 61 604
379.51 Pigmentary iris degeneration sense organs Both 0.869 1.02 0.787,1.33 61 610 0.8091 1.03 0.794,1.34 61 604
379.9 Pain, swelling or discharge of eye sense organs Both 0.879 0.995 0.927,1.07 870 8594 0.9016 0.996 0.928,1.07 867 8547
380 Disorders of external ear sense organs Both 0.1641 1.04 0.985,1.09 1634 15553 0.9908 1.0 0.954,1.05 1970 18492
380.1 Otitis externa sense organs Both 0.6412 0.986 0.927,1.05 1124 11213 0.6808 0.987 0.928,1.05 1116 11131
380.4 Impacted cerumen sense organs Both 0.8551 0.996 0.951,1.04 1985 18630 0.9908 1.0 0.954,1.05 1970 18492
381 Otitis media and Eustachian tube disorders sense organs Both 0.2985 1.02 0.983,1.06 3291 29339 0.7015 0.977 0.868,1.1 295 2932
381.1 Otitis media sense organs Both 0.134 1.03 0.99,1.08 2402 23549 0.0955 1.04 0.993,1.09 2031 20045
381.11 Suppurative and unspecified otitis media sense organs Both 0.1151 1.04 0.991,1.09 2037 20175 0.0955 1.04 0.993,1.09 2031 20045
381.2 Eustachian tube disorders sense organs Both 0.5358 0.983 0.93,1.04 1393 13815 0.4909 0.981 0.928,1.04 1386 13739
381.3 Mastoiditis & related conditions sense organs Both 0.3013 1.1 0.917,1.32 126 1260 0.2831 1.11 0.92,1.33 126 1253
381.9 Otorrhea sense organs Both 0.7834 0.984 0.874,1.11 297 2960 0.7015 0.977 0.868,1.1 295 2932
382 Otalgia sense organs Both 0.6592 1.01 0.959,1.07 1425 14188 0.6808 1.01 0.958,1.07 1420 14122
383 Otosclerosis sense organs Both 0.8851 0.985 0.809,1.2 112 1120 0.8892 0.986 0.809,1.2 112 1113
384 Other disorders of tympanic membrane sense organs Both 0.1256 1.09 0.977,1.21 397 3962 0.4188 1.05 0.933,1.18 314 3151
384.4 Perforation of tympanic membrane sense organs Both 0.4295 1.05 0.933,1.18 318 3180 0.4188 1.05 0.933,1.18 314 3151
385 Other disorders of middle ear and mastoid sense organs Both 0.354 1.05 0.944,1.17 358 3580 0.3459 0.907 0.741,1.11 103 1019
385.3 Cholesteatoma sense organs Both 0.2123 1.09 0.953,1.24 245 2450 0.195 1.09 0.956,1.25 245 2428
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.3342 0.905 0.739,1.11 103 1025 0.3459 0.907 0.741,1.11 103 1019
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.875 0.996 0.943,1.05 1441 14255 0.9162 0.998 0.969,1.03 5284 31374
386.1 Meniere's disease sense organs Both 0.7586 0.98 0.861,1.12 248 2464 0.798 0.983 0.864,1.12 248 2453
386.2 Peripheral or central vertigo sense organs Both 0.8531 1.01 0.948,1.07 1209 11971 0.26 1.04 0.971,1.12 880 8707
386.21 Central origin vertigo sense organs Both 0.2904 1.04 0.969,1.11 883 8759 0.26 1.04 0.971,1.12 880 8707
386.3 Labyrinthitis sense organs Both 0.6397 1.01 0.954,1.08 1099 10904 0.5902 1.02 0.956,1.08 1096 10844
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.9462 0.999 0.97,1.03 5315 31605 0.9162 0.998 0.969,1.03 5284 31374
388 Other disorders of ear sense organs Both 0.6109 1.02 0.944,1.1 699 6960 0.5495 1.02 0.947,1.11 696 6921
389 Hearing loss sense organs Both 0.2123 0.983 0.956,1.01 6285 31750 0.542 0.939 0.767,1.15 100 1005
389.1 Sensorineural hearing loss sense organs Both 0.2432 0.978 0.942,1.02 3130 24231 0.1879 0.975 0.939,1.01 3097 24061
389.2 Conductive hearing loss sense organs Both 0.4977 0.974 0.904,1.05 717 7169 0.5309 0.976 0.906,1.05 714 7120
389.3 Degenerative and vascular disorders of ear sense organs Both 0.01072 0.805 0.682,0.951 143 1338 0.01047 0.805 0.681,0.951 143 1328
389.4 Tinnitus sense organs Both 0.8995 1.0 0.954,1.06 1677 16701 0.879 0.996 0.947,1.05 1655 16580
389.5 Disorders of acoustic nerve sense organs Both 0.4989 0.933 0.762,1.14 101 1010 0.542 0.939 0.767,1.15 100 1005
394 Rheumatic disease of the heart valves circulatory system Both 0.2667 0.967 0.911,1.03 1177 11253 0.2877 0.95 0.863,1.04 466 4591
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.9016 1.01 0.893,1.14 284 2766 0.7745 1.02 0.901,1.15 279 2735
394.2 Mitral valve disease circulatory system Both 0.8128 1.01 0.91,1.13 378 3735 0.7551 1.02 0.914,1.13 374 3715
394.3 Aortic valve disease circulatory system Both 0.04169 0.846 0.72,0.994 150 1465 0.03715 0.842 0.717,0.99 149 1437
394.7 Disease of tricuspid valve circulatory system Both 0.2999 0.951 0.865,1.05 468 4624 0.2877 0.95 0.863,1.04 466 4591
395 Heart valve disorders circulatory system Both 0.1782 0.975 0.939,1.01 3169 23926 0.4732 1.03 0.957,1.1 870 8130
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.1493 0.964 0.918,1.01 1754 16787 0.1637 0.965 0.919,1.01 1742 16694
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.8072 0.994 0.944,1.05 1619 13932 0.7379 0.991 0.941,1.04 1601 13805
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.5623 1.03 0.927,1.15 373 3704 0.4634 1.04 0.934,1.16 371 3677
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.6339 0.95 0.77,1.17 84 831 0.6982 0.959 0.776,1.19 83 830
395.6 Heart valve replaced circulatory system Both 0.4467 1.03 0.958,1.1 878 8213 0.4732 1.03 0.957,1.1 870 8130
396 Abnormal heart sounds circulatory system Both 0.4677 0.987 0.954,1.02 3754 28453 0.3954 0.985 0.952,1.02 3720 28275
401 Hypertension circulatory system Both 0.3491 0.989 0.967,1.01 18784 19071 0.3296 0.977 0.931,1.02 2014 12862
401.1 Essential hypertension circulatory system Both 0.3034 0.988 0.966,1.01 18655 19070 0.3467 0.989 0.967,1.01 18508 18946
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.6761 0.991 0.947,1.04 2599 12045 0.2606 0.972 0.926,1.02 1994 10818
401.21 Hypertensive heart disease circulatory system Both 0.4207 1.04 0.949,1.13 556 4628 0.3715 1.04 0.953,1.14 553 4588
401.22 Hypertensive chronic kidney disease circulatory system Both 0.2291 0.97 0.924,1.02 2015 10909 0.2606 0.972 0.926,1.02 1994 10818
401.3 Other hypertensive complications circulatory system Both 0.2979 0.975 0.93,1.02 2027 12961 0.3296 0.977 0.931,1.02 2014 12862
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.975 1.0 0.956,1.05 2132 15248 0.929 1.0 0.957,1.05 2116 15143
411 Ischemic Heart Disease circulatory system Both 0.8551 1.0 0.975,1.03 6970 25468 0.04467 0.893 0.8,0.997 332 3221
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.7413 1.01 0.937,1.1 702 6842 0.811 1.01 0.934,1.09 697 6771
411.2 Myocardial infarction circulatory system Both 0.2818 0.978 0.94,1.02 2849 17983 0.1811 0.973 0.935,1.01 2816 17834
411.3 Angina pectoris circulatory system Both 0.2009 1.03 0.984,1.08 1904 15218 0.2193 1.03 0.982,1.08 1890 15087
411.4 Coronary atherosclerosis circulatory system Both 0.9484 1.0 0.971,1.03 5938 22890 0.7962 0.976 0.809,1.18 117 1137
411.41 Aneurysm and dissection of heart circulatory system Both 0.8147 0.978 0.811,1.18 117 1149 0.7962 0.976 0.809,1.18 117 1137
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.6966 1.01 0.974,1.04 4877 21174 0.7745 1.0 0.973,1.04 4832 21017
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.0631 0.901 0.808,1.01 335 3247 0.04467 0.893 0.8,0.997 332 3221
414 Other forms of chronic heart disease circulatory system Both 0.879 0.997 0.955,1.04 2360 18485 0.2698 0.949 0.864,1.04 484 4803
414.2 ASCVD circulatory system Both 0.3177 0.954 0.87,1.05 492 4846 0.2698 0.949 0.864,1.04 484 4803
415 Pulmonary heart disease circulatory system Both 0.6053 1.01 0.971,1.05 2726 25061 0.9484 0.997 0.916,1.09 590 5857
415.1 Acute pulmonary heart disease circulatory system Both 0.2858 1.03 0.976,1.08 1510 15045 0.2864 1.03 0.976,1.09 1487 14887
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.2818 1.03 0.976,1.09 1507 15014 0.2864 1.03 0.976,1.09 1487 14887
415.2 Chronic pulmonary heart disease circulatory system Both 0.5521 0.984 0.933,1.04 1506 14839 0.9484 0.997 0.916,1.09 590 5857
415.21 Primary pulmonary hypertension circulatory system Both 0.9141 0.995 0.915,1.08 592 5901 0.9484 0.997 0.916,1.09 590 5857
416 Cardiomegaly circulatory system Both 0.787 0.991 0.926,1.06 935 9293 0.877 0.995 0.93,1.06 930 9219
418 Nonspecific chest pain circulatory system Both 0.9333 0.999 0.976,1.02 10015 28233 0.3936 1.03 0.967,1.09 1182 11733
418.1 Precordial pain circulatory system Both 0.3936 1.03 0.967,1.09 1193 11816 0.3936 1.03 0.967,1.09 1182 11733
420 Carditis circulatory system Both 0.811 0.993 0.937,1.05 1275 12633 0.6792 1.02 0.936,1.11 595 5925
420.1 Myocarditis circulatory system Both 0.5129 1.08 0.851,1.38 76 752 0.5093 1.09 0.852,1.38 76 748
420.2 Pericarditis circulatory system Both 0.207 0.95 0.878,1.03 684 6830 0.2871 1.13 0.904,1.4 92 907
420.21 Acute pericarditis circulatory system Both 0.7447 1.03 0.869,1.22 144 1435 0.7656 1.03 0.866,1.22 143 1424
420.22 Chronic pericarditis circulatory system Both 0.2904 1.13 0.904,1.4 92 912 0.2871 1.13 0.904,1.4 92 907
420.3 Endocarditis circulatory system Both 0.7447 1.01 0.933,1.1 602 5990 0.6792 1.02 0.936,1.11 595 5925
425 Cardiomyopathy circulatory system Both 0.929 1.0 0.952,1.05 1617 15758 0.9863 1.0 0.78,1.29 71 704
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.7295 1.01 0.958,1.06 1557 15170 0.5875 1.05 0.89,1.23 153 1528
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.857 1.01 0.869,1.18 171 1699 0.7551 1.02 0.878,1.2 170 1683
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.5781 1.05 0.891,1.23 154 1540 0.5875 1.05 0.89,1.23 153 1528
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.05623 0.882 0.775,1.0 248 2480 0.06607 0.885 0.777,1.01 243 2461
425.8 Other cardiomyopathy circulatory system Both 0.975 1.0 0.782,1.29 71 709 0.9863 1.0 0.78,1.29 71 704
426 Cardiac conduction disorders circulatory system Both 0.9162 1.0 0.976,1.03 9881 21221 0.8054 0.99 0.912,1.07 619 5630
426.2 Atrioventricular [AV] block circulatory system Both 0.8241 1.01 0.953,1.06 1527 9610 0.4875 1.06 0.9,1.25 160 1467
426.21 First degree AV block circulatory system Both 0.5333 1.02 0.957,1.09 1064 7510 0.5715 1.02 0.955,1.09 1051 7433
426.22 Mobitz II AV block circulatory system Both 0.5445 1.08 0.833,1.41 56 513 0.5636 1.08 0.83,1.41 56 508
426.23 Second degree AV block circulatory system Both 0.7345 0.973 0.828,1.14 161 1459 0.778 0.977 0.832,1.15 161 1440
426.24 Atrioventricular block, complete circulatory system Both 0.7568 0.983 0.882,1.1 357 3041 0.8128 0.987 0.885,1.1 354 3001
426.25 Other heart block circulatory system Both 0.5093 1.06 0.898,1.24 161 1489 0.4875 1.06 0.9,1.25 160 1467
426.3 Bundle branch block circulatory system Both 0.7379 0.991 0.942,1.04 1775 11373 0.5 0.974 0.902,1.05 714 6154
426.31 Right bundle branch block circulatory system Both 0.7211 0.989 0.929,1.05 1101 8763 0.7568 0.99 0.93,1.05 1090 8677
426.32 Left bundle branch block circulatory system Both 0.3724 0.966 0.895,1.04 721 6217 0.5 0.974 0.902,1.05 714 6154
426.4 Anomalous atrioventricular excitation circulatory system Both 0.787 0.965 0.744,1.25 62 611 0.7015 0.95 0.732,1.23 61 609
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.8995 1.0 0.975,1.03 8452 21094 0.9162 1.0 0.975,1.03 8382 20946
426.8 Other cardiac conduction disorders circulatory system Both 0.1762 1.07 0.97,1.18 456 4529 0.1352 1.08 0.977,1.19 453 4496
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.5534 1.02 0.959,1.08 1261 8802 0.8054 0.99 0.912,1.07 619 5630
426.91 Cardiac pacemaker in situ circulatory system Both 0.7482 0.988 0.919,1.06 836 6124 0.7194 0.987 0.918,1.06 829 6060
426.92 Cardiac defibrillator in situ circulatory system Both 0.871 0.993 0.916,1.08 628 5698 0.8054 0.99 0.912,1.07 619 5630
427 Cardiac dysrhythmias circulatory system Both 0.8035 0.997 0.975,1.02 14018 21321 0.5636 1.01 0.974,1.05 3406 20025
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.3837 0.979 0.933,1.03 1882 14769 0.7674 1.01 0.943,1.08 886 7892
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.26 0.966 0.911,1.03 1193 11216 0.2624 0.966 0.911,1.03 1184 11137
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.8851 1.01 0.938,1.08 892 7975 0.7674 1.01 0.943,1.08 886 7892
427.2 Atrial fibrillation and flutter circulatory system Both 0.8414 1.0 0.968,1.04 4194 15493 0.6653 1.01 0.959,1.07 1581 9581
427.21 Atrial fibrillation circulatory system Both 0.6745 1.01 0.972,1.05 4097 15312 0.7852 1.01 0.969,1.04 4052 15190
427.22 Atrial flutter circulatory system Both 0.7413 1.01 0.956,1.07 1598 9674 0.6653 1.01 0.959,1.07 1581 9581
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.4395 0.989 0.962,1.02 7129 21276 0.4093 0.988 0.961,1.02 7072 21125
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.6982 1.02 0.923,1.13 419 4137 0.877 1.01 0.9,1.13 320 3154
427.41 Ventricular fibrillation and flutter circulatory system Both 0.3097 1.09 0.926,1.27 167 1670 0.3055 1.09 0.926,1.28 167 1644
427.42 Cardiac arrest circulatory system Both 0.7727 1.02 0.907,1.14 321 3186 0.877 1.01 0.9,1.13 320 3154
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.9931 1.0 0.97,1.03 5521 21271 0.9931 1.0 0.97,1.03 5482 21120
427.6 Premature beats circulatory system Both 0.7413 0.992 0.944,1.04 1820 13218 0.5754 0.974 0.89,1.07 517 4832
427.61 Supraventricular premature beats circulatory system Both 0.6039 0.976 0.892,1.07 522 4879 0.5754 0.974 0.89,1.07 517 4832
427.7 Tachycardia NOS circulatory system Both 0.3258 1.02 0.983,1.05 3980 21286 0.3664 1.02 0.982,1.05 3943 21136
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.879 0.994 0.921,1.07 738 6224 0.8128 0.991 0.918,1.07 731 6163
427.9 Palpitations circulatory system Both 0.6039 1.01 0.973,1.05 3420 20157 0.5636 1.01 0.974,1.05 3406 20025
428 Congestive heart failure; nonhypertensive circulatory system Both 0.857 0.997 0.96,1.03 3326 19946 0.9311 0.997 0.939,1.06 1198 10520
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.4519 0.985 0.947,1.02 2965 19130 0.492 0.986 0.948,1.03 2941 18983
428.2 Heart failure NOS circulatory system Both 0.7727 0.994 0.955,1.04 2781 17962 0.8091 0.995 0.955,1.04 2755 17818
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.4699 1.02 0.964,1.08 1288 11396 0.3954 1.03 0.968,1.09 1275 11293
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.857 0.995 0.937,1.06 1208 10616 0.9311 0.997 0.939,1.06 1198 10520
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.1556 1.02 0.993,1.04 9394 27581 0.6124 0.978 0.899,1.06 585 5756
429.1 Heart transplant/surgery circulatory system Both 0.8414 1.01 0.937,1.08 823 8070 0.881 1.01 0.936,1.08 819 7989
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.3664 1.02 0.982,1.05 4445 23965 0.4055 1.01 0.981,1.05 4412 23797
429.3 Symptoms involving cardiovascular system circulatory system Both 0.2793 1.01 0.988,1.04 7147 27443 0.3899 1.01 0.985,1.04 7092 27253
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.6383 0.98 0.901,1.07 591 5816 0.6124 0.978 0.899,1.06 585 5756
430 Intracranial hemorrhage circulatory system Both 0.4325 1.03 0.952,1.12 633 6305 0.1982 1.11 0.948,1.29 200 1992
430.1 Subarachnoid hemorrhage circulatory system Both 0.2188 1.09 0.95,1.25 230 2300 0.2128 1.09 0.951,1.25 230 2289
430.2 Intracerebral hemorrhage circulatory system Both 0.4365 1.05 0.932,1.18 314 3132 0.389 1.05 0.936,1.18 312 3104
430.3 Subdural hemorrhage circulatory system Both 0.1503 1.12 0.96,1.31 202 2017 0.1982 1.11 0.948,1.29 200 1992
433 Cerebrovascular disease circulatory system Both 0.3141 1.02 0.984,1.05 4361 26660 0.8872 0.994 0.909,1.09 530 5247
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.3296 0.974 0.924,1.03 1533 12978 0.5117 1.09 0.844,1.41 60 597
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.9397 0.994 0.855,1.16 188 1858 0.8375 0.984 0.846,1.14 186 1843
433.12 Cerebral atherosclerosis circulatory system Both 0.4775 1.1 0.85,1.42 61 599 0.5117 1.09 0.844,1.41 60 597
433.2 Occlusion of cerebral arteries circulatory system Both 0.08128 1.04 0.995,1.09 1926 17593 0.08318 1.04 0.994,1.1 1851 16871
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.06457 1.05 0.997,1.1 1862 17011 0.08318 1.04 0.994,1.1 1851 16871
433.3 Cerebral ischemia circulatory system Both 0.1754 1.03 0.986,1.08 2122 18040 0.597 1.01 0.965,1.06 1805 15937
433.31 Transient cerebral ischemia circulatory system Both 0.5445 1.02 0.967,1.07 1812 16062 0.597 1.01 0.965,1.06 1805 15937
433.5 Cerebral aneurysm circulatory system Both 0.6761 1.02 0.922,1.13 408 4070 0.6998 1.02 0.921,1.13 408 4051
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.2553 1.06 0.957,1.18 383 3803 0.2612 1.06 0.956,1.18 382 3773
433.8 Late effects of cerebrovascular disease circulatory system Both 0.9226 0.996 0.911,1.09 534 5286 0.8872 0.994 0.909,1.09 530 5247
440 Atherosclerosis circulatory system Both 0.2301 0.972 0.927,1.02 1946 16499 0.7816 1.01 0.935,1.09 697 6721
440.1 Atherosclerosis of renal artery circulatory system Both 0.1807 1.11 0.953,1.29 187 1855 0.1549 1.12 0.959,1.3 185 1840
440.2 Atherosclerosis of the extremities circulatory system Both 0.1233 0.954 0.899,1.01 1166 11265 0.4875 0.975 0.907,1.05 803 7910
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.08913 0.88 0.759,1.02 183 1815 0.07943 0.876 0.755,1.02 182 1792
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.537 0.978 0.91,1.05 812 7979 0.4875 0.975 0.907,1.05 803 7910
440.9 Atherosclerosis of aorta circulatory system Both 0.8974 1.01 0.929,1.09 702 6800 0.7816 1.01 0.935,1.09 697 6721
441 Vascular insufficiency of intestine circulatory system Both 0.9528 0.997 0.9,1.1 407 4039 0.5585 1.06 0.871,1.29 121 1200
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.4887 0.951 0.824,1.1 206 2025 0.507 0.952 0.825,1.1 204 2006
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.5808 1.06 0.868,1.29 122 1207 0.5585 1.06 0.871,1.29 121 1200
442 Other aneurysm circulatory system Both 0.5236 1.01 0.971,1.06 2309 18098 0.6668 0.975 0.87,1.09 326 3276
442.1 Aortic aneurysm circulatory system Both 0.8453 0.995 0.947,1.05 1703 13812 0.3451 0.969 0.908,1.03 983 8920
442.11 Abdominal aortic aneurysm circulatory system Both 0.3622 0.97 0.909,1.04 992 9021 0.3451 0.969 0.908,1.03 983 8920
442.2 Aneurysm of iliac artery circulatory system Both 0.2661 1.09 0.935,1.28 177 1769 0.3055 1.09 0.928,1.27 174 1749
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.5176 0.943 0.791,1.13 137 1357 0.5689 0.949 0.794,1.14 134 1342
442.4 Arterial dissection circulatory system Both 0.01698 1.23 1.04,1.47 156 1555 0.0263 1.22 1.02,1.45 154 1543
442.8 Aneurysm of other specified artery circulatory system Both 0.6745 0.976 0.872,1.09 330 3300 0.6668 0.975 0.87,1.09 326 3276
443 Peripheral vascular disease circulatory system Both 0.6012 0.989 0.947,1.03 2355 20353 0.5321 0.984 0.937,1.03 1728 15024
443.1 Raynaud's syndrome circulatory system Both 0.3802 0.964 0.887,1.05 608 6051 0.3105 0.958 0.881,1.04 602 6031
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.7568 1.03 0.861,1.23 141 1375 0.7674 1.03 0.86,1.23 141 1366
443.8 Other specified peripheral vascular diseases circulatory system Both 0.4519 0.982 0.937,1.03 1899 17476 0.3698 0.978 0.933,1.03 1878 17351
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.5741 0.986 0.938,1.04 1747 15154 0.5321 0.984 0.937,1.03 1728 15024
444 Arterial embolism and thrombosis circulatory system Both 0.9705 0.999 0.922,1.08 675 6732 0.2489 1.11 0.928,1.33 128 1265
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.2944 0.933 0.818,1.06 240 2392 0.2938 0.932 0.817,1.06 235 2367
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.2168 1.12 0.936,1.34 129 1282 0.2489 1.11 0.928,1.33 128 1265
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.03715 1.12 1.01,1.26 367 3641 0.0166 1.19 1.03,1.37 230 2269
446.4 Wegener's granulomatosis circulatory system Both 0.7691 1.03 0.829,1.29 86 857 0.7691 1.03 0.829,1.29 86 852
446.5 Giant cell arteritis circulatory system Both 0.04266 1.32 1.01,1.73 59 547 0.02089 1.38 1.05,1.82 58 544
446.9 Arteritis NOS circulatory system Both 0.01995 1.18 1.03,1.36 230 2285 0.0166 1.19 1.03,1.37 230 2269
447 Other disorders of arteries and arterioles circulatory system Both 0.3776 1.02 0.976,1.07 2116 18819 0.2301 1.05 0.969,1.14 629 6240
447.1 Stricture of artery circulatory system Both 0.7379 0.984 0.892,1.08 435 4322 0.7907 0.987 0.895,1.09 433 4283
447.7 Aortic ectasia circulatory system Both 0.3516 1.04 0.958,1.13 637 6315 0.2301 1.05 0.969,1.14 629 6240
448 Disease of capillaries circulatory system Both 0.01738 0.918 0.855,0.985 853 8472 0.01698 0.917 0.854,0.985 846 8425
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.2582 0.971 0.924,1.02 1701 17006 0.2296 0.97 0.922,1.02 1683 16921
451 Phlebitis and thrombophlebitis circulatory system Both 0.5662 1.03 0.941,1.12 582 5764 0.6792 0.969 0.836,1.12 188 1875
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.6223 0.964 0.832,1.12 190 1888 0.6792 0.969 0.836,1.12 188 1875
452 Other venous embolism and thrombosis circulatory system Both 0.7278 0.994 0.96,1.03 3773 25068 0.6281 0.956 0.796,1.15 118 1168
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.1524 1.11 0.963,1.27 228 2277 0.2173 1.09 0.95,1.25 225 2257
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.5333 0.987 0.948,1.03 2623 22444 0.4198 0.983 0.944,1.02 2599 22295
452.8 Postphlebitic syndrome circulatory system Both 0.811 0.978 0.815,1.17 119 1181 0.6281 0.956 0.796,1.15 118 1168
453 Chronic venous hypertension circulatory system Both 0.2831 1.09 0.932,1.27 173 1715 0.2466 1.1 0.938,1.28 172 1710
454 Varicose veins circulatory system Both 0.975 0.999 0.956,1.04 2206 20243 0.8375 0.994 0.936,1.06 1171 11700
454.1 Varicose veins of lower extremity circulatory system Both 0.9462 0.998 0.952,1.05 1908 17574 0.8375 0.994 0.936,1.06 1171 11700
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.879 0.995 0.937,1.06 1182 11754 0.8375 0.994 0.936,1.06 1171 11700
455 Hemorrhoids circulatory system Both 0.8375 1.0 0.971,1.04 4379 24588 0.7962 1.0 0.972,1.04 4336 24438
456 Chronic venous insufficiency [CVI] circulatory system Both 0.5821 1.01 0.969,1.06 2303 20367 0.5848 1.01 0.969,1.06 2291 20259
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.5309 0.985 0.939,1.03 1946 14131 0.597 0.987 0.94,1.04 1827 13547
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.5902 0.968 0.86,1.09 287 2845 0.5458 0.964 0.856,1.09 286 2815
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.5458 0.985 0.938,1.03 1841 13661 0.597 0.987 0.94,1.04 1827 13547
458 Hypotension circulatory system Both 0.2958 1.02 0.985,1.05 4073 28546 0.3365 1.02 0.982,1.05 3611 27273
458.1 Orthostatic hypotension circulatory system Both 0.3027 1.03 0.97,1.1 1031 10176 0.3048 1.03 0.97,1.1 1025 10095
458.2 Iatrogenic hypotension circulatory system Both 0.4819 0.976 0.912,1.04 911 9084 0.5433 0.979 0.915,1.05 903 8996
458.9 Hypotension NOS circulatory system Both 0.3027 1.02 0.984,1.05 3641 27465 0.3365 1.02 0.982,1.05 3611 27273
459 Other disorders of circulatory system circulatory system Both 0.6792 0.993 0.958,1.03 3553 27674 0.6281 0.99 0.952,1.03 2731 23483
459.1 Hemorrhage NOS circulatory system Both 0.7499 1.01 0.933,1.1 619 6159 0.6823 1.02 0.937,1.1 616 6111
459.7 Blood vessel replaced circulatory system Both 0.5623 1.04 0.905,1.2 203 2030 0.561 1.04 0.905,1.2 202 1999
459.9 Circulatory disease NEC circulatory system Both 0.6966 0.992 0.954,1.03 2757 23656 0.6281 0.99 0.952,1.03 2731 23483
464 Acute sinusitis respiratory Both 0.7499 0.994 0.96,1.03 3675 26562 0.7328 0.994 0.96,1.03 3652 26400
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.7586 1.0 0.978,1.03 7223 30143 0.2729 0.941 0.844,1.05 344 3426
465.2 Acute pharyngitis respiratory Both 0.8831 1.0 0.969,1.04 3967 26715 0.8241 1.0 0.97,1.04 3942 26540
465.4 Acute laryngitis and tracheitis respiratory Both 0.2472 0.938 0.841,1.05 345 3441 0.2729 0.941 0.844,1.05 344 3426
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.3828 0.976 0.925,1.03 1431 14130 0.3776 0.976 0.924,1.03 1421 14016
471 Nasal polyps respiratory Both 0.865 0.992 0.903,1.09 475 4727 0.9036 0.994 0.905,1.09 475 4691
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.865 0.995 0.94,1.05 1344 13251 0.7345 0.99 0.936,1.05 1333 13178
473 Diseases of the larynx and vocal cords respiratory Both 0.415 0.983 0.942,1.03 2393 20985 0.4246 0.981 0.935,1.03 1866 17909
473.1 Chronic laryngitis respiratory Both 0.2985 0.863 0.654,1.14 57 562 0.2911 0.86 0.65,1.14 56 559
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.05754 0.917 0.838,1.0 517 5167 0.0631 0.918 0.839,1.0 514 5132
473.4 Voice disturbance respiratory Both 0.4581 0.982 0.937,1.03 1880 18033 0.4246 0.981 0.935,1.03 1866 17909
474 Acute and chronic tonsillitis respiratory Both 0.9638 0.998 0.923,1.08 685 6193 0.8892 0.994 0.911,1.08 553 5139
474.1 Acute tonsillitis respiratory Both 0.9099 0.993 0.874,1.13 267 2507 0.8166 0.985 0.867,1.12 265 2498
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.8974 0.994 0.912,1.08 555 5166 0.8892 0.994 0.911,1.08 553 5139
475 Chronic sinusitis respiratory Both 0.156 1.03 0.99,1.06 3434 23149 0.8974 1.01 0.927,1.09 647 6407
475.9 Postnasal drip respiratory Both 0.8241 1.01 0.931,1.09 651 6441 0.8974 1.01 0.927,1.09 647 6407
476 Allergic rhinitis respiratory Both 0.1888 0.984 0.962,1.01 10205 23354 0.15 0.983 0.96,1.01 10139 23179
477 Epistaxis or throat hemorrhage respiratory Both 0.2 0.957 0.894,1.02 895 8841 0.2113 0.957 0.894,1.02 890 8777
478 Throat pain respiratory Both 0.3532 0.948 0.848,1.06 325 3233 0.4074 0.954 0.852,1.07 322 3209
479 Other upper respiratory disease respiratory Both 0.9594 1.0 0.969,1.03 4428 23338 0.9727 0.999 0.968,1.03 4391 23163
480 Pneumonia respiratory Both 0.869 1.0 0.972,1.03 4823 30881 0.9528 0.994 0.822,1.2 116 1162
480.1 Bacterial pneumonia respiratory Both 0.9036 1.0 0.937,1.08 860 8567 0.5297 0.929 0.739,1.17 81 808
480.11 Pneumococcal pneumonia respiratory Both 0.6095 1.03 0.926,1.14 372 3720 0.5058 1.04 0.933,1.15 366 3681
480.12 Pseudomonal pneumonia respiratory Both 0.7447 0.969 0.802,1.17 121 1192 0.7568 0.971 0.803,1.17 120 1174
480.13 MRSA pneumonia respiratory Both 0.5821 0.938 0.747,1.18 82 818 0.5297 0.929 0.739,1.17 81 808
480.2 Viral pneumonia respiratory Both 0.507 1.06 0.896,1.25 147 1461 0.4864 1.06 0.898,1.25 146 1452
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.9506 1.01 0.834,1.21 117 1170 0.9572 1.01 0.831,1.22 113 1161
480.5 Bronchopneumonia and lung abscess respiratory Both 0.9572 1.01 0.833,1.21 119 1175 0.9528 0.994 0.822,1.2 116 1162
481 Influenza respiratory Both 0.7762 0.991 0.928,1.06 990 9863 0.7889 0.991 0.928,1.06 984 9799
483 Acute bronchitis and bronchiolitis respiratory Both 0.863 1.0 0.964,1.04 2615 24227 0.8318 1.0 0.964,1.05 2594 24091
495 Asthma respiratory Both 0.1346 0.98 0.954,1.01 6951 27725 0.2773 1.03 0.974,1.1 1243 12395
495.1 Chronic obstructive asthma respiratory Both 0.5546 0.967 0.865,1.08 341 3403 0.3758 1.13 0.864,1.47 59 590
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.4236 1.11 0.855,1.45 60 592 0.3758 1.13 0.864,1.47 59 590
495.2 Asthma with exacerbation respiratory Both 0.2858 1.03 0.974,1.09 1251 12442 0.2773 1.03 0.974,1.1 1243 12395
496 Chronic airway obstruction respiratory Both 0.3373 0.984 0.953,1.02 4444 23893 0.9863 1.0 0.906,1.11 431 4287
496.1 Emphysema respiratory Both 0.7621 0.993 0.946,1.04 1831 16712 0.8954 0.997 0.95,1.05 1814 16570
496.2 Chronic bronchitis respiratory Both 0.1849 0.976 0.941,1.01 3357 22668 0.6918 0.992 0.955,1.03 3013 21535
496.21 Obstructive chronic bronchitis respiratory Both 0.6324 0.991 0.954,1.03 3040 21701 0.6918 0.992 0.955,1.03 3013 21535
496.3 Bronchiectasis respiratory Both 0.9661 1.0 0.908,1.11 435 4329 0.9863 1.0 0.906,1.11 431 4287
497 Bronchitis respiratory Both 0.6223 0.987 0.935,1.04 1481 14700 0.6471 0.988 0.936,1.04 1473 14630
498 Acute bronchospasm respiratory Both 0.139 0.923 0.83,1.03 376 3745 0.1596 0.926 0.833,1.03 375 3731
499 Cystic fibrosis respiratory Both 0.9036 0.989 0.82,1.19 116 1160 0.8933 0.987 0.819,1.19 116 1156
500 Lung disease due to external agents respiratory Both 0.6281 1.02 0.928,1.13 428 4273 0.1641 1.2 0.928,1.56 65 636
500.1 Extrinsic allergic alveolitis respiratory Both 0.8511 1.02 0.821,1.27 81 810 0.7194 1.04 0.836,1.3 80 803
500.2 Pneumoconiosis respiratory Both 0.177 1.19 0.923,1.55 65 640 0.1641 1.2 0.928,1.56 65 636
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.3483 0.958 0.875,1.05 514 5078 0.3083 0.954 0.871,1.04 508 5028
502 Postinflammatory pulmonary fibrosis respiratory Both 0.08511 1.08 0.99,1.17 623 6192 0.0955 1.07 0.988,1.17 614 6133
503 Pulmonary congestion and hypostasis respiratory Both 0.2317 0.954 0.882,1.03 690 6875 0.26 0.956 0.885,1.03 685 6815
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.3373 1.05 0.951,1.16 447 4454 0.3999 1.06 0.927,1.21 244 2432
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.3251 1.07 0.936,1.22 247 2456 0.3999 1.06 0.927,1.21 244 2432
505 Other pulmonary inflamation or edema respiratory Both 0.1426 0.96 0.908,1.01 1352 13261 0.1489 0.96 0.908,1.01 1344 13152
506 Empyema and pneumothorax respiratory Both 0.787 1.01 0.966,1.05 2588 22332 0.8531 1.0 0.964,1.05 2559 22151
507 Pleurisy; pleural effusion respiratory Both 0.9705 1.0 0.959,1.04 2415 21828 0.9528 0.999 0.957,1.04 2389 21669
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.4819 1.02 0.971,1.06 2005 19256 0.6095 1.01 0.966,1.06 1987 19105
509 Respiratory failure, insufficiency, arrest respiratory Both 0.7328 1.01 0.969,1.05 3044 23898 0.456 0.974 0.908,1.04 842 8396
509.1 Respiratory failure respiratory Both 0.975 1.0 0.949,1.06 1466 14560 0.9016 0.997 0.944,1.05 1457 14444
509.2 Respiratory insufficiency respiratory Both 0.04365 1.07 1.0,1.15 928 9238 0.0631 1.07 0.997,1.14 920 9160
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.8375 1.01 0.954,1.06 1500 14783 0.9036 1.0 0.951,1.06 1489 14642
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.4797 0.975 0.91,1.05 848 8472 0.456 0.974 0.908,1.04 842 8396
510 Other diseases of lung respiratory Both 0.4645 0.988 0.958,1.02 4671 30168 0.3062 1.1 0.917,1.32 127 1262
510.2 Lung transplant respiratory Both 0.3076 1.1 0.917,1.32 128 1274 0.3062 1.1 0.917,1.32 127 1262
512 Other symptoms of respiratory system respiratory Both 0.8279 1.0 0.982,1.02 14878 23476 0.5284 1.01 0.983,1.03 8589 23303
512.1 Wheezing respiratory Both 0.5585 0.981 0.922,1.04 1071 10626 0.5572 0.981 0.922,1.04 1064 10565
512.2 Painful respiration respiratory Both 0.1038 1.04 0.992,1.09 1765 17029 0.1 1.04 0.992,1.1 1756 16932
512.3 Abnormal chest sounds respiratory Both 0.8017 0.982 0.855,1.13 229 2261 0.7907 0.981 0.853,1.13 226 2238
512.7 Shortness of breath respiratory Both 0.861 1.0 0.977,1.03 7928 23452 0.9247 1.0 0.975,1.03 7869 23288
512.8 Cough respiratory Both 0.955 1.0 0.974,1.03 7280 23469 0.9977 1.0 0.974,1.03 7226 23305
512.9 Other dyspnea respiratory Both 0.4276 1.01 0.985,1.04 8658 23467 0.5284 1.01 0.983,1.03 8589 23303
513 Respiratory abnormalities respiratory Both 0.8892 1.0 0.979,1.02 10231 28110 0.2793 0.925 0.803,1.07 201 2031
513.3 Hypoventilation respiratory Both 0.3214 0.959 0.884,1.04 618 6146 0.4018 0.935 0.798,1.09 167 1637
513.31 Apnea respiratory Both 0.3673 0.949 0.846,1.06 314 3136 0.2871 0.94 0.838,1.05 311 3114
513.32 Orthopnea respiratory Both 0.4102 0.936 0.799,1.1 167 1662 0.4018 0.935 0.798,1.09 167 1637
513.4 Hyperventilation respiratory Both 0.7379 0.983 0.892,1.08 440 4383 0.7691 0.985 0.894,1.09 435 4359
513.8 Disorders of diaphragm respiratory Both 0.2793 0.926 0.804,1.06 206 2053 0.2793 0.925 0.803,1.07 201 2031
514 Abnormal findings examination of lungs respiratory Both 0.9572 0.999 0.968,1.03 4486 29229 0.151 0.97 0.931,1.01 2450 22510
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.5082 1.05 0.907,1.22 193 1914 0.526 1.05 0.905,1.22 192 1899
514.2 Solitary pulmonary nodule respiratory Both 0.2259 0.975 0.935,1.02 2489 22668 0.151 0.97 0.931,1.01 2450 22510
516 Abnormal sputum respiratory Both 0.2371 1.05 0.966,1.15 565 5640 0.6486 1.02 0.929,1.13 465 4676
516.1 Hemoptysis respiratory Both 0.6209 1.02 0.931,1.13 473 4720 0.6486 1.02 0.929,1.13 465 4676
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.6427 1.01 0.978,1.04 5153 32053 0.9183 0.998 0.966,1.03 4002 28986
519.1 Tracheostomy complications respiratory Both 0.4111 0.937 0.803,1.09 176 1760 0.399 0.936 0.802,1.09 176 1746
519.2 Respiratory complications respiratory Both 0.7362 1.02 0.915,1.13 370 3696 0.7031 1.02 0.917,1.14 369 3658
519.8 Other diseases of respiratory system, NEC respiratory Both 0.3311 1.03 0.966,1.11 887 8857 0.4083 1.03 0.961,1.1 881 8795
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.9441 1.0 0.969,1.03 4043 29199 0.9183 0.998 0.966,1.03 4002 28986
520 Disorders of tooth development digestive Both 0.2649 1.07 0.95,1.21 291 2900 0.7534 1.02 0.879,1.2 172 1681
520.1 Hereditary disturbances in tooth structure digestive Both 0.3846 1.08 0.905,1.3 131 1301 0.3733 1.09 0.906,1.3 131 1293
520.2 Disturbances in tooth eruption digestive Both 0.7816 1.02 0.876,1.19 172 1693 0.7534 1.02 0.879,1.2 172 1681
521 Diseases of hard tissues of teeth digestive Both 0.4898 0.974 0.903,1.05 719 7167 0.7568 0.988 0.913,1.07 666 6649
521.1 Dental caries digestive Both 0.7261 0.986 0.912,1.07 673 6709 0.7568 0.988 0.913,1.07 666 6649
522 Diseases of pulp and periapical tissues digestive Both 0.2084 0.937 0.847,1.04 408 4067 0.1 0.912 0.816,1.02 341 3384
522.5 Periapical abscess digestive Both 0.09333 0.91 0.815,1.02 341 3404 0.1 0.912 0.816,1.02 341 3384
523 Gingival and periodontal diseases digestive Both 0.1349 0.937 0.86,1.02 569 5690 0.2911 0.896 0.732,1.1 102 1012
523.1 Gingivitis digestive Both 0.3373 0.915 0.765,1.1 117 1163 0.3388 0.916 0.765,1.1 117 1156
523.3 Periodontitis (acute or chronic) digestive Both 0.456 0.956 0.848,1.08 294 2940 0.2911 0.896 0.732,1.1 102 1012
523.31 Acute periodontitis digestive Both 0.7031 0.975 0.856,1.11 251 2510 0.7834 0.982 0.861,1.12 249 2493
523.32 Chronic periodontitis digestive Both 0.2793 0.895 0.732,1.09 103 1030 0.2911 0.896 0.732,1.1 102 1012
524 Dentofacial anomalies, including malocclusion digestive Both 0.0955 1.11 0.982,1.25 308 3080 0.7691 1.02 0.88,1.19 185 1844
524.3 Anomalies of tooth position/malocclusion digestive Both 0.798 1.02 0.878,1.18 186 1856 0.7691 1.02 0.88,1.19 185 1844
525 Other diseases of the teeth and supporting structures digestive Both 0.5808 1.02 0.951,1.09 853 8530 0.08128 1.11 0.987,1.25 315 3155
525.1 Loss of teeth or edentulism digestive Both 0.07943 1.11 0.988,1.25 318 3178 0.08128 1.11 0.987,1.25 315 3155
526 Diseases of the jaws digestive Both 0.6053 0.988 0.945,1.03 2140 21162 0.9484 0.997 0.9,1.1 399 3957
526.1 Cysts of the jaws digestive Both 0.2924 0.928 0.808,1.07 213 2123 0.2312 0.918 0.799,1.06 211 2104
526.3 Anomalies of jaw size/symmetry digestive Both 0.3556 0.935 0.811,1.08 206 2052 0.3837 0.939 0.814,1.08 205 2038
526.4 Temporomandibular joint disorders digestive Both 0.2844 0.967 0.911,1.03 1178 11779 0.863 0.993 0.912,1.08 598 5979
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.5248 0.978 0.914,1.05 941 9410 0.4966 0.977 0.913,1.05 938 9386
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.871 0.993 0.912,1.08 600 5993 0.863 0.993 0.912,1.08 598 5979
526.5 Inflammatory conditions of jaw digestive Both 0.7889 1.02 0.893,1.16 242 2405 0.7621 1.02 0.895,1.16 242 2385
526.9 Jaw disease NOS digestive Both 0.955 0.997 0.901,1.1 399 3982 0.9484 0.997 0.9,1.1 399 3957
527 Diseases of the salivary glands digestive Both 0.5483 0.983 0.93,1.04 1362 13604 0.8299 0.984 0.851,1.14 195 1949
527.2 Sialoadenitis digestive Both 0.8892 1.01 0.898,1.13 320 3200 0.9333 1.0 0.895,1.13 318 3178
527.7 Disturbance of salivary secretion digestive Both 0.5598 0.978 0.906,1.06 715 7141 0.5598 0.977 0.905,1.06 711 7077
527.8 Other specified diseases of the salivary glands digestive Both 0.826 0.984 0.851,1.14 196 1960 0.8299 0.984 0.851,1.14 195 1949
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.798 1.01 0.962,1.05 2077 20750 0.9078 0.989 0.826,1.19 130 1310
528.1 Stomatitis and mucositis digestive Both 0.5598 0.974 0.892,1.06 536 5360 0.05248 0.861 0.739,1.0 168 1688
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.857 1.01 0.863,1.19 165 1650 0.8913 1.01 0.86,1.19 164 1640
528.12 Oral aphthae digestive Both 0.04169 0.855 0.735,0.994 170 1700 0.05248 0.861 0.739,1.0 168 1688
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.975 0.998 0.859,1.16 185 1837 0.9931 1.0 0.861,1.16 184 1817
528.4 Cysts of oral soft tissues digestive Both 0.2223 1.13 0.927,1.38 110 1096 0.09772 1.24 0.962,1.59 68 675
528.41 Cyst of the salivary gland digestive Both 0.0955 1.24 0.963,1.59 68 679 0.09772 1.24 0.962,1.59 68 675
528.5 Diseases of lips digestive Both 0.6622 0.975 0.873,1.09 334 3340 0.5984 0.97 0.868,1.09 329 3323
528.6 Leukoplakia of oral mucosa digestive Both 0.2944 1.11 0.915,1.34 113 1120 0.2958 1.11 0.914,1.34 113 1113
528.7 Sialolithiasis digestive Both 0.871 0.985 0.823,1.18 132 1320 0.9078 0.989 0.826,1.19 130 1310
529 Diseases and other conditions of the tongue digestive Both 0.1714 1.06 0.973,1.16 541 5402 0.3388 1.09 0.913,1.3 136 1340
529.1 Glossitis digestive Both 0.07079 1.21 0.984,1.49 99 982 0.07586 1.21 0.98,1.48 98 976
529.6 Glossodynia digestive Both 0.3784 1.08 0.907,1.29 136 1355 0.3388 1.09 0.913,1.3 136 1340
530 Diseases of esophagus digestive Both 0.8222 0.998 0.976,1.02 13874 23034 0.4645 1.02 0.963,1.09 1184 11882
530.1 Esophagitis, GERD and related diseases digestive Both 0.8318 0.998 0.976,1.02 13419 23031 0.02884 0.832 0.706,0.981 145 1432
530.11 GERD digestive Both 0.9441 0.999 0.978,1.02 13059 23031 0.9141 0.999 0.977,1.02 12970 22863
530.12 Ulcer of esophagus digestive Both 0.7129 1.02 0.907,1.15 298 2973 0.7362 1.02 0.905,1.15 296 2954
530.13 Barrett's esophagus digestive Both 0.4345 1.03 0.951,1.12 609 6080 0.4634 1.03 0.949,1.12 603 6019
530.14 Reflux esophagitis digestive Both 0.6531 0.988 0.936,1.04 1483 14213 0.695 0.989 0.937,1.04 1468 14128
530.15 Eosinophilic esophagitis digestive Both 0.0263 0.83 0.703,0.978 145 1441 0.02884 0.832 0.706,0.981 145 1432
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.3076 1.05 0.956,1.15 475 4742 0.3214 1.05 0.955,1.15 473 4697
530.3 Stricture and stenosis of esophagus digestive Both 0.3365 1.04 0.962,1.12 752 7474 0.3622 1.04 0.96,1.12 745 7417
530.5 Disorders of esophageal motility digestive Both 0.5929 0.974 0.882,1.07 434 4326 0.6194 0.975 0.884,1.08 429 4300
530.6 Diverticulum of esophagus, acquired digestive Both 0.8453 1.02 0.846,1.23 121 1181 0.826 1.02 0.849,1.23 121 1171
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.2323 0.868 0.688,1.09 70 700 0.2393 0.869 0.688,1.1 69 692
530.9 Heartburn digestive Both 0.4009 1.03 0.966,1.09 1198 11946 0.4645 1.02 0.963,1.09 1184 11882
531 Peptic ulcer (excl. esophageal) digestive Both 0.2032 1.03 0.982,1.09 1608 16066 0.9954 0.999 0.823,1.21 114 1136
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.9954 1.0 0.891,1.12 311 3103 0.912 0.993 0.885,1.12 307 3080
531.2 Gastric ulcer digestive Both 0.1259 1.06 0.985,1.13 884 8834 0.1483 1.05 0.982,1.13 873 8778
531.3 Duodenal ulcer digestive Both 0.695 1.02 0.917,1.14 362 3613 0.7551 1.02 0.912,1.14 355 3582
531.4 Peptic ulcer, site unspecified digestive Both 0.2234 1.05 0.969,1.14 632 6313 0.2723 1.05 0.964,1.14 627 6273
531.5 Gastrojejunal ulcer digestive Both 0.975 0.997 0.822,1.21 115 1143 0.9954 0.999 0.823,1.21 114 1136
532 Dysphagia digestive Both 0.7816 1.0 0.972,1.04 4457 22190 0.8166 1.0 0.972,1.04 4434 22033
535 Gastritis and duodenitis digestive Both 0.01905 1.06 1.01,1.1 2129 21208 0.3388 1.03 0.967,1.1 977 9775
535.1 Acute gastritis digestive Both 0.05754 1.07 0.998,1.15 814 8139 0.06457 1.07 0.996,1.15 808 8093
535.2 Atrophic gastritis digestive Both 0.309 1.07 0.939,1.22 250 2500 0.2897 1.07 0.941,1.23 247 2484
535.6 Duodenitis digestive Both 0.3041 1.07 0.942,1.21 265 2650 0.2382 1.08 0.951,1.22 263 2625
535.8 Other specified gastritis digestive Both 0.5082 1.03 0.941,1.13 497 4964 0.413 1.04 0.947,1.14 493 4929
535.9 Gastritis and duodenitis, NOS digestive Both 0.3365 1.03 0.967,1.1 985 9835 0.3388 1.03 0.967,1.1 977 9775
536 Disorders of function of stomach digestive Both 0.3251 1.02 0.979,1.07 2251 22311 0.1146 1.04 0.99,1.1 1685 16743
536.3 Gastroparesis digestive Both 0.3069 0.953 0.869,1.05 489 4876 0.2992 0.952 0.868,1.04 488 4851
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.7621 1.02 0.908,1.14 334 3331 0.8974 1.01 0.898,1.13 329 3307
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.0871 1.04 0.994,1.1 1699 16834 0.1146 1.04 0.99,1.1 1685 16743
537 Other disorders of stomach and duodenum digestive Both 0.9099 1.0 0.961,1.05 2357 23199 0.4943 0.939 0.785,1.12 126 1260
537.1 Lesions of stomach and duodenum digestive Both 0.5117 0.942 0.788,1.13 128 1271 0.4943 0.939 0.785,1.12 126 1260
539 Bariatric surgery digestive Both 0.9727 0.999 0.939,1.06 1118 11180 0.955 0.998 0.938,1.06 1115 11150
540 Appendiceal conditions digestive Both 0.2109 0.936 0.844,1.04 399 3990 0.5458 0.964 0.854,1.09 292 2908
540.1 Appendicitis digestive Both 0.3733 0.951 0.852,1.06 349 3490 0.5458 0.964 0.854,1.09 292 2908
540.11 Acute appendicitis digestive Both 0.471 0.957 0.848,1.08 293 2930 0.5458 0.964 0.854,1.09 292 2908
550 Abdominal hernia digestive Both 0.8017 1.0 0.975,1.03 5517 31191 0.7161 1.01 0.95,1.08 1088 10922
550.1 Inguinal hernia digestive Both 0.8974 0.996 0.944,1.05 1427 13556 0.9817 0.999 0.946,1.06 1395 13384
550.2 Diaphragmatic hernia digestive Both 0.2773 1.02 0.981,1.07 2290 21266 0.2871 1.02 0.98,1.07 2273 21142
550.3 Femoral hernia digestive Both 0.3972 0.922 0.763,1.11 109 1082 0.4036 0.923 0.764,1.11 109 1078
550.4 Umbilical hernia digestive Both 0.1888 0.959 0.902,1.02 1053 10514 0.2065 0.961 0.903,1.02 1046 10419
550.5 Ventral hernia digestive Both 0.7311 0.992 0.945,1.04 1826 18190 0.7228 0.991 0.945,1.04 1808 18069
550.6 Incisional hernia digestive Both 0.6622 1.01 0.953,1.08 1101 10999 0.7161 1.01 0.95,1.08 1088 10922
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.865 0.995 0.939,1.05 1275 12527 0.5741 0.972 0.882,1.07 434 4337
555.1 Regional enteritis digestive Both 0.778 1.01 0.938,1.09 775 7701 0.7745 1.01 0.938,1.09 774 7652
555.2 Ulcerative colitis digestive Both 0.5888 0.98 0.909,1.06 768 7591 0.5741 0.972 0.882,1.07 434 4337
555.21 Ulcerative colitis (chronic) digestive Both 0.526 0.969 0.879,1.07 438 4361 0.5741 0.972 0.882,1.07 434 4337
556 Ulceration of the lower GI tract digestive Both 0.2183 0.943 0.859,1.04 473 4719 0.3673 0.928 0.788,1.09 151 1483
556.1 Ulceration of intestine digestive Both 0.3926 0.957 0.866,1.06 412 4099 0.3673 0.928 0.788,1.09 151 1483
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.3311 0.923 0.785,1.09 152 1496 0.3673 0.928 0.788,1.09 151 1483
557 Intestinal malabsorption (non-celiac) digestive Both 0.8185 1.01 0.951,1.07 1306 12565 0.09333 0.902 0.801,1.02 304 3040
557.1 Celiac disease digestive Both 0.08511 0.901 0.799,1.01 305 3050 0.09333 0.902 0.801,1.02 304 3040
558 Noninfectious gastroenteritis digestive Both 0.9441 1.0 0.962,1.04 2706 20417 0.9354 1.0 0.962,1.04 2686 20286
559 Ileostomy status digestive Both 0.5 1.03 0.953,1.1 773 7702 0.3828 1.03 0.959,1.11 765 7649
560 Intestinal obstruction without mention of hernia digestive Both 0.08913 1.04 0.995,1.08 2580 20303 0.1439 1.04 0.986,1.1 1472 14285
560.1 Paralytic ileus digestive Both 0.2344 1.03 0.979,1.09 1429 13524 0.2483 1.03 0.978,1.09 1409 13407
560.2 Impaction of intestine digestive Both 0.9268 0.994 0.872,1.13 257 2499 0.9354 0.995 0.873,1.13 256 2483
560.3 Peritoneal or intestinal adhesions digestive Both 0.5309 1.04 0.917,1.18 261 2599 0.5333 1.04 0.916,1.19 258 2581
560.4 Other intestinal obstruction digestive Both 0.1455 1.04 0.986,1.1 1489 14381 0.1439 1.04 0.986,1.1 1472 14285
561 Symptoms involving digestive system digestive Both 0.6442 0.994 0.968,1.02 7750 22039 0.04074 0.956 0.916,0.998 2341 18879
561.1 Diarrhea digestive Both 0.9333 0.999 0.97,1.03 5986 22042 0.9419 0.999 0.97,1.03 5937 21891
561.2 Flatulence digestive Both 0.05495 0.959 0.919,1.0 2358 18995 0.04074 0.956 0.916,0.998 2341 18879
562 Diverticulosis and diverticulitis digestive Both 0.4159 0.987 0.956,1.02 5014 18500 0.335 0.972 0.918,1.03 1285 12166
562.1 Diverticulosis digestive Both 0.5093 0.989 0.958,1.02 4973 18448 0.5105 0.989 0.958,1.02 4931 18320
562.2 Diverticulitis digestive Both 0.4102 0.976 0.922,1.03 1292 12242 0.335 0.972 0.918,1.03 1285 12166
563 Constipation digestive Both 0.9183 1.0 0.972,1.03 5639 22004 0.9462 1.0 0.972,1.03 5597 21854
564 Functional digestive disorders digestive Both 0.9268 0.999 0.975,1.02 9553 22037 0.8892 0.996 0.948,1.05 1751 16425
564.1 Irritable Bowel Syndrome digestive Both 0.4989 0.986 0.946,1.03 2751 17147 0.5093 0.986 0.947,1.03 2736 17058
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.5636 0.987 0.946,1.03 2348 18710 0.6442 0.99 0.948,1.03 2328 18583
564.9 Personal history of diseases of digestive system digestive Both 0.8433 0.995 0.947,1.05 1762 16521 0.8892 0.996 0.948,1.05 1751 16425
565 Anal and rectal conditions digestive Both 0.7603 0.994 0.954,1.04 2533 24500 0.9226 1.0 0.938,1.07 921 9242
565.1 Anal and rectal polyp digestive Both 0.8913 1.0 0.939,1.07 932 9300 0.9226 1.0 0.938,1.07 921 9242
567 Peritonitis and retroperitoneal infections digestive Both 0.8414 0.994 0.936,1.06 1149 11482 0.8472 0.994 0.936,1.06 1139 11412
568 Other disorders of peritoneum digestive Both 0.7568 0.992 0.94,1.05 1452 14494 0.9661 1.0 0.941,1.07 1060 10688
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.929 0.997 0.938,1.06 1076 10752 0.9661 1.0 0.941,1.07 1060 10688
569 Other disorders of intestine digestive Both 0.3837 0.988 0.961,1.02 6343 29512 0.869 1.0 0.947,1.07 1194 11978
569.1 Toxic gastroenteritis and colitis digestive Both 0.4227 1.06 0.926,1.2 251 2510 0.3936 1.06 0.928,1.21 245 2489
569.2 Gastrointestinal complications digestive Both 0.9772 1.0 0.944,1.06 1206 12058 0.869 1.0 0.947,1.07 1194 11978
571 Chronic liver disease and cirrhosis digestive Both 0.3631 0.984 0.95,1.02 3603 27394 0.5984 1.03 0.931,1.13 439 4358
571.5 Other chronic nonalcoholic liver disease digestive Both 0.3243 0.982 0.948,1.02 3388 27100 0.1816 0.951 0.883,1.02 773 7746
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.1754 0.951 0.883,1.02 781 7802 0.1816 0.951 0.883,1.02 773 7746
571.6 Primary biliary cirrhosis digestive Both 0.2483 1.11 0.931,1.32 146 1460 0.2512 1.11 0.931,1.32 146 1455
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.857 1.01 0.935,1.08 749 7472 0.5984 1.03 0.931,1.13 439 4358
571.81 Portal hypertension digestive Both 0.5848 1.03 0.932,1.13 441 4400 0.5984 1.03 0.931,1.13 439 4358
572 Ascites (non malignant) digestive Both 0.1667 0.967 0.923,1.01 1884 18805 0.1786 0.968 0.923,1.01 1864 18688
573 Other disorders of liver digestive Both 0.2286 0.981 0.95,1.01 4460 28151 0.6368 0.991 0.956,1.03 3313 27863
573.1 Chronic passive congestion of liver digestive Both 0.7709 1.03 0.843,1.26 100 991 0.6561 1.05 0.855,1.28 98 981
573.2 Liver replaced by transplant digestive Both 0.6516 0.97 0.848,1.11 227 2268 0.6561 0.97 0.848,1.11 225 2252
573.3 Hepatomegaly digestive Both 0.6855 1.02 0.914,1.15 337 3368 0.7447 1.02 0.91,1.14 334 3354
573.4 Acute and subacute necrosis of liver digestive Both 0.955 1.0 0.885,1.14 258 2580 0.9795 0.998 0.88,1.13 257 2560
573.5 Jaundice (not of newborn) digestive Both 0.6026 1.02 0.947,1.1 758 7555 0.6194 1.02 0.946,1.1 752 7493
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.5623 0.986 0.942,1.03 1973 19683 0.4721 0.983 0.939,1.03 1947 19541
573.7 Abnormal results of function study of liver digestive Both 0.3917 0.981 0.938,1.03 2110 21014 0.3443 0.979 0.936,1.02 2092 20863
573.9 Abnormal serum enzyme levels digestive Both 0.7079 0.993 0.958,1.03 3345 28043 0.6368 0.991 0.956,1.03 3313 27863
574 Cholelithiasis and cholecystitis digestive Both 0.2871 1.02 0.982,1.06 2610 25589 0.7925 0.989 0.914,1.07 665 6613
574.1 Cholelithiasis digestive Both 0.4808 1.02 0.973,1.06 2391 23829 0.05129 1.1 0.999,1.22 443 4411
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.1262 0.908 0.802,1.03 260 2580 0.1309 0.909 0.803,1.03 259 2561
574.12 Cholelithiasis with other cholecystitis digestive Both 0.05248 1.1 0.999,1.22 444 4434 0.05129 1.1 0.999,1.22 443 4411
574.2 Calculus of bile duct digestive Both 0.9247 0.996 0.922,1.08 696 6939 0.9594 0.998 0.924,1.08 696 6904
574.3 Cholecystitis without cholelithiasis digestive Both 0.7798 0.989 0.914,1.07 667 6662 0.7925 0.989 0.914,1.07 665 6613
575 Other biliary tract disease digestive Both 0.8551 1.0 0.957,1.05 1868 18668 0.1285 0.892 0.769,1.03 186 1862
575.1 Cholangitis digestive Both 0.9397 1.0 0.895,1.13 310 3089 0.9683 1.0 0.892,1.13 308 3060
575.2 Obstruction of bile duct digestive Both 0.6577 1.02 0.933,1.12 530 5291 0.6902 1.02 0.931,1.11 526 5241
575.6 Cholesterolosis of gallbladder digestive Both 0.2838 0.915 0.778,1.08 168 1680 0.26 0.911 0.774,1.07 166 1668
575.7 Other disorders of gallbladder digestive Both 0.2612 1.04 0.969,1.12 773 7719 0.2173 1.05 0.973,1.13 767 7677
575.8 Other disorders of biliary tract digestive Both 0.912 1.0 0.94,1.07 996 9950 0.9886 1.0 0.937,1.07 989 9875
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.125 0.892 0.77,1.03 188 1880 0.1285 0.892 0.769,1.03 186 1862
577 Diseases of pancreas digestive Both 0.4742 0.983 0.937,1.03 1842 18379 0.6026 1.03 0.931,1.13 460 4511
577.1 Acute pancreatitis digestive Both 0.02239 0.927 0.869,0.989 967 9651 0.02512 0.929 0.87,0.991 962 9582
577.2 Chronic pancreatitis digestive Both 0.6339 0.976 0.881,1.08 396 3955 0.6577 0.977 0.883,1.08 395 3924
577.3 Cyst and pseudocyst of pancreas digestive Both 0.6699 1.02 0.927,1.12 462 4557 0.6026 1.03 0.931,1.13 460 4511
578 Gastrointestinal hemorrhage digestive Both 0.3926 1.02 0.981,1.05 3572 30460 0.6887 1.01 0.954,1.07 1229 12181
578.1 Hematemesis digestive Both 0.8933 0.993 0.894,1.1 383 3821 0.8185 0.988 0.889,1.1 380 3789
578.2 Blood in stool digestive Both 0.8453 0.996 0.952,1.04 2156 21196 0.7311 0.992 0.949,1.04 2136 21061
578.8 Hemorrhage of rectum and anus digestive Both 0.6026 1.01 0.964,1.07 1718 17070 0.6486 1.01 0.962,1.06 1703 16977
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.6668 1.01 0.955,1.07 1238 12280 0.6887 1.01 0.954,1.07 1229 12181
579 Other symptoms involving abdomen and pelvis digestive Both 0.2466 1.02 0.986,1.06 3750 28690 0.5224 1.02 0.957,1.09 985 9825
579.2 Splenomegaly digestive Both 0.9397 1.0 0.923,1.09 593 5923 0.9616 0.998 0.918,1.09 587 5869
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.3606 1.03 0.966,1.1 998 9882 0.5224 1.02 0.957,1.09 985 9825
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.3715 1.03 0.969,1.09 1264 12626 0.881 0.991 0.874,1.12 273 2739
580.1 Glomerulonephritis genitourinary Both 0.9886 0.999 0.89,1.12 324 3228 0.4887 1.05 0.915,1.21 232 2285
580.11 Proliferative glomerulonephritis genitourinary Both 0.9397 1.01 0.83,1.22 114 1140 0.9528 1.01 0.828,1.22 114 1136
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.514 0.928 0.741,1.16 92 905 0.4898 0.924 0.737,1.16 92 899
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.5035 1.05 0.913,1.2 232 2298 0.4887 1.05 0.915,1.21 232 2285
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.6918 1.03 0.879,1.21 167 1670 0.6982 1.03 0.879,1.21 167 1664
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.3548 1.03 0.965,1.1 943 9430 0.5495 1.03 0.937,1.13 495 4962
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.3999 1.04 0.952,1.13 554 5535 0.3811 1.04 0.953,1.13 553 5488
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.5012 1.03 0.941,1.13 500 4995 0.5495 1.03 0.937,1.13 495 4962
580.4 Renal sclerosis, NOS genitourinary Both 0.8017 0.984 0.869,1.11 275 2750 0.881 0.991 0.874,1.12 273 2739
585 Renal failure genitourinary Both 0.9638 0.999 0.971,1.03 5756 27307 0.8892 1.01 0.937,1.08 844 8307
585.1 Acute renal failure genitourinary Both 0.8356 1.0 0.968,1.04 3278 22851 0.9057 1.0 0.966,1.04 3247 22682
585.2 Renal failure NOS genitourinary Both 0.3381 1.04 0.961,1.12 688 6872 0.335 1.04 0.961,1.12 683 6817
585.3 Chronic renal failure [CKD] genitourinary Both 0.5546 0.99 0.958,1.02 4216 24655 0.7278 1.01 0.938,1.1 700 6979
585.31 Renal dialysis genitourinary Both 0.8974 1.01 0.921,1.1 543 5430 0.9247 1.0 0.92,1.1 541 5386
585.32 End stage renal disease genitourinary Both 0.8831 1.01 0.934,1.08 773 7730 0.9661 1.0 0.93,1.08 769 7673
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.3673 0.98 0.938,1.02 2272 17155 0.4385 0.983 0.94,1.03 2250 17032
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.6237 1.02 0.943,1.1 707 7038 0.7278 1.01 0.938,1.1 700 6979
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.9099 1.0 0.936,1.08 851 8381 0.8892 1.01 0.937,1.08 844 8307
586 Other disorders of the kidney and ureters genitourinary Both 0.6209 1.01 0.979,1.04 6202 28774 0.4732 1.02 0.967,1.07 1515 14553
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.8453 1.01 0.896,1.14 284 2825 0.798 1.03 0.843,1.25 112 1115
586.11 Small kidney genitourinary Both 0.7889 0.978 0.832,1.15 165 1642 0.811 0.98 0.833,1.15 164 1632
586.12 Vesicoureteral reflux genitourinary Both 0.8241 1.02 0.84,1.24 112 1120 0.798 1.03 0.843,1.25 112 1115
586.2 Cyst of kidney, acquired genitourinary Both 0.8279 0.993 0.935,1.06 1170 11069 0.6577 0.986 0.928,1.05 1150 10976
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.8128 0.98 0.832,1.16 148 1470 0.867 0.986 0.836,1.16 145 1457
586.4 Stricture/obstruction of ureter genitourinary Both 0.547 1.02 0.964,1.07 1536 14675 0.4732 1.02 0.967,1.07 1515 14553
587 Kidney replaced by transpant genitourinary Both 0.867 0.993 0.914,1.08 612 6120 0.7447 0.986 0.908,1.07 608 6068
588 Disorders resulting from impaired renal function genitourinary Both 0.2307 1.05 0.97,1.13 701 7004 0.4786 1.03 0.944,1.13 523 5211
588.1 Renal osteodystrophy genitourinary Both 0.7447 0.977 0.851,1.12 227 2267 0.6252 0.966 0.841,1.11 224 2249
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.4355 1.04 0.947,1.13 525 5241 0.4786 1.03 0.944,1.13 523 5211
589 Abnormal results of function study of kidney genitourinary Both 0.2051 1.05 0.975,1.12 840 8370 0.2188 1.05 0.974,1.12 834 8311
590 Pyelonephritis genitourinary Both 0.7907 1.01 0.949,1.07 1161 11597 0.8185 1.01 0.948,1.07 1154 11553
591 Urinary tract infection genitourinary Both 0.5272 0.992 0.967,1.02 8020 27291 0.6353 0.994 0.969,1.02 7966 27104
592 Cystitis and urethritis genitourinary Both 0.2673 0.976 0.934,1.02 2264 19423 0.0955 0.864 0.727,1.03 140 1420
592.1 Cystitis genitourinary Both 0.3027 0.977 0.934,1.02 2149 18531 0.05888 0.901 0.809,1.0 353 3535
592.11 Acute cystitis genitourinary Both 0.7638 0.991 0.935,1.05 1256 12111 0.7278 0.99 0.934,1.05 1253 12070
592.12 Chronic cystitis genitourinary Both 0.1862 1.11 0.953,1.28 199 1972 0.1766 1.11 0.955,1.29 199 1967
592.13 Chronic interstitial cystitis genitourinary Both 0.06761 0.904 0.811,1.01 354 3540 0.05888 0.901 0.809,1.0 353 3535
592.2 Urethritis and urethral syndrome genitourinary Both 0.1169 0.873 0.737,1.03 143 1430 0.0955 0.864 0.727,1.03 140 1420
593 Hematuria genitourinary Both 0.008511 0.956 0.924,0.989 3848 26566 0.04898 0.926 0.857,1.0 719 7189
593.1 Gross hematuria genitourinary Both 0.4046 0.975 0.919,1.03 1201 11351 0.414 0.976 0.919,1.04 1187 11248
593.2 Microscopic hematuria genitourinary Both 0.04266 0.924 0.855,0.997 724 7225 0.04898 0.926 0.857,1.0 719 7189
594 Urinary calculus genitourinary Both 0.2339 0.983 0.955,1.01 5516 31876 0.004898 0.841 0.746,0.949 285 2828
594.1 Calculus of kidney genitourinary Both 0.3741 0.987 0.958,1.02 5155 31730 0.4977 0.99 0.961,1.02 5116 31504
594.2 Calculus of lower urinary tract genitourinary Both 0.07413 0.901 0.804,1.01 310 3068 0.08128 0.903 0.806,1.01 309 3023
594.3 Calculus of ureter genitourinary Both 0.01622 0.928 0.873,0.986 1104 11000 0.03162 0.935 0.879,0.994 1096 10904
594.8 Renal colic genitourinary Both 0.005248 0.843 0.747,0.95 286 2851 0.004898 0.841 0.746,0.949 285 2828
595 Hydronephrosis genitourinary Both 0.2965 0.972 0.92,1.03 1410 14092 0.3483 0.974 0.922,1.03 1393 13974
596 Other disorders of bladder genitourinary Both 0.4819 0.985 0.946,1.03 2527 23338 0.5458 0.983 0.93,1.04 1357 13536
596.1 Bladder neck obstruction genitourinary Both 0.7244 1.02 0.913,1.14 333 3288 0.561 1.03 0.924,1.16 328 3247
596.5 Functional disorders of bladder genitourinary Both 0.5495 0.983 0.93,1.04 1368 13608 0.5458 0.983 0.93,1.04 1357 13536
597 Other disorders of urethra and urinary tract genitourinary Both 0.04677 1.07 1.0,1.14 1041 10322 0.004571 1.29 1.08,1.53 157 1575
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.08318 1.08 0.991,1.17 608 6024 0.0537 1.09 0.999,1.18 586 5962
597.2 Urinary complications NEC genitourinary Both 0.3614 1.03 0.963,1.11 861 8600 0.4266 1.03 0.959,1.1 847 8530
597.8 Urethral hypermobility/ISD genitourinary Both 0.006761 1.27 1.07,1.51 158 1578 0.004571 1.29 1.08,1.53 157 1575
598 Abnormal findings on examination of urine genitourinary Both 0.6668 0.987 0.932,1.05 1263 12596 0.4416 0.977 0.921,1.04 1217 12247
598.4 Other cells and casts in urine genitourinary Both 0.6934 0.958 0.774,1.19 91 906 0.6095 0.946 0.762,1.17 89 902
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.4266 0.977 0.921,1.04 1234 12317 0.4416 0.977 0.921,1.04 1217 12247
599 Other symptoms/disorders or the urinary system genitourinary Both 0.7129 1.0 0.982,1.03 11346 25364 0.2377 1.03 0.983,1.07 2327 20201
599.1 Urinary obstruction genitourinary Both 0.9616 1.0 0.921,1.09 580 5634 0.859 1.01 0.925,1.1 577 5579
599.2 Retention of urine genitourinary Both 0.912 0.998 0.966,1.03 4234 24058 0.984 1.0 0.967,1.03 4181 23941
599.3 Dysuria genitourinary Both 0.0955 0.97 0.936,1.01 3426 23180 0.1413 0.973 0.939,1.01 3402 23076
599.4 Urinary incontinence genitourinary Both 0.8472 1.0 0.971,1.04 4566 22567 0.778 1.0 0.973,1.04 4539 22474
599.5 Frequency of urination and polyuria genitourinary Both 0.5105 1.01 0.978,1.04 4277 23742 0.5834 1.01 0.976,1.04 4212 23635
599.6 Oliguria and anuria genitourinary Both 0.6622 1.02 0.932,1.12 513 5104 0.6714 1.02 0.931,1.12 506 5069
599.7 Urethral discharge genitourinary Both 0.8851 1.02 0.813,1.27 83 830 0.6471 1.05 0.839,1.33 79 825
599.8 Other symptoms involving urinary system genitourinary Both 0.8913 0.998 0.965,1.03 4366 23262 0.9226 0.998 0.966,1.03 4317 23155
599.9 Other abnormality of urination genitourinary Both 0.2218 1.03 0.984,1.07 2349 20289 0.2377 1.03 0.983,1.07 2327 20201
600 Hyperplasia of prostate genitourinary Male 0.8395 0.996 0.955,1.04 3315 9437 0.6792 0.991 0.951,1.03 3241 9437
601 Inflammatory diseases of prostate genitourinary Male 0.04266 1.08 1.0,1.15 825 7745 0.3681 1.09 0.906,1.31 117 1226
601.1 Prostatitis genitourinary Male 0.03388 1.12 1.01,1.24 378 3680 0.7031 0.957 0.761,1.2 76 757
601.11 Acute prostatitis genitourinary Male 0.2904 1.12 0.907,1.39 95 933 0.2661 1.13 0.912,1.4 94 933
601.12 Chronic prostatitis genitourinary Male 0.7031 0.957 0.761,1.2 76 757 0.7031 0.957 0.761,1.2 76 757
601.3 Orchitis and epididymitis genitourinary Male 0.3908 1.05 0.937,1.18 303 3008 0.471 1.04 0.928,1.17 294 3008
601.4 Balanoposthitis genitourinary Male 0.4207 0.925 0.765,1.12 103 1019 0.5023 0.937 0.773,1.13 102 1019
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.2612 1.11 0.927,1.32 125 1226 0.3681 1.09 0.906,1.31 117 1226
602 Other disorders of prostate genitourinary Male 0.9397 1.0 0.891,1.13 277 2673 0.7834 1.02 0.9,1.15 261 2673
603 Other disorders of testis genitourinary Male 0.2529 1.06 0.956,1.19 348 3468 0.3334 1.1 0.91,1.32 120 1247
603.1 Hydrocele genitourinary Male 0.5929 1.04 0.909,1.18 229 2281 0.6471 1.03 0.904,1.18 222 2267
603.2 Spermatocele genitourinary Male 0.2667 1.11 0.924,1.33 126 1258 0.3334 1.1 0.91,1.32 120 1247
604 Disorders of penis genitourinary Male 0.4305 1.04 0.949,1.13 536 5321 0.3908 1.07 0.916,1.25 167 1688
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.9727 1.0 0.846,1.19 130 1297 0.5715 1.05 0.879,1.26 114 1289
604.3 Peyronie's disease genitourinary Male 0.4055 1.07 0.915,1.25 171 1703 0.3908 1.07 0.916,1.25 167 1688
605 Erectile dysfunction [ED] genitourinary Male 0.06761 1.04 0.997,1.08 2844 10666 0.03311 1.05 1.0,1.09 2780 10573
608 Other disorders of male genital organs genitourinary Male 0.2028 1.04 0.981,1.1 1302 11530 0.2891 1.03 0.974,1.09 1227 11431
609 Male infertility and abnormal spermatozoa genitourinary Male 0.2564 1.07 0.955,1.19 335 3350 0.4753 1.07 0.886,1.3 115 1180
609.1 Infertility, male genitourinary Male 0.5794 1.04 0.912,1.18 242 2420 0.1125 1.21 0.955,1.54 73 781
609.11 Azoospermia and oligospermia genitourinary Male 0.0309 1.29 1.02,1.63 79 789 0.1125 1.21 0.955,1.54 73 781
609.2 Abnormal spermatozoa genitourinary Male 0.5702 1.06 0.875,1.27 119 1185 0.4753 1.07 0.886,1.3 115 1180
610 Benign mammary dysplasias genitourinary Female 0.2004 1.03 0.986,1.07 3089 13905 0.3236 1.03 0.968,1.1 1047 10149
610.1 Cystic mastopathy genitourinary Female 0.2143 1.04 0.979,1.1 1361 12011 0.2143 1.04 0.979,1.1 1361 12011
610.4 Benign neoplasm of breast genitourinary Female 0.1072 1.04 0.992,1.09 2400 13828 0.1072 1.04 0.992,1.08 2400 13828
610.8 Other specified benign mammary dysplasias genitourinary Female 0.3236 1.03 0.968,1.1 1047 10149 0.3236 1.03 0.968,1.1 1047 10149
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.4315 1.01 0.98,1.05 4952 15509 0.5188 1.01 0.973,1.05 3005 15414
611.1 Abnormal mammogram genitourinary Both 0.1671 1.03 0.989,1.06 4074 13538 0.317 1.04 0.967,1.11 962 9131
611.11 Mammographic microcalcification genitourinary Both 0.317 1.04 0.967,1.11 962 9131 0.317 1.04 0.967,1.11 962 9131
611.3 Lump or mass in breast genitourinary Both 0.5212 1.01 0.973,1.05 3011 15449 0.5188 1.01 0.973,1.05 3005 15414
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.1023 1.06 0.988,1.14 879 8768 0.597 0.935 0.729,1.2 70 676
612.1 Galactorrhea genitourinary Both 0.547 1.06 0.869,1.3 109 1083 0.547 1.06 0.869,1.3 109 1083
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.1791 1.06 0.975,1.15 672 6710 0.1879 1.06 0.974,1.15 662 6693
612.3 Congenital anomalies of breast genitourinary Both 0.597 0.935 0.729,1.2 70 676 0.597 0.935 0.729,1.2 70 676
613 Other nonmalignant breast conditions genitourinary Both 0.3837 0.983 0.946,1.02 3180 18154 0.7079 1.01 0.952,1.08 1211 11945
613.1 Inflammatory disease of breast genitourinary Both 0.3819 0.959 0.874,1.05 504 5035 0.3882 0.96 0.875,1.05 504 5031
613.5 Mastodynia genitourinary Both 0.2286 0.965 0.911,1.02 1313 12942 0.2009 0.963 0.909,1.02 1311 12931
613.7 Other signs and symptoms in breast genitourinary Both 0.7834 1.01 0.935,1.09 722 7109 0.787 1.01 0.935,1.09 722 7106
613.8 Other specified disorders of breast genitourinary Both 0.9954 1.0 0.928,1.08 800 7961 0.9931 1.0 0.928,1.08 800 7960
613.9 Breast disorder NOS genitourinary Both 0.7096 1.01 0.952,1.08 1211 11947 0.7079 1.01 0.952,1.08 1211 11945
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.1361 0.97 0.932,1.01 2990 16271 0.7816 1.02 0.869,1.2 164 1619
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.138 0.91 0.802,1.03 267 2670 0.138 0.91 0.802,1.03 267 2670
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.5888 0.972 0.877,1.08 404 4024 0.6457 0.965 0.831,1.12 198 1979
614.31 Acute inflammatory pelvic disease genitourinary Female 0.04365 0.785 0.621,0.993 74 720 0.04365 0.785 0.621,0.993 74 720
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.6266 1.04 0.886,1.22 167 1666 0.6266 1.04 0.886,1.22 167 1666
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.6457 0.965 0.831,1.12 198 1979 0.6457 0.965 0.831,1.12 198 1979
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.8974 0.988 0.821,1.19 129 1290 0.8974 0.988 0.821,1.19 129 1290
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.2301 0.974 0.933,1.02 2546 16112 0.7816 1.02 0.869,1.2 164 1619
614.51 Cervicitis and endocervicitis genitourinary Female 0.05623 0.865 0.746,1.0 197 1970 0.05623 0.865 0.746,1.0 197 1970
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.2042 0.971 0.928,1.02 2201 15690 0.2042 0.971 0.928,1.02 2201 15690
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.2535 0.889 0.726,1.09 104 1040 0.2535 0.889 0.727,1.09 104 1040
614.54 Abscess or ulceration of vulva genitourinary Female 0.7816 1.02 0.869,1.2 164 1619 0.7816 1.02 0.869,1.2 164 1619
615 Endometriosis genitourinary Female 0.8954 0.996 0.939,1.06 1298 12230 0.8954 0.996 0.939,1.06 1298 12230
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.1799 0.963 0.911,1.02 1415 13522 0.1799 0.963 0.911,1.02 1415 13522
618 Genital prolapse genitourinary Female 0.2655 1.03 0.978,1.08 1707 14626 0.6918 0.979 0.88,1.09 375 3750
618.1 Prolapse of vaginal walls genitourinary Female 0.2698 1.04 0.973,1.1 1179 11187 0.2698 1.04 0.973,1.1 1179 11187
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.04677 1.11 1.0,1.23 444 4418 0.04677 1.11 1.0,1.23 444 4418
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.7962 1.02 0.896,1.15 286 2855 0.7962 1.02 0.896,1.15 286 2855
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.6918 0.979 0.88,1.09 375 3750 0.6918 0.979 0.88,1.09 375 3750
619 Noninflammatory female genital disorders genitourinary Female 0.7413 1.01 0.972,1.04 4598 15534 0.8279 0.992 0.926,1.06 914 9082
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.2208 1.04 0.978,1.1 1262 11294 0.2208 1.04 0.978,1.1 1262 11294
619.2 Disorders of uterus, NEC genitourinary Female 0.9268 0.995 0.9,1.1 444 4435 0.9268 0.995 0.901,1.1 444 4435
619.3 Noninflammatory disorders of cervix genitourinary Female 0.4898 0.964 0.869,1.07 391 3892 0.4898 0.964 0.869,1.07 391 3892
619.4 Noninflammatory disorders of vagina genitourinary Female 0.3112 0.975 0.929,1.02 1903 15019 0.3112 0.975 0.929,1.02 1903 15019
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.8279 0.992 0.926,1.06 914 9082 0.8279 0.992 0.926,1.06 914 9082
620 Dysplasia of female genital organs genitourinary Female 0.3097 0.942 0.839,1.06 325 3234 0.3954 0.927 0.778,1.1 142 1420
620.1 Dysplasia of cervix genitourinary Female 0.3954 0.927 0.778,1.1 142 1420 0.3954 0.927 0.778,1.1 142 1420
621 Endometrial hyperplasia genitourinary Female 0.1945 0.929 0.83,1.04 334 3335 0.1945 0.929 0.83,1.04 334 3335
622 Polyp of female genital organs genitourinary Female 0.8241 1.01 0.947,1.07 1191 11723 0.9908 0.999 0.892,1.12 348 3480
622.1 Polyp of corpus uteri genitourinary Female 0.9397 0.997 0.932,1.07 949 9362 0.9397 0.997 0.932,1.07 949 9362
622.2 Mucous polyp of cervix genitourinary Female 0.9908 0.999 0.892,1.12 348 3480 0.9908 0.999 0.892,1.12 348 3480
623 Hypertrophy of female genital organs genitourinary Female 0.2312 0.949 0.871,1.03 605 6003 0.2312 0.949 0.871,1.03 605 6003
624 Symptoms involving female genital tract genitourinary Female 1.148E-4 0.88 0.824,0.939 1013 9695 0.1432 1.04 0.986,1.1 1549 12918
624.1 Dystrophy of female genital tract genitourinary Female 0.5495 0.953 0.814,1.12 168 1680 0.5495 0.953 0.814,1.12 168 1680
624.9 stress incontinence, female genitourinary Female 0.1432 1.04 0.986,1.1 1549 12918 0.1432 1.04 0.986,1.1 1549 12918
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.1671 0.976 0.944,1.01 4618 14394 0.2323 0.961 0.9,1.03 1011 10081
625.1 Dyspareunia genitourinary Female 0.2323 0.961 0.9,1.03 1011 10081 0.2323 0.961 0.9,1.03 1011 10081
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.6592 0.992 0.958,1.03 4726 13065 0.5445 1.03 0.943,1.12 630 5218
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.8147 0.995 0.957,1.04 3426 12112 0.5284 0.962 0.853,1.09 300 3000
626.11 Absent or infrequent menstruation genitourinary Female 0.3404 0.964 0.895,1.04 802 6948 0.3404 0.964 0.895,1.04 802 6948
626.12 Excessive or frequent menstruation genitourinary Female 0.881 0.996 0.945,1.05 1703 9843 0.881 0.996 0.945,1.05 1703 9843
626.13 Irregular menstrual cycle genitourinary Female 0.7161 0.99 0.937,1.05 1543 10197 0.7161 0.99 0.937,1.05 1543 10197
626.14 Irregular menstrual bleeding genitourinary Female 0.9908 1.0 0.927,1.08 777 7408 0.9908 1.0 0.927,1.08 777 7408
626.15 Infertility, female, associated with anovulation genitourinary Female 0.5284 0.962 0.853,1.09 300 3000 0.5284 0.962 0.853,1.09 300 3000
626.2 Dysmenorrhea genitourinary Female 0.5346 0.98 0.919,1.04 1116 8297 0.5346 0.98 0.919,1.04 1116 8297
626.4 Premenstrual tension syndromes genitourinary Female 0.1694 1.09 0.962,1.25 275 2741 0.1694 1.09 0.962,1.25 275 2741
626.8 Infertility, female genitourinary Female 0.5445 1.03 0.943,1.12 630 5218 0.5445 1.03 0.943,1.12 630 5218
627 Menopausal and postmenopausal disorders genitourinary Female 0.5902 0.99 0.953,1.03 3657 12296 0.6887 0.972 0.848,1.12 234 2340
627.1 Postmenopausal bleeding genitourinary Female 0.4325 0.973 0.909,1.04 957 8768 0.4325 0.973 0.909,1.04 957 8768
627.2 Symptomatic menopause genitourinary Female 0.5248 0.986 0.943,1.03 2443 11667 0.826 1.01 0.897,1.15 295 2948
627.21 Symptomatic artificial menopause genitourinary Female 0.8954 1.01 0.845,1.21 125 1241 0.8954 1.01 0.845,1.21 125 1241
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.826 1.01 0.897,1.15 295 2948 0.826 1.01 0.897,1.15 295 2948
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.695 0.985 0.911,1.06 729 7262 0.695 0.985 0.911,1.06 729 7262
627.4 Premenopausal menorrhagia genitourinary Female 0.2421 0.932 0.827,1.05 305 3020 0.2421 0.932 0.827,1.05 305 3020
627.5 Premature menopause and other ovarian failure genitourinary Female 0.6887 0.972 0.848,1.12 234 2340 0.6887 0.972 0.848,1.12 234 2340
628 Ovarian cyst genitourinary Female 0.3319 1.03 0.973,1.08 1619 11554 0.3319 1.03 0.973,1.08 1619 11554
634 Miscarriage; stillbirth pregnancy complications Female 0.4764 0.971 0.894,1.05 648 6413 0.3006 1.12 0.902,1.39 95 950
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.09333 0.883 0.764,1.02 209 2090 0.09333 0.883 0.764,1.02 209 2090
634.3 Ectopic pregnancy pregnancy complications Female 0.3006 1.12 0.902,1.39 95 950 0.3006 1.12 0.902,1.39 95 950
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.1413 0.927 0.837,1.03 414 4070 0.04266 0.862 0.747,0.995 206 2060
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.3631 0.944 0.833,1.07 272 2720 0.3631 0.944 0.833,1.07 272 2720
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.04266 0.862 0.747,0.995 206 2060 0.04266 0.862 0.747,0.995 206 2060
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.4656 0.973 0.906,1.05 855 6402 0.3162 1.15 0.873,1.52 60 600
636.1 Threatened premature labor pregnancy complications Female 0.7516 0.981 0.869,1.11 298 2980 0.7516 0.981 0.869,1.11 298 2980
636.2 Early onset of delivery pregnancy complications Female 0.4656 0.951 0.83,1.09 233 2330 0.4656 0.951 0.83,1.09 233 2330
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.2099 0.932 0.836,1.04 356 3556 0.2099 0.933 0.836,1.04 356 3556
636.8 Cervical incompetence pregnancy complications Female 0.3162 1.15 0.873,1.52 60 600 0.3162 1.15 0.873,1.52 60 600
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.3221 1.12 0.897,1.39 89 884 0.2673 1.13 0.908,1.42 87 878
638 Other high-risk pregnancy pregnancy complications Female 0.695 1.01 0.942,1.09 818 5867 0.695 1.01 0.942,1.09 818 5867
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.1303 0.925 0.837,1.02 421 4210 0.1122 0.894 0.779,1.03 215 2150
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.1122 0.894 0.779,1.03 215 2150 0.1122 0.894 0.779,1.03 215 2150
643 Excessive vomiting in pregnancy pregnancy complications Female 0.6457 0.963 0.821,1.13 181 1810 0.7295 1.04 0.827,1.31 87 870
643.1 Hyperemesis gravidarum pregnancy complications Female 0.7295 1.04 0.827,1.31 87 870 0.7295 1.04 0.827,1.31 87 870
644 Anemia during pregnancy pregnancy complications Female 0.787 0.977 0.824,1.16 154 1540 0.787 0.977 0.824,1.16 154 1540
645 Late pregnancy and failed induction pregnancy complications Female 0.9528 1.0 0.886,1.14 286 2860 0.9528 1.0 0.886,1.14 286 2860
646 Other complications of pregnancy NEC pregnancy complications Female 0.9572 0.998 0.917,1.09 622 5063 0.9572 0.998 0.917,1.09 622 5063
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.3467 1.09 0.915,1.29 152 1520 0.4786 1.06 0.905,1.24 182 1820
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.4786 1.06 0.905,1.24 182 1820 0.4786 1.06 0.905,1.24 182 1820
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.912 0.996 0.93,1.07 968 6387 0.6637 1.02 0.922,1.14 413 4130
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.6637 1.02 0.922,1.14 413 4130 0.6637 1.02 0.922,1.14 413 4130
650 Normal delivery pregnancy complications Female 0.4355 0.97 0.899,1.05 757 6412 0.4355 0.97 0.899,1.05 757 6412
651 Multiple gestation pregnancy complications Female 0.8147 0.975 0.789,1.21 100 1000 0.8147 0.975 0.789,1.2 100 1000
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.7129 0.982 0.891,1.08 461 4586 0.7129 0.982 0.891,1.08 461 4586
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.7568 1.02 0.919,1.12 443 4189 0.7568 1.02 0.919,1.12 443 4189
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.4246 1.04 0.945,1.14 482 4820 0.8511 0.984 0.834,1.16 163 1630
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.4178 0.958 0.863,1.06 402 4020 0.4178 0.958 0.863,1.06 402 4020
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.8511 0.984 0.834,1.16 163 1630 0.8511 0.984 0.834,1.16 163 1630
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.9683 0.999 0.94,1.06 1244 8117 0.9484 1.0 0.909,1.11 451 4371
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.9484 1.0 0.909,1.11 451 4371 0.9484 1.0 0.909,1.11 451 4371
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.3236 1.07 0.936,1.22 246 2460 0.6531 0.942 0.726,1.22 59 584
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.6442 0.94 0.724,1.22 59 590 0.6531 0.942 0.726,1.22 59 584
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.1618 0.899 0.775,1.04 195 1950 0.1618 0.899 0.775,1.04 195 1950
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.5649 1.03 0.936,1.13 504 4732 0.5649 1.03 0.936,1.13 504 4732
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.787 1.01 0.915,1.12 420 4080 0.787 1.01 0.915,1.12 420 4080
665 Obstetrical/birth trauma pregnancy complications Female 0.1667 0.948 0.878,1.02 751 6161 0.1667 0.948 0.878,1.02 751 6161
669 Complications of labor and delivery NEC pregnancy complications Female 0.1837 0.947 0.874,1.03 671 5265 0.1837 0.947 0.874,1.03 671 5265
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.3864 0.933 0.798,1.09 172 1720 0.3864 0.933 0.798,1.09 172 1720
674 Other complications of the puerperium NEC pregnancy complications Female 0.004571 0.801 0.688,0.934 181 1810 0.004571 0.801 0.688,0.934 181 1810
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.5333 0.941 0.779,1.14 122 1220 0.5333 0.941 0.779,1.14 122 1220
681 Superficial cellulitis and abscess dermatologic Both 0.0309 1.03 1.0,1.06 5078 31991 0.984 0.999 0.942,1.06 1219 12271
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.04677 1.07 1.0,1.15 862 8581 0.05754 1.07 0.998,1.15 852 8524
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.1148 1.06 0.986,1.14 781 7775 0.1222 1.06 0.984,1.14 778 7725
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.1445 1.04 0.987,1.1 1533 15238 0.1941 1.04 0.982,1.09 1515 15137
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.08913 1.05 0.993,1.1 1649 16359 0.09333 1.04 0.993,1.1 1631 16239
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.4365 1.02 0.966,1.08 1291 12850 0.4898 1.02 0.964,1.08 1276 12760
681.7 Cellulitis and abscess of trunk dermatologic Both 0.877 0.995 0.939,1.06 1238 12342 0.984 0.999 0.942,1.06 1219 12271
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.3304 1.03 0.975,1.08 1660 16466 0.5152 0.938 0.775,1.14 121 1195
686.1 Carbuncle and furuncle dermatologic Both 0.9506 0.997 0.896,1.11 390 3881 0.7762 0.985 0.885,1.1 386 3859
686.2 Impetigo dermatologic Both 0.6855 0.976 0.867,1.1 310 3068 0.6138 0.97 0.862,1.09 308 3059
686.3 Pilonidal cyst dermatologic Both 0.3945 1.09 0.898,1.31 120 1200 0.375 1.09 0.901,1.32 120 1191
686.4 Pyogenic granuloma dermatologic Both 0.5 0.936 0.773,1.13 121 1205 0.5152 0.938 0.775,1.14 121 1195
687 Symptoms affecting skin dermatologic Both 0.9354 1.0 0.973,1.03 6119 25901 0.4932 1.01 0.98,1.04 4911 25417
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.9528 0.999 0.97,1.03 5371 25824 0.8851 0.998 0.969,1.03 5333 25652
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.9333 0.999 0.969,1.03 5264 25870 0.8511 0.997 0.968,1.03 5207 25698
687.3 Changes in skin texture dermatologic Both 0.6397 0.972 0.864,1.09 294 2926 0.8035 0.985 0.875,1.11 292 2905
687.4 Disturbance of skin sensation dermatologic Both 0.5358 1.01 0.979,1.04 4942 25586 0.4932 1.01 0.98,1.04 4911 25417
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.1164 1.02 0.995,1.05 7192 31086 0.1245 1.02 0.994,1.05 7127 30876
690 Erythematosquamous dermatosis dermatologic Both 0.2042 1.02 0.988,1.06 3810 26256 0.2535 1.02 0.986,1.06 3772 26032
690.1 Seborrheic dermatitis dermatologic Both 0.2208 1.02 0.987,1.06 3802 26218 0.2535 1.02 0.986,1.06 3772 26032
691 Congenital anomalies of skin dermatologic Both 0.3767 0.956 0.864,1.06 411 4110 0.4178 0.959 0.867,1.06 410 4091
694 Dyschromia and Vitiligo dermatologic Both 0.228 0.966 0.912,1.02 1286 12819 0.8185 1.03 0.814,1.3 69 682
694.1 Vitiligo dermatologic Both 0.415 0.921 0.755,1.12 94 931 0.4159 0.921 0.755,1.12 94 929
694.2 Other dyschromia dermatologic Both 0.413 0.975 0.918,1.04 1146 11421 0.3776 0.973 0.916,1.03 1140 11366
694.3 Vascular disorders of skin dermatologic Both 0.7943 1.03 0.817,1.3 69 686 0.8185 1.03 0.814,1.3 69 682
695 Erythematous conditions dermatologic Both 0.6237 0.991 0.954,1.03 3180 24642 0.2965 0.952 0.869,1.04 504 5072
695.2 Bullous dermatoses dermatologic Both 0.4169 0.906 0.715,1.15 68 658 0.3981 0.903 0.712,1.14 67 651
695.3 Rosacea dermatologic Both 0.6966 0.989 0.936,1.04 1405 14019 0.6353 0.987 0.934,1.04 1398 13946
695.4 Lupus (localized and systemic) dermatologic Both 0.7943 1.01 0.926,1.11 556 5556 0.9462 0.997 0.909,1.09 529 5279
695.41 Cutaneous lupus erythematosus dermatologic Both 0.8913 1.01 0.868,1.18 196 1955 0.8872 1.01 0.869,1.18 195 1951
695.42 Systemic lupus erythematosus dermatologic Both 0.9594 0.998 0.91,1.09 530 5287 0.9462 0.997 0.909,1.09 529 5279
695.7 Prurigo and Lichen dermatologic Both 0.3565 1.05 0.948,1.16 429 4275 0.3681 1.05 0.947,1.16 427 4252
695.8 Other specified erythematous conditions dermatologic Both 0.9311 0.996 0.917,1.08 613 6111 0.9727 0.999 0.919,1.09 608 6089
695.9 Unspecified erythematous condition dermatologic Both 0.3428 0.957 0.874,1.05 513 5102 0.2965 0.952 0.869,1.04 504 5072
696 Psoriasis and related disorders dermatologic Both 0.3034 0.968 0.909,1.03 1080 10781 0.4227 0.944 0.821,1.09 223 2233
696.3 Pityriasis dermatologic Both 0.01905 0.735 0.568,0.951 64 640 0.02042 0.737 0.57,0.954 64 638
696.4 Psoriasis dermatologic Both 0.8035 0.992 0.93,1.06 1014 10115 0.4227 0.944 0.821,1.09 223 2233
696.41 Psoriasis vulgaris dermatologic Both 0.877 1.01 0.94,1.08 918 9161 0.9931 1.0 0.934,1.07 910 9090
696.42 Psoriatic arthropathy dermatologic Both 0.3882 0.94 0.818,1.08 225 2250 0.4227 0.944 0.821,1.09 223 2233
697 Sarcoidosis dermatologic Both 0.2286 1.08 0.952,1.23 265 2650 0.2109 1.08 0.955,1.23 261 2632
698 Pruritus and related conditions dermatologic Both 0.955 1.0 0.952,1.05 1686 16680 0.9572 1.0 0.952,1.05 1674 16624
700 Corns and callosities dermatologic Both 0.4375 1.03 0.956,1.11 764 7615 0.414 1.03 0.958,1.11 761 7558
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.4753 0.99 0.962,1.02 5838 31889 0.514 0.963 0.861,1.08 324 3237
701.1 Keratoderma, acquired dermatologic Both 0.317 0.949 0.856,1.05 389 3845 0.3069 0.947 0.854,1.05 385 3817
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.865 1.0 0.955,1.06 1705 16953 0.875 1.0 0.955,1.06 1690 16877
701.3 Circumscribed scleroderma dermatologic Both 0.04467 0.904 0.819,0.998 434 4334 0.04365 0.903 0.818,0.997 430 4327
701.4 Keloid scar dermatologic Both 0.8091 1.01 0.919,1.11 454 4503 0.811 1.01 0.919,1.11 450 4487
701.5 Abnormal granulation tissue dermatologic Both 0.5458 0.966 0.864,1.08 328 3260 0.514 0.963 0.861,1.08 324 3237
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.257 1.02 0.987,1.05 5351 24908 0.07413 1.27 0.977,1.65 62 622
702.1 Actinic keratosis dermatologic Both 0.7586 1.01 0.969,1.04 3236 22206 0.8395 1.0 0.967,1.04 3204 22054
702.2 Seborrheic keratosis dermatologic Both 0.08128 1.03 0.996,1.07 4151 26248 0.06761 1.03 0.998,1.07 4118 26077
702.4 Degenerative skin disorders dermatologic Both 0.08318 1.26 0.97,1.64 63 624 0.07413 1.27 0.977,1.65 62 622
703 Diseases of nail, NOS dermatologic Both 0.3597 1.03 0.966,1.1 1033 10222 0.1148 0.934 0.857,1.02 577 5739
703.1 Ingrowing nail dermatologic Both 0.1102 0.933 0.857,1.02 580 5773 0.1148 0.934 0.857,1.02 577 5739
704 Diseases of hair and hair follicles dermatologic Both 0.6546 0.99 0.949,1.03 2321 22718 0.3954 0.975 0.921,1.03 1269 12698
704.1 Alopecia dermatologic Both 0.6281 1.02 0.953,1.08 1074 10601 0.09333 0.809 0.631,1.04 58 578
704.11 Alopecia Areata dermatologic Both 0.0912 0.808 0.63,1.04 58 580 0.09333 0.809 0.631,1.04 58 578
704.2 Hirsutism dermatologic Both 0.9268 0.994 0.867,1.14 227 2263 0.9247 0.994 0.867,1.14 227 2262
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.4498 0.978 0.924,1.04 1286 12791 0.3954 0.975 0.921,1.03 1269 12698
705 Disorders of sweat glands dermatologic Both 0.0537 1.1 0.998,1.22 439 4376 0.5035 1.02 0.954,1.1 840 8367
705.1 Dyshidrosis dermatologic Both 0.2606 1.12 0.919,1.37 114 1131 0.2183 1.13 0.929,1.38 113 1123
705.3 Hidradenitis dermatologic Both 0.1256 1.13 0.966,1.32 183 1815 0.1271 1.13 0.966,1.32 183 1812
705.8 Hyperhidrosis dermatologic Both 0.5035 1.02 0.954,1.1 846 8429 0.5035 1.02 0.954,1.1 840 8367
706 Diseases of sebaceous glands dermatologic Both 0.1202 0.975 0.945,1.01 4454 32859 0.1884 0.959 0.902,1.02 1116 11041
706.1 Acne dermatologic Both 0.07762 0.959 0.915,1.0 1931 17499 0.0631 0.956 0.912,1.0 1917 17403
706.2 Sebaceous cyst dermatologic Both 0.826 0.995 0.952,1.04 2150 21106 0.7962 0.994 0.951,1.04 2130 20971
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.2153 0.962 0.904,1.02 1124 11122 0.1884 0.959 0.902,1.02 1116 11041
707 Chronic ulcer of skin dermatologic Both 0.4732 1.02 0.973,1.06 2193 21811 0.4335 1.02 0.967,1.08 1329 13285
707.1 Decubitus ulcer dermatologic Both 0.778 1.01 0.931,1.1 600 5984 0.7464 1.01 0.932,1.1 595 5922
707.2 Chronic ulcer of leg or foot dermatologic Both 0.3475 1.04 0.961,1.12 721 7166 0.3177 1.04 0.963,1.12 715 7100
707.3 Chronic ulcer of unspecified site dermatologic Both 0.3819 1.03 0.969,1.09 1339 13370 0.4335 1.02 0.967,1.08 1329 13285
709 Diffuse diseases of connective tissue dermatologic Both 0.1652 1.05 0.982,1.11 1086 10825 0.8511 1.01 0.929,1.09 657 6540
709.2 Sicca syndrome dermatologic Both 0.9886 1.0 0.898,1.12 365 3650 0.9772 0.998 0.895,1.11 363 3647
709.3 Systemic sclerosis dermatologic Both 0.492 0.948 0.815,1.1 184 1840 0.4875 0.948 0.814,1.1 183 1837
709.5 Dermatomyositis dermatologic Both 0.4055 1.11 0.865,1.43 70 700 0.4111 1.11 0.864,1.43 70 696
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.8933 0.984 0.774,1.25 78 780 0.8974 0.984 0.775,1.25 78 779
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.8318 1.01 0.93,1.09 659 6563 0.8511 1.01 0.929,1.09 657 6540
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.5768 1.01 0.979,1.04 5120 27320 0.09333 1.27 0.961,1.67 64 624
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.1 1.26 0.957,1.66 64 626 0.09333 1.27 0.961,1.67 64 624
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.7261 0.988 0.926,1.06 954 9524 0.7194 1.01 0.945,1.09 859 8575
710.1 Osteomyelitis musculoskeletal Both 0.9376 1.0 0.937,1.07 914 9127 0.7194 1.01 0.945,1.09 859 8575
710.11 Acute osteomyelitis musculoskeletal Both 0.5875 0.973 0.883,1.07 425 4234 0.6427 0.977 0.886,1.08 423 4194
710.12 Chronic osteomyelitis musculoskeletal Both 0.9484 1.0 0.904,1.11 378 3758 0.9931 1.0 0.9,1.11 376 3718
710.19 Unspecified osteomyelitis musculoskeletal Both 0.7816 1.01 0.942,1.08 867 8656 0.7194 1.01 0.945,1.09 859 8575
711 Arthropathy associated with infections musculoskeletal Both 0.003981 1.19 1.06,1.33 314 3124 0.06918 1.14 0.99,1.31 221 2181
711.1 Pyogenic arthritis musculoskeletal Both 0.06166 1.14 0.994,1.31 223 2206 0.06918 1.14 0.99,1.31 221 2181
712 Infective connective tissue disorders musculoskeletal Both 0.6531 0.961 0.81,1.14 136 1360 0.7211 0.969 0.816,1.15 135 1349
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.03236 1.17 1.01,1.34 222 2214 0.02344 1.25 1.03,1.52 117 1173
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.0389 1.23 1.01,1.49 118 1180 0.02344 1.25 1.03,1.52 117 1173
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.3069 0.974 0.925,1.02 1649 14662 0.514 0.981 0.927,1.04 1336 12271
714.1 Rheumatoid arthritis musculoskeletal Both 0.4699 0.979 0.925,1.04 1342 12332 0.514 0.981 0.927,1.04 1336 12271
715 Other inflammatory spondylopathies musculoskeletal Both 0.1714 1.05 0.98,1.12 979 9761 0.7129 0.972 0.835,1.13 177 1744
715.1 Sacroiliitis NEC musculoskeletal Both 0.6966 1.03 0.892,1.19 212 2120 0.7031 1.03 0.891,1.19 212 2108
715.2 Ankylosing spondylitis musculoskeletal Both 0.6966 0.97 0.833,1.13 177 1760 0.7129 0.972 0.835,1.13 177 1744
716 Other arthropathies musculoskeletal Both 0.04898 0.977 0.954,1.0 10893 26011 0.08913 0.98 0.957,1.0 10763 25807
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.695 0.968 0.823,1.14 155 1540 0.7328 0.972 0.826,1.14 153 1533
716.2 Unspecified monoarthritis musculoskeletal Both 0.6442 0.957 0.795,1.15 116 1156 0.7656 0.972 0.806,1.17 114 1149
716.9 Arthropathy NOS musculoskeletal Both 0.05888 0.978 0.955,1.0 10831 26002 0.08913 0.98 0.957,1.0 10763 25807
717 Polymyalgia Rheumatica musculoskeletal Both 0.2188 1.1 0.947,1.27 210 2061 0.1718 1.11 0.956,1.28 206 2044
720 Spinal stenosis musculoskeletal Both 0.869 1.0 0.967,1.04 3298 24117 0.413 0.982 0.942,1.03 2399 20291
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.3162 0.979 0.938,1.02 2415 20454 0.413 0.982 0.942,1.03 2399 20291
721 Spondylosis and allied disorders musculoskeletal Both 0.6412 1.01 0.976,1.04 4494 27007 0.863 1.01 0.877,1.17 209 2082
721.1 Spondylosis without myelopathy musculoskeletal Both 0.6699 1.01 0.975,1.04 4206 26584 0.5598 1.01 0.977,1.04 4178 26387
721.2 Spondylosis with myelopathy musculoskeletal Both 0.861 1.01 0.933,1.09 740 7398 0.8054 1.01 0.935,1.09 738 7343
721.8 Other allied disorders of spine musculoskeletal Both 0.9908 0.999 0.867,1.15 212 2099 0.863 1.01 0.877,1.17 209 2082
722 Intervertebral disc disorders musculoskeletal Both 0.869 1.0 0.973,1.03 5242 28702 0.7998 1.01 0.956,1.06 1559 15560
722.1 Displacement of intervertebral disc musculoskeletal Both 0.8279 0.996 0.959,1.03 3038 26827 0.875 0.997 0.96,1.04 3017 26625
722.3 Schmorl's nodes musculoskeletal Both 0.7413 1.03 0.857,1.24 115 1140 0.7096 1.04 0.86,1.25 115 1128
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.9705 0.999 0.964,1.04 3338 26140 0.9727 1.0 0.965,1.04 3321 25944
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.7464 0.984 0.894,1.08 464 4634 0.7889 0.987 0.896,1.09 462 4589
722.8 Postlaminectomy syndrome musculoskeletal Both 0.04898 1.12 1.0,1.26 336 3360 0.04786 1.13 1.0,1.26 334 3334
722.9 Other and unspecified disc disorder musculoskeletal Both 0.8551 1.0 0.954,1.06 1569 15676 0.7998 1.01 0.956,1.06 1559 15560
723 Other disorders of cervical region musculoskeletal Both 0.5861 0.979 0.909,1.06 761 7610 0.1191 0.89 0.769,1.03 185 1850
723.1 Torticollis musculoskeletal Both 0.1324 0.894 0.773,1.03 187 1870 0.1191 0.89 0.769,1.03 185 1850
724 Other and unspecified disorders of back musculoskeletal Both 0.7178 0.993 0.958,1.03 3338 26730 0.7362 1.01 0.953,1.07 1240 12326
724.1 Disorders of sacrum musculoskeletal Both 0.3741 0.978 0.932,1.03 1804 17663 0.4246 0.98 0.934,1.03 1795 17581
724.2 Disorders of coccyx musculoskeletal Both 0.1714 0.924 0.825,1.03 331 3290 0.173 0.924 0.825,1.04 329 3271
724.8 Other symptoms referable to back musculoskeletal Both 0.5521 1.02 0.949,1.1 753 7499 0.4989 1.03 0.952,1.11 749 7452
724.9 Other unspecified back disorders musculoskeletal Both 0.7278 1.01 0.953,1.07 1246 12418 0.7362 1.01 0.953,1.07 1240 12326
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.6339 1.01 0.981,1.03 7682 25455 0.07943 1.06 0.992,1.14 885 8799
726.1 Enthesopathy musculoskeletal Both 0.7194 1.01 0.977,1.03 5795 25454 0.6383 1.01 0.978,1.04 5761 25263
726.2 Synoviopathy musculoskeletal Both 0.6266 1.02 0.946,1.1 774 7723 0.6124 1.02 0.947,1.1 770 7665
726.3 Bursitis musculoskeletal Both 0.3908 1.02 0.969,1.08 1339 13090 0.3837 1.03 0.969,1.09 1327 12999
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.105 1.06 0.988,1.14 889 8846 0.07943 1.06 0.992,1.14 885 8799
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.7295 0.995 0.967,1.02 5811 25457 0.2317 0.891 0.737,1.08 115 1106
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.5728 0.988 0.946,1.03 2342 20541 0.5284 0.986 0.945,1.03 2332 20420
727.2 Bursitis disorders musculoskeletal Both 0.342 1.06 0.944,1.18 341 3381 0.3177 1.06 0.947,1.18 339 3355
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.06026 0.942 0.886,1.0 1109 11034 0.05888 0.942 0.886,1.0 1104 10976
727.5 Rupture of synovium musculoskeletal Both 0.5105 0.965 0.867,1.07 376 3718 0.492 0.963 0.865,1.07 374 3696
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.3273 1.02 0.977,1.07 1927 18092 0.4246 1.02 0.972,1.07 1908 17941
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.5284 0.971 0.887,1.06 520 5187 0.547 0.972 0.888,1.07 519 5145
727.8 Plica syndrome musculoskeletal Both 0.2065 0.885 0.733,1.07 115 1117 0.2317 0.891 0.737,1.08 115 1106
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.8091 0.996 0.96,1.03 3433 24951 0.8511 1.01 0.9,1.14 307 3060
728.1 Muscular calcification and ossification musculoskeletal Both 0.4898 0.92 0.725,1.17 69 682 0.4276 0.908 0.715,1.15 68 679
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.7096 0.975 0.854,1.11 230 2298 0.7345 0.977 0.856,1.12 230 2286
728.7 Fasciitis musculoskeletal Both 0.877 0.996 0.952,1.04 2056 19042 0.8511 1.01 0.9,1.14 307 3060
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.877 1.01 0.899,1.13 310 3095 0.8511 1.01 0.9,1.14 307 3060
729 Other disorders of soft tissues musculoskeletal Both 0.2944 0.979 0.94,1.02 2618 22751 0.975 1.0 0.758,1.33 51 520
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.6607 0.946 0.736,1.21 63 630 0.6081 0.936 0.728,1.2 62 629
729.3 Panniculitis musculoskeletal Both 0.3436 1.11 0.898,1.36 100 1000 0.3459 1.11 0.897,1.37 99 997
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.8035 1.04 0.787,1.36 53 530 0.975 1.0 0.758,1.33 51 520
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.3908 0.928 0.783,1.1 145 1441 0.4375 0.934 0.788,1.11 143 1432
732 Osteochondropathies musculoskeletal Both 0.2042 0.925 0.821,1.04 289 2882 0.4395 0.909 0.713,1.16 71 705
732.1 Juvenile osteochondrosis musculoskeletal Both 0.07244 0.863 0.735,1.01 157 1570 0.06918 0.861 0.733,1.01 156 1554
732.7 Osteochondritis dissecans musculoskeletal Both 0.4178 0.905 0.709,1.15 71 710 0.4395 0.909 0.713,1.16 71 705
733 Other disorders of bone and cartilage musculoskeletal Both 0.8128 0.996 0.96,1.03 3481 21966 0.08913 1.21 0.971,1.51 80 796
733.2 Cyst of bone musculoskeletal Both 0.06607 0.865 0.741,1.01 162 1613 0.0631 0.863 0.739,1.01 161 1603
733.4 Aseptic necrosis of bone musculoskeletal Both 0.02042 1.13 1.02,1.25 405 4042 0.02138 1.13 1.02,1.25 402 4008
733.6 Costochondritis musculoskeletal Both 0.4345 0.951 0.84,1.08 275 2742 0.3639 0.944 0.833,1.07 273 2734
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.1928 1.05 0.974,1.14 701 7003 0.1622 1.06 0.978,1.14 698 6939
733.9 Chondromalacia musculoskeletal Both 0.08913 1.21 0.971,1.52 80 800 0.08913 1.21 0.971,1.51 80 796
735 Acquired foot deformities musculoskeletal Both 0.1644 1.03 0.988,1.07 2431 23304 0.3243 1.03 0.969,1.1 1036 10256
735.1 Flat foot musculoskeletal Both 0.9141 1.01 0.911,1.11 437 4355 0.9268 1.0 0.91,1.11 435 4325
735.2 Acquired toe deformities musculoskeletal Both 0.9661 1.0 0.934,1.07 869 8616 0.5821 0.968 0.861,1.09 299 2968
735.21 Hammer toe (acquired) musculoskeletal Both 0.335 1.05 0.954,1.15 509 5041 0.2793 1.05 0.959,1.15 506 5014
735.23 Hallux rigidus musculoskeletal Both 0.5875 0.968 0.861,1.09 299 2975 0.5821 0.968 0.861,1.09 299 2968
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.3475 1.03 0.967,1.1 1039 10308 0.3243 1.03 0.969,1.1 1036 10256
736 Other acquired deformities of limbs musculoskeletal Both 0.263 1.03 0.98,1.08 1997 19771 0.8375 0.987 0.869,1.12 254 2544
736.1 Acquired deformities of forearm musculoskeletal Both 0.01175 1.34 1.07,1.68 90 892 0.01122 1.34 1.07,1.68 90 883
736.2 Acquired deformities of finger musculoskeletal Both 0.4102 0.937 0.803,1.09 169 1684 0.3027 0.922 0.789,1.08 166 1670
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.7295 1.02 0.898,1.17 239 2382 0.7063 1.03 0.899,1.17 237 2369
736.5 Acquired deformities of knee musculoskeletal Both 0.8872 1.01 0.871,1.17 184 1834 0.9099 1.01 0.869,1.17 183 1818
736.6 Unequal leg length (acquired) musculoskeletal Both 0.8472 0.988 0.87,1.12 256 2555 0.8375 0.987 0.869,1.12 254 2544
737 Curvature of spine musculoskeletal Both 0.8035 1.01 0.951,1.07 1268 12573 0.5284 0.979 0.917,1.05 983 9732
737.1 Kyphosis (acquired) musculoskeletal Both 0.6516 1.02 0.921,1.14 383 3819 0.7161 1.02 0.917,1.13 380 3792
737.2 Lordosis (acquired) musculoskeletal Both 0.4764 1.1 0.848,1.42 65 650 0.5272 1.09 0.839,1.41 64 647
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.4775 0.977 0.915,1.04 987 9782 0.5284 0.979 0.917,1.05 983 9732
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.778 1.01 0.961,1.05 1968 19555 0.5164 1.02 0.954,1.1 861 8557
738.4 Acquired spondylolisthesis musculoskeletal Both 0.4842 1.03 0.956,1.1 863 8617 0.5164 1.02 0.954,1.1 861 8557
739 Contracture of joint musculoskeletal Both 0.6902 0.982 0.897,1.07 522 5203 0.7063 0.983 0.898,1.08 520 5165
740 Osteoarthrosis musculoskeletal Both 0.0955 0.981 0.96,1.0 13133 25195 0.1361 0.983 0.961,1.01 12572 24881
740.1 Osteoarthritis; localized musculoskeletal Both 0.5754 0.991 0.961,1.02 5329 22764 0.317 0.955 0.873,1.05 510 5095
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.5534 0.99 0.958,1.02 4543 21500 0.5834 0.991 0.959,1.02 4516 21324
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.2698 0.951 0.869,1.04 514 5125 0.317 0.955 0.873,1.05 510 5095
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.9162 0.997 0.94,1.06 1266 9917 0.9977 1.0 0.943,1.06 1255 9860
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.6607 1.03 0.912,1.16 303 2974 0.6295 1.03 0.915,1.16 302 2955
740.9 Osteoarthrosis NOS musculoskeletal Both 0.09333 0.981 0.959,1.0 12648 25075 0.1361 0.983 0.961,1.01 12572 24881
741 Symptoms and disorders of the joints musculoskeletal Both 0.9247 0.999 0.973,1.03 6764 29838 0.278 0.859 0.653,1.13 53 522
741.1 Ankylosis of joint musculoskeletal Both 0.02692 0.857 0.748,0.983 209 2088 0.02399 0.854 0.744,0.979 207 2073
741.2 Stiffness of joint musculoskeletal Both 0.8356 0.993 0.93,1.06 995 9908 0.8395 0.993 0.93,1.06 990 9851
741.3 Difficulty in walking musculoskeletal Both 0.6531 1.01 0.964,1.06 1854 17778 0.6194 1.01 0.965,1.06 1844 17636
741.4 Joint effusions musculoskeletal Both 0.9376 0.998 0.952,1.05 1930 19185 0.9528 1.0 0.955,1.05 1922 19052
741.5 Hemarthrosis musculoskeletal Both 0.1945 0.85 0.666,1.09 64 640 0.2004 0.852 0.667,1.09 64 635
741.6 Villonodular synovitis musculoskeletal Both 0.278 0.859 0.653,1.13 53 522 0.278 0.859 0.653,1.13 53 522
742 Derangement of joint, non-traumatic musculoskeletal Both 0.8147 1.0 0.969,1.04 3462 27650 0.9376 1.0 0.965,1.04 3194 26696
742.1 Loose body in joint musculoskeletal Both 0.257 0.904 0.759,1.08 131 1295 0.2851 0.909 0.763,1.08 130 1281
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.9099 0.992 0.87,1.13 243 2414 0.9506 0.996 0.873,1.14 240 2397
742.8 Articular cartilage disorder musculoskeletal Both 0.6998 0.972 0.843,1.12 191 1896 0.7798 0.98 0.85,1.13 190 1882
742.9 Other derangement of joint musculoskeletal Both 0.9016 1.0 0.966,1.04 3212 26883 0.9376 1.0 0.965,1.04 3194 26696
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.631 0.994 0.968,1.02 7571 30458 0.5047 0.99 0.962,1.02 5767 29236
743.1 Osteoporosis musculoskeletal Both 0.4853 0.985 0.946,1.03 2982 15823 0.3524 1.07 0.93,1.23 231 2277
743.11 Osteoporosis NOS musculoskeletal Both 0.7031 0.992 0.952,1.03 2931 15630 0.6998 0.992 0.952,1.03 2924 15545
743.12 Senile osteoporosis musculoskeletal Both 0.3899 0.959 0.871,1.06 481 4333 0.4046 0.96 0.873,1.06 481 4324
743.13 Other specified osteoporosis musculoskeletal Both 0.3631 1.07 0.928,1.23 231 2290 0.3524 1.07 0.93,1.23 231 2277
743.2 Pathologic fracture musculoskeletal Both 0.2228 0.958 0.893,1.03 872 8504 0.4875 1.07 0.882,1.3 114 1139
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.3581 1.05 0.945,1.17 385 3799 0.3614 1.05 0.944,1.17 384 3765
743.22 Pathologic fracture of femur musculoskeletal Both 0.4227 1.08 0.892,1.31 116 1143 0.4875 1.07 0.882,1.3 114 1139
743.4 Stress fracture musculoskeletal Both 0.929 0.994 0.88,1.12 291 2882 0.912 0.993 0.879,1.12 288 2870
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.4853 0.99 0.961,1.02 5795 29464 0.5047 0.99 0.962,1.02 5767 29236
745 Pain in joint musculoskeletal Both 0.7278 1.0 0.983,1.02 15755 22596 0.6486 1.0 0.984,1.03 15664 22411
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.8414 0.995 0.948,1.04 1811 18049 0.4467 0.961 0.868,1.06 397 3984
747.1 Cardiac congenital anomalies congenital anomalies Both 0.8433 0.995 0.942,1.05 1446 14417 0.7261 1.02 0.912,1.14 339 3357
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.7311 0.984 0.9,1.08 519 5181 0.7413 0.985 0.9,1.08 515 5139
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.8072 0.99 0.913,1.07 632 6299 0.863 0.993 0.916,1.08 631 6220
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.5702 1.03 0.923,1.16 342 3387 0.7261 1.02 0.912,1.14 339 3357
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.5212 0.967 0.874,1.07 402 4014 0.4467 0.961 0.868,1.06 397 3984
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.1442 1.18 0.946,1.47 93 930 0.1479 1.18 0.944,1.46 93 928
749 Congenital anomalies of face and neck congenital anomalies Both 0.4295 0.961 0.872,1.06 455 4540 0.8395 0.978 0.789,1.21 89 889
749.1 Cleft palate congenital anomalies Both 0.6531 1.05 0.84,1.32 81 791 0.6266 1.06 0.844,1.33 81 784
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.9247 0.99 0.799,1.23 90 897 0.8395 0.978 0.789,1.21 89 889
750 Digestive congenital anomalies congenital anomalies Both 0.2307 0.955 0.885,1.03 739 7382 0.3622 0.93 0.797,1.09 180 1777
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.8954 1.01 0.896,1.13 307 3069 0.4498 0.906 0.701,1.17 56 565
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.1932 1.15 0.93,1.43 96 944 0.1845 1.16 0.932,1.44 95 935
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.177 0.856 0.682,1.07 77 767 0.1919 0.86 0.686,1.08 77 762
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.06607 1.2 0.988,1.45 121 1210 0.0631 1.2 0.99,1.45 121 1196
750.15 Congenital anomalies of stomach congenital anomalies Both 0.4207 0.901 0.698,1.16 57 567 0.4498 0.906 0.701,1.17 56 565
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.07943 0.916 0.83,1.01 438 4363 0.3622 0.93 0.797,1.09 180 1777
750.21 Congenital anomalies of intestine congenital anomalies Both 0.2477 0.928 0.817,1.05 262 2613 0.2786 0.932 0.82,1.06 256 2604
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.3475 0.928 0.795,1.08 180 1790 0.3622 0.93 0.797,1.09 180 1777
751 Genitourinary congenital anomalies congenital anomalies Both 0.7063 1.01 0.96,1.06 1682 16764 0.5236 1.05 0.899,1.23 157 1554
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.5821 1.03 0.935,1.13 491 4897 0.2128 1.12 0.935,1.35 123 1279
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.7568 1.02 0.906,1.15 328 3280 0.7568 1.02 0.906,1.15 328 3280
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.3396 1.09 0.913,1.3 132 1301 0.2128 1.12 0.935,1.35 123 1279
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.695 1.01 0.952,1.08 1139 11355 0.1125 0.9 0.791,1.02 247 2486
751.21 Cystic kidney disease congenital anomalies Both 0.4977 1.03 0.954,1.1 799 7929 0.5082 1.02 0.953,1.1 793 7874
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.2051 0.92 0.809,1.05 251 2506 0.1125 0.9 0.791,1.02 247 2486
751.3 Obstructive genitourinary defect congenital anomalies Both 0.5534 1.05 0.896,1.23 157 1560 0.5236 1.05 0.899,1.23 157 1554
752 Nervous system congenital anomalies congenital anomalies Both 0.7228 1.01 0.946,1.08 908 9073 0.1377 1.12 0.965,1.3 199 2002
752.1 Neural tube defects congenital anomalies Both 0.6577 1.02 0.943,1.1 728 7277 0.5176 1.06 0.887,1.27 143 1433
752.11 Spina bifida congenital anomalies Both 0.5188 1.06 0.887,1.27 144 1440 0.5176 1.06 0.887,1.27 143 1433
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.1227 1.12 0.969,1.3 201 2010 0.1377 1.12 0.965,1.3 199 2002
753 Congenital anomalies of the eye congenital anomalies Both 0.1114 1.15 0.969,1.36 146 1451 0.171 1.13 0.95,1.33 143 1437
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.4732 1.02 0.96,1.09 1006 10049 0.6902 1.02 0.928,1.12 470 4638
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.3565 0.914 0.756,1.11 116 1155 0.3784 0.918 0.759,1.11 116 1144
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.7278 1.02 0.926,1.12 470 4675 0.6902 1.02 0.928,1.12 470 4638
755 Congenital anomalies of limbs congenital anomalies Both 0.7063 0.984 0.907,1.07 625 6237 0.798 0.978 0.828,1.16 152 1515
755.1 Congenital deformities of feet congenital anomalies Both 0.7096 0.978 0.871,1.1 315 3138 0.6776 0.976 0.868,1.1 313 3128
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.9016 0.984 0.757,1.28 58 567 0.9099 0.985 0.758,1.28 58 566
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.6637 0.972 0.855,1.11 258 2580 0.798 0.978 0.828,1.16 152 1515
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.7798 0.977 0.827,1.15 152 1520 0.798 0.978 0.828,1.16 152 1515
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.9638 0.999 0.936,1.07 1021 10203 0.7161 0.986 0.915,1.06 739 7368
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.05623 0.764 0.579,1.01 55 527 0.06026 0.767 0.581,1.01 55 525
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.1052 1.27 0.951,1.69 56 524 0.0955 1.28 0.957,1.71 56 521
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.9616 0.997 0.874,1.14 246 2459 0.9705 0.998 0.875,1.14 245 2445
756.5 Congenital osteodystrophies congenital anomalies Both 0.7345 0.987 0.916,1.06 743 7419 0.7161 0.986 0.915,1.06 739 7368
757 Congenital anomalies of the integument congenital anomalies Both 0.5521 0.963 0.851,1.09 283 2820 0.5662 0.964 0.852,1.09 281 2812
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.06166 1.19 0.992,1.43 134 1334 0.4853 1.08 0.868,1.35 91 906
758.1 Chromosomal anomalies congenital anomalies Both 0.4898 1.08 0.867,1.35 91 910 0.4853 1.08 0.868,1.35 91 906
759 Other and unspecified congenital anomalies congenital anomalies Both 0.5395 1.03 0.938,1.13 498 4964 0.6295 1.07 0.811,1.41 57 566
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.6486 1.07 0.809,1.41 57 567 0.6295 1.07 0.811,1.41 57 566
760 Back pain symptoms Both 0.984 1.0 0.979,1.02 12687 25663 0.9727 1.0 0.979,1.02 12603 25471
761 Cervicalgia symptoms Both 0.03802 1.03 1.0,1.06 5134 32829 0.03467 1.03 1.0,1.06 5105 32589
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.3133 0.981 0.944,1.02 2927 27356 0.3381 0.982 0.945,1.02 2909 27160
764 Sciatica symptoms Both 0.8492 1.0 0.964,1.05 2623 25291 0.8054 1.01 0.965,1.05 2606 25131
765 Cervical radiculitis symptoms Both 0.07413 1.05 0.995,1.11 1401 13966 0.08913 1.05 0.993,1.11 1390 13870
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.3228 1.02 0.984,1.05 4004 31031 0.3105 1.02 0.984,1.05 3979 30804
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.2075 0.865 0.691,1.08 85 835 0.2198 0.869 0.694,1.09 85 833
769 Nonallopathic lesions NEC symptoms Both 0.8933 0.995 0.929,1.07 923 9183 0.8954 0.995 0.929,1.07 920 9149
770 Myalgia and myositis unspecified symptoms Both 0.6516 0.993 0.961,1.03 4324 27592 0.6281 0.992 0.96,1.02 4307 27431
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.798 0.996 0.962,1.03 3638 29710 0.3639 1.03 0.961,1.11 787 7815
771.1 Swelling of limb symptoms Both 0.4539 0.988 0.957,1.02 4511 29862 0.5093 0.989 0.959,1.02 4466 29655
771.2 Cramp of limb symptoms Both 0.3846 1.03 0.96,1.11 791 7856 0.3639 1.03 0.961,1.11 787 7815
772 Symptoms of the muscles symptoms Both 0.1556 0.963 0.914,1.01 1549 15345 0.3776 0.953 0.857,1.06 372 3715
772.1 Muscular wasting and disuse atrophy symptoms Both 0.4102 1.05 0.936,1.18 320 3187 0.3508 1.06 0.942,1.18 318 3161
772.2 Spasm of muscle symptoms Both 0.5675 1.01 0.966,1.07 1780 17782 0.4436 1.02 0.971,1.07 1773 17679
772.3 Muscle weakness symptoms Both 0.4395 1.02 0.974,1.06 2339 22770 0.4102 1.02 0.975,1.06 2330 22603
772.4 Rhabdomyolysis symptoms Both 0.5598 1.06 0.877,1.27 117 1170 0.7194 1.04 0.858,1.25 114 1156
772.6 Facial weakness symptoms Both 0.5188 0.966 0.869,1.07 377 3746 0.3776 0.953 0.857,1.06 372 3715
773 Pain in limb symptoms Both 0.9441 0.999 0.977,1.02 11393 26958 0.9162 0.999 0.977,1.02 11314 26761
780 Hypothermia/Chills symptoms Both 0.542 0.965 0.86,1.08 307 3069 0.5272 0.964 0.859,1.08 305 3039
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.7328 0.992 0.944,1.04 1767 17206 0.8453 1.02 0.825,1.27 90 884
781.1 Loss of height symptoms Both 0.8872 1.02 0.821,1.26 91 890 0.8453 1.02 0.825,1.27 90 884
782.3 Edema symptoms Both 0.9977 1.0 0.969,1.03 4591 30849 0.9484 1.0 0.97,1.03 4554 30634
782.6 Pallor and flushing symptoms Both 0.6266 1.02 0.942,1.1 679 6769 0.7311 1.01 0.937,1.1 674 6751
783 Fever of unknown origin symptoms Both 0.1694 1.02 0.991,1.05 4616 33703 0.08318 1.12 0.985,1.28 243 2450
783.1 Postprocedural fever symptoms Both 0.05129 1.14 0.999,1.3 248 2473 0.08318 1.12 0.985,1.28 243 2450
785 Abdominal pain symptoms Both 0.6124 1.01 0.984,1.03 13257 25098 0.7278 1.0 0.983,1.03 13157 24922
788 Syncope and collapse symptoms Both 0.9141 1.0 0.965,1.04 3017 29114 0.8954 1.0 0.966,1.04 3000 28913
789 Nausea and vomiting symptoms Both 0.9141 1.0 0.977,1.03 8497 29838 0.2723 0.956 0.881,1.04 631 6305
789.1 Persistent vomiting symptoms Both 0.3006 0.958 0.884,1.04 634 6330 0.2723 0.956 0.881,1.04 631 6305
790 Nonspecific findings on examination of blood symptoms Both 0.354 1.02 0.974,1.08 1740 17356 0.302 0.908 0.757,1.09 123 1220
790.1 Elevated sedimentation rate symptoms Both 0.9016 0.99 0.84,1.17 158 1580 0.9016 0.99 0.839,1.17 157 1575
790.6 Other abnormal blood chemistry symptoms Both 0.9247 0.999 0.969,1.03 4849 31554 0.8892 0.998 0.968,1.03 4812 31334
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.6887 0.971 0.84,1.12 204 2026 0.7447 0.976 0.844,1.13 203 2017
790.9 Abnormal arterial blood gases symptoms Both 0.2904 0.906 0.755,1.09 123 1230 0.302 0.908 0.757,1.09 123 1220
791 Gangrene symptoms Both 0.7638 0.979 0.85,1.13 212 2104 0.9247 0.993 0.861,1.15 210 2087
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.5445 0.986 0.941,1.03 2171 11972 0.1603 0.95 0.883,1.02 841 7806
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.1603 0.95 0.883,1.02 841 7806 0.1603 0.95 0.883,1.02 841 7806
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.2673 0.953 0.876,1.04 588 5848 0.859 1.0 0.955,1.06 1643 16497
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.9226 1.0 0.953,1.05 1661 16601 0.859 1.0 0.955,1.06 1643 16497
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.5082 1.03 0.937,1.14 433 4330 0.4436 1.04 0.942,1.15 429 4295
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.3357 0.975 0.926,1.03 1632 15619 0.04786 0.856 0.734,0.999 167 1658
795.8 Abnormal tumor markers symptoms Both 0.547 0.985 0.937,1.03 1698 13664 0.04786 0.856 0.734,0.999 167 1658
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.05012 0.858 0.735,1.0 167 1662 0.04786 0.856 0.734,0.999 167 1658
796 Elevated prostate specific antigen [PSA] symptoms Male 0.6339 0.987 0.937,1.04 1700 8294 0.8318 0.994 0.943,1.05 1651 8294
797 Shock symptoms Both 0.3266 1.05 0.952,1.16 445 4446 0.2218 1.1 0.943,1.29 180 1799
797.1 Cardiogenic shock symptoms Both 0.2399 1.1 0.939,1.28 183 1822 0.2218 1.1 0.943,1.29 180 1799
798 Malaise and fatigue symptoms Both 0.6577 1.01 0.982,1.03 8867 29476 0.1268 1.05 0.987,1.11 1340 13317
798.1 Chronic fatigue syndrome symptoms Both 0.14 1.04 0.986,1.1 1349 13380 0.1268 1.05 0.987,1.11 1340 13317
799 Debility unspecified symptoms Both 1.0 1.0 0.951,1.05 1672 16007 0.9333 1.0 0.953,1.05 1665 15887
800 Fracture of lower limb injuries & poisonings Both 0.1114 0.962 0.918,1.01 1879 18684 0.2143 0.929 0.828,1.04 292 2875
800.1 Fracture of neck of femur injuries & poisonings Both 0.4436 0.961 0.867,1.06 409 4028 0.4875 0.964 0.869,1.07 404 3999
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.8185 0.99 0.905,1.08 539 5364 0.9462 0.997 0.911,1.09 533 5324
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.861 0.993 0.922,1.07 744 7420 0.8551 0.993 0.922,1.07 741 7359
800.4 Fracture of patella injuries & poisonings Both 0.2234 0.931 0.829,1.04 293 2904 0.2143 0.929 0.828,1.04 292 2875
801 Fracture of ankle and foot injuries & poisonings Both 0.2193 0.97 0.924,1.02 1804 17960 0.3981 0.971 0.908,1.04 908 9032
801.1 Fracture of foot injuries & poisonings Both 0.4295 0.973 0.91,1.04 913 9098 0.3981 0.971 0.908,1.04 908 9032
802 Fracture of pelvis injuries & poisonings Both 0.6138 1.03 0.918,1.16 321 3192 0.6095 1.03 0.918,1.16 320 3164
803 Fracture of upper limb injuries & poisonings Both 0.6067 0.987 0.938,1.04 1644 16288 0.471 1.04 0.938,1.15 418 4145
803.1 Fracture of humerus injuries & poisonings Both 0.7534 1.01 0.931,1.1 592 5913 0.7586 1.01 0.931,1.1 591 5881
803.2 Fracture of radius and ulna injuries & poisonings Both 0.7638 0.99 0.924,1.06 899 8929 0.9705 1.0 0.88,1.14 248 2464
803.21 Colles' fracture injuries & poisonings Both 0.9817 1.0 0.879,1.14 248 2475 0.9705 1.0 0.88,1.14 248 2464
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.5023 1.03 0.936,1.14 419 4190 0.471 1.04 0.938,1.15 418 4145
804 Fracture of hand or wrist injuries & poisonings Both 0.8954 0.996 0.94,1.06 1272 12504 0.9057 0.996 0.941,1.06 1270 12403
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.5458 1.02 0.957,1.09 1082 10755 0.4842 1.02 0.96,1.09 1076 10667
807 Fracture of ribs injuries & poisonings Both 0.1262 1.07 0.981,1.17 543 5428 0.1135 1.07 0.983,1.17 541 5378
809 Fracture of unspecified bones injuries & poisonings Both 0.3873 1.02 0.977,1.06 2426 23282 0.4074 1.02 0.976,1.06 2414 23100
817 Concussion injuries & poisonings Both 0.597 1.02 0.948,1.1 771 7696 0.6124 1.02 0.947,1.1 766 7656
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.3639 0.94 0.823,1.07 240 2380 0.6902 0.957 0.771,1.19 83 833
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.9183 0.988 0.779,1.25 74 740 0.9572 0.994 0.784,1.26 74 730
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.5861 0.942 0.76,1.17 84 837 0.6902 0.957 0.771,1.19 83 833
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.877 0.996 0.949,1.05 1782 17605 0.9594 1.0 0.954,1.05 1771 17454
830 Dislocation injuries & poisonings Both 0.5929 0.99 0.954,1.03 3129 28682 0.6637 0.992 0.956,1.03 3107 28476
835 Internal derangement of knee injuries & poisonings Both 0.4227 1.02 0.971,1.07 1774 17453 0.3784 1.02 0.973,1.07 1763 17317
836 Traumatic arthropathy injuries & poisonings Both 0.3459 1.05 0.95,1.16 423 4213 0.317 1.05 0.953,1.16 421 4185
840 Sprains and strains injuries & poisonings Both 0.3083 0.986 0.959,1.01 6106 31582 0.08913 0.963 0.922,1.01 2247 19399
840.1 Muscle/tendon sprain injuries & poisonings Both 0.3963 1.04 0.945,1.15 429 4269 0.3597 1.05 0.948,1.16 424 4230
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.4797 1.02 0.965,1.08 1343 13394 0.5649 1.02 0.961,1.08 1330 13286
840.3 Joint/ligament sprain injuries & poisonings Both 0.0871 0.963 0.922,1.01 2261 19530 0.08913 0.963 0.922,1.01 2247 19399
841 Sprains and strains of back and neck injuries & poisonings Both 0.2065 0.962 0.906,1.02 1175 11729 0.2265 0.963 0.907,1.02 1164 11665
842 Other sprains and strains injuries & poisonings Both 0.6209 1.02 0.954,1.08 1079 10729 0.6295 1.02 0.954,1.08 1069 10648
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.2904 0.974 0.928,1.02 1807 18037 0.2636 0.973 0.927,1.02 1790 17917
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.9268 0.997 0.926,1.07 797 7958 0.9036 0.995 0.925,1.07 792 7886
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.7161 1.02 0.92,1.13 398 3977 0.7621 1.02 0.916,1.13 393 3955
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.2985 0.973 0.923,1.02 1537 15333 0.2951 0.972 0.923,1.02 1523 15204
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.5105 1.04 0.917,1.19 254 2540 0.597 1.04 0.909,1.18 250 2524
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.6808 0.974 0.86,1.1 262 2617 0.6486 0.971 0.855,1.1 254 2594
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.07586 1.06 0.994,1.12 1196 11925 0.06607 1.06 0.996,1.12 1189 11853
858 Complication of internal orthopedic device injuries & poisonings Both 0.3556 1.02 0.975,1.07 1892 18846 0.3105 1.02 0.977,1.08 1887 18708
859 Complication due to other implant and internal device injuries & poisonings Both 0.514 0.984 0.937,1.03 1820 18191 0.5408 0.985 0.938,1.03 1813 18077
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.9141 0.998 0.963,1.03 3389 30552 0.1306 0.859 0.706,1.05 109 1164
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.1161 1.14 0.968,1.34 156 1551 0.1225 1.14 0.966,1.34 156 1541
870.2 Open wound of ear injuries & poisonings Both 0.9817 0.998 0.824,1.21 114 1131 0.984 1.0 0.827,1.21 114 1125
870.3 Other open wound of head and face injuries & poisonings Both 0.8299 1.01 0.945,1.07 1064 10560 0.811 1.01 0.946,1.07 1060 10485
870.4 Open wound of nose and sinus injuries & poisonings Both 0.7482 1.03 0.876,1.2 168 1667 0.7112 1.03 0.88,1.21 168 1654
870.5 Open wound of lip and mouth injuries & poisonings Both 0.9204 0.993 0.865,1.14 230 2293 0.879 0.989 0.862,1.14 228 2274
870.6 Open wound of neck injuries & poisonings Both 0.7656 0.978 0.843,1.13 184 1833 0.6223 0.963 0.83,1.12 181 1813
870.8 Open wound of genital organs injuries & poisonings Both 0.1186 0.86 0.712,1.04 117 1170 0.1306 0.859 0.706,1.05 109 1164
871 Open wounds of extremities injuries & poisonings Both 0.9036 1.0 0.964,1.04 2705 26585 0.9772 0.998 0.859,1.16 190 1882
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.3006 1.05 0.954,1.16 438 4378 0.3076 1.05 0.954,1.16 436 4353
871.2 Open wound of finger(s) injuries & poisonings Both 0.08318 0.936 0.868,1.01 731 7291 0.1069 0.94 0.872,1.01 725 7228
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.542 1.04 0.925,1.16 331 3277 0.6209 1.03 0.918,1.15 327 3251
871.4 Open wound of toe(s) injuries & poisonings Both 1.0 1.0 0.861,1.16 191 1901 0.9772 0.998 0.859,1.16 190 1882
872 Traumatic amputation injuries & poisonings Both 0.8356 0.989 0.895,1.09 415 4129 0.873 0.992 0.897,1.1 412 4086
873 Broken tooth injuries & poisonings Both 0.4898 0.945 0.804,1.11 148 1471 0.5082 0.946 0.804,1.11 145 1461
874 Complication of amputation stump injuries & poisonings Both 0.03311 0.826 0.693,0.984 122 1220 0.03631 0.828 0.695,0.988 122 1204
875 Non-healing surgical wound injuries & poisonings Both 0.3972 0.961 0.876,1.05 495 4950 0.3428 0.956 0.871,1.05 488 4918
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.2371 0.954 0.882,1.03 669 6680 0.3443 0.963 0.89,1.04 660 6632
907 Injuries to the nervous system injuries & poisonings Both 0.2291 0.959 0.895,1.03 888 8852 0.2704 0.962 0.898,1.03 885 8776
910 Superficial injury, infected injuries & poisonings Both 0.6295 0.947 0.759,1.18 89 887 0.6668 0.952 0.763,1.19 89 881
911 Blister injuries & poisonings Both 0.6887 0.97 0.834,1.13 185 1838 0.6982 0.971 0.835,1.13 185 1821
912 Insect bite injuries & poisonings Both 0.547 1.04 0.924,1.16 321 3207 0.5297 1.04 0.925,1.16 318 3178
913 Toxic effect of venom injuries & poisonings Both 0.09333 1.12 0.981,1.29 247 2461 0.07943 1.13 0.986,1.29 246 2447
915 Superficial injury without mention of infection injuries & poisonings Both 0.9506 1.0 0.96,1.04 2368 23457 0.9376 1.0 0.96,1.05 2354 23293
916 Contusion injuries & poisonings Both 0.1972 0.976 0.941,1.01 3199 30228 0.2099 0.977 0.942,1.01 3180 30017
930 Allergic reaction to food injuries & poisonings Both 0.4656 1.03 0.948,1.12 597 5953 0.4786 1.03 0.947,1.12 596 5922
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.2104 0.945 0.866,1.03 530 5290 0.1866 0.942 0.863,1.03 526 5258
938 Dermatitis due to solar radiation injuries & poisonings Both 0.2032 1.02 0.988,1.06 4197 24407 0.2965 1.02 0.984,1.05 3969 23839
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.01698 1.23 1.04,1.46 164 1640 0.01549 1.23 1.04,1.46 164 1634
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.2818 1.02 0.985,1.05 4001 24007 0.2965 1.02 0.984,1.05 3969 23839
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.3214 0.92 0.78,1.08 140 1400 0.3027 0.917 0.777,1.08 140 1393
942 Infusion and transfusion reaction injuries & poisonings Both 0.8511 1.01 0.881,1.17 221 2205 0.8035 1.02 0.884,1.17 217 2194
946 Anaphylactic shock NOS injuries & poisonings Both 0.455 1.04 0.935,1.16 385 3830 0.4266 1.04 0.938,1.16 384 3811
947 Urticaria injuries & poisonings Both 0.7621 0.989 0.923,1.06 889 8845 0.7674 0.99 0.924,1.06 887 8813
949 Allergies, other injuries & poisonings Both 0.3597 0.986 0.957,1.02 5269 26807 0.3048 0.984 0.955,1.01 5228 26614
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.6053 0.975 0.885,1.07 419 4176 0.6412 0.977 0.887,1.08 416 4144
957 Injury to other and unspecified nerves injuries & poisonings Both 0.7047 1.04 0.858,1.26 116 1150 0.6776 1.04 0.86,1.26 116 1140
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.3396 1.03 0.968,1.1 1073 10721 0.3767 1.1 0.887,1.37 91 903
958.1 Postoperative shock injuries & poisonings Both 0.05495 1.19 0.996,1.42 133 1325 0.05888 1.18 0.994,1.41 133 1316
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.4325 1.09 0.879,1.35 92 911 0.3767 1.1 0.887,1.37 91 903
960 Poisoning by antibiotics injuries & poisonings Both 0.865 0.996 0.952,1.04 2108 18753 0.861 1.0 0.951,1.06 1395 13787
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.2223 0.904 0.768,1.06 158 1552 0.1618 0.89 0.756,1.05 156 1543
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.8511 1.01 0.951,1.06 1414 13864 0.861 1.0 0.951,1.06 1395 13787
961 Poisoning by other anti-infectives injuries & poisonings Both 0.7311 1.02 0.924,1.12 470 4694 0.865 1.01 0.94,1.08 932 9146
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.8375 1.01 0.941,1.08 939 9190 0.865 1.01 0.94,1.08 932 9146
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.875 1.01 0.923,1.1 561 5601 0.9462 1.0 0.893,1.13 304 3007
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.7603 1.02 0.905,1.15 308 3069 0.6839 1.02 0.911,1.15 305 3046
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.9141 1.01 0.895,1.13 305 3029 0.9462 1.0 0.893,1.13 304 3007
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.4121 0.981 0.937,1.03 2031 19919 0.3524 0.978 0.934,1.02 1955 19387
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.4831 0.984 0.939,1.03 1980 19507 0.3524 0.978 0.934,1.02 1955 19387
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.826 1.01 0.925,1.1 538 5360 0.8913 1.01 0.919,1.1 502 5034
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.9484 1.0 0.916,1.1 509 5070 0.8913 1.01 0.919,1.1 502 5034
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.1368 0.945 0.878,1.02 753 7525 0.7211 1.04 0.842,1.28 98 964
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.871 0.995 0.94,1.05 1305 12848 0.8035 0.993 0.937,1.05 1296 12780
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.7295 1.04 0.841,1.28 98 967 0.7211 1.04 0.842,1.28 98 964
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.8299 1.02 0.822,1.28 86 850 0.7345 1.04 0.832,1.3 85 846
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.877 1.01 0.942,1.07 1000 9986 0.7586 1.01 0.946,1.08 997 9929
969 Poisoning by psychotropic agents injuries & poisonings Both 0.6887 1.03 0.897,1.18 234 2331 0.7328 1.02 0.893,1.18 233 2322
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.5152 1.09 0.835,1.43 56 546 0.5458 1.09 0.828,1.43 55 544
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.9247 1.01 0.88,1.15 228 2269 0.7852 1.03 0.826,1.29 86 850
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.1236 0.831 0.657,1.05 66 637 0.1208 0.83 0.656,1.05 66 630
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.7328 1.04 0.832,1.3 86 860 0.7852 1.03 0.826,1.29 86 850
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.6546 0.953 0.773,1.18 90 896 0.7145 0.962 0.779,1.19 89 884
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.9036 1.01 0.804,1.28 69 686 0.9376 1.01 0.798,1.28 68 678
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.1879 0.843 0.654,1.09 60 600 0.1905 0.843 0.654,1.09 60 597
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.6471 0.988 0.938,1.04 1565 14843 0.6281 0.987 0.937,1.04 1551 14747
979 Adverse drug events and drug allergies injuries & poisonings Both 0.4295 1.02 0.973,1.07 2116 20636 0.3972 1.02 0.975,1.07 2102 20525
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.4121 1.09 0.883,1.36 91 904 0.4093 1.09 0.883,1.36 91 900
990 Effects radiation NOS injuries & poisonings Both 0.7328 1.01 0.968,1.05 2707 23906 0.7925 1.01 0.966,1.05 2657 23749
994 Sepsis and SIRS injuries & poisonings Both 0.8185 0.994 0.946,1.04 1724 17160 0.7834 0.987 0.899,1.08 479 4803
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.3733 1.06 0.932,1.21 248 2472 0.3673 1.06 0.933,1.21 248 2450
994.2 Sepsis injuries & poisonings Both 0.8892 0.996 0.947,1.05 1636 16281 0.7834 0.987 0.899,1.08 479 4803
994.21 Septic shock injuries & poisonings Both 0.8356 0.99 0.902,1.09 484 4840 0.7834 0.987 0.899,1.08 479 4803
1000 Burns injuries & poisonings Both 0.3327 0.961 0.887,1.04 638 6350 0.375 0.964 0.89,1.04 636 6315
1001 Foreign body injury injuries & poisonings Both 0.06761 0.962 0.922,1.0 2372 22762 0.08318 0.963 0.924,1.0 2351 22529
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.05012 1.03 1.0,1.06 4830 32603 0.0537 1.03 1.0,1.06 4786 32373
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.4178 1.03 0.965,1.09 1136 11344 0.5458 1.02 0.958,1.08 1116 11271
1005 Other symptoms injuries & poisonings Both 0.875 1.0 0.977,1.03 7724 30626 0.9099 1.0 0.977,1.03 7678 30396
1006 Crushing injury injuries & poisonings Both 0.2018 1.09 0.956,1.24 245 2437 0.1892 1.09 0.958,1.24 244 2411
1007 Injury to blood vessels injuries & poisonings Both 0.1614 1.07 0.972,1.19 411 4106 0.1614 1.07 0.972,1.19 406 4068
1008 Crushing or internal injury to organs injuries & poisonings Both 0.26 1.04 0.972,1.11 934 9331 0.2512 1.04 0.972,1.11 927 9257
1009 Injury, NOS injuries & poisonings Both 0.0302 0.975 0.952,0.998 9284 29063 0.02884 0.974 0.952,0.997 9228 28843
1010 Other tests injuries & poisonings Both 0.2992 1.01 0.991,1.03 19027 19331 0.3681 1.01 0.989,1.03 18874 19208
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.01413 1.04 1.01,1.06 5922 32336 0.02344 1.03 1.0,1.06 5865 32117
1012 Late effect injuries & poisonings Both 0.984 1.0 0.93,1.08 792 7909 0.9247 1.0 0.933,1.08 788 7837
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.5929 0.989 0.949,1.03 2459 23709 0.6053 0.989 0.949,1.03 2442 23523
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3581 0.93 0.797,1.09 177 1770 0.3707 0.932 0.799,1.09 177 1762
1015 Effects of other external causes injuries & poisonings Both 0.2541 1.02 0.988,1.05 5744 32595 0.2203 1.02 0.989,1.05 5714 32349
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.875 0.996 0.954,1.04 2208 21537 0.8995 0.997 0.954,1.04 2199 21373
1100 Family history injuries & poisonings Both 0.1828 0.911 0.795,1.04 222 2220 0.1991 0.914 0.797,1.05 219 2206
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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