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MGI PRS for Breast cancer [female](174.1) based on GWAS Catalog (2019-05-03)
GWAS reference: 17529967;17529973;17529974.... GWAS source: GWAS Catalog (2019-05-03) PRS method: P_5e-08
PRSweb LD reference: MGI GWAS phenotype: Breast cancer;Breast cancer (estrogen-receptor negative);Bre... PRSweb date: 2020-06-20
GWAS ID: GWAS_Catalog_r2019-05-03_X174.1 GWAS URL: https://www.ebi.ac.uk/gwas Genome build: GRCh37/hg19
PRS tuning parameter: P<=5e-08 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.5875 0.988 0.947,1.03 2317 23065 0.4932 1.02 0.956,1.1 890 8777
008.5 Bacterial enteritis infectious diseases Both 0.9931 1.0 0.939,1.06 1090 10875 0.6622 1.02 0.945,1.09 830 8240
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.9954 1.0 0.933,1.07 896 8939 0.6622 1.02 0.945,1.09 830 8240
008.6 Viral Enteritis infectious diseases Both 0.5188 0.973 0.896,1.06 590 5900 0.5105 0.971 0.891,1.06 541 5407
010 Tuberculosis infectious diseases Both 0.5848 1.04 0.901,1.2 195 1948 0.3451 0.99 0.97,1.01 17301 18363
031 Diseases due to other mycobacteria infectious diseases Both 0.8913 1.02 0.804,1.28 73 722 0.631 0.939 0.728,1.21 64 662
038 Septicemia infectious diseases Both 0.1746 1.03 0.986,1.08 2043 20052 0.1081 1.06 0.988,1.13 892 8935
038.1 Gram negative septicemia infectious diseases Both 0.597 0.974 0.884,1.07 459 4559 0.5333 0.969 0.877,1.07 432 4297
038.2 Gram positive septicemia infectious diseases Both 0.06918 1.15 0.989,1.34 184 1840 0.07244 1.15 0.988,1.34 179 1742
038.3 Bacteremia infectious diseases Both 0.2223 1.04 0.975,1.11 955 9489 0.1081 1.06 0.988,1.13 892 8935
041 Bacterial infection NOS infectious diseases Both 0.05623 1.03 0.999,1.06 4641 32299 0.9057 0.992 0.864,1.14 223 2097
041.1 Staphylococcus infections infectious diseases Both 0.05248 1.06 0.999,1.12 1390 13828 0.2871 1.05 0.963,1.14 606 5916
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.07413 1.07 0.993,1.16 714 7071 0.1445 1.06 0.98,1.15 663 6662
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.3006 1.04 0.963,1.13 639 6376 0.2871 1.05 0.963,1.14 606 5916
041.2 Streptococcus infection infectious diseases Both 0.2084 1.04 0.98,1.1 1316 13131 0.08128 0.872 0.748,1.02 191 1862
041.21 Rheumatic fever / chorea infectious diseases Both 0.06607 0.871 0.751,1.01 205 2047 0.08128 0.872 0.748,1.02 191 1862
041.4 E. coli infectious diseases Both 0.3069 1.04 0.968,1.11 949 9462 0.2985 1.04 0.967,1.11 864 8577
041.8 H. pylori infectious diseases Both 0.9441 1.01 0.867,1.17 190 1892 0.9247 1.01 0.862,1.18 176 1738
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.6546 0.97 0.847,1.11 228 2265 0.9057 0.992 0.864,1.14 223 2097
053 Herpes zoster infectious diseases Both 0.004677 1.09 1.03,1.16 1184 11746 0.975 1.0 0.847,1.19 148 1481
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.859 1.01 0.866,1.19 166 1655 0.975 1.0 0.847,1.19 148 1481
054 Herpes simplex infectious diseases Both 0.2153 1.04 0.979,1.1 1235 12278 0.7638 1.01 0.949,1.07 1094 11148
070 Viral hepatitis infectious diseases Both 0.826 1.01 0.932,1.09 661 6584 0.0389 1.08 1.0,1.15 861 8655
070.1 Viral hepatitis A infectious diseases Both 0.9141 0.986 0.758,1.28 67 660 0.8279 0.97 0.738,1.28 61 607
070.2 Viral hepatitis B infectious diseases Both 0.5272 1.05 0.899,1.23 162 1620 0.597 1.04 0.888,1.23 151 1499
070.3 Viral hepatitis C infectious diseases Both 0.52 1.03 0.936,1.14 439 4366 0.4217 1.04 0.943,1.15 428 4105
070.4 Chronic hepatitis infectious diseases Both 0.9572 1.0 0.857,1.18 161 1610 0.7295 1.03 0.875,1.21 153 1509
070.9 Hepatitis NOS infectious diseases Both 0.05754 1.07 0.998,1.14 924 9231 0.0389 1.08 1.0,1.15 861 8655
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.9616 1.0 0.838,1.2 122 1220 0.8892 1.01 0.826,1.25 94 915
071.1 HIV infection, symptomatic infectious diseases Both 0.8913 0.986 0.804,1.21 95 950 0.8892 1.01 0.826,1.25 94 915
078 Viral warts & HPV infectious diseases Both 0.6039 1.01 0.971,1.05 2651 24185 0.8166 1.0 0.964,1.05 2423 22379
079 Viral infection infectious diseases Both 0.8995 0.998 0.969,1.03 5061 29504 0.7745 1.01 0.928,1.11 530 5323
079.1 Varicella infection infectious diseases Both 0.4932 1.01 0.976,1.05 2940 25647 0.9572 1.0 0.962,1.04 2631 23755
079.2 Infectious mononucleosis infectious diseases Both 0.3281 0.933 0.811,1.07 213 2093 0.3112 0.93 0.808,1.07 207 1978
079.9 Viremia, NOS infectious diseases Both 0.9397 1.0 0.921,1.09 579 5713 0.7745 1.01 0.928,1.11 530 5323
080 Postoperative infection infectious diseases Both 0.1045 1.03 0.993,1.08 2586 25769 0.2223 1.03 0.984,1.07 2263 23809
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.7907 1.01 0.953,1.07 1364 13616 0.8995 0.996 0.939,1.06 1225 12707
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.5623 0.977 0.905,1.06 700 6990 0.4285 0.968 0.894,1.05 654 6467
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.5888 1.01 0.97,1.06 2379 23308 0.6095 1.04 0.896,1.21 195 1998
110.1 Dermatophytosis infectious diseases Both 0.3524 1.02 0.977,1.07 2164 21163 0.778 0.987 0.904,1.08 527 5357
110.11 Dermatophytosis of nail infectious diseases Both 0.2618 1.03 0.976,1.09 1264 12489 0.2366 1.04 0.976,1.1 1162 11552
110.12 Althete's foot infectious diseases Both 0.8091 0.99 0.91,1.08 593 5884 0.6592 0.981 0.899,1.07 557 5539
110.13 Dermatophytosis of the body infectious diseases Both 0.859 0.992 0.911,1.08 570 5682 0.778 0.987 0.904,1.08 527 5357
110.2 Dermatomycoses infectious diseases Both 0.1138 0.906 0.802,1.02 283 2812 0.104 0.901 0.794,1.02 265 2647
112 Candidiasis infectious diseases Both 0.05754 1.04 0.999,1.08 2931 25310 0.2742 1.05 0.96,1.16 482 4832
112.3 Candidiasis of skin and nails infectious diseases Both 0.5728 1.03 0.94,1.12 546 5450 0.2742 1.05 0.96,1.16 482 4832
117 Mycoses infectious diseases Both 0.1986 1.06 0.969,1.16 494 4925 0.1259 1.18 0.955,1.45 101 970
117.1 Histoplasmosis infectious diseases Both 0.5546 1.08 0.837,1.39 66 660 0.6281 1.07 0.82,1.39 59 608
117.4 Aspergillosis infectious diseases Both 0.1183 1.18 0.959,1.44 105 1045 0.1259 1.18 0.955,1.45 101 970
130 Spirochetal infection infectious diseases Both 0.8831 1.01 0.844,1.22 118 1177 0.5623 0.935 0.746,1.17 80 774
130.1 Lyme disease infectious diseases Both 0.5483 0.936 0.754,1.16 86 860 0.5623 0.935 0.746,1.17 80 774
132 Infestation (lice, mites) infectious diseases Both 0.6281 0.959 0.811,1.13 146 1460 0.7031 0.967 0.814,1.15 136 1369
134 Helminthiases infectious diseases Both 0.6353 0.935 0.71,1.23 54 540 ,
136 Other infectious and parasitic diseases infectious diseases Both 0.2004 1.03 0.986,1.07 2438 24314 0.2438 1.03 0.982,1.07 2211 22425
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.2924 1.03 0.973,1.1 1166 11657 0.2897 1.03 0.972,1.1 1111 10994
145 Cancer of mouth neoplasms Both 0.8551 1.01 0.947,1.07 1182 11759 0.5023 1.06 0.902,1.23 163 1596
145.1 Cancer of lip neoplasms Both 0.7762 1.04 0.815,1.32 69 690 0.8851 1.02 0.798,1.3 66 649
145.2 Cancer of tongue neoplasms Both 0.2965 1.05 0.96,1.14 550 5486 0.2864 1.05 0.96,1.15 534 5217
145.3 Cancer of major salivary glands neoplasms Both 0.8551 1.01 0.9,1.13 310 3093 0.879 0.991 0.879,1.12 291 2902
145.4 Cancer of the gums neoplasms Both 0.5458 0.949 0.801,1.12 143 1419 0.4395 0.933 0.782,1.11 134 1260
145.5 Cancer of the mouth floor neoplasms Both 0.5358 1.05 0.901,1.22 173 1723 0.5023 1.06 0.902,1.23 163 1596
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.826 0.993 0.934,1.06 1124 11202 0.8433 0.986 0.855,1.14 198 1912
149.1 Cancer of oropharynx neoplasms Both 0.4111 1.05 0.932,1.19 291 2892 0.2692 1.07 0.949,1.21 284 2790
149.2 Cancer of nasopharynx neoplasms Both 0.3319 0.896 0.719,1.12 87 855 0.1622 0.833 0.645,1.08 64 780
149.3 Cancer of hypopharynx neoplasms Both 0.6237 1.06 0.832,1.36 68 680 0.547 1.08 0.843,1.38 67 656
149.4 Cancer of larynx neoplasms Both 0.3404 0.946 0.845,1.06 332 3314 0.3508 0.948 0.846,1.06 327 3205
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.7727 1.01 0.925,1.11 505 5041 0.9183 1.0 0.915,1.1 482 4748
149.9 Cancer of of nasal cavities neoplasms Both 0.8933 0.99 0.862,1.14 208 2067 0.8433 0.986 0.855,1.14 198 1912
150 Cancer of esophagus neoplasms Both 0.4335 1.04 0.938,1.16 378 3776 0.9441 0.996 0.891,1.11 344 3620
151 Cancer of stomach neoplasms Both 0.7161 1.02 0.922,1.13 430 4292 0.6622 1.02 0.923,1.13 405 4049
153 Colorectal cancer neoplasms Both 0.3236 0.971 0.915,1.03 1196 11882 0.9162 1.0 0.925,1.09 615 6139
153.2 Colon cancer neoplasms Both 0.1 0.945 0.884,1.01 941 9327 0.1614 0.951 0.887,1.02 870 8671
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.9226 0.996 0.92,1.08 669 6663 0.9162 1.0 0.925,1.09 615 6139
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.743 0.983 0.89,1.09 418 4180 0.6607 1.03 0.909,1.16 265 2661
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.7621 1.02 0.904,1.15 285 2850 0.6607 1.03 0.909,1.16 265 2661
157 Pancreatic cancer neoplasms Both 0.9863 0.999 0.905,1.1 430 4292 0.7907 1.01 0.915,1.12 406 3983
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.1986 1.04 0.981,1.1 1369 13455 0.2355 1.04 0.977,1.1 1239 12354
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.5236 1.02 0.952,1.1 779 7785 0.3319 1.07 0.934,1.22 221 2291
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.4529 1.06 0.912,1.23 183 1830 0.3715 1.07 0.918,1.26 164 1689
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.2951 0.91 0.763,1.09 133 1330 0.5794 0.951 0.794,1.14 128 1239
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.5598 1.04 0.916,1.18 255 2550 0.3319 1.07 0.934,1.22 221 2291
164 Cancer of intrathoracic organs neoplasms Both 0.1262 1.16 0.959,1.4 111 1110 0.1936 1.16 0.928,1.44 80 1036
165 Cancer within the respiratory system neoplasms Both 0.3855 1.03 0.963,1.1 945 9436 0.7727 1.01 0.94,1.09 795 8124
165.1 Cancer of bronchus; lung neoplasms Both 0.743 1.01 0.944,1.08 874 8724 0.7727 1.01 0.94,1.09 795 8124
170 Cancer of bone and connective tissue neoplasms Both 0.5521 1.02 0.964,1.07 1538 15304 0.8954 1.0 0.941,1.07 982 10190
170.1 Bone cancer neoplasms Both 0.6637 1.02 0.941,1.1 668 6660 0.6902 1.02 0.936,1.1 601 6169
170.2 Cancer of connective tissue neoplasms Both 0.6839 1.01 0.952,1.08 1097 10941 0.8954 1.0 0.941,1.07 982 10190
172 Skin cancer neoplasms Both 0.7551 1.0 0.977,1.03 7099 27878 0.1542 1.05 0.983,1.11 1120 9586
172.1 Melanomas of skin, dx or hx neoplasms Both 0.3304 0.98 0.942,1.02 2701 21867 0.3673 0.981 0.94,1.02 2452 20039
172.11 Melanomas of skin neoplasms Both 0.2992 0.979 0.94,1.02 2624 21526 0.3673 0.981 0.94,1.02 2452 20039
172.2 Other non-epithelial cancer of skin neoplasms Both 0.6368 1.01 0.978,1.04 5888 25669 0.07943 1.05 0.995,1.1 1789 13623
172.21 Basal cell carcinoma neoplasms Both 0.3273 0.981 0.943,1.02 2988 20068 0.2999 0.979 0.939,1.02 2726 18477
172.22 Squamous cell carcinoma neoplasms Both 0.1225 1.04 0.99,1.09 1917 14585 0.07943 1.05 0.995,1.1 1789 13623
172.3 Carcinoma in situ of skin neoplasms Both 0.1914 1.04 0.98,1.11 1215 10290 0.1542 1.05 0.983,1.11 1120 9586
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.8054 0.994 0.943,1.05 1575 15093 0.9141 1.0 0.95,1.06 1423 13874
174 Breast cancer neoplasms Both 6.31E-54 1.4 1.34,1.46 2694 13131 ,
174.1 Breast cancer [female] neoplasms Female 1.995E-55 1.41 1.35,1.48 2605 12548 ,
174.11 Malignant neoplasm of female breast neoplasms Female 5.012E-55 1.42 1.36,1.48 2565 12510 ,
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.00257 1.24 1.08,1.43 206 2051 ,
175 Acquired absence of breast neoplasms Female 2.512E-19 1.36 1.27,1.45 978 9172 0.0955 0.824 0.657,1.03 72 9172
180 Cervical cancer and dysplasia neoplasms Female 0.08128 1.06 0.993,1.12 1182 10494 0.5861 1.02 0.948,1.1 770 7886
180.1 Cervical cancer neoplasms Female 0.133 1.08 0.977,1.19 430 4300 0.5346 1.03 0.93,1.15 362 4300
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.1178 1.06 0.986,1.14 857 7886 0.5861 1.02 0.948,1.1 770 7886
182 Malignant neoplasm of uterus neoplasms Female 0.6776 1.02 0.938,1.1 643 6390 0.6081 0.978 0.897,1.07 559 6390
184 Cancer of other female genital organs neoplasms Female 0.01738 1.09 1.01,1.16 910 8957 0.879 0.993 0.901,1.09 446 5253
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.00871 1.13 1.03,1.24 491 4888 0.9727 1.0 0.889,1.13 292 3659
184.11 Malignant neoplasm of ovary neoplasms Female 0.2582 1.06 0.955,1.19 367 3659 0.9727 1.0 0.889,1.13 292 3659
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.2382 1.06 0.965,1.15 526 5253 0.879 0.993 0.901,1.09 446 5253
185 Cancer of prostate neoplasms Male 0.004677 0.934 0.891,0.979 2432 8825 0.003236 0.932 0.889,0.977 2424 8793
187 Cancer of other male genital organs neoplasms Male 0.879 0.99 0.876,1.12 276 2723 0.271 1.1 0.928,1.3 143 1385
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.3784 0.911 0.74,1.12 96 960 0.3802 0.912 0.741,1.12 96 956
187.2 Malignant neoplasm of testis neoplasms Male 0.2291 1.11 0.936,1.32 144 1387 0.271 1.1 0.928,1.3 143 1385
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.8279 0.995 0.955,1.04 2552 20553 0.6397 0.98 0.9,1.07 582 5576
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.5916 0.984 0.929,1.04 1261 12588 0.873 0.988 0.856,1.14 199 1900
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.3698 0.972 0.913,1.03 1083 10823 0.3846 0.972 0.912,1.04 1054 10185
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.8551 0.987 0.855,1.14 202 2010 0.873 0.988 0.856,1.14 199 1900
189.2 Cancer of bladder neoplasms Both 0.9638 1.0 0.95,1.06 1575 13516 0.597 0.985 0.932,1.04 1406 11951
189.21 Malignant neoplasm of bladder neoplasms Both 0.7015 0.989 0.937,1.04 1456 12558 0.597 0.985 0.932,1.04 1406 11951
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.6501 0.981 0.902,1.07 601 5841 0.6397 0.98 0.9,1.07 582 5576
190 Cancer of eye neoplasms Both 0.6295 1.05 0.867,1.27 114 1125 0.7178 1.04 0.852,1.26 105 1047
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.3192 1.03 0.967,1.11 904 9040 0.4266 1.04 0.944,1.15 426 4540
191.1 Cancer of brain and nervous system neoplasms Both 0.1279 1.07 0.981,1.16 580 5800 0.4266 1.04 0.944,1.15 426 4540
191.11 Cancer of brain neoplasms Both 0.3864 1.04 0.95,1.14 483 4830 0.4266 1.04 0.944,1.15 426 4540
193 Thyroid cancer neoplasms Both 0.3412 0.966 0.898,1.04 798 7953 0.2685 0.958 0.889,1.03 731 7207
194 Cancer of other endocrine glands neoplasms Both 0.1288 1.11 0.97,1.27 221 2207 0.1132 1.12 0.973,1.3 195 2042
195 Cancer, suspected or other neoplasms Both 2.63E-7 1.06 1.04,1.09 12134 23141 0.3733 1.03 0.964,1.1 932 8810
195.1 Malignant neoplasm, other neoplasms Both 6.607E-7 1.06 1.04,1.09 11693 23098 0.3192 1.01 0.988,1.04 9945 22543
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.1143 1.05 0.987,1.13 970 8963 0.3733 1.03 0.964,1.1 932 8810
196 Radiotherapy neoplasms Both 8.913E-9 1.15 1.09,1.2 2067 15612 0.4613 1.02 0.965,1.08 1343 15136
197 Chemotherapy neoplasms Both 5.012E-7 1.09 1.05,1.13 4051 21210 0.1683 1.03 0.989,1.07 3137 20661
198 Secondary malignant neoplasm neoplasms Both 3.467E-6 1.08 1.04,1.11 4986 21474 0.9484 1.0 0.878,1.15 240 2671
198.1 Secondary malignancy of lymph nodes neoplasms Both 4.677E-6 1.09 1.05,1.14 3156 19844 0.0631 1.04 0.998,1.08 2626 19307
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.2014 1.05 0.976,1.12 903 8847 0.5636 1.02 0.95,1.1 793 8634
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.004365 1.12 1.04,1.21 725 7166 0.03236 1.09 1.01,1.18 649 6938
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.5702 1.02 0.944,1.11 643 6395 0.9376 1.0 0.919,1.1 537 6233
198.5 Secondary malignancy of brain/spine neoplasms Both 0.3112 1.05 0.958,1.14 545 5421 0.6252 1.02 0.93,1.13 453 5273
198.6 Secondary malignancy of bone neoplasms Both 0.04365 1.08 1.0,1.17 712 6962 0.1936 1.06 0.972,1.15 576 6768
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.3141 1.07 0.942,1.21 287 2752 0.9484 1.0 0.878,1.15 240 2671
199 Neoplasm of uncertain behavior neoplasms Both 0.08913 1.03 0.996,1.06 4947 22823 0.5715 0.933 0.734,1.19 68 703
199.4 Neurofibromatosis neoplasms Both 0.5715 0.934 0.737,1.18 72 720 0.5715 0.933 0.734,1.19 68 703
200 Myeloproliferative disease neoplasms Both 0.5082 1.02 0.956,1.1 886 8851 0.4977 0.944 0.8,1.11 155 1543
200.1 Polycythemia vera neoplasms Both 0.5741 0.954 0.81,1.12 161 1610 0.4977 0.944 0.8,1.11 155 1543
201 Hodgkin's disease neoplasms Both 0.2291 1.11 0.936,1.32 138 1373 0.5047 1.07 0.883,1.29 114 1273
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.08318 1.05 0.994,1.11 1308 13070 0.1824 0.885 0.739,1.06 123 1231
202.2 Non-Hodgkins lymphoma neoplasms Both 0.06607 1.06 0.996,1.13 1141 11402 0.1824 0.885 0.739,1.06 123 1231
202.21 Nodular lymphoma neoplasms Both 0.0257 1.1 1.01,1.19 632 6320 0.4083 1.04 0.946,1.14 458 5800
202.22 Reticulosarcoma neoplasms Both 0.5508 0.95 0.801,1.13 137 1355 0.4634 0.936 0.785,1.12 127 1276
202.24 Large cell lymphoma neoplasms Both 0.2249 0.897 0.753,1.07 132 1300 0.1824 0.885 0.739,1.06 123 1231
204 Leukemia neoplasms Both 0.0389 1.1 1.0,1.2 545 5450 0.6516 1.04 0.886,1.21 168 1689
204.1 Lymphoid leukemia neoplasms Both 0.7211 1.03 0.885,1.19 187 1870 0.1778 1.13 0.946,1.35 132 1272
204.11 Lymphoid leukemia, acute neoplasms Both 0.6982 0.949 0.727,1.24 58 580 ,
204.12 Lymphoid leukemia, chronic neoplasms Both 0.2606 1.11 0.928,1.32 136 1350 0.1778 1.13 0.946,1.35 132 1272
204.2 Myeloid leukemia neoplasms Both 0.00537 1.22 1.06,1.41 206 2060 0.2249 1.12 0.931,1.36 111 1169
204.21 Myeloid leukemia, acute neoplasms Both 0.2979 1.1 0.919,1.32 124 1240 0.2249 1.12 0.931,1.36 111 1169
204.4 Multiple myeloma neoplasms Both 0.867 0.987 0.847,1.15 180 1795 0.6516 1.04 0.886,1.21 168 1689
208 Benign neoplasm of colon neoplasms Both 0.6081 0.993 0.969,1.02 8098 29324 0.5321 0.992 0.966,1.02 7393 27364
209 Neuroendocrine tumors neoplasms Both 0.1535 1.1 0.963,1.27 222 2220 0.2 1.1 0.952,1.27 204 2054
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.5957 0.986 0.936,1.04 1584 15798 0.8995 0.997 0.945,1.05 1508 14769
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.9462 0.999 0.971,1.03 5807 30296 0.7834 1.0 0.975,1.03 5398 28208
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.6998 1.01 0.959,1.06 1556 15533 0.4932 1.02 0.966,1.08 1472 14511
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.1977 0.965 0.913,1.02 1405 13304 0.1374 0.958 0.906,1.01 1330 12768
214 Lipoma neoplasms Both 0.342 0.971 0.913,1.03 1117 11124 0.08913 0.93 0.856,1.01 609 6208
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.1644 0.946 0.875,1.02 681 6793 0.08913 0.93 0.856,1.01 609 6208
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.4603 1.01 0.979,1.05 3594 32904 0.7129 1.01 0.971,1.04 3283 30576
216 Benign neoplasm of skin neoplasms Both 0.3864 1.01 0.987,1.03 9073 29036 0.8472 1.02 0.834,1.25 94 986
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.869 0.984 0.815,1.19 111 1093 0.8472 1.02 0.834,1.25 94 986
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.9016 1.0 0.945,1.07 1150 11417 0.4853 0.976 0.913,1.04 937 9699
217.1 Nevus, non-neoplastic neoplasms Both 0.8892 1.0 0.943,1.07 1063 10579 0.4853 0.976 0.913,1.04 937 9699
218 Benign neoplasm of uterus neoplasms Female 0.6339 1.01 0.973,1.05 3552 13845 0.2339 0.974 0.932,1.02 2433 12044
218.1 Uterine leiomyoma neoplasms Female 0.9462 0.998 0.946,1.05 1506 13465 0.3733 0.974 0.919,1.03 1279 11800
218.2 Other benign neoplasm of uterus neoplasms Female 0.8954 1.0 0.963,1.04 2824 13698 0.2339 0.974 0.932,1.02 2433 12044
220 Benign neoplasm of ovary neoplasms Female 0.2692 1.04 0.968,1.12 763 7571 0.2193 0.949 0.872,1.03 586 7571
221 Benign neoplasm of other female genital organs neoplasms Female 0.08318 1.05 0.994,1.1 1666 12074 0.4188 0.977 0.925,1.03 1412 12074
222 Benign neoplasm of male genital organs neoplasms Male 0.06918 0.94 0.879,1.0 954 9116 0.05623 0.937 0.876,1.0 949 9084
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.1671 1.04 0.984,1.1 1547 11080 0.195 1.04 0.982,1.09 1493 10600
224 Benign neoplasm of eye neoplasms Both 0.5176 0.97 0.885,1.06 511 5062 0.8872 0.992 0.891,1.11 373 3857
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.8356 0.989 0.895,1.09 429 4230 0.8872 0.992 0.891,1.11 373 3857
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.4667 1.02 0.961,1.09 1039 10379 0.8472 1.01 0.881,1.17 212 2242
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.6442 1.02 0.947,1.09 817 8160 0.3954 1.03 0.959,1.11 762 7488
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.8995 1.01 0.884,1.15 242 2420 0.8472 1.01 0.881,1.17 212 2242
226 Benign neoplasm of thyroid glands neoplasms Both 0.912 0.997 0.936,1.06 1082 10810 0.6039 0.983 0.92,1.05 978 9679
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.7586 0.991 0.938,1.05 1387 13870 0.6412 1.03 0.921,1.14 354 3441
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.9183 0.994 0.895,1.1 375 3745 0.826 1.01 0.908,1.13 347 3432
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.537 0.975 0.899,1.06 644 6434 0.8492 0.992 0.911,1.08 598 5682
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.6683 1.02 0.921,1.14 373 3724 0.6412 1.03 0.921,1.14 354 3441
228 Hemangioma and lymphangioma, any site neoplasms Both 0.3083 1.03 0.975,1.08 1517 15150 0.7129 1.01 0.941,1.09 743 7700
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.3908 1.03 0.961,1.11 849 8478 0.7129 1.01 0.941,1.09 743 7700
229 Benign neoplasm of unspecified sites neoplasms Both 0.05129 1.03 1.0,1.05 6631 31223 0.631 0.992 0.959,1.03 3977 28113
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.01072 1.04 1.01,1.07 4904 29712 0.631 0.992 0.959,1.03 3977 28113
860 Bone marrow or stem cell transplant neoplasms Both 0.166 1.14 0.948,1.37 127 1266 0.3076 1.1 0.912,1.34 116 1201
240 Simple and unspecified goiter endocrine/metabolic Both 0.526 0.976 0.906,1.05 767 7647 0.3467 0.963 0.889,1.04 676 6776
241 Nontoxic nodular goiter endocrine/metabolic Both 0.0955 0.963 0.922,1.01 2274 18240 0.08128 0.94 0.876,1.01 874 8867
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.4688 0.982 0.935,1.03 1795 16440 0.2667 0.971 0.921,1.02 1568 14781
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.3459 0.969 0.909,1.03 1017 10065 0.08128 0.94 0.876,1.01 874 8867
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.7345 0.989 0.929,1.05 1075 10635 0.8166 0.977 0.802,1.19 107 1035
242.1 Graves' disease endocrine/metabolic Both 0.0389 0.897 0.808,0.995 399 3965 0.05623 0.898 0.804,1.0 354 3557
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.8072 1.03 0.833,1.26 98 978 0.9204 0.989 0.794,1.23 87 877
242.3 Exophthalmos endocrine/metabolic Both 0.4819 0.954 0.837,1.09 245 2447 0.8166 0.977 0.802,1.19 107 1035
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.5689 0.947 0.785,1.14 116 1160 0.8166 0.977 0.802,1.19 107 1035
244 Hypothyroidism endocrine/metabolic Both 0.14 0.979 0.952,1.01 6448 27183 0.2427 0.982 0.952,1.01 5369 25001
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.09772 0.955 0.904,1.01 1421 14153 0.04571 0.943 0.89,0.999 1282 12788
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.3206 0.965 0.9,1.03 853 8502 0.3062 0.962 0.894,1.04 765 7638
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.3273 0.986 0.958,1.01 5996 26719 0.2427 0.982 0.952,1.01 5369 25001
245 Thyroiditis endocrine/metabolic Both 0.6622 0.981 0.9,1.07 574 5720 0.5768 0.971 0.876,1.08 402 3993
245.2 Chronic thyroiditis endocrine/metabolic Both 0.6823 0.98 0.89,1.08 463 4617 0.5768 0.971 0.876,1.08 402 3993
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.5929 0.974 0.884,1.07 456 4533 0.5768 0.971 0.876,1.08 402 3993
246 Other disorders of thyroid endocrine/metabolic Both 0.03802 0.968 0.938,0.998 5018 25158 0.1644 0.938 0.857,1.03 517 5121
246.2 Thyroid cyst endocrine/metabolic Both 0.04898 0.798 0.637,0.999 83 804 0.02884 0.753 0.584,0.972 66 709
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.166 0.941 0.863,1.03 568 5651 0.1644 0.938 0.857,1.03 517 5121
249 Secondary diabetes mellitus endocrine/metabolic Both 0.1161 1.07 0.984,1.15 686 6849 0.06457 1.08 0.995,1.17 647 6450
250 Diabetes mellitus endocrine/metabolic Both 0.857 0.998 0.975,1.02 10115 27568 0.1493 1.06 0.98,1.14 754 7567
250.1 Type 1 diabetes endocrine/metabolic Both 0.3981 1.03 0.965,1.09 1053 10521 0.6486 1.06 0.824,1.36 68 648
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.2972 0.885 0.704,1.11 80 792 0.5023 0.923 0.731,1.17 77 738
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.03802 1.15 1.01,1.32 235 2346 0.01047 1.2 1.04,1.37 224 2185
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.1905 1.08 0.96,1.23 280 2800 0.1837 1.09 0.96,1.24 263 2613
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.2065 1.09 0.954,1.24 238 2372 0.07244 1.13 0.988,1.3 224 2225
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.7499 1.04 0.815,1.33 70 690 0.6486 1.06 0.824,1.36 68 648
250.2 Type 2 diabetes endocrine/metabolic Both 0.542 0.992 0.965,1.02 7035 26169 0.2495 1.06 0.962,1.16 487 4803
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.3524 1.09 0.906,1.32 120 1200 0.2213 1.13 0.931,1.36 116 1121
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.2432 1.04 0.976,1.1 1133 11056 0.246 1.04 0.975,1.11 1065 10351
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.2541 1.04 0.97,1.12 826 8208 0.2037 1.05 0.974,1.13 756 7584
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.9616 0.999 0.946,1.05 1419 13969 0.6982 1.01 0.956,1.07 1328 12998
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.5176 1.03 0.941,1.13 513 5077 0.2495 1.06 0.962,1.16 487 4803
250.3 Insulin pump user endocrine/metabolic Both 0.9908 1.0 0.954,1.05 1884 17814 0.7031 1.01 0.962,1.06 1771 16520
250.4 Abnormal glucose endocrine/metabolic Both 0.3631 1.01 0.984,1.04 5404 26451 0.6653 1.01 0.975,1.04 4322 23943
250.41 Impaired fasting glucose endocrine/metabolic Both 0.1567 1.04 0.984,1.1 1326 13130 0.2432 1.04 0.976,1.1 1182 11955
250.42 Other abnormal glucose endocrine/metabolic Both 0.6281 1.01 0.977,1.04 4736 25883 0.6653 1.01 0.975,1.04 4322 23943
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.6668 0.95 0.754,1.2 78 747 0.6281 0.942 0.74,1.2 73 685
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.9057 0.996 0.937,1.06 1137 11335 0.7674 1.01 0.948,1.08 1071 10590
250.7 Diabetic retinopathy endocrine/metabolic Both 0.1285 1.06 0.984,1.14 821 8168 0.1493 1.06 0.98,1.14 754 7567
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.7745 1.01 0.931,1.1 595 5901 0.6855 1.02 0.937,1.1 636 6413
251.1 Hypoglycemia endocrine/metabolic Both 0.8279 1.01 0.933,1.09 702 7015 0.6855 1.02 0.937,1.1 636 6413
252 Disorders of parathyroid gland endocrine/metabolic Both 0.5781 0.986 0.94,1.04 1807 17879 0.7379 0.982 0.88,1.09 362 3510
252.1 Hyperparathyroidism endocrine/metabolic Both 0.5984 0.987 0.938,1.04 1656 16459 0.7709 0.992 0.941,1.05 1517 14717
252.2 Hypoparathyroidism endocrine/metabolic Both 0.5998 0.972 0.876,1.08 393 3922 0.7379 0.982 0.88,1.09 362 3510
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.1622 1.06 0.978,1.14 691 6893 0.8414 1.02 0.815,1.29 84 866
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.6095 1.04 0.903,1.19 205 2041 0.03981 1.28 1.01,1.62 70 672
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.05888 1.25 0.992,1.58 72 720 0.03981 1.28 1.01,1.62 70 672
253.2 Pituitary hypofunction endocrine/metabolic Both 0.5152 1.05 0.905,1.22 184 1840 0.2786 1.09 0.934,1.27 177 1738
253.3 Diabetes insipidus endocrine/metabolic Both 0.984 1.0 0.795,1.26 70 694 0.8318 0.974 0.767,1.24 67 642
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.1117 1.2 0.959,1.5 92 899 0.1403 1.19 0.944,1.5 87 851
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.8241 1.02 0.828,1.27 93 925 0.8414 1.02 0.815,1.29 84 866
255 Disorders of adrenal glands endocrine/metabolic Both 0.00182 1.1 1.04,1.17 1186 11860 0.002818 1.16 1.05,1.28 420 4123
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.631 1.03 0.913,1.16 290 2886 0.7464 0.967 0.787,1.19 100 978
255.11 Cushing's syndrome endocrine/metabolic Both 0.1991 1.12 0.943,1.33 144 1440 0.25 1.11 0.929,1.33 133 1299
255.12 Hyperaldosteronism endocrine/metabolic Both 0.5309 0.939 0.77,1.14 106 1057 0.7464 0.967 0.787,1.19 100 978
255.2 Adrenal hypofunction endocrine/metabolic Both 0.01072 1.13 1.03,1.24 477 4758 0.002818 1.16 1.05,1.28 420 4123
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.009772 1.13 1.03,1.25 451 4496 0.002818 1.16 1.05,1.28 420 4123
256 Ovarian dysfunction endocrine/metabolic Female 0.09772 1.06 0.989,1.14 859 8184 0.6902 0.982 0.897,1.07 513 5033
256.4 Polycystic ovaries endocrine/metabolic Female 0.6998 0.983 0.9,1.07 544 5436 0.6902 0.982 0.897,1.07 513 5033
257 Testicular dysfunction endocrine/metabolic Male 0.5943 0.98 0.908,1.06 747 7455 0.5321 0.976 0.904,1.05 720 7212
257.1 Testicular hypofunction endocrine/metabolic Male 0.5129 0.975 0.902,1.05 725 7234 0.5321 0.976 0.904,1.05 720 7212
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.3758 1.11 0.877,1.42 66 660 0.06918 0.796 0.622,1.02 63 818
258.1 Postablative ovarian failure endocrine/metabolic Female 0.4018 1.09 0.891,1.33 92 920 0.06918 0.796 0.622,1.02 63 818
259 Other endocrine disorders endocrine/metabolic Both 0.2427 1.05 0.97,1.13 759 7562 0.4335 1.03 0.955,1.11 708 6880
260 Protein-calorie malnutrition endocrine/metabolic Both 0.4797 1.02 0.973,1.06 2353 22279 0.05623 1.09 0.998,1.18 608 6264
260.1 Cachexia endocrine/metabolic Both 0.9462 0.995 0.87,1.14 239 2388 0.9354 0.994 0.865,1.14 221 2266
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.5117 1.02 0.963,1.08 1363 13589 0.4406 0.96 0.866,1.06 398 3850
260.22 Nutritional marasmus endocrine/metabolic Both 0.3148 0.949 0.858,1.05 413 4130 0.4406 0.96 0.866,1.06 398 3850
260.3 Adult failure to thrive endocrine/metabolic Both 0.5047 1.03 0.942,1.13 509 5051 0.5309 1.03 0.937,1.13 469 4720
260.6 Anorexia endocrine/metabolic Both 0.03715 1.09 1.01,1.18 677 6722 0.05623 1.09 0.998,1.18 608 6264
261 Vitamin deficiency endocrine/metabolic Both 0.9683 0.999 0.971,1.03 5614 30157 0.8954 1.0 0.971,1.03 4703 27890
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.1774 0.946 0.873,1.03 649 6482 0.07943 0.926 0.851,1.01 588 5836
261.4 Vitamin D deficiency endocrine/metabolic Both 0.869 1.0 0.973,1.03 5264 29859 0.8954 1.0 0.971,1.03 4703 27890
262 Mineral deficiency NEC endocrine/metabolic Both 0.8913 0.995 0.928,1.07 854 8532 0.5689 1.02 0.949,1.1 783 7748
263 Other nutritional deficiency endocrine/metabolic Both 0.6714 1.02 0.922,1.13 412 4113 0.3177 1.06 0.948,1.18 367 3747
264 Lack of normal physiological development endocrine/metabolic Both 0.542 0.953 0.817,1.11 175 1735 0.6471 0.941 0.725,1.22 61 581
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.7362 1.04 0.843,1.27 95 950 0.7311 1.04 0.838,1.29 87 894
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.5058 0.915 0.704,1.19 61 607 0.6471 0.941 0.725,1.22 61 581
269 Proteinuria endocrine/metabolic Both 0.3767 1.03 0.966,1.09 1079 10768 0.2679 1.04 0.972,1.11 1004 10003
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.2037 1.05 0.974,1.13 740 7378 0.06026 1.14 0.994,1.31 205 2028
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.317 0.915 0.769,1.09 129 1283 0.6823 0.957 0.774,1.18 89 900
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.8892 0.986 0.807,1.2 101 998 0.6823 0.957 0.774,1.18 89 900
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.1042 1.2 0.963,1.5 81 810 0.06166 1.25 0.989,1.57 74 752
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.1905 1.06 0.971,1.16 560 5581 0.06026 1.14 0.994,1.31 205 2028
270.32 Paraproteinemia endocrine/metabolic Both 0.6792 1.03 0.911,1.15 301 2982 0.8017 1.02 0.897,1.15 272 2706
270.33 Amyloidosis endocrine/metabolic Both 0.3698 0.882 0.67,1.16 55 550 0.3133 0.864 0.65,1.15 51 515
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.07079 1.13 0.989,1.3 218 2178 0.06026 1.14 0.994,1.31 205 2028
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.02089 1.06 1.01,1.11 1952 19491 0.1416 1.2 0.942,1.52 74 753
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.03467 1.05 1.0,1.1 1885 18823 0.1253 1.04 0.989,1.09 1683 17197
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.06607 1.24 0.986,1.55 81 810 0.1416 1.2 0.942,1.52 74 753
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.1445 0.983 0.962,1.01 14793 22696 0.5598 0.96 0.836,1.1 218 2238
272.1 Hyperlipidemia endocrine/metabolic Both 0.1531 0.984 0.962,1.01 14763 22682 0.8204 1.01 0.96,1.05 2107 14278
272.11 Hypercholesterolemia endocrine/metabolic Both 0.8091 0.996 0.963,1.03 4668 18640 0.7691 0.995 0.961,1.03 4278 17164
272.12 Hyperglyceridemia endocrine/metabolic Both 0.8851 0.995 0.93,1.06 945 9395 0.6546 0.984 0.918,1.06 880 8737
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.7278 1.01 0.964,1.05 2272 15492 0.8204 1.01 0.96,1.05 2107 14278
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.6501 0.97 0.851,1.11 244 2425 0.5598 0.96 0.836,1.1 218 2238
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.7551 1.01 0.961,1.06 1971 18337 0.07413 0.842 0.698,1.02 123 1255
274.1 Gout endocrine/metabolic Both 0.5297 1.02 0.968,1.07 1879 17712 0.9397 0.997 0.926,1.07 755 7491
274.11 Gouty arthropathy endocrine/metabolic Both 0.826 1.01 0.938,1.08 793 7891 0.9397 0.997 0.926,1.07 755 7491
274.2 Crystal arthropathies endocrine/metabolic Both 0.1552 0.883 0.744,1.05 146 1425 0.07413 0.842 0.698,1.02 123 1255
274.21 Chondrocalcinosis endocrine/metabolic Both 0.1991 0.891 0.747,1.06 140 1363 0.07413 0.842 0.698,1.02 123 1255
275 Disorders of mineral metabolism endocrine/metabolic Both 0.8933 0.998 0.962,1.03 3252 30253 0.8299 0.973 0.756,1.25 65 646
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.6053 1.02 0.949,1.09 845 8441 0.4677 1.03 0.955,1.1 802 7803
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.7211 0.993 0.953,1.03 2502 24757 0.5834 1.02 0.954,1.09 966 9543
275.51 Hypocalcemia endocrine/metabolic Both 0.1679 1.06 0.978,1.14 722 7203 0.1603 1.06 0.978,1.15 659 6570
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.5117 1.02 0.959,1.09 1024 10193 0.5834 1.02 0.954,1.09 966 9543
275.6 Hypercalcemia endocrine/metabolic Both 0.861 0.994 0.933,1.06 1043 10415 0.8453 0.993 0.928,1.06 918 9299
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.1803 1.02 0.992,1.04 7227 30901 0.7925 1.03 0.825,1.29 85 913
276.1 Electrolyte imbalance endocrine/metabolic Both 0.1161 1.03 0.994,1.06 4833 28673 0.1409 1.04 0.987,1.1 1448 14717
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.2366 0.941 0.851,1.04 415 4115 0.2564 0.942 0.851,1.04 399 3871
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.06607 1.05 0.997,1.1 1857 17982 0.0955 1.04 0.993,1.1 1732 16764
276.13 Hyperpotassemia endocrine/metabolic Both 0.4375 1.02 0.974,1.06 2238 20576 0.414 1.02 0.974,1.07 2104 19169
276.14 Hypopotassemia endocrine/metabolic Both 0.09772 1.04 0.992,1.1 1626 16160 0.1409 1.04 0.987,1.1 1448 14717
276.4 Acid-base balance disorder endocrine/metabolic Both 0.1718 1.04 0.985,1.09 1593 15855 0.3846 1.05 0.938,1.18 326 3280
276.41 Acidosis endocrine/metabolic Both 0.1585 1.04 0.985,1.1 1357 13508 0.1178 1.05 0.989,1.11 1291 12634
276.42 Alkalosis endocrine/metabolic Both 0.8054 1.01 0.907,1.13 350 3498 0.3846 1.05 0.938,1.18 326 3280
276.5 Hypovolemia endocrine/metabolic Both 0.06457 1.03 0.998,1.07 3615 28901 0.05623 1.04 0.999,1.07 3276 26875
276.6 Fluid overload endocrine/metabolic Both 0.5023 1.02 0.959,1.09 1046 10404 0.3793 1.03 0.964,1.1 987 9731
276.8 Polydipsia endocrine/metabolic Both 0.7621 0.969 0.789,1.19 99 990 0.7925 1.03 0.825,1.29 85 913
277 Other disorders of metabolism endocrine/metabolic Both 0.787 1.01 0.956,1.06 1534 15324 0.9572 1.0 0.919,1.09 550 5529
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.4395 0.95 0.835,1.08 252 2520 0.3365 0.936 0.819,1.07 233 2371
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.8531 1.01 0.923,1.1 547 5456 0.5058 1.03 0.941,1.13 494 5187
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.3491 0.963 0.89,1.04 675 6743 0.4074 0.962 0.878,1.05 506 5189
277.51 Lipoprotein disorders endocrine/metabolic Both 0.5572 0.974 0.894,1.06 567 5665 0.4074 0.962 0.878,1.05 506 5189
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.6501 1.02 0.939,1.11 610 6090 0.9572 1.0 0.919,1.09 550 5529
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.4571 0.992 0.972,1.01 15130 23191 0.07762 0.95 0.897,1.01 1326 12312
278.1 Obesity endocrine/metabolic Both 0.6223 0.995 0.974,1.02 13507 23193 0.8318 1.0 0.975,1.03 5925 21579
278.11 Morbid obesity endocrine/metabolic Both 0.9908 1.0 0.973,1.03 6376 23143 0.8318 1.0 0.975,1.03 5925 21579
278.3 Localized adiposity endocrine/metabolic Both 0.03467 0.874 0.771,0.99 270 2694 0.07413 0.886 0.775,1.01 244 2391
278.4 Abnormal weight gain endocrine/metabolic Both 0.1828 0.965 0.915,1.02 1522 13685 0.07762 0.95 0.897,1.01 1326 12312
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.4345 1.02 0.974,1.06 2245 22393 0.9397 1.0 0.905,1.11 404 3909
279.1 Immunity deficiency endocrine/metabolic Both 0.618 1.02 0.95,1.09 881 8792 0.8222 1.02 0.89,1.16 243 2318
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.9954 1.0 0.88,1.14 254 2540 0.8222 1.02 0.89,1.16 243 2318
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.8091 0.989 0.908,1.08 574 5735 0.7261 1.02 0.928,1.11 522 5071
279.7 Other immunological findings endocrine/metabolic Both 0.1614 0.976 0.944,1.01 3927 30734 0.5585 0.99 0.956,1.02 3622 28440
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.867 0.992 0.899,1.09 443 4423 0.9397 1.0 0.905,1.11 404 3909
275.1 Disorders of iron metabolism hematopoietic Both 0.6166 1.04 0.89,1.22 168 1680 0.8299 0.973 0.756,1.25 65 646
275.11 Hereditary hemochromatosis hematopoietic Both 0.6792 0.95 0.744,1.21 70 700 0.8299 0.973 0.756,1.25 65 646
280 Iron deficiency anemias hematopoietic Both 0.6501 1.01 0.973,1.04 3537 25593 0.2307 1.04 0.978,1.1 1273 12438
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.7261 1.01 0.971,1.04 3410 25349 0.5117 1.01 0.975,1.05 3140 23578
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.4426 1.02 0.966,1.08 1361 13511 0.2307 1.04 0.978,1.1 1273 12438
281 Other deficiency anemia hematopoietic Both 0.1932 0.932 0.838,1.04 387 3838 0.6699 0.968 0.831,1.13 194 1962
281.1 Megaloblastic anemia hematopoietic Both 0.4775 0.947 0.815,1.1 189 1875 0.3062 0.905 0.746,1.1 118 1212
281.11 Pernicious anemia hematopoietic Both 0.04571 0.796 0.635,0.996 84 830 0.1119 0.819 0.641,1.05 71 731
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.08913 0.856 0.715,1.02 135 1348 0.3062 0.905 0.746,1.1 118 1212
281.9 Deficiency anemias hematopoietic Both 0.5728 0.96 0.832,1.11 214 2110 0.6699 0.968 0.831,1.13 194 1962
282 Hereditary hemolytic anemias hematopoietic Both 0.4446 0.951 0.835,1.08 248 2443 0.3673 0.923 0.777,1.1 131 1317
282.8 Other hemoglobinopathies hematopoietic Both 0.857 0.985 0.837,1.16 158 1541 0.8017 0.979 0.827,1.16 145 1419
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.3597 0.925 0.783,1.09 143 1420 0.3673 0.923 0.777,1.1 131 1317
283 Acquired hemolytic anemias hematopoietic Both 0.2028 0.892 0.748,1.06 130 1295 0.4989 0.939 0.782,1.13 121 1194
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.3811 0.884 0.67,1.17 54 532 ,
284 Aplastic anemia hematopoietic Both 0.4529 1.03 0.948,1.13 558 5545 0.6855 1.02 0.926,1.12 445 4556
284.1 Pancytopenia hematopoietic Both 0.5408 1.03 0.938,1.13 488 4847 0.6855 1.02 0.926,1.12 445 4556
285 Other anemias hematopoietic Both 0.5821 1.01 0.983,1.03 9426 28014 0.02188 1.12 1.02,1.24 420 5098
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.8147 0.995 0.955,1.04 2536 22457 0.8974 1.0 0.961,1.05 2418 20932
285.2 Anemia of chronic disease hematopoietic Both 0.16 1.04 0.985,1.09 1584 15823 0.02188 1.12 1.02,1.24 420 5098
285.21 Anemia in chronic kidney disease hematopoietic Both 0.7745 1.01 0.934,1.1 673 6722 0.6095 1.02 0.942,1.11 644 6274
285.22 Anemia in neoplastic disease hematopoietic Both 0.01318 1.12 1.02,1.22 555 5536 0.02188 1.12 1.02,1.24 420 5098
286 Coagulation defects hematopoietic Both 0.1045 0.969 0.933,1.01 3013 27144 0.02042 0.917 0.853,0.987 818 8090
286.1 Congenital coagulation defects hematopoietic Both 0.5346 0.954 0.821,1.11 190 1889 0.9931 0.999 0.803,1.24 88 899
286.11 Von willebrand's disease hematopoietic Both 0.4498 1.1 0.855,1.42 64 640 0.3327 1.14 0.872,1.5 59 575
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.6668 0.956 0.777,1.18 98 973 0.9931 0.999 0.803,1.24 88 899
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.1517 0.97 0.932,1.01 2601 20964 0.1832 0.972 0.931,1.01 2440 19459
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.8128 1.03 0.799,1.33 60 590 0.8851 0.981 0.757,1.27 58 560
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.08913 0.881 0.761,1.02 186 1860 0.1146 0.887 0.763,1.03 177 1737
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.1722 0.864 0.7,1.07 92 906 0.195 0.867 0.698,1.08 88 854
286.6 Defibrination syndrome hematopoietic Both 0.5129 0.985 0.94,1.03 1964 19522 0.597 0.987 0.941,1.04 1815 17962
286.7 Other and unspecified coagulation defects hematopoietic Both 0.4943 0.985 0.944,1.03 2349 23153 0.4819 0.984 0.942,1.03 2170 21348
286.8 Hypercoagulable state hematopoietic Both 0.1033 0.935 0.862,1.01 643 6420 0.2291 0.949 0.87,1.03 565 5655
286.81 Primary hypercoagulable state hematopoietic Both 0.2218 0.95 0.875,1.03 618 6179 0.2291 0.949 0.87,1.03 565 5655
286.9 Abnormal coagulation profile hematopoietic Both 0.02239 0.922 0.859,0.988 890 8770 0.02042 0.917 0.853,0.987 818 8090
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.6152 0.99 0.95,1.03 2575 22699 0.8995 1.02 0.794,1.3 72 713
287.1 Spontaneous ecchymoses hematopoietic Both 0.2239 0.906 0.772,1.06 154 1532 0.1371 0.879 0.741,1.04 136 1390
287.3 Thrombocytopenia hematopoietic Both 0.5943 0.988 0.946,1.03 2297 20909 0.7516 1.02 0.917,1.13 395 4086
287.31 Primary thrombocytopenia hematopoietic Both 0.4064 1.04 0.947,1.14 481 4785 0.5176 1.03 0.937,1.14 456 4456
287.32 Secondary thrombocytopenia hematopoietic Both 0.743 1.02 0.922,1.12 436 4360 0.7516 1.02 0.917,1.13 395 4086
287.4 Qualitative platelet defects hematopoietic Both 0.9268 1.01 0.796,1.29 76 760 0.8995 1.02 0.794,1.3 72 713
288 Diseases of white blood cells hematopoietic Both 0.0631 1.03 0.998,1.07 3850 30383 0.2679 1.11 0.923,1.33 122 1192
288.1 Decreased white blood cell count hematopoietic Both 0.1081 1.05 0.99,1.11 1252 12520 0.865 0.993 0.921,1.07 717 8329
288.11 Neutropenia hematopoietic Both 0.08913 1.06 0.991,1.14 896 8960 0.865 0.993 0.921,1.07 717 8329
288.2 Elevated white blood cell count hematopoietic Both 0.1038 1.03 0.994,1.07 3179 28632 0.1607 1.03 0.989,1.07 2953 26769
288.3 Eosinophilia hematopoietic Both 0.3112 1.1 0.918,1.31 128 1278 0.2679 1.11 0.923,1.33 122 1192
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.5047 1.02 0.963,1.08 1259 12554 0.9441 0.996 0.877,1.13 255 2555
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.7852 1.01 0.932,1.1 615 6123 0.7691 1.01 0.928,1.11 544 5604
289.4 Lymphadenitis hematopoietic Both 0.06166 1.04 0.998,1.07 3186 28420 0.2153 1.02 0.986,1.07 2807 26558
289.5 Diseases of spleen hematopoietic Both 0.1442 1.09 0.971,1.22 313 3130 0.3243 1.06 0.941,1.2 283 2957
289.8 Polycythemia, secondary hematopoietic Both 0.561 0.955 0.819,1.11 182 1820 0.7079 0.97 0.829,1.14 173 1757
289.9 Abnormality of red blood cells hematopoietic Both 0.9616 1.0 0.889,1.13 281 2776 0.9441 0.996 0.877,1.13 255 2555
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.8851 0.995 0.933,1.06 1040 9399 0.2649 1.05 0.964,1.14 583 5891
290.1 Dementias mental disorders Both 0.3899 0.956 0.861,1.06 407 3816 0.492 1.05 0.916,1.2 235 2192
290.11 Alzheimer's disease mental disorders Both 0.1294 0.855 0.699,1.05 104 984 0.3199 0.898 0.727,1.11 94 888
290.12 Dementia with cerebral degenerations mental disorders Both 0.8453 1.02 0.81,1.29 71 705 0.9441 1.01 0.787,1.29 63 645
290.13 Senile dementia mental disorders Both 0.6012 1.04 0.909,1.18 257 2376 0.492 1.05 0.916,1.2 235 2192
290.16 Vascular dementia mental disorders Both 0.9484 0.991 0.746,1.32 53 508 ,
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.873 1.01 0.928,1.09 634 6242 0.7295 1.01 0.934,1.1 601 5801
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.1936 1.06 0.973,1.14 642 6369 0.2649 1.05 0.964,1.14 583 5891
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.7311 0.992 0.947,1.04 1977 19673 0.2965 0.972 0.921,1.03 1444 14307
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.8933 1.01 0.863,1.18 161 1610 0.673 1.04 0.881,1.22 154 1512
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.8147 0.987 0.885,1.1 364 3634 0.8511 0.989 0.881,1.11 325 3359
291.8 Alteration of consciousness mental disorders Both 0.3273 0.974 0.925,1.03 1563 15497 0.2965 0.972 0.921,1.03 1444 14307
292 Neurological disorders mental disorders Both 0.1589 1.02 0.991,1.06 4340 31695 0.03981 1.19 1.01,1.42 136 1293
292.1 Aphasia/speech disturbance mental disorders Both 0.875 0.996 0.945,1.05 1554 15459 0.335 1.08 0.923,1.27 156 1522
292.11 Aphasia mental disorders Both 0.2838 1.05 0.96,1.15 516 5142 0.2075 1.06 0.967,1.17 469 4744
292.12 Symbolic dysfunction mental disorders Both 0.271 1.09 0.933,1.28 162 1620 0.335 1.08 0.923,1.27 156 1522
292.2 Mild cognitive impairment mental disorders Both 0.2198 1.08 0.954,1.23 276 2716 0.1033 1.11 0.978,1.27 251 2504
292.3 Memory loss mental disorders Both 0.2582 1.03 0.977,1.09 1405 13752 0.3373 1.03 0.971,1.09 1261 12616
292.4 Altered mental status mental disorders Both 0.4477 1.02 0.971,1.07 1885 18096 0.2472 1.03 0.98,1.08 1741 16766
292.5 Transient alteration of awareness mental disorders Both 0.2606 1.07 0.953,1.19 327 3237 0.1618 1.09 0.967,1.22 304 2982
292.6 Hallucinations mental disorders Both 0.05888 1.17 0.994,1.38 144 1429 0.03981 1.19 1.01,1.42 136 1293
293 Symptoms involving head and neck mental disorders Both 0.8204 0.986 0.875,1.11 304 3036 0.1479 0.974 0.94,1.01 3381 30082
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.2825 0.981 0.949,1.02 3691 32427 0.1479 0.974 0.94,1.01 3381 30082
295 Schizophrenia and other psychotic disorders mental disorders Both 0.9376 1.0 0.927,1.09 664 6564 0.5794 1.03 0.935,1.13 468 4824
295.1 Schizophrenia mental disorders Both 0.5623 1.06 0.878,1.27 111 1080 0.4932 1.07 0.882,1.3 100 1010
295.2 Paranoid disorders mental disorders Both 0.8472 0.979 0.791,1.21 86 856 0.7295 0.962 0.771,1.2 78 794
295.3 Psychosis mental disorders Both 0.6592 1.02 0.934,1.11 527 5206 0.5794 1.03 0.935,1.13 468 4824
296 Mood disorders mental disorders Both 0.7834 1.0 0.98,1.03 12028 17942 0.9099 0.999 0.974,1.02 9772 16930
296.1 Bipolar mental disorders Both 0.7962 1.01 0.945,1.08 994 9331 0.8204 1.01 0.942,1.08 914 8654
296.2 Depression mental disorders Both 0.8453 1.0 0.979,1.03 11641 17941 0.9099 0.999 0.974,1.02 9772 16930
296.22 Major depressive disorder mental disorders Both 0.8892 1.0 0.978,1.03 10773 17942 0.9099 0.999 0.974,1.02 9772 16930
297 Suicidal ideation or attempt mental disorders Both 0.9528 1.0 0.927,1.08 696 6932 0.7586 1.02 0.885,1.18 188 1890
297.1 Suicidal ideation mental disorders Both 0.9727 0.998 0.916,1.09 559 5575 0.8995 0.994 0.91,1.09 526 5250
297.2 Suicide or self-inflicted injury mental disorders Both 0.8492 1.01 0.881,1.17 201 2010 0.7586 1.02 0.885,1.18 188 1890
300 Anxiety disorders mental disorders Both 0.8933 1.0 0.978,1.03 12038 17949 0.2051 1.06 0.971,1.15 579 5688
300.1 Anxiety disorder mental disorders Both 0.7621 1.0 0.98,1.03 11352 17942 3.89E-4 0.866 0.8,0.938 658 6703
300.11 Generalized anxiety disorder mental disorders Both 0.7656 0.995 0.962,1.03 4496 17788 0.2355 0.979 0.945,1.01 3974 16776
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.06761 0.94 0.88,1.0 957 9152 0.07943 0.94 0.878,1.01 880 8441
300.13 Phobia mental disorders Both 0.00195 0.888 0.823,0.957 731 7231 3.89E-4 0.866 0.8,0.938 658 6703
300.3 Obsessive-compulsive disorders mental disorders Both 0.5572 0.96 0.839,1.1 223 2230 0.6592 0.969 0.844,1.11 210 2059
300.4 Dysthymic disorder mental disorders Both 0.1033 1.04 0.992,1.09 1798 13630 0.7129 1.01 0.959,1.06 1610 12640
300.8 Acute reaction to stress mental disorders Both 0.342 0.949 0.853,1.06 359 3536 0.3733 0.949 0.845,1.07 310 3210
300.9 Posttraumatic stress disorder mental disorders Both 0.2979 1.04 0.962,1.13 612 6113 0.2051 1.06 0.971,1.15 579 5688
301 Personality disorders mental disorders Both 0.618 1.03 0.924,1.14 363 3626 0.1585 1.11 0.959,1.29 180 1731
301.2 Antisocial/borderline personality disorder mental disorders Both 0.1452 1.11 0.963,1.29 187 1868 0.1585 1.11 0.959,1.29 180 1731
302 Sexual and gender identity disorders mental disorders Both 0.4406 1.03 0.951,1.12 608 6055 0.8492 1.01 0.898,1.14 293 3032
302.1 Decreased libido mental disorders Both 0.6252 1.03 0.918,1.15 325 3233 0.8492 1.01 0.898,1.14 293 3032
303 Psychogenic and somatoform disorders mental disorders Both 0.02291 0.929 0.871,0.99 1030 10064 0.03631 0.929 0.867,0.995 868 8375
303.1 Dissociative disorder mental disorders Both 0.8974 0.988 0.819,1.19 115 1144 0.8166 0.978 0.807,1.18 107 1054
303.3 Psychogenic disorder mental disorders Both 0.0631 0.931 0.864,1.0 736 7330 0.02754 0.88 0.786,0.986 316 3100
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.0257 0.883 0.791,0.985 340 3376 0.02754 0.88 0.786,0.986 316 3100
303.4 Somatoform disorder mental disorders Both 0.01778 0.922 0.862,0.986 925 9106 0.03631 0.929 0.867,0.995 868 8375
304 Adjustment reaction mental disorders Both 0.8872 1.0 0.964,1.04 2840 17464 0.3565 0.98 0.94,1.02 2530 16454
305.2 Eating disorder mental disorders Both 0.5093 1.03 0.949,1.11 650 6500 0.8453 1.01 0.927,1.1 581 5914
306 Other mental disorder mental disorders Both 0.7816 0.992 0.936,1.05 1254 10907 0.3296 0.954 0.869,1.05 460 4764
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.3141 1.05 0.952,1.17 418 2847 0.3483 1.05 0.947,1.17 397 2665
306.9 Tension headache mental disorders Both 0.3733 0.961 0.879,1.05 521 5210 0.3296 0.954 0.869,1.05 460 4764
312 Conduct disorders mental disorders Both 0.6039 1.04 0.896,1.21 189 1890 0.7656 1.02 0.879,1.19 179 1783
312.3 Impulse control disorder mental disorders Both 0.2612 1.17 0.892,1.53 53 530 ,
313 Pervasive developmental disorders mental disorders Both 0.7925 0.992 0.934,1.05 1148 11078 0.5445 1.09 0.832,1.42 58 553
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.4581 0.976 0.915,1.04 1012 9899 0.4539 0.975 0.913,1.04 956 9424
313.2 Tics and stuttering mental disorders Both 0.5395 1.08 0.837,1.4 60 593 0.5445 1.09 0.832,1.42 58 553
315 Develomental delays and disorders mental disorders Both 0.6531 1.02 0.925,1.13 401 3990 0.4898 1.05 0.907,1.23 171 1655
315.1 Learning disorder mental disorders Both 0.3273 1.14 0.876,1.49 60 599 0.4055 1.12 0.857,1.46 58 569
315.2 Speech and language disorder mental disorders Both 0.6138 1.04 0.897,1.2 182 1801 0.4898 1.05 0.907,1.23 171 1655
316 Substance addiction and disorders mental disorders Both 0.01349 1.05 1.01,1.09 2799 26014 0.9863 1.0 0.889,1.13 293 4645
316.1 Polyneuropathy due to drugs mental disorders Both 0.07244 1.09 0.992,1.19 518 5180 0.9863 1.0 0.889,1.13 293 4645
317 Alcohol-related disorders mental disorders Both 0.1754 1.03 0.986,1.08 1948 17547 0.04266 1.12 1.0,1.26 324 3170
317.1 Alcoholism mental disorders Both 0.07244 1.05 0.996,1.11 1517 14733 0.04266 1.12 1.0,1.26 324 3170
317.11 Alcoholic liver damage mental disorders Both 0.1274 1.09 0.976,1.22 335 3336 0.04266 1.12 1.0,1.26 324 3170
318 Tobacco use disorder mental disorders Both 0.4977 1.01 0.985,1.03 9473 26924 0.309 1.01 0.988,1.04 8958 24995
320 Meningitis neurological Both 0.1545 1.09 0.969,1.22 319 3181 0.08913 1.11 0.984,1.25 288 2929
323 Encephalitis neurological Both 0.787 1.02 0.864,1.21 148 1475 0.8147 1.02 0.844,1.24 118 1152
323.8 Encephalitis, non-infectious neurological Both 0.811 1.02 0.85,1.23 125 1245 0.8147 1.02 0.844,1.24 118 1152
324 Other CNS infection and poliomyelitis neurological Both 0.3741 1.06 0.931,1.21 245 2440 0.25 1.08 0.946,1.24 234 2262
327 Sleep disorders neurological Both 0.857 1.0 0.98,1.02 11517 26652 0.7464 0.99 0.931,1.05 1118 10931
327.1 Hypersomnia neurological Both 0.4808 1.02 0.965,1.08 1403 13919 0.5176 1.02 0.962,1.08 1292 12786
327.3 Sleep apnea neurological Both 0.4365 0.99 0.966,1.02 8293 26193 0.3327 0.986 0.959,1.01 6156 23730
327.31 Central/nonobstroctive sleep apnea neurological Both 0.4932 1.04 0.929,1.16 326 3234 0.5023 1.04 0.927,1.17 310 3025
327.32 Obstructive sleep apnea neurological Both 0.2904 0.985 0.959,1.01 6534 25537 0.3327 0.986 0.959,1.01 6156 23730
327.4 Insomnia neurological Both 0.3027 1.02 0.985,1.05 4197 25860 0.3664 1.03 0.961,1.11 762 7975
327.41 Organic or persistent insomnia neurological Both 0.06026 1.07 0.997,1.15 881 8743 0.3664 1.03 0.961,1.11 762 7975
327.5 Parasomnia neurological Both 0.3648 0.956 0.868,1.05 459 4583 0.5636 0.971 0.877,1.07 422 4245
327.6 Circadian rhythm sleep disorder neurological Both 0.8492 1.02 0.869,1.19 174 1738 0.9683 0.997 0.849,1.17 160 1589
327.7 Sleep related movement disorders neurological Both 0.4027 0.977 0.924,1.03 1364 13620 0.7464 0.99 0.931,1.05 1118 10931
327.71 Restless legs syndrome neurological Both 0.3334 0.971 0.916,1.03 1214 12132 0.7464 0.99 0.931,1.05 1118 10931
327.72 Sleep related leg cramps neurological Both 0.1483 1.21 0.934,1.57 55 550 ,
331 Other cerebral degenerations neurological Both 0.492 0.971 0.893,1.06 602 5935 0.5715 1.03 0.922,1.16 323 3161
331.1 Hydrocephalus neurological Both 0.1194 0.903 0.795,1.03 246 2447 0.4375 0.949 0.832,1.08 228 2267
331.9 Cerebral degeneration, unspecified neurological Both 0.5321 1.04 0.928,1.16 349 3423 0.5715 1.03 0.922,1.16 323 3161
332 Parkinson's disease neurological Both 0.4178 1.05 0.936,1.17 333 3321 0.4335 1.05 0.933,1.17 316 3071
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.5702 0.987 0.945,1.03 2169 20920 0.1227 1.23 0.945,1.61 57 596
333.1 Essential tremor neurological Both 0.863 1.01 0.923,1.1 551 5488 0.8913 1.01 0.918,1.1 500 5037
333.2 Myoclonus neurological Both 0.7745 1.03 0.853,1.24 117 1160 0.5082 1.07 0.879,1.3 108 1047
333.4 Torsion dystonia neurological Both 0.1644 1.09 0.965,1.24 266 2646 0.07762 1.12 0.987,1.28 243 2358
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.08913 1.24 0.967,1.6 64 640 0.1227 1.23 0.945,1.61 57 596
334 Degenerative disease of the spinal cord neurological Both 0.8954 1.0 0.937,1.08 874 8734 0.879 1.02 0.772,1.35 52 532
334.1 Spinocerebellar disease neurological Both 0.414 0.901 0.702,1.16 64 631 0.7261 0.955 0.739,1.23 60 567
334.2 Anterior horn cell disease neurological Both 0.302 1.12 0.903,1.39 92 920 0.879 1.02 0.772,1.35 52 532
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.929 0.988 0.756,1.29 57 570 0.879 1.02 0.772,1.35 52 532
335 Multiple sclerosis neurological Both 0.01148 0.866 0.774,0.968 330 3284 0.02399 0.874 0.778,0.983 307 2927
337 Disorders of the autonomic nervous system neurological Both 0.597 1.02 0.937,1.12 528 5257 0.2208 1.1 0.944,1.28 172 1698
337.1 Peripheral autonomic neuropathy neurological Both 0.3162 1.08 0.93,1.25 185 1837 0.2208 1.1 0.944,1.28 172 1698
338 Pain neurological Both 0.7031 1.0 0.984,1.02 16189 22165 0.3199 1.01 0.987,1.04 7590 20686
338.1 Acute pain neurological Both 0.6109 1.01 0.984,1.03 12567 22166 0.5702 1.01 0.984,1.03 11621 20697
338.2 Chronic pain neurological Both 0.4842 1.01 0.984,1.04 8223 22154 0.3199 1.01 0.987,1.04 7590 20686
339 Other headache syndromes neurological Both 0.6531 0.994 0.97,1.02 8578 27793 0.877 0.998 0.972,1.02 7847 25986
340 Migraine neurological Both 0.4677 0.989 0.959,1.02 5377 24263 0.2685 1.02 0.982,1.07 2611 16908
340.1 Migrain with aura neurological Both 0.4385 1.02 0.976,1.06 2862 18665 0.2685 1.02 0.982,1.07 2611 16908
341 Other demyelinating diseases of central nervous system neurological Both 0.695 0.962 0.793,1.17 111 1105 0.6592 0.957 0.789,1.16 109 1016
342 Hemiplegia neurological Both 0.7709 1.02 0.913,1.13 360 3589 0.5188 1.04 0.929,1.16 336 3330
343 Infantile cerebral palsy neurological Both 0.984 0.998 0.792,1.26 75 750 0.9397 0.991 0.78,1.26 71 694
344 Other paralytic syndromes neurological Both 0.4093 1.04 0.951,1.13 564 5640 0.2735 1.05 0.962,1.15 535 5223
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.4977 1.02 0.971,1.06 2084 20790 0.08318 1.04 0.994,1.09 1836 18212
345.1 Epilepsy neurological Both 0.2291 1.05 0.968,1.14 607 6053 0.4416 1.04 0.939,1.16 401 4044
345.11 Generalized convulsive epilepsy neurological Both 0.118 1.12 0.971,1.29 196 1960 0.09772 1.13 0.977,1.31 188 1848
345.12 Partial epilepsy neurological Both 0.6998 1.02 0.923,1.13 434 4333 0.4416 1.04 0.939,1.16 401 4044
345.3 Convulsions neurological Both 0.3597 1.02 0.976,1.07 1967 19598 0.08318 1.04 0.994,1.09 1836 18212
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.8851 0.988 0.832,1.17 142 1404 0.6209 1.06 0.851,1.31 82 809
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.6138 1.02 0.957,1.08 1196 11927 0.271 1.04 0.973,1.1 1090 10898
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.811 0.974 0.783,1.21 87 860 0.3365 0.893 0.709,1.13 77 812
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.8337 1.02 0.831,1.26 90 884 0.6209 1.06 0.851,1.31 82 809
347 Cataplexy and narcolepsy neurological Both 0.3811 1.12 0.874,1.42 67 670 0.3342 1.13 0.88,1.46 62 615
348 Other conditions of brain neurological Both 0.5598 1.02 0.962,1.07 1424 14226 0.5794 1.01 0.966,1.06 1852 18478
348.2 Cerebral edema and compression of brain neurological Both 0.5781 0.979 0.908,1.06 747 7463 0.984 0.999 0.924,1.08 679 6953
348.4 Cerebral cysts neurological Both 0.6266 0.964 0.832,1.12 195 1945 0.5383 0.952 0.815,1.11 173 1786
348.7 Coma neurological Both 0.00263 1.28 1.09,1.5 162 1620 0.00195 1.3 1.1,1.53 153 1504
348.8 Encephalopathy, not elsewhere classified neurological Both 0.2649 1.05 0.965,1.14 636 6331 0.2203 1.05 0.969,1.15 590 5819
348.9 Other conditions of brain, NOS neurological Both 0.9683 1.0 0.956,1.05 2001 19979 0.5794 1.01 0.966,1.06 1852 18478
349 Other and unspecified disorders of the nervous system neurological Both 0.01 0.908 0.843,0.977 775 7750 0.03715 0.923 0.856,0.995 738 7079
350 Abnormal movement neurological Both 0.4217 1.01 0.983,1.04 5109 32314 0.4753 0.964 0.873,1.07 413 4187
350.1 Abnormal involuntary movements neurological Both 0.4198 1.02 0.976,1.06 2464 24243 0.6081 1.01 0.968,1.06 2237 22387
350.2 Abnormality of gait neurological Both 0.4775 1.01 0.976,1.05 2979 25007 0.3228 1.02 0.981,1.06 2726 23099
350.3 Lack of coordination neurological Both 0.9705 1.0 0.93,1.08 773 7693 0.857 1.01 0.932,1.09 708 7035
350.5 Abnormal reflex neurological Both 0.3972 0.928 0.781,1.1 143 1430 0.6808 0.963 0.804,1.15 130 1283
350.6 Disturbances of sensation of smell and taste neurological Both 0.3055 0.951 0.863,1.05 448 4480 0.4753 0.964 0.873,1.07 413 4187
351 Other peripheral nerve disorders neurological Both 0.05888 0.973 0.945,1.0 5685 28844 0.06026 0.972 0.943,1.0 5177 26856
352 Disorders of other cranial nerves neurological Both 0.006607 0.927 0.878,0.979 1412 14120 0.02188 0.906 0.833,0.986 591 5861
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.9863 1.0 0.907,1.1 440 4393 0.9954 1.0 0.901,1.11 399 3957
352.2 Facial nerve disorders [CN7] neurological Both 0.04169 0.919 0.848,0.997 640 6400 0.02188 0.906 0.833,0.986 591 5861
353 Nerve root and plexus disorders neurological Both 0.4842 0.987 0.952,1.02 3295 28097 0.15 1.17 0.945,1.44 89 848
353.1 Nerve plexus lesions neurological Both 0.6067 0.969 0.861,1.09 308 3077 0.673 0.974 0.861,1.1 285 2884
353.2 Nerve root lesions neurological Both 0.1986 1.14 0.932,1.41 94 930 0.15 1.17 0.945,1.44 89 848
355 Complex regional/central pain syndrome neurological Both 0.4909 0.965 0.873,1.07 419 4170 0.9141 1.0 0.923,1.09 605 5922
355.1 Chronic pain syndrome neurological Both 0.8974 1.01 0.927,1.09 654 6509 0.9141 1.0 0.923,1.09 605 5922
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.4111 0.979 0.932,1.03 1728 17176 0.4721 0.981 0.931,1.03 1562 15899
357 Inflammatory and toxic neuropathy neurological Both 0.912 1.0 0.962,1.04 2467 24091 0.9397 0.998 0.955,1.04 2180 22261
358 Myoneural disorders neurological Both 0.9594 1.0 0.934,1.07 845 8441 0.3565 0.898 0.714,1.13 80 787
358.1 Myasthenia gravis neurological Both 0.3758 0.904 0.723,1.13 85 850 0.3565 0.898 0.714,1.13 80 787
359 Muscular dystrophies and other myopathies neurological Both 0.2735 0.962 0.897,1.03 868 8655 0.3055 0.962 0.893,1.04 762 7584
359.1 Muscular dystrophies neurological Both 0.6982 1.06 0.802,1.39 52 520 ,
359.2 Myopathy neurological Both 0.207 0.955 0.889,1.03 833 8306 0.3055 0.962 0.893,1.04 762 7584
360 Disorders of the globe sense organs Both 0.6223 0.95 0.776,1.16 102 1013 0.9506 1.01 0.818,1.24 95 943
361 Retinal detachments and defects sense organs Both 0.007079 1.13 1.03,1.24 528 5265 0.1995 1.1 0.952,1.26 203 2059
361.1 Retinal detachment with retinal defect sense organs Both 0.1047 1.12 0.977,1.28 225 2226 0.1995 1.1 0.952,1.26 203 2059
362 Other retinal disorders sense organs Both 0.5623 1.01 0.971,1.06 2489 18838 0.2897 1.09 0.933,1.26 183 1840
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.2014 1.04 0.982,1.09 1529 12328 0.7586 0.99 0.932,1.05 1173 9996
362.21 Macular degeneration, dry sense organs Both 0.9908 0.999 0.887,1.13 313 2650 0.4335 0.951 0.839,1.08 281 2411
362.22 Macular degeneration, wet sense organs Both 0.6109 1.05 0.862,1.29 108 881 0.9705 1.0 0.805,1.25 88 801
362.23 Cystoid macular degeneration of retina sense organs Both 0.06166 1.13 0.994,1.28 285 2777 0.2449 1.08 0.948,1.23 251 2547
362.26 Macular puckering of retina sense organs Both 0.2382 1.05 0.968,1.14 645 6254 0.9462 1.0 0.92,1.09 570 5743
362.27 Drusen (degenerative) of retina sense organs Both 0.5 1.04 0.929,1.16 335 3205 0.7482 1.02 0.905,1.15 299 2879
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.2606 1.03 0.976,1.09 1323 10928 0.7586 0.99 0.932,1.05 1173 9996
362.3 Other nondiabetic retinopathy sense organs Both 0.3673 1.04 0.957,1.13 653 6476 0.4932 1.04 0.922,1.18 272 2749
362.31 Separation of retinal layers sense organs Both 0.2938 1.07 0.946,1.2 296 2938 0.4932 1.04 0.922,1.18 272 2749
362.4 Retinal vascular changes and abnomalities sense organs Both 0.5058 0.968 0.878,1.07 449 4295 0.3499 0.952 0.859,1.06 403 3950
362.6 Peripheral retinal degenerations sense organs Both 0.6152 0.969 0.855,1.1 262 2600 0.309 0.933 0.817,1.07 234 2371
362.7 Hereditary retinal dystrophies sense organs Both 0.5821 1.05 0.873,1.27 124 1233 0.8995 1.01 0.827,1.24 107 1117
362.8 Retinal hemorrhage/ischemia sense organs Both 0.9183 1.01 0.855,1.19 160 1570 0.7798 1.02 0.865,1.21 150 1451
362.9 Retinal edema sense organs Both 0.3516 1.07 0.928,1.23 202 2001 0.2897 1.09 0.933,1.26 183 1840
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.105 1.09 0.982,1.21 375 3665 0.7568 1.02 0.892,1.17 230 2231
363.3 Chorioretinal scars sense organs Both 0.3055 1.07 0.94,1.22 249 2430 0.7568 1.02 0.892,1.17 230 2231
364 Corneal opacity and other disorders of cornea sense organs Both 0.9441 1.0 0.933,1.08 809 7919 0.5035 1.09 0.847,1.4 65 618
364.1 Corneal opacity sense organs Both 0.3733 1.05 0.938,1.19 294 2930 0.2203 1.08 0.955,1.22 270 2676
364.2 Corneal edema sense organs Both 0.6622 0.951 0.76,1.19 84 819 0.514 0.924 0.73,1.17 74 746
364.4 Corneal degenerations sense organs Both 0.3133 1.06 0.942,1.2 274 2719 0.3177 1.07 0.939,1.22 246 2459
364.5 Corneal dystrophy sense organs Both 0.2805 1.06 0.953,1.18 377 3673 0.4217 0.94 0.81,1.09 180 1797
364.51 Fuchs' dystrophy sense organs Both 0.5572 0.959 0.833,1.1 207 2008 0.4217 0.94 0.81,1.09 180 1797
364.9 Cornea replaced by transplant sense organs Both 0.5176 1.08 0.848,1.39 69 677 0.5035 1.09 0.847,1.4 65 618
365 Glaucoma sense organs Both 0.9016 0.997 0.952,1.04 1986 17152 0.597 0.959 0.821,1.12 167 1548
365.1 Open-angle glaucoma sense organs Both 0.881 1.01 0.919,1.1 523 4963 0.6823 0.973 0.854,1.11 252 2398
365.11 Primary open angle glaucoma sense organs Both 0.8204 1.01 0.897,1.15 281 2609 0.6823 0.973 0.854,1.11 252 2398
365.2 Primary angle-closure glaucoma sense organs Both 0.6561 0.966 0.832,1.12 179 1707 0.597 0.959 0.821,1.12 167 1548
366 Cataract sense organs Both 0.8492 0.997 0.968,1.03 6335 23476 0.4385 1.01 0.978,1.05 3382 18844
366.1 Nonsenile Cataract sense organs Both 0.1153 1.14 0.969,1.33 163 1622 0.04074 1.19 1.01,1.42 141 1484
366.2 Senile cataract sense organs Both 0.2541 1.02 0.985,1.06 3827 20410 0.4385 1.01 0.978,1.05 3382 18844
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.7295 1.0 0.978,1.03 6553 31745 0.123 0.947 0.884,1.01 902 8915
367.1 Myopia sense organs Both 0.7015 0.993 0.959,1.03 3578 28818 0.3639 0.983 0.948,1.02 3207 26782
367.2 Astigmatism sense organs Both 0.2028 1.03 0.987,1.07 2892 26106 0.492 1.01 0.974,1.06 2612 24130
367.4 Presbyopia sense organs Both 0.06457 1.04 0.998,1.07 3297 24582 0.2018 1.03 0.987,1.07 2900 22640
367.8 Hypermetropia sense organs Both 0.4688 1.02 0.967,1.08 1504 14729 0.9247 1.0 0.948,1.06 1338 13375
367.9 Blindness and low vision sense organs Both 0.1758 0.955 0.894,1.02 976 9663 0.123 0.947 0.884,1.01 902 8915
368 Visual disturbances sense organs Both 0.4667 0.988 0.957,1.02 4287 32818 0.6223 1.06 0.844,1.33 79 810
368.1 Amblyopia sense organs Both 0.7674 0.986 0.896,1.08 484 4830 0.5224 0.968 0.876,1.07 448 4436
368.2 Diplopia and disorders of binocular vision sense organs Both 0.04169 1.08 1.0,1.16 822 8186 0.008318 1.11 1.03,1.19 759 7554
368.3 Anisometropia sense organs Both 0.861 0.986 0.841,1.16 166 1648 0.6998 0.968 0.819,1.14 151 1522
368.4 Visual field defects sense organs Both 0.5284 0.978 0.913,1.05 879 8777 0.526 0.977 0.908,1.05 795 8009
368.9 Subjective visual disturbances sense organs Both 0.6808 0.985 0.918,1.06 829 8268 0.6223 1.06 0.844,1.33 79 810
368.91 Psychophysical visual disturbances sense organs Both 0.3707 1.1 0.89,1.37 89 885 0.6223 1.06 0.844,1.33 79 810
369 Infection of the eye sense organs Both 0.9376 1.0 0.96,1.05 2328 22262 0.4018 0.979 0.933,1.03 1761 17737
369.2 Eye infection, viral sense organs Both 0.6887 0.978 0.879,1.09 372 3688 0.877 0.991 0.886,1.11 333 3364
369.5 Conjunctivitis, infectious sense organs Both 0.7798 0.993 0.949,1.04 1974 19408 0.4018 0.979 0.933,1.03 1761 17737
370 Keratitis sense organs Both 0.9376 1.0 0.941,1.07 1051 10280 0.5212 1.06 0.883,1.28 122 1243
370.1 Corneal ulcer sense organs Both 0.4656 0.943 0.805,1.1 164 1630 0.5188 0.947 0.801,1.12 148 1497
370.2 Superficial keratitis sense organs Both 0.7603 0.984 0.888,1.09 394 3916 0.8395 0.989 0.887,1.1 347 3545
370.3 Keratoconjunctivitis sense organs Both 0.9376 0.996 0.911,1.09 531 5159 0.5212 1.06 0.883,1.28 122 1243
370.31 Keratoconjunctivitis sicca sense organs Both 0.2042 1.11 0.944,1.31 150 1432 0.5212 1.06 0.883,1.28 122 1243
371 Inflammation of the eye sense organs Both 0.7031 0.993 0.957,1.03 3269 26161 0.8954 0.986 0.795,1.22 91 878
371.1 Uveitis, noninfectious or NOS sense organs Both 0.4426 0.96 0.865,1.07 394 3892 0.6637 0.976 0.875,1.09 355 3575
371.2 Conjunctivitis, noninfectious sense organs Both 0.5794 0.978 0.903,1.06 651 6462 0.2723 0.949 0.864,1.04 472 4729
371.21 Allergic conjunctivitis sense organs Both 0.4027 0.963 0.882,1.05 532 5279 0.2723 0.949 0.864,1.04 472 4729
371.3 Inflammation of eyelids sense organs Both 0.7834 0.994 0.954,1.04 2523 21781 0.8954 0.986 0.795,1.22 91 878
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.9705 1.0 0.819,1.23 100 979 0.8954 0.986 0.795,1.22 91 878
372 Disorders of conjunctiva sense organs Both 0.2163 0.956 0.89,1.03 827 8153 0.4645 0.972 0.901,1.05 743 7484
374 Other disorders of eyelids sense organs Both 0.8892 0.997 0.953,1.04 2093 18512 0.1081 0.936 0.864,1.01 658 6679
374.1 Ectropion or entropion sense organs Both 0.5848 0.969 0.866,1.08 337 3251 0.631 0.972 0.865,1.09 309 3011
374.2 Lagophthalmos sense organs Both 0.1422 0.896 0.773,1.04 192 1900 0.1675 0.898 0.77,1.05 176 1762
374.3 Ptosis of eyelid sense organs Both 0.4111 0.97 0.903,1.04 817 8140 0.2371 0.955 0.885,1.03 722 7367
374.6 Dermatochalasis sense organs Both 0.3055 0.962 0.892,1.04 759 7426 0.1081 0.936 0.864,1.01 658 6679
375 Disorders of lacrimal system sense organs Both 0.9594 1.0 0.961,1.04 2683 21054 0.7499 1.02 0.906,1.15 298 3214
375.1 Dry eyes sense organs Both 0.342 1.02 0.98,1.06 2966 21823 0.5521 1.01 0.972,1.06 2568 19935
375.2 Epiphora sense organs Both 0.6124 1.03 0.923,1.15 356 3540 0.7499 1.02 0.906,1.15 298 3214
376 Disorders of the orbit sense organs Both 0.5 0.959 0.85,1.08 285 2814 0.2917 0.935 0.825,1.06 265 2612
377 Disorders of optic nerve and visual pathways sense organs Both 0.01 0.902 0.834,0.976 706 7010 0.03802 0.9 0.814,0.994 431 4285
377.1 Optic atrophy sense organs Both 0.9376 0.994 0.858,1.15 200 1997 0.4592 0.942 0.805,1.1 174 1866
377.3 Optic neuritis/neuropathy sense organs Both 0.005248 0.872 0.792,0.96 468 4627 0.03802 0.9 0.814,0.994 431 4285
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.6902 0.987 0.924,1.05 969 9602 0.5781 0.965 0.85,1.09 256 2520
378.1 Strabismus (not specified as paralytic) sense organs Both 0.4305 1.03 0.951,1.12 617 6131 0.4508 1.03 0.948,1.13 564 5660
378.2 Nystagmus and other irregular eye movements sense organs Both 0.8072 0.978 0.82,1.17 138 1371 0.9141 1.01 0.843,1.21 131 1277
378.5 Paralytic strabismus sense organs Both 0.3027 0.937 0.829,1.06 275 2720 0.5781 0.965 0.85,1.09 256 2520
379 Other disorders of eye sense organs Both 0.6457 1.01 0.973,1.04 3593 24835 0.1507 0.947 0.88,1.02 789 7835
379.1 Scleritis and episcleritis sense organs Both 0.6442 0.961 0.81,1.14 140 1379 0.4842 0.939 0.787,1.12 130 1234
379.2 Disorders of vitreous body sense organs Both 0.236 1.03 0.984,1.07 2559 18709 0.5821 1.01 0.969,1.06 2245 17201
379.3 Aphakia and other disorders of lens sense organs Both 0.6295 0.948 0.762,1.18 87 838 0.2825 0.879 0.694,1.11 77 792
379.4 Anomalies of pupillary function sense organs Both 0.5559 0.96 0.84,1.1 231 2303 0.8204 0.984 0.855,1.13 211 2133
379.5 Disorders of iris and ciliary body sense organs Both 0.4571 1.05 0.917,1.21 215 2128 0.5916 0.926 0.7,1.23 54 566
379.51 Pigmentary iris degeneration sense organs Both 0.7586 0.96 0.737,1.25 61 610 0.5916 0.926 0.7,1.23 54 566
379.9 Pain, swelling or discharge of eye sense organs Both 0.1393 0.948 0.884,1.02 870 8594 0.1507 0.947 0.88,1.02 789 7835
380 Disorders of external ear sense organs Both 0.4121 0.979 0.93,1.03 1634 15553 0.8054 1.01 0.958,1.06 1790 17192
380.1 Otitis externa sense organs Both 0.514 0.98 0.922,1.04 1124 11213 0.5848 0.983 0.922,1.05 1032 10394
380.4 Impacted cerumen sense organs Both 0.4634 1.02 0.972,1.07 1985 18630 0.8054 1.01 0.958,1.06 1790 17192
381 Otitis media and Eustachian tube disorders sense organs Both 0.3184 0.982 0.947,1.02 3291 29339 0.7674 0.982 0.87,1.11 282 2727
381.1 Otitis media sense organs Both 0.9333 0.998 0.957,1.04 2402 23549 0.9506 0.999 0.953,1.05 1894 18643
381.11 Suppurative and unspecified otitis media sense organs Both 0.867 0.996 0.952,1.04 2037 20175 0.9506 0.999 0.953,1.05 1894 18643
381.2 Eustachian tube disorders sense organs Both 0.1567 0.961 0.91,1.02 1393 13815 0.1722 0.961 0.907,1.02 1273 12559
381.3 Mastoiditis & related conditions sense organs Both 0.4667 0.937 0.786,1.12 126 1260 0.4406 0.932 0.779,1.11 121 1179
381.9 Otorrhea sense organs Both 0.5741 0.967 0.86,1.09 297 2960 0.7674 0.982 0.87,1.11 282 2727
382 Otalgia sense organs Both 0.4064 0.977 0.926,1.03 1425 14188 0.4477 0.978 0.924,1.04 1289 12887
383 Otosclerosis sense organs Both 0.9977 1.0 0.824,1.21 112 1120 0.4977 1.07 0.876,1.31 103 1019
384 Other disorders of tympanic membrane sense organs Both 0.9078 0.994 0.897,1.1 397 3962 0.6281 1.03 0.915,1.16 299 2955
384.4 Perforation of tympanic membrane sense organs Both 0.8279 1.01 0.904,1.14 318 3180 0.6281 1.03 0.915,1.16 299 2955
385 Other disorders of middle ear and mastoid sense organs Both 0.04266 0.893 0.801,0.996 358 3580 0.0912 0.835 0.677,1.03 100 964
385.3 Cholesteatoma sense organs Both 0.1146 0.9 0.789,1.03 245 2450 0.1671 0.911 0.799,1.04 241 2318
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.04571 0.81 0.659,0.996 103 1025 0.0912 0.835 0.677,1.03 100 964
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.1879 1.04 0.983,1.09 1441 14255 0.7962 0.996 0.966,1.03 4799 29475
386.1 Meniere's disease sense organs Both 0.7447 0.978 0.858,1.12 248 2464 0.6237 0.966 0.841,1.11 224 2234
386.2 Peripheral or central vertigo sense organs Both 0.5902 1.02 0.958,1.08 1209 11971 0.4436 0.972 0.904,1.05 781 7874
386.21 Central origin vertigo sense organs Both 0.869 1.01 0.939,1.08 883 8759 0.4436 0.972 0.904,1.05 781 7874
386.3 Labyrinthitis sense organs Both 0.4246 1.03 0.964,1.09 1099 10904 0.9863 1.0 0.938,1.07 980 9837
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.7691 1.0 0.975,1.03 5315 31605 0.7962 0.996 0.966,1.03 4799 29475
388 Other disorders of ear sense organs Both 0.4688 0.972 0.9,1.05 699 6960 0.5023 0.973 0.898,1.05 636 6391
389 Hearing loss sense organs Both 0.4477 0.989 0.962,1.02 6285 31750 0.1219 0.848 0.688,1.05 95 929
389.1 Sensorineural hearing loss sense organs Both 0.2698 0.979 0.943,1.02 3130 24231 0.3334 0.981 0.943,1.02 2880 22347
389.2 Conductive hearing loss sense organs Both 0.6209 0.981 0.909,1.06 717 7169 0.9268 0.996 0.921,1.08 676 6650
389.3 Degenerative and vascular disorders of ear sense organs Both 0.1941 0.895 0.758,1.06 143 1338 0.1982 0.891 0.748,1.06 127 1217
389.4 Tinnitus sense organs Both 0.6501 0.988 0.94,1.04 1677 16701 0.4732 0.981 0.931,1.03 1535 15437
389.5 Disorders of acoustic nerve sense organs Both 0.1589 0.864 0.705,1.06 101 1010 0.1219 0.848 0.688,1.05 95 929
394 Rheumatic disease of the heart valves circulatory system Both 0.271 0.967 0.91,1.03 1177 11253 0.811 0.988 0.896,1.09 444 4236
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.5012 1.04 0.923,1.18 284 2766 0.3483 1.06 0.937,1.2 267 2610
394.2 Mitral valve disease circulatory system Both 0.1954 0.932 0.839,1.04 378 3735 0.4786 0.961 0.861,1.07 351 3413
394.3 Aortic valve disease circulatory system Both 0.7691 1.03 0.867,1.21 150 1465 0.743 1.03 0.867,1.22 143 1409
394.7 Disease of tricuspid valve circulatory system Both 0.7031 0.982 0.892,1.08 468 4624 0.811 0.988 0.896,1.09 444 4236
395 Heart valve disorders circulatory system Both 0.7925 0.995 0.959,1.03 3169 23926 0.4634 1.03 0.956,1.1 841 7796
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.1986 0.968 0.922,1.02 1754 16787 0.354 0.976 0.926,1.03 1576 15273
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.9683 0.999 0.948,1.05 1619 13932 0.8375 1.01 0.954,1.06 1540 13102
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.118 0.918 0.824,1.02 373 3704 0.3388 0.948 0.85,1.06 357 3412
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.5808 1.06 0.857,1.32 84 831 0.6039 1.06 0.85,1.32 80 776
395.6 Heart valve replaced circulatory system Both 0.6353 1.02 0.948,1.09 878 8213 0.4634 1.03 0.956,1.1 841 7796
396 Abnormal heart sounds circulatory system Both 0.5433 0.989 0.956,1.02 3754 28453 0.4198 0.985 0.95,1.02 3365 26287
401 Hypertension circulatory system Both 0.7621 0.996 0.974,1.02 18784 19071 0.8913 1.0 0.955,1.05 1853 11918
401.1 Essential hypertension circulatory system Both 0.7499 0.996 0.974,1.02 18655 19070 0.7079 0.995 0.972,1.02 17376 17709
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.8974 1.0 0.959,1.05 2599 12045 0.5058 1.02 0.967,1.07 1927 10079
401.21 Hypertensive heart disease circulatory system Both 0.2506 0.949 0.868,1.04 556 4628 0.3811 0.959 0.874,1.05 516 4289
401.22 Hypertensive chronic kidney disease circulatory system Both 0.5508 1.02 0.966,1.07 2015 10909 0.5058 1.02 0.967,1.07 1927 10079
401.3 Other hypertensive complications circulatory system Both 0.5559 1.01 0.967,1.06 2027 12961 0.8913 1.0 0.955,1.05 1853 11918
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.7244 0.992 0.947,1.04 2132 15248 0.4498 0.982 0.935,1.03 1918 13989
411 Ischemic Heart Disease circulatory system Both 0.7211 0.995 0.967,1.02 6970 25468 0.863 1.01 0.901,1.13 319 3041
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.6383 0.981 0.907,1.06 702 6842 0.9616 0.998 0.921,1.08 667 6423
411.2 Myocardial infarction circulatory system Both 0.9954 1.0 0.96,1.04 2849 17983 0.7638 1.01 0.966,1.05 2733 16638
411.3 Angina pectoris circulatory system Both 0.867 0.996 0.949,1.04 1904 15218 0.871 1.0 0.956,1.05 1809 14129
411.4 Coronary atherosclerosis circulatory system Both 0.3724 0.986 0.957,1.02 5938 22890 0.3631 0.914 0.753,1.11 111 1075
411.41 Aneurysm and dissection of heart circulatory system Both 0.3483 0.914 0.757,1.1 117 1149 0.3631 0.914 0.753,1.11 111 1075
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.2404 0.981 0.949,1.01 4877 21174 0.3864 0.985 0.953,1.02 4669 19483
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.9484 0.996 0.891,1.11 335 3247 0.863 1.01 0.901,1.13 319 3041
414 Other forms of chronic heart disease circulatory system Both 0.877 1.0 0.961,1.05 2360 18485 0.5888 1.03 0.933,1.13 470 4543
414.2 ASCVD circulatory system Both 0.8318 1.01 0.92,1.11 492 4846 0.5888 1.03 0.933,1.13 470 4543
415 Pulmonary heart disease circulatory system Both 0.7278 0.993 0.954,1.03 2726 25061 0.6516 1.02 0.935,1.11 557 5414
415.1 Acute pulmonary heart disease circulatory system Both 0.6412 0.987 0.937,1.04 1510 15045 0.6081 0.986 0.933,1.04 1384 13960
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.6339 0.987 0.936,1.04 1507 15014 0.6081 0.986 0.933,1.04 1384 13960
415.2 Chronic pulmonary heart disease circulatory system Both 0.5808 1.02 0.962,1.07 1506 14839 0.6516 1.02 0.935,1.11 557 5414
415.21 Primary pulmonary hypertension circulatory system Both 0.5559 1.03 0.943,1.12 592 5901 0.6516 1.02 0.935,1.11 557 5414
416 Cardiomegaly circulatory system Both 0.8511 1.01 0.941,1.08 935 9293 0.9226 0.997 0.93,1.07 869 8615
418 Nonspecific chest pain circulatory system Both 0.867 0.998 0.975,1.02 10015 28233 0.8091 1.01 0.946,1.07 1087 10941
418.1 Precordial pain circulatory system Both 0.7762 1.01 0.95,1.07 1193 11816 0.8091 1.01 0.946,1.07 1087 10941
420 Carditis circulatory system Both 0.2244 1.04 0.978,1.1 1275 12633 0.3639 1.04 0.955,1.13 570 5576
420.1 Myocarditis circulatory system Both 0.2799 1.14 0.902,1.43 76 752 0.2812 1.14 0.899,1.44 73 704
420.2 Pericarditis circulatory system Both 0.743 1.01 0.937,1.1 684 6830 0.5309 0.929 0.737,1.17 80 844
420.21 Acute pericarditis circulatory system Both 0.4246 0.933 0.786,1.11 144 1435 0.241 0.897 0.748,1.08 126 1339
420.22 Chronic pericarditis circulatory system Both 0.6792 0.956 0.771,1.18 92 912 0.5309 0.929 0.737,1.17 80 844
420.3 Endocarditis circulatory system Both 0.5346 1.03 0.944,1.12 602 5990 0.3639 1.04 0.955,1.13 570 5576
425 Cardiomyopathy circulatory system Both 0.6918 1.01 0.96,1.06 1617 15758 0.1614 1.21 0.926,1.59 60 643
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.8356 1.01 0.954,1.06 1557 15170 0.3177 0.918 0.776,1.09 148 1438
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.857 1.01 0.867,1.19 171 1699 0.8035 1.02 0.87,1.2 166 1602
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.1941 0.897 0.761,1.06 154 1540 0.3177 0.918 0.776,1.09 148 1438
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.8054 0.983 0.861,1.12 248 2480 0.507 0.952 0.823,1.1 205 2332
425.8 Other cardiomyopathy circulatory system Both 0.09333 1.24 0.965,1.6 71 709 0.1614 1.21 0.926,1.59 60 643
426 Cardiac conduction disorders circulatory system Both 0.8954 1.0 0.977,1.03 9881 21221 0.1644 1.06 0.976,1.16 604 5451
426.2 Atrioventricular [AV] block circulatory system Both 0.4285 0.978 0.924,1.03 1527 9610 0.2679 0.91 0.771,1.08 151 1393
426.21 First degree AV block circulatory system Both 0.7079 0.987 0.924,1.06 1064 7510 0.5888 0.981 0.917,1.05 1012 7075
426.22 Mobitz II AV block circulatory system Both 0.5649 0.92 0.692,1.22 56 513 0.1472 0.799 0.589,1.08 51 479
426.23 Second degree AV block circulatory system Both 0.9183 0.991 0.838,1.17 161 1459 0.5284 0.946 0.796,1.12 153 1391
426.24 Atrioventricular block, complete circulatory system Both 0.6457 0.974 0.87,1.09 357 3041 0.6166 0.971 0.865,1.09 335 2859
426.25 Other heart block circulatory system Both 0.2917 0.916 0.779,1.08 161 1489 0.2679 0.91 0.771,1.08 151 1393
426.3 Bundle branch block circulatory system Both 0.3141 0.974 0.925,1.03 1775 11373 0.867 0.993 0.916,1.08 677 5787
426.31 Right bundle branch block circulatory system Both 0.2333 0.962 0.902,1.03 1101 8763 0.3006 0.966 0.905,1.03 1050 8242
426.32 Left bundle branch block circulatory system Both 0.881 0.994 0.919,1.08 721 6217 0.867 0.993 0.916,1.08 677 5787
426.4 Anomalous atrioventricular excitation circulatory system Both 0.1791 0.836 0.644,1.09 62 611 0.4325 0.895 0.679,1.18 57 574
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.8356 1.0 0.976,1.03 8452 21094 0.9141 0.998 0.971,1.03 7776 19676
426.8 Other cardiac conduction disorders circulatory system Both 0.03548 1.11 1.01,1.22 456 4529 0.0389 1.11 1.01,1.23 414 4192
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.8279 1.01 0.948,1.07 1261 8802 0.1644 1.06 0.976,1.16 604 5451
426.91 Cardiac pacemaker in situ circulatory system Both 0.4027 1.03 0.958,1.11 836 6124 0.4436 1.03 0.955,1.11 797 5763
426.92 Cardiac defibrillator in situ circulatory system Both 0.1563 1.06 0.977,1.15 628 5698 0.1644 1.06 0.976,1.16 604 5451
427 Cardiac dysrhythmias circulatory system Both 0.4943 0.992 0.971,1.01 14018 21321 0.3342 0.981 0.944,1.02 3059 18742
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.3758 0.978 0.932,1.03 1882 14769 0.8166 0.992 0.923,1.07 845 7559
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.3681 0.973 0.916,1.03 1193 11216 0.3155 0.968 0.909,1.03 1088 10412
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.867 1.01 0.938,1.08 892 7975 0.8166 0.992 0.923,1.07 845 7559
427.2 Atrial fibrillation and flutter circulatory system Both 0.3148 0.981 0.946,1.02 4194 15493 0.9036 1.0 0.949,1.06 1521 9107
427.21 Atrial fibrillation circulatory system Both 0.3581 0.983 0.947,1.02 4097 15312 0.542 0.988 0.951,1.03 3888 14209
427.22 Atrial flutter circulatory system Both 0.9616 1.0 0.948,1.06 1598 9674 0.9036 1.0 0.949,1.06 1521 9107
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.455 0.989 0.962,1.02 7129 21276 0.5754 0.992 0.964,1.02 6631 19859
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.3767 0.956 0.866,1.06 419 4137 0.2275 0.931 0.829,1.05 308 3037
427.41 Ventricular fibrillation and flutter circulatory system Both 0.3981 1.07 0.914,1.26 167 1670 0.3981 1.07 0.912,1.26 160 1608
427.42 Cardiac arrest circulatory system Both 0.1132 0.912 0.813,1.02 321 3186 0.2275 0.931 0.829,1.05 308 3037
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.8913 0.998 0.968,1.03 5521 21271 0.9908 1.0 0.969,1.03 5148 19853
427.6 Premature beats circulatory system Both 0.354 0.977 0.929,1.03 1820 13218 0.6252 1.02 0.929,1.13 466 4507
427.61 Supraventricular premature beats circulatory system Both 0.7464 1.02 0.926,1.11 522 4879 0.6252 1.02 0.929,1.13 466 4507
427.7 Tachycardia NOS circulatory system Both 0.2723 1.02 0.985,1.05 3980 21286 0.4742 1.01 0.978,1.05 3609 19869
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.7638 1.01 0.937,1.09 738 6224 0.6209 1.02 0.942,1.1 686 5767
427.9 Palpitations circulatory system Both 0.3266 0.982 0.947,1.02 3420 20157 0.3342 0.981 0.944,1.02 3059 18742
428 Congestive heart failure; nonhypertensive circulatory system Both 0.1151 1.03 0.993,1.07 3326 19946 0.04677 1.07 1.0,1.13 1127 9806
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.1153 1.03 0.992,1.07 2965 19130 0.04467 1.04 1.0,1.09 2792 17757
428.2 Heart failure NOS circulatory system Both 0.1496 1.03 0.989,1.07 2781 17962 0.1064 1.04 0.993,1.08 2614 16703
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.4977 1.02 0.963,1.08 1288 11396 0.6637 1.01 0.955,1.08 1211 10757
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.1377 1.05 0.986,1.11 1208 10616 0.04677 1.07 1.0,1.13 1127 9806
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.7244 0.996 0.972,1.02 9394 27581 0.08511 0.926 0.849,1.01 562 5485
429.1 Heart transplant/surgery circulatory system Both 0.4529 0.973 0.905,1.05 823 8070 0.4624 0.973 0.904,1.05 789 7704
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.8995 1.0 0.97,1.04 4445 23965 0.9572 1.0 0.967,1.04 4085 22191
429.3 Symptoms involving cardiovascular system circulatory system Both 0.9268 1.0 0.975,1.03 7147 27443 0.9397 0.999 0.972,1.03 6531 25590
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.05888 0.921 0.846,1.0 591 5816 0.08511 0.926 0.849,1.01 562 5485
430 Intracranial hemorrhage circulatory system Both 0.8241 0.991 0.913,1.08 633 6305 0.743 0.975 0.841,1.13 188 1877
430.1 Subarachnoid hemorrhage circulatory system Both 0.869 1.01 0.884,1.16 230 2300 0.4955 1.05 0.913,1.21 212 2112
430.2 Intracerebral hemorrhage circulatory system Both 0.9354 0.995 0.885,1.12 314 3132 0.8128 0.985 0.872,1.11 288 2898
430.3 Subdural hemorrhage circulatory system Both 0.7228 0.974 0.844,1.12 202 2017 0.743 0.975 0.841,1.13 188 1877
433 Cerebrovascular disease circulatory system Both 0.1932 0.979 0.947,1.01 4361 26660 0.1928 0.94 0.855,1.03 487 4879
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.1941 0.965 0.915,1.02 1533 12978 0.6902 0.947 0.725,1.24 57 565
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.5888 1.04 0.897,1.21 188 1858 0.6067 1.04 0.893,1.21 180 1715
433.12 Cerebral atherosclerosis circulatory system Both 0.8204 0.971 0.75,1.26 61 599 0.6902 0.947 0.725,1.24 57 565
433.2 Occlusion of cerebral arteries circulatory system Both 0.8166 0.994 0.949,1.04 1926 17593 0.6982 1.01 0.961,1.06 1738 15668
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.7798 0.993 0.947,1.04 1862 17011 0.6982 1.01 0.961,1.06 1738 15668
433.3 Cerebral ischemia circulatory system Both 0.2168 0.972 0.929,1.02 2122 18040 0.4169 0.979 0.931,1.03 1678 14764
433.31 Transient cerebral ischemia circulatory system Both 0.2223 0.97 0.924,1.02 1812 16062 0.4169 0.979 0.931,1.03 1678 14764
433.5 Cerebral aneurysm circulatory system Both 0.8913 0.993 0.896,1.1 408 4070 0.5702 1.03 0.926,1.15 374 3650
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.2399 1.07 0.958,1.18 383 3803 0.1268 1.09 0.976,1.22 356 3500
433.8 Late effects of cerebrovascular disease circulatory system Both 0.1233 0.932 0.852,1.02 534 5286 0.1928 0.94 0.855,1.03 487 4879
440 Atherosclerosis circulatory system Both 0.2366 1.03 0.982,1.08 1946 16499 0.2924 1.04 0.963,1.13 654 6355
440.1 Atherosclerosis of renal artery circulatory system Both 0.8974 0.99 0.85,1.15 187 1855 0.8147 0.981 0.838,1.15 175 1676
440.2 Atherosclerosis of the extremities circulatory system Both 0.04786 1.06 1.0,1.13 1166 11265 0.263 1.04 0.968,1.12 766 7428
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.07762 1.15 0.985,1.34 183 1815 0.08318 1.15 0.982,1.34 178 1732
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.4624 1.03 0.956,1.11 812 7979 0.263 1.04 0.968,1.12 766 7428
440.9 Atherosclerosis of aorta circulatory system Both 0.3155 1.04 0.963,1.12 702 6800 0.2924 1.04 0.963,1.13 654 6355
441 Vascular insufficiency of intestine circulatory system Both 0.1738 1.07 0.969,1.19 407 4039 0.001514 1.37 1.13,1.66 114 1070
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.5224 0.954 0.827,1.1 206 2025 0.7194 0.974 0.841,1.13 197 1854
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.002042 1.34 1.11,1.61 122 1207 0.001514 1.37 1.13,1.66 114 1070
442 Other aneurysm circulatory system Both 0.3041 0.977 0.936,1.02 2309 18098 0.3062 1.06 0.946,1.19 307 3058
442.1 Aortic aneurysm circulatory system Both 0.3373 0.976 0.927,1.03 1703 13812 0.9354 0.997 0.933,1.07 964 8584
442.11 Abdominal aortic aneurysm circulatory system Both 0.7962 0.991 0.928,1.06 992 9021 0.9354 0.997 0.933,1.07 964 8584
442.2 Aneurysm of iliac artery circulatory system Both 0.7516 1.03 0.878,1.2 177 1769 0.7096 1.03 0.882,1.2 174 1713
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.7112 1.03 0.869,1.23 137 1357 0.6776 1.04 0.871,1.24 133 1295
442.4 Arterial dissection circulatory system Both 0.4786 0.942 0.8,1.11 156 1555 0.6412 0.962 0.816,1.13 152 1480
442.8 Aneurysm of other specified artery circulatory system Both 0.3882 1.05 0.939,1.17 330 3300 0.3062 1.06 0.946,1.19 307 3058
443 Peripheral vascular disease circulatory system Both 0.2203 1.03 0.984,1.07 2355 20353 0.1476 1.04 0.987,1.09 1658 14075
443.1 Raynaud's syndrome circulatory system Both 0.6442 1.02 0.939,1.11 608 6051 0.1841 1.06 0.973,1.16 552 5382
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.6194 1.05 0.878,1.24 141 1375 0.6653 1.04 0.87,1.24 134 1270
443.8 Other specified peripheral vascular diseases circulatory system Both 0.5534 1.01 0.968,1.06 1899 17476 0.1968 1.03 0.983,1.08 1793 16090
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.3133 1.03 0.976,1.08 1747 15154 0.1476 1.04 0.987,1.09 1658 14075
444 Arterial embolism and thrombosis circulatory system Both 0.7516 0.987 0.912,1.07 675 6732 0.3864 1.09 0.901,1.31 125 1209
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.6839 1.03 0.9,1.17 240 2392 0.6653 1.03 0.9,1.18 231 2254
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.4325 1.08 0.896,1.29 129 1282 0.3864 1.09 0.901,1.31 125 1209
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.6194 1.03 0.923,1.14 367 3641 0.7328 1.02 0.892,1.18 217 2077
446.4 Wegener's granulomatosis circulatory system Both 0.6966 1.04 0.844,1.29 86 857 0.7311 1.04 0.837,1.29 82 780
446.5 Giant cell arteritis circulatory system Both 0.6776 0.942 0.712,1.25 59 547 ,
446.9 Arteritis NOS circulatory system Both 0.9141 0.993 0.868,1.14 230 2285 0.7328 1.02 0.892,1.18 217 2077
447 Other disorders of arteries and arterioles circulatory system Both 0.375 0.98 0.937,1.02 2116 18819 0.1091 0.934 0.86,1.02 615 6048
447.1 Stricture of artery circulatory system Both 0.2773 1.06 0.958,1.16 435 4322 0.1327 1.08 0.977,1.19 408 3975
447.7 Aortic ectasia circulatory system Both 0.08511 0.931 0.857,1.01 637 6315 0.1091 0.934 0.86,1.02 615 6048
448 Disease of capillaries circulatory system Both 0.6714 0.985 0.918,1.06 853 8472 0.5047 0.975 0.905,1.05 760 7620
450 Noninfectious disorders of lymphatic channels circulatory system Both 1.096E-4 1.1 1.05,1.16 1701 17006 0.6427 1.01 0.954,1.08 1082 15555
451 Phlebitis and thrombophlebitis circulatory system Both 0.2421 0.951 0.874,1.03 582 5764 0.07586 0.869 0.744,1.01 172 1735
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.06457 0.87 0.75,1.01 190 1888 0.07586 0.869 0.744,1.01 172 1735
452 Other venous embolism and thrombosis circulatory system Both 0.863 0.997 0.963,1.03 3773 25068 0.4111 1.08 0.896,1.31 114 1117
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.1778 0.91 0.793,1.04 228 2277 0.1897 0.909 0.788,1.05 210 2119
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.526 0.987 0.948,1.03 2623 22444 0.5458 0.987 0.947,1.03 2445 21116
452.8 Postphlebitic syndrome circulatory system Both 0.6368 1.05 0.868,1.26 119 1181 0.4111 1.08 0.896,1.31 114 1117
453 Chronic venous hypertension circulatory system Both 0.246 1.1 0.939,1.28 173 1715 0.3412 1.08 0.92,1.27 156 1540
454 Varicose veins circulatory system Both 0.2032 1.03 0.985,1.08 2206 20243 0.6653 1.01 0.953,1.08 1060 10802
454.1 Varicose veins of lower extremity circulatory system Both 0.2606 1.03 0.98,1.08 1908 17574 0.6653 1.01 0.953,1.08 1060 10802
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.5023 1.02 0.962,1.08 1182 11754 0.6653 1.01 0.953,1.08 1060 10802
455 Hemorrhoids circulatory system Both 0.7925 1.0 0.972,1.04 4379 24588 0.6412 0.992 0.959,1.03 3917 23156
456 Chronic venous insufficiency [CVI] circulatory system Both 0.9727 1.0 0.958,1.04 2303 20367 0.7889 0.994 0.95,1.04 2072 18983
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.7998 1.01 0.959,1.06 1946 14131 0.8241 1.01 0.956,1.06 1765 12914
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.7278 0.979 0.868,1.1 287 2845 0.5781 0.966 0.853,1.09 271 2714
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.8872 1.0 0.955,1.05 1841 13661 0.8241 1.01 0.956,1.06 1765 12914
458 Hypotension circulatory system Both 0.5248 1.01 0.978,1.04 4073 28546 0.7656 1.01 0.97,1.04 3412 25401
458.1 Orthostatic hypotension circulatory system Both 0.02042 1.08 1.01,1.15 1031 10176 0.006607 1.1 1.03,1.17 955 9502
458.2 Iatrogenic hypotension circulatory system Both 0.0955 1.06 0.99,1.13 911 9084 0.1268 1.06 0.985,1.13 866 8423
458.9 Hypotension NOS circulatory system Both 0.9204 1.0 0.968,1.04 3641 27465 0.7656 1.01 0.97,1.04 3412 25401
459 Other disorders of circulatory system circulatory system Both 0.9616 0.999 0.965,1.03 3553 27674 0.9661 0.999 0.959,1.04 2544 21879
459.1 Hemorrhage NOS circulatory system Both 0.5689 1.02 0.945,1.11 619 6159 0.778 1.01 0.93,1.1 554 5658
459.7 Blood vessel replaced circulatory system Both 0.0955 0.886 0.768,1.02 203 2030 0.1346 0.896 0.777,1.03 201 1949
459.9 Circulatory disease NEC circulatory system Both 0.8299 0.996 0.957,1.04 2757 23656 0.9661 0.999 0.959,1.04 2544 21879
464 Acute sinusitis respiratory Both 0.7079 1.01 0.972,1.04 3675 26562 0.6138 0.991 0.955,1.03 3266 24658
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.7396 0.996 0.97,1.02 7223 30143 0.4831 0.959 0.854,1.08 313 3115
465.2 Acute pharyngitis respiratory Both 0.171 0.977 0.944,1.01 3967 26715 0.2178 0.978 0.944,1.01 3606 24815
465.4 Acute laryngitis and tracheitis respiratory Both 0.5794 0.969 0.868,1.08 345 3441 0.4831 0.959 0.854,1.08 313 3115
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.03388 0.943 0.893,0.996 1431 14130 0.0195 0.936 0.885,0.989 1369 13383
471 Nasal polyps respiratory Both 0.6592 1.02 0.93,1.12 475 4727 0.7211 1.02 0.924,1.12 450 4487
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.2761 0.969 0.917,1.03 1344 13251 0.2296 0.965 0.91,1.02 1229 12191
473 Diseases of the larynx and vocal cords respiratory Both 0.2655 0.976 0.935,1.02 2393 20985 0.5012 0.983 0.936,1.03 1759 16793
473.1 Chronic laryngitis respiratory Both 0.2333 0.845 0.64,1.11 57 562 0.3899 0.88 0.659,1.18 52 513
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.9683 1.0 0.915,1.1 517 5167 0.9506 1.0 0.914,1.1 484 4774
473.4 Voice disturbance respiratory Both 0.4634 0.982 0.937,1.03 1880 18033 0.5012 0.983 0.936,1.03 1759 16793
474 Acute and chronic tonsillitis respiratory Both 0.005129 0.891 0.822,0.966 685 6193 0.0138 0.893 0.815,0.977 534 4926
474.1 Acute tonsillitis respiratory Both 0.07079 0.888 0.78,1.01 267 2507 0.06457 0.884 0.775,1.01 259 2389
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.01096 0.891 0.815,0.974 555 5166 0.0138 0.893 0.815,0.977 534 4926
475 Chronic sinusitis respiratory Both 0.2477 0.979 0.944,1.01 3434 23149 0.865 0.993 0.913,1.08 595 5948
475.9 Postnasal drip respiratory Both 0.8872 0.994 0.918,1.08 651 6441 0.865 0.993 0.913,1.08 595 5948
476 Allergic rhinitis respiratory Both 0.7211 1.0 0.981,1.03 10205 23354 0.4842 0.991 0.967,1.02 9115 21994
477 Epistaxis or throat hemorrhage respiratory Both 0.7228 0.988 0.921,1.06 895 8841 0.4529 0.973 0.905,1.05 826 8281
478 Throat pain respiratory Both 0.1528 0.919 0.819,1.03 325 3233 0.1483 0.915 0.812,1.03 302 3030
479 Other upper respiratory disease respiratory Both 0.8913 1.0 0.97,1.04 4428 23338 0.7943 0.996 0.963,1.03 4122 21981
480 Pneumonia respiratory Both 0.3926 1.01 0.983,1.04 4823 30881 0.07244 0.837 0.689,1.02 113 1082
480.1 Bacterial pneumonia respiratory Both 0.8851 0.995 0.928,1.07 860 8567 0.7516 0.964 0.77,1.21 79 777
480.11 Pneumococcal pneumonia respiratory Both 0.2655 1.06 0.956,1.18 372 3720 0.4732 1.04 0.934,1.16 347 3469
480.12 Pseudomonal pneumonia respiratory Both 0.859 1.02 0.846,1.22 121 1192 0.8128 1.02 0.847,1.23 116 1111
480.13 MRSA pneumonia respiratory Both 0.8072 0.973 0.778,1.22 82 818 0.7516 0.964 0.77,1.21 79 777
480.2 Viral pneumonia respiratory Both 0.6209 1.04 0.885,1.23 147 1461 0.6368 1.04 0.879,1.24 136 1347
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.4046 1.09 0.894,1.32 117 1170 0.3673 1.1 0.896,1.35 109 1085
480.5 Bronchopneumonia and lung abscess respiratory Both 0.0257 0.804 0.664,0.974 119 1175 0.07244 0.837 0.689,1.02 113 1082
481 Influenza respiratory Both 0.8472 1.01 0.943,1.07 990 9863 0.9795 0.999 0.932,1.07 884 9045
483 Acute bronchitis and bronchiolitis respiratory Both 0.08913 1.04 0.995,1.08 2615 24227 0.1156 1.03 0.992,1.08 2326 22177
495 Asthma respiratory Both 0.7413 1.0 0.978,1.03 6951 27725 0.881 0.995 0.937,1.06 1135 11258
495.1 Chronic obstructive asthma respiratory Both 0.4966 1.04 0.931,1.16 341 3403 0.2786 1.15 0.891,1.49 53 516
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.2218 1.17 0.912,1.49 60 592 0.2786 1.15 0.891,1.49 53 516
495.2 Asthma with exacerbation respiratory Both 0.9078 1.0 0.947,1.06 1251 12442 0.881 0.995 0.937,1.06 1135 11258
496 Chronic airway obstruction respiratory Both 0.1905 1.02 0.989,1.06 4444 23893 0.02042 1.13 1.02,1.25 402 3926
496.1 Emphysema respiratory Both 0.2291 1.03 0.982,1.08 1831 16712 0.2742 1.03 0.978,1.08 1728 15497
496.2 Chronic bronchitis respiratory Both 0.8872 0.997 0.962,1.03 3357 22668 0.7568 0.994 0.955,1.03 2871 19976
496.21 Obstructive chronic bronchitis respiratory Both 0.5662 0.989 0.952,1.03 3040 21701 0.7568 0.994 0.955,1.03 2871 19976
496.3 Bronchiectasis respiratory Both 0.0195 1.12 1.02,1.24 435 4329 0.02042 1.13 1.02,1.25 402 3926
497 Bronchitis respiratory Both 0.9226 0.997 0.946,1.05 1481 14700 0.8054 1.01 0.952,1.07 1330 13282
498 Acute bronchospasm respiratory Both 0.133 1.08 0.976,1.2 376 3745 0.2339 1.07 0.958,1.19 342 3387
499 Cystic fibrosis respiratory Both 0.2999 1.11 0.914,1.34 116 1160 0.2138 1.14 0.927,1.41 97 1034
500 Lung disease due to external agents respiratory Both 0.2938 1.05 0.956,1.16 428 4273 0.5808 0.933 0.728,1.19 62 627
500.1 Extrinsic allergic alveolitis respiratory Both 0.3589 1.11 0.891,1.38 81 810 0.3296 1.13 0.888,1.43 70 710
500.2 Pneumoconiosis respiratory Both 0.5754 0.932 0.73,1.19 65 640 0.5808 0.933 0.728,1.19 62 627
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.2143 0.944 0.863,1.03 514 5078 0.2805 0.95 0.866,1.04 483 4768
502 Postinflammatory pulmonary fibrosis respiratory Both 0.2547 1.05 0.966,1.14 623 6192 0.2704 1.05 0.963,1.14 582 5709
503 Pulmonary congestion and hypostasis respiratory Both 0.9886 0.999 0.923,1.08 690 6875 0.871 0.993 0.915,1.08 646 6379
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.8241 1.01 0.917,1.11 447 4454 0.7261 0.977 0.856,1.11 234 2274
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.7047 0.976 0.858,1.11 247 2456 0.7261 0.977 0.856,1.11 234 2274
505 Other pulmonary inflamation or edema respiratory Both 0.4539 1.02 0.966,1.08 1352 13261 0.3846 1.03 0.968,1.09 1260 12366
506 Empyema and pneumothorax respiratory Both 0.4227 1.02 0.976,1.06 2588 22332 0.2427 1.03 0.983,1.07 2460 20888
507 Pleurisy; pleural effusion respiratory Both 0.2104 1.03 0.985,1.07 2415 21828 0.1265 1.03 0.99,1.08 2235 20164
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.1972 1.03 0.984,1.08 2005 19256 0.1799 1.03 0.985,1.08 1849 17880
509 Respiratory failure, insufficiency, arrest respiratory Both 0.6223 1.01 0.972,1.05 3044 23898 0.9441 0.997 0.928,1.07 800 7824
509.1 Respiratory failure respiratory Both 0.7889 1.01 0.955,1.06 1466 14560 0.6998 1.01 0.957,1.07 1385 13552
509.2 Respiratory insufficiency respiratory Both 0.9795 0.999 0.934,1.07 928 9238 0.9462 1.0 0.936,1.07 881 8636
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.5272 1.02 0.965,1.07 1500 14783 0.4018 1.02 0.97,1.08 1454 13921
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.9204 1.0 0.936,1.08 848 8472 0.9441 0.997 0.928,1.07 800 7824
510 Other diseases of lung respiratory Both 0.02239 1.04 1.01,1.07 4671 30168 0.0195 1.24 1.04,1.49 123 1201
510.2 Lung transplant respiratory Both 0.03162 1.21 1.02,1.45 128 1274 0.0195 1.24 1.04,1.49 123 1201
512 Other symptoms of respiratory system respiratory Both 0.8166 0.998 0.977,1.02 14878 23476 0.9572 0.999 0.974,1.03 8023 22021
512.1 Wheezing respiratory Both 0.9908 1.0 0.939,1.06 1071 10626 0.695 0.987 0.924,1.05 964 9750
512.2 Painful respiration respiratory Both 0.7962 0.993 0.946,1.04 1765 17029 0.3177 0.973 0.923,1.03 1510 15659
512.3 Abnormal chest sounds respiratory Both 0.0912 1.12 0.982,1.29 229 2261 0.0302 1.17 1.02,1.35 207 2078
512.7 Shortness of breath respiratory Both 0.6902 0.995 0.969,1.02 7928 23452 0.6383 0.994 0.967,1.02 7260 22007
512.8 Cough respiratory Both 0.3767 1.01 0.985,1.04 7280 23469 0.9099 0.998 0.971,1.03 6557 22027
512.9 Other dyspnea respiratory Both 0.9506 1.0 0.976,1.03 8658 23467 0.9572 0.999 0.974,1.03 8023 22021
513 Respiratory abnormalities respiratory Both 0.4276 1.01 0.986,1.03 10231 28110 0.9661 1.0 0.865,1.16 190 1955
513.3 Hypoventilation respiratory Both 0.3837 1.04 0.955,1.13 618 6146 0.5794 0.953 0.803,1.13 154 1566
513.31 Apnea respiratory Both 0.7816 1.02 0.905,1.14 314 3136 0.6166 1.03 0.915,1.16 297 2924
513.32 Orthopnea respiratory Both 0.8299 0.982 0.833,1.16 167 1662 0.5794 0.953 0.803,1.13 154 1566
513.4 Hyperventilation respiratory Both 0.826 0.989 0.897,1.09 440 4383 0.8054 1.01 0.915,1.12 411 4075
513.8 Disorders of diaphragm respiratory Both 0.9397 0.995 0.862,1.15 206 2053 0.9661 1.0 0.865,1.16 190 1955
514 Abnormal findings examination of lungs respiratory Both 0.2218 1.02 0.988,1.05 4486 29229 0.2679 1.02 0.981,1.07 2260 20998
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.9397 0.994 0.859,1.15 193 1914 0.8974 0.99 0.853,1.15 184 1758
514.2 Solitary pulmonary nodule respiratory Both 0.1422 1.03 0.99,1.08 2489 22668 0.2679 1.02 0.981,1.07 2260 20998
516 Abnormal sputum respiratory Both 0.07244 1.08 0.993,1.18 565 5640 0.103 1.08 0.984,1.2 436 4431
516.1 Hemoptysis respiratory Both 0.1954 1.06 0.969,1.17 473 4720 0.103 1.08 0.984,1.2 436 4431
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.6918 1.01 0.977,1.04 5153 32053 0.9204 0.998 0.964,1.03 3681 27091
519.1 Tracheostomy complications respiratory Both 0.4571 0.943 0.808,1.1 176 1760 0.5929 0.958 0.819,1.12 170 1654
519.2 Respiratory complications respiratory Both 0.7798 1.02 0.913,1.13 370 3696 0.8851 1.01 0.905,1.12 360 3505
519.8 Other diseases of respiratory system, NEC respiratory Both 0.9441 1.0 0.935,1.07 887 8857 0.7379 1.01 0.942,1.09 830 8210
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.6353 1.01 0.975,1.04 4043 29199 0.9204 0.998 0.964,1.03 3681 27091
520 Disorders of tooth development digestive Both 0.2259 0.928 0.821,1.05 291 2900 0.3524 0.927 0.791,1.09 168 1633
520.1 Hereditary disturbances in tooth structure digestive Both 0.1489 0.875 0.73,1.05 131 1301 0.1663 0.877 0.729,1.06 125 1226
520.2 Disturbances in tooth eruption digestive Both 0.2203 0.906 0.774,1.06 172 1693 0.3524 0.927 0.791,1.09 168 1633
521 Diseases of hard tissues of teeth digestive Both 0.7727 1.01 0.937,1.09 719 7167 0.8072 1.01 0.932,1.1 644 6309
521.1 Dental caries digestive Both 0.7379 1.01 0.936,1.1 673 6709 0.8072 1.01 0.932,1.1 644 6309
522 Diseases of pulp and periapical tissues digestive Both 0.1828 1.07 0.968,1.18 408 4067 0.01622 1.15 1.03,1.29 312 3156
522.5 Periapical abscess digestive Both 0.04786 1.12 1.0,1.25 341 3404 0.01622 1.15 1.03,1.29 312 3156
523 Gingival and periodontal diseases digestive Both 0.3266 1.04 0.958,1.14 569 5690 0.5248 0.936 0.763,1.15 100 984
523.1 Gingivitis digestive Both 0.5 0.938 0.779,1.13 117 1163 0.25 0.893 0.736,1.08 109 1096
523.3 Periodontitis (acute or chronic) digestive Both 0.5188 1.04 0.923,1.17 294 2940 0.5248 0.936 0.763,1.15 100 984
523.31 Acute periodontitis digestive Both 0.5598 1.04 0.914,1.18 251 2510 0.5559 1.04 0.913,1.19 237 2346
523.32 Chronic periodontitis digestive Both 0.5483 0.941 0.77,1.15 103 1030 0.5248 0.936 0.763,1.15 100 984
524 Dentofacial anomalies, including malocclusion digestive Both 0.879 0.991 0.881,1.11 308 3080 0.6471 0.965 0.827,1.12 184 1760
524.3 Anomalies of tooth position/malocclusion digestive Both 0.4898 0.948 0.813,1.1 186 1856 0.6471 0.965 0.827,1.12 184 1760
525 Other diseases of the teeth and supporting structures digestive Both 0.8375 0.993 0.925,1.06 853 8530 0.2897 0.937 0.83,1.06 302 2946
525.1 Loss of teeth or edentulism digestive Both 0.3112 0.941 0.837,1.06 318 3178 0.2897 0.937 0.83,1.06 302 2946
526 Diseases of the jaws digestive Both 0.317 0.978 0.935,1.02 2140 21162 0.5861 0.971 0.875,1.08 374 3683
526.1 Cysts of the jaws digestive Both 0.4365 0.947 0.825,1.09 213 2123 0.5458 0.958 0.834,1.1 210 2030
526.3 Anomalies of jaw size/symmetry digestive Both 0.1306 0.896 0.777,1.03 206 2052 0.2427 0.918 0.796,1.06 202 1944
526.4 Temporomandibular joint disorders digestive Both 0.06457 0.945 0.89,1.0 1178 11779 0.743 1.01 0.93,1.11 559 5398
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.03467 0.93 0.87,0.995 941 9410 0.07762 0.939 0.875,1.01 866 8481
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.9441 1.0 0.922,1.09 600 5993 0.743 1.01 0.93,1.11 559 5398
526.5 Inflammatory conditions of jaw digestive Both 0.9572 1.0 0.88,1.14 242 2405 0.8414 1.01 0.885,1.16 230 2230
526.9 Jaw disease NOS digestive Both 0.4335 0.96 0.868,1.06 399 3982 0.5861 0.971 0.875,1.08 374 3683
527 Diseases of the salivary glands digestive Both 0.2931 0.97 0.918,1.03 1362 13604 0.5408 1.05 0.898,1.23 180 1830
527.2 Sialoadenitis digestive Both 0.5035 0.961 0.855,1.08 320 3200 0.6982 0.976 0.865,1.1 302 2951
527.7 Disturbance of salivary secretion digestive Both 0.3811 0.967 0.896,1.04 715 7141 0.3793 0.965 0.891,1.04 656 6563
527.8 Other specified diseases of the salivary glands digestive Both 0.3228 1.08 0.929,1.25 196 1960 0.5408 1.05 0.898,1.23 180 1830
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.9078 0.997 0.953,1.04 2077 20750 0.561 1.05 0.882,1.26 129 1218
528.1 Stomatitis and mucositis digestive Both 0.03631 1.1 1.01,1.2 536 5360 0.5834 0.956 0.813,1.12 158 1547
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.5105 1.05 0.9,1.24 165 1650 0.2244 1.11 0.937,1.32 139 1488
528.12 Oral aphthae digestive Both 0.811 0.981 0.839,1.15 170 1700 0.5834 0.956 0.813,1.12 158 1547
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.2541 0.916 0.788,1.07 185 1837 0.3908 0.934 0.799,1.09 175 1711
528.4 Cysts of oral soft tissues digestive Both 0.2208 0.885 0.729,1.08 110 1096 0.1786 0.834 0.641,1.09 62 622
528.41 Cyst of the salivary gland digestive Both 0.1099 0.815 0.634,1.05 68 679 0.1786 0.834 0.641,1.09 62 622
528.5 Diseases of lips digestive Both 0.02512 0.881 0.789,0.984 334 3340 0.06026 0.896 0.8,1.0 308 3033
528.6 Leukoplakia of oral mucosa digestive Both 0.4808 1.07 0.884,1.3 113 1120 0.5023 1.07 0.876,1.31 105 1042
528.7 Sialolithiasis digestive Both 0.7464 1.03 0.864,1.23 132 1320 0.561 1.05 0.882,1.26 129 1218
529 Diseases and other conditions of the tongue digestive Both 0.5445 0.973 0.891,1.06 541 5402 0.6622 1.04 0.867,1.25 123 1236
529.1 Glossitis digestive Both 0.271 1.12 0.915,1.37 99 982 0.1991 1.15 0.929,1.42 88 881
529.6 Glossodynia digestive Both 0.6368 1.04 0.877,1.24 136 1355 0.6622 1.04 0.867,1.25 123 1236
530 Diseases of esophagus digestive Both 0.6699 0.995 0.974,1.02 13874 23034 0.9727 1.0 0.94,1.07 1093 10866
530.1 Esophagitis, GERD and related diseases digestive Both 0.6561 0.995 0.974,1.02 13419 23031 0.4634 0.938 0.791,1.11 136 1349
530.11 GERD digestive Both 0.6053 0.994 0.973,1.02 13059 23031 0.5741 0.993 0.971,1.02 11988 21528
530.12 Ulcer of esophagus digestive Both 0.3034 1.06 0.945,1.2 298 2973 0.2168 1.08 0.956,1.22 280 2765
530.13 Barrett's esophagus digestive Both 0.9977 1.0 0.92,1.09 609 6080 0.9162 0.995 0.913,1.08 576 5753
530.14 Reflux esophagitis digestive Both 0.4887 0.981 0.93,1.04 1483 14213 0.8035 1.01 0.952,1.07 1337 12969
530.15 Eosinophilic esophagitis digestive Both 0.3573 0.925 0.784,1.09 145 1441 0.4634 0.938 0.791,1.11 136 1349
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.5662 1.03 0.935,1.13 475 4742 0.3864 1.04 0.947,1.15 451 4448
530.3 Stricture and stenosis of esophagus digestive Both 0.2812 1.04 0.967,1.12 752 7474 0.3289 1.04 0.962,1.12 698 6873
530.5 Disorders of esophageal motility digestive Both 0.3062 0.95 0.86,1.05 434 4326 0.3864 0.955 0.861,1.06 396 3880
530.6 Diverticulum of esophagus, acquired digestive Both 0.7816 0.973 0.803,1.18 121 1181 0.9484 0.994 0.819,1.21 116 1116
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.7178 0.956 0.747,1.22 70 700 0.618 0.937 0.727,1.21 65 661
530.9 Heartburn digestive Both 0.7178 0.989 0.931,1.05 1198 11946 0.9727 1.0 0.94,1.07 1093 10866
531 Peptic ulcer (excl. esophageal) digestive Both 0.123 1.04 0.989,1.1 1608 16066 0.05754 0.824 0.675,1.01 106 1019
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.6026 0.969 0.861,1.09 311 3103 0.7345 0.979 0.869,1.1 302 2893
531.2 Gastric ulcer digestive Both 0.06761 1.07 0.995,1.14 884 8834 0.04074 1.08 1.0,1.16 829 8132
531.3 Duodenal ulcer digestive Both 0.2735 1.06 0.953,1.19 362 3613 0.3483 1.06 0.943,1.18 343 3406
531.4 Peptic ulcer, site unspecified digestive Both 0.7063 1.02 0.937,1.1 632 6313 0.4909 1.03 0.947,1.12 586 5731
531.5 Gastrojejunal ulcer digestive Both 0.02818 0.807 0.666,0.977 115 1143 0.05754 0.824 0.675,1.01 106 1019
532 Dysphagia digestive Both 0.00912 0.957 0.927,0.989 4457 22190 0.01318 0.958 0.926,0.991 4155 20691
535 Gastritis and duodenitis digestive Both 0.08913 1.04 0.994,1.09 2129 21208 0.8892 1.0 0.938,1.08 877 8959
535.1 Acute gastritis digestive Both 0.07943 1.07 0.992,1.14 814 8139 0.06026 1.07 0.997,1.16 749 7443
535.2 Atrophic gastritis digestive Both 0.03388 1.15 1.01,1.32 250 2500 0.02239 1.17 1.02,1.35 232 2282
535.6 Duodenitis digestive Both 0.05129 1.13 0.999,1.29 265 2650 0.04169 1.14 1.01,1.3 252 2488
535.8 Other specified gastritis digestive Both 0.8551 0.991 0.904,1.09 497 4964 0.8551 1.01 0.916,1.11 454 4547
535.9 Gastritis and duodenitis, NOS digestive Both 0.6095 1.02 0.953,1.09 985 9835 0.8892 1.0 0.938,1.08 877 8959
536 Disorders of function of stomach digestive Both 0.3126 0.978 0.936,1.02 2251 22311 0.2799 0.971 0.921,1.02 1533 15318
536.3 Gastroparesis digestive Both 0.9204 0.995 0.908,1.09 489 4876 0.7079 1.02 0.925,1.12 450 4411
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.07586 0.904 0.808,1.01 334 3331 0.0955 0.907 0.808,1.02 313 3066
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.6839 0.99 0.941,1.04 1699 16834 0.2799 0.971 0.921,1.02 1533 15318
537 Other disorders of stomach and duodenum digestive Both 0.3908 0.982 0.941,1.02 2357 23199 0.415 1.08 0.898,1.3 118 1183
537.1 Lesions of stomach and duodenum digestive Both 0.3819 1.08 0.907,1.29 128 1271 0.415 1.08 0.898,1.3 118 1183
539 Bariatric surgery digestive Both 0.8954 1.0 0.945,1.07 1118 11180 0.5715 1.02 0.956,1.09 1040 10007
540 Appendiceal conditions digestive Both 0.1507 1.08 0.973,1.19 399 3990 0.1064 1.11 0.978,1.26 267 2700
540.1 Appendicitis digestive Both 0.2312 1.07 0.959,1.19 349 3490 0.1064 1.11 0.978,1.26 267 2700
540.11 Acute appendicitis digestive Both 0.1213 1.1 0.975,1.24 293 2930 0.1064 1.11 0.978,1.26 267 2700
550 Abdominal hernia digestive Both 0.07943 0.974 0.947,1.0 5517 31191 0.4955 0.978 0.917,1.04 1024 10120
550.1 Inguinal hernia digestive Both 0.5984 0.985 0.933,1.04 1427 13556 0.6918 0.989 0.936,1.04 1401 13207
550.2 Diaphragmatic hernia digestive Both 0.6223 0.989 0.948,1.03 2290 21266 0.879 1.0 0.959,1.05 2104 19292
550.3 Femoral hernia digestive Both 0.5176 1.07 0.878,1.29 109 1082 0.2851 1.12 0.911,1.37 102 977
550.4 Umbilical hernia digestive Both 0.6745 0.986 0.925,1.05 1053 10514 0.7691 0.99 0.927,1.06 1002 9992
550.5 Ventral hernia digestive Both 0.2065 0.969 0.924,1.02 1826 18190 0.3365 0.976 0.928,1.03 1712 16759
550.6 Incisional hernia digestive Both 0.3573 0.971 0.912,1.03 1101 10999 0.4955 0.978 0.917,1.04 1024 10120
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.01995 1.07 1.01,1.13 1275 12527 0.001148 1.18 1.07,1.31 411 4106
555.1 Regional enteritis digestive Both 0.04467 1.08 1.0,1.16 775 7701 0.04365 1.08 1.0,1.16 736 7217
555.2 Ulcerative colitis digestive Both 0.01413 1.1 1.02,1.18 768 7591 0.001148 1.18 1.07,1.31 411 4106
555.21 Ulcerative colitis (chronic) digestive Both 7.413E-4 1.18 1.07,1.31 438 4361 0.001148 1.18 1.07,1.31 411 4106
556 Ulceration of the lower GI tract digestive Both 0.7745 0.986 0.899,1.08 473 4719 0.7727 1.03 0.861,1.22 140 1403
556.1 Ulceration of intestine digestive Both 0.6918 0.98 0.887,1.08 412 4099 0.7727 1.03 0.861,1.22 140 1403
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.5848 1.05 0.885,1.24 152 1496 0.7727 1.03 0.861,1.22 140 1403
557 Intestinal malabsorption (non-celiac) digestive Both 0.9638 0.999 0.943,1.06 1306 12565 0.2317 0.928 0.82,1.05 283 2759
557.1 Celiac disease digestive Both 0.123 0.911 0.808,1.03 305 3050 0.2317 0.928 0.82,1.05 283 2759
558 Noninfectious gastroenteritis digestive Both 0.9354 0.998 0.959,1.04 2706 20417 0.9354 1.0 0.96,1.04 2489 19102
559 Ileostomy status digestive Both 0.9638 0.998 0.928,1.07 773 7702 0.9594 1.0 0.93,1.08 748 7268
560 Intestinal obstruction without mention of hernia digestive Both 0.1503 0.97 0.931,1.01 2580 20303 0.873 0.996 0.942,1.05 1403 13367
560.1 Paralytic ileus digestive Both 0.1626 0.962 0.911,1.02 1429 13524 0.1923 0.964 0.911,1.02 1363 12744
560.2 Impaction of intestine digestive Both 0.6209 0.968 0.853,1.1 257 2499 0.4426 0.948 0.828,1.09 227 2242
560.3 Peritoneal or intestinal adhesions digestive Both 0.1556 0.911 0.802,1.04 261 2599 0.0871 0.892 0.782,1.02 245 2367
560.4 Other intestinal obstruction digestive Both 0.7244 0.99 0.939,1.04 1489 14381 0.873 0.996 0.942,1.05 1403 13367
561 Symptoms involving digestive system digestive Both 0.9247 1.0 0.975,1.03 7750 22039 0.9247 1.0 0.958,1.05 2146 17673
561.1 Diarrhea digestive Both 0.9247 0.999 0.97,1.03 5986 22042 0.3631 0.986 0.956,1.02 5408 20718
561.2 Flatulence digestive Both 0.8851 0.997 0.955,1.04 2358 18995 0.9247 1.0 0.958,1.05 2146 17673
562 Diverticulosis and diverticulitis digestive Both 0.375 0.986 0.954,1.02 5014 18500 0.2323 0.964 0.908,1.02 1177 11265
562.1 Diverticulosis digestive Both 0.3882 0.986 0.955,1.02 4973 18448 0.1208 0.974 0.941,1.01 4486 17173
562.2 Diverticulitis digestive Both 0.2773 0.969 0.915,1.03 1292 12242 0.2323 0.964 0.908,1.02 1177 11265
563 Constipation digestive Both 0.5808 1.01 0.979,1.04 5639 22004 0.7907 0.996 0.965,1.03 5125 20679
564 Functional digestive disorders digestive Both 0.6109 0.994 0.97,1.02 9553 22037 0.5741 0.986 0.937,1.04 1635 15290
564.1 Irritable Bowel Syndrome digestive Both 0.4467 0.984 0.945,1.03 2751 17147 0.2133 0.973 0.932,1.02 2475 15834
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.8128 0.995 0.953,1.04 2348 18710 0.5834 0.988 0.944,1.03 2171 17444
564.9 Personal history of diseases of digestive system digestive Both 0.5212 0.984 0.937,1.03 1762 16521 0.5741 0.986 0.937,1.04 1635 15290
565 Anal and rectal conditions digestive Both 0.6223 0.99 0.95,1.03 2533 24500 0.9247 1.0 0.935,1.08 832 8580
565.1 Anal and rectal polyp digestive Both 0.7328 1.01 0.946,1.08 932 9300 0.9247 1.0 0.935,1.08 832 8580
567 Peritonitis and retroperitoneal infections digestive Both 0.4046 1.03 0.966,1.09 1149 11482 0.5 1.02 0.96,1.09 1083 10684
568 Other disorders of peritoneum digestive Both 0.02884 0.942 0.893,0.994 1452 14494 0.01585 0.924 0.866,0.985 1025 9907
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.003631 0.911 0.856,0.97 1076 10752 0.01585 0.924 0.866,0.985 1025 9907
569 Other disorders of intestine digestive Both 0.2831 0.985 0.959,1.01 6343 29512 0.9931 1.0 0.941,1.06 1148 11212
569.1 Toxic gastroenteritis and colitis digestive Both 0.6138 1.03 0.909,1.17 251 2510 0.8954 0.99 0.857,1.14 195 2320
569.2 Gastrointestinal complications digestive Both 0.7603 0.991 0.934,1.05 1206 12058 0.9931 1.0 0.941,1.06 1148 11212
571 Chronic liver disease and cirrhosis digestive Both 0.1683 1.02 0.99,1.06 3603 27394 0.5297 1.03 0.935,1.14 422 4163
571.5 Other chronic nonalcoholic liver disease digestive Both 0.1936 1.02 0.988,1.06 3388 27100 0.6012 1.02 0.946,1.1 743 7319
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.9484 0.998 0.927,1.07 781 7802 0.6012 1.02 0.946,1.1 743 7319
571.6 Primary biliary cirrhosis digestive Both 0.4943 1.06 0.894,1.26 146 1460 0.2748 1.1 0.924,1.32 137 1365
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.859 1.01 0.934,1.09 749 7472 0.5297 1.03 0.935,1.14 422 4163
571.81 Portal hypertension digestive Both 0.7178 1.02 0.924,1.12 441 4400 0.5297 1.03 0.935,1.14 422 4163
572 Ascites (non malignant) digestive Both 0.9638 1.0 0.955,1.05 1884 18805 0.9772 1.0 0.953,1.05 1744 17441
573 Other disorders of liver digestive Both 0.4074 1.01 0.982,1.05 4460 28151 0.9016 0.998 0.961,1.04 3043 26185
573.1 Chronic passive congestion of liver digestive Both 0.7889 1.03 0.838,1.26 100 991 0.8851 1.02 0.825,1.25 96 955
573.2 Liver replaced by transplant digestive Both 0.302 1.07 0.937,1.23 227 2268 0.4055 1.06 0.923,1.22 218 2152
573.3 Hepatomegaly digestive Both 0.6577 0.975 0.872,1.09 337 3368 0.4831 0.959 0.853,1.08 305 3127
573.4 Acute and subacute necrosis of liver digestive Both 0.8433 0.987 0.87,1.12 258 2580 0.9397 0.995 0.873,1.13 243 2440
573.5 Jaundice (not of newborn) digestive Both 0.5929 0.98 0.909,1.06 758 7555 0.7925 0.99 0.916,1.07 704 7181
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.05129 1.05 1.0,1.1 1973 19683 0.1236 1.04 0.99,1.09 1791 18421
573.7 Abnormal results of function study of liver digestive Both 0.7228 1.01 0.964,1.05 2110 21014 0.6902 1.01 0.963,1.06 1913 19600
573.9 Abnormal serum enzyme levels digestive Both 0.695 1.01 0.972,1.04 3345 28043 0.9016 0.998 0.961,1.04 3043 26185
574 Cholelithiasis and cholecystitis digestive Both 0.3899 1.02 0.978,1.06 2610 25589 0.1871 1.06 0.973,1.15 598 6102
574.1 Cholelithiasis digestive Both 0.4797 1.02 0.973,1.06 2391 23829 0.9397 0.996 0.901,1.1 404 4036
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.5715 1.04 0.915,1.18 260 2580 0.4406 1.05 0.923,1.2 236 2331
574.12 Cholelithiasis with other cholecystitis digestive Both 0.9572 0.997 0.906,1.1 444 4434 0.9397 0.996 0.901,1.1 404 4036
574.2 Calculus of bile duct digestive Both 0.8395 1.01 0.933,1.09 696 6939 0.526 1.03 0.947,1.11 647 6355
574.3 Cholecystitis without cholelithiasis digestive Both 0.3846 1.04 0.957,1.12 667 6662 0.1871 1.06 0.973,1.15 598 6102
575 Other biliary tract disease digestive Both 0.6486 0.989 0.943,1.04 1868 18668 0.5728 1.05 0.894,1.23 162 1722
575.1 Cholangitis digestive Both 0.7798 1.02 0.905,1.14 310 3089 0.6592 1.03 0.91,1.16 290 2925
575.2 Obstruction of bile duct digestive Both 0.9397 0.997 0.912,1.09 530 5291 0.631 1.02 0.933,1.12 494 4927
575.6 Cholesterolosis of gallbladder digestive Both 0.9162 0.992 0.849,1.16 168 1680 0.9683 1.0 0.853,1.18 151 1536
575.7 Other disorders of gallbladder digestive Both 0.5888 0.98 0.911,1.05 773 7719 0.7261 0.986 0.913,1.07 698 7018
575.8 Other disorders of biliary tract digestive Both 0.3945 0.972 0.911,1.04 996 9950 0.4989 0.977 0.913,1.05 921 9183
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.4699 1.06 0.911,1.22 188 1880 0.5728 1.05 0.894,1.23 162 1722
577 Diseases of pancreas digestive Both 0.5902 0.987 0.941,1.04 1842 18379 0.3908 0.957 0.866,1.06 419 4165
577.1 Acute pancreatitis digestive Both 0.5534 0.98 0.917,1.05 967 9651 0.7112 0.987 0.922,1.06 913 8911
577.2 Chronic pancreatitis digestive Both 0.1585 0.929 0.838,1.03 396 3955 0.4159 0.957 0.86,1.06 374 3649
577.3 Cyst and pseudocyst of pancreas digestive Both 0.4989 0.968 0.88,1.06 462 4557 0.3908 0.957 0.866,1.06 419 4165
578 Gastrointestinal hemorrhage digestive Both 0.929 0.998 0.964,1.03 3572 30460 0.8954 0.996 0.938,1.06 1168 11394
578.1 Hematemesis digestive Both 0.8222 1.01 0.911,1.12 383 3821 0.9705 1.0 0.9,1.12 364 3572
578.2 Blood in stool digestive Both 0.4498 0.983 0.941,1.03 2156 21196 0.6966 0.991 0.946,1.04 1997 19561
578.8 Hemorrhage of rectum and anus digestive Both 0.6577 1.01 0.962,1.06 1718 17070 0.6792 1.01 0.96,1.06 1582 15720
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.8318 0.994 0.937,1.05 1238 12280 0.8954 0.996 0.938,1.06 1168 11394
579 Other symptoms involving abdomen and pelvis digestive Both 0.9354 0.999 0.965,1.03 3750 28690 0.3327 1.03 0.966,1.11 917 9049
579.2 Splenomegaly digestive Both 0.1581 0.942 0.866,1.02 593 5923 0.1936 0.945 0.867,1.03 565 5593
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.3034 1.03 0.97,1.1 998 9882 0.3327 1.03 0.966,1.11 917 9049
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.05754 0.945 0.892,1.0 1264 12626 0.003162 0.825 0.726,0.937 263 2537
580.1 Glomerulonephritis genitourinary Both 0.04571 0.89 0.793,0.998 324 3228 0.6531 0.969 0.843,1.11 222 2135
580.11 Proliferative glomerulonephritis genitourinary Both 0.4688 0.931 0.766,1.13 114 1140 0.471 0.929 0.759,1.14 108 1075
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.7112 0.961 0.776,1.19 92 905 0.5715 0.939 0.755,1.17 87 860
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.6281 0.967 0.844,1.11 232 2298 0.6531 0.969 0.843,1.11 222 2135
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.2143 0.906 0.775,1.06 167 1670 0.2844 0.917 0.782,1.07 160 1580
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.5902 0.982 0.918,1.05 943 9430 0.1811 0.937 0.853,1.03 475 4633
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.7379 1.01 0.931,1.11 554 5535 0.6871 1.02 0.932,1.11 523 5170
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.1028 0.926 0.845,1.02 500 4995 0.1811 0.937 0.853,1.03 475 4633
580.4 Renal sclerosis, NOS genitourinary Both 0.00537 0.838 0.739,0.949 275 2750 0.003162 0.825 0.726,0.937 263 2537
585 Renal failure genitourinary Both 0.4645 0.989 0.961,1.02 5756 27307 0.861 0.994 0.924,1.07 799 7769
585.1 Acute renal failure genitourinary Both 0.5662 1.01 0.974,1.05 3278 22851 0.4217 1.02 0.978,1.05 3108 21131
585.2 Renal failure NOS genitourinary Both 0.7516 0.987 0.913,1.07 688 6872 0.6166 0.98 0.903,1.06 645 6372
585.3 Chronic renal failure [CKD] genitourinary Both 0.6561 0.992 0.96,1.03 4216 24655 0.06761 1.08 0.995,1.17 669 6555
585.31 Renal dialysis genitourinary Both 0.7499 1.01 0.93,1.11 543 5430 0.6353 1.02 0.935,1.12 522 5078
585.32 End stage renal disease genitourinary Both 0.4083 1.03 0.958,1.11 773 7730 0.2649 1.04 0.968,1.13 739 7227
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.4395 1.02 0.974,1.06 2272 17155 0.4406 1.02 0.973,1.07 2131 15816
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.1361 1.06 0.982,1.15 707 7038 0.06761 1.08 0.995,1.17 669 6555
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.5047 0.976 0.91,1.05 851 8381 0.861 0.994 0.924,1.07 799 7769
586 Other disorders of the kidney and ureters genitourinary Both 0.6982 0.994 0.967,1.02 6202 28774 0.2594 1.03 0.978,1.09 1474 13817
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.01479 0.858 0.758,0.97 284 2825 0.1959 1.15 0.933,1.41 104 1037
586.11 Small kidney genitourinary Both 2.188E-4 0.735 0.624,0.865 165 1642 2.754E-4 0.737 0.625,0.869 161 1520
586.12 Vesicoureteral reflux genitourinary Both 0.2547 1.12 0.921,1.36 112 1120 0.1959 1.15 0.933,1.41 104 1037
586.2 Cyst of kidney, acquired genitourinary Both 0.8892 1.0 0.945,1.07 1170 11069 0.9484 0.998 0.937,1.06 1083 10321
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.8831 1.01 0.86,1.19 148 1470 0.7674 1.03 0.867,1.21 139 1402
586.4 Stricture/obstruction of ureter genitourinary Both 0.2449 1.03 0.979,1.09 1536 14675 0.2594 1.03 0.978,1.09 1474 13817
587 Kidney replaced by transpant genitourinary Both 0.6501 1.02 0.939,1.11 612 6120 0.5 1.03 0.946,1.12 587 5761
588 Disorders resulting from impaired renal function genitourinary Both 0.8472 0.992 0.918,1.07 701 7004 0.9397 1.0 0.915,1.1 493 4809
588.1 Renal osteodystrophy genitourinary Both 0.6839 0.972 0.85,1.11 227 2267 0.6902 0.972 0.847,1.12 216 2140
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.8933 0.994 0.909,1.09 525 5241 0.9397 1.0 0.915,1.1 493 4809
589 Abnormal results of function study of kidney genitourinary Both 0.2472 0.959 0.893,1.03 840 8370 0.4753 0.974 0.905,1.05 794 7777
590 Pyelonephritis genitourinary Both 0.1811 1.04 0.981,1.11 1161 11597 0.1986 1.04 0.979,1.11 1077 10574
591 Urinary tract infection genitourinary Both 0.9572 0.999 0.974,1.03 8020 27291 0.7079 0.995 0.969,1.02 7268 25472
592 Cystitis and urethritis genitourinary Both 0.5117 0.985 0.943,1.03 2264 19423 0.1396 0.873 0.728,1.05 137 1357
592.1 Cystitis genitourinary Both 0.6966 0.991 0.948,1.04 2149 18531 0.8035 1.01 0.907,1.13 329 3144
592.11 Acute cystitis genitourinary Both 0.6501 1.01 0.957,1.07 1256 12111 0.875 1.0 0.945,1.07 1105 10771
592.12 Chronic cystitis genitourinary Both 0.8974 1.01 0.871,1.17 199 1972 0.7586 1.02 0.877,1.2 182 1731
592.13 Chronic interstitial cystitis genitourinary Both 0.7852 1.02 0.911,1.13 354 3540 0.8035 1.01 0.907,1.13 329 3144
592.2 Urethritis and urethral syndrome genitourinary Both 0.257 0.903 0.757,1.08 143 1430 0.1396 0.873 0.728,1.05 137 1357
593 Hematuria genitourinary Both 0.4539 0.987 0.954,1.02 3848 26566 0.869 1.01 0.929,1.09 646 6564
593.1 Gross hematuria genitourinary Both 0.6839 0.988 0.93,1.05 1201 11351 0.6776 0.987 0.928,1.05 1141 10755
593.2 Microscopic hematuria genitourinary Both 0.2636 1.04 0.968,1.13 724 7225 0.869 1.01 0.929,1.09 646 6564
594 Urinary calculus genitourinary Both 0.8279 1.0 0.975,1.03 5516 31876 0.8128 1.02 0.894,1.15 273 2631
594.1 Calculus of kidney genitourinary Both 0.6237 1.01 0.978,1.04 5155 31730 0.561 1.01 0.979,1.04 4905 29364
594.2 Calculus of lower urinary tract genitourinary Both 0.3639 1.05 0.94,1.18 310 3068 0.3581 1.06 0.94,1.19 305 2973
594.3 Calculus of ureter genitourinary Both 0.8072 1.01 0.947,1.07 1104 11000 0.9616 0.998 0.937,1.06 1044 10292
594.8 Renal colic genitourinary Both 0.8035 0.984 0.869,1.12 286 2851 0.8128 1.02 0.894,1.15 273 2631
595 Hydronephrosis genitourinary Both 0.6353 0.987 0.934,1.04 1410 14092 0.859 0.995 0.941,1.05 1348 13157
596 Other disorders of bladder genitourinary Both 0.7194 1.01 0.967,1.05 2527 23338 0.4603 1.02 0.965,1.08 1275 12396
596.1 Bladder neck obstruction genitourinary Both 0.3192 1.06 0.946,1.18 333 3288 0.2535 1.07 0.954,1.19 330 3222
596.5 Functional disorders of bladder genitourinary Both 0.9016 1.0 0.95,1.06 1368 13608 0.4603 1.02 0.965,1.08 1275 12396
597 Other disorders of urethra and urinary tract genitourinary Both 0.07762 1.06 0.994,1.13 1041 10322 0.3076 1.09 0.923,1.29 143 1380
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.3999 1.04 0.954,1.13 608 6024 0.2704 1.05 0.964,1.14 600 5900
597.2 Urinary complications NEC genitourinary Both 0.2825 0.963 0.898,1.03 861 8600 0.3412 0.966 0.899,1.04 823 8032
597.8 Urethral hypermobility/ISD genitourinary Both 0.3698 1.08 0.918,1.26 158 1578 0.3076 1.09 0.923,1.29 143 1380
598 Abnormal findings on examination of urine genitourinary Both 0.03388 1.06 1.0,1.13 1263 12596 0.07943 1.06 0.993,1.12 1124 11213
598.4 Other cells and casts in urine genitourinary Both 0.4335 0.918 0.742,1.14 91 906 0.1409 0.845 0.674,1.06 81 827
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.04365 1.06 1.0,1.13 1234 12317 0.07943 1.06 0.993,1.12 1124 11213
599 Other symptoms/disorders or the urinary system genitourinary Both 0.6998 0.996 0.973,1.02 11346 25364 0.4645 0.983 0.94,1.03 2171 18639
599.1 Urinary obstruction genitourinary Both 0.04467 0.915 0.839,0.998 580 5634 0.0309 0.908 0.832,0.991 569 5453
599.2 Retention of urine genitourinary Both 0.7211 0.994 0.961,1.03 4234 24058 0.9376 0.999 0.965,1.03 4045 22335
599.3 Dysuria genitourinary Both 0.6622 1.01 0.972,1.05 3426 23180 0.9376 0.998 0.961,1.04 3082 21449
599.4 Urinary incontinence genitourinary Both 0.1409 0.976 0.945,1.01 4566 22567 0.2624 0.981 0.948,1.01 4224 20833
599.5 Frequency of urination and polyuria genitourinary Both 0.9462 0.999 0.966,1.03 4277 23742 0.7534 0.995 0.961,1.03 3957 22005
599.6 Oliguria and anuria genitourinary Both 0.4169 1.04 0.948,1.14 513 5104 0.2317 1.06 0.964,1.16 481 4735
599.7 Urethral discharge genitourinary Both 0.5702 0.936 0.744,1.18 83 830 0.4645 0.918 0.728,1.16 82 820
599.8 Other symptoms involving urinary system genitourinary Both 0.7079 0.994 0.962,1.03 4366 23262 0.5559 0.99 0.957,1.02 4062 21527
599.9 Other abnormality of urination genitourinary Both 0.8299 0.995 0.953,1.04 2349 20289 0.4645 0.983 0.94,1.03 2171 18639
600 Hyperplasia of prostate genitourinary Male 0.03236 0.955 0.915,0.996 3315 9437 0.0257 0.953 0.914,0.994 3300 9404
601 Inflammatory diseases of prostate genitourinary Male 0.2223 0.956 0.89,1.03 825 7745 0.1671 0.88 0.734,1.05 124 1221
601.1 Prostatitis genitourinary Male 0.2339 0.938 0.844,1.04 378 3680 0.9354 1.01 0.799,1.28 76 752
601.11 Acute prostatitis genitourinary Male 0.1164 1.18 0.959,1.46 95 933 0.1186 1.18 0.959,1.45 95 928
601.12 Chronic prostatitis genitourinary Male 0.9638 1.01 0.794,1.27 76 757 0.9354 1.01 0.799,1.28 76 752
601.3 Orchitis and epididymitis genitourinary Male 0.7129 0.978 0.868,1.1 303 3008 0.7079 0.978 0.868,1.1 303 2999
601.4 Balanoposthitis genitourinary Male 0.6653 1.05 0.852,1.29 103 1019 0.6622 1.05 0.853,1.28 103 1016
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.1507 0.875 0.729,1.05 125 1226 0.1671 0.88 0.734,1.05 124 1221
602 Other disorders of prostate genitourinary Male 0.3715 0.944 0.832,1.07 277 2673 0.3105 0.937 0.826,1.06 276 2661
603 Other disorders of testis genitourinary Male 0.1321 0.918 0.822,1.03 348 3468 0.6607 0.96 0.802,1.15 125 1254
603.1 Hydrocele genitourinary Male 0.139 0.902 0.787,1.03 229 2281 0.1396 0.903 0.788,1.03 229 2274
603.2 Spermatocele genitourinary Male 0.5929 0.952 0.794,1.14 126 1258 0.6607 0.96 0.802,1.15 125 1254
604 Disorders of penis genitourinary Male 0.6887 1.02 0.932,1.11 536 5321 0.9886 1.0 0.858,1.17 171 1696
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.7482 1.03 0.863,1.23 130 1297 0.7534 1.03 0.863,1.23 130 1296
604.3 Peyronie's disease genitourinary Male 0.9931 0.999 0.855,1.17 171 1703 0.9886 1.0 0.858,1.17 171 1696
605 Erectile dysfunction [ED] genitourinary Male 0.5129 0.986 0.945,1.03 2844 10666 0.4416 0.984 0.943,1.03 2834 10630
608 Other disorders of male genital organs genitourinary Male 0.1563 0.959 0.905,1.02 1302 11530 0.1514 0.959 0.905,1.02 1297 11494
609 Male infertility and abnormal spermatozoa genitourinary Male 0.8531 1.01 0.904,1.13 335 3350 0.3936 1.08 0.901,1.3 119 1184
609.1 Infertility, male genitourinary Male 0.7295 0.977 0.855,1.12 242 2420 0.07079 0.809 0.643,1.02 79 787
609.11 Azoospermia and oligospermia genitourinary Male 0.07413 0.81 0.643,1.02 79 789 0.07079 0.809 0.643,1.02 79 787
609.2 Abnormal spermatozoa genitourinary Male 0.3972 1.08 0.9,1.3 119 1185 0.3936 1.08 0.901,1.3 119 1184
610 Benign mammary dysplasias genitourinary Female 1.259E-12 1.15 1.11,1.2 3089 13905 0.7762 0.988 0.91,1.07 593 9695
610.1 Cystic mastopathy genitourinary Female 3.802E-5 1.12 1.06,1.19 1361 12011 0.975 1.0 0.933,1.07 823 11478
610.4 Benign neoplasm of breast genitourinary Female 1.259E-14 1.19 1.14,1.24 2400 13828 0.3475 1.03 0.97,1.09 1228 13288
610.8 Other specified benign mammary dysplasias genitourinary Female 4.898E-5 1.14 1.07,1.22 1047 10149 0.7762 0.988 0.91,1.07 593 9695
611 Abnormal findings on mammogram or breast exam genitourinary Both 5.012E-13 1.13 1.09,1.16 4952 15509 0.5093 1.02 0.968,1.07 1815 14906
611.1 Abnormal mammogram genitourinary Both 2.512E-14 1.15 1.11,1.19 4074 13538 0.5458 1.03 0.936,1.13 445 8650
611.11 Mammographic microcalcification genitourinary Both 2.754E-8 1.21 1.13,1.29 962 9131 0.5458 1.03 0.936,1.13 445 8650
611.3 Lump or mass in breast genitourinary Both 7.943E-12 1.15 1.1,1.19 3011 15449 0.5093 1.02 0.968,1.07 1815 14906
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.05754 1.07 0.998,1.14 879 8768 0.3972 1.04 0.952,1.13 531 6523
612.1 Galactorrhea genitourinary Both 0.7962 0.975 0.807,1.18 109 1083 0.2649 0.891 0.728,1.09 95 1044
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.04074 1.08 1.0,1.17 672 6710 0.3972 1.04 0.952,1.13 531 6523
612.3 Congenital anomalies of breast genitourinary Both 0.001259 1.53 1.18,1.97 70 676 ,
613 Other nonmalignant breast conditions genitourinary Both 2.291E-9 1.12 1.08,1.17 3180 18154 0.8072 1.01 0.924,1.11 495 10907
613.1 Inflammatory disease of breast genitourinary Both 4.571E-4 1.17 1.07,1.28 504 5035 0.6194 1.03 0.905,1.18 215 4682
613.5 Mastodynia genitourinary Both 0.05012 1.06 1.0,1.12 1313 12942 0.1064 0.945 0.882,1.01 862 11975
613.7 Other signs and symptoms in breast genitourinary Both 4.365E-4 1.15 1.06,1.24 722 7109 0.2518 1.06 0.961,1.16 452 6557
613.8 Other specified disorders of breast genitourinary Both 1.202E-8 1.24 1.15,1.33 800 7961 0.6561 1.03 0.916,1.15 306 7360
613.9 Breast disorder NOS genitourinary Both 1.738E-7 1.17 1.1,1.24 1211 11947 0.8072 1.01 0.924,1.11 495 10907
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.5808 0.989 0.951,1.03 2990 16271 0.03715 0.831 0.698,0.989 146 1419
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.8892 0.991 0.875,1.12 267 2670 0.9931 1.0 0.874,1.15 224 2320
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.6053 0.974 0.88,1.08 404 4024 0.6209 0.963 0.83,1.12 188 1752
614.31 Acute inflammatory pelvic disease genitourinary Female 0.881 0.981 0.76,1.27 74 720 0.8017 0.967 0.741,1.26 72 647
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.6109 0.96 0.822,1.12 167 1666 0.7568 0.974 0.827,1.15 150 1454
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.4246 0.943 0.816,1.09 198 1979 0.6209 0.963 0.83,1.12 188 1752
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.1242 1.15 0.963,1.36 129 1290 0.177 1.13 0.945,1.36 119 1166
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.6577 0.991 0.95,1.03 2546 16112 0.03715 0.831 0.698,0.989 146 1419
614.51 Cervicitis and endocervicitis genitourinary Female 0.1276 1.12 0.969,1.29 197 1970 0.4406 1.06 0.912,1.24 173 1756
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.3289 0.978 0.935,1.02 2201 15690 0.2355 0.971 0.925,1.02 1905 13633
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.3776 1.1 0.895,1.34 104 1040 0.5 1.08 0.867,1.34 90 899
614.54 Abscess or ulceration of vulva genitourinary Female 0.01778 0.821 0.697,0.966 164 1619 0.03715 0.831 0.698,0.989 146 1419
615 Endometriosis genitourinary Female 0.5212 0.981 0.927,1.04 1298 12230 0.4634 0.977 0.919,1.04 1144 10706
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.9977 1.0 0.947,1.06 1415 13522 0.3908 0.974 0.918,1.03 1210 11878
618 Genital prolapse genitourinary Female 0.09772 0.959 0.912,1.01 1707 14626 0.006761 0.855 0.763,0.957 336 3150
618.1 Prolapse of vaginal walls genitourinary Female 0.2812 0.968 0.912,1.03 1179 11187 0.3013 0.967 0.906,1.03 1032 9431
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.6592 0.979 0.888,1.08 444 4418 0.3076 0.946 0.851,1.05 376 3723
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.4764 0.958 0.85,1.08 286 2855 0.5984 0.967 0.852,1.1 264 2364
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.009333 0.869 0.782,0.966 375 3750 0.006761 0.855 0.763,0.957 336 3150
619 Noninflammatory female genital disorders genitourinary Female 0.6095 1.01 0.976,1.04 4598 15534 0.3631 0.967 0.898,1.04 787 7924
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.2084 0.963 0.909,1.02 1262 11294 0.1358 0.953 0.895,1.02 1083 9996
619.2 Disorders of uterus, NEC genitourinary Female 0.7621 0.985 0.894,1.09 444 4435 0.3855 0.953 0.855,1.06 358 3893
619.3 Noninflammatory disorders of cervix genitourinary Female 0.877 0.992 0.895,1.1 391 3892 0.6622 0.976 0.874,1.09 341 3447
619.4 Noninflammatory disorders of vagina genitourinary Female 0.8851 0.996 0.95,1.05 1903 15019 0.2113 0.967 0.918,1.02 1602 13141
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.5105 0.978 0.914,1.05 914 9082 0.3631 0.967 0.898,1.04 787 7924
620 Dysplasia of female genital organs genitourinary Female 0.4074 0.954 0.852,1.07 325 3234 0.7396 1.03 0.857,1.24 132 1284
620.1 Dysplasia of cervix genitourinary Female 0.875 1.01 0.85,1.21 142 1420 0.7396 1.03 0.857,1.24 132 1284
621 Endometrial hyperplasia genitourinary Female 0.4325 0.956 0.856,1.07 334 3335 0.2588 0.932 0.825,1.05 286 2819
622 Polyp of female genital organs genitourinary Female 0.0871 1.05 0.992,1.12 1191 11723 0.875 0.99 0.877,1.12 288 2960
622.1 Polyp of corpus uteri genitourinary Female 0.1256 1.05 0.986,1.13 949 9362 0.4093 1.03 0.958,1.11 784 8016
622.2 Mucous polyp of cervix genitourinary Female 0.4036 1.05 0.939,1.17 348 3480 0.875 0.99 0.877,1.12 288 2960
623 Hypertrophy of female genital organs genitourinary Female 0.7482 0.986 0.907,1.07 605 6003 0.2754 0.951 0.868,1.04 513 5203
624 Symptoms involving female genital tract genitourinary Female 0.8531 0.994 0.932,1.06 1013 9695 0.5445 0.983 0.929,1.04 1370 11196
624.1 Dystrophy of female genital tract genitourinary Female 0.5321 1.05 0.898,1.23 168 1680 0.9506 0.995 0.837,1.18 143 1431
624.9 stress incontinence, female genitourinary Female 0.4634 0.981 0.93,1.03 1549 12918 0.5445 0.983 0.929,1.04 1370 11196
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.7328 1.01 0.973,1.04 4618 14394 0.2944 0.963 0.896,1.03 833 8940
625.1 Dyspareunia genitourinary Female 0.6368 1.02 0.952,1.08 1011 10081 0.2944 0.963 0.896,1.03 833 8940
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.5297 1.01 0.977,1.05 4726 13065 0.9795 0.999 0.915,1.09 570 4784
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.8453 1.0 0.966,1.04 3426 12112 0.7345 0.979 0.865,1.11 268 2801
626.11 Absent or infrequent menstruation genitourinary Female 0.561 1.02 0.95,1.1 802 6948 0.867 1.01 0.931,1.09 715 6380
626.12 Excessive or frequent menstruation genitourinary Female 0.3499 1.02 0.973,1.08 1703 9843 0.6653 1.01 0.958,1.07 1527 8850
626.13 Irregular menstrual cycle genitourinary Female 0.3776 1.02 0.971,1.08 1543 10197 0.6152 1.01 0.958,1.08 1354 9157
626.14 Irregular menstrual bleeding genitourinary Female 0.7278 0.987 0.917,1.06 777 7408 0.4457 0.97 0.897,1.05 688 6692
626.15 Infertility, female, associated with anovulation genitourinary Female 0.7603 0.982 0.873,1.1 300 3000 0.7345 0.979 0.865,1.11 268 2801
626.2 Dysmenorrhea genitourinary Female 0.9683 0.999 0.938,1.06 1116 8297 0.6902 0.987 0.924,1.05 1023 7515
626.4 Premenstrual tension syndromes genitourinary Female 0.2716 1.07 0.948,1.21 275 2741 0.4634 1.05 0.922,1.19 244 2462
626.8 Infertility, female genitourinary Female 0.8318 0.991 0.912,1.08 630 5218 0.9795 0.999 0.915,1.09 570 4784
627 Menopausal and postmenopausal disorders genitourinary Female 0.02754 1.04 1.0,1.08 3657 12296 0.3499 1.08 0.917,1.28 135 2122
627.1 Postmenopausal bleeding genitourinary Female 0.2692 1.04 0.971,1.11 957 8768 0.2535 0.956 0.886,1.03 728 7495
627.2 Symptomatic menopause genitourinary Female 0.01349 1.06 1.01,1.1 2443 11667 0.6776 1.03 0.904,1.17 258 2510
627.21 Symptomatic artificial menopause genitourinary Female 0.1455 1.14 0.955,1.37 125 1241 0.7447 0.965 0.781,1.19 90 1092
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.9863 1.0 0.889,1.13 295 2948 0.6776 1.03 0.904,1.17 258 2510
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.3573 1.04 0.96,1.12 729 7262 0.8414 1.01 0.927,1.1 599 6191
627.4 Premenopausal menorrhagia genitourinary Female 0.7674 1.02 0.904,1.15 305 3020 0.8414 1.01 0.89,1.15 259 2665
627.5 Premature menopause and other ovarian failure genitourinary Female 0.00309 1.22 1.07,1.39 234 2340 0.3499 1.08 0.917,1.28 135 2122
628 Ovarian cyst genitourinary Female 0.8954 0.996 0.946,1.05 1619 11554 0.537 0.982 0.928,1.04 1377 10282
634 Miscarriage; stillbirth pregnancy complications Female 0.5272 0.974 0.899,1.06 648 6413 0.7379 1.04 0.832,1.3 84 858
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.7047 0.974 0.848,1.12 209 2090 0.9099 0.992 0.859,1.15 193 1896
634.3 Ectopic pregnancy pregnancy complications Female 0.7603 1.03 0.838,1.27 95 950 0.7379 1.04 0.832,1.3 84 858
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.8551 1.01 0.913,1.12 414 4070 0.5728 0.96 0.834,1.11 200 1938
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.6699 1.03 0.908,1.16 272 2720 0.7568 1.02 0.897,1.16 251 2520
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.6081 0.964 0.839,1.11 206 2060 0.5728 0.96 0.834,1.11 200 1938
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.7228 0.987 0.919,1.06 855 6402 0.2636 0.861 0.662,1.12 57 555
636.1 Threatened premature labor pregnancy complications Female 0.4819 1.04 0.928,1.17 298 2980 0.3048 1.06 0.944,1.2 281 2799
636.2 Early onset of delivery pregnancy complications Female 0.2148 0.919 0.805,1.05 233 2330 0.3296 0.934 0.815,1.07 217 2164
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.3443 0.949 0.851,1.06 356 3556 0.7586 0.983 0.879,1.1 333 3287
636.8 Cervical incompetence pregnancy complications Female 0.1905 0.84 0.647,1.09 60 600 0.2636 0.861 0.662,1.12 57 555
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.2871 0.888 0.713,1.11 89 884 0.05012 0.791 0.626,1.0 78 825
638 Other high-risk pregnancy pregnancy complications Female 0.2938 0.961 0.893,1.03 818 5867 0.3784 0.967 0.897,1.04 779 5403
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.1349 0.926 0.838,1.02 421 4210 0.9311 0.993 0.856,1.15 194 1973
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.9247 0.993 0.861,1.15 215 2150 0.9311 0.993 0.856,1.15 194 1973
643 Excessive vomiting in pregnancy pregnancy complications Female 0.1233 0.885 0.758,1.03 181 1810 0.1026 0.827 0.659,1.04 79 812
643.1 Hyperemesis gravidarum pregnancy complications Female 0.02818 0.782 0.628,0.974 87 870 0.1026 0.827 0.659,1.04 79 812
644 Anemia during pregnancy pregnancy complications Female 0.6668 1.04 0.881,1.22 154 1540 0.492 1.06 0.9,1.25 150 1451
645 Late pregnancy and failed induction pregnancy complications Female 0.7998 1.02 0.901,1.15 286 2860 0.9772 1.0 0.884,1.13 263 2681
646 Other complications of pregnancy NEC pregnancy complications Female 0.8091 1.01 0.93,1.1 622 5063 1.0 1.0 0.918,1.09 591 4717
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.6081 1.04 0.888,1.23 152 1520 0.8299 1.02 0.873,1.18 175 1731
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.879 0.988 0.851,1.15 182 1820 0.8299 1.02 0.873,1.18 175 1731
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.8453 1.01 0.941,1.08 968 6387 0.3819 1.05 0.945,1.16 386 3742
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.3162 1.05 0.952,1.16 413 4130 0.3819 1.05 0.945,1.16 386 3742
650 Normal delivery pregnancy complications Female 0.8492 0.993 0.921,1.07 757 6412 0.8892 0.995 0.92,1.08 701 5905
651 Multiple gestation pregnancy complications Female 0.9099 0.988 0.804,1.21 100 1000 0.9506 0.993 0.806,1.22 94 912
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.208 0.941 0.855,1.03 461 4586 0.3639 0.956 0.866,1.05 431 4209
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.2399 0.943 0.855,1.04 443 4189 0.4875 0.965 0.873,1.07 417 3922
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.1879 0.94 0.856,1.03 482 4820 0.3999 0.933 0.795,1.1 153 1516
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.4592 0.962 0.87,1.07 402 4020 0.4603 0.961 0.865,1.07 375 3696
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.4009 0.935 0.801,1.09 163 1630 0.3999 0.933 0.795,1.1 153 1516
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.3483 0.972 0.915,1.03 1244 8117 0.3945 0.958 0.867,1.06 427 4094
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.3048 0.95 0.862,1.05 451 4371 0.3945 0.958 0.867,1.06 427 4094
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.05012 1.14 1.0,1.3 246 2460 0.2523 1.17 0.894,1.53 55 544
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.241 1.17 0.902,1.51 59 590 0.2523 1.17 0.894,1.53 55 544
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.4093 0.94 0.812,1.09 195 1950 0.3206 0.923 0.788,1.08 169 1765
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.1466 1.07 0.977,1.17 504 4732 0.06166 1.09 0.996,1.2 476 4396
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.9727 1.0 0.906,1.11 420 4080 0.778 1.01 0.916,1.12 394 3809
665 Obstetrical/birth trauma pregnancy complications Female 0.6668 0.984 0.912,1.06 751 6161 0.5559 0.977 0.903,1.06 694 5666
669 Complications of labor and delivery NEC pregnancy complications Female 0.7396 0.986 0.909,1.07 671 5265 0.7621 0.987 0.908,1.07 635 4890
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.2564 1.09 0.937,1.28 172 1720 0.2466 1.1 0.936,1.3 153 1540
674 Other complications of the puerperium NEC pregnancy complications Female 0.9057 0.991 0.852,1.15 181 1810 0.8147 0.982 0.84,1.15 173 1673
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.9419 0.993 0.83,1.19 122 1220 0.7907 0.975 0.811,1.17 113 1146
681 Superficial cellulitis and abscess dermatologic Both 0.1062 1.02 0.995,1.06 5078 31991 0.7516 1.01 0.95,1.07 1093 11440
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.6683 1.02 0.948,1.09 862 8581 0.7345 1.01 0.942,1.09 785 7950
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.3027 1.04 0.966,1.12 781 7775 0.2339 1.05 0.971,1.13 716 7230
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.1189 0.959 0.91,1.01 1533 15238 0.1064 0.956 0.905,1.01 1395 14221
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.2153 0.969 0.921,1.02 1649 16359 0.2213 0.968 0.918,1.02 1513 15272
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.271 0.968 0.914,1.03 1291 12850 0.2773 0.967 0.911,1.03 1178 12001
681.7 Cellulitis and abscess of trunk dermatologic Both 0.5483 1.02 0.96,1.08 1238 12342 0.7516 1.01 0.95,1.07 1093 11440
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.4169 1.02 0.971,1.07 1660 16466 0.3758 1.09 0.901,1.32 114 1112
686.1 Carbuncle and furuncle dermatologic Both 0.5023 1.04 0.935,1.15 390 3881 0.8831 1.01 0.899,1.13 308 3581
686.2 Impetigo dermatologic Both 0.3141 1.06 0.945,1.19 310 3068 0.3148 1.07 0.941,1.21 272 2841
686.3 Pilonidal cyst dermatologic Both 0.5236 0.942 0.785,1.13 120 1200 0.5333 0.943 0.783,1.14 116 1144
686.4 Pyogenic granuloma dermatologic Both 0.5058 1.07 0.885,1.28 121 1205 0.3758 1.09 0.901,1.32 114 1112
687 Symptoms affecting skin dermatologic Both 0.4395 0.989 0.962,1.02 6119 25901 0.1816 0.979 0.948,1.01 4572 24033
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.7379 0.995 0.966,1.02 5371 25824 0.4375 0.988 0.957,1.02 4784 24272
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.9572 0.999 0.97,1.03 5264 25870 0.3864 0.986 0.956,1.02 4679 24318
687.3 Changes in skin texture dermatologic Both 0.2541 0.933 0.829,1.05 294 2926 0.3664 0.943 0.83,1.07 253 2724
687.4 Disturbance of skin sensation dermatologic Both 0.1309 0.977 0.947,1.01 4942 25586 0.1816 0.979 0.948,1.01 4572 24033
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.3311 1.01 0.987,1.04 7192 31086 0.8472 1.0 0.976,1.03 6408 29176
690 Erythematosquamous dermatosis dermatologic Both 0.4457 0.987 0.954,1.02 3810 26256 0.1219 0.972 0.937,1.01 3395 24339
690.1 Seborrheic dermatitis dermatologic Both 0.4315 0.986 0.953,1.02 3802 26218 0.1219 0.972 0.937,1.01 3395 24339
691 Congenital anomalies of skin dermatologic Both 0.1117 0.92 0.83,1.02 411 4110 0.1045 0.914 0.82,1.02 370 3786
694 Dyschromia and Vitiligo dermatologic Both 0.561 1.02 0.96,1.08 1286 12819 0.5998 0.935 0.729,1.2 59 643
694.1 Vitiligo dermatologic Both 0.5808 1.06 0.862,1.3 94 931 0.8872 1.02 0.813,1.27 81 844
694.2 Other dyschromia dermatologic Both 0.6152 1.02 0.956,1.08 1146 11421 0.7311 0.989 0.927,1.05 1019 10352
694.3 Vascular disorders of skin dermatologic Both 0.9204 1.01 0.802,1.28 69 686 0.5998 0.935 0.729,1.2 59 643
695 Erythematous conditions dermatologic Both 0.7727 1.01 0.969,1.04 3180 24642 0.4159 0.959 0.868,1.06 409 4657
695.2 Bullous dermatoses dermatologic Both 0.5728 0.929 0.719,1.2 68 658 0.8204 0.97 0.747,1.26 65 608
695.3 Rosacea dermatologic Both 0.7816 1.01 0.954,1.06 1405 14019 0.873 1.0 0.948,1.06 1234 12635
695.4 Lupus (localized and systemic) dermatologic Both 0.4395 0.966 0.885,1.05 556 5556 0.5458 0.972 0.885,1.07 491 4693
695.41 Cutaneous lupus erythematosus dermatologic Both 0.3972 0.938 0.809,1.09 196 1955 0.2642 0.914 0.781,1.07 178 1740
695.42 Systemic lupus erythematosus dermatologic Both 0.2851 0.952 0.871,1.04 530 5287 0.5458 0.972 0.885,1.07 491 4693
695.7 Prurigo and Lichen dermatologic Both 0.06918 1.1 0.993,1.21 429 4275 0.08318 1.1 0.988,1.22 374 3846
695.8 Other specified erythematous conditions dermatologic Both 0.6592 1.02 0.938,1.11 613 6111 0.8166 1.01 0.924,1.11 518 5454
695.9 Unspecified erythematous condition dermatologic Both 0.9638 1.0 0.916,1.1 513 5102 0.4159 0.959 0.868,1.06 409 4657
696 Psoriasis and related disorders dermatologic Both 0.9886 1.0 0.939,1.06 1080 10781 0.3565 1.07 0.928,1.23 209 2096
696.3 Pityriasis dermatologic Both 0.005495 0.693 0.535,0.898 64 640 0.01259 0.706 0.537,0.928 59 592
696.4 Psoriasis dermatologic Both 0.597 1.02 0.954,1.09 1014 10115 0.3565 1.07 0.928,1.23 209 2096
696.41 Psoriasis vulgaris dermatologic Both 0.7691 1.01 0.944,1.08 918 9161 0.6823 1.01 0.946,1.09 845 8500
696.42 Psoriatic arthropathy dermatologic Both 0.3475 1.07 0.931,1.22 225 2250 0.3565 1.07 0.928,1.23 209 2096
697 Sarcoidosis dermatologic Both 0.3499 1.06 0.936,1.21 265 2650 0.3784 1.06 0.931,1.21 245 2443
698 Pruritus and related conditions dermatologic Both 0.07244 0.956 0.909,1.0 1686 16680 0.2056 0.966 0.917,1.02 1490 14976
700 Corns and callosities dermatologic Both 0.5649 0.978 0.908,1.05 764 7615 0.7379 0.987 0.912,1.07 690 7000
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.1211 0.978 0.951,1.01 5838 31889 0.7194 1.02 0.909,1.15 300 3038
701.1 Keratoderma, acquired dermatologic Both 0.7586 0.984 0.885,1.09 389 3845 0.4699 0.959 0.855,1.08 331 3487
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.743 0.992 0.944,1.04 1705 16953 0.1459 0.96 0.909,1.01 1404 15552
701.3 Circumscribed scleroderma dermatologic Both 0.3784 1.04 0.948,1.15 434 4334 0.811 1.01 0.911,1.13 374 3819
701.4 Keloid scar dermatologic Both 0.6383 1.02 0.93,1.13 454 4503 0.2992 1.06 0.953,1.17 386 4155
701.5 Abnormal granulation tissue dermatologic Both 0.6577 1.03 0.917,1.15 328 3260 0.7194 1.02 0.909,1.15 300 3038
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.7674 0.995 0.966,1.03 5351 24908 0.3681 0.878 0.662,1.17 53 572
702.1 Actinic keratosis dermatologic Both 0.3828 1.02 0.979,1.06 3236 22206 0.5781 1.01 0.972,1.05 2954 20472
702.2 Seborrheic keratosis dermatologic Both 0.4624 0.988 0.956,1.02 4151 26248 0.1076 0.972 0.938,1.01 3671 24227
702.4 Degenerative skin disorders dermatologic Both 0.9863 0.998 0.768,1.3 63 624 0.3681 0.878 0.662,1.17 53 572
703 Diseases of nail, NOS dermatologic Both 0.3388 1.03 0.968,1.1 1033 10222 0.4487 1.04 0.947,1.13 524 5334
703.1 Ingrowing nail dermatologic Both 0.2716 1.05 0.963,1.14 580 5773 0.4487 1.04 0.947,1.13 524 5334
704 Diseases of hair and hair follicles dermatologic Both 0.3793 0.981 0.94,1.02 2321 22718 0.06761 0.946 0.891,1.0 1199 11949
704.1 Alopecia dermatologic Both 0.4027 1.03 0.965,1.09 1074 10601 0.369 0.968 0.901,1.04 809 9375
704.11 Alopecia Areata dermatologic Both 0.6546 0.942 0.726,1.22 58 580 ,
704.2 Hirsutism dermatologic Both 0.3837 1.06 0.929,1.21 227 2263 0.1991 1.1 0.953,1.26 203 2065
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.02692 0.937 0.885,0.993 1286 12791 0.06761 0.946 0.891,1.0 1199 11949
705 Disorders of sweat glands dermatologic Both 0.6397 1.02 0.928,1.13 439 4376 0.9183 0.996 0.925,1.07 773 7745
705.1 Dyshidrosis dermatologic Both 0.1167 0.856 0.704,1.04 114 1131 0.1875 0.875 0.717,1.07 107 1042
705.3 Hidradenitis dermatologic Both 0.9226 1.01 0.867,1.17 183 1815 0.912 0.991 0.847,1.16 168 1685
705.8 Hyperhidrosis dermatologic Both 0.8551 1.01 0.938,1.08 846 8429 0.9183 0.996 0.925,1.07 773 7745
706 Diseases of sebaceous glands dermatologic Both 0.6934 0.994 0.963,1.03 4454 32859 0.3192 1.03 0.969,1.1 1002 10224
706.1 Acne dermatologic Both 0.4831 1.02 0.97,1.07 1931 17499 0.5248 1.02 0.967,1.07 1783 16218
706.2 Sebaceous cyst dermatologic Both 0.2698 0.975 0.933,1.02 2150 21106 0.1178 0.963 0.919,1.01 1915 19450
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.2799 1.03 0.973,1.1 1124 11122 0.3192 1.03 0.969,1.1 1002 10224
707 Chronic ulcer of skin dermatologic Both 0.1309 1.03 0.99,1.08 2193 21811 0.3311 1.03 0.971,1.09 1203 12192
707.1 Decubitus ulcer dermatologic Both 0.9016 1.01 0.925,1.09 600 5984 0.863 1.01 0.926,1.1 575 5584
707.2 Chronic ulcer of leg or foot dermatologic Both 0.1262 1.06 0.983,1.14 721 7166 0.05623 1.08 0.998,1.17 680 6724
707.3 Chronic ulcer of unspecified site dermatologic Both 0.3648 1.03 0.97,1.09 1339 13370 0.3311 1.03 0.971,1.09 1203 12192
709 Diffuse diseases of connective tissue dermatologic Both 0.3373 0.97 0.911,1.03 1086 10825 0.5598 0.975 0.896,1.06 592 5865
709.2 Sicca syndrome dermatologic Both 0.778 1.02 0.911,1.13 365 3650 0.7413 1.02 0.908,1.14 321 3194
709.3 Systemic sclerosis dermatologic Both 0.06166 0.868 0.749,1.01 184 1840 0.08913 0.876 0.752,1.02 172 1661
709.5 Dermatomyositis dermatologic Both 0.5768 0.935 0.738,1.18 70 700 0.3648 0.892 0.697,1.14 66 644
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.8954 0.985 0.782,1.24 78 780 0.9817 0.997 0.788,1.26 75 709
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.4325 0.968 0.894,1.05 659 6563 0.5598 0.975 0.896,1.06 592 5865
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.7709 0.996 0.966,1.03 5120 27320 0.1002 0.797 0.608,1.04 59 561
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.2455 0.86 0.667,1.11 64 626 0.1002 0.797 0.608,1.04 59 561
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.3451 1.03 0.966,1.1 954 9524 0.208 1.05 0.975,1.12 823 8137
710.1 Osteomyelitis musculoskeletal Both 0.3606 1.03 0.964,1.1 914 9127 0.208 1.05 0.975,1.12 823 8137
710.11 Acute osteomyelitis musculoskeletal Both 0.0537 1.1 0.999,1.22 425 4234 0.07244 1.1 0.991,1.22 408 4011
710.12 Chronic osteomyelitis musculoskeletal Both 0.3811 1.05 0.943,1.16 378 3758 0.4699 1.04 0.935,1.16 365 3570
710.19 Unspecified osteomyelitis musculoskeletal Both 0.3083 1.04 0.967,1.11 867 8656 0.208 1.05 0.975,1.12 823 8137
711 Arthropathy associated with infections musculoskeletal Both 0.2275 0.931 0.83,1.05 314 3124 0.1687 0.907 0.79,1.04 216 2092
711.1 Pyogenic arthritis musculoskeletal Both 0.25 0.923 0.805,1.06 223 2206 0.1687 0.907 0.79,1.04 216 2092
712 Infective connective tissue disorders musculoskeletal Both 0.9616 0.996 0.837,1.18 136 1360 0.826 0.98 0.818,1.17 127 1275
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.1503 1.11 0.964,1.27 222 2214 0.138 1.16 0.953,1.42 107 1104
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.2917 1.1 0.918,1.33 118 1180 0.138 1.16 0.953,1.42 107 1104
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.3483 1.02 0.974,1.08 1649 14662 0.01778 1.07 1.01,1.14 1230 11040
714.1 Rheumatoid arthritis musculoskeletal Both 0.1 1.05 0.991,1.11 1342 12332 0.01778 1.07 1.01,1.14 1230 11040
715 Other inflammatory spondylopathies musculoskeletal Both 0.7145 0.988 0.925,1.05 979 9761 0.9376 0.994 0.854,1.16 169 1615
715.1 Sacroiliitis NEC musculoskeletal Both 0.695 0.972 0.844,1.12 212 2120 0.9462 0.995 0.859,1.15 194 1906
715.2 Ankylosing spondylitis musculoskeletal Both 0.7907 0.98 0.845,1.14 177 1760 0.9376 0.994 0.854,1.16 169 1615
716 Other arthropathies musculoskeletal Both 0.413 1.01 0.987,1.03 10893 26011 0.5433 1.01 0.983,1.03 9861 24358
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.5309 0.95 0.808,1.12 155 1540 0.507 0.945 0.798,1.12 144 1403
716.2 Unspecified monoarthritis musculoskeletal Both 0.2692 1.11 0.923,1.33 116 1156 0.2523 1.12 0.925,1.35 112 1062
716.9 Arthropathy NOS musculoskeletal Both 0.4819 1.01 0.985,1.03 10831 26002 0.5433 1.01 0.983,1.03 9861 24358
717 Polymyalgia Rheumatica musculoskeletal Both 0.5224 1.05 0.908,1.21 210 2061 0.6871 1.03 0.887,1.2 192 1815
720 Spinal stenosis musculoskeletal Both 0.9908 1.0 0.964,1.04 3298 24117 0.9462 1.0 0.958,1.05 2259 18878
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.9638 1.0 0.959,1.04 2415 20454 0.9462 1.0 0.958,1.05 2259 18878
721 Spondylosis and allied disorders musculoskeletal Both 0.8337 0.997 0.965,1.03 4494 27007 0.9705 1.0 0.869,1.16 203 1936
721.1 Spondylosis without myelopathy musculoskeletal Both 0.9057 0.998 0.966,1.03 4206 26584 0.912 0.998 0.965,1.03 3875 24614
721.2 Spondylosis with myelopathy musculoskeletal Both 0.8872 0.995 0.922,1.07 740 7398 0.9594 1.0 0.927,1.08 706 6837
721.8 Other allied disorders of spine musculoskeletal Both 0.859 1.01 0.88,1.17 212 2099 0.9705 1.0 0.869,1.16 203 1936
722 Intervertebral disc disorders musculoskeletal Both 0.241 1.02 0.988,1.05 5242 28702 0.4581 0.98 0.929,1.03 1483 14490
722.1 Displacement of intervertebral disc musculoskeletal Both 0.1503 1.03 0.99,1.07 3038 26827 0.2455 1.02 0.984,1.06 2808 24859
722.3 Schmorl's nodes musculoskeletal Both 0.778 0.974 0.808,1.17 115 1140 0.9572 1.01 0.829,1.22 107 1089
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.673 1.01 0.972,1.04 3338 26140 0.865 1.0 0.966,1.04 3081 24201
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.4932 1.03 0.94,1.14 464 4634 0.2455 1.06 0.961,1.17 443 4274
722.8 Postlaminectomy syndrome musculoskeletal Both 0.5768 0.968 0.863,1.09 336 3360 0.5012 0.96 0.853,1.08 318 3073
722.9 Other and unspecified disc disorder musculoskeletal Both 0.4315 0.979 0.93,1.03 1569 15676 0.4581 0.98 0.929,1.03 1483 14490
723 Other disorders of cervical region musculoskeletal Both 0.006761 0.901 0.836,0.972 761 7610 0.3243 0.924 0.79,1.08 172 1746
723.1 Torticollis musculoskeletal Both 0.2812 0.92 0.79,1.07 187 1870 0.3243 0.924 0.79,1.08 172 1746
724 Other and unspecified disorders of back musculoskeletal Both 0.9419 1.0 0.966,1.04 3338 26730 0.4498 1.02 0.964,1.09 1175 11420
724.1 Disorders of sacrum musculoskeletal Both 0.9616 0.999 0.952,1.05 1804 17663 0.6053 0.987 0.937,1.04 1621 15877
724.2 Disorders of coccyx musculoskeletal Both 0.02951 0.884 0.791,0.988 331 3290 0.03311 0.882 0.786,0.99 305 2974
724.8 Other symptoms referable to back musculoskeletal Both 0.3365 0.964 0.895,1.04 753 7499 0.5957 0.979 0.906,1.06 699 6860
724.9 Other unspecified back disorders musculoskeletal Both 0.6982 1.01 0.955,1.07 1246 12418 0.4498 1.02 0.964,1.09 1175 11420
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.9226 0.999 0.973,1.02 7682 25455 0.537 0.978 0.911,1.05 817 8094
726.1 Enthesopathy musculoskeletal Both 0.4519 0.989 0.961,1.02 5795 25454 0.4634 0.989 0.96,1.02 5303 23859
726.2 Synoviopathy musculoskeletal Both 0.9016 1.0 0.934,1.08 774 7723 0.9817 0.999 0.927,1.08 731 7148
726.3 Bursitis musculoskeletal Both 0.2094 0.965 0.913,1.02 1339 13090 0.4064 0.976 0.921,1.03 1224 12094
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.3715 0.969 0.906,1.04 889 8846 0.537 0.978 0.911,1.05 817 8094
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.1622 0.98 0.952,1.01 5811 25457 0.0389 0.815 0.671,0.99 113 1082
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.1067 0.965 0.925,1.01 2342 20541 0.1452 0.967 0.924,1.01 2113 18990
727.2 Bursitis disorders musculoskeletal Both 0.3715 0.951 0.851,1.06 341 3381 0.3758 0.949 0.846,1.07 313 3096
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.2388 1.04 0.976,1.1 1109 11034 0.2838 1.04 0.971,1.1 1007 10038
727.5 Rupture of synovium musculoskeletal Both 0.2825 0.944 0.849,1.05 376 3718 0.2958 0.942 0.843,1.05 341 3369
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.3192 0.976 0.932,1.02 1927 18092 0.3499 0.977 0.931,1.03 1802 16861
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.6324 0.978 0.894,1.07 520 5187 0.9616 0.998 0.909,1.09 480 4772
727.8 Plica syndrome musculoskeletal Both 0.0302 0.807 0.664,0.979 115 1117 0.0389 0.815 0.671,0.99 113 1082
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.6607 0.992 0.957,1.03 3433 24951 0.631 0.971 0.861,1.1 286 2900
728.1 Muscular calcification and ossification musculoskeletal Both 0.861 0.979 0.77,1.24 69 682 0.9954 0.999 0.783,1.28 67 646
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.5483 0.959 0.837,1.1 230 2298 0.8279 0.984 0.855,1.13 213 2142
728.7 Fasciitis musculoskeletal Both 0.6081 0.988 0.944,1.03 2056 19042 0.631 0.971 0.861,1.1 286 2900
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.7362 0.98 0.873,1.1 310 3095 0.631 0.971 0.861,1.1 286 2900
729 Other disorders of soft tissues musculoskeletal Both 0.7943 1.01 0.966,1.05 2618 22751 0.5358 0.919 0.704,1.2 51 513
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.9977 1.0 0.784,1.28 63 630 0.9141 1.01 0.783,1.31 58 569
729.3 Panniculitis musculoskeletal Both 0.4093 0.919 0.751,1.12 100 1000 0.2793 0.891 0.723,1.1 94 904
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.7551 0.959 0.739,1.25 53 530 0.5358 0.919 0.704,1.2 51 513
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.4467 1.07 0.9,1.27 145 1441 0.5546 1.06 0.883,1.26 134 1373
732 Osteochondropathies musculoskeletal Both 0.1377 0.914 0.811,1.03 289 2882 0.8472 1.02 0.807,1.3 69 682
732.1 Juvenile osteochondrosis musculoskeletal Both 0.3076 0.919 0.781,1.08 157 1570 0.6516 0.962 0.813,1.14 146 1496
732.7 Osteochondritis dissecans musculoskeletal Both 0.6501 0.948 0.75,1.2 71 710 0.8472 1.02 0.807,1.3 69 682
733 Other disorders of bone and cartilage musculoskeletal Both 0.3715 1.02 0.981,1.05 3481 21966 0.6067 0.941 0.746,1.19 77 766
733.2 Cyst of bone musculoskeletal Both 0.354 0.926 0.788,1.09 162 1613 0.5093 0.946 0.801,1.12 154 1484
733.4 Aseptic necrosis of bone musculoskeletal Both 0.7161 1.02 0.92,1.13 405 4042 0.9705 1.0 0.902,1.11 377 3791
733.6 Costochondritis musculoskeletal Both 0.695 0.976 0.862,1.1 275 2742 0.3199 0.935 0.818,1.07 242 2492
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.3648 1.04 0.959,1.12 701 7003 0.3373 1.04 0.96,1.13 671 6585
733.9 Chondromalacia musculoskeletal Both 0.5888 0.939 0.746,1.18 80 800 0.6067 0.941 0.746,1.19 77 766
735 Acquired foot deformities musculoskeletal Both 0.5821 0.988 0.948,1.03 2431 23304 0.02512 0.926 0.866,0.991 920 9213
735.1 Flat foot musculoskeletal Both 0.6607 1.02 0.927,1.13 437 4355 0.5875 1.03 0.928,1.14 396 3979
735.2 Acquired toe deformities musculoskeletal Both 0.2153 0.957 0.894,1.03 869 8616 0.9727 1.0 0.885,1.13 269 2668
735.21 Hammer toe (acquired) musculoskeletal Both 0.1125 0.93 0.85,1.02 509 5041 0.05495 0.91 0.827,1.0 446 4508
735.23 Hallux rigidus musculoskeletal Both 0.7112 0.978 0.871,1.1 299 2975 0.9727 1.0 0.885,1.13 269 2668
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.02818 0.932 0.874,0.992 1039 10308 0.02512 0.926 0.866,0.991 920 9213
736 Other acquired deformities of limbs musculoskeletal Both 0.863 0.996 0.951,1.04 1997 19771 0.492 1.05 0.918,1.19 232 2299
736.1 Acquired deformities of forearm musculoskeletal Both 0.7798 1.03 0.84,1.26 90 892 0.7834 1.03 0.838,1.26 87 831
736.2 Acquired deformities of finger musculoskeletal Both 0.07244 0.868 0.744,1.01 169 1684 0.05623 0.856 0.73,1.0 160 1554
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.3228 1.07 0.937,1.22 239 2382 0.5 1.05 0.914,1.2 224 2197
736.5 Acquired deformities of knee musculoskeletal Both 0.08128 1.14 0.984,1.32 184 1834 0.1213 1.13 0.968,1.32 169 1717
736.6 Unequal leg length (acquired) musculoskeletal Both 0.7047 1.02 0.904,1.16 256 2555 0.492 1.05 0.918,1.19 232 2299
737 Curvature of spine musculoskeletal Both 0.6607 0.987 0.932,1.05 1268 12573 0.5888 1.02 0.952,1.09 920 8839
737.1 Kyphosis (acquired) musculoskeletal Both 0.2523 1.06 0.958,1.18 383 3819 0.1782 1.08 0.967,1.2 356 3474
737.2 Lordosis (acquired) musculoskeletal Both 0.2965 1.14 0.893,1.45 65 650 0.2168 1.17 0.912,1.5 62 572
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.9162 0.996 0.933,1.06 987 9782 0.5888 1.02 0.952,1.09 920 8839
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.5212 1.02 0.969,1.06 1968 19555 0.2307 1.05 0.972,1.12 800 7817
738.4 Acquired spondylolisthesis musculoskeletal Both 0.7112 1.01 0.945,1.09 863 8617 0.2307 1.05 0.972,1.12 800 7817
739 Contracture of joint musculoskeletal Both 0.1127 0.93 0.85,1.02 522 5203 0.2466 0.946 0.862,1.04 484 4772
740 Osteoarthrosis musculoskeletal Both 0.7345 1.0 0.982,1.03 13133 25195 0.7745 1.0 0.98,1.03 11522 23550
740.1 Osteoarthritis; localized musculoskeletal Both 0.2636 0.983 0.953,1.01 5329 22764 0.4955 0.969 0.883,1.06 487 4773
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.1592 0.977 0.945,1.01 4543 21500 0.09772 0.972 0.939,1.01 4143 20031
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.3954 0.962 0.88,1.05 514 5125 0.4955 0.969 0.883,1.06 487 4773
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.6339 0.986 0.93,1.05 1266 9917 0.9863 0.999 0.94,1.06 1129 8968
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.6531 0.973 0.866,1.09 303 2974 0.8851 0.991 0.877,1.12 279 2657
740.9 Osteoarthrosis NOS musculoskeletal Both 0.7925 1.0 0.981,1.03 12648 25075 0.7745 1.0 0.98,1.03 11522 23550
741 Symptoms and disorders of the joints musculoskeletal Both 0.8241 1.0 0.977,1.03 6764 29838 0.5176 0.918 0.707,1.19 58 596
741.1 Ankylosis of joint musculoskeletal Both 0.4753 1.05 0.914,1.21 209 2088 0.8337 1.02 0.879,1.17 202 1977
741.2 Stiffness of joint musculoskeletal Both 0.09333 1.06 0.991,1.13 995 9908 0.9204 0.996 0.924,1.07 745 9057
741.3 Difficulty in walking musculoskeletal Both 0.07244 1.04 0.996,1.1 1854 17778 0.04266 1.05 1.0,1.11 1715 16477
741.4 Joint effusions musculoskeletal Both 0.2904 1.03 0.979,1.07 1930 19185 0.5012 1.02 0.969,1.07 1763 17770
741.5 Hemarthrosis musculoskeletal Both 0.4457 0.908 0.71,1.16 64 640 0.5176 0.918 0.707,1.19 58 596
741.6 Villonodular synovitis musculoskeletal Both 0.9863 0.998 0.754,1.32 53 522 ,
742 Derangement of joint, non-traumatic musculoskeletal Both 0.4898 0.988 0.953,1.02 3462 27650 0.1675 0.973 0.937,1.01 2974 24966
742.1 Loose body in joint musculoskeletal Both 0.4207 0.931 0.782,1.11 131 1295 0.6699 0.962 0.807,1.15 127 1229
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.7031 0.974 0.853,1.11 243 2414 0.7295 0.976 0.852,1.12 235 2304
742.8 Articular cartilage disorder musculoskeletal Both 0.4853 0.948 0.816,1.1 191 1896 0.5781 0.958 0.822,1.12 183 1779
742.9 Other derangement of joint musculoskeletal Both 0.4198 0.985 0.95,1.02 3212 26883 0.1675 0.973 0.937,1.01 2974 24966
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.01 1.03 1.01,1.06 7571 30458 0.4365 1.01 0.981,1.04 4898 27900
743.1 Osteoporosis musculoskeletal Both 0.02138 1.05 1.01,1.09 2982 15823 0.04467 1.17 1.0,1.36 196 2071
743.11 Osteoporosis NOS musculoskeletal Both 0.01622 1.05 1.01,1.09 2931 15630 0.278 1.02 0.98,1.07 2401 14260
743.12 Senile osteoporosis musculoskeletal Both 0.6823 1.02 0.927,1.12 481 4333 0.869 0.991 0.886,1.11 350 3799
743.13 Other specified osteoporosis musculoskeletal Both 0.04169 1.15 1.01,1.33 231 2290 0.04467 1.17 1.0,1.36 196 2071
743.2 Pathologic fracture musculoskeletal Both 0.03162 1.08 1.01,1.16 872 8504 0.2388 1.14 0.917,1.41 93 1021
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.07943 1.1 0.989,1.22 385 3799 0.1841 1.08 0.965,1.2 349 3518
743.22 Pathologic fracture of femur musculoskeletal Both 0.2588 1.12 0.921,1.36 116 1143 0.2388 1.14 0.917,1.41 93 1021
743.4 Stress fracture musculoskeletal Both 0.871 0.99 0.876,1.12 291 2882 0.861 0.988 0.866,1.13 252 2643
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.02138 1.03 1.01,1.06 5795 29464 0.4365 1.01 0.981,1.04 4898 27900
745 Pain in joint musculoskeletal Both 0.8851 0.998 0.978,1.02 15755 22596 0.2793 0.988 0.968,1.01 14412 21245
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.6237 1.01 0.965,1.06 1811 18049 0.309 1.06 0.95,1.18 376 3710
747.1 Cardiac congenital anomalies congenital anomalies Both 0.865 1.0 0.952,1.06 1446 14417 0.1268 1.09 0.975,1.23 325 3200
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.4721 0.967 0.884,1.06 519 5181 0.7063 0.982 0.895,1.08 488 4768
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.3491 1.04 0.958,1.13 632 6299 0.3707 1.04 0.955,1.13 605 5995
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.05623 1.12 0.997,1.25 342 3387 0.1268 1.09 0.975,1.23 325 3200
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.3177 1.05 0.951,1.17 402 4014 0.309 1.06 0.95,1.18 376 3710
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.7834 0.97 0.781,1.2 93 930 0.7816 1.03 0.826,1.29 89 865
749 Congenital anomalies of face and neck congenital anomalies Both 0.08128 0.919 0.835,1.01 455 4540 0.1875 0.868 0.703,1.07 85 845
749.1 Cleft palate congenital anomalies Both 0.04365 0.787 0.624,0.993 81 791 0.05754 0.798 0.633,1.01 81 756
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.1954 0.873 0.711,1.07 90 897 0.1875 0.868 0.703,1.07 85 845
750 Digestive congenital anomalies congenital anomalies Both 0.1762 1.05 0.977,1.14 739 7382 0.1259 1.13 0.965,1.33 165 1606
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.7295 1.02 0.908,1.15 307 3069 0.5483 1.09 0.827,1.43 54 521
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.7278 1.04 0.845,1.27 96 944 0.5689 1.06 0.86,1.32 90 878
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.7889 0.968 0.76,1.23 77 767 0.8872 0.982 0.77,1.25 76 720
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.2761 1.11 0.922,1.33 121 1210 0.1578 1.15 0.948,1.39 112 1107
750.15 Congenital anomalies of stomach congenital anomalies Both 0.3622 1.13 0.865,1.49 57 567 0.5483 1.09 0.827,1.43 54 521
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.1038 1.08 0.983,1.2 438 4363 0.1259 1.13 0.965,1.33 165 1606
750.21 Congenital anomalies of intestine congenital anomalies Both 0.3681 1.06 0.934,1.2 262 2613 0.5035 1.05 0.917,1.19 239 2352
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.1718 1.11 0.955,1.3 180 1790 0.1259 1.13 0.965,1.33 165 1606
751 Genitourinary congenital anomalies congenital anomalies Both 0.241 1.03 0.98,1.08 1682 16764 0.7447 1.03 0.871,1.21 152 1447
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.369 1.04 0.952,1.14 491 4897 0.9506 0.994 0.836,1.18 131 1300
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.2286 1.07 0.957,1.2 328 3280 0.1361 1.1 0.971,1.24 283 2905
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.8375 0.982 0.825,1.17 132 1301 0.9506 0.994 0.836,1.18 131 1300
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.2931 1.03 0.973,1.1 1139 11355 0.7852 1.02 0.894,1.16 241 2337
751.21 Cystic kidney disease congenital anomalies Both 0.2312 1.04 0.972,1.12 799 7929 0.5662 1.02 0.948,1.1 740 7311
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.9661 0.997 0.877,1.13 251 2506 0.7852 1.02 0.894,1.16 241 2337
751.3 Obstructive genitourinary defect congenital anomalies Both 0.6745 1.04 0.879,1.22 157 1560 0.7447 1.03 0.871,1.21 152 1447
752 Nervous system congenital anomalies congenital anomalies Both 0.5848 0.981 0.916,1.05 908 9073 0.7852 1.02 0.879,1.19 195 1859
752.1 Neural tube defects congenital anomalies Both 0.867 0.994 0.921,1.07 728 7277 0.7943 0.977 0.823,1.16 136 1334
752.11 Spina bifida congenital anomalies Both 0.5 0.944 0.799,1.12 144 1440 0.7943 0.977 0.823,1.16 136 1334
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.861 1.01 0.875,1.17 201 2010 0.7852 1.02 0.879,1.19 195 1859
753 Congenital anomalies of the eye congenital anomalies Both 0.1972 0.891 0.748,1.06 146 1451 0.2438 0.898 0.749,1.08 134 1351
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.7362 1.01 0.948,1.08 1006 10049 0.3184 1.05 0.952,1.16 432 4202
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.7534 1.03 0.854,1.24 116 1155 0.4227 1.08 0.89,1.32 107 1052
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.8318 1.01 0.919,1.11 470 4675 0.3184 1.05 0.952,1.16 432 4202
755 Congenital anomalies of limbs congenital anomalies Both 0.631 0.98 0.904,1.06 625 6237 0.5129 0.944 0.794,1.12 145 1408
755.1 Congenital deformities of feet congenital anomalies Both 0.5224 1.04 0.925,1.17 315 3138 0.5093 1.04 0.923,1.17 293 2896
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.7278 0.954 0.731,1.24 58 567 0.7943 0.964 0.731,1.27 53 529
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.9016 0.992 0.875,1.13 258 2580 0.5129 0.944 0.794,1.12 145 1408
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.5875 0.955 0.807,1.13 152 1520 0.5129 0.944 0.794,1.12 145 1408
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.5585 0.981 0.92,1.05 1021 10203 0.1135 0.937 0.865,1.02 648 6858
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.3524 0.881 0.675,1.15 55 527 0.3236 0.871 0.663,1.15 51 486
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.6397 1.07 0.809,1.41 56 524 ,
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.7586 1.02 0.895,1.16 246 2459 0.695 1.03 0.898,1.17 233 2308
756.5 Congenital osteodystrophies congenital anomalies Both 0.6295 0.982 0.911,1.06 743 7419 0.1135 0.937 0.865,1.02 648 6858
757 Congenital anomalies of the integument congenital anomalies Both 0.9616 0.997 0.884,1.13 283 2820 0.7998 0.984 0.866,1.12 251 2565
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.7464 1.03 0.86,1.23 134 1334 0.826 0.975 0.777,1.22 85 863
758.1 Chromosomal anomalies congenital anomalies Both 0.8395 0.978 0.786,1.22 91 910 0.826 0.975 0.777,1.22 85 863
759 Other and unspecified congenital anomalies congenital anomalies Both 0.811 1.01 0.923,1.11 498 4964 0.07943 0.78 0.591,1.03 54 509
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.06761 0.775 0.59,1.02 57 567 0.07943 0.78 0.591,1.03 54 509
760 Back pain symptoms Both 0.2799 0.988 0.967,1.01 12687 25663 0.3715 0.99 0.968,1.01 11642 24016
761 Cervicalgia symptoms Both 0.2911 0.984 0.956,1.01 5134 32829 0.3027 0.984 0.954,1.01 4681 30591
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.4909 1.01 0.976,1.05 2927 27356 0.542 1.01 0.973,1.05 2708 25262
764 Sciatica symptoms Both 0.2388 1.02 0.984,1.07 2623 25291 0.7586 1.01 0.965,1.05 2377 23180
765 Cervical radiculitis symptoms Both 0.5272 0.982 0.93,1.04 1401 13966 0.5902 0.984 0.93,1.04 1299 12842
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.4819 0.988 0.956,1.02 4004 31031 0.4227 0.986 0.953,1.02 3692 28848
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.3936 1.1 0.884,1.37 85 835 0.4426 1.09 0.869,1.38 74 752
769 Nonallopathic lesions NEC symptoms Both 0.6353 1.02 0.95,1.09 923 9183 0.4457 1.03 0.957,1.11 808 8293
770 Myalgia and myositis unspecified symptoms Both 0.7413 0.995 0.963,1.03 4324 27592 0.6902 0.993 0.96,1.03 3849 25395
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.6699 1.01 0.973,1.04 3638 29710 0.7079 0.985 0.911,1.07 685 7133
771.1 Swelling of limb symptoms Both 0.2483 1.02 0.987,1.05 4511 29862 0.1795 1.02 0.99,1.06 4073 27906
771.2 Cramp of limb symptoms Both 0.7709 1.01 0.94,1.09 791 7856 0.7079 0.985 0.911,1.07 685 7133
772 Symptoms of the muscles symptoms Both 0.7295 1.01 0.958,1.06 1549 15345 0.2576 0.938 0.839,1.05 350 3432
772.1 Muscular wasting and disuse atrophy symptoms Both 0.8892 1.01 0.901,1.13 320 3187 0.5929 1.03 0.919,1.16 297 3026
772.2 Spasm of muscle symptoms Both 0.6053 0.987 0.94,1.04 1780 17782 0.8356 0.995 0.945,1.05 1633 16279
772.3 Muscle weakness symptoms Both 0.2421 0.975 0.934,1.02 2339 22770 0.4246 0.982 0.94,1.03 2164 21006
772.4 Rhabdomyolysis symptoms Both 0.3076 1.1 0.913,1.34 117 1170 0.2393 1.12 0.925,1.37 110 1102
772.6 Facial weakness symptoms Both 0.1663 0.927 0.832,1.03 377 3746 0.2576 0.938 0.839,1.05 350 3432
773 Pain in limb symptoms Both 0.5358 0.993 0.971,1.02 11393 26958 0.3837 0.99 0.967,1.01 10419 25239
780 Hypothermia/Chills symptoms Both 0.1905 1.08 0.962,1.21 307 3069 0.1531 1.09 0.968,1.23 272 2839
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.6683 1.01 0.962,1.06 1767 17206 0.3999 1.1 0.883,1.37 86 809
781.1 Loss of height symptoms Both 0.5093 1.07 0.868,1.33 91 890 0.3999 1.1 0.883,1.37 86 809
782.3 Edema symptoms Both 0.9462 0.999 0.968,1.03 4591 30849 0.778 0.995 0.963,1.03 4152 28801
782.6 Pallor and flushing symptoms Both 0.05623 1.08 0.998,1.16 679 6769 0.3034 0.951 0.865,1.05 443 6059
783 Fever of unknown origin symptoms Both 0.4093 1.01 0.982,1.04 4616 33703 0.6138 1.04 0.904,1.19 224 2322
783.1 Postprocedural fever symptoms Both 0.4932 1.05 0.919,1.19 248 2473 0.6138 1.04 0.904,1.19 224 2322
785 Abdominal pain symptoms Both 0.9528 1.0 0.98,1.02 13257 25098 0.9099 1.0 0.979,1.02 12224 23437
788 Syncope and collapse symptoms Both 0.1377 1.03 0.991,1.07 3017 29114 0.1016 1.03 0.994,1.07 2792 26968
789 Nausea and vomiting symptoms Both 0.2355 1.01 0.99,1.04 8497 29838 0.4083 0.965 0.886,1.05 580 5824
789.1 Persistent vomiting symptoms Both 0.6501 0.981 0.904,1.06 634 6330 0.4083 0.965 0.886,1.05 580 5824
790 Nonspecific findings on examination of blood symptoms Both 0.6668 0.989 0.941,1.04 1740 17356 0.07762 1.19 0.981,1.45 113 1127
790.1 Elevated sedimentation rate symptoms Both 0.2109 0.9 0.762,1.06 158 1580 0.2193 0.897 0.754,1.07 150 1401
790.6 Other abnormal blood chemistry symptoms Both 0.5212 0.99 0.96,1.02 4849 31554 0.3475 0.985 0.954,1.02 4380 29390
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.5445 0.956 0.827,1.11 204 2026 0.9078 0.991 0.854,1.15 197 1865
790.9 Abnormal arterial blood gases symptoms Both 0.03467 1.22 1.01,1.47 123 1230 0.07762 1.19 0.981,1.45 113 1127
791 Gangrene symptoms Both 0.8147 1.02 0.883,1.17 212 2104 0.7962 1.02 0.881,1.18 200 1977
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.1052 1.04 0.992,1.09 2171 11972 0.8035 1.01 0.937,1.09 764 7806
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.2667 1.04 0.969,1.12 841 7806 0.8035 1.01 0.937,1.09 764 7806
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.8995 0.995 0.914,1.08 588 5848 0.4966 0.981 0.929,1.04 1420 15272
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.811 0.994 0.945,1.05 1661 16601 0.4966 0.981 0.929,1.04 1420 15272
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.05495 1.1 0.998,1.22 433 4330 0.9506 1.0 0.892,1.13 302 3976
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.5383 0.984 0.936,1.04 1632 15619 0.9931 0.999 0.842,1.19 140 1448
795.8 Abnormal tumor markers symptoms Both 0.0302 0.945 0.898,0.995 1698 13664 0.9931 0.999 0.842,1.19 140 1448
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.857 0.986 0.843,1.15 167 1662 0.9931 0.999 0.842,1.19 140 1448
796 Elevated prostate specific antigen [PSA] symptoms Male 5.129E-4 0.909 0.861,0.959 1700 8294 4.169E-4 0.908 0.861,0.958 1693 8266
797 Shock symptoms Both 0.3342 1.05 0.952,1.16 445 4446 0.2344 1.1 0.941,1.28 174 1750
797.1 Cardiogenic shock symptoms Both 0.2301 1.1 0.943,1.28 183 1822 0.2344 1.1 0.941,1.28 174 1750
798 Malaise and fatigue symptoms Both 0.7691 1.0 0.98,1.03 8867 29476 0.7228 0.989 0.931,1.05 1142 12195
798.1 Chronic fatigue syndrome symptoms Both 0.863 1.0 0.95,1.06 1349 13380 0.7228 0.989 0.931,1.05 1142 12195
799 Debility unspecified symptoms Both 0.4508 0.981 0.933,1.03 1672 16007 0.6761 0.989 0.939,1.04 1546 14688
800 Fracture of lower limb injuries & poisonings Both 0.3221 0.977 0.932,1.02 1879 18684 0.1189 0.903 0.794,1.03 270 2674
800.1 Fracture of neck of femur injuries & poisonings Both 0.5808 0.972 0.878,1.08 409 4028 0.7656 0.984 0.885,1.09 374 3677
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.869 0.993 0.908,1.08 539 5364 0.6871 1.02 0.929,1.12 492 4926
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.4295 0.97 0.901,1.05 744 7420 0.6152 0.98 0.907,1.06 691 6915
800.4 Fracture of patella injuries & poisonings Both 0.1858 0.921 0.814,1.04 293 2904 0.1189 0.903 0.794,1.03 270 2674
801 Fracture of ankle and foot injuries & poisonings Both 0.5383 0.985 0.939,1.03 1804 17960 0.8492 0.993 0.925,1.07 834 8409
801.1 Fracture of foot injuries & poisonings Both 0.7998 0.991 0.927,1.06 913 9098 0.8492 0.993 0.925,1.07 834 8409
802 Fracture of pelvis injuries & poisonings Both 0.1671 1.08 0.968,1.21 321 3192 0.1496 1.09 0.97,1.22 301 2926
803 Fracture of upper limb injuries & poisonings Both 0.3428 0.976 0.927,1.03 1644 16288 0.2344 0.939 0.847,1.04 394 3995
803.1 Fracture of humerus injuries & poisonings Both 0.2056 0.947 0.869,1.03 592 5913 0.2529 0.949 0.868,1.04 536 5385
803.2 Fracture of radius and ulna injuries & poisonings Both 0.6934 0.986 0.921,1.06 899 8929 0.5848 0.963 0.842,1.1 221 2218
803.21 Colles' fracture injuries & poisonings Both 0.5495 0.962 0.848,1.09 248 2475 0.5848 0.963 0.842,1.1 221 2218
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.3236 0.951 0.86,1.05 419 4190 0.2344 0.939 0.847,1.04 394 3995
804 Fracture of hand or wrist injuries & poisonings Both 0.3451 0.973 0.919,1.03 1272 12504 0.5675 0.983 0.926,1.04 1180 11617
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.8166 1.01 0.947,1.07 1082 10755 0.6998 1.01 0.95,1.08 1015 9907
807 Fracture of ribs injuries & poisonings Both 0.8472 0.991 0.908,1.08 543 5428 0.5794 0.974 0.889,1.07 503 5087
809 Fracture of unspecified bones injuries & poisonings Both 0.2032 1.03 0.985,1.07 2426 23282 0.3381 1.02 0.978,1.07 2233 21591
817 Concussion injuries & poisonings Both 0.1507 0.948 0.88,1.02 771 7696 0.0912 0.937 0.868,1.01 728 7193
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.6855 0.973 0.85,1.11 240 2380 0.9638 1.01 0.799,1.27 80 779
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.3221 0.883 0.691,1.13 74 740 0.2466 0.86 0.667,1.11 68 688
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.8831 1.02 0.812,1.27 84 837 0.9638 1.01 0.799,1.27 80 779
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.1023 0.96 0.914,1.01 1782 17605 0.0871 0.957 0.91,1.01 1700 16536
830 Dislocation injuries & poisonings Both 0.9036 1.0 0.966,1.04 3129 28682 0.9908 1.0 0.962,1.04 2931 26605
835 Internal derangement of knee injuries & poisonings Both 0.3589 0.977 0.931,1.03 1774 17453 0.2333 0.97 0.922,1.02 1673 16353
836 Traumatic arthropathy injuries & poisonings Both 0.00263 0.856 0.773,0.947 423 4213 0.002512 0.851 0.766,0.945 394 3906
840 Sprains and strains injuries & poisonings Both 0.03467 0.971 0.944,0.998 6106 31582 0.03981 0.954 0.912,0.998 2145 18199
840.1 Muscle/tendon sprain injuries & poisonings Both 0.3266 0.952 0.864,1.05 429 4269 0.3412 0.952 0.86,1.05 402 3957
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.3069 0.971 0.918,1.03 1343 13394 0.1291 0.956 0.902,1.01 1252 12415
840.3 Joint/ligament sprain injuries & poisonings Both 0.02239 0.95 0.909,0.993 2261 19530 0.03981 0.954 0.912,0.998 2145 18199
841 Sprains and strains of back and neck injuries & poisonings Both 0.07244 0.947 0.892,1.0 1175 11729 0.01698 0.926 0.87,0.986 1064 10814
842 Other sprains and strains injuries & poisonings Both 0.001202 0.901 0.847,0.96 1079 10729 0.00123 0.898 0.842,0.959 999 10029
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.2148 1.03 0.983,1.08 1807 18037 0.7568 1.01 0.956,1.06 1468 16701
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.171 1.05 0.978,1.13 797 7958 0.1531 1.06 0.98,1.14 757 7539
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.2239 1.07 0.961,1.19 398 3977 0.1368 1.08 0.975,1.21 380 3707
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.2377 1.03 0.979,1.09 1537 15333 0.3882 1.02 0.97,1.08 1415 14378
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.9954 1.0 0.878,1.14 254 2540 0.7482 1.02 0.895,1.17 244 2371
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.4842 0.956 0.843,1.08 262 2617 0.863 0.989 0.869,1.13 248 2410
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.1694 0.959 0.904,1.02 1196 11925 0.2438 0.964 0.907,1.03 1135 11081
858 Complication of internal orthopedic device injuries & poisonings Both 0.7798 0.993 0.947,1.04 1892 18846 0.7096 0.991 0.943,1.04 1786 17559
859 Complication due to other implant and internal device injuries & poisonings Both 0.133 1.04 0.989,1.09 1820 18191 0.2985 1.03 0.976,1.08 1571 16873
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.5408 1.01 0.976,1.05 3389 30552 0.8851 0.986 0.815,1.19 112 1087
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.2624 1.1 0.931,1.3 156 1551 0.3148 1.09 0.919,1.3 145 1438
870.2 Open wound of ear injuries & poisonings Both 0.9863 0.998 0.828,1.2 114 1131 0.8913 1.01 0.835,1.23 108 1058
870.3 Other open wound of head and face injuries & poisonings Both 0.1545 1.05 0.983,1.12 1064 10560 0.1722 1.05 0.98,1.12 996 9839
870.4 Open wound of nose and sinus injuries & poisonings Both 0.547 0.953 0.813,1.12 168 1667 0.877 0.987 0.839,1.16 157 1539
870.5 Open wound of lip and mouth injuries & poisonings Both 0.7178 0.975 0.853,1.12 230 2293 0.5176 0.955 0.832,1.1 216 2164
870.6 Open wound of neck injuries & poisonings Both 0.07762 1.15 0.985,1.34 184 1833 0.1413 1.13 0.962,1.32 176 1763
870.8 Open wound of genital organs injuries & poisonings Both 0.861 0.983 0.816,1.19 117 1170 0.8851 0.986 0.815,1.19 112 1087
871 Open wounds of extremities injuries & poisonings Both 0.9572 1.0 0.962,1.04 2705 26585 0.6918 1.03 0.883,1.21 169 1767
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.859 1.01 0.916,1.11 438 4378 0.9141 1.01 0.911,1.11 415 4117
871.2 Open wound of finger(s) injuries & poisonings Both 0.8892 0.995 0.922,1.07 731 7291 0.6668 0.983 0.909,1.06 678 6846
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.9616 1.0 0.896,1.12 331 3277 0.6124 1.03 0.918,1.16 315 3083
871.4 Open wound of toe(s) injuries & poisonings Both 0.7745 1.02 0.881,1.18 191 1901 0.6918 1.03 0.883,1.21 169 1767
872 Traumatic amputation injuries & poisonings Both 0.01479 1.13 1.02,1.25 415 4129 0.0263 1.12 1.01,1.24 402 3966
873 Broken tooth injuries & poisonings Both 0.6998 0.968 0.818,1.14 148 1471 0.542 0.948 0.797,1.13 138 1383
874 Complication of amputation stump injuries & poisonings Both 0.302 1.1 0.915,1.33 122 1220 0.2767 1.11 0.92,1.34 122 1187
875 Non-healing surgical wound injuries & poisonings Both 0.5236 0.971 0.886,1.06 495 4950 0.3373 0.954 0.867,1.05 446 4544
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.008128 1.11 1.03,1.21 669 6680 0.00871 1.12 1.03,1.22 607 6196
907 Injuries to the nervous system injuries & poisonings Both 0.2188 0.958 0.894,1.03 888 8852 0.3243 0.965 0.899,1.04 841 8287
910 Superficial injury, infected injuries & poisonings Both 0.811 0.973 0.78,1.21 89 887 0.7656 0.967 0.773,1.21 86 834
911 Blister injuries & poisonings Both 0.002291 1.26 1.09,1.46 185 1838 0.008511 1.23 1.06,1.44 164 1689
912 Insect bite injuries & poisonings Both 0.9886 1.0 0.89,1.13 321 3207 0.9226 0.994 0.878,1.13 290 2931
913 Toxic effect of venom injuries & poisonings Both 0.5794 1.04 0.908,1.19 247 2461 0.4395 1.06 0.919,1.21 226 2258
915 Superficial injury without mention of infection injuries & poisonings Both 0.8872 1.0 0.962,1.05 2368 23457 0.5572 0.987 0.944,1.03 2167 21657
916 Contusion injuries & poisonings Both 0.7745 1.01 0.969,1.04 3199 30228 0.8222 1.0 0.967,1.04 2901 27936
930 Allergic reaction to food injuries & poisonings Both 0.7096 1.02 0.935,1.1 597 5953 0.9333 1.0 0.92,1.09 539 5441
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.4831 0.969 0.886,1.06 530 5290 0.5272 0.97 0.884,1.07 479 4906
938 Dermatitis due to solar radiation injuries & poisonings Both 0.6138 0.992 0.959,1.02 4197 24407 0.2844 0.981 0.947,1.02 3602 22446
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.4416 1.06 0.91,1.24 164 1640 0.3945 1.07 0.913,1.26 152 1524
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.7621 0.995 0.962,1.03 4001 24007 0.2844 0.981 0.947,1.02 3602 22446
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.7295 0.97 0.818,1.15 140 1400 0.8318 0.981 0.822,1.17 126 1289
942 Infusion and transfusion reaction injuries & poisonings Both 0.228 0.92 0.803,1.05 221 2205 0.2339 0.918 0.797,1.06 205 2057
946 Anaphylactic shock NOS injuries & poisonings Both 0.1156 0.919 0.827,1.02 385 3830 0.309 0.945 0.846,1.05 353 3541
947 Urticaria injuries & poisonings Both 0.984 1.0 0.935,1.07 889 8845 0.5129 0.976 0.908,1.05 787 8122
949 Allergies, other injuries & poisonings Both 0.6457 0.993 0.964,1.02 5269 26807 0.2851 0.983 0.952,1.01 4679 25237
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.9863 0.999 0.903,1.11 419 4176 0.9772 1.0 0.903,1.11 401 3946
957 Injury to other and unspecified nerves injuries & poisonings Both 0.2999 0.906 0.752,1.09 116 1150 0.2917 0.902 0.744,1.09 111 1078
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.6577 1.01 0.953,1.08 1073 10721 0.8954 1.01 0.819,1.26 91 861
958.1 Postoperative shock injuries & poisonings Both 0.7079 0.967 0.811,1.15 133 1325 0.8279 0.981 0.822,1.17 133 1246
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.873 1.02 0.822,1.26 92 911 0.8954 1.01 0.819,1.26 91 861
960 Poisoning by antibiotics injuries & poisonings Both 0.2004 1.03 0.984,1.08 2108 18753 0.3715 1.03 0.969,1.09 1296 12855
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.5093 1.06 0.899,1.24 158 1552 0.7063 1.03 0.871,1.23 135 1442
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.2858 1.03 0.975,1.09 1414 13864 0.3715 1.03 0.969,1.09 1296 12855
961 Poisoning by other anti-infectives injuries & poisonings Both 0.9795 0.999 0.909,1.1 470 4694 0.2944 1.04 0.968,1.11 848 8400
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.157 1.05 0.982,1.12 939 9190 0.2944 1.04 0.968,1.11 848 8400
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.08913 1.08 0.989,1.18 561 5601 0.4864 1.05 0.921,1.19 270 2846
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.1242 1.1 0.975,1.23 308 3069 0.09333 1.11 0.983,1.25 289 2896
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.2449 1.07 0.953,1.21 305 3029 0.4864 1.05 0.921,1.19 270 2846
963 Poisoning by primarily systemic agents injuries & poisonings Both 1.514E-4 1.09 1.04,1.14 2031 19919 0.1086 1.05 0.99,1.1 1390 18093
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 1.0E-4 1.1 1.05,1.15 1980 19507 0.1086 1.05 0.99,1.1 1390 18093
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.5715 0.975 0.892,1.07 538 5360 0.6138 0.976 0.888,1.07 470 4755
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.6252 0.977 0.892,1.07 509 5070 0.6138 0.976 0.888,1.07 470 4755
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.5546 1.02 0.949,1.1 753 7525 0.2812 1.12 0.909,1.39 92 923
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.7211 1.01 0.954,1.07 1305 12848 0.6622 1.01 0.954,1.08 1190 11839
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.342 1.1 0.9,1.36 98 967 0.2812 1.12 0.909,1.39 92 923
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.5623 1.07 0.856,1.33 86 850 0.6998 1.05 0.832,1.31 82 803
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.4416 1.03 0.961,1.09 1000 9986 0.8185 0.992 0.926,1.06 883 9224
969 Poisoning by psychotropic agents injuries & poisonings Both 0.1374 1.11 0.968,1.26 234 2331 0.1245 1.11 0.97,1.28 213 2175
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.2472 1.17 0.898,1.52 56 546 0.4634 1.11 0.845,1.45 53 520
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.9616 0.997 0.871,1.14 228 2269 0.6324 1.06 0.843,1.33 81 808
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.9057 0.985 0.773,1.26 66 637 0.9016 0.984 0.764,1.27 59 596
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.6839 1.05 0.841,1.3 86 860 0.6324 1.06 0.843,1.33 81 808
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.865 1.02 0.822,1.26 90 896 0.873 1.02 0.812,1.28 81 837
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.3327 1.12 0.888,1.42 69 686 0.2871 1.14 0.897,1.45 67 650
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.2831 1.15 0.89,1.49 60 600 0.2018 1.19 0.912,1.55 57 555
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.7889 0.993 0.943,1.05 1565 14843 0.6138 0.986 0.933,1.04 1417 13743
979 Adverse drug events and drug allergies injuries & poisonings Both 0.5383 1.01 0.97,1.06 2116 20636 0.8433 1.0 0.958,1.05 1850 19241
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.4592 1.08 0.875,1.34 91 904 0.2317 1.15 0.916,1.44 83 837
990 Effects radiation NOS injuries & poisonings Both 1.514E-4 1.08 1.04,1.12 2707 23906 0.2972 1.02 0.979,1.07 2157 22289
994 Sepsis and SIRS injuries & poisonings Both 0.5943 1.01 0.965,1.06 1724 17160 0.8995 1.01 0.916,1.11 464 4567
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.7244 1.02 0.901,1.16 248 2472 0.7925 1.02 0.893,1.16 232 2318
994.2 Sepsis injuries & poisonings Both 0.7194 1.01 0.959,1.06 1636 16281 0.8995 1.01 0.916,1.11 464 4567
994.21 Septic shock injuries & poisonings Both 0.9863 0.999 0.911,1.1 484 4840 0.8995 1.01 0.916,1.11 464 4567
1000 Burns injuries & poisonings Both 0.8054 0.99 0.912,1.07 638 6350 0.3724 0.962 0.883,1.05 581 5907
1001 Foreign body injury injuries & poisonings Both 0.5702 0.988 0.947,1.03 2372 22762 0.7031 0.992 0.949,1.04 2239 21548
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.3908 1.01 0.983,1.04 4830 32603 0.3273 1.02 0.984,1.05 4531 30232
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.5224 1.02 0.96,1.08 1136 11344 0.4508 1.02 0.961,1.09 1030 10539
1005 Other symptoms injuries & poisonings Both 0.8851 0.998 0.973,1.02 7724 30626 0.4753 0.991 0.965,1.02 7040 28617
1006 Crushing injury injuries & poisonings Both 0.9397 0.995 0.874,1.13 245 2437 0.9954 1.0 0.876,1.14 237 2319
1007 Injury to blood vessels injuries & poisonings Both 0.0195 0.887 0.802,0.981 411 4106 0.06026 0.905 0.816,1.0 383 3851
1008 Crushing or internal injury to organs injuries & poisonings Both 0.5623 1.02 0.954,1.09 934 9331 0.4932 1.02 0.956,1.1 890 8777
1009 Injury, NOS injuries & poisonings Both 0.6592 1.01 0.982,1.03 9284 29063 0.6471 0.994 0.97,1.02 8530 27123
1010 Other tests injuries & poisonings Both 0.9484 0.999 0.979,1.02 19027 19331 0.3451 0.99 0.97,1.01 17301 18363
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.6808 1.01 0.978,1.03 5922 32336 0.8511 0.997 0.968,1.03 5281 30284
1012 Late effect injuries & poisonings Both 0.5861 1.02 0.949,1.1 792 7909 0.695 1.02 0.942,1.09 735 7309
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.166 1.03 0.988,1.07 2459 23709 0.1291 1.03 0.99,1.08 2289 21945
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.4217 1.06 0.914,1.24 177 1770 0.4467 1.06 0.907,1.25 162 1644
1015 Effects of other external causes injuries & poisonings Both 0.6324 0.993 0.966,1.02 5744 32595 0.7621 0.995 0.966,1.03 5224 30423
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.5916 1.01 0.969,1.06 2208 21537 0.7194 1.01 0.964,1.06 2040 19905
1100 Family history injuries & poisonings Both 0.618 1.04 0.902,1.19 222 2220 0.6095 1.04 0.896,1.21 195 1998
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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