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UKB PRS for Melanomas of skin, dx or hx(172.1) based on Ransohoff KJ et al. 2017
GWAS reference: 28212542 GWAS source: Ransohoff KJ et al. 2017 PRS method: P&T
PRSweb LD reference: MGI GWAS phenotype: Melanomas of skin, dx or hx PRSweb date: 2020-06-20
GWAS ID: Melanoma_Ransohoff GWAS URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/28212542/ Genome build: GRCh37/hg19
PRS tuning parameter: P<=3.5e-08 PRS evaluation in: UKB
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.8279 0.998 0.976,1.02 8842 88430 0.4305 0.974 0.912,1.04 964 9771
008.5 Bacterial enteritis infectious diseases Both 0.227 0.976 0.938,1.02 2718 27172 0.4169 1.04 0.952,1.13 607 6267
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.4645 1.03 0.95,1.12 653 6533 0.4169 1.04 0.952,1.13 607 6267
008.6 Viral Enteritis infectious diseases Both 0.6934 1.01 0.946,1.09 862 8622 0.5888 1.02 0.949,1.1 808 8275
008.7 Intestinal infection due to protozoa infectious diseases Both 0.4064 1.12 0.859,1.46 55 550 0.6039 1.07 0.823,1.4 53 533
010 Tuberculosis infectious diseases Both 0.2188 0.904 0.769,1.06 166 1659 0.2168 1.02 0.99,1.05 5692 57250
038 Septicemia infectious diseases Both 0.7261 1.01 0.974,1.04 4175 41776 0.7129 0.982 0.894,1.08 473 4756
038.1 Gram negative septicemia infectious diseases Both 0.9036 0.996 0.928,1.07 850 8501 0.7551 0.989 0.919,1.06 803 8157
038.2 Gram positive septicemia infectious diseases Both 0.8995 0.994 0.906,1.09 494 4978 0.7129 0.982 0.894,1.08 473 4756
041 Bacterial infection NOS infectious diseases Both 0.7211 1.0 0.985,1.02 12017 120377 0.4457 0.984 0.945,1.03 2597 26247
041.1 Staphylococcus infections infectious diseases Both 0.3467 1.02 0.981,1.06 3128 31348 0.4256 1.02 0.978,1.05 2961 30113
041.2 Streptococcus infection infectious diseases Both 0.7516 0.992 0.942,1.04 1641 16433 0.6427 0.988 0.937,1.04 1554 15843
041.4 E. coli infectious diseases Both 0.7112 0.992 0.954,1.03 2730 27319 0.4457 0.984 0.945,1.03 2597 26247
053 Herpes zoster infectious diseases Both 0.6166 0.974 0.881,1.08 411 4137 0.6442 0.952 0.772,1.17 94 917
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.5585 0.94 0.764,1.16 95 949 0.6442 0.952 0.772,1.17 94 917
054 Herpes simplex infectious diseases Both 0.6237 1.03 0.902,1.19 211 2107 0.7261 1.03 0.892,1.18 203 2046
070 Viral hepatitis infectious diseases Both 0.335 1.04 0.958,1.13 590 5916 0.1897 0.934 0.844,1.03 403 4124
070.1 Viral hepatitis A infectious diseases Both 0.3243 0.881 0.685,1.13 69 690 0.5395 0.922 0.711,1.2 66 665
070.2 Viral hepatitis B infectious diseases Both 0.7447 1.03 0.862,1.23 132 1330 0.8091 1.02 0.851,1.23 123 1288
070.3 Viral hepatitis C infectious diseases Both 0.3556 1.06 0.933,1.21 255 2568 0.4667 1.05 0.919,1.2 247 2508
070.4 Chronic hepatitis infectious diseases Both 0.6383 0.97 0.856,1.1 276 2767 0.7568 0.98 0.86,1.12 253 2668
070.9 Hepatitis NOS infectious diseases Both 0.3162 0.951 0.861,1.05 428 4287 0.1897 0.934 0.844,1.03 403 4124
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.4797 1.06 0.896,1.26 147 1467 0.6668 1.04 0.858,1.27 109 1140
071.1 HIV infection, symptomatic infectious diseases Both 0.4365 1.08 0.891,1.31 117 1168 0.6668 1.04 0.858,1.27 109 1140
078 Viral warts & HPV infectious diseases Both 0.04169 1.07 1.0,1.14 1004 10036 0.1 1.06 0.989,1.13 913 9745
079 Viral infection infectious diseases Both 0.6982 0.992 0.954,1.03 2769 27694 0.9162 1.01 0.783,1.31 60 626
079.1 Varicella infection infectious diseases Both 0.492 1.09 0.85,1.4 64 640 0.9162 1.01 0.783,1.31 60 626
080 Postoperative infection infectious diseases Both 0.6622 0.993 0.963,1.02 4473 44775 0.4018 0.987 0.956,1.02 4234 43158
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.7228 1.01 0.967,1.05 2477 24765 0.6339 1.01 0.968,1.05 2353 23841
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.7586 0.963 0.759,1.22 71 709 0.5821 0.934 0.733,1.19 68 686
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.8954 1.01 0.891,1.14 279 2810 0.3412 0.918 0.771,1.09 134 1370
110.1 Dermatophytosis infectious diseases Both 0.7745 1.02 0.899,1.15 273 2750 0.3412 0.918 0.771,1.09 134 1370
110.11 Dermatophytosis of nail infectious diseases Both 0.07762 1.24 0.977,1.56 74 756 0.09772 1.23 0.963,1.57 67 725
110.12 Althete's foot infectious diseases Both 0.3304 0.918 0.774,1.09 141 1410 0.3412 0.918 0.771,1.09 134 1370
112 Candidiasis infectious diseases Both 0.4256 1.02 0.974,1.06 2126 21275 0.3013 1.02 0.979,1.07 2020 20395
117 Mycoses infectious diseases Both 0.7362 1.02 0.902,1.16 272 2719 0.6982 0.968 0.823,1.14 161 1591
117.4 Aspergillosis infectious diseases Both 0.7278 0.972 0.827,1.14 165 1650 0.6982 0.968 0.823,1.14 161 1591
130 Spirochetal infection infectious diseases Both 0.9247 1.01 0.807,1.27 80 800 0.8995 1.01 0.81,1.27 80 764
133 Arthropod-borne diseases infectious diseases Both 0.8492 0.976 0.758,1.26 69 689 0.5321 0.919 0.705,1.2 62 668
134 Helminthiases infectious diseases Both 0.929 1.01 0.841,1.21 127 1267 0.5546 1.06 0.868,1.3 103 1028
134.1 Intestinal helminthiases infectious diseases Both 0.4775 1.08 0.88,1.31 106 1058 0.5546 1.06 0.868,1.3 103 1028
136 Other infectious and parasitic diseases infectious diseases Both 0.3289 1.07 0.93,1.24 205 2050 0.2748 1.09 0.936,1.26 193 1974
145 Cancer of mouth neoplasms Both 0.05888 1.08 0.997,1.17 642 6415 0.3673 1.14 0.859,1.51 52 510
145.2 Cancer of tongue neoplasms Both 0.9419 1.0 0.893,1.13 310 3096 0.7015 0.977 0.866,1.1 294 2982
145.3 Cancer of major salivary glands neoplasms Both 0.1778 1.15 0.938,1.42 105 1049 0.1959 1.15 0.93,1.43 96 1009
145.5 Cancer of the mouth floor neoplasms Both 0.114 1.24 0.949,1.62 54 539 0.3673 1.14 0.859,1.51 52 510
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.5572 1.02 0.944,1.11 635 6342 0.2944 1.07 0.942,1.22 252 2503
149.1 Cancer of oropharynx neoplasms Both 0.4955 0.955 0.838,1.09 252 2517 0.5212 0.957 0.836,1.09 238 2405
149.4 Cancer of larynx neoplasms Both 0.3516 1.06 0.937,1.2 265 2640 0.2944 1.07 0.942,1.22 252 2503
149.9 Cancer of of nasal cavities neoplasms Both 0.6561 1.06 0.811,1.39 57 570 ,
150 Cancer of esophagus neoplasms Both 0.207 0.953 0.885,1.03 762 7630 0.1923 0.95 0.881,1.03 727 7280
151 Cancer of stomach neoplasms Both 0.2286 0.948 0.869,1.03 569 5696 0.1862 0.942 0.861,1.03 545 5416
153 Colorectal cancer neoplasms Both 0.8974 1.0 0.972,1.03 4580 45799 0.2014 0.97 0.927,1.02 2018 20705
153.2 Colon cancer neoplasms Both 0.2138 1.02 0.987,1.06 3105 31046 0.3776 1.02 0.979,1.06 2922 29675
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.3664 0.98 0.937,1.02 2164 21640 0.2014 0.97 0.927,1.02 2018 20705
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.2223 1.07 0.962,1.18 400 4008 0.2254 1.11 0.938,1.31 149 1509
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.1026 1.15 0.973,1.35 158 1580 0.2254 1.11 0.938,1.31 149 1509
157 Pancreatic cancer neoplasms Both 0.5998 0.979 0.904,1.06 659 6582 0.4581 0.97 0.895,1.05 633 6289
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.9661 0.999 0.938,1.06 1063 10635 0.6546 0.985 0.924,1.05 999 10182
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.6324 0.993 0.966,1.02 5567 55694 0.514 0.951 0.817,1.11 185 1841
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.9727 1.0 0.864,1.16 190 1900 0.912 1.01 0.866,1.17 181 1819
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.7534 0.978 0.849,1.13 205 2048 0.9162 0.992 0.858,1.15 194 1950
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.5649 0.957 0.825,1.11 193 1925 0.514 0.951 0.817,1.11 185 1841
164 Cancer of intrathoracic organs neoplasms Both 0.5297 1.09 0.838,1.41 60 600 0.3556 1.13 0.871,1.47 58 573
165 Cancer within the respiratory system neoplasms Both 0.2312 1.02 0.985,1.06 2824 28235 0.3105 1.02 0.979,1.07 2121 21338
165.1 Cancer of bronchus; lung neoplasms Both 0.2564 1.03 0.982,1.07 2230 22307 0.3105 1.02 0.979,1.07 2121 21338
170 Cancer of bone and connective tissue neoplasms Both 0.3589 1.05 0.949,1.16 437 4364 0.8356 1.01 0.898,1.14 292 3183
170.1 Bone cancer neoplasms Both 0.5834 0.952 0.797,1.14 131 1309 0.3681 0.919 0.763,1.11 118 1245
170.2 Cancer of connective tissue neoplasms Both 0.2382 1.07 0.956,1.2 331 3303 0.8356 1.01 0.898,1.14 292 3183
172 Skin cancer neoplasms Both 1.0E-169 1.29 1.27,1.31 13495 134987 ,
172.1 Melanomas of skin, dx or hx neoplasms Both 3.162E-77 1.46 1.41,1.52 2681 26792 ,
172.11 Melanomas of skin neoplasms Both 3.162E-77 1.46 1.4,1.52 2713 27112 ,
172.2 Other non-epithelial cancer of skin neoplasms Both 1.0E-120 1.27 1.24,1.29 11000 110056 ,
172.3 Carcinoma in situ of skin neoplasms Both 1.585E-14 1.37 1.27,1.49 666 6656 ,
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.02951 1.19 1.02,1.38 181 1818 0.133 1.14 0.96,1.36 137 1818
174 Breast cancer neoplasms Both 5.37E-4 1.03 1.01,1.05 12686 126597 0.3639 0.916 0.758,1.11 111 1111
174.1 Breast cancer [female] neoplasms Female 3.89E-4 1.03 1.02,1.05 12476 124506 5.37E-4 1.03 1.01,1.06 11228 113531
174.11 Malignant neoplasm of female breast neoplasms Female 6.607E-4 1.03 1.01,1.05 11757 117502 5.37E-4 1.03 1.01,1.06 11228 113531
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.1982 0.885 0.734,1.07 115 1148 0.3639 0.916 0.758,1.11 111 1111
175 Acquired absence of breast neoplasms Female 0.08913 1.04 0.994,1.08 2400 24010 0.1469 1.03 0.989,1.08 2282 23220
180 Cervical cancer and dysplasia neoplasms Female 0.5 0.985 0.942,1.03 2174 21747 0.6501 0.989 0.945,1.04 2025 20287
180.1 Cervical cancer neoplasms Female 0.302 0.937 0.829,1.06 272 2720 0.3548 0.943 0.834,1.07 268 2640
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.7674 0.993 0.949,1.04 2078 20784 0.6501 0.989 0.945,1.04 2025 20287
182 Malignant neoplasm of uterus neoplasms Female 0.9594 0.999 0.943,1.06 1282 12836 0.8995 1.0 0.947,1.06 1226 12355
184 Cancer of other female genital organs neoplasms Female 0.9226 0.997 0.944,1.05 1378 13772 0.3475 0.942 0.832,1.07 279 2963
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.6839 1.01 0.949,1.08 967 9667 0.8091 0.992 0.926,1.06 899 9058
184.11 Malignant neoplasm of ovary neoplasms Female 0.8995 1.0 0.939,1.07 939 9387 0.8091 0.992 0.926,1.06 899 9058
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.6166 0.97 0.861,1.09 305 3049 0.3475 0.942 0.832,1.07 279 2963
185 Cancer of prostate neoplasms Male 0.6714 1.01 0.979,1.03 5974 58812 0.8453 1.0 0.975,1.03 5586 55793
187 Cancer of other male genital organs neoplasms Male 0.9016 0.994 0.902,1.1 449 4485 0.2667 0.893 0.732,1.09 107 1048
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.861 0.978 0.767,1.25 70 700 0.5534 1.08 0.834,1.4 60 675
187.2 Malignant neoplasm of testis neoplasms Male 0.6194 1.03 0.916,1.16 287 2868 0.7079 1.02 0.908,1.15 277 2799
187.8 Neoplasm of uncertain behavior of male genital organs neoplasms Male 0.2084 0.881 0.724,1.07 110 1098 0.2667 0.893 0.732,1.09 107 1048
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.2228 0.98 0.949,1.01 4160 41604 0.2992 0.909 0.76,1.09 129 1369
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.9886 0.999 0.938,1.07 1073 10723 0.3565 0.884 0.681,1.15 58 622
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.865 1.01 0.943,1.07 1033 10324 0.6561 1.02 0.95,1.09 983 9870
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.4188 0.903 0.705,1.16 66 660 0.3565 0.884 0.681,1.15 58 622
189.2 Cancer of bladder neoplasms Both 0.7962 0.995 0.954,1.04 2409 24113 0.3251 0.977 0.934,1.02 2032 20386
189.21 Malignant neoplasm of bladder neoplasms Both 0.5794 0.988 0.945,1.03 2142 21447 0.3251 0.977 0.934,1.02 2032 20386
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.547 0.949 0.801,1.12 144 1439 0.2992 0.909 0.76,1.09 129 1369
190 Cancer of eye neoplasms Both 0.6501 1.04 0.888,1.21 176 1758 0.7852 1.02 0.866,1.21 147 1679
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.9484 1.0 0.927,1.08 689 6879 0.4909 1.03 0.943,1.13 503 5023
191.1 Cancer of brain and nervous system neoplasms Both 0.6577 1.02 0.936,1.11 566 5650 0.4909 1.03 0.943,1.13 503 5023
191.11 Cancer of brain neoplasms Both 0.6683 1.02 0.933,1.11 525 5240 0.4909 1.03 0.943,1.13 503 5023
193 Thyroid cancer neoplasms Both 0.7278 1.02 0.913,1.14 346 3466 0.9204 0.994 0.888,1.11 327 3350
194 Cancer of other endocrine glands neoplasms Both 0.414 1.1 0.88,1.37 95 949 0.3258 1.12 0.895,1.4 91 909
195 Cancer, suspected or other neoplasms Both 3.981E-17 1.07 1.05,1.09 16967 165463 0.02399 1.02 1.0,1.04 12892 154276
195.1 Malignant neoplasm, other neoplasms Both 3.162E-17 1.07 1.05,1.09 16267 159497 0.02399 1.02 1.0,1.04 12892 154276
197 Chemotherapy neoplasms Both 0.01995 1.02 1.0,1.03 21433 213213 0.1279 1.01 0.997,1.03 20337 206935
198 Secondary malignant neoplasm neoplasms Both 0.03162 1.02 1.0,1.05 9552 95503 0.6714 0.96 0.797,1.16 114 1836
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.1432 1.02 0.993,1.05 5368 53670 0.859 1.0 0.974,1.03 4917 52033
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.3499 1.02 0.978,1.07 2267 22670 0.9057 0.997 0.953,1.04 2068 21940
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.6918 0.99 0.939,1.04 1549 15496 0.2541 0.969 0.918,1.02 1435 15001
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.3673 1.02 0.979,1.06 2665 26648 0.7516 1.01 0.966,1.05 2495 25756
198.5 Secondary malignancy of brain/spine neoplasms Both 0.05129 1.07 0.999,1.15 848 8473 0.4395 1.03 0.956,1.11 755 8236
198.6 Secondary malignancy of bone neoplasms Both 0.1968 1.03 0.985,1.08 2161 21600 0.561 1.01 0.968,1.06 2029 20888
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.3155 1.08 0.93,1.25 188 1890 0.6714 0.96 0.797,1.16 114 1836
199 Neoplasm of uncertain behavior neoplasms Both 0.6561 1.01 0.959,1.07 1432 14313 0.1849 0.869 0.706,1.07 92 929
199.4 Neurofibromatosis neoplasms Both 0.07762 0.832 0.677,1.02 95 950 0.1849 0.869 0.706,1.07 92 929
200 Myeloproliferative disease neoplasms Both 0.07413 1.06 0.994,1.13 991 9911 0.03548 1.12 1.01,1.25 365 3692
200.1 Polycythemia vera neoplasms Both 0.02344 1.13 1.02,1.25 387 3867 0.03548 1.12 1.01,1.25 365 3692
201 Hodgkin's disease neoplasms Both 0.4592 0.954 0.841,1.08 259 2598 0.507 0.958 0.843,1.09 250 2507
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.873 0.996 0.954,1.04 2264 22709 0.4786 1.03 0.945,1.13 540 5562
202.2 Non-Hodgkins lymphoma neoplasms Both 0.9616 0.999 0.951,1.05 1802 18073 0.4786 1.03 0.945,1.13 540 5562
202.21 Nodular lymphoma neoplasms Both 0.6745 0.977 0.875,1.09 363 3647 0.4027 0.953 0.85,1.07 338 3500
202.24 Large cell lymphoma neoplasms Both 0.5808 1.02 0.94,1.12 581 5824 0.4786 1.03 0.945,1.13 540 5562
204 Leukemia neoplasms Both 0.4365 1.02 0.97,1.07 1660 16630 0.4102 1.04 0.948,1.14 515 5338
204.1 Lymphoid leukemia neoplasms Both 0.3758 1.04 0.954,1.13 577 5784 0.6871 1.02 0.925,1.13 449 4844
204.11 Lymphoid leukemia, acute neoplasms Both 0.6546 1.06 0.81,1.4 56 560 0.6592 1.07 0.803,1.41 53 545
204.12 Lymphoid leukemia, chronic neoplasms Both 0.6546 1.02 0.931,1.12 507 5084 0.6871 1.02 0.925,1.13 449 4844
204.2 Myeloid leukemia neoplasms Both 0.4111 1.04 0.947,1.14 462 4617 0.4742 1.07 0.894,1.27 131 1392
204.21 Myeloid leukemia, acute neoplasms Both 0.4246 1.05 0.936,1.17 329 3287 0.3864 1.05 0.938,1.18 312 3151
204.22 Myeloid leukemia, chronic neoplasms Both 0.3381 1.09 0.917,1.29 144 1440 0.4742 1.07 0.894,1.27 131 1392
204.4 Multiple myeloma neoplasms Both 0.5047 1.03 0.943,1.13 555 5560 0.4102 1.04 0.948,1.14 515 5338
208 Benign neoplasm of colon neoplasms Both 0.08318 1.01 0.998,1.03 19856 191891 0.1297 1.01 0.997,1.03 18851 184234
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.0955 1.06 0.99,1.13 978 9781 0.06026 1.07 0.997,1.14 949 9456
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.865 1.0 0.974,1.03 5243 52452 0.8299 1.0 0.974,1.03 5005 50355
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.5636 0.968 0.866,1.08 347 3466 0.537 0.965 0.862,1.08 335 3331
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.6653 1.03 0.915,1.15 318 3187 0.4645 1.04 0.93,1.17 307 3109
214 Lipoma neoplasms Both 0.4539 1.01 0.984,1.04 6231 62346 0.9354 0.999 0.968,1.03 4355 44315
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.8241 1.0 0.973,1.03 4585 45872 0.9354 0.999 0.968,1.03 4355 44315
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.561 1.02 0.958,1.08 1107 11061 0.7834 1.01 0.947,1.07 1048 10681
216 Benign neoplasm of skin neoplasms Both 7.943E-15 1.1 1.07,1.12 7664 76660 2.138E-5 1.06 1.03,1.08 6446 74370
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.1552 1.06 0.978,1.15 632 6313 0.389 1.04 0.952,1.14 531 5747
217.1 Nevus, non-neoplastic neoplasms Both 0.1216 1.07 0.983,1.16 595 5943 0.389 1.04 0.952,1.14 531 5747
218 Benign neoplasm of uterus neoplasms Female 0.1062 1.02 0.996,1.04 10023 100200 0.3041 0.942 0.841,1.06 337 3457
218.1 Uterine leiomyoma neoplasms Female 0.0257 1.02 1.0,1.04 10241 102376 0.04571 1.02 1.0,1.04 9913 99546
218.2 Other benign neoplasm of uterus neoplasms Female 0.4295 0.956 0.856,1.07 355 3548 0.3041 0.942 0.841,1.06 337 3457
220 Benign neoplasm of ovary neoplasms Female 0.4027 1.02 0.969,1.08 1445 14483 0.4853 1.02 0.965,1.08 1396 14013
221 Benign neoplasm of other female genital organs neoplasms Female 0.5559 0.959 0.833,1.1 220 2196 0.4955 0.951 0.823,1.1 206 2124
222 Benign neoplasm of male genital organs neoplasms Male 0.03311 0.835 0.707,0.986 160 1600 0.02884 0.828 0.699,0.98 154 1535
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.6516 0.966 0.829,1.12 173 1729 0.869 0.987 0.846,1.15 166 1658
224 Benign neoplasm of eye neoplasms Both 0.8035 0.978 0.818,1.17 129 1299 0.2858 1.15 0.892,1.47 65 640
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.2944 1.14 0.891,1.46 67 680 0.2858 1.15 0.892,1.47 65 640
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.8185 1.01 0.939,1.08 816 8155 0.3221 0.88 0.683,1.13 59 561
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.4875 1.03 0.954,1.1 775 7756 0.8147 1.01 0.936,1.09 736 7482
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.2838 0.871 0.676,1.12 59 589 0.3221 0.88 0.683,1.13 59 561
226 Benign neoplasm of thyroid glands neoplasms Both 0.5794 1.04 0.915,1.17 266 2664 0.6237 1.03 0.909,1.17 255 2581
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.1236 1.06 0.985,1.13 861 8635 0.6592 0.974 0.864,1.1 295 2993
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.5152 1.05 0.904,1.22 186 1857 0.7379 1.03 0.88,1.2 178 1782
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.04169 1.12 1.0,1.24 371 3709 0.02138 1.14 1.02,1.27 350 3573
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.6486 0.973 0.866,1.09 309 3114 0.6592 0.974 0.864,1.1 295 2993
228 Hemangioma and lymphangioma, any site neoplasms Both 0.4677 1.02 0.968,1.07 1596 15966 0.6745 1.01 0.959,1.07 1462 15403
229 Benign neoplasm of unspecified sites neoplasms Both 0.4864 1.02 0.973,1.06 2397 23955 0.4688 0.984 0.941,1.03 2100 23224
860 Bone marrow or stem cell transplant neoplasms Both 0.1607 0.839 0.657,1.07 68 680 0.1722 0.837 0.649,1.08 62 662
240 Simple and unspecified goiter endocrine/metabolic Both 0.2667 0.954 0.878,1.04 600 6016 0.3133 0.957 0.88,1.04 569 5799
241 Nontoxic nodular goiter endocrine/metabolic Both 0.673 1.01 0.952,1.08 1107 11092 0.1019 1.07 0.986,1.16 631 6534
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.5248 0.97 0.882,1.07 471 4706 0.3491 0.954 0.866,1.05 442 4527
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.09333 1.07 0.989,1.16 676 6784 0.1019 1.07 0.986,1.16 631 6534
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.881 0.996 0.95,1.05 1854 18531 0.5534 1.06 0.882,1.26 135 1338
242.1 Graves' disease endocrine/metabolic Both 0.4315 0.962 0.873,1.06 456 4553 0.3837 0.957 0.867,1.06 436 4416
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.5 0.929 0.75,1.15 91 910 0.4898 0.927 0.748,1.15 90 887
242.3 Exophthalmos endocrine/metabolic Both 0.5689 1.05 0.881,1.26 138 1379 0.5534 1.06 0.882,1.26 135 1338
244 Hypothyroidism endocrine/metabolic Both 0.7798 0.998 0.981,1.01 14590 145053 0.7194 0.997 0.979,1.01 13343 133846
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.9528 0.998 0.938,1.06 1108 11079 0.975 0.999 0.937,1.07 1034 10691
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.3192 1.11 0.905,1.36 101 1010 0.2523 1.13 0.917,1.39 96 965
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.6699 0.996 0.979,1.01 13918 138926 0.7194 0.997 0.979,1.01 13343 133846
245 Thyroiditis endocrine/metabolic Both 0.3467 0.944 0.838,1.06 288 2877 0.4732 0.95 0.825,1.09 205 2027
245.2 Chronic thyroiditis endocrine/metabolic Both 0.5902 0.963 0.841,1.1 218 2177 0.4732 0.95 0.825,1.09 205 2027
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.5035 0.954 0.831,1.1 210 2097 0.4732 0.95 0.825,1.09 205 2027
246 Other disorders of thyroid endocrine/metabolic Both 0.2286 0.938 0.845,1.04 397 3975 0.2244 0.936 0.841,1.04 376 3821
250 Diabetes mellitus endocrine/metabolic Both 4.898E-4 1.03 1.01,1.04 19787 186006 0.2275 0.964 0.909,1.02 1268 12749
250.1 Type 1 diabetes endocrine/metabolic Both 0.2716 1.02 0.983,1.06 2758 27621 0.6501 1.04 0.882,1.22 156 1546
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.3999 0.944 0.825,1.08 239 2389 0.389 0.942 0.822,1.08 233 2312
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.4102 1.11 0.87,1.4 76 770 0.3365 1.13 0.883,1.44 74 743
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.1726 0.936 0.851,1.03 473 4744 0.1718 0.935 0.849,1.03 461 4547
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.8147 1.02 0.868,1.2 160 1610 0.6501 1.04 0.882,1.22 156 1546
250.2 Type 2 diabetes endocrine/metabolic Both 0.001413 1.03 1.01,1.04 17831 170202 0.302 1.05 0.957,1.15 479 4844
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.1019 1.19 0.967,1.46 104 1050 0.0955 1.2 0.969,1.48 99 1010
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.6012 0.962 0.831,1.11 200 2018 0.5675 0.957 0.824,1.11 192 1926
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.6237 0.983 0.92,1.05 986 9907 0.542 0.979 0.914,1.05 934 9450
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.2805 1.05 0.96,1.15 503 5066 0.302 1.05 0.957,1.15 479 4844
250.4 Abnormal glucose endocrine/metabolic Both 0.4624 1.03 0.953,1.11 680 6827 0.7396 1.02 0.92,1.13 400 4026
250.41 Impaired fasting glucose endocrine/metabolic Both 0.2793 1.07 0.945,1.22 265 2659 0.1936 1.09 0.957,1.24 248 2537
250.42 Other abnormal glucose endocrine/metabolic Both 0.9204 1.01 0.911,1.11 416 4178 0.7396 1.02 0.92,1.13 400 4026
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.9616 0.996 0.83,1.19 131 1308 0.9772 0.997 0.83,1.2 130 1269
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.6982 1.02 0.916,1.14 349 3495 0.6637 1.03 0.916,1.15 333 3358
250.7 Diabetic retinopathy endocrine/metabolic Both 0.3105 0.971 0.916,1.03 1329 13335 0.2275 0.964 0.909,1.02 1268 12749
251.1 Hypoglycemia endocrine/metabolic Both 0.7129 0.987 0.922,1.06 932 9370 0.9226 0.997 0.93,1.07 898 8982
252 Disorders of parathyroid gland endocrine/metabolic Both 0.1042 1.06 0.988,1.14 873 8719 0.4467 1.07 0.896,1.28 131 1373
252.1 Hyperparathyroidism endocrine/metabolic Both 0.1507 1.06 0.98,1.14 781 7802 0.07586 1.07 0.993,1.16 729 7509
252.2 Hypoparathyroidism endocrine/metabolic Both 0.6966 1.03 0.871,1.23 142 1418 0.4467 1.07 0.896,1.28 131 1373
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.3673 1.04 0.958,1.12 681 6821 0.3228 1.09 0.922,1.28 151 1502
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.826 0.983 0.845,1.14 187 1867 0.5047 0.93 0.75,1.15 89 908
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.8974 0.987 0.801,1.21 95 949 0.5047 0.93 0.75,1.15 89 908
253.2 Pituitary hypofunction endocrine/metabolic Both 0.08511 1.12 0.984,1.28 260 2618 0.1271 1.11 0.971,1.27 245 2530
253.3 Diabetes insipidus endocrine/metabolic Both 0.2761 0.885 0.711,1.1 92 919 0.2818 0.885 0.708,1.11 90 889
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.695 1.03 0.879,1.21 158 1578 0.3228 1.09 0.922,1.28 151 1502
255 Disorders of adrenal glands endocrine/metabolic Both 0.3707 0.963 0.886,1.05 638 6374 0.08318 0.904 0.807,1.01 342 3490
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.6966 1.03 0.884,1.2 180 1797 0.1858 1.18 0.923,1.51 72 734
255.11 Cushing's syndrome endocrine/metabolic Both 0.8954 0.986 0.805,1.21 103 1029 0.875 0.984 0.801,1.21 99 993
255.12 Hyperaldosteronism endocrine/metabolic Both 0.257 1.15 0.904,1.46 76 759 0.1858 1.18 0.923,1.51 72 734
255.2 Adrenal hypofunction endocrine/metabolic Both 0.1247 0.917 0.822,1.02 362 3617 0.08318 0.904 0.807,1.01 342 3490
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.1112 0.914 0.819,1.02 361 3607 0.08318 0.904 0.807,1.01 342 3490
256 Ovarian dysfunction endocrine/metabolic Female 0.7798 1.02 0.891,1.17 240 2397 0.7031 1.03 0.89,1.19 204 2062
256.4 Polycystic ovaries endocrine/metabolic Female 0.7228 1.03 0.889,1.18 209 2088 0.7031 1.03 0.89,1.19 204 2062
257 Testicular dysfunction endocrine/metabolic Male 0.2582 1.1 0.933,1.29 160 1619 0.4345 1.07 0.904,1.26 143 1483
257.1 Testicular hypofunction endocrine/metabolic Male 0.3499 1.08 0.918,1.27 152 1539 0.4345 1.07 0.904,1.26 143 1483
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.4416 1.08 0.885,1.32 102 1020 0.3715 1.1 0.894,1.35 99 972
259 Other endocrine disorders endocrine/metabolic Both 0.0955 1.15 0.975,1.36 149 1498 0.1259 1.14 0.964,1.35 144 1448
260 Protein-calorie malnutrition endocrine/metabolic Both 0.3908 1.07 0.921,1.23 202 2018 0.4932 1.03 0.954,1.1 785 8013
260.1 Cachexia endocrine/metabolic Both 0.6998 0.947 0.718,1.25 51 510 ,
260.6 Anorexia endocrine/metabolic Both 0.4645 1.03 0.956,1.1 830 8317 0.4932 1.03 0.954,1.1 785 8013
261 Vitamin deficiency endocrine/metabolic Both 0.7096 0.989 0.931,1.05 1199 11974 0.5916 0.938 0.742,1.19 73 739
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.8492 1.01 0.935,1.09 755 7541 0.9268 1.0 0.93,1.08 724 7251
261.4 Vitamin D deficiency endocrine/metabolic Both 0.5023 0.967 0.876,1.07 447 4462 0.5916 0.938 0.742,1.19 73 739
261.41 Rickets or osteomalacia endocrine/metabolic Both 0.5916 0.939 0.748,1.18 77 769 0.5916 0.938 0.742,1.19 73 739
262 Mineral deficiency NEC endocrine/metabolic Both 0.3296 1.07 0.936,1.22 241 2407 0.2028 1.09 0.954,1.25 232 2331
269 Proteinuria endocrine/metabolic Both 0.3273 1.06 0.944,1.19 338 3378 0.2133 1.08 0.958,1.21 324 3241
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.1734 1.08 0.965,1.22 303 3028 0.8204 0.97 0.745,1.26 57 659
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.1698 1.09 0.964,1.23 261 2608 0.8204 0.97 0.745,1.26 57 659
270.32 Paraproteinemia endocrine/metabolic Both 0.1486 1.11 0.963,1.28 191 1910 0.2371 1.09 0.943,1.27 179 1803
270.33 Amyloidosis endocrine/metabolic Both 0.3681 1.1 0.898,1.34 113 1129 0.4797 1.08 0.878,1.32 108 1078
270.35 Macroglobulinemia endocrine/metabolic Both 0.9099 0.986 0.771,1.26 69 689 0.8204 0.97 0.745,1.26 57 659
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.1282 0.882 0.75,1.04 160 1600 0.2897 0.907 0.758,1.09 129 1341
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.3062 0.913 0.767,1.09 139 1391 0.2897 0.907 0.758,1.09 129 1341
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.01202 1.01 1.0,1.03 34835 235433 0.9247 1.01 0.868,1.17 196 2023
272.1 Hyperlipidemia endocrine/metabolic Both 0.01288 1.01 1.0,1.03 34764 235203 0.1014 0.873 0.742,1.03 159 1578
272.11 Hypercholesterolemia endocrine/metabolic Both 0.02089 1.01 1.0,1.03 32324 228083 0.0309 1.01 1.0,1.03 30544 219659
272.12 Hyperglyceridemia endocrine/metabolic Both 0.5808 1.08 0.822,1.42 58 580 0.6368 1.07 0.812,1.4 57 544
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.2113 0.903 0.769,1.06 164 1637 0.1014 0.873 0.742,1.03 159 1578
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.6653 1.03 0.894,1.19 211 2109 0.9247 1.01 0.868,1.17 196 2023
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.3673 1.02 0.982,1.05 3724 37231 0.236 1.06 0.966,1.15 537 5354
274.1 Gout endocrine/metabolic Both 0.5821 1.01 0.974,1.05 3171 31705 0.6839 0.96 0.787,1.17 107 1079
274.11 Gouty arthropathy endocrine/metabolic Both 0.8318 0.979 0.806,1.19 112 1119 0.6839 0.96 0.787,1.17 107 1079
274.2 Crystal arthropathies endocrine/metabolic Both 0.2729 1.05 0.964,1.14 613 6124 0.236 1.06 0.966,1.15 537 5354
274.21 Chondrocalcinosis endocrine/metabolic Both 0.2553 1.05 0.964,1.15 558 5576 0.236 1.06 0.966,1.15 537 5354
275 Disorders of mineral metabolism endocrine/metabolic Both 0.2138 1.03 0.984,1.08 2107 21070 0.9419 1.0 0.924,1.09 617 6267
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.1644 1.08 0.97,1.2 375 3745 0.2118 1.07 0.961,1.2 345 3594
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.2818 1.03 0.974,1.1 1202 12019 0.2317 1.11 0.937,1.31 157 1643
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.1507 1.13 0.958,1.32 171 1717 0.2317 1.11 0.937,1.31 157 1643
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.207 1.02 0.991,1.04 7284 72932 0.673 0.962 0.806,1.15 122 1245
276.1 Electrolyte imbalance endocrine/metabolic Both 0.07586 1.03 0.997,1.06 4086 40930 0.5129 1.02 0.964,1.08 1341 13659
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.8017 1.02 0.889,1.16 239 2409 0.8091 1.02 0.886,1.17 230 2304
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.2506 1.03 0.98,1.08 1818 18200 0.3221 1.03 0.976,1.08 1733 17384
276.13 Hyperpotassemia endocrine/metabolic Both 0.05754 1.07 0.998,1.14 969 9728 0.1603 1.05 0.981,1.13 904 9281
276.14 Hypopotassemia endocrine/metabolic Both 0.4083 1.02 0.969,1.08 1424 14235 0.5129 1.02 0.964,1.08 1341 13659
276.4 Acid-base balance disorder endocrine/metabolic Both 0.5321 1.02 0.96,1.08 1161 11629 0.7691 0.972 0.801,1.18 108 1080
276.41 Acidosis endocrine/metabolic Both 0.5495 1.02 0.957,1.09 1056 10577 0.3981 1.03 0.964,1.1 1002 10127
276.42 Alkalosis endocrine/metabolic Both 0.8472 0.982 0.813,1.18 113 1129 0.7691 0.972 0.801,1.18 108 1080
276.5 Hypovolemia endocrine/metabolic Both 0.4581 1.01 0.976,1.06 2827 28265 0.5035 1.01 0.974,1.06 2682 27012
276.6 Fluid overload endocrine/metabolic Both 0.7674 0.985 0.894,1.09 451 4535 0.6699 0.978 0.883,1.08 413 4323
276.8 Polydipsia endocrine/metabolic Both 0.8974 0.989 0.83,1.18 128 1278 0.673 0.962 0.806,1.15 122 1245
277 Other disorders of metabolism endocrine/metabolic Both 0.7621 0.989 0.924,1.06 899 8977 0.08511 1.13 0.983,1.3 219 2196
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.06607 1.11 0.993,1.24 362 3613 0.07762 1.11 0.989,1.24 353 3448
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.05888 1.14 0.995,1.31 230 2298 0.08511 1.13 0.983,1.3 219 2196
277.51 Lipoprotein disorders endocrine/metabolic Both 0.2427 1.18 0.892,1.57 52 520 ,
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.1276 1.02 0.996,1.04 10804 108289 0.6223 1.06 0.833,1.36 62 632
278.1 Obesity endocrine/metabolic Both 0.09333 1.02 0.997,1.04 10642 106670 0.09333 1.02 0.997,1.04 10226 102920
278.3 Localized adiposity endocrine/metabolic Both 0.5929 0.94 0.75,1.18 84 838 0.4083 0.907 0.72,1.14 80 818
278.4 Abnormal weight gain endocrine/metabolic Both 0.5861 1.07 0.843,1.35 66 660 0.6223 1.06 0.833,1.36 62 632
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.7816 0.982 0.86,1.12 250 2510 0.7211 1.02 0.898,1.17 237 2373
279.1 Immunity deficiency endocrine/metabolic Both 0.9572 1.0 0.87,1.16 209 2100 0.278 0.905 0.755,1.08 130 1341
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.2344 0.899 0.754,1.07 138 1390 0.278 0.905 0.755,1.08 130 1341
279.7 Other immunological findings endocrine/metabolic Both 0.8551 1.01 0.891,1.15 248 2478 0.7211 1.02 0.898,1.17 237 2373
275.1 Disorders of iron metabolism hematopoietic Both 0.7362 1.01 0.936,1.1 653 6535 0.9419 1.0 0.924,1.09 617 6267
280 Iron deficiency anemias hematopoietic Both 0.004169 1.04 1.01,1.06 7610 76168 0.02818 1.12 1.01,1.23 433 4406
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.005012 1.04 1.01,1.06 7311 73153 0.007762 1.03 1.01,1.06 6958 70465
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.03467 1.11 1.01,1.22 452 4541 0.02818 1.12 1.01,1.23 433 4406
281 Other deficiency anemia hematopoietic Both 0.06761 1.06 0.996,1.13 1112 11126 0.871 0.978 0.748,1.28 52 519
281.1 Megaloblastic anemia hematopoietic Both 0.0537 1.06 0.999,1.13 1066 10669 0.5675 0.955 0.817,1.12 175 1753
281.11 Pernicious anemia hematopoietic Both 0.0389 1.08 1.0,1.17 750 7514 0.01778 1.1 1.02,1.18 723 7224
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.5117 1.05 0.9,1.24 177 1769 0.507 1.06 0.898,1.24 167 1711
281.13 Folate-deficiency anemia hematopoietic Both 0.6871 0.969 0.831,1.13 183 1836 0.5675 0.955 0.817,1.12 175 1753
281.9 Deficiency anemias hematopoietic Both 0.7907 0.965 0.742,1.26 54 538 0.871 0.978 0.748,1.28 52 519
282 Hereditary hemolytic anemias hematopoietic Both 0.673 1.04 0.876,1.23 150 1499 0.2985 1.12 0.902,1.4 84 819
282.8 Other hemoglobinopathies hematopoietic Both 0.9397 0.99 0.751,1.3 56 560 0.9817 1.0 0.759,1.33 55 543
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.3141 1.12 0.899,1.39 85 849 0.2985 1.12 0.902,1.4 84 819
283 Acquired hemolytic anemias hematopoietic Both 0.9247 0.992 0.834,1.18 135 1377 0.3221 1.11 0.903,1.36 97 1016
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.4295 1.08 0.887,1.33 103 1059 0.3221 1.11 0.903,1.36 97 1016
284 Aplastic anemia hematopoietic Both 0.4207 1.04 0.944,1.15 435 4357 0.5598 1.03 0.931,1.14 399 4164
285 Other anemias hematopoietic Both 5.495E-4 1.03 1.01,1.05 12104 121094 0.1968 1.07 0.965,1.19 389 3980
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.1459 0.912 0.805,1.03 271 2707 0.07413 0.889 0.782,1.01 255 2619
285.2 Anemia of chronic disease hematopoietic Both 0.4853 1.03 0.951,1.11 697 6980 0.1968 1.07 0.965,1.19 389 3980
285.22 Anemia in neoplastic disease hematopoietic Both 0.1236 1.08 0.979,1.2 414 4147 0.1968 1.07 0.965,1.19 389 3980
286 Coagulation defects hematopoietic Both 0.413 1.03 0.961,1.1 921 9218 0.5546 1.03 0.929,1.15 370 3735
286.1 Congenital coagulation defects hematopoietic Both 0.5572 1.03 0.935,1.13 459 4594 0.07079 1.27 0.981,1.64 62 603
286.11 Von willebrand's disease hematopoietic Both 0.3664 0.905 0.729,1.12 96 959 0.4009 0.911 0.732,1.13 93 923
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.5236 1.04 0.922,1.17 294 2944 0.5495 1.04 0.919,1.17 283 2850
286.13 Congenital factor VIII disorder hematopoietic Both 0.05754 1.28 0.993,1.65 63 630 0.07079 1.27 0.981,1.64 62 603
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.857 0.98 0.787,1.22 86 860 0.9311 1.01 0.807,1.26 81 822
286.7 Other and unspecified coagulation defects hematopoietic Both 0.3243 1.05 0.95,1.17 386 3867 0.5546 1.03 0.929,1.15 370 3735
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.8222 0.994 0.946,1.05 1652 16532 0.8872 1.02 0.815,1.27 73 729
287.1 Spontaneous ecchymoses hematopoietic Both 0.857 1.02 0.852,1.21 129 1290 0.778 1.03 0.855,1.23 121 1241
287.2 Allergic purpura hematopoietic Both 0.5821 0.922 0.692,1.23 51 510 ,
287.3 Thrombocytopenia hematopoietic Both 0.7691 0.992 0.942,1.04 1553 15543 0.8872 1.02 0.815,1.27 73 729
287.31 Primary thrombocytopenia hematopoietic Both 0.1507 1.08 0.974,1.19 419 4195 0.2223 1.07 0.962,1.18 389 4017
287.32 Secondary thrombocytopenia hematopoietic Both 0.8414 1.02 0.821,1.27 75 749 0.8872 1.02 0.815,1.27 73 729
288 Diseases of white blood cells hematopoietic Both 0.492 0.988 0.956,1.02 3765 37672 0.6209 1.06 0.835,1.35 68 682
288.1 Decreased white blood cell count hematopoietic Both 0.2576 0.979 0.944,1.02 3168 31704 0.2065 0.976 0.94,1.01 2976 30557
288.11 Neutropenia hematopoietic Both 0.2799 0.98 0.945,1.02 3176 31784 0.2065 0.976 0.94,1.01 2976 30557
288.3 Eosinophilia hematopoietic Both 0.6295 1.06 0.838,1.34 71 709 0.6209 1.06 0.835,1.35 68 682
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.455 1.03 0.957,1.1 862 8625 0.3733 1.1 0.889,1.37 85 858
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.9506 1.0 0.89,1.13 290 2897 0.7464 1.02 0.902,1.15 276 2782
289.4 Lymphadenitis hematopoietic Both 0.0309 1.05 1.0,1.09 2602 26061 0.06761 1.04 0.997,1.08 2435 25074
289.5 Diseases of spleen hematopoietic Both 0.5248 0.971 0.888,1.06 516 5153 0.5176 0.97 0.884,1.06 482 4939
289.8 Polycythemia, secondary hematopoietic Both 0.03981 1.14 1.01,1.28 292 2917 0.07244 1.12 0.99,1.27 280 2803
289.9 Abnormality of red blood cells hematopoietic Both 0.3499 1.1 0.897,1.36 90 900 0.3733 1.1 0.889,1.37 85 858
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.03311 1.05 1.0,1.1 1929 19281 0.955 1.01 0.786,1.29 68 691
290.1 Dementias mental disorders Both 0.09333 1.06 0.991,1.13 1004 10032 0.2377 1.09 0.943,1.27 186 1895
290.11 Alzheimer's disease mental disorders Both 0.03548 1.11 1.01,1.23 431 4307 0.01288 1.14 1.03,1.27 406 4090
290.16 Vascular dementia mental disorders Both 0.3581 1.07 0.927,1.23 201 2008 0.2377 1.09 0.943,1.27 186 1895
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.3882 1.04 0.956,1.12 650 6501 0.2838 1.05 0.963,1.14 620 6201
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.8472 0.977 0.766,1.25 70 709 0.955 1.01 0.786,1.29 68 691
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.1538 1.05 0.981,1.13 836 8385 0.0537 1.1 0.999,1.22 417 4232
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.25 0.901 0.754,1.08 132 1320 0.3062 0.911 0.762,1.09 130 1284
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.4467 1.05 0.927,1.19 286 2867 0.673 1.03 0.905,1.17 273 2747
291.8 Alteration of consciousness mental disorders Both 0.03715 1.11 1.01,1.23 436 4376 0.0537 1.1 0.999,1.22 417 4232
292 Neurological disorders mental disorders Both 0.2296 1.02 0.988,1.05 4621 46260 0.335 1.06 0.942,1.19 291 2961
292.1 Aphasia/speech disturbance mental disorders Both 0.4335 1.02 0.968,1.08 1504 15074 0.4276 1.02 0.968,1.08 1439 14469
292.2 Mild cognitive impairment mental disorders Both 0.9078 1.01 0.868,1.17 190 1907 0.7962 0.98 0.84,1.14 180 1825
292.3 Memory loss mental disorders Both 0.1919 1.05 0.974,1.14 696 6978 0.1972 1.05 0.973,1.14 666 6697
292.4 Altered mental status mental disorders Both 0.7834 1.01 0.963,1.05 2181 21827 0.7962 1.01 0.961,1.05 2087 20833
292.6 Hallucinations mental disorders Both 0.4385 1.05 0.934,1.17 307 3073 0.335 1.06 0.942,1.19 291 2961
293 Symptoms involving head and neck mental disorders Both 0.537 1.01 0.97,1.06 2078 20779 0.8147 1.01 0.94,1.08 837 8670
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.6412 1.02 0.95,1.09 901 9010 0.8147 1.01 0.94,1.08 837 8670
295 Schizophrenia and other psychotic disorders mental disorders Both 0.8166 0.992 0.924,1.06 841 8446 0.335 0.927 0.794,1.08 164 1655
295.1 Schizophrenia mental disorders Both 0.6808 0.982 0.901,1.07 574 5766 0.8375 0.991 0.909,1.08 564 5612
295.2 Paranoid disorders mental disorders Both 0.7816 1.02 0.881,1.18 178 1780 0.6918 1.03 0.888,1.2 177 1721
295.3 Psychosis mental disorders Both 0.3681 0.932 0.799,1.09 169 1710 0.335 0.927 0.794,1.08 164 1655
296 Mood disorders mental disorders Both 0.2582 1.01 0.992,1.03 12372 123822 0.4592 1.04 0.935,1.16 346 3487
296.1 Bipolar mental disorders Both 0.9311 1.0 0.941,1.07 1059 10599 0.7638 1.01 0.947,1.08 1025 10309
296.2 Depression mental disorders Both 0.3365 1.01 0.99,1.03 11737 117469 0.4592 1.04 0.935,1.16 346 3487
296.22 Major depressive disorder mental disorders Both 0.4742 1.04 0.935,1.16 361 3604 0.4592 1.04 0.935,1.16 346 3487
297.2 Suicide or self-inflicted injury mental disorders Both 0.1742 0.924 0.824,1.04 311 3070 0.2291 0.931 0.83,1.05 302 2990
300 Anxiety disorders mental disorders Both 0.8222 1.0 0.978,1.03 6844 68484 0.7943 0.975 0.809,1.18 112 1099
300.1 Anxiety disorder mental disorders Both 0.8185 1.0 0.977,1.03 6324 63282 0.9931 1.0 0.909,1.1 485 4835
300.11 Generalized anxiety disorder mental disorders Both 0.9683 0.997 0.842,1.18 149 1499 0.9226 1.01 0.847,1.2 141 1451
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.455 0.971 0.899,1.05 707 7065 0.271 0.957 0.885,1.03 684 6830
300.13 Phobia mental disorders Both 0.7499 1.02 0.925,1.11 501 5013 0.9931 1.0 0.909,1.1 485 4835
300.3 Obsessive-compulsive disorders mental disorders Both 0.8356 1.02 0.855,1.21 140 1407 0.7499 1.03 0.862,1.23 137 1366
300.4 Dysthymic disorder mental disorders Both 0.3828 1.13 0.86,1.48 53 530 0.3631 1.13 0.864,1.49 52 514
300.8 Acute reaction to stress mental disorders Both 0.1963 1.13 0.939,1.36 124 1238 0.1384 1.15 0.956,1.38 123 1204
300.9 Posttraumatic stress disorder mental disorders Both 0.7499 0.97 0.805,1.17 113 1129 0.7943 0.975 0.809,1.18 112 1099
301 Personality disorders mental disorders Both 0.06918 1.11 0.992,1.25 334 3338 0.7586 0.971 0.807,1.17 116 1160
301.2 Antisocial/borderline personality disorder mental disorders Both 0.9057 0.989 0.823,1.19 119 1186 0.7586 0.971 0.807,1.17 116 1160
302 Sexual and gender identity disorders mental disorders Both 0.415 1.05 0.93,1.19 283 2845 0.5521 1.04 0.916,1.18 272 2718
303 Psychogenic and somatoform disorders mental disorders Both 0.2208 1.06 0.965,1.17 467 4679 0.0912 1.17 0.974,1.41 118 1193
303.3 Psychogenic disorder mental disorders Both 0.4592 1.04 0.934,1.16 350 3510 0.5395 1.04 0.926,1.16 339 3400
303.4 Somatoform disorder mental disorders Both 0.08511 1.17 0.978,1.41 123 1229 0.0912 1.17 0.974,1.41 118 1193
304 Adjustment reaction mental disorders Both 0.3681 1.06 0.937,1.19 293 2936 0.3304 1.06 0.94,1.2 286 2875
305.2 Eating disorder mental disorders Both 0.984 0.998 0.813,1.22 90 900 0.8054 0.974 0.79,1.2 86 887
306 Other mental disorder mental disorders Both 0.008913 1.02 1.0,1.03 28056 230087 0.335 1.06 0.942,1.19 305 3045
306.9 Tension headache mental disorders Both 0.4819 1.04 0.928,1.17 315 3148 0.335 1.06 0.942,1.19 305 3045
313 Pervasive developmental disorders mental disorders Both 0.3631 0.898 0.712,1.13 76 770 0.8892 0.98 0.739,1.3 53 528
313.3 Autism mental disorders Both 0.8492 0.973 0.734,1.29 53 539 0.8892 0.98 0.739,1.3 53 528
315 Develomental delays and disorders mental disorders Both 0.1991 0.932 0.838,1.04 351 3517 0.9931 0.999 0.802,1.24 86 840
315.1 Learning disorder mental disorders Both 0.2399 1.1 0.938,1.29 161 1610 0.2075 1.11 0.943,1.31 153 1568
315.2 Speech and language disorder mental disorders Both 0.867 0.982 0.79,1.22 88 880 0.9931 0.999 0.802,1.24 86 840
316 Substance addiction and disorders mental disorders Both 0.007762 1.04 1.01,1.07 5313 53131 0.5346 1.09 0.828,1.44 56 575
316.1 Polyneuropathy due to drugs mental disorders Both 0.4083 1.12 0.855,1.47 60 599 0.5346 1.09 0.828,1.44 56 575
317 Alcohol-related disorders mental disorders Both 0.004677 1.03 1.01,1.05 12696 126892 0.1799 1.05 0.977,1.13 813 8095
317.1 Alcoholism mental disorders Both 0.04571 1.02 1.0,1.05 8890 88923 0.1799 1.05 0.977,1.13 813 8095
317.11 Alcoholic liver damage mental disorders Both 0.207 1.05 0.975,1.13 838 8392 0.1799 1.05 0.977,1.13 813 8095
318 Tobacco use disorder mental disorders Both 0.01148 1.02 1.0,1.03 19359 185465 0.009772 1.02 1.0,1.04 18606 179029
320 Meningitis neurological Both 0.9226 0.995 0.901,1.1 444 4447 0.8511 0.99 0.895,1.1 428 4296
323 Encephalitis neurological Both 0.0955 0.912 0.818,1.02 342 3422 0.05888 0.795 0.626,1.01 73 718
323.2 Acute (transverse) myelitis neurological Both 0.0537 0.792 0.625,1.0 74 739 0.05888 0.795 0.626,1.01 73 718
324 Other CNS infection and poliomyelitis neurological Both 0.4977 1.04 0.924,1.18 292 2916 0.6026 1.03 0.913,1.17 279 2787
327 Sleep disorders neurological Both 0.6209 0.985 0.927,1.05 1164 11659 0.6699 0.959 0.79,1.16 122 1333
327.3 Sleep apnea neurological Both 0.1656 1.02 0.991,1.05 4428 44318 0.2698 1.02 0.986,1.05 4252 42671
327.4 Insomnia neurological Both 0.7063 0.969 0.82,1.14 163 1660 0.6699 0.959 0.79,1.16 122 1333
327.41 Organic or persistent insomnia neurological Both 0.5333 0.944 0.787,1.13 136 1390 0.6699 0.959 0.79,1.16 122 1333
331 Other cerebral degenerations neurological Both 0.7998 0.992 0.933,1.06 1142 11416 0.9572 0.997 0.9,1.11 408 4112
331.1 Hydrocephalus neurological Both 0.9333 1.0 0.916,1.1 502 5014 0.9683 0.998 0.909,1.1 481 4830
331.9 Cerebral degeneration, unspecified neurological Both 0.875 1.01 0.912,1.11 430 4298 0.9572 0.997 0.9,1.11 408 4112
332 Parkinson's disease neurological Both 0.4977 1.02 0.96,1.09 1126 11254 0.5236 1.02 0.957,1.09 1033 10688
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.5741 1.02 0.952,1.09 894 8954 0.6592 0.97 0.849,1.11 239 2420
333.1 Essential tremor neurological Both 0.5998 1.04 0.903,1.19 216 2157 0.826 0.984 0.851,1.14 197 2057
333.2 Myoclonus neurological Both 0.4102 0.913 0.734,1.13 96 958 0.263 0.881 0.707,1.1 93 922
333.4 Torsion dystonia neurological Both 0.7228 0.977 0.859,1.11 253 2528 0.6592 0.97 0.849,1.11 239 2420
334 Degenerative disease of the spinal cord neurological Both 0.5781 1.01 0.966,1.06 1812 18130 0.2979 0.93 0.812,1.07 234 2343
334.1 Spinocerebellar disease neurological Both 0.8375 0.981 0.815,1.18 117 1169 0.8995 0.988 0.816,1.2 111 1128
334.2 Anterior horn cell disease neurological Both 0.2767 0.929 0.813,1.06 245 2446 0.2979 0.93 0.812,1.07 234 2343
335 Multiple sclerosis neurological Both 0.4667 0.98 0.927,1.04 1340 13385 0.5649 0.984 0.929,1.04 1294 12970
337 Disorders of the autonomic nervous system neurological Both 0.6252 1.03 0.91,1.17 266 2668 0.984 0.998 0.783,1.27 69 681
337.1 Peripheral autonomic neuropathy neurological Both 0.8933 1.02 0.804,1.28 72 719 0.984 0.998 0.783,1.27 69 681
338 Pain neurological Both 0.6902 0.985 0.915,1.06 768 7692 0.6109 1.03 0.924,1.14 365 3691
338.1 Acute pain neurological Both 0.2944 0.947 0.855,1.05 394 3937 0.369 0.953 0.857,1.06 371 3788
338.2 Chronic pain neurological Both 0.6871 1.02 0.92,1.14 380 3817 0.6109 1.03 0.924,1.14 365 3691
339 Other headache syndromes neurological Both 0.06607 1.02 0.999,1.05 7819 78241 0.1517 1.02 0.994,1.04 7554 75796
340 Migraine neurological Both 0.1875 1.03 0.987,1.07 2860 28602 0.6368 0.966 0.837,1.11 209 2057
340.1 Migrain with aura neurological Both 0.5445 0.957 0.83,1.1 212 2117 0.6368 0.966 0.837,1.11 209 2057
341 Other demyelinating diseases of central nervous system neurological Both 0.7586 0.98 0.861,1.12 252 2535 0.6871 0.974 0.854,1.11 249 2465
342 Hemiplegia neurological Both 0.3404 0.974 0.924,1.03 1494 14947 0.2667 0.97 0.918,1.02 1429 14345
343 Infantile cerebral palsy neurological Both 0.7534 1.03 0.866,1.22 145 1450 0.4365 1.07 0.9,1.28 141 1414
344 Other paralytic syndromes neurological Both 0.2339 1.05 0.969,1.14 658 6593 0.1368 1.06 0.981,1.15 635 6332
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.7638 0.996 0.967,1.03 5023 50270 0.8492 0.996 0.952,1.04 2142 21515
345.1 Epilepsy neurological Both 0.9817 1.0 0.934,1.07 866 8661 0.8433 1.01 0.896,1.14 270 2678
345.11 Generalized convulsive epilepsy neurological Both 0.7998 1.01 0.918,1.12 439 4385 0.7379 1.02 0.92,1.12 422 4237
345.12 Partial epilepsy neurological Both 0.8091 1.01 0.9,1.14 277 2776 0.8433 1.01 0.896,1.14 270 2678
345.3 Convulsions neurological Both 0.8933 0.997 0.954,1.04 2235 22339 0.8492 0.996 0.952,1.04 2142 21515
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.4808 0.942 0.798,1.11 144 1438 0.6699 0.964 0.813,1.14 136 1372
348 Other conditions of brain neurological Both 0.1514 1.05 0.981,1.13 778 7808 0.09772 1.09 0.984,1.21 363 3750
348.2 Cerebral edema and compression of brain neurological Both 0.2559 1.07 0.95,1.21 268 2678 0.3221 1.06 0.941,1.2 260 2584
348.4 Cerebral cysts neurological Both 0.2698 1.11 0.925,1.32 133 1350 0.2344 1.12 0.93,1.34 130 1309
348.7 Coma neurological Both 0.5998 1.03 0.924,1.15 358 3596 0.4887 1.04 0.931,1.16 346 3458
348.8 Encephalopathy, not elsewhere classified neurological Both 0.975 1.0 0.88,1.14 249 2504 0.8954 0.991 0.868,1.13 239 2417
348.9 Other conditions of brain, NOS neurological Both 0.0631 1.1 0.995,1.22 390 3899 0.09772 1.09 0.984,1.21 363 3750
349 Other and unspecified disorders of the nervous system neurological Both 0.7328 0.981 0.878,1.1 342 3414 0.8128 0.986 0.881,1.1 326 3297
350 Abnormal movement neurological Both 0.1143 1.03 0.992,1.07 2671 26722 0.4102 0.892 0.679,1.17 52 516
350.1 Abnormal involuntary movements neurological Both 0.414 1.03 0.96,1.1 887 8852 0.3945 1.03 0.961,1.11 839 8471
350.2 Abnormality of gait neurological Both 0.06607 1.05 0.997,1.11 1596 15969 0.07244 1.05 0.996,1.11 1534 15228
350.3 Lack of coordination neurological Both 0.5821 0.971 0.873,1.08 363 3638 0.5333 0.966 0.866,1.08 344 3487
350.6 Disturbances of sensation of smell and taste neurological Both 0.6745 0.944 0.722,1.23 54 540 0.4102 0.892 0.679,1.17 52 516
351 Other peripheral nerve disorders neurological Both 0.1589 1.01 0.995,1.03 12420 124321 0.2799 1.01 0.992,1.03 11955 119916
352 Disorders of other cranial nerves neurological Both 0.03631 1.06 1.0,1.12 1370 13706 0.02818 1.08 1.01,1.16 834 8485
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.3133 1.05 0.955,1.16 463 4638 0.2831 1.05 0.957,1.16 444 4476
352.2 Facial nerve disorders [CN7] neurological Both 0.03981 1.08 1.0,1.15 880 8795 0.02818 1.08 1.01,1.16 834 8485
353 Nerve root and plexus disorders neurological Both 0.4276 0.976 0.917,1.04 1131 11319 0.1384 0.809 0.612,1.07 54 548
353.1 Nerve plexus lesions neurological Both 0.6561 0.959 0.796,1.15 114 1138 0.7962 0.975 0.807,1.18 109 1099
353.2 Nerve root lesions neurological Both 0.1928 0.833 0.632,1.1 57 570 0.1384 0.809 0.612,1.07 54 548
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.5248 0.949 0.808,1.11 152 1520 0.4487 0.939 0.797,1.11 147 1450
357 Inflammatory and toxic neuropathy neurological Both 0.1052 0.955 0.903,1.01 1361 13648 0.07079 0.949 0.896,1.0 1300 13076
358 Myoneural disorders neurological Both 0.3041 1.08 0.935,1.24 211 2109 0.0871 1.14 0.981,1.33 187 1837
358.1 Myasthenia gravis neurological Both 0.2104 1.1 0.947,1.28 192 1919 0.0871 1.14 0.981,1.33 187 1837
359 Muscular dystrophies and other myopathies neurological Both 0.1905 0.938 0.853,1.03 465 4646 0.4842 0.961 0.859,1.07 343 3464
359.1 Muscular dystrophies neurological Both 0.07762 0.848 0.706,1.02 122 1219 0.1194 0.862 0.715,1.04 118 1190
359.2 Myopathy neurological Both 0.3656 0.951 0.852,1.06 360 3597 0.4842 0.961 0.859,1.07 343 3464
360 Disorders of the globe sense organs Both 0.3459 1.06 0.943,1.18 337 3367 0.3266 1.07 0.936,1.22 243 2412
360.2 Progressive myopia sense organs Both 0.3767 1.06 0.931,1.21 251 2508 0.3266 1.07 0.936,1.22 243 2412
361 Retinal detachments and defects sense organs Both 0.03388 0.961 0.927,0.997 3246 32453 0.869 1.02 0.79,1.32 65 655
361.1 Retinal detachment with retinal defect sense organs Both 0.9376 1.0 0.948,1.06 1389 13884 0.6166 1.01 0.959,1.07 1335 13343
361.2 Retinoschisis and retinal cysts sense organs Both 0.871 1.02 0.793,1.31 68 680 0.869 1.02 0.79,1.32 65 655
362 Other retinal disorders sense organs Both 0.5309 1.01 0.978,1.04 3836 38370 0.5012 1.07 0.879,1.3 113 1114
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.6531 1.01 0.967,1.06 2182 21813 0.6808 1.01 0.965,1.06 2079 20742
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.6237 1.01 0.967,1.06 2179 21783 0.6808 1.01 0.965,1.06 2079 20742
362.3 Other nondiabetic retinopathy sense organs Both 0.4217 0.934 0.791,1.1 161 1609 0.2234 0.877 0.71,1.08 95 943
362.31 Separation of retinal layers sense organs Both 0.3873 0.913 0.742,1.12 99 990 0.2234 0.877 0.71,1.08 95 943
362.4 Retinal vascular changes and abnomalities sense organs Both 0.2698 1.04 0.97,1.12 848 8477 0.3606 1.03 0.963,1.11 818 8096
362.6 Peripheral retinal degenerations sense organs Both 0.984 1.0 0.861,1.16 182 1827 0.984 1.0 0.857,1.17 170 1750
362.7 Hereditary retinal dystrophies sense organs Both 0.9594 1.01 0.799,1.27 82 812 0.8995 1.02 0.804,1.28 80 782
362.8 Retinal hemorrhage/ischemia sense organs Both 0.5998 1.05 0.869,1.27 116 1159 0.5012 1.07 0.879,1.3 113 1114
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.3289 0.926 0.794,1.08 170 1699 0.208 0.859 0.678,1.09 64 662
363.3 Chorioretinal scars sense organs Both 0.171 0.854 0.681,1.07 69 690 0.208 0.859 0.678,1.09 64 662
364 Corneal opacity and other disorders of cornea sense organs Both 0.2275 0.952 0.878,1.03 647 6485 0.2223 1.14 0.924,1.4 96 957
364.1 Corneal opacity sense organs Both 0.4571 0.921 0.741,1.14 90 910 0.5728 0.938 0.75,1.17 85 874
364.2 Corneal edema sense organs Both 0.3532 0.901 0.723,1.12 79 800 0.2786 0.882 0.702,1.11 72 769
364.4 Corneal degenerations sense organs Both 0.8222 1.02 0.88,1.17 201 2017 0.9705 0.996 0.804,1.23 83 837
364.41 Keratoconus sense organs Both 0.865 0.982 0.795,1.21 86 869 0.9705 0.996 0.804,1.23 83 837
364.5 Corneal dystrophy sense organs Both 0.4198 1.06 0.919,1.23 211 2109 0.4436 1.06 0.912,1.23 195 2029
364.9 Cornea replaced by transplant sense organs Both 0.2518 1.13 0.918,1.39 100 1000 0.2223 1.14 0.924,1.4 96 957
365 Glaucoma sense organs Both 0.8356 0.997 0.966,1.03 4408 44136 0.5929 1.02 0.944,1.11 664 6679
365.1 Open-angle glaucoma sense organs Both 0.7129 1.01 0.949,1.08 1032 10346 0.618 1.02 0.952,1.09 961 9812
365.11 Primary open angle glaucoma sense organs Both 0.6053 1.02 0.954,1.08 1026 10287 0.618 1.02 0.952,1.09 961 9812
365.2 Primary angle-closure glaucoma sense organs Both 0.5408 1.02 0.948,1.11 698 6996 0.5929 1.02 0.944,1.11 664 6679
366 Cataract sense organs Both 0.6026 1.0 0.989,1.02 19926 168711 0.7379 0.967 0.792,1.18 99 982
366.1 Nonsenile Cataract sense organs Both 0.2588 1.15 0.902,1.47 69 700 0.302 1.14 0.89,1.45 68 674
366.2 Senile cataract sense organs Both 0.2259 1.01 0.991,1.04 8231 81909 0.1667 1.02 0.993,1.04 7791 77972
366.3 Traumatic cataract sense organs Both 0.618 0.952 0.784,1.16 102 1019 0.7379 0.967 0.792,1.18 99 982
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.9204 1.0 0.961,1.05 2408 24092 0.369 1.04 0.958,1.12 687 6916
367.1 Myopia sense organs Both 0.6887 1.01 0.955,1.07 1251 12519 0.5236 1.02 0.961,1.08 1196 11982
367.2 Astigmatism sense organs Both 0.2089 0.912 0.789,1.05 190 1899 0.4276 0.942 0.811,1.09 178 1823
367.8 Hypermetropia sense organs Both 0.5929 1.04 0.91,1.18 253 2530 0.9594 1.0 0.876,1.15 239 2428
367.9 Blindness and low vision sense organs Both 0.5636 1.02 0.947,1.11 719 7198 0.369 1.04 0.958,1.12 687 6916
368 Visual disturbances sense organs Both 0.3936 1.02 0.979,1.06 2962 29648 0.9484 1.0 0.921,1.09 583 5919
368.1 Amblyopia sense organs Both 0.2404 1.05 0.965,1.15 532 5322 0.2523 1.06 0.963,1.16 505 5072
368.2 Diplopia and disorders of binocular vision sense organs Both 0.9333 0.997 0.924,1.08 727 7288 0.8974 0.995 0.92,1.08 693 7043
368.3 Anisometropia sense organs Both 0.354 1.08 0.917,1.28 154 1548 0.5957 1.05 0.884,1.24 145 1471
368.4 Visual field defects sense organs Both 0.04898 1.12 1.0,1.25 333 3327 0.1355 1.09 0.973,1.23 310 3204
368.9 Subjective visual disturbances sense organs Both 0.9484 1.0 0.923,1.09 612 6115 0.9484 1.0 0.921,1.09 583 5919
369 Infection of the eye sense organs Both 0.5902 0.976 0.894,1.07 553 5544 0.6339 0.965 0.834,1.12 202 2054
369.2 Eye infection, viral sense organs Both 0.5943 1.05 0.875,1.26 125 1257 0.778 1.03 0.853,1.24 120 1212
369.5 Conjunctivitis, infectious sense organs Both 0.5715 0.96 0.832,1.11 213 2128 0.6339 0.965 0.834,1.12 202 2054
370 Keratitis sense organs Both 0.2729 0.934 0.828,1.05 286 2855 0.3342 0.919 0.775,1.09 137 1355
370.1 Corneal ulcer sense organs Both 0.2938 0.914 0.772,1.08 141 1408 0.3342 0.919 0.775,1.09 137 1355
371 Inflammation of the eye sense organs Both 0.5585 1.01 0.974,1.05 3045 30480 0.4966 1.02 0.972,1.06 2219 22759
371.1 Uveitis, noninfectious or NOS sense organs Both 0.7816 0.987 0.9,1.08 482 4821 0.7852 1.01 0.921,1.11 455 4667
371.3 Inflammation of eyelids sense organs Both 0.342 1.02 0.978,1.07 2353 23555 0.4966 1.02 0.972,1.06 2219 22759
372 Disorders of conjunctiva sense organs Both 0.7047 0.986 0.914,1.06 760 7602 0.9795 0.999 0.924,1.08 709 7273
374 Other disorders of eyelids sense organs Both 0.2844 1.02 0.988,1.04 5680 56807 0.1514 0.965 0.918,1.01 1735 17480
374.1 Ectropion or entropion sense organs Both 0.2831 1.04 0.972,1.1 1063 10645 0.2472 1.04 0.973,1.11 969 10113
374.3 Ptosis of eyelid sense organs Both 0.1622 0.966 0.921,1.01 1825 18232 0.1514 0.965 0.918,1.01 1735 17480
375 Disorders of lacrimal system sense organs Both 0.00309 1.07 1.02,1.12 2204 22031 0.01585 1.09 1.02,1.17 830 8580
375.2 Epiphora sense organs Both 0.01413 1.09 1.02,1.17 898 8969 0.01585 1.09 1.02,1.17 830 8580
376 Disorders of the orbit sense organs Both 0.881 1.02 0.813,1.27 86 859 0.9705 0.996 0.791,1.25 80 827
377 Disorders of optic nerve and visual pathways sense organs Both 0.0871 1.1 0.986,1.23 361 3618 0.3221 1.1 0.907,1.35 121 1223
377.1 Optic atrophy sense organs Both 0.8492 0.974 0.743,1.28 56 570 0.6577 1.07 0.804,1.41 52 552
377.3 Optic neuritis/neuropathy sense organs Both 0.2576 1.12 0.921,1.36 125 1249 0.3221 1.1 0.907,1.35 121 1223
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.3491 1.03 0.972,1.08 1410 14116 0.3908 0.946 0.833,1.07 264 2653
378.1 Strabismus (not specified as paralytic) sense organs Both 0.4732 1.03 0.958,1.1 909 9082 0.3388 1.03 0.965,1.11 886 8771
378.2 Nystagmus and other irregular eye movements sense organs Both 0.1483 1.11 0.964,1.27 213 2138 0.3483 1.07 0.927,1.24 199 2049
378.5 Paralytic strabismus sense organs Both 0.3311 0.94 0.83,1.06 275 2755 0.3908 0.946 0.833,1.07 264 2653
379 Other disorders of eye sense organs Both 0.7998 0.996 0.962,1.03 3703 37063 0.9099 1.01 0.857,1.19 159 1625
379.2 Disorders of vitreous body sense organs Both 0.2123 0.965 0.912,1.02 1367 13665 0.5508 0.983 0.928,1.04 1320 13065
379.3 Aphakia and other disorders of lens sense organs Both 0.118 1.04 0.99,1.09 1813 18134 0.0631 1.05 0.998,1.1 1723 17246
379.4 Anomalies of pupillary function sense organs Both 0.0955 0.816 0.642,1.04 71 710 0.1982 0.852 0.667,1.09 69 684
379.5 Disorders of iris and ciliary body sense organs Both 0.6823 0.979 0.886,1.08 400 4028 0.912 1.01 0.907,1.12 377 3854
379.9 Pain, swelling or discharge of eye sense organs Both 0.6138 1.04 0.889,1.22 169 1690 0.9099 1.01 0.857,1.19 159 1625
380 Disorders of external ear sense organs Both 0.04571 1.09 1.0,1.18 642 6413 0.2979 0.943 0.845,1.05 344 3481
380.1 Otitis externa sense organs Both 0.4875 1.03 0.943,1.13 509 5107 0.5754 1.03 0.936,1.13 485 4934
380.4 Impacted cerumen sense organs Both 0.3365 0.949 0.852,1.06 362 3614 0.2979 0.943 0.845,1.05 344 3481
381 Otitis media and Eustachian tube disorders sense organs Both 0.7295 1.01 0.964,1.05 2150 21493 0.5636 1.04 0.918,1.17 273 2699
381.1 Otitis media sense organs Both 0.4256 1.02 0.971,1.07 1767 17668 0.2661 1.04 0.97,1.12 820 8228
381.11 Suppurative and unspecified otitis media sense organs Both 0.1786 1.05 0.978,1.13 852 8524 0.2661 1.04 0.97,1.12 820 8228
381.2 Eustachian tube disorders sense organs Both 0.2723 0.919 0.791,1.07 193 1929 0.2786 0.919 0.789,1.07 189 1867
381.3 Mastoiditis & related conditions sense organs Both 0.09333 0.872 0.744,1.02 171 1709 0.06457 0.86 0.732,1.01 168 1645
381.9 Otorrhea sense organs Both 0.537 1.04 0.921,1.17 281 2807 0.5636 1.04 0.918,1.17 273 2699
382 Otalgia sense organs Both 0.8128 1.01 0.903,1.14 308 3084 0.7816 1.02 0.904,1.14 298 2975
383 Otosclerosis sense organs Both 0.1531 1.09 0.969,1.23 309 3090 0.207 1.08 0.958,1.22 298 2987
384 Other disorders of tympanic membrane sense organs Both 0.4613 0.979 0.925,1.04 1299 12991 0.6223 0.984 0.923,1.05 1008 10083
384.4 Perforation of tympanic membrane sense organs Both 0.778 0.991 0.93,1.06 1043 10432 0.6223 0.984 0.923,1.05 1008 10083
385 Other disorders of middle ear and mastoid sense organs Both 0.3837 1.03 0.96,1.11 783 7837 0.8091 1.02 0.89,1.16 233 2316
385.3 Cholesteatoma sense organs Both 0.1122 1.07 0.984,1.16 607 6078 0.0912 1.08 0.988,1.17 594 5849
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.695 1.03 0.9,1.17 241 2409 0.8091 1.02 0.89,1.16 233 2316
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.08318 1.04 0.994,1.1 1736 17373 0.01202 1.04 1.01,1.07 4379 44026
386.1 Meniere's disease sense organs Both 0.151 1.06 0.978,1.16 576 5768 0.1648 1.06 0.975,1.16 552 5542
386.2 Peripheral or central vertigo sense organs Both 0.5333 1.03 0.931,1.15 377 3763 0.6808 1.02 0.918,1.14 360 3616
386.3 Labyrinthitis sense organs Both 0.3258 1.04 0.964,1.12 765 7664 0.2529 1.04 0.97,1.13 734 7384
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.01288 1.04 1.01,1.07 4582 45806 0.01202 1.04 1.01,1.07 4379 44026
388 Other disorders of ear sense organs Both 0.5309 1.05 0.907,1.21 202 2017 0.4178 1.06 0.918,1.23 197 1940
389 Hearing loss sense organs Both 0.01549 1.04 1.01,1.07 4188 41944 0.8531 1.01 0.92,1.11 491 4915
389.1 Sensorineural hearing loss sense organs Both 0.6442 0.978 0.888,1.08 456 4553 0.6918 0.98 0.889,1.08 437 4365
389.2 Conductive hearing loss sense organs Both 0.03162 1.11 1.01,1.22 450 4497 0.02884 1.12 1.01,1.23 433 4344
389.4 Tinnitus sense organs Both 0.8035 1.01 0.924,1.11 513 5134 0.8531 1.01 0.92,1.11 491 4915
394 Rheumatic disease of the heart valves circulatory system Both 0.3855 1.01 0.984,1.04 4899 48974 0.2168 1.04 0.976,1.11 1003 10088
394.2 Mitral valve disease circulatory system Both 0.9683 0.999 0.962,1.04 2993 29922 0.7834 0.995 0.957,1.03 2844 28599
394.3 Aortic valve disease circulatory system Both 0.1679 1.04 0.983,1.1 1282 12814 0.3873 1.03 0.967,1.09 1193 12237
394.7 Disease of tricuspid valve circulatory system Both 0.0871 1.06 0.992,1.13 1058 10566 0.2168 1.04 0.976,1.11 1003 10088
395 Heart valve disorders circulatory system Both 0.5023 1.01 0.979,1.04 4223 42219 0.1219 1.04 0.988,1.1 1383 14271
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.8035 0.995 0.958,1.03 2891 28900 0.6266 0.99 0.952,1.03 2744 27611
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.1009 0.901 0.795,1.02 276 2766 0.04266 0.876 0.772,0.995 263 2619
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.2123 1.13 0.935,1.35 105 1039 0.3404 1.1 0.907,1.33 101 1001
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.8185 1.03 0.827,1.27 97 970 0.9162 0.988 0.791,1.23 89 932
395.6 Heart valve replaced circulatory system Both 0.02455 1.06 1.01,1.12 1495 14942 0.1219 1.04 0.988,1.1 1383 14271
396 Abnormal heart sounds circulatory system Both 0.6966 0.987 0.927,1.05 1048 10468 0.7656 0.99 0.928,1.06 997 10073
401 Hypertension circulatory system Both 3.388E-6 1.02 1.01,1.03 73956 266957 0.9268 1.01 0.835,1.22 123 1384
401.1 Essential hypertension circulatory system Both 3.548E-6 1.02 1.01,1.03 73731 266739 2.512E-4 1.02 1.01,1.03 69621 259061
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.002692 1.08 1.03,1.13 1898 19031 0.01259 1.07 1.02,1.13 1397 14831
401.21 Hypertensive heart disease circulatory system Both 0.695 1.02 0.918,1.14 370 3699 0.7586 1.02 0.913,1.13 360 3548
401.22 Hypertensive chronic kidney disease circulatory system Both 0.002399 1.08 1.03,1.14 1543 15483 0.01259 1.07 1.02,1.13 1397 14831
401.3 Other hypertensive complications circulatory system Both 0.4246 1.07 0.901,1.28 144 1438 0.9268 1.01 0.835,1.22 123 1384
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.879 0.996 0.944,1.05 1479 14786 0.7907 0.993 0.939,1.05 1397 14293
411 Ischemic Heart Disease circulatory system Both 0.01995 1.01 1.0,1.03 31245 210714 0.6668 0.987 0.929,1.05 1162 11645
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.04266 1.03 1.0,1.06 5152 51498 0.05495 1.03 0.999,1.06 4873 49085
411.2 Myocardial infarction circulatory system Both 0.07586 1.02 0.998,1.04 11950 112699 0.03162 1.02 1.0,1.04 11419 107742
411.3 Angina pectoris circulatory system Both 4.266E-6 1.04 1.02,1.06 15888 143745 7.413E-7 1.04 1.03,1.06 15093 137453
411.4 Coronary atherosclerosis circulatory system Both 0.04467 1.02 1.0,1.03 20171 154621 0.7464 0.987 0.911,1.07 668 6672
411.41 Aneurysm and dissection of heart circulatory system Both 0.9354 0.997 0.922,1.08 700 6997 0.7464 0.987 0.911,1.07 668 6672
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.01096 1.02 1.01,1.04 15290 131798 0.01318 1.02 1.0,1.04 14389 125969
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.4406 0.977 0.921,1.04 1218 12166 0.6668 0.987 0.929,1.05 1162 11645
414 Other forms of chronic heart disease circulatory system Both 0.778 0.993 0.946,1.04 1823 18228 0.865 1.02 0.795,1.31 69 687
414.2 ASCVD circulatory system Both 0.9036 1.02 0.793,1.3 72 719 0.865 1.02 0.795,1.31 69 687
415 Pulmonary heart disease circulatory system Both 0.1245 0.976 0.947,1.01 4476 44810 0.7178 1.02 0.922,1.12 425 4267
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.7745 1.04 0.817,1.31 75 750 0.8492 0.976 0.763,1.25 68 718
415.2 Chronic pulmonary heart disease circulatory system Both 0.6776 1.02 0.935,1.11 601 6002 0.7178 1.02 0.922,1.12 425 4267
415.21 Primary pulmonary hypertension circulatory system Both 0.6546 1.02 0.928,1.13 448 4475 0.7178 1.02 0.922,1.12 425 4267
416 Cardiomegaly circulatory system Both 0.3133 1.02 0.981,1.06 2680 26793 0.3758 1.02 0.978,1.06 2552 25564
418 Nonspecific chest pain circulatory system Both 0.07244 1.01 0.999,1.02 28599 270106 0.2042 1.02 0.988,1.06 3429 34246
418.1 Precordial pain circulatory system Both 0.1524 1.03 0.991,1.06 3551 35541 0.2042 1.02 0.988,1.06 3429 34246
420 Carditis circulatory system Both 0.05623 1.04 0.999,1.09 2106 21053 0.03548 1.09 1.01,1.18 689 6872
420.1 Myocarditis circulatory system Both 0.673 0.961 0.798,1.16 127 1267 0.8995 0.988 0.815,1.2 117 1202
420.2 Pericarditis circulatory system Both 0.2679 1.03 0.976,1.09 1338 13371 0.1306 1.17 0.955,1.43 108 1079
420.21 Acute pericarditis circulatory system Both 0.8375 0.985 0.856,1.13 223 2227 0.6622 0.969 0.84,1.12 216 2137
420.22 Chronic pericarditis circulatory system Both 0.1191 1.17 0.961,1.41 113 1129 0.1306 1.17 0.955,1.43 108 1079
420.3 Endocarditis circulatory system Both 0.02884 1.09 1.01,1.18 719 7194 0.03548 1.09 1.01,1.18 689 6872
425 Cardiomyopathy circulatory system Both 0.5321 0.982 0.927,1.04 1271 12699 0.2951 0.865 0.658,1.14 59 583
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.6457 0.986 0.93,1.05 1236 12349 0.05248 0.849 0.719,1.0 159 1562
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.6546 1.04 0.874,1.24 133 1329 0.6053 1.05 0.879,1.25 131 1276
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.04571 0.847 0.719,0.997 163 1629 0.05248 0.849 0.719,1.0 159 1562
425.8 Other cardiomyopathy circulatory system Both 0.3126 0.87 0.663,1.14 60 600 0.2951 0.865 0.658,1.14 59 583
426 Cardiac conduction disorders circulatory system Both 0.07413 1.02 0.998,1.05 6910 69146 0.02818 1.05 1.01,1.1 2123 21653
426.2 Atrioventricular [AV] block circulatory system Both 0.2858 1.02 0.98,1.07 2114 21162 0.8035 0.977 0.816,1.17 126 1263
426.21 First degree AV block circulatory system Both 0.6053 1.02 0.953,1.09 986 9867 0.7621 1.01 0.945,1.08 932 9399
426.23 Second degree AV block circulatory system Both 0.3954 1.04 0.948,1.15 452 4515 0.6095 1.03 0.93,1.13 425 4323
426.24 Atrioventricular block, complete circulatory system Both 0.5346 1.03 0.944,1.12 587 5868 0.6295 1.02 0.936,1.12 558 5599
426.25 Other heart block circulatory system Both 0.5754 0.951 0.798,1.13 131 1318 0.8035 0.977 0.816,1.17 126 1263
426.3 Bundle branch block circulatory system Both 0.3963 1.02 0.98,1.05 3336 33359 0.6397 1.01 0.962,1.06 1671 16671
426.31 Right bundle branch block circulatory system Both 0.1637 1.04 0.985,1.1 1494 14933 0.1455 1.04 0.986,1.1 1413 14293
426.32 Left bundle branch block circulatory system Both 0.5821 1.01 0.965,1.07 1750 17503 0.6397 1.01 0.962,1.06 1671 16671
426.4 Anomalous atrioventricular excitation circulatory system Both 0.8472 0.987 0.861,1.13 233 2328 0.6918 0.972 0.847,1.12 227 2250
426.8 Other cardiac conduction disorders circulatory system Both 0.8375 1.03 0.779,1.36 60 600 0.8892 0.979 0.731,1.31 54 568
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.01549 1.05 1.01,1.1 2475 24774 0.02818 1.05 1.01,1.1 2123 21653
426.91 Cardiac pacemaker in situ circulatory system Both 0.02239 1.05 1.01,1.1 2274 22762 0.02818 1.05 1.01,1.1 2123 21653
427 Cardiac dysrhythmias circulatory system Both 0.2118 1.01 0.995,1.02 24207 206016 0.07586 1.03 0.997,1.07 3652 36763
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.9441 1.0 0.965,1.04 3199 32017 0.3148 1.04 0.967,1.11 890 8918
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.7907 1.01 0.964,1.05 2344 23474 0.9954 1.0 0.957,1.04 2220 22570
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.4539 1.03 0.959,1.1 936 9365 0.3148 1.04 0.967,1.11 890 8918
427.2 Atrial fibrillation and flutter circulatory system Both 0.4786 1.01 0.989,1.02 14628 133501 0.7907 1.0 0.985,1.02 13783 127510
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.5689 1.01 0.975,1.05 3228 32281 0.9016 1.0 0.966,1.04 3047 30885
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.5585 1.02 0.959,1.08 1193 11915 0.6138 1.02 0.952,1.09 955 9443
427.41 Ventricular fibrillation and flutter circulatory system Both 0.9908 0.999 0.895,1.12 344 3437 0.8337 1.01 0.904,1.13 328 3276
427.42 Cardiac arrest circulatory system Both 0.787 1.01 0.945,1.08 990 9890 0.6138 1.02 0.952,1.09 955 9443
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.4266 1.03 0.961,1.1 952 9541 0.5998 1.02 0.95,1.09 887 9131
427.6 Premature beats circulatory system Both 0.0912 1.08 0.987,1.18 535 5358 0.9333 1.01 0.832,1.22 112 1125
427.61 Supraventricular premature beats circulatory system Both 0.7603 1.03 0.852,1.24 117 1168 0.9333 1.01 0.832,1.22 112 1125
427.7 Tachycardia NOS circulatory system Both 0.9484 0.999 0.956,1.04 2185 21865 0.811 1.01 0.961,1.05 2082 21031
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.8531 1.01 0.914,1.12 402 4029 0.5998 0.973 0.878,1.08 379 3828
427.9 Palpitations circulatory system Both 0.0537 1.03 0.999,1.07 3811 38105 0.07586 1.03 0.997,1.07 3652 36763
428 Congestive heart failure; nonhypertensive circulatory system Both 0.5284 1.01 0.981,1.04 5605 56018 0.8995 0.998 0.967,1.03 4217 42379
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.6561 1.01 0.966,1.06 2111 21108 0.415 1.02 0.973,1.07 2009 20064
428.2 Heart failure NOS circulatory system Both 0.6839 1.01 0.976,1.04 4455 44524 0.8995 0.998 0.967,1.03 4217 42379
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.8185 0.991 0.917,1.07 716 7168 0.6368 0.964 0.828,1.12 187 1905
429.1 Heart transplant/surgery circulatory system Both 0.0631 0.786 0.609,1.01 64 639 0.0955 0.792 0.602,1.04 53 607
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.975 0.999 0.912,1.09 522 5211 0.9572 0.997 0.91,1.09 508 5010
429.3 Symptoms involving cardiovascular system circulatory system Both 0.6561 0.967 0.833,1.12 196 1978 0.6368 0.964 0.828,1.12 187 1905
430 Intracranial hemorrhage circulatory system Both 0.8166 0.994 0.948,1.04 1883 18825 0.09333 0.893 0.782,1.02 256 2543
430.1 Subarachnoid hemorrhage circulatory system Both 0.869 1.01 0.937,1.08 836 8353 0.8531 1.01 0.936,1.08 807 8088
430.2 Intracerebral hemorrhage circulatory system Both 0.8995 1.0 0.933,1.08 765 7656 0.743 0.987 0.915,1.07 717 7317
430.3 Subdural hemorrhage circulatory system Both 0.1138 0.901 0.791,1.03 267 2667 0.09333 0.893 0.782,1.02 256 2543
433 Cerebrovascular disease circulatory system Both 0.01202 1.03 1.01,1.05 8749 87456 0.5875 0.984 0.928,1.04 1215 12206
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.01122 1.08 1.02,1.15 1185 11825 0.2958 1.08 0.935,1.25 213 2158
433.12 Cerebral atherosclerosis circulatory system Both 0.3214 1.07 0.934,1.23 227 2267 0.2958 1.08 0.935,1.25 213 2158
433.2 Occlusion of cerebral arteries circulatory system Both 0.1429 1.02 0.992,1.06 4233 42320 0.811 0.994 0.944,1.05 1592 16031
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.7396 0.992 0.943,1.04 1680 16794 0.811 0.994 0.944,1.05 1592 16031
433.3 Cerebral ischemia circulatory system Both 0.05888 1.04 0.999,1.08 2895 28989 0.4898 1.02 0.971,1.06 2024 20377
433.31 Transient cerebral ischemia circulatory system Both 0.3622 1.02 0.976,1.07 2135 21379 0.4898 1.02 0.971,1.06 2024 20377
433.5 Cerebral aneurysm circulatory system Both 0.6383 1.03 0.922,1.14 394 3939 0.7112 1.02 0.917,1.14 382 3800
433.8 Late effects of cerebrovascular disease circulatory system Both 0.7638 0.991 0.936,1.05 1279 12783 0.5875 0.984 0.928,1.04 1215 12206
440 Atherosclerosis circulatory system Both 0.2455 1.03 0.977,1.09 1380 13822 0.7129 0.976 0.86,1.11 268 2724
440.1 Atherosclerosis of renal artery circulatory system Both 0.2099 1.14 0.931,1.39 113 1129 0.3304 1.11 0.899,1.37 99 1066
440.2 Atherosclerosis of the extremities circulatory system Both 0.08511 1.07 0.991,1.15 805 8070 0.1247 1.06 0.984,1.15 760 7662
440.9 Atherosclerosis of aorta circulatory system Both 0.9795 0.998 0.883,1.13 287 2867 0.7129 0.976 0.86,1.11 268 2724
441 Vascular insufficiency of intestine circulatory system Both 0.08511 1.07 0.99,1.17 614 6154 0.4898 0.957 0.844,1.08 266 2701
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.7852 0.983 0.87,1.11 283 2827 0.4898 0.957 0.844,1.08 266 2701
442 Other aneurysm circulatory system Both 0.6026 1.01 0.966,1.06 1892 18959 0.3206 0.929 0.803,1.07 193 1953
442.1 Aortic aneurysm circulatory system Both 0.7228 1.01 0.956,1.07 1458 14625 0.7499 1.01 0.943,1.09 874 8792
442.11 Abdominal aortic aneurysm circulatory system Both 0.6295 1.02 0.95,1.09 931 9341 0.7499 1.01 0.943,1.09 874 8792
442.2 Aneurysm of iliac artery circulatory system Both 0.2818 1.12 0.913,1.37 102 1019 0.1262 1.18 0.955,1.45 93 968
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.05888 1.16 0.995,1.36 169 1696 0.05754 1.17 0.995,1.37 162 1620
442.4 Arterial dissection circulatory system Both 0.9931 0.999 0.757,1.32 54 549 0.8035 0.965 0.727,1.28 52 536
442.8 Aneurysm of other specified artery circulatory system Both 0.3698 0.937 0.812,1.08 203 2028 0.3206 0.929 0.803,1.07 193 1953
443 Peripheral vascular disease circulatory system Both 0.02042 1.04 1.01,1.07 3921 39273 0.2938 1.02 0.981,1.07 2464 24573
443.1 Raynaud's syndrome circulatory system Both 0.006457 1.09 1.02,1.16 1145 11438 0.02188 1.08 1.01,1.14 1083 11045
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.5309 1.03 0.93,1.15 384 3878 0.7311 1.02 0.914,1.14 366 3712
443.8 Other specified peripheral vascular diseases circulatory system Both 0.02818 1.04 1.0,1.07 3686 36906 0.04786 1.04 1.0,1.07 3510 35273
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.3199 1.02 0.98,1.06 2579 25846 0.2938 1.02 0.981,1.07 2464 24573
444 Arterial embolism and thrombosis circulatory system Both 0.2443 1.04 0.973,1.11 922 9251 0.1112 1.08 0.983,1.18 525 5285
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.1343 1.07 0.979,1.17 554 5552 0.1112 1.08 0.983,1.18 525 5285
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.8395 0.993 0.925,1.07 822 8226 0.9162 0.993 0.869,1.13 227 2299
446.4 Wegener's granulomatosis circulatory system Both 0.7047 0.972 0.84,1.12 188 1878 0.7907 0.979 0.839,1.14 168 1817
446.5 Giant cell arteritis circulatory system Both 0.9863 0.999 0.903,1.11 388 3879 0.9616 0.997 0.898,1.11 367 3700
446.9 Arteritis NOS circulatory system Both 0.9683 1.0 0.88,1.14 239 2400 0.9162 0.993 0.869,1.13 227 2299
447 Other disorders of arteries and arterioles circulatory system Both 0.869 1.0 0.95,1.06 1327 13316 0.3936 1.03 0.961,1.11 826 8302
447.1 Stricture of artery circulatory system Both 0.3112 1.04 0.967,1.11 868 8712 0.3936 1.03 0.961,1.11 826 8302
448 Disease of capillaries circulatory system Both 0.2805 1.1 0.925,1.31 142 1420 0.2958 1.1 0.92,1.31 132 1366
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.7925 1.01 0.935,1.09 704 7034 0.9141 0.996 0.918,1.08 649 6770
451 Phlebitis and thrombophlebitis circulatory system Both 0.15 0.976 0.945,1.01 3955 39683 0.07762 0.969 0.936,1.0 3487 35516
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.1079 0.973 0.94,1.01 3683 36977 0.07762 0.969 0.936,1.0 3487 35516
452 Other venous embolism and thrombosis circulatory system Both 0.4169 1.04 0.95,1.13 564 5645 0.526 1.03 0.941,1.13 532 5415
454 Varicose veins circulatory system Both 0.3855 0.991 0.972,1.01 11180 112047 0.3097 0.955 0.875,1.04 569 6060
454.1 Varicose veins of lower extremity circulatory system Both 0.2754 0.989 0.971,1.01 11503 115272 0.3097 0.955 0.875,1.04 569 6060
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.3908 0.964 0.887,1.05 624 6325 0.3097 0.955 0.875,1.04 569 6060
455 Hemorrhoids circulatory system Both 0.4227 0.995 0.981,1.01 23452 234585 0.2891 0.993 0.979,1.01 22449 226271
456 Chronic venous insufficiency [CVI] circulatory system Both 0.413 0.939 0.807,1.09 184 1868 0.1832 0.899 0.768,1.05 169 1785
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.1288 0.852 0.693,1.05 97 967 0.1268 0.85 0.69,1.05 95 920
458 Hypotension circulatory system Both 0.4645 1.01 0.983,1.04 5769 57772 0.8831 0.997 0.962,1.03 3319 33577
458.1 Orthostatic hypotension circulatory system Both 0.3707 1.03 0.97,1.09 1335 13376 0.2438 1.03 0.977,1.1 1276 12738
458.2 Iatrogenic hypotension circulatory system Both 0.004169 1.21 1.06,1.39 235 2348 0.01862 1.18 1.03,1.35 220 2218
458.9 Hypotension NOS circulatory system Both 0.7745 0.995 0.961,1.03 3494 35005 0.8831 0.997 0.962,1.03 3319 33577
459 Other disorders of circulatory system circulatory system Both 0.1466 1.01 0.996,1.03 16268 160790 0.2911 1.01 0.992,1.03 15202 152830
459.1 Hemorrhage NOS circulatory system Both 0.4529 0.938 0.792,1.11 142 1420 0.4853 0.94 0.791,1.12 132 1358
459.9 Circulatory disease NEC circulatory system Both 0.09333 1.01 0.998,1.03 16103 159422 0.2911 1.01 0.992,1.03 15202 152830
464 Acute sinusitis respiratory Both 0.3899 0.939 0.813,1.08 196 1957 0.3365 0.93 0.803,1.08 189 1890
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.859 0.996 0.954,1.04 2283 22827 0.3707 1.08 0.916,1.27 158 1584
465.2 Acute pharyngitis respiratory Both 0.9247 0.997 0.929,1.07 835 8348 0.8974 0.995 0.926,1.07 795 8069
465.4 Acute laryngitis and tracheitis respiratory Both 0.4178 1.07 0.912,1.25 165 1649 0.3707 1.08 0.916,1.27 158 1584
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.8892 1.0 0.972,1.03 4654 46553 0.7261 1.01 0.975,1.04 4504 45103
471 Nasal polyps respiratory Both 0.9817 1.0 0.965,1.04 3297 32973 0.8017 1.0 0.969,1.04 3159 31723
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.04677 1.07 1.0,1.14 960 9594 0.0537 1.07 0.999,1.14 923 9268
473 Diseases of the larynx and vocal cords respiratory Both 0.0166 1.05 1.01,1.09 2554 25548 0.001549 1.11 1.04,1.18 1034 10320
473.1 Chronic laryngitis respiratory Both 0.6383 0.953 0.778,1.17 104 1038 0.5433 0.937 0.761,1.15 99 993
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.4083 1.05 0.93,1.2 264 2647 0.2529 1.08 0.948,1.23 253 2525
473.4 Voice disturbance respiratory Both 9.55E-4 1.11 1.04,1.19 1080 10789 0.001549 1.11 1.04,1.18 1034 10320
474 Acute and chronic tonsillitis respiratory Both 0.3945 0.979 0.933,1.03 1772 17710 0.3936 0.973 0.915,1.04 1090 10935
474.1 Acute tonsillitis respiratory Both 0.2213 0.947 0.867,1.03 549 5486 0.4217 0.964 0.882,1.05 532 5373
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.4295 0.976 0.918,1.04 1122 11199 0.3936 0.973 0.915,1.04 1090 10935
475 Chronic sinusitis respiratory Both 0.6839 1.01 0.969,1.05 2589 25882 0.7345 1.01 0.967,1.05 2493 25021
476 Allergic rhinitis respiratory Both 0.8035 1.01 0.946,1.07 1055 10563 0.9863 0.999 0.937,1.07 1003 10254
477 Epistaxis or throat hemorrhage respiratory Both 0.6792 0.991 0.951,1.03 2447 24452 0.6166 0.989 0.948,1.03 2334 23396
478 Throat pain respiratory Both 0.04898 1.11 1.0,1.24 377 3789 0.03631 1.12 1.01,1.25 362 3663
479 Other upper respiratory disease respiratory Both 0.00138 1.05 1.02,1.09 4074 40737 0.003981 1.05 1.02,1.08 3900 39330
480 Pneumonia respiratory Both 0.8492 0.998 0.978,1.02 10336 103397 0.1148 0.942 0.874,1.01 750 7582
480.1 Bacterial pneumonia respiratory Both 0.9226 0.999 0.974,1.02 6637 66410 0.6546 0.951 0.762,1.19 88 893
480.11 Pneumococcal pneumonia respiratory Both 0.787 1.0 0.977,1.03 5883 58863 0.5888 1.01 0.98,1.04 5597 56341
480.12 Pseudomonal pneumonia respiratory Both 0.9397 0.992 0.802,1.23 93 929 0.6546 0.951 0.762,1.19 88 893
480.2 Viral pneumonia respiratory Both 0.1138 1.22 0.954,1.55 72 720 0.1084 1.23 0.955,1.58 66 701
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.04074 1.24 1.01,1.52 99 989 0.04365 1.24 1.01,1.54 92 947
480.5 Bronchopneumonia and lung abscess respiratory Both 0.157 0.949 0.883,1.02 794 7951 0.1148 0.942 0.874,1.01 750 7582
481 Influenza respiratory Both 0.3304 0.945 0.843,1.06 328 3278 0.4395 0.955 0.849,1.07 310 3173
483 Acute bronchitis and bronchiolitis respiratory Both 0.1517 1.12 0.96,1.3 193 1930 0.1535 1.12 0.959,1.3 186 1857
495 Asthma respiratory Both 0.9705 1.0 0.987,1.01 25689 250406 0.5236 0.958 0.838,1.09 236 2431
495.2 Asthma with exacerbation respiratory Both 0.507 0.957 0.841,1.09 250 2510 0.5236 0.958 0.838,1.09 236 2431
496 Chronic airway obstruction respiratory Both 0.354 1.01 0.989,1.03 10424 101546 0.133 1.04 0.989,1.09 1763 18002
496.1 Emphysema respiratory Both 0.228 0.97 0.923,1.02 1743 17438 0.1107 0.959 0.912,1.01 1662 16623
496.2 Chronic bronchitis respiratory Both 0.8128 1.0 0.967,1.04 2947 29498 0.3908 1.02 0.978,1.06 2600 25831
496.21 Obstructive chronic bronchitis respiratory Both 0.5794 1.01 0.972,1.05 2706 27081 0.3908 1.02 0.978,1.06 2600 25831
496.3 Bronchiectasis respiratory Both 0.1247 1.04 0.99,1.09 1885 18859 0.133 1.04 0.989,1.09 1763 18002
497 Bronchitis respiratory Both 0.879 1.01 0.927,1.09 626 6267 0.8933 1.01 0.925,1.09 596 6022
500 Lung disease due to external agents respiratory Both 0.00955 1.15 1.03,1.27 412 4099 0.07762 1.13 0.986,1.3 223 2259
500.1 Extrinsic allergic alveolitis respiratory Both 0.8453 1.02 0.818,1.28 79 784 0.6668 0.95 0.752,1.2 74 749
500.2 Pneumoconiosis respiratory Both 0.02884 1.16 1.02,1.32 243 2409 0.07762 1.13 0.986,1.3 223 2259
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.3228 1.04 0.961,1.13 656 6557 0.2118 1.05 0.97,1.15 625 6236
502 Postinflammatory pulmonary fibrosis respiratory Both 0.6383 0.984 0.919,1.05 917 9193 0.4519 0.974 0.908,1.04 868 8742
503 Pulmonary congestion and hypostasis respiratory Both 0.4853 1.03 0.943,1.13 508 5079 0.2094 1.06 0.967,1.17 484 4867
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.2858 0.94 0.84,1.05 328 3280 0.2606 0.936 0.834,1.05 313 3131
505 Other pulmonary inflamation or edema respiratory Both 0.2477 0.862 0.67,1.11 61 610 0.139 0.823 0.636,1.07 58 581
506 Empyema and pneumothorax respiratory Both 0.6902 1.01 0.952,1.08 1133 11362 0.6295 1.02 0.954,1.08 1085 10893
507 Pleurisy; pleural effusion respiratory Both 0.912 0.999 0.973,1.02 6419 64252 0.9572 1.0 0.975,1.03 6085 61409
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.6152 0.988 0.944,1.03 1996 19947 0.7998 0.994 0.948,1.04 1904 19117
509 Respiratory failure, insufficiency, arrest respiratory Both 0.6353 1.01 0.97,1.05 2599 26031 0.8185 1.01 0.909,1.13 370 3672
509.1 Respiratory failure respiratory Both 0.6152 1.01 0.967,1.06 2068 20708 0.3597 1.02 0.976,1.07 1976 19714
509.2 Respiratory insufficiency respiratory Both 0.514 1.02 0.968,1.07 1806 18106 0.2754 1.03 0.978,1.08 1732 17239
509.5 Respiratory arrest respiratory Both 0.8531 1.02 0.861,1.2 143 1429 0.9772 0.997 0.843,1.18 138 1376
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.8204 1.01 0.911,1.12 386 3863 0.8185 1.01 0.909,1.13 370 3672
510 Other diseases of lung respiratory Both 0.01514 1.1 1.02,1.18 755 7554 0.03162 1.09 1.01,1.18 718 7230
512 Other symptoms of respiratory system respiratory Both 0.02089 1.03 1.0,1.05 9031 90349 0.8954 1.0 0.936,1.08 874 8767
512.1 Wheezing respiratory Both 0.6081 1.04 0.905,1.19 220 2196 0.6223 1.04 0.902,1.19 208 2100
512.2 Painful respiration respiratory Both 0.7586 1.02 0.888,1.18 207 2075 0.7464 1.02 0.887,1.18 200 1995
512.7 Shortness of breath respiratory Both 0.0537 1.03 1.0,1.06 5842 58498 0.05495 1.03 0.999,1.06 5593 56163
512.8 Cough respiratory Both 0.1991 1.03 0.987,1.07 2866 28642 0.2518 1.02 0.984,1.06 2716 27537
512.9 Other dyspnea respiratory Both 0.6855 1.01 0.947,1.09 914 9124 0.8954 1.0 0.936,1.08 874 8767
513 Respiratory abnormalities respiratory Both 0.08913 1.08 0.989,1.17 611 6112 0.4375 1.07 0.902,1.27 146 1458
513.3 Hypoventilation respiratory Both 0.3581 1.12 0.883,1.41 83 830 0.369 1.12 0.878,1.42 78 793
513.4 Hyperventilation respiratory Both 0.526 0.96 0.847,1.09 278 2778 0.5781 0.965 0.849,1.1 269 2673
513.8 Disorders of diaphragm respiratory Both 0.6012 1.05 0.884,1.24 153 1538 0.4375 1.07 0.902,1.27 146 1458
514 Abnormal findings examination of lungs respiratory Both 0.5702 1.01 0.971,1.06 2465 24673 0.6053 1.01 0.969,1.06 2338 23613
516 Abnormal sputum respiratory Both 0.9268 1.0 0.958,1.05 2132 21335 0.955 1.0 0.956,1.05 1963 19889
516.1 Hemoptysis respiratory Both 0.7568 1.01 0.963,1.05 2073 20745 0.955 1.0 0.956,1.05 1963 19889
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.3221 1.01 0.99,1.03 9366 93681 0.4487 1.05 0.929,1.18 284 2921
519.2 Respiratory complications respiratory Both 0.8204 0.987 0.882,1.1 327 3279 0.7889 0.984 0.877,1.1 310 3127
519.8 Other diseases of respiratory system, NEC respiratory Both 0.3945 1.01 0.988,1.03 8853 88522 0.4677 1.01 0.986,1.03 8410 84975
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.6412 1.03 0.915,1.15 303 3049 0.4487 1.05 0.929,1.18 284 2921
520 Disorders of tooth development digestive Both 0.1892 1.03 0.985,1.08 2038 20354 0.03548 1.05 1.0,1.09 2298 22943
520.1 Hereditary disturbances in tooth structure digestive Both 0.9268 0.986 0.73,1.33 53 530 0.7727 1.05 0.768,1.43 51 519
520.2 Disturbances in tooth eruption digestive Both 0.05888 1.04 0.998,1.09 2356 23539 0.03548 1.05 1.0,1.09 2298 22943
521 Diseases of hard tissues of teeth digestive Both 0.5781 1.01 0.974,1.05 3016 30245 0.6823 1.01 0.97,1.05 2915 29384
521.1 Dental caries digestive Both 0.743 1.01 0.969,1.04 3026 30353 0.6823 1.01 0.97,1.05 2915 29384
522 Diseases of pulp and periapical tissues digestive Both 0.9908 1.0 0.952,1.05 1774 17750 0.2371 0.964 0.908,1.02 1136 11343
522.5 Periapical abscess digestive Both 0.1923 0.961 0.906,1.02 1172 11731 0.2371 0.964 0.908,1.02 1136 11343
523 Gingival and periodontal diseases digestive Both 0.2254 0.969 0.922,1.02 1681 16812 0.0631 0.92 0.843,1.0 543 5416
523.1 Gingivitis digestive Both 0.8551 1.02 0.836,1.24 113 1127 0.8892 0.986 0.804,1.21 107 1085
523.3 Periodontitis (acute or chronic) digestive Both 0.3873 0.974 0.916,1.03 1165 11650 0.0631 0.92 0.843,1.0 543 5416
523.31 Acute periodontitis digestive Both 0.6266 1.02 0.941,1.11 666 6667 0.4365 1.03 0.952,1.12 655 6485
523.32 Chronic periodontitis digestive Both 0.05012 0.918 0.842,1.0 560 5594 0.0631 0.92 0.843,1.0 543 5416
524 Dentofacial anomalies, including malocclusion digestive Both 0.1151 1.09 0.978,1.22 331 3307 0.02884 1.14 1.01,1.29 295 2975
524.3 Anomalies of tooth position/malocclusion digestive Both 0.05012 1.12 1.0,1.26 305 3046 0.02884 1.14 1.01,1.29 295 2975
525 Other diseases of the teeth and supporting structures digestive Both 0.6252 1.01 0.971,1.05 2668 26728 0.2333 0.865 0.681,1.1 72 687
525.2 Atrophy of edentulous alveolar ridge digestive Both 0.157 0.841 0.662,1.07 72 720 0.2333 0.865 0.681,1.1 72 687
526 Diseases of the jaws digestive Both 0.7638 0.99 0.926,1.06 928 9279 0.787 1.02 0.889,1.17 219 2248
526.1 Cysts of the jaws digestive Both 0.6237 0.973 0.87,1.09 329 3289 0.526 0.964 0.861,1.08 319 3180
526.3 Anomalies of jaw size/symmetry digestive Both 0.2438 0.862 0.671,1.11 61 610 0.2559 0.865 0.673,1.11 61 601
526.4 Temporomandibular joint disorders digestive Both 0.3105 1.07 0.939,1.22 240 2406 0.3873 1.06 0.927,1.22 222 2275
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.375 1.06 0.93,1.21 233 2336 0.3873 1.06 0.927,1.22 222 2275
526.5 Inflammatory conditions of jaw digestive Both 0.6668 0.958 0.789,1.16 110 1098 0.4786 0.932 0.766,1.13 107 1057
526.9 Jaw disease NOS digestive Both 0.9817 1.0 0.877,1.14 233 2329 0.787 1.02 0.889,1.17 219 2248
527 Diseases of the salivary glands digestive Both 0.6998 1.02 0.939,1.1 694 6943 0.1282 1.16 0.958,1.41 115 1159
527.1 Hypertrophy of salivary gland digestive Both 0.2642 0.882 0.707,1.1 84 838 0.2825 0.884 0.705,1.11 81 804
527.2 Sialoadenitis digestive Both 0.8433 1.01 0.909,1.12 365 3656 0.9484 1.0 0.9,1.12 351 3517
527.7 Disturbance of salivary secretion digestive Both 0.9772 1.0 0.773,1.3 62 619 0.929 1.01 0.774,1.32 58 596
527.8 Other specified diseases of the salivary glands digestive Both 0.133 1.16 0.957,1.39 120 1200 0.1282 1.16 0.958,1.41 115 1159
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.09772 1.03 0.995,1.06 3873 38741 0.9977 1.0 0.89,1.12 303 3034
528.1 Stomatitis and mucositis digestive Both 0.1186 1.08 0.981,1.19 468 4675 0.2818 0.879 0.695,1.11 78 800
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.05754 1.11 0.997,1.23 389 3884 0.1119 1.09 0.98,1.22 367 3756
528.12 Oral aphthae digestive Both 0.5082 0.927 0.74,1.16 84 840 0.2818 0.879 0.695,1.11 78 800
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.869 1.01 0.87,1.18 179 1790 0.9268 0.993 0.851,1.16 176 1722
528.4 Cysts of oral soft tissues digestive Both 0.6653 0.958 0.791,1.16 122 1219 0.6339 0.948 0.76,1.18 92 909
528.41 Cyst of the salivary gland digestive Both 0.7745 0.969 0.778,1.21 94 940 0.6339 0.948 0.76,1.18 92 909
528.5 Diseases of lips digestive Both 0.05012 1.08 1.0,1.17 681 6813 0.1288 1.07 0.981,1.16 614 6558
528.6 Leukoplakia of oral mucosa digestive Both 0.2415 1.07 0.954,1.2 308 3079 0.2917 1.07 0.946,1.2 293 2971
528.7 Sialolithiasis digestive Both 0.9226 0.994 0.887,1.11 314 3138 0.9977 1.0 0.89,1.12 303 3034
529 Diseases and other conditions of the tongue digestive Both 0.6577 1.01 0.955,1.08 1232 12312 0.3373 1.06 0.938,1.2 285 2872
529.1 Glossitis digestive Both 0.2553 1.07 0.95,1.21 299 2986 0.3373 1.06 0.938,1.2 285 2872
530 Diseases of esophagus digestive Both 0.008318 1.02 1.0,1.03 33453 279172 0.05129 1.05 1.0,1.1 1997 20131
530.1 Esophagitis, GERD and related diseases digestive Both 0.01905 1.01 1.0,1.03 31253 272429 0.8147 0.998 0.977,1.02 10044 100616
530.11 GERD digestive Both 0.2234 1.01 0.995,1.02 22633 225879 0.1315 1.01 0.997,1.03 21699 217582
530.12 Ulcer of esophagus digestive Both 0.8492 1.0 0.975,1.03 5203 52068 0.8147 1.0 0.975,1.03 4995 49866
530.14 Reflux esophagitis digestive Both 0.5929 0.994 0.975,1.01 10444 104493 0.8147 0.998 0.977,1.02 10044 100616
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.1262 1.04 0.989,1.09 1681 16808 0.2477 1.03 0.979,1.08 1608 16163
530.3 Stricture and stenosis of esophagus digestive Both 0.5212 1.02 0.969,1.07 1869 18684 0.5458 1.02 0.967,1.07 1786 17875
530.5 Disorders of esophageal motility digestive Both 0.8222 0.991 0.913,1.08 635 6365 0.9727 0.999 0.918,1.09 601 6138
530.6 Diverticulum of esophagus, acquired digestive Both 0.7691 0.976 0.827,1.15 153 1527 0.8531 0.984 0.831,1.17 145 1452
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.4178 0.955 0.854,1.07 341 3416 0.3802 0.95 0.848,1.07 326 3305
530.9 Heartburn digestive Both 0.1 1.04 0.993,1.09 2087 20881 0.05129 1.05 1.0,1.1 1997 20131
531 Peptic ulcer (excl. esophageal) digestive Both 0.4102 1.01 0.986,1.04 7103 71066 0.5888 1.03 0.929,1.14 401 4112
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.7362 1.01 0.935,1.1 637 6374 0.6622 1.02 0.938,1.11 615 6090
531.2 Gastric ulcer digestive Both 0.8913 1.0 0.971,1.03 4091 40941 0.8892 1.0 0.97,1.04 3903 39233
531.3 Duodenal ulcer digestive Both 0.6823 0.992 0.955,1.03 2999 30005 0.7161 0.993 0.955,1.03 2863 28826
531.4 Peptic ulcer, site unspecified digestive Both 0.257 1.06 0.959,1.17 427 4268 0.5888 1.03 0.929,1.14 401 4112
532 Dysphagia digestive Both 0.1 1.02 0.996,1.05 6427 64329 0.1045 1.02 0.995,1.05 6131 61937
535 Gastritis and duodenitis digestive Both 0.0302 1.01 1.0,1.03 28078 261548 0.507 0.936 0.771,1.14 115 1143
535.1 Acute gastritis digestive Both 0.6683 1.01 0.955,1.07 1183 11833 0.3828 1.03 0.967,1.09 1128 11387
535.2 Atrophic gastritis digestive Both 0.3926 1.05 0.941,1.17 370 3687 0.4581 1.04 0.934,1.16 359 3542
535.6 Duodenitis digestive Both 0.9397 0.999 0.976,1.02 7592 75928 0.9977 1.0 0.976,1.02 7288 72951
535.8 Other specified gastritis digestive Both 0.5808 0.994 0.971,1.02 8071 80763 0.6823 0.995 0.972,1.02 7720 77589
535.9 Gastritis and duodenitis, NOS digestive Both 0.4345 0.927 0.766,1.12 120 1191 0.507 0.936 0.771,1.14 115 1143
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.1596 1.09 0.966,1.24 259 2576 0.1799 1.09 0.961,1.23 253 2478
537 Other disorders of stomach and duodenum digestive Both 0.1183 1.03 0.993,1.07 3391 33907 0.3048 1.02 0.983,1.06 3255 32549
540 Appendiceal conditions digestive Both 0.1679 0.974 0.939,1.01 3088 30890 0.3404 0.98 0.941,1.02 2522 25319
540.1 Appendicitis digestive Both 0.1888 0.975 0.938,1.01 2895 28963 0.3404 0.98 0.941,1.02 2522 25319
540.11 Acute appendicitis digestive Both 0.3062 0.979 0.94,1.02 2601 26019 0.3404 0.98 0.941,1.02 2522 25319
550 Abdominal hernia digestive Both 0.1057 1.01 0.998,1.02 45429 282640 0.389 1.02 0.98,1.05 3256 33020
550.1 Inguinal hernia digestive Both 0.5585 0.995 0.979,1.01 15794 123247 0.5093 0.994 0.977,1.01 15004 118484
550.2 Diaphragmatic hernia digestive Both 0.001072 1.02 1.01,1.03 26494 238953 0.00257 1.02 1.01,1.03 25386 230230
550.3 Femoral hernia digestive Both 0.5082 0.972 0.895,1.06 651 6504 0.7762 0.988 0.908,1.07 630 6283
550.4 Umbilical hernia digestive Both 0.7907 0.995 0.962,1.03 3705 37072 0.8395 0.996 0.962,1.03 3552 35769
550.5 Ventral hernia digestive Both 0.236 1.02 0.986,1.06 3435 34338 0.389 1.02 0.98,1.05 3256 33020
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.879 1.0 0.972,1.03 4444 44442 0.7244 1.02 0.928,1.11 507 5178
555.1 Regional enteritis digestive Both 0.673 0.989 0.941,1.04 1734 17340 0.8913 0.996 0.947,1.05 1647 16761
555.2 Ulcerative colitis digestive Both 0.7568 1.01 0.97,1.04 3178 31786 0.7244 1.02 0.928,1.11 507 5178
555.21 Ulcerative colitis (chronic) digestive Both 0.8414 1.01 0.923,1.1 538 5382 0.7244 1.02 0.928,1.11 507 5178
556 Ulceration of the lower GI tract digestive Both 0.6209 1.02 0.953,1.08 1055 10592 0.7603 0.987 0.908,1.07 636 6488
556.1 Ulceration of intestine digestive Both 0.867 0.993 0.915,1.08 670 6714 0.7603 0.987 0.908,1.07 636 6488
557 Intestinal malabsorption (non-celiac) digestive Both 0.5117 1.04 0.924,1.17 299 2987 0.3273 1.02 0.976,1.08 1754 17742
557.1 Celiac disease digestive Both 0.3311 1.02 0.976,1.07 1837 18388 0.3273 1.02 0.976,1.08 1754 17742
558 Noninfectious gastroenteritis digestive Both 0.01445 1.02 1.0,1.04 15492 155105 0.01072 1.02 1.01,1.04 14851 149700
559 Ileostomy status digestive Both 0.1282 0.961 0.913,1.01 1656 16541 0.0955 0.957 0.908,1.01 1568 15861
560 Intestinal obstruction without mention of hernia digestive Both 0.5047 1.01 0.979,1.04 3936 39337 0.4943 1.01 0.977,1.05 3211 32274
560.1 Paralytic ileus digestive Both 0.2366 1.06 0.965,1.16 523 5231 0.4977 1.03 0.94,1.14 484 4994
560.2 Impaction of intestine digestive Both 0.2404 0.926 0.815,1.05 268 2671 0.3266 0.937 0.823,1.07 259 2567
560.3 Peritoneal or intestinal adhesions digestive Both 0.2748 1.04 0.969,1.12 832 8317 0.1256 1.06 0.984,1.14 793 8013
560.4 Other intestinal obstruction digestive Both 0.6683 1.01 0.973,1.04 3358 33550 0.4943 1.01 0.977,1.05 3211 32274
561 Symptoms involving digestive system digestive Both 0.4634 1.01 0.99,1.02 15772 157686 0.1384 1.04 0.988,1.09 1618 16266
561.1 Diarrhea digestive Both 0.3597 1.04 0.952,1.15 466 4653 0.4064 1.04 0.947,1.14 449 4470
561.2 Flatulence digestive Both 0.1816 1.03 0.984,1.09 1687 16859 0.1384 1.04 0.988,1.09 1618 16266
562 Diverticulosis and diverticulitis digestive Both 0.0309 1.01 1.0,1.03 26714 211692 0.07762 1.01 0.999,1.03 25400 203835
562.1 Diverticulosis digestive Both 0.0302 1.01 1.0,1.03 26672 211642 0.07762 1.01 0.999,1.03 25400 203835
563 Constipation digestive Both 0.975 1.0 0.98,1.02 10314 103140 0.8185 1.0 0.982,1.02 9865 99351
564 Functional digestive disorders digestive Both 0.2624 1.01 0.994,1.02 21639 209949 0.06166 1.02 0.999,1.03 14472 145762
564.1 Irritable Bowel Syndrome digestive Both 0.3273 1.01 0.986,1.04 5508 55117 0.2844 1.02 0.987,1.04 5332 53392
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.8091 0.994 0.944,1.05 1645 16457 0.7962 0.993 0.942,1.05 1559 15862
564.9 Personal history of diseases of digestive system digestive Both 0.1247 1.01 0.996,1.03 15186 151648 0.06166 1.02 0.999,1.03 14472 145762
565 Anal and rectal conditions digestive Both 0.5728 0.995 0.978,1.01 14744 147535 0.9183 1.0 0.977,1.03 6985 70625
565.1 Anal and rectal polyp digestive Both 0.5702 1.01 0.983,1.03 7351 73533 0.9183 1.0 0.977,1.03 6985 70625
567 Peritonitis and retroperitoneal infections digestive Both 0.4797 0.976 0.913,1.04 929 9293 0.4932 0.976 0.911,1.05 887 8971
568 Other disorders of peritoneum digestive Both 0.5346 1.01 0.976,1.05 3262 32602 0.5984 1.01 0.973,1.05 2985 29893
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.6761 1.01 0.971,1.05 3101 30987 0.5984 1.01 0.973,1.05 2985 29893
569 Other disorders of intestine digestive Both 0.8551 0.997 0.966,1.03 4192 41922 0.5082 0.968 0.879,1.07 463 4668
569.1 Toxic gastroenteritis and colitis digestive Both 0.867 0.986 0.833,1.17 148 1479 0.7112 0.968 0.813,1.15 138 1405
569.2 Gastrointestinal complications digestive Both 0.3581 0.957 0.871,1.05 486 4868 0.5082 0.968 0.879,1.07 463 4668
571 Chronic liver disease and cirrhosis digestive Both 0.07586 1.04 0.996,1.08 2957 29628 0.271 1.05 0.961,1.15 498 5090
571.5 Other chronic nonalcoholic liver disease digestive Both 0.5794 1.01 0.964,1.07 1689 16917 8.128E-4 0.707 0.578,0.866 105 1102
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.008511 0.768 0.631,0.935 113 1139 8.128E-4 0.707 0.578,0.866 105 1102
571.6 Primary biliary cirrhosis digestive Both 0.09333 1.12 0.982,1.27 257 2568 0.1007 1.12 0.979,1.28 242 2459
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.114 1.05 0.987,1.13 976 9804 0.271 1.05 0.961,1.15 498 5090
571.81 Portal hypertension digestive Both 0.1167 1.07 0.982,1.17 528 5285 0.271 1.05 0.961,1.15 498 5090
572 Ascites (non malignant) digestive Both 0.4943 1.02 0.967,1.07 1544 15454 0.4909 1.02 0.966,1.08 1463 14835
573 Other disorders of liver digestive Both 0.6383 1.01 0.96,1.07 1496 14982 0.6918 1.03 0.891,1.19 198 1991
573.2 Liver replaced by transplant digestive Both 0.618 1.05 0.858,1.29 96 960 0.5861 1.07 0.845,1.35 72 924
573.3 Hepatomegaly digestive Both 0.4395 0.954 0.846,1.08 297 2968 0.415 0.95 0.84,1.07 284 2836
573.5 Jaundice (not of newborn) digestive Both 0.8531 0.993 0.927,1.06 896 8955 0.975 1.0 0.933,1.07 859 8589
573.7 Abnormal results of function study of liver digestive Both 0.929 1.0 0.967,1.04 3454 34597 0.9078 1.0 0.967,1.04 3288 33291
573.9 Abnormal serum enzyme levels digestive Both 0.4786 1.05 0.914,1.21 209 2089 0.6918 1.03 0.891,1.19 198 1991
574 Cholelithiasis and cholecystitis digestive Both 0.8395 0.998 0.982,1.01 15607 156123 0.8433 1.0 0.965,1.05 2652 26482
574.1 Cholelithiasis digestive Both 0.7362 0.997 0.979,1.01 13549 135537 0.3819 0.987 0.96,1.02 5208 52363
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.9099 1.0 0.951,1.06 1506 15072 0.7178 0.99 0.938,1.04 1441 14523
574.12 Cholelithiasis with other cholecystitis digestive Both 0.3516 0.987 0.96,1.01 5429 54289 0.3819 0.987 0.96,1.02 5208 52363
574.2 Calculus of bile duct digestive Both 0.6412 1.01 0.97,1.05 2620 26191 0.7047 1.01 0.968,1.05 2524 25210
574.3 Cholecystitis without cholelithiasis digestive Both 0.9268 1.0 0.963,1.04 2748 27523 0.8433 1.0 0.965,1.05 2652 26482
575 Other biliary tract disease digestive Both 0.3273 1.02 0.983,1.05 3867 38724 0.8375 0.988 0.883,1.11 329 3325
575.1 Cholangitis digestive Both 0.9247 0.996 0.908,1.09 495 4945 0.9376 0.996 0.907,1.09 472 4722
575.2 Obstruction of bile duct digestive Both 0.191 0.952 0.883,1.03 774 7756 0.1489 0.946 0.876,1.02 741 7436
575.6 Cholesterolosis of gallbladder digestive Both 0.9078 0.994 0.904,1.09 458 4577 0.871 0.992 0.9,1.09 442 4405
575.7 Other disorders of gallbladder digestive Both 0.09333 1.05 0.992,1.11 1408 14107 0.1005 1.05 0.991,1.11 1352 13624
575.8 Other disorders of biliary tract digestive Both 0.02344 1.08 1.01,1.15 1036 10367 0.01445 1.09 1.02,1.16 991 9974
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.9376 0.996 0.892,1.11 348 3488 0.8375 0.988 0.883,1.11 329 3325
577 Diseases of pancreas digestive Both 0.3784 1.02 0.978,1.06 2668 26677 0.2786 0.941 0.844,1.05 346 3489
577.1 Acute pancreatitis digestive Both 0.4227 1.02 0.973,1.07 1996 19962 0.5781 1.01 0.967,1.06 1911 19199
577.2 Chronic pancreatitis digestive Both 0.2685 1.05 0.961,1.15 515 5149 0.2056 1.06 0.968,1.16 501 4968
577.3 Cyst and pseudocyst of pancreas digestive Both 0.1549 0.925 0.832,1.03 365 3650 0.2786 0.941 0.844,1.05 346 3489
578 Gastrointestinal hemorrhage digestive Both 0.8913 1.0 0.987,1.02 20626 206278 0.9572 0.999 0.971,1.03 5065 50949
578.1 Hematemesis digestive Both 0.7328 1.01 0.962,1.06 1958 19564 0.7244 1.01 0.962,1.06 1885 18839
578.2 Blood in stool digestive Both 0.3819 0.982 0.944,1.02 2626 26283 0.5093 0.986 0.947,1.03 2507 25232
578.8 Hemorrhage of rectum and anus digestive Both 0.4018 1.01 0.99,1.03 13073 130745 0.2917 1.01 0.992,1.03 12489 126197
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.7907 1.0 0.976,1.03 5275 52787 0.9572 0.999 0.971,1.03 5065 50949
579 Other symptoms involving abdomen and pelvis digestive Both 0.1945 1.04 0.982,1.09 1548 15498 0.4335 1.02 0.969,1.08 1580 15919
579.2 Splenomegaly digestive Both 0.9162 1.01 0.91,1.11 422 4246 0.9931 1.0 0.901,1.11 388 4073
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.6152 1.01 0.963,1.07 1654 16540 0.4335 1.02 0.969,1.08 1580 15919
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.4406 1.02 0.968,1.08 1531 15350 0.7015 1.03 0.897,1.18 230 2431
580.1 Glomerulonephritis genitourinary Both 0.6471 1.02 0.952,1.08 1052 10544 0.1871 1.05 0.976,1.13 811 8345
580.11 Proliferative glomerulonephritis genitourinary Both 0.1914 0.855 0.676,1.08 74 738 0.3069 0.88 0.689,1.12 68 704
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.2328 0.899 0.755,1.07 135 1360 0.2642 0.902 0.752,1.08 123 1310
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.1968 1.05 0.976,1.12 876 8769 0.1871 1.05 0.976,1.13 811 8345
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.4721 1.04 0.941,1.14 468 4697 0.5649 1.03 0.933,1.14 447 4504
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.7079 1.03 0.9,1.17 246 2460 0.7015 1.03 0.897,1.18 230 2431
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.618 1.03 0.908,1.18 253 2529 0.7015 1.03 0.897,1.18 230 2431
585 Renal failure genitourinary Both 0.7396 1.0 0.98,1.03 6967 69751 0.8222 1.01 0.916,1.12 432 4769
585.1 Acute renal failure genitourinary Both 0.869 0.997 0.967,1.03 4527 45305 0.6516 0.993 0.962,1.02 4284 43229
585.2 Renal failure NOS genitourinary Both 0.4498 1.02 0.967,1.08 1460 14625 0.4898 1.02 0.964,1.08 1365 14015
585.3 Chronic renal failure [CKD] genitourinary Both 0.826 0.996 0.956,1.04 2644 26484 0.8222 1.01 0.916,1.12 432 4769
585.31 Renal dialysis genitourinary Both 0.3524 1.04 0.953,1.15 496 4955 0.8222 1.01 0.916,1.12 432 4769
586 Other disorders of the kidney and ureters genitourinary Both 0.4943 1.01 0.977,1.05 3355 33580 0.9795 1.0 0.933,1.07 858 8784
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.5649 1.04 0.901,1.21 208 2089 0.7691 1.03 0.868,1.21 163 1728
586.11 Small kidney genitourinary Both 0.4064 1.07 0.912,1.26 179 1799 0.7691 1.03 0.868,1.21 163 1728
586.2 Cyst of kidney, acquired genitourinary Both 0.9908 1.0 0.944,1.06 1257 12582 0.9183 1.0 0.945,1.07 1187 12036
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.7379 1.04 0.832,1.3 80 799 0.9462 0.992 0.79,1.25 74 759
586.4 Stricture/obstruction of ureter genitourinary Both 0.7244 1.01 0.946,1.08 910 9122 0.9795 1.0 0.933,1.07 858 8784
587 Kidney replaced by transpant genitourinary Both 0.7745 0.985 0.886,1.09 368 3683 0.4285 0.954 0.848,1.07 290 3574
588 Disorders resulting from impaired renal function genitourinary Both 0.9376 0.991 0.802,1.23 99 990 0.9354 0.991 0.796,1.23 91 944
589 Abnormal results of function study of kidney genitourinary Both 0.6792 1.04 0.863,1.25 116 1158 0.6839 1.04 0.857,1.27 106 1108
590 Pyelonephritis genitourinary Both 0.1279 0.957 0.905,1.01 1328 13285 0.06918 0.948 0.895,1.0 1271 12844
591 Urinary tract infection genitourinary Both 0.354 1.01 0.99,1.03 12400 123937 0.6546 1.0 0.985,1.02 11818 119050
592 Cystitis and urethritis genitourinary Both 0.4256 1.02 0.978,1.05 2966 29661 0.7727 0.976 0.83,1.15 158 1596
592.1 Cystitis genitourinary Both 0.3443 1.02 0.981,1.06 2904 29035 0.9616 0.997 0.872,1.14 241 2417
592.11 Acute cystitis genitourinary Both 0.7447 0.971 0.814,1.16 138 1372 0.618 0.955 0.795,1.15 127 1335
592.12 Chronic cystitis genitourinary Both 0.1762 1.05 0.979,1.12 889 8890 0.4487 1.03 0.958,1.1 836 8534
592.13 Chronic interstitial cystitis genitourinary Both 0.9141 1.01 0.883,1.15 249 2486 0.9616 0.997 0.872,1.14 241 2417
592.2 Urethritis and urethral syndrome genitourinary Both 0.5768 0.955 0.814,1.12 165 1662 0.7727 0.976 0.83,1.15 158 1596
593 Hematuria genitourinary Both 0.04898 1.02 1.0,1.03 16068 160204 0.157 1.01 0.995,1.03 15289 153863
594 Urinary calculus genitourinary Both 0.04169 1.03 1.0,1.05 6376 63761 0.3192 1.02 0.977,1.07 1974 19769
594.1 Calculus of kidney genitourinary Both 0.2455 1.02 0.985,1.06 3175 31757 0.1718 1.03 0.989,1.07 3031 30499
594.2 Calculus of lower urinary tract genitourinary Both 0.1945 1.05 0.975,1.13 776 7764 0.2466 1.05 0.969,1.13 726 7412
594.3 Calculus of ureter genitourinary Both 0.9506 0.999 0.957,1.04 2401 24024 0.9226 1.0 0.96,1.05 2301 23133
594.8 Renal colic genitourinary Both 0.3357 1.02 0.977,1.07 2050 20500 0.3192 1.02 0.977,1.07 1974 19769
595 Hydronephrosis genitourinary Both 0.0871 0.96 0.916,1.01 1936 19395 0.1189 0.962 0.917,1.01 1845 18662
596 Other disorders of bladder genitourinary Both 0.4305 1.01 0.988,1.03 9771 97778 0.4853 0.982 0.933,1.03 1588 15943
596.1 Bladder neck obstruction genitourinary Both 0.2541 1.03 0.981,1.08 1969 19690 0.2148 1.03 0.982,1.08 1860 18725
596.5 Functional disorders of bladder genitourinary Both 0.6637 0.989 0.941,1.04 1658 16572 0.4853 0.982 0.933,1.03 1588 15943
597 Other disorders of urethra and urinary tract genitourinary Both 0.7691 1.0 0.972,1.04 3913 39135 0.07943 0.809 0.639,1.02 77 756
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.9036 0.998 0.963,1.03 3317 33137 0.695 0.993 0.957,1.03 3178 31772
597.2 Urinary complications NEC genitourinary Both 0.0871 0.814 0.643,1.03 78 778 0.07943 0.809 0.639,1.02 77 756
598 Abnormal findings on examination of urine genitourinary Both 0.8166 1.0 0.97,1.04 3528 35302 0.8453 0.988 0.878,1.11 290 2891
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.7328 0.98 0.873,1.1 304 3035 0.8453 0.988 0.878,1.11 290 2891
599 Other symptoms/disorders or the urinary system genitourinary Both 0.6531 0.997 0.982,1.01 18428 184311 0.9528 0.999 0.951,1.05 1827 18321
599.1 Urinary obstruction genitourinary Both 0.4436 0.942 0.809,1.1 166 1670 0.7889 0.979 0.835,1.15 156 1599
599.2 Retention of urine genitourinary Both 0.08511 1.02 0.997,1.05 6718 67168 0.07244 1.02 0.998,1.05 6357 64017
599.3 Dysuria genitourinary Both 0.3954 1.03 0.967,1.09 1196 11967 0.6266 1.02 0.955,1.08 1151 11522
599.4 Urinary incontinence genitourinary Both 0.1581 0.984 0.963,1.01 8748 87477 0.1871 0.985 0.963,1.01 8412 84411
599.5 Frequency of urination and polyuria genitourinary Both 0.5957 1.01 0.977,1.04 4018 40144 0.7311 1.01 0.973,1.04 3818 38513
599.6 Oliguria and anuria genitourinary Both 0.5559 0.943 0.775,1.15 105 1059 0.3327 0.903 0.736,1.11 94 1001
599.8 Other symptoms involving urinary system genitourinary Both 0.7691 1.04 0.808,1.33 62 620 0.865 1.02 0.792,1.32 58 599
599.9 Other abnormality of urination genitourinary Both 0.8241 1.01 0.959,1.05 1913 19151 0.9528 0.999 0.951,1.05 1827 18321
600 Hyperplasia of prostate genitourinary Male 0.009333 1.03 1.01,1.05 11093 87892 0.01905 1.02 1.0,1.05 10412 83841
601 Inflammatory diseases of prostate genitourinary Male 0.9204 0.998 0.953,1.04 2081 20818 0.9705 0.998 0.884,1.13 287 2895
601.1 Prostatitis genitourinary Male 0.9397 1.0 0.951,1.06 1563 15644 0.1734 1.05 0.979,1.13 851 8659
601.11 Acute prostatitis genitourinary Male 0.6887 0.973 0.851,1.11 234 2358 0.3639 0.937 0.815,1.08 216 2261
601.12 Chronic prostatitis genitourinary Male 0.1496 1.05 0.982,1.12 910 9089 0.1734 1.05 0.979,1.13 851 8659
601.3 Orchitis and epididymitis genitourinary Male 0.857 0.976 0.75,1.27 59 588 0.859 0.976 0.749,1.27 58 570
601.4 Balanoposthitis genitourinary Male 0.9886 0.999 0.883,1.13 287 2864 0.8872 1.01 0.889,1.14 277 2741
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.8128 0.986 0.876,1.11 303 3019 0.9705 0.998 0.884,1.13 287 2895
602 Other disorders of prostate genitourinary Male 0.3459 1.03 0.971,1.09 1341 13408 0.4786 1.02 0.963,1.08 1263 12737
603 Other disorders of testis genitourinary Male 0.9016 0.997 0.954,1.04 2150 21512 0.8433 0.994 0.938,1.05 1260 12810
603.1 Hydrocele genitourinary Male 0.5821 0.984 0.93,1.04 1339 13402 0.8433 0.994 0.938,1.05 1260 12810
604 Disorders of penis genitourinary Male 0.6012 1.01 0.974,1.05 3280 32779 0.2673 1.02 0.983,1.07 2632 26180
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.3733 1.02 0.978,1.06 2719 27172 0.2673 1.02 0.983,1.07 2632 26180
605 Erectile dysfunction [ED] genitourinary Male 0.2286 1.08 0.953,1.22 278 2800 0.3741 1.06 0.933,1.2 263 2671
608 Other disorders of male genital organs genitourinary Male 0.8375 1.0 0.966,1.04 2822 28236 0.9506 0.999 0.96,1.04 2695 27102
609 Male infertility and abnormal spermatozoa genitourinary Male 0.984 1.0 0.873,1.15 214 2138 0.7295 1.03 0.866,1.23 149 1592
609.1 Infertility, male genitourinary Male 0.1552 0.839 0.659,1.07 63 638 0.1486 0.833 0.65,1.07 60 616
609.2 Abnormal spermatozoa genitourinary Male 0.2924 1.09 0.927,1.28 169 1698 0.7295 1.03 0.866,1.23 149 1592
610 Benign mammary dysplasias genitourinary Female 0.003162 1.06 1.02,1.11 2482 24809 0.875 0.994 0.918,1.08 663 6751
610.1 Cystic mastopathy genitourinary Female 0.00871 1.1 1.02,1.17 925 9250 0.009772 1.1 1.02,1.17 888 8970
610.2 Fibroadenosis of breast genitourinary Female 0.004898 1.19 1.05,1.33 306 3057 0.01023 1.17 1.04,1.33 287 2967
610.3 Fibrosclerosis of breast genitourinary Female 0.2089 1.08 0.957,1.22 302 3018 0.2366 1.08 0.952,1.22 289 2922
610.4 Benign neoplasm of breast genitourinary Female 0.1849 1.04 0.982,1.1 1388 13865 0.1923 1.04 0.981,1.1 1350 13484
610.8 Other specified benign mammary dysplasias genitourinary Female 0.8995 0.995 0.921,1.08 696 6954 0.875 0.994 0.918,1.08 663 6751
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.1038 1.04 0.991,1.1 1574 15731 0.1603 1.04 0.985,1.1 1458 14734
611.1 Abnormal mammogram genitourinary Both 0.1905 1.19 0.916,1.55 57 569 ,
611.3 Lump or mass in breast genitourinary Both 0.1626 1.04 0.985,1.09 1522 15213 0.1603 1.04 0.985,1.1 1458 14734
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.5521 0.979 0.914,1.05 887 8871 0.6622 0.947 0.74,1.21 67 705
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.7464 0.988 0.921,1.06 849 8490 0.5998 0.981 0.913,1.05 824 8245
612.3 Congenital anomalies of breast genitourinary Both 0.5212 0.925 0.728,1.18 72 719 0.6622 0.947 0.74,1.21 67 705
613 Other nonmalignant breast conditions genitourinary Both 0.1222 1.04 0.989,1.09 1651 16519 0.1791 1.08 0.964,1.22 316 3194
613.1 Inflammatory disease of breast genitourinary Both 0.1189 1.06 0.984,1.15 720 7210 0.1675 1.06 0.977,1.14 692 6995
613.5 Mastodynia genitourinary Both 0.5395 1.07 0.853,1.35 77 768 0.6486 1.06 0.832,1.34 73 745
613.7 Other signs and symptoms in breast genitourinary Both 0.03311 1.09 1.01,1.18 702 7013 0.03631 1.09 1.01,1.18 680 6804
613.8 Other specified disorders of breast genitourinary Both 0.2208 1.07 0.958,1.2 327 3278 0.1791 1.08 0.964,1.22 316 3194
613.9 Breast disorder NOS genitourinary Both 0.9863 1.0 0.872,1.15 207 2069 ,
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.6808 1.01 0.979,1.03 5711 57118 0.0302 0.866 0.76,0.987 263 2655
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.2004 1.03 0.986,1.07 2538 25363 0.1432 1.03 0.99,1.08 2462 24769
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.618 0.982 0.914,1.06 830 8308 0.4613 0.959 0.857,1.07 344 3424
614.31 Acute inflammatory pelvic disease genitourinary Female 0.6486 0.942 0.729,1.22 61 608 0.695 0.95 0.735,1.23 61 593
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.3342 0.952 0.861,1.05 422 4221 0.3451 0.952 0.86,1.05 409 4117
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.5284 0.965 0.863,1.08 351 3510 0.4613 0.959 0.857,1.07 344 3424
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.8531 0.988 0.872,1.12 277 2775 0.7261 0.977 0.861,1.11 267 2713
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.8054 0.995 0.956,1.04 2601 26023 0.0302 0.866 0.76,0.987 263 2655
614.51 Cervicitis and endocervicitis genitourinary Female 0.04169 1.06 1.0,1.12 1318 13189 0.04467 1.06 1.0,1.12 1276 12802
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.02884 0.896 0.813,0.989 428 4273 0.01549 0.884 0.799,0.977 410 4147
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.929 1.0 0.931,1.08 755 7574 0.9462 1.0 0.929,1.08 733 7382
614.54 Abscess or ulceration of vulva genitourinary Female 0.0309 0.868 0.764,0.987 274 2737 0.0302 0.866 0.76,0.987 263 2655
615 Endometriosis genitourinary Female 0.05888 1.03 0.999,1.07 4029 40284 0.05129 1.03 1.0,1.07 3926 39388
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.156 1.09 0.968,1.23 304 3037 0.1799 1.09 0.962,1.23 286 2948
618 Genital prolapse genitourinary Female 0.6471 0.996 0.977,1.01 11689 116878 0.4721 1.03 0.951,1.11 657 6546
618.1 Prolapse of vaginal walls genitourinary Female 0.8531 1.0 0.979,1.03 7392 73940 0.7656 1.0 0.98,1.03 7137 71257
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.2624 0.984 0.957,1.01 5393 53918 0.3206 0.986 0.958,1.01 5202 51893
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.2972 0.953 0.87,1.04 512 5125 0.3499 0.957 0.872,1.05 497 4959
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.492 1.03 0.951,1.11 680 6794 0.4721 1.03 0.951,1.11 657 6546
619 Noninflammatory female genital disorders genitourinary Female 0.6397 0.995 0.973,1.02 8726 87297 0.9616 0.999 0.943,1.06 1296 13081
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.1714 0.948 0.878,1.02 729 7284 0.05888 0.928 0.859,1.0 710 7086
619.2 Disorders of uterus, NEC genitourinary Female 0.2972 1.02 0.983,1.06 3324 33273 0.2851 1.02 0.984,1.06 3196 32240
619.3 Noninflammatory disorders of cervix genitourinary Female 0.9441 1.0 0.963,1.04 2860 28608 0.8974 0.997 0.959,1.04 2772 27834
619.4 Noninflammatory disorders of vagina genitourinary Female 0.1905 0.968 0.922,1.02 1768 17669 0.2698 0.972 0.925,1.02 1706 17148
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.9333 0.998 0.943,1.06 1350 13489 0.9616 0.999 0.943,1.06 1296 13081
620 Dysplasia of female genital organs genitourinary Female 0.8279 1.03 0.806,1.31 72 720 0.7745 1.04 0.81,1.33 68 700
621 Endometrial hyperplasia genitourinary Female 0.246 1.04 0.975,1.1 1129 11294 0.2864 1.03 0.972,1.1 1084 10924
622 Polyp of female genital organs genitourinary Female 0.1694 1.01 0.994,1.03 10480 104803 0.1611 1.03 0.99,1.06 3334 33340
622.1 Polyp of corpus uteri genitourinary Female 0.2438 1.01 0.991,1.04 7857 78601 0.2594 1.01 0.99,1.04 7594 76215
622.2 Mucous polyp of cervix genitourinary Female 0.1901 1.02 0.989,1.06 3442 34387 0.1611 1.03 0.99,1.06 3334 33340
623 Hypertrophy of female genital organs genitourinary Female 0.07762 1.05 0.994,1.12 1268 12684 0.1552 1.04 0.984,1.11 1227 12348
624 Symptoms involving female genital tract genitourinary Female 0.7709 0.989 0.92,1.06 797 7961 0.139 0.98 0.953,1.01 5669 56746
624.1 Dystrophy of female genital tract genitourinary Female 0.2858 0.929 0.813,1.06 237 2365 0.1932 0.913 0.796,1.05 227 2273
624.2 Atrophy of female genital tract genitourinary Female 0.778 0.986 0.895,1.09 440 4398 0.7816 0.986 0.893,1.09 421 4237
624.9 stress incontinence, female genitourinary Female 0.1021 0.978 0.952,1.0 5865 58634 0.139 0.98 0.953,1.01 5669 56746
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.03981 1.04 1.0,1.08 2876 28740 0.08913 1.05 0.992,1.12 1146 11616
625.1 Dyspareunia genitourinary Female 0.1059 1.05 0.99,1.11 1188 11891 0.08913 1.05 0.992,1.12 1146 11616
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.125 1.01 0.996,1.03 16168 115018 0.002455 1.09 1.03,1.15 1342 13407
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.3199 1.01 0.991,1.03 14110 109918 0.5559 1.01 0.977,1.04 3707 37196
626.11 Absent or infrequent menstruation genitourinary Female 0.7816 1.03 0.845,1.25 109 1099 0.7244 1.04 0.848,1.27 104 1083
626.12 Excessive or frequent menstruation genitourinary Female 0.414 1.01 0.988,1.03 9727 91749 0.3945 1.01 0.988,1.03 9502 89743
626.13 Irregular menstrual cycle genitourinary Female 0.2265 1.03 0.982,1.08 1985 19829 0.235 1.03 0.982,1.08 1946 19327
626.14 Irregular menstrual bleeding genitourinary Female 0.4732 1.01 0.979,1.05 3804 38021 0.5559 1.01 0.977,1.04 3707 37196
626.2 Dysmenorrhea genitourinary Female 0.4842 1.02 0.969,1.07 1778 17767 0.9226 1.0 0.954,1.05 1721 17429
626.4 Premenstrual tension syndromes genitourinary Female 0.7047 0.97 0.829,1.14 159 1587 0.6761 0.967 0.825,1.13 157 1559
626.8 Infertility, female genitourinary Female 0.001549 1.09 1.03,1.16 1362 13613 0.002455 1.09 1.03,1.15 1342 13407
627 Menopausal and postmenopausal disorders genitourinary Female 0.6546 1.0 0.985,1.03 10392 103948 0.5984 0.969 0.86,1.09 303 3005
627.1 Postmenopausal bleeding genitourinary Female 0.6266 1.01 0.984,1.03 9042 90439 0.8551 1.0 0.98,1.02 8683 87219
627.2 Symptomatic menopause genitourinary Female 0.4256 0.941 0.809,1.09 183 1826 0.547 0.953 0.816,1.11 171 1777
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.6397 1.01 0.954,1.08 1111 11115 0.5284 1.02 0.958,1.09 1066 10655
627.4 Premenopausal menorrhagia genitourinary Female 0.5559 0.965 0.858,1.09 310 3097 0.5984 0.969 0.86,1.09 303 3005
628 Ovarian cyst genitourinary Female 0.2449 1.02 0.988,1.05 4747 47482 0.2667 1.02 0.987,1.05 4598 46329
634 Miscarriage; stillbirth pregnancy complications Female 0.4989 1.01 0.981,1.04 5218 36422 0.3656 1.05 0.94,1.18 326 3253
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.1875 1.04 0.98,1.11 1136 11300 0.1622 1.04 0.983,1.11 1118 11148
634.3 Ectopic pregnancy pregnancy complications Female 0.3828 1.05 0.938,1.18 331 3305 0.3656 1.05 0.94,1.18 326 3253
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.8954 0.997 0.952,1.04 1974 17372 0.5534 1.02 0.961,1.08 1241 12158
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.3334 0.966 0.902,1.04 866 8614 0.235 0.958 0.894,1.03 849 8501
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.3776 1.03 0.969,1.09 1270 12306 0.5534 1.02 0.961,1.08 1241 12158
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 1.0 1.0 0.958,1.04 2347 19972 0.6109 0.984 0.924,1.05 1067 10610
636.2 Early onset of delivery pregnancy complications Female 0.7798 1.01 0.932,1.1 617 6144 0.9397 1.0 0.923,1.09 603 6060
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.6194 0.984 0.925,1.05 1082 10766 0.6109 0.984 0.924,1.05 1067 10610
638 Other high-risk pregnancy pregnancy complications Female 0.9931 1.0 0.789,1.27 70 700 0.9954 1.0 0.789,1.27 70 688
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.3451 1.03 0.968,1.1 1110 11074 0.3819 1.05 0.938,1.18 303 3021
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.3899 1.05 0.937,1.18 307 3058 0.3819 1.05 0.938,1.18 303 3021
643 Excessive vomiting in pregnancy pregnancy complications Female 0.4656 1.05 0.918,1.2 215 2149 0.9817 1.0 0.849,1.18 148 1501
643.1 Hyperemesis gravidarum pregnancy complications Female 0.9204 1.01 0.856,1.19 153 1525 0.9817 1.0 0.849,1.18 148 1501
645 Late pregnancy and failed induction pregnancy complications Female 0.1524 1.04 0.984,1.11 1250 12450 0.191 1.04 0.981,1.1 1232 12268
646 Other complications of pregnancy NEC pregnancy complications Female 0.8337 1.0 0.962,1.05 2228 20847 0.9016 1.0 0.96,1.05 2190 20563
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.01 0.714 0.553,0.923 68 679 0.9078 1.01 0.891,1.14 274 2715
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.929 1.01 0.889,1.14 275 2748 0.9078 1.01 0.891,1.14 274 2715
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.4227 0.924 0.762,1.12 113 1129 0.4753 1.05 0.912,1.22 190 1889
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.4842 1.05 0.912,1.21 193 1922 0.4753 1.05 0.912,1.22 190 1889
650 Normal delivery pregnancy complications Female 0.02512 0.948 0.904,0.993 1922 18973 0.02692 0.948 0.904,0.994 1890 18723
651 Multiple gestation pregnancy complications Female 0.07079 1.11 0.992,1.24 346 3454 0.1253 1.09 0.976,1.22 338 3398
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.2523 1.03 0.979,1.08 1716 16521 0.3855 1.02 0.972,1.08 1684 16301
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.7551 1.01 0.955,1.07 1401 13649 0.9226 1.0 0.949,1.06 1379 13468
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.191 1.17 0.923,1.49 74 739 0.2851 1.14 0.896,1.45 72 725
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.7112 1.01 0.974,1.04 4306 29454 0.9661 1.0 0.969,1.03 4238 29051
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.06457 0.829 0.679,1.01 109 1080 0.06918 0.831 0.68,1.01 108 1066
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.7129 0.992 0.949,1.04 2265 18397 0.6295 0.989 0.947,1.03 2234 18166
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.5559 1.03 0.939,1.12 532 5316 0.5649 1.03 0.939,1.12 527 5243
665 Obstetrical/birth trauma pregnancy complications Female 0.257 0.983 0.954,1.01 5313 29472 0.2061 0.981 0.952,1.01 5224 29072
669 Complications of labor and delivery NEC pregnancy complications Female 0.2148 1.03 0.985,1.07 2552 21174 0.3342 1.02 0.979,1.06 2507 20909
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.08128 1.16 0.983,1.36 164 1628 0.07244 1.16 0.987,1.37 161 1606
674 Other complications of the puerperium NEC pregnancy complications Female 0.8337 1.01 0.894,1.15 262 2605 0.9057 1.01 0.888,1.14 259 2570
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.9057 1.02 0.769,1.34 63 624 0.8851 1.02 0.772,1.35 63 614
679 Complications of in utero procedures dermatologic Female 0.7943 0.963 0.726,1.28 53 530 0.7998 0.963 0.723,1.28 51 523
681 Superficial cellulitis and abscess dermatologic Both 0.01288 1.03 1.01,1.06 7200 72225 0.4064 1.04 0.951,1.13 559 5791
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.9572 0.998 0.915,1.09 563 5647 0.7379 0.985 0.902,1.08 541 5439
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.05754 1.09 0.997,1.2 520 5208 0.06761 1.09 0.994,1.2 501 5028
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.06026 1.03 0.999,1.06 5481 55014 0.09772 1.02 0.996,1.05 5227 52947
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.0631 1.03 0.999,1.06 5487 55074 0.1045 1.02 0.995,1.05 5234 53007
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.07586 1.03 0.997,1.05 5444 54643 0.1236 1.02 0.994,1.05 5192 52590
681.7 Cellulitis and abscess of trunk dermatologic Both 0.2113 1.06 0.97,1.15 597 5987 0.4064 1.04 0.951,1.13 559 5791
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.01175 1.07 1.02,1.14 1337 13427 0.6982 1.02 0.917,1.14 340 3507
686.1 Carbuncle and furuncle dermatologic Both 0.3614 1.02 0.977,1.07 2284 22925 0.3006 1.02 0.979,1.07 2202 22158
686.3 Pilonidal cyst dermatologic Both 0.2094 1.06 0.97,1.15 583 5837 0.3491 1.04 0.955,1.14 562 5718
686.4 Pyogenic granuloma dermatologic Both 0.3516 1.05 0.946,1.17 362 3615 0.6982 1.02 0.917,1.14 340 3507
687 Symptoms affecting skin dermatologic Both 0.1035 1.08 0.985,1.18 548 5508 0.6295 1.01 0.971,1.05 2756 27915
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.06026 1.04 0.998,1.09 2146 21470 0.04365 1.05 1.0,1.1 2029 20681
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.3828 1.06 0.935,1.19 283 2839 0.4581 1.05 0.926,1.19 269 2710
687.3 Changes in skin texture dermatologic Both 0.9078 1.01 0.828,1.24 106 1070 0.6998 1.04 0.843,1.29 92 1020
687.4 Disturbance of skin sensation dermatologic Both 0.7047 1.01 0.97,1.05 2884 28859 0.6295 1.01 0.971,1.05 2756 27915
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 5.248E-10 1.09 1.06,1.12 5747 57521 4.074E-4 1.06 1.02,1.09 4626 55417
690 Erythematosquamous dermatosis dermatologic Both 0.3516 0.899 0.718,1.12 71 710 0.3882 0.899 0.706,1.15 61 691
690.1 Seborrheic dermatitis dermatologic Both 0.7396 0.958 0.745,1.23 53 530 ,
691 Congenital anomalies of skin dermatologic Both 0.0537 1.2 0.997,1.45 120 1199 0.1563 1.16 0.946,1.41 105 1162
694 Dyschromia and Vitiligo dermatologic Both 0.02344 1.08 1.01,1.15 986 9854 0.4808 0.933 0.769,1.13 109 1129
694.1 Vitiligo dermatologic Both 0.3819 0.891 0.689,1.15 60 599 0.4436 0.903 0.696,1.17 58 579
694.2 Other dyschromia dermatologic Both 0.00182 1.12 1.04,1.21 782 7821 0.3532 1.04 0.956,1.13 564 7568
694.3 Vascular disorders of skin dermatologic Both 0.4699 0.933 0.773,1.13 117 1170 0.4808 0.933 0.769,1.13 109 1129
695 Erythematous conditions dermatologic Both 0.0263 1.05 1.01,1.09 2379 23813 0.4645 1.04 0.939,1.15 436 4502
695.1 Toxic erythema dermatologic Both 0.7328 1.04 0.846,1.27 109 1090 0.7379 1.04 0.843,1.27 105 1056
695.2 Bullous dermatoses dermatologic Both 0.09333 1.17 0.975,1.4 137 1365 0.02291 1.35 1.04,1.74 69 697
695.21 Dermatitis herpetiformis dermatologic Both 0.5248 1.09 0.832,1.44 57 569 0.2576 1.18 0.887,1.57 52 539
695.22 Pemphigus and pemphigoid dermatologic Both 0.0309 1.32 1.03,1.69 73 727 0.02291 1.35 1.04,1.74 69 697
695.3 Rosacea dermatologic Both 0.05012 1.13 1.0,1.27 309 3097 0.03631 1.14 1.01,1.3 275 2962
695.4 Lupus (localized and systemic) dermatologic Both 0.4457 1.04 0.941,1.15 411 4114 0.9441 0.996 0.89,1.11 323 3301
695.41 Cutaneous lupus erythematosus dermatologic Both 0.6516 1.04 0.877,1.23 130 1295 0.5521 1.05 0.886,1.26 125 1265
695.42 Systemic lupus erythematosus dermatologic Both 0.867 1.01 0.904,1.13 340 3407 0.9441 0.996 0.89,1.11 323 3301
695.7 Prurigo and Lichen dermatologic Both 0.6368 1.02 0.946,1.09 775 7760 0.859 0.993 0.921,1.07 725 7451
695.8 Other specified erythematous conditions dermatologic Both 0.8492 0.987 0.866,1.13 236 2359 0.4634 0.918 0.73,1.15 72 739
695.81 Erythema nodosum dermatologic Both 0.4236 0.913 0.731,1.14 76 760 0.4634 0.918 0.73,1.15 72 739
695.9 Unspecified erythematous condition dermatologic Both 0.3784 1.04 0.948,1.15 467 4672 0.4645 1.04 0.939,1.15 436 4502
696 Psoriasis and related disorders dermatologic Both 0.9183 0.998 0.955,1.04 2252 22509 0.5808 1.02 0.945,1.11 678 6834
696.4 Psoriasis dermatologic Both 0.9863 1.0 0.956,1.04 2198 21969 0.5808 1.02 0.945,1.11 678 6834
696.41 Psoriasis vulgaris dermatologic Both 0.9204 0.997 0.948,1.05 1680 16796 0.4667 0.981 0.931,1.03 1572 16164
696.42 Psoriatic arthropathy dermatologic Both 0.4207 1.03 0.955,1.12 706 7052 0.5808 1.02 0.945,1.11 678 6834
697 Sarcoidosis dermatologic Both 0.695 1.02 0.933,1.11 539 5373 0.4046 1.04 0.95,1.14 507 5196
698 Pruritus and related conditions dermatologic Both 0.2679 1.04 0.969,1.12 782 7814 0.3404 1.04 0.962,1.12 746 7548
700 Corns and callosities dermatologic Both 0.9311 1.01 0.894,1.13 291 2904 0.5728 1.04 0.916,1.17 269 2789
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 4.074E-9 1.1 1.06,1.13 4663 46650 0.2588 1.14 0.906,1.45 80 974
701.1 Keratoderma, acquired dermatologic Both 5.37E-4 1.47 1.18,1.83 87 870 7.079E-4 1.49 1.18,1.87 76 836
701.2 Scar conditions and fibrosis of skin dermatologic Both 1.738E-8 1.13 1.08,1.18 2348 23478 0.003631 1.08 1.02,1.13 1735 22700
701.3 Circumscribed scleroderma dermatologic Both 0.3034 0.874 0.676,1.13 61 610 0.2979 0.87 0.668,1.13 58 587
701.4 Keloid scar dermatologic Both 0.6637 1.03 0.896,1.19 216 2159 0.8531 0.985 0.843,1.15 180 2100
701.5 Abnormal granulation tissue dermatologic Both 0.5834 1.03 0.933,1.13 455 4568 0.859 1.01 0.911,1.12 403 4417
701.6 Acquired acanthosis nigricans dermatologic Both 0.08128 1.21 0.977,1.49 102 1019 0.2588 1.14 0.906,1.45 80 974
702 Degenerative skin conditions and other dermatoses dermatologic Both 3.162E-24 1.16 1.12,1.19 5459 54587 0.003715 1.06 1.02,1.11 2380 29632
702.1 Actinic keratosis dermatologic Both 2.512E-19 1.21 1.16,1.26 2585 25842 4.786E-5 1.11 1.05,1.16 1714 24817
702.2 Seborrheic keratosis dermatologic Both 3.802E-9 1.12 1.08,1.16 3078 30772 0.003715 1.06 1.02,1.11 2380 29632
703 Diseases of nail, NOS dermatologic Both 0.9311 0.995 0.89,1.11 354 3539 0.003311 1.11 1.03,1.18 927 9341
703.1 Ingrowing nail dermatologic Both 0.005623 1.1 1.03,1.17 966 9660 0.003311 1.11 1.03,1.18 927 9341
704 Diseases of hair and hair follicles dermatologic Both 0.001549 1.05 1.02,1.08 5267 52727 0.0871 0.804 0.627,1.03 61 744
704.1 Alopecia dermatologic Both 0.171 0.886 0.744,1.05 125 1269 0.1675 0.88 0.734,1.06 113 1239
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.3793 0.903 0.719,1.13 76 759 0.0871 0.804 0.627,1.03 61 744
705 Disorders of sweat glands dermatologic Both 0.2483 1.08 0.945,1.24 228 2287 0.929 0.996 0.913,1.09 556 5651
705.3 Hidradenitis dermatologic Both 0.1387 1.12 0.964,1.3 186 1868 0.125 1.13 0.968,1.31 182 1819
705.8 Hyperhidrosis dermatologic Both 0.6152 1.02 0.939,1.11 591 5919 0.929 0.996 0.913,1.09 556 5651
706 Diseases of sebaceous glands dermatologic Both 1.148E-4 1.05 1.02,1.07 8317 83195 1.549E-5 1.05 1.03,1.07 8335 84902
706.1 Acne dermatologic Both 0.1009 0.82 0.647,1.04 78 779 0.177 0.843 0.659,1.08 73 755
706.2 Sebaceous cyst dermatologic Both 9.772E-6 1.05 1.03,1.07 8787 87882 1.549E-5 1.05 1.03,1.07 8335 84902
707 Chronic ulcer of skin dermatologic Both 0.5521 1.01 0.968,1.06 1953 19654 0.8414 1.01 0.939,1.08 867 8682
707.1 Decubitus ulcer dermatologic Both 0.6839 1.01 0.947,1.09 909 9097 0.8414 1.01 0.939,1.08 867 8682
709 Diffuse diseases of connective tissue dermatologic Both 0.877 0.997 0.963,1.03 3432 34317 0.6592 1.01 0.969,1.05 2601 26145
709.2 Sicca syndrome dermatologic Both 0.6081 0.977 0.892,1.07 508 5073 0.4539 0.965 0.88,1.06 485 4902
709.3 Systemic sclerosis dermatologic Both 0.7464 0.974 0.833,1.14 176 1753 0.8375 0.983 0.837,1.16 166 1686
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.7161 1.05 0.818,1.34 65 649 0.9376 0.99 0.767,1.28 61 630
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.826 1.0 0.966,1.04 2714 27144 0.6592 1.01 0.969,1.05 2601 26145
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.3334 1.02 0.978,1.07 2094 20961 0.6561 1.01 0.965,1.06 1974 20190
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.6266 1.02 0.939,1.11 602 6034 0.3581 1.05 0.945,1.17 380 3858
710.1 Osteomyelitis musculoskeletal Both 0.456 1.03 0.947,1.13 556 5574 0.3581 1.05 0.945,1.17 380 3858
710.12 Chronic osteomyelitis musculoskeletal Both 0.4955 1.06 0.903,1.23 194 1947 0.1607 1.12 0.956,1.31 185 1878
710.19 Unspecified osteomyelitis musculoskeletal Both 0.5224 1.03 0.933,1.15 398 3997 0.3581 1.05 0.945,1.17 380 3858
711 Arthropathy associated with infections musculoskeletal Both 0.9863 1.0 0.906,1.11 421 4225 0.3954 1.05 0.937,1.18 317 3185
711.1 Pyogenic arthritis musculoskeletal Both 0.5794 1.03 0.923,1.15 328 3296 0.3954 1.05 0.937,1.18 317 3185
712 Infective connective tissue disorders musculoskeletal Both 0.2032 0.867 0.695,1.08 81 810 0.4121 0.909 0.724,1.14 76 770
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.4375 1.06 0.909,1.25 148 1499 0.2158 1.18 0.908,1.53 63 648
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.2636 1.16 0.895,1.5 65 669 0.2158 1.18 0.908,1.53 63 648
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.3707 1.01 0.984,1.04 4832 48320 0.2023 1.02 0.989,1.05 4113 42102
714.1 Rheumatoid arthritis musculoskeletal Both 0.1104 1.03 0.994,1.06 4372 43714 0.2023 1.02 0.989,1.05 4113 42102
715 Other inflammatory spondylopathies musculoskeletal Both 0.5754 1.01 0.964,1.07 1659 16588 0.9772 1.0 0.92,1.09 592 5967
715.1 Sacroiliitis NEC musculoskeletal Both 0.1871 0.877 0.721,1.07 113 1129 0.3802 0.914 0.747,1.12 107 1085
715.2 Ankylosing spondylitis musculoskeletal Both 0.8995 0.995 0.916,1.08 618 6177 0.9772 1.0 0.92,1.09 592 5967
716 Other arthropathies musculoskeletal Both 0.01122 1.01 1.0,1.03 37478 265375 0.0138 1.01 1.0,1.03 34225 253125
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.3819 1.02 0.981,1.05 3505 35090 0.5728 1.01 0.975,1.05 3336 33646
716.2 Unspecified monoarthritis musculoskeletal Both 0.2123 1.01 0.994,1.03 15522 155339 0.1841 1.01 0.995,1.03 14846 149246
716.9 Arthropathy NOS musculoskeletal Both 0.007586 1.02 1.0,1.03 35944 262308 0.0138 1.01 1.0,1.03 34225 253125
717 Polymyalgia Rheumatica musculoskeletal Both 0.7278 0.989 0.93,1.05 1145 11480 0.8511 0.994 0.933,1.06 1088 10860
720 Spinal stenosis musculoskeletal Both 0.7178 1.01 0.973,1.04 3705 37091 0.8017 1.0 0.97,1.04 3536 35533
721 Spondylosis and allied disorders musculoskeletal Both 0.1245 1.02 0.995,1.04 7832 78318 0.4276 1.05 0.935,1.17 342 3378
721.1 Spondylosis without myelopathy musculoskeletal Both 0.5164 1.01 0.981,1.04 5045 50451 0.4842 1.01 0.981,1.04 4834 48443
721.2 Spondylosis with myelopathy musculoskeletal Both 0.1409 1.12 0.963,1.31 189 1899 0.1644 1.12 0.956,1.3 185 1830
721.8 Other allied disorders of spine musculoskeletal Both 0.4102 1.05 0.938,1.17 352 3519 0.4276 1.05 0.935,1.17 342 3378
722 Intervertebral disc disorders musculoskeletal Both 0.5875 0.994 0.973,1.02 8978 89848 0.1072 0.974 0.944,1.01 4240 42632
722.1 Displacement of intervertebral disc musculoskeletal Both 0.3802 0.961 0.878,1.05 512 5116 0.4406 0.965 0.881,1.06 499 4938
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.05495 1.04 0.999,1.08 2831 28328 0.0263 1.05 1.01,1.09 2712 27282
722.8 Postlaminectomy syndrome musculoskeletal Both 0.02344 1.34 1.04,1.74 67 669 0.02818 1.33 1.03,1.72 66 654
722.9 Other and unspecified disc disorder musculoskeletal Both 0.1435 0.977 0.947,1.01 4407 44127 0.1072 0.974 0.944,1.01 4240 42632
723 Other disorders of cervical region musculoskeletal Both 0.4276 0.965 0.882,1.05 517 5173 0.975 0.997 0.824,1.21 105 1027
723.1 Torticollis musculoskeletal Both 0.6668 0.959 0.793,1.16 107 1068 0.975 0.997 0.824,1.21 105 1027
724 Other and unspecified disorders of back musculoskeletal Both 0.8414 1.0 0.96,1.05 2052 20514 0.869 1.0 0.954,1.06 1564 15560
724.1 Disorders of sacrum musculoskeletal Both 0.4571 1.04 0.939,1.15 403 4024 0.7244 1.02 0.918,1.13 381 3883
724.2 Disorders of coccyx musculoskeletal Both 0.5224 1.03 0.934,1.14 406 4054 0.7798 1.01 0.915,1.13 384 3917
724.8 Other symptoms referable to back musculoskeletal Both 0.4989 0.916 0.709,1.18 63 630 0.5023 0.915 0.707,1.19 63 604
724.9 Other unspecified back disorders musculoskeletal Both 0.9661 0.999 0.949,1.05 1614 16139 0.869 1.0 0.954,1.06 1564 15560
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.004074 1.03 1.01,1.04 14663 146691 0.2009 1.05 0.975,1.13 819 8271
726.1 Enthesopathy musculoskeletal Both 3.467E-4 1.04 1.02,1.06 9589 95900 2.63E-4 1.04 1.02,1.06 9203 92341
726.2 Synoviopathy musculoskeletal Both 0.6324 1.03 0.917,1.15 334 3336 0.7816 1.02 0.904,1.14 317 3243
726.3 Bursitis musculoskeletal Both 0.1349 1.06 0.983,1.13 854 8573 0.2009 1.05 0.975,1.13 819 8271
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.9397 1.0 0.977,1.03 7331 73332 0.3715 1.08 0.909,1.29 137 1379
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.5248 1.01 0.974,1.05 2737 27406 0.5623 1.01 0.972,1.05 2606 26469
727.2 Bursitis disorders musculoskeletal Both 1.0 1.0 0.82,1.22 103 1029 0.9247 1.01 0.827,1.23 102 991
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.2307 0.978 0.942,1.01 3109 31085 0.2377 0.978 0.941,1.02 2999 30050
727.5 Rupture of synovium musculoskeletal Both 0.07762 1.08 0.991,1.18 586 5854 0.0912 1.08 0.988,1.17 565 5629
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.5333 1.04 0.928,1.16 353 3527 0.3475 1.06 0.943,1.18 331 3387
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.4188 1.07 0.903,1.28 143 1429 0.3715 1.08 0.909,1.29 137 1379
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.03311 1.04 1.0,1.07 3677 36788 0.1567 1.03 0.99,1.06 3286 33217
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.8851 1.01 0.911,1.11 412 4115 1.0 1.0 0.902,1.11 399 4000
728.7 Fasciitis musculoskeletal Both 0.03236 1.04 1.0,1.07 3803 38045 0.1567 1.03 0.99,1.06 3286 33217
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.0257 1.04 1.0,1.08 3477 34788 0.1567 1.03 0.99,1.06 3286 33217
729 Other disorders of soft tissues musculoskeletal Both 0.3266 1.01 0.987,1.04 6014 60309 0.05012 0.816 0.665,1.0 98 976
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.1963 1.04 0.979,1.11 1005 10063 0.2576 1.04 0.973,1.11 968 9761
729.3 Panniculitis musculoskeletal Both 0.07762 0.835 0.683,1.02 101 1009 0.05012 0.816 0.665,1.0 98 976
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.0955 1.11 0.982,1.26 276 2758 0.1578 1.1 0.965,1.25 247 2518
731.1 Osteitis deformans [Paget's disease of bone] musculoskeletal Both 0.1014 1.11 0.98,1.26 261 2609 0.1578 1.1 0.965,1.25 247 2518
732 Osteochondropathies musculoskeletal Both 0.07244 0.914 0.829,1.01 467 4679 0.139 0.812 0.616,1.07 57 561
732.1 Juvenile osteochondrosis musculoskeletal Both 0.1923 0.909 0.788,1.05 207 2068 0.3133 0.927 0.801,1.07 200 2007
732.7 Osteochondritis dissecans musculoskeletal Both 0.1309 0.809 0.615,1.06 57 570 0.139 0.812 0.616,1.07 57 561
733 Other disorders of bone and cartilage musculoskeletal Both 0.526 1.02 0.968,1.07 1777 17814 0.4345 1.08 0.891,1.31 116 1161
733.2 Cyst of bone musculoskeletal Both 0.9376 1.0 0.895,1.13 311 3115 0.9268 1.01 0.893,1.13 295 3000
733.4 Aseptic necrosis of bone musculoskeletal Both 0.2037 1.06 0.969,1.16 540 5393 0.9397 0.996 0.904,1.1 450 5182
733.6 Costochondritis musculoskeletal Both 0.3266 1.09 0.913,1.31 128 1276 0.1574 1.14 0.95,1.37 125 1229
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.9333 1.0 0.945,1.06 1231 12313 0.8511 1.01 0.947,1.07 1193 11896
733.9 Chondromalacia musculoskeletal Both 0.4797 1.07 0.886,1.29 121 1206 0.4345 1.08 0.891,1.31 116 1161
735 Acquired foot deformities musculoskeletal Both 0.4753 1.01 0.987,1.03 9603 96090 0.4853 1.01 0.983,1.04 6351 64147
735.1 Flat foot musculoskeletal Both 0.4603 1.06 0.912,1.23 189 1910 0.2897 1.09 0.933,1.26 181 1833
735.2 Acquired toe deformities musculoskeletal Both 0.6039 1.01 0.979,1.04 5070 50712 0.2649 1.03 0.977,1.09 1484 14974
735.21 Hammer toe (acquired) musculoskeletal Both 0.9931 1.0 0.954,1.05 1929 19324 0.9016 0.997 0.95,1.05 1838 18578
735.23 Hallux rigidus musculoskeletal Both 0.263 1.03 0.978,1.09 1555 15527 0.2649 1.03 0.977,1.09 1484 14974
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.5188 1.01 0.983,1.03 6643 66463 0.4853 1.01 0.983,1.04 6351 64147
736 Other acquired deformities of limbs musculoskeletal Both 0.8954 0.997 0.947,1.05 1627 16282 0.25 1.08 0.947,1.23 237 2378
736.2 Acquired deformities of finger musculoskeletal Both 0.177 1.09 0.961,1.24 248 2476 0.25 1.08 0.947,1.23 237 2378
737 Curvature of spine musculoskeletal Both 0.5546 1.02 0.959,1.08 1128 11300 0.3491 1.03 0.967,1.1 1003 10225
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.5715 1.02 0.957,1.08 1061 10632 0.3491 1.03 0.967,1.1 1003 10225
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.389 1.02 0.974,1.07 1904 19058 0.04786 1.06 1.0,1.12 1447 14544
738.4 Acquired spondylolisthesis musculoskeletal Both 0.06918 1.05 0.996,1.11 1513 15147 0.04786 1.06 1.0,1.12 1447 14544
739 Contracture of joint musculoskeletal Both 0.5176 1.03 0.94,1.13 488 4884 0.4055 1.04 0.947,1.14 471 4717
740 Osteoarthrosis musculoskeletal Both 0.07244 1.01 0.999,1.02 27707 231603 0.1496 1.01 0.995,1.03 11606 117760
740.1 Osteoarthritis; localized musculoskeletal Both 0.2333 1.01 0.994,1.03 17412 169419 0.7798 1.02 0.908,1.14 331 3374
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.5808 1.01 0.985,1.03 8974 89750 0.4853 1.01 0.986,1.03 8573 85918
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.9311 1.0 0.9,1.12 348 3474 0.7798 1.02 0.908,1.14 331 3374
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.04898 1.09 1.0,1.18 598 5969 0.1183 1.07 0.982,1.17 555 5687
740.9 Osteoarthrosis NOS musculoskeletal Both 0.04677 1.02 1.0,1.04 12270 122792 0.1496 1.01 0.995,1.03 11606 117760
741 Symptoms and disorders of the joints musculoskeletal Both 0.9484 0.999 0.965,1.03 3563 35648 0.04169 1.36 1.01,1.82 54 524
741.1 Ankylosis of joint musculoskeletal Both 0.6761 1.04 0.852,1.28 102 1019 0.8492 1.02 0.829,1.26 99 982
741.2 Stiffness of joint musculoskeletal Both 0.1057 0.935 0.862,1.01 614 6146 0.1033 0.933 0.858,1.01 585 5926
741.3 Difficulty in walking musculoskeletal Both 0.3199 1.09 0.921,1.28 154 1540 0.3837 1.08 0.909,1.28 145 1479
741.4 Joint effusions musculoskeletal Both 0.2951 0.971 0.919,1.03 1418 14197 0.2477 0.967 0.915,1.02 1350 13657
741.5 Hemarthrosis musculoskeletal Both 0.4102 0.92 0.755,1.12 110 1100 0.4898 0.932 0.762,1.14 105 1052
741.6 Villonodular synovitis musculoskeletal Both 0.04677 1.35 1.0,1.81 54 535 0.04169 1.36 1.01,1.82 54 524
742 Derangement of joint, non-traumatic musculoskeletal Both 0.8892 1.0 0.965,1.04 2843 28441 0.3945 1.02 0.974,1.07 1925 19389
742.1 Loose body in joint musculoskeletal Both 0.1832 0.926 0.826,1.04 333 3337 0.13 0.915 0.815,1.03 322 3231
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.4083 0.913 0.736,1.13 95 960 0.4046 0.913 0.736,1.13 95 944
742.8 Articular cartilage disorder musculoskeletal Both 0.2333 0.946 0.865,1.04 500 4996 0.2014 0.942 0.859,1.03 479 4840
742.9 Other derangement of joint musculoskeletal Both 0.246 1.03 0.981,1.08 1993 19926 0.3945 1.02 0.974,1.07 1925 19389
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.2317 1.01 0.991,1.04 7563 75729 0.3532 0.966 0.897,1.04 772 7875
743.1 Osteoporosis musculoskeletal Both 0.1189 1.02 0.995,1.05 6400 64107 0.7112 0.983 0.895,1.08 494 5040
743.11 Osteoporosis NOS musculoskeletal Both 0.3673 1.01 0.985,1.04 5549 55604 0.302 1.02 0.987,1.04 5229 53334
743.13 Other specified osteoporosis musculoskeletal Both 0.9886 1.0 0.915,1.09 529 5283 0.7112 0.983 0.895,1.08 494 5040
743.2 Pathologic fracture musculoskeletal Both 0.6637 1.02 0.932,1.12 516 5179 0.873 1.01 0.918,1.11 489 4985
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.4764 0.974 0.907,1.05 815 8144 0.3532 0.966 0.897,1.04 772 7875
745 Pain in joint musculoskeletal Both 0.1132 1.02 0.996,1.04 7975 79789 0.1069 1.02 0.996,1.04 7679 77024
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.3112 0.98 0.942,1.02 2802 28058 0.9727 0.997 0.847,1.17 163 1628
747.1 Cardiac congenital anomalies congenital anomalies Both 0.2307 0.976 0.937,1.02 2628 26323 0.06918 0.955 0.908,1.0 1720 17295
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.3767 0.962 0.883,1.05 584 5838 0.5 0.971 0.89,1.06 562 5633
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.547 0.96 0.841,1.1 235 2358 0.5794 0.963 0.842,1.1 228 2287
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.09772 0.96 0.914,1.01 1816 18200 0.06918 0.955 0.908,1.0 1720 17295
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.9795 1.0 0.853,1.18 167 1680 0.9727 0.997 0.847,1.17 163 1628
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.8375 1.03 0.778,1.36 51 510 ,
749 Congenital anomalies of face and neck congenital anomalies Both 0.7328 0.98 0.872,1.1 303 3029 0.9226 0.994 0.881,1.12 284 2923
750 Digestive congenital anomalies congenital anomalies Both 0.01047 1.11 1.02,1.2 686 6870 0.06607 1.2 0.987,1.47 104 1139
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.06607 1.11 0.993,1.25 327 3263 0.7311 0.974 0.836,1.13 178 1821
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.9977 1.0 0.863,1.16 191 1909 0.7311 0.974 0.836,1.13 178 1821
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.1629 1.08 0.969,1.21 356 3574 0.06607 1.2 0.987,1.47 104 1139
750.21 Congenital anomalies of intestine congenital anomalies Both 0.871 0.989 0.861,1.13 225 2256 0.912 0.992 0.864,1.14 222 2186
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.008511 1.29 1.07,1.56 117 1179 0.06607 1.2 0.987,1.47 104 1139
751 Genitourinary congenital anomalies congenital anomalies Both 0.631 1.01 0.961,1.07 1527 15286 0.2254 0.93 0.827,1.05 318 3230
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.8222 1.01 0.933,1.09 694 6932 0.9268 1.01 0.876,1.16 216 2140
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.7534 1.02 0.922,1.12 455 4546 0.6808 1.02 0.926,1.13 443 4445
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.9886 0.999 0.87,1.15 222 2217 0.9268 1.01 0.876,1.16 216 2140
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.7889 1.01 0.94,1.09 836 8385 0.2254 0.93 0.827,1.05 318 3230
751.21 Cystic kidney disease congenital anomalies Both 0.0955 1.09 0.985,1.21 424 4246 0.2667 1.06 0.955,1.18 383 4089
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.3882 0.951 0.847,1.07 333 3346 0.2254 0.93 0.827,1.05 318 3230
752 Nervous system congenital anomalies congenital anomalies Both 0.975 1.0 0.896,1.12 328 3307 0.4786 1.09 0.861,1.38 76 754
752.1 Neural tube defects congenital anomalies Both 0.6776 1.03 0.905,1.17 253 2557 0.1986 1.1 0.952,1.27 203 2046
752.11 Spina bifida congenital anomalies Both 0.2118 1.09 0.95,1.26 208 2108 0.1986 1.1 0.952,1.27 203 2046
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.6012 1.06 0.843,1.34 78 780 0.4786 1.09 0.861,1.38 76 754
753 Congenital anomalies of the eye congenital anomalies Both 0.01202 0.794 0.663,0.951 127 1270 0.1629 0.845 0.666,1.07 74 737
753.1 Congenital cataract and lens anomalies congenital anomalies Both 0.1986 0.858 0.679,1.08 76 760 0.1629 0.845 0.666,1.07 74 737
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.4436 0.928 0.768,1.12 109 1099 0.5929 0.948 0.781,1.15 104 1061
755 Congenital anomalies of limbs congenital anomalies Both 0.6561 1.02 0.926,1.13 425 4276 0.5598 0.94 0.762,1.16 104 1037
755.1 Congenital deformities of feet congenital anomalies Both 0.4688 1.05 0.916,1.21 208 2086 0.7047 1.03 0.89,1.19 194 2019
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.8433 0.984 0.836,1.16 160 1620 0.5598 0.94 0.762,1.16 104 1037
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.5998 0.946 0.77,1.16 106 1070 0.5598 0.94 0.762,1.16 104 1037
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.3926 1.04 0.954,1.13 587 5872 0.984 0.999 0.903,1.1 418 4210
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.5728 1.07 0.853,1.33 81 810 0.3548 1.12 0.885,1.41 75 793
756.5 Congenital osteodystrophies congenital anomalies Both 0.8472 0.99 0.898,1.09 435 4356 0.984 0.999 0.903,1.1 418 4210
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.5623 1.05 0.888,1.24 148 1708 0.5321 0.922 0.714,1.19 55 802
758.1 Chromosomal anomalies congenital anomalies Both 0.7063 0.953 0.743,1.22 60 830 0.5321 0.922 0.714,1.19 55 802
759 Other and unspecified congenital anomalies congenital anomalies Both 0.2198 1.09 0.949,1.26 216 2159 0.9528 1.01 0.815,1.24 94 930
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.9376 1.01 0.818,1.24 96 959 0.9528 1.01 0.815,1.24 94 930
760 Back pain symptoms Both 0.2193 1.01 0.993,1.03 11126 111353 0.4315 1.01 0.988,1.03 10715 107406
761 Cervicalgia symptoms Both 0.542 1.02 0.967,1.07 1791 17901 0.52 1.02 0.967,1.07 1725 17327
764 Sciatica symptoms Both 0.597 0.989 0.948,1.03 2372 23732 0.5395 0.987 0.945,1.03 2287 22896
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.3251 0.971 0.915,1.03 1172 11738 0.2173 0.963 0.906,1.02 1121 11319
770 Myalgia and myositis unspecified symptoms Both 0.1832 1.06 0.974,1.15 631 6311 0.1799 1.06 0.974,1.15 603 6077
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.5546 0.979 0.913,1.05 870 8687 0.5675 1.01 0.978,1.04 4428 44519
771.1 Swelling of limb symptoms Both 0.6383 1.01 0.977,1.04 4617 46330 0.5675 1.01 0.978,1.04 4428 44519
772 Symptoms of the muscles symptoms Both 0.1455 1.06 0.98,1.15 659 6581 0.2301 1.05 0.968,1.14 626 6333
773 Pain in limb symptoms Both 0.8954 0.998 0.973,1.02 6209 62203 0.9484 1.0 0.975,1.03 5962 59987
780 Hypothermia/Chills symptoms Both 0.7603 0.976 0.836,1.14 171 1719 0.9727 0.997 0.849,1.17 160 1646
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.7925 1.01 0.96,1.06 1870 18715 0.9036 0.997 0.95,1.05 1785 18033
782.3 Edema symptoms Both 0.7482 0.992 0.943,1.04 1642 16450 0.9141 0.997 0.947,1.05 1563 15789
782.6 Pallor and flushing symptoms Both 0.9397 0.994 0.85,1.16 175 1748 0.8166 1.02 0.868,1.2 167 1695
783 Fever of unknown origin symptoms Both 0.3459 1.02 0.983,1.05 3911 39105 0.4603 1.01 0.979,1.05 3716 37655
785 Abdominal pain symptoms Both 0.1076 1.01 0.998,1.02 40080 301686 0.08913 1.01 0.999,1.02 38557 291645
788 Syncope and collapse symptoms Both 0.3837 1.01 0.988,1.03 9069 90813 0.3846 1.01 0.988,1.03 8686 87127
789 Nausea and vomiting symptoms Both 0.4083 1.01 0.989,1.03 11577 115807 0.3673 1.01 0.989,1.03 11079 111580
790 Nonspecific findings on examination of blood symptoms Both 0.8356 0.982 0.83,1.16 150 1500 0.1914 1.02 0.991,1.05 5997 60716
790.1 Elevated sedimentation rate symptoms Both 0.5333 0.93 0.74,1.17 84 840 0.5333 0.929 0.738,1.17 82 809
790.6 Other abnormal blood chemistry symptoms Both 0.2018 1.02 0.991,1.04 6357 63635 0.1914 1.02 0.991,1.05 5997 60716
791 Gangrene symptoms Both 0.06457 0.92 0.843,1.0 549 5501 0.07244 0.921 0.841,1.01 523 5277
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.1127 1.18 0.961,1.46 98 966 0.0537 1.23 0.996,1.53 92 933
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.7499 0.971 0.809,1.17 134 1340 0.5675 0.974 0.89,1.07 536 5413
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.5408 0.973 0.891,1.06 565 5647 0.5675 0.974 0.89,1.07 536 5413
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.871 0.984 0.814,1.19 120 1198 0.877 0.985 0.815,1.19 120 1173
797 Shock symptoms Both 0.5212 0.948 0.806,1.12 156 1559 0.6053 0.948 0.775,1.16 100 975
797.1 Cardiogenic shock symptoms Both 0.3258 0.905 0.742,1.1 102 1020 0.6053 0.948 0.775,1.16 100 975
798 Malaise and fatigue symptoms Both 0.7798 1.01 0.97,1.04 3408 34103 0.798 0.989 0.907,1.08 571 5730
798.1 Chronic fatigue syndrome symptoms Both 0.7534 0.987 0.907,1.07 591 5913 0.798 0.989 0.907,1.08 571 5730
800 Fracture of lower limb injuries & poisonings Both 0.5834 1.01 0.982,1.03 7035 70329 0.9141 0.996 0.923,1.07 732 7345
800.1 Fracture of neck of femur injuries & poisonings Both 0.4786 1.02 0.97,1.07 1815 18152 0.6699 1.01 0.962,1.06 1743 17365
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.08511 0.87 0.742,1.02 170 1693 0.1005 0.873 0.742,1.03 163 1616
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.9354 1.0 0.958,1.05 2158 21577 0.9727 0.999 0.955,1.05 2091 20902
800.4 Fracture of patella injuries & poisonings Both 0.9419 0.997 0.926,1.07 766 7661 0.9141 0.996 0.923,1.07 732 7345
801 Fracture of ankle and foot injuries & poisonings Both 0.271 1.03 0.981,1.07 2205 22041 0.01778 1.06 1.01,1.11 1775 17762
801.1 Fracture of foot injuries & poisonings Both 0.02754 1.06 1.01,1.11 1835 18346 0.01778 1.06 1.01,1.11 1775 17762
802 Fracture of pelvis injuries & poisonings Both 0.7211 1.01 0.939,1.1 718 7185 0.6637 1.02 0.941,1.1 692 6915
803 Fracture of upper limb injuries & poisonings Both 0.235 1.01 0.991,1.04 8288 82880 0.1884 1.04 0.982,1.09 1466 14674
803.1 Fracture of humerus injuries & poisonings Both 0.6637 0.989 0.94,1.04 1691 16883 0.8414 0.995 0.945,1.05 1625 16248
803.2 Fracture of radius and ulna injuries & poisonings Both 0.2173 1.02 0.99,1.05 5215 52171 0.3622 1.01 0.985,1.04 5047 50359
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.16 1.04 0.985,1.1 1518 15186 0.1884 1.04 0.982,1.09 1466 14674
804 Fracture of hand or wrist injuries & poisonings Both 0.4808 0.987 0.953,1.02 3339 33384 0.2673 0.98 0.945,1.02 3224 32310
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.2366 1.03 0.978,1.09 1358 13565 0.2594 1.03 0.976,1.09 1312 13065
807 Fracture of ribs injuries & poisonings Both 0.6683 0.984 0.913,1.06 776 7752 0.7211 0.986 0.914,1.06 749 7462
809 Fracture of unspecified bones injuries & poisonings Both 0.507 1.02 0.963,1.08 1300 12998 0.3614 1.03 0.969,1.09 1253 12539
817 Concussion injuries & poisonings Both 0.1135 1.11 0.975,1.27 243 2428 0.06918 1.13 0.991,1.29 240 2334
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.9506 0.997 0.911,1.09 522 5213 0.9616 1.0 0.914,1.1 505 4991
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.6471 1.01 0.971,1.05 2957 29596 0.7516 1.01 0.968,1.05 2864 28674
823 Torus fracture injuries & poisonings Both 0.7047 1.01 0.96,1.06 1673 16710 0.6982 1.01 0.96,1.06 1624 16208
830 Dislocation injuries & poisonings Both 0.07244 1.04 0.996,1.09 2088 20872 0.0912 1.04 0.994,1.09 2015 20234
835 Internal derangement of knee injuries & poisonings Both 0.2183 1.01 0.994,1.03 15221 152247 0.2748 1.01 0.992,1.03 14650 147201
836 Traumatic arthropathy injuries & poisonings Both 0.0871 1.08 0.988,1.18 526 5267 0.05623 1.09 0.998,1.2 509 5075
840 Sprains and strains injuries & poisonings Both 0.2518 1.06 0.961,1.16 470 4697 0.2104 1.06 0.965,1.17 452 4531
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.05754 1.03 0.999,1.06 5259 52626 0.2153 1.02 0.989,1.05 4955 50711
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.007079 1.25 1.06,1.47 157 1567 0.09333 1.16 0.975,1.37 136 1512
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.9162 0.995 0.907,1.09 501 5010 0.861 0.992 0.901,1.09 466 4808
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.4966 0.983 0.937,1.03 1826 18238 0.3819 0.978 0.93,1.03 1722 17455
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.5458 1.02 0.961,1.08 1241 12418 0.8072 1.01 0.949,1.07 1182 11901
858 Complication of internal orthopedic device injuries & poisonings Both 0.2661 0.979 0.944,1.02 3158 31607 0.4325 0.985 0.949,1.02 3014 30372
859 Complication due to other implant and internal device injuries & poisonings Both 0.7311 1.01 0.971,1.04 3259 32599 0.8054 1.0 0.968,1.04 3105 31361
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.7762 0.995 0.961,1.03 3502 35062 0.6699 0.945 0.73,1.22 66 664
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.9683 0.997 0.88,1.13 272 2713 0.984 1.0 0.882,1.14 265 2619
870.2 Open wound of ear injuries & poisonings Both 0.5546 1.05 0.903,1.21 196 1949 0.4721 1.06 0.911,1.22 193 1879
870.3 Other open wound of head and face injuries & poisonings Both 0.3724 0.983 0.946,1.02 2904 29085 0.6281 0.99 0.953,1.03 2795 28007
870.4 Open wound of nose and sinus injuries & poisonings Both 0.3162 1.07 0.936,1.23 220 2199 0.3499 1.07 0.931,1.22 212 2105
870.6 Open wound of neck injuries & poisonings Both 0.597 0.934 0.724,1.2 68 678 0.6699 0.945 0.73,1.22 66 664
871 Open wounds of extremities injuries & poisonings Both 0.02884 0.965 0.934,0.996 4063 40648 0.0912 0.869 0.738,1.02 170 1729
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.1618 1.21 0.925,1.59 53 530 0.1387 1.24 0.934,1.64 53 510
871.2 Open wound of finger(s) injuries & poisonings Both 0.5943 1.06 0.858,1.31 91 900 0.5023 1.07 0.87,1.33 89 866
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.1191 0.882 0.753,1.03 178 1785 0.0912 0.869 0.738,1.02 170 1729
872 Traumatic amputation injuries & poisonings Both 0.6607 0.979 0.89,1.08 475 4742 0.7413 0.984 0.892,1.08 450 4557
873 Broken tooth injuries & poisonings Both 0.7112 0.975 0.855,1.11 229 2289 0.5834 0.963 0.843,1.1 224 2210
874 Complication of amputation stump injuries & poisonings Both 0.4169 1.07 0.909,1.26 169 1710 0.4966 1.06 0.898,1.25 162 1666
905 Late effects of musculoskeletal and connective tissue injuries injuries & poisonings Both 0.3819 0.928 0.785,1.1 157 1567 0.309 0.917 0.775,1.08 155 1517
907 Injuries to the nervous system injuries & poisonings Both 0.6855 0.988 0.934,1.05 1314 13140 0.7228 0.99 0.934,1.05 1266 12718
915 Superficial injury without mention of infection injuries & poisonings Both 0.2576 1.02 0.987,1.05 4260 42663 0.2606 1.02 0.986,1.05 4085 41042
916 Contusion injuries & poisonings Both 0.1069 0.956 0.906,1.01 1450 14506 0.0955 0.954 0.902,1.01 1388 13980
930 Allergic reaction to food injuries & poisonings Both 0.9036 1.01 0.867,1.18 179 1807 0.7709 1.02 0.877,1.19 174 1754
938 Dermatitis due to solar radiation injuries & poisonings Both 7.762E-5 1.23 1.11,1.37 389 3899 0.02754 1.19 1.02,1.39 166 2421
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 4.677E-4 1.26 1.11,1.43 252 2530 0.02754 1.19 1.02,1.39 166 2421
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.1626 0.91 0.797,1.04 225 2249 0.1803 0.909 0.79,1.05 203 2159
942 Infusion and transfusion reaction injuries & poisonings Both 0.2897 0.894 0.727,1.1 104 1038 0.3041 0.895 0.723,1.11 97 1001
946 Anaphylactic shock NOS injuries & poisonings Both 0.3319 1.04 0.956,1.14 550 5509 0.2466 1.05 0.964,1.15 535 5314
947 Urticaria injuries & poisonings Both 0.1954 1.07 0.964,1.19 371 3707 0.1726 1.08 0.967,1.2 358 3582
949 Allergies, other injuries & poisonings Both 0.08913 1.1 0.986,1.22 397 3989 0.07244 1.1 0.991,1.23 378 3877
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.09772 1.09 0.985,1.2 423 4224 0.0871 1.09 0.987,1.21 405 4068
957 Injury to other and unspecified nerves injuries & poisonings Both 0.7534 1.02 0.9,1.16 269 2698 0.4831 1.05 0.921,1.19 256 2580
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.6471 0.979 0.893,1.07 491 4926 0.2377 0.874 0.699,1.09 71 718
958.1 Postoperative shock injuries & poisonings Both 0.5309 0.915 0.693,1.21 55 555 0.3311 0.868 0.653,1.15 53 533
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.3573 0.901 0.723,1.12 74 740 0.2377 0.874 0.699,1.09 71 718
960 Poisoning by antibiotics injuries & poisonings Both 0.4742 1.01 0.99,1.02 18100 181147 0.6166 0.996 0.979,1.01 15056 153257
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.9354 0.999 0.983,1.02 15846 158623 0.6166 0.996 0.979,1.01 15056 153257
961 Poisoning by other anti-infectives injuries & poisonings Both 0.5346 0.969 0.878,1.07 420 4195 0.5943 1.02 0.95,1.09 829 8418
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.4467 1.03 0.958,1.1 869 8703 0.5943 1.02 0.95,1.09 829 8418
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.3133 1.06 0.95,1.17 371 3707 0.4236 1.05 0.937,1.17 343 3508
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.2286 1.07 0.959,1.19 364 3638 0.4236 1.05 0.937,1.17 343 3508
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.5861 0.963 0.84,1.1 223 2228 0.4102 0.943 0.821,1.08 213 2172
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.9705 0.998 0.879,1.13 282 2830 0.3945 1.06 0.929,1.2 264 2670
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.52 1.04 0.918,1.18 276 2770 0.3945 1.06 0.929,1.2 264 2670
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.3899 0.988 0.963,1.01 6082 60875 0.929 1.0 0.905,1.12 390 3930
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.1236 1.05 0.987,1.11 1144 11447 0.1641 1.04 0.982,1.11 1082 11056
965.2 Antirheumatics causing adverse effects in therapeutic use injuries & poisonings Both 0.9183 1.0 0.916,1.1 476 4767 0.8492 1.01 0.919,1.11 463 4656
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.8356 1.01 0.912,1.12 403 4045 0.929 1.0 0.905,1.12 390 3930
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.2553 0.948 0.866,1.04 512 5123 0.4797 0.967 0.881,1.06 487 4967
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.9795 1.0 0.92,1.09 583 5843 0.8954 1.01 0.923,1.1 558 5634
969 Poisoning by psychotropic agents injuries & poisonings Both 0.1291 0.965 0.921,1.01 1950 19519 0.1455 0.965 0.921,1.01 1887 19031
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.778 0.979 0.841,1.14 190 1908 0.7586 0.976 0.839,1.14 187 1859
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.4457 0.953 0.842,1.08 271 2717 0.7096 1.04 0.834,1.31 80 833
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.9204 1.01 0.813,1.26 84 849 0.7096 1.04 0.834,1.31 80 833
973 Poisoning by agents primarily affecting the gastrointestinal system injuries & poisonings Both 0.1986 1.14 0.934,1.39 108 1080 0.2218 1.13 0.927,1.39 105 1048
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.9141 0.989 0.812,1.21 101 1018 0.9954 1.0 0.818,1.22 97 971
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.09772 1.24 0.961,1.6 64 640 0.1059 1.24 0.956,1.6 63 620
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.9057 1.02 0.779,1.33 58 580 0.9683 1.01 0.762,1.33 54 560
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.05248 1.14 0.999,1.31 234 2337 0.03715 1.16 1.01,1.33 224 2258
979 Adverse drug events and drug allergies injuries & poisonings Both 0.5212 1.03 0.949,1.11 698 6966 0.4603 1.03 0.952,1.12 676 6763
981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents injuries & poisonings Both 0.9661 1.0 0.866,1.16 200 1999 0.9594 0.996 0.858,1.16 195 1943
986 Toxic effect of carbon monoxide injuries & poisonings Both 0.867 1.02 0.782,1.34 62 620 0.9204 1.01 0.773,1.33 61 601
987 Toxic effect of other gases, fumes, or vapors injuries & poisonings Both 0.5675 1.06 0.865,1.3 105 1049 0.4645 1.08 0.878,1.33 100 1013
988 Toxic effect of noxious substances eaten as food injuries & poisonings Both 0.3192 0.907 0.748,1.1 111 1128 0.4227 0.923 0.759,1.12 108 1090
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.7962 1.03 0.824,1.29 89 890 0.7063 1.05 0.831,1.31 84 857
990 Effects radiation NOS injuries & poisonings Both 0.6761 1.01 0.971,1.05 3113 31140 0.7691 0.994 0.957,1.03 2890 29801
994 Sepsis and SIRS injuries & poisonings Both 0.9397 0.999 0.962,1.04 3028 30268 0.8551 0.996 0.959,1.04 2861 29032
994.2 Sepsis injuries & poisonings Both 0.9397 0.999 0.962,1.04 3028 30268 0.8551 0.996 0.959,1.04 2861 29032
1000 Burns injuries & poisonings Both 0.3388 1.04 0.958,1.13 578 5796 0.3388 1.04 0.957,1.14 563 5594
1001 Foreign body injury injuries & poisonings Both 0.6745 1.01 0.955,1.07 1199 12007 0.6622 1.01 0.954,1.08 1144 11630
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.9817 1.0 0.973,1.03 5480 54819 0.9908 1.0 0.972,1.03 5237 52687
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.7482 1.02 0.907,1.15 300 2997 0.7129 1.02 0.908,1.15 292 2882
1005 Other symptoms injuries & poisonings Both 0.3954 1.02 0.97,1.08 1444 14422 0.5383 1.02 0.963,1.08 1375 13869
1006 Crushing injury injuries & poisonings Both 0.002692 0.822 0.724,0.934 256 2558 0.003631 0.824 0.724,0.939 245 2476
1007 Injury to blood vessels injuries & poisonings Both 0.03467 0.873 0.77,0.99 256 2559 0.02818 0.867 0.762,0.985 249 2478
1008 Crushing or internal injury to organs injuries & poisonings Both 0.4207 0.974 0.913,1.04 1013 10132 0.4305 0.974 0.912,1.04 964 9771
1009 Injury, NOS injuries & poisonings Both 0.7311 0.996 0.974,1.02 8482 84911 0.8128 0.997 0.975,1.02 8207 82098
1010 Other tests injuries & poisonings Both 0.2443 1.02 0.989,1.04 5945 59512 0.2168 1.02 0.99,1.05 5692 57250
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.3199 0.989 0.968,1.01 9152 91588 0.4295 0.991 0.97,1.01 8702 87961
1012 Late effect injuries & poisonings Both 0.8375 1.02 0.846,1.23 105 1057 0.7278 1.03 0.855,1.25 102 1014
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.1986 1.08 0.961,1.21 316 3168 0.2371 1.07 0.954,1.21 305 3051
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.7709 1.04 0.806,1.34 66 659 0.9078 0.985 0.762,1.27 64 632
1015 Effects of other external causes injuries & poisonings Both 0.8872 1.0 0.971,1.03 4226 42294 0.6745 1.01 0.975,1.04 4026 40821
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.7015 1.0 0.987,1.02 15895 159019 0.6252 0.996 0.979,1.01 14883 153567
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LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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