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MGI PRS for Melanomas of skin, dx or hx(172.1) based on UKB GWAS (FINNGEN)
GWAS reference: !UKB_GWAS GWAS source: UKB GWAS (FINNGEN) PRS method: P_5e-08
PRSweb LD reference: UKB GWAS phenotype: Malignant melanoma of skin PRSweb date: 2020-06-20
GWAS ID: C3_MELANOMA_SKIN GWAS URL: http://www.nealelab.is/uk-biobank Genome build: GRCh37/hg19
PRS tuning parameter: P<=5e-08 PRS evaluation in: MGI
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.7656 0.994 0.952,1.04 2317 23065 0.631 0.981 0.909,1.06 742 7515
008.5 Bacterial enteritis infectious diseases Both 0.9057 0.996 0.936,1.06 1090 10875 0.6546 1.02 0.941,1.1 685 7065
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.9311 0.997 0.931,1.07 896 8939 0.6546 1.02 0.941,1.1 685 7065
008.6 Viral Enteritis infectious diseases Both 0.7674 1.01 0.931,1.1 590 5900 0.618 1.02 0.932,1.13 469 4968
010 Tuberculosis infectious diseases Both 0.5333 0.954 0.823,1.11 195 1948 0.6471 0.995 0.973,1.02 15255 16004
031 Diseases due to other mycobacteria infectious diseases Both 0.7112 0.957 0.76,1.21 73 722 0.6982 0.946 0.716,1.25 51 586
038 Septicemia infectious diseases Both 0.2559 1.03 0.981,1.07 2043 20052 0.2851 1.04 0.966,1.12 724 7308
038.1 Gram negative septicemia infectious diseases Both 0.1479 1.07 0.976,1.17 459 4559 0.743 1.02 0.914,1.13 342 3475
038.2 Gram positive septicemia infectious diseases Both 0.3597 1.07 0.926,1.24 184 1840 0.3097 1.09 0.925,1.28 149 1447
038.3 Bacteremia infectious diseases Both 0.2985 1.04 0.97,1.1 955 9489 0.2851 1.04 0.966,1.12 724 7308
041 Bacterial infection NOS infectious diseases Both 0.5 1.01 0.98,1.04 4641 32299 0.8072 0.981 0.84,1.15 182 1786
041.1 Staphylococcus infections infectious diseases Both 0.1334 1.04 0.987,1.1 1390 13828 0.04898 1.09 1.0,1.19 516 5228
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.335 1.04 0.962,1.12 714 7071 0.2208 1.05 0.969,1.15 569 5749
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.1365 1.06 0.981,1.15 639 6376 0.04898 1.09 1.0,1.19 516 5228
041.2 Streptococcus infection infectious diseases Both 0.1694 0.961 0.907,1.02 1316 13131 0.9954 0.999 0.852,1.17 161 1558
041.21 Rheumatic fever / chorea infectious diseases Both 0.3733 0.937 0.811,1.08 205 2047 0.9954 0.999 0.852,1.17 161 1558
041.4 E. coli infectious diseases Both 0.5585 0.98 0.918,1.05 949 9462 0.881 1.01 0.935,1.08 766 7406
041.8 H. pylori infectious diseases Both 0.7015 0.971 0.833,1.13 190 1892 0.7603 0.973 0.818,1.16 153 1509
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.4375 0.946 0.823,1.09 228 2265 0.8072 0.981 0.84,1.15 182 1786
053 Herpes zoster infectious diseases Both 0.5483 0.982 0.925,1.04 1184 11746 0.8433 0.981 0.814,1.18 124 1288
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.778 1.02 0.874,1.2 166 1655 0.8433 0.981 0.814,1.18 124 1288
054 Herpes simplex infectious diseases Both 0.975 1.0 0.944,1.06 1235 12278 0.4256 0.974 0.913,1.04 972 10461
070 Viral hepatitis infectious diseases Both 0.6053 0.979 0.904,1.06 661 6584 0.1862 1.05 0.975,1.14 682 7405
070.1 Viral hepatitis A infectious diseases Both 0.5741 0.933 0.732,1.19 67 660 0.3908 0.885 0.67,1.17 52 507
070.2 Viral hepatitis B infectious diseases Both 0.3296 0.922 0.783,1.09 162 1620 0.236 0.892 0.739,1.08 122 1309
070.3 Viral hepatitis C infectious diseases Both 0.9931 1.0 0.906,1.1 439 4366 0.6714 1.02 0.919,1.14 358 3534
070.4 Chronic hepatitis infectious diseases Both 0.06026 1.16 0.993,1.36 161 1610 0.1581 1.14 0.949,1.38 117 1299
070.9 Hepatitis NOS infectious diseases Both 0.1875 1.05 0.978,1.12 924 9231 0.1862 1.05 0.975,1.14 682 7405
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.7621 0.971 0.801,1.18 122 1220 0.861 0.979 0.774,1.24 74 794
071.1 HIV infection, symptomatic infectious diseases Both 0.4667 0.924 0.746,1.14 95 950 0.861 0.979 0.774,1.24 74 794
078 Viral warts & HPV infectious diseases Both 0.1718 1.03 0.988,1.07 2651 24185 0.3228 1.02 0.978,1.07 2007 20521
079 Viral infection infectious diseases Both 0.01698 1.04 1.01,1.07 5061 29504 0.9462 1.0 0.913,1.1 464 4904
079.1 Varicella infection infectious diseases Both 0.002138 1.06 1.02,1.1 2940 25647 0.2535 1.03 0.98,1.08 1666 21269
079.2 Infectious mononucleosis infectious diseases Both 0.2443 0.918 0.796,1.06 213 2093 0.5754 0.958 0.823,1.11 181 1918
079.9 Viremia, NOS infectious diseases Both 0.2455 1.05 0.966,1.14 579 5713 0.9462 1.0 0.913,1.1 464 4904
080 Postoperative infection infectious diseases Both 0.2735 1.02 0.982,1.06 2586 25769 0.6209 1.01 0.966,1.06 1943 20770
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.4498 0.979 0.925,1.04 1364 13616 0.4093 0.974 0.915,1.04 1113 10951
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.157 0.945 0.875,1.02 700 6990 0.1866 0.944 0.867,1.03 573 6025
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.1592 1.03 0.988,1.07 2379 23308 0.2786 1.09 0.936,1.26 179 1867
110.1 Dermatophytosis infectious diseases Both 0.08913 1.04 0.994,1.09 2164 21163 0.4613 1.04 0.94,1.15 420 4611
110.11 Dermatophytosis of nail infectious diseases Both 0.542 1.02 0.961,1.08 1264 12489 0.9311 1.0 0.937,1.07 921 9723
110.12 Althete's foot infectious diseases Both 0.0955 1.07 0.988,1.17 593 5884 0.6592 1.02 0.926,1.13 412 4592
110.13 Dermatophytosis of the body infectious diseases Both 0.4457 1.03 0.949,1.13 570 5682 0.4613 1.04 0.94,1.15 420 4611
110.2 Dermatomycoses infectious diseases Both 0.1667 0.916 0.809,1.04 283 2812 0.3443 0.935 0.815,1.07 223 2384
112 Candidiasis infectious diseases Both 0.07762 1.03 0.996,1.07 2931 25310 0.3289 1.05 0.952,1.16 409 4371
112.3 Candidiasis of skin and nails infectious diseases Both 0.1245 1.07 0.982,1.17 546 5450 0.3289 1.05 0.952,1.16 409 4371
117 Mycoses infectious diseases Both 0.9462 0.997 0.909,1.09 494 4925 0.413 1.1 0.878,1.37 80 855
117.1 Histoplasmosis infectious diseases Both 0.6026 1.07 0.837,1.36 66 660 0.2704 1.16 0.89,1.52 56 518
117.4 Aspergillosis infectious diseases Both 0.955 0.994 0.81,1.22 105 1045 0.413 1.1 0.878,1.37 80 855
130 Spirochetal infection infectious diseases Both 0.1202 1.15 0.963,1.38 118 1177 0.7161 1.05 0.817,1.34 66 712
130.1 Lyme disease infectious diseases Both 0.173 1.17 0.935,1.45 86 860 0.7161 1.05 0.817,1.34 66 712
132 Infestation (lice, mites) infectious diseases Both 0.07586 0.854 0.718,1.02 146 1460 0.1923 0.883 0.731,1.06 121 1262
134 Helminthiases infectious diseases Both 0.6918 0.944 0.711,1.25 54 540 ,
136 Other infectious and parasitic diseases infectious diseases Both 0.4055 1.02 0.976,1.06 2438 24314 0.7621 0.993 0.946,1.04 1825 19785
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.6918 0.988 0.93,1.05 1166 11657 0.9441 0.998 0.932,1.07 937 9070
145 Cancer of mouth neoplasms Both 0.9268 0.997 0.94,1.06 1182 11759 0.4753 0.908 0.696,1.18 57 1378
145.1 Cancer of lip neoplasms Both 0.3639 1.12 0.878,1.42 69 690 ,
145.2 Cancer of tongue neoplasms Both 0.8241 0.99 0.907,1.08 550 5486 0.5433 0.96 0.843,1.09 240 4313
145.3 Cancer of major salivary glands neoplasms Both 0.4276 0.954 0.848,1.07 310 3093 0.07413 0.853 0.716,1.02 144 2347
145.4 Cancer of the gums neoplasms Both 0.3776 1.08 0.911,1.28 143 1419 ,
145.5 Cancer of the mouth floor neoplasms Both 0.9616 0.996 0.853,1.16 173 1723 0.4753 0.908 0.696,1.18 57 1378
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.08318 0.947 0.89,1.01 1124 11202 0.2193 0.873 0.703,1.08 87 1591
149.1 Cancer of oropharynx neoplasms Both 0.4624 0.955 0.846,1.08 291 2892 0.5105 0.942 0.789,1.12 134 2281
149.2 Cancer of nasopharynx neoplasms Both 0.03388 0.779 0.618,0.981 87 855 0.1119 0.796 0.601,1.05 53 693
149.3 Cancer of hypopharynx neoplasms Both 0.7691 0.964 0.753,1.23 68 680 ,
149.4 Cancer of larynx neoplasms Both 0.8511 0.989 0.884,1.11 332 3314 0.6324 0.966 0.838,1.11 205 2602
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.1556 0.936 0.854,1.03 505 5041 0.2864 0.926 0.803,1.07 202 3909
149.9 Cancer of of nasal cavities neoplasms Both 0.1888 0.909 0.789,1.05 208 2067 0.2193 0.873 0.703,1.08 87 1591
150 Cancer of esophagus neoplasms Both 0.2786 0.942 0.846,1.05 378 3776 0.5559 0.964 0.853,1.09 294 2905
151 Cancer of stomach neoplasms Both 0.5445 1.03 0.933,1.14 430 4292 0.8204 1.01 0.905,1.13 345 3289
153 Colorectal cancer neoplasms Both 0.5902 1.02 0.958,1.08 1196 11882 0.2056 1.06 0.967,1.17 461 5204
153.2 Colon cancer neoplasms Both 0.9484 1.0 0.938,1.07 941 9327 0.8147 1.01 0.933,1.09 681 7130
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.2582 1.05 0.967,1.13 669 6663 0.2056 1.06 0.967,1.17 461 5204
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.7798 1.01 0.918,1.12 418 4180 0.3715 0.936 0.811,1.08 210 2230
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.6053 0.968 0.857,1.09 285 2850 0.3715 0.936 0.811,1.08 210 2230
157 Pancreatic cancer neoplasms Both 0.2559 1.06 0.959,1.17 430 4292 0.2636 1.06 0.954,1.19 344 3285
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.7244 1.01 0.956,1.07 1369 13455 0.5521 1.02 0.956,1.09 969 10494
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.1486 1.06 0.981,1.13 779 7785 0.05012 1.15 1.0,1.32 200 2062
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.618 0.962 0.824,1.12 183 1830 0.9226 0.991 0.832,1.18 140 1431
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.02884 1.21 1.02,1.44 133 1330 0.02399 1.25 1.03,1.52 103 1014
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.07943 1.12 0.987,1.26 255 2550 0.05012 1.15 1.0,1.32 200 2062
164 Cancer of intrathoracic organs neoplasms Both 0.271 0.891 0.726,1.09 111 1110 0.6281 0.938 0.723,1.22 65 860
165 Cancer within the respiratory system neoplasms Both 0.6871 0.986 0.922,1.05 945 9436 0.6745 0.982 0.902,1.07 583 6485
165.1 Cancer of bronchus; lung neoplasms Both 0.7261 0.988 0.921,1.06 874 8724 0.6745 0.982 0.902,1.07 583 6485
170 Cancer of bone and connective tissue neoplasms Both 0.0195 1.06 1.01,1.12 1538 15304 0.455 0.967 0.887,1.06 540 8540
170.1 Bone cancer neoplasms Both 0.5728 1.02 0.945,1.11 668 6660 0.5957 0.971 0.869,1.08 339 5247
170.2 Cancer of connective tissue neoplasms Both 0.07244 1.06 0.995,1.12 1097 10941 0.455 0.967 0.887,1.06 540 8540
172 Skin cancer neoplasms Both 7.943E-60 1.25 1.22,1.28 7099 27878 ,
172.1 Melanomas of skin, dx or hx neoplasms Both 2.512E-53 1.35 1.3,1.41 2701 21867 ,
172.11 Melanomas of skin neoplasms Both 2.512E-51 1.35 1.3,1.41 2624 21526 ,
172.2 Other non-epithelial cancer of skin neoplasms Both 1.259E-49 1.24 1.21,1.28 5888 25669 ,
172.21 Basal cell carcinoma neoplasms Both 1.585E-37 1.28 1.23,1.33 2988 20068 ,
172.22 Squamous cell carcinoma neoplasms Both 3.162E-27 1.29 1.23,1.35 1917 14585 ,
172.3 Carcinoma in situ of skin neoplasms Both 3.981E-27 1.37 1.3,1.46 1215 10290 ,
173 Neoplasm of uncertain behavior of skin neoplasms Both 5.012E-13 1.21 1.15,1.27 1575 15093 0.00871 1.11 1.03,1.19 675 15093
174 Breast cancer neoplasms Both 0.3119 1.02 0.98,1.07 2694 13131 0.875 0.987 0.841,1.16 162 1659
174.1 Breast cancer [female] neoplasms Female 0.4055 1.02 0.976,1.06 2605 12548 0.6966 1.01 0.962,1.06 1997 10564
174.11 Malignant neoplasm of female breast neoplasms Female 0.3837 1.02 0.976,1.06 2565 12510 0.6966 1.01 0.962,1.06 1997 10564
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.8375 0.985 0.853,1.14 206 2051 0.875 0.987 0.841,1.16 162 1659
175 Acquired absence of breast neoplasms Female 0.6668 1.01 0.95,1.08 978 9172 0.826 1.01 0.938,1.08 810 7758
180 Cervical cancer and dysplasia neoplasms Female 0.561 1.02 0.959,1.08 1182 10494 0.7379 0.987 0.916,1.06 745 6960
180.1 Cervical cancer neoplasms Female 0.5188 1.03 0.936,1.14 430 4300 0.8204 1.01 0.909,1.13 358 3664
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.826 1.01 0.939,1.08 857 7886 0.7379 0.987 0.916,1.06 745 6960
182 Malignant neoplasm of uterus neoplasms Female 0.138 1.06 0.981,1.15 643 6390 0.1016 1.08 0.986,1.17 530 5105
184 Cancer of other female genital organs neoplasms Female 0.2249 1.04 0.975,1.12 910 8957 0.7568 1.02 0.915,1.13 372 4284
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.3846 1.04 0.95,1.14 491 4888 0.3606 1.06 0.94,1.18 310 3000
184.11 Malignant neoplasm of ovary neoplasms Female 0.4236 1.04 0.939,1.16 367 3659 0.3606 1.06 0.94,1.18 310 3000
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.2649 1.05 0.962,1.15 526 5253 0.7568 1.02 0.915,1.13 372 4284
185 Cancer of prostate neoplasms Male 3.981E-4 0.918 0.875,0.962 2432 8825 0.002754 0.918 0.869,0.971 1792 6683
187 Cancer of other male genital organs neoplasms Male 0.5572 1.04 0.92,1.17 276 2723 0.02291 1.24 1.03,1.49 116 1171
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.3597 0.905 0.731,1.12 96 960 0.7798 1.04 0.791,1.37 52 674
187.2 Malignant neoplasm of testis neoplasms Male 0.002512 1.29 1.09,1.52 144 1387 0.02291 1.24 1.03,1.49 116 1171
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.492 0.986 0.946,1.03 2552 20553 0.7798 0.986 0.896,1.09 468 4028
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.6607 1.01 0.957,1.07 1261 12588 0.6622 1.04 0.88,1.22 159 1396
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.6622 0.986 0.927,1.05 1083 10823 0.8472 1.01 0.939,1.08 857 8058
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.9311 1.01 0.873,1.16 202 2010 0.6622 1.04 0.88,1.22 159 1396
189.2 Cancer of bladder neoplasms Both 0.0537 0.949 0.9,1.0 1575 13516 0.2393 0.963 0.905,1.03 1143 9102
189.21 Malignant neoplasm of bladder neoplasms Both 0.03467 0.943 0.892,0.996 1456 12558 0.2393 0.963 0.905,1.03 1143 9102
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.3221 0.958 0.881,1.04 601 5841 0.7798 0.986 0.896,1.09 468 4028
190 Cancer of eye neoplasms Both 0.7834 0.974 0.806,1.18 114 1125 ,
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.139 1.05 0.984,1.13 904 9040 0.8318 1.01 0.912,1.12 386 3977
191.1 Cancer of brain and nervous system neoplasms Both 0.07762 1.08 0.992,1.18 580 5800 0.8318 1.01 0.912,1.12 386 3977
191.11 Cancer of brain neoplasms Both 0.4111 1.04 0.948,1.14 483 4830 0.8318 1.01 0.912,1.12 386 3977
193 Thyroid cancer neoplasms Both 0.6653 0.984 0.915,1.06 798 7953 0.2427 0.953 0.879,1.03 646 6603
194 Cancer of other endocrine glands neoplasms Both 0.5408 1.04 0.909,1.2 221 2207 0.1213 1.13 0.969,1.31 180 1762
195 Cancer, suspected or other neoplasms Both 1.479E-7 1.06 1.04,1.09 12134 23141 0.7396 0.982 0.883,1.09 354 7894
195.1 Malignant neoplasm, other neoplasms Both 1.905E-8 1.07 1.04,1.1 11693 23098 0.4111 1.01 0.984,1.04 7136 21246
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.04169 1.07 1.0,1.14 970 8963 0.7396 0.982 0.883,1.09 354 7894
196 Radiotherapy neoplasms Both 0.3048 1.02 0.978,1.07 2067 15612 0.3491 0.973 0.919,1.03 1289 14004
197 Chemotherapy neoplasms Both 0.001023 1.06 1.02,1.1 4051 21210 0.857 0.996 0.957,1.04 2828 19391
198 Secondary malignant neoplasm neoplasms Both 1.288E-7 1.09 1.05,1.12 4986 21474 0.4887 0.965 0.872,1.07 418 6143
198.1 Secondary malignancy of lymph nodes neoplasms Both 2.455E-10 1.13 1.09,1.17 3156 19844 0.3556 1.02 0.974,1.08 1632 18056
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.7568 1.01 0.944,1.08 903 8847 0.0182 0.898 0.822,0.982 538 7899
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.00912 1.11 1.03,1.19 725 7166 0.3648 1.04 0.954,1.14 537 6355
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.006457 1.12 1.03,1.21 643 6395 0.912 0.995 0.904,1.09 443 5704
198.5 Secondary malignancy of brain/spine neoplasms Both 0.04467 1.09 1.0,1.19 545 5421 0.1614 0.916 0.81,1.04 279 4841
198.6 Secondary malignancy of bone neoplasms Both 0.4764 1.03 0.952,1.11 712 6962 0.4887 0.965 0.872,1.07 418 6143
198.7 Secondary malignant neoplasm of skin neoplasms Both 1.862E-5 1.29 1.15,1.45 287 2752 ,
199 Neoplasm of uncertain behavior neoplasms Both 0.0871 1.03 0.996,1.06 4947 22823 0.7534 0.958 0.734,1.25 57 686
199.4 Neurofibromatosis neoplasms Both 0.4955 1.09 0.856,1.38 72 720 0.7534 0.958 0.734,1.25 57 686
200 Myeloproliferative disease neoplasms Both 0.7691 0.99 0.924,1.06 886 8851 0.2799 0.896 0.735,1.09 118 1279
200.1 Polycythemia vera neoplasms Both 0.9462 1.01 0.853,1.19 161 1610 0.2799 0.896 0.735,1.09 118 1279
201 Hodgkin's disease neoplasms Both 0.5358 0.945 0.792,1.13 138 1373 0.8851 0.985 0.8,1.21 96 1116
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.8954 0.996 0.942,1.05 1308 13070 0.5861 0.942 0.759,1.17 97 1004
202.2 Non-Hodgkins lymphoma neoplasms Both 0.4355 0.976 0.919,1.04 1141 11402 0.5861 0.942 0.759,1.17 97 1004
202.21 Nodular lymphoma neoplasms Both 0.8241 1.01 0.931,1.09 632 6320 0.3436 0.952 0.859,1.05 401 4920
202.22 Reticulosarcoma neoplasms Both 0.5309 0.945 0.792,1.13 137 1355 0.6138 0.947 0.765,1.17 97 1041
202.24 Large cell lymphoma neoplasms Both 0.4853 0.937 0.78,1.13 132 1300 0.5861 0.942 0.759,1.17 97 1004
204 Leukemia neoplasms Both 0.2679 1.05 0.963,1.15 545 5450 0.9204 0.99 0.821,1.19 113 1308
204.1 Lymphoid leukemia neoplasms Both 0.1009 1.13 0.976,1.31 187 1870 0.2716 1.14 0.905,1.42 74 987
204.11 Lymphoid leukemia, acute neoplasms Both 0.1905 1.19 0.918,1.53 58 580 ,
204.12 Lymphoid leukemia, chronic neoplasms Both 0.1211 1.14 0.965,1.36 136 1350 0.2716 1.14 0.905,1.42 74 987
204.2 Myeloid leukemia neoplasms Both 0.8337 1.02 0.88,1.17 206 2060 0.7674 0.968 0.779,1.2 86 962
204.21 Myeloid leukemia, acute neoplasms Both 0.6699 1.04 0.872,1.24 124 1240 0.7674 0.968 0.779,1.2 86 962
204.4 Multiple myeloma neoplasms Both 0.3614 1.07 0.925,1.24 180 1795 0.9204 0.99 0.821,1.19 113 1308
208 Benign neoplasm of colon neoplasms Both 0.103 0.979 0.955,1.0 8098 29324 0.2249 0.983 0.955,1.01 6220 24252
209 Neuroendocrine tumors neoplasms Both 0.4446 1.05 0.921,1.21 222 2220 0.9441 0.995 0.855,1.16 181 1741
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.3648 0.976 0.927,1.03 1584 15798 0.05623 0.939 0.881,1.0 1040 13056
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.9057 1.0 0.974,1.03 5807 30296 0.4634 1.01 0.981,1.04 4780 24812
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.8072 1.01 0.955,1.06 1556 15533 0.9247 1.0 0.945,1.06 1196 12399
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.8241 1.01 0.952,1.06 1405 13304 0.3436 0.971 0.913,1.03 1132 12096
214 Lipoma neoplasms Both 0.4198 0.975 0.917,1.04 1117 11124 0.811 0.989 0.905,1.08 533 5588
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.6714 0.983 0.908,1.06 681 6793 0.811 0.989 0.905,1.08 533 5588
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.1968 0.977 0.944,1.01 3594 32904 0.05888 0.962 0.924,1.0 2677 26935
216 Benign neoplasm of skin neoplasms Both 8.128E-10 1.08 1.05,1.1 9073 29036 0.9397 0.991 0.791,1.24 77 987
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.9594 0.995 0.822,1.2 111 1093 0.9397 0.991 0.791,1.24 77 987
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.004365 1.09 1.03,1.16 1150 11417 0.6138 0.977 0.892,1.07 487 9079
217.1 Nevus, non-neoplastic neoplasms Both 0.00871 1.09 1.02,1.15 1063 10579 0.6138 0.977 0.892,1.07 487 9079
218 Benign neoplasm of uterus neoplasms Female 0.2547 1.02 0.985,1.06 3552 13845 0.1216 1.03 0.991,1.08 2482 11626
218.1 Uterine leiomyoma neoplasms Female 0.4227 1.02 0.969,1.08 1506 13465 0.2529 1.03 0.976,1.09 1271 11368
218.2 Other benign neoplasm of uterus neoplasms Female 0.26 1.02 0.983,1.07 2824 13698 0.1216 1.03 0.991,1.08 2482 11626
220 Benign neoplasm of ovary neoplasms Female 0.5559 0.978 0.908,1.05 763 7571 0.5929 1.02 0.945,1.1 674 6479
221 Benign neoplasm of other female genital organs neoplasms Female 0.2051 1.03 0.982,1.09 1666 12074 0.1629 1.04 0.984,1.1 1425 10302
222 Benign neoplasm of male genital organs neoplasms Male 0.695 0.987 0.923,1.05 954 9116 0.4178 1.03 0.956,1.11 750 6653
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.4036 1.02 0.97,1.08 1547 11080 0.5675 1.02 0.96,1.08 1280 9878
224 Benign neoplasm of eye neoplasms Both 0.8072 0.989 0.904,1.08 511 5062 0.6281 0.971 0.862,1.09 293 3135
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.955 0.997 0.904,1.1 429 4230 0.6281 0.971 0.862,1.09 293 3135
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.877 1.01 0.943,1.07 1039 10379 0.8241 1.02 0.87,1.19 175 1959
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.7852 0.99 0.922,1.06 817 8160 0.8531 0.993 0.919,1.07 682 6629
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.1213 1.11 0.973,1.26 242 2420 0.8241 1.02 0.87,1.19 175 1959
226 Benign neoplasm of thyroid glands neoplasms Both 0.06166 0.942 0.884,1.0 1082 10810 0.03981 0.93 0.868,0.997 894 8855
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.9036 0.997 0.943,1.05 1387 13870 0.9462 1.0 0.895,1.13 328 3037
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.1138 1.09 0.98,1.2 375 3745 0.02692 1.14 1.01,1.27 309 2971
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.06918 0.926 0.853,1.01 644 6434 0.0309 0.906 0.829,0.991 549 5223
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.7943 0.986 0.885,1.1 373 3724 0.9462 1.0 0.895,1.13 328 3037
228 Hemangioma and lymphangioma, any site neoplasms Both 0.004571 1.08 1.02,1.14 1517 15150 0.7656 0.985 0.891,1.09 405 6575
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.004786 1.1 1.03,1.18 849 8478 0.7656 0.985 0.891,1.09 405 6575
229 Benign neoplasm of unspecified sites neoplasms Both 0.05129 1.03 1.0,1.05 6631 31223 0.2871 0.979 0.943,1.02 2989 24929
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.001905 1.05 1.02,1.08 4904 29712 0.2871 0.979 0.943,1.02 2989 24929
860 Bone marrow or stem cell transplant neoplasms Both 0.1038 1.16 0.971,1.38 127 1266 0.8511 1.02 0.819,1.27 85 996
240 Simple and unspecified goiter endocrine/metabolic Both 0.6714 0.984 0.914,1.06 767 7647 0.8831 1.01 0.928,1.09 629 6240
241 Nontoxic nodular goiter endocrine/metabolic Both 0.2046 0.972 0.93,1.02 2274 18240 0.5152 0.976 0.908,1.05 816 8184
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.302 0.975 0.928,1.02 1795 16440 0.3289 0.973 0.921,1.03 1411 13369
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.8035 0.992 0.93,1.06 1017 10065 0.5152 0.976 0.908,1.05 816 8184
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.9057 1.0 0.944,1.07 1075 10635 0.5675 0.943 0.771,1.15 102 984
242.1 Graves' disease endocrine/metabolic Both 0.9817 0.999 0.903,1.11 399 3965 0.9795 1.0 0.898,1.12 342 3308
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.6839 1.04 0.854,1.27 98 978 0.6871 1.05 0.843,1.3 84 793
242.3 Exophthalmos endocrine/metabolic Both 0.3631 0.941 0.825,1.07 245 2447 0.5675 0.943 0.771,1.15 102 984
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.6577 0.959 0.796,1.16 116 1160 0.5675 0.943 0.771,1.15 102 984
244 Hypothyroidism endocrine/metabolic Both 0.07586 0.975 0.948,1.0 6448 27183 0.05754 0.969 0.938,1.0 4743 21668
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.3972 0.977 0.925,1.03 1421 14153 0.1479 0.956 0.899,1.02 1126 11592
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.6546 0.984 0.918,1.06 853 8502 0.4457 0.969 0.895,1.05 641 6889
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.04898 0.971 0.944,1.0 5996 26719 0.05754 0.969 0.938,1.0 4743 21668
245 Thyroiditis endocrine/metabolic Both 0.8531 1.01 0.926,1.1 574 5720 0.9594 1.0 0.906,1.11 398 3854
245.2 Chronic thyroiditis endocrine/metabolic Both 0.9016 1.01 0.916,1.11 463 4617 0.9594 1.0 0.906,1.11 398 3854
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.8995 1.01 0.915,1.11 456 4533 0.9594 1.0 0.906,1.11 398 3854
246 Other disorders of thyroid endocrine/metabolic Both 0.1132 0.975 0.945,1.01 5018 25158 0.2911 0.948 0.858,1.05 417 4574
246.2 Thyroid cyst endocrine/metabolic Both 0.5636 1.07 0.858,1.33 83 804 0.4355 0.902 0.696,1.17 63 637
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.9397 0.997 0.916,1.08 568 5651 0.2911 0.948 0.858,1.05 417 4574
249 Secondary diabetes mellitus endocrine/metabolic Both 0.4887 1.03 0.951,1.11 686 6849 0.4732 1.03 0.944,1.13 500 5274
250 Diabetes mellitus endocrine/metabolic Both 0.9977 1.0 0.977,1.02 10115 27568 0.0263 0.909 0.837,0.989 624 6327
250.1 Type 1 diabetes endocrine/metabolic Both 0.5998 0.983 0.923,1.05 1053 10521 0.3565 0.876 0.661,1.16 54 541
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.02818 0.766 0.603,0.972 80 792 0.04266 0.756 0.577,0.991 63 662
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.1799 0.912 0.798,1.04 235 2346 0.0166 0.823 0.702,0.966 175 1895
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.2344 0.927 0.819,1.05 280 2800 0.2421 0.92 0.799,1.06 219 2295
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.9183 0.993 0.87,1.13 238 2372 0.2495 0.913 0.781,1.07 182 1924
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.6053 0.939 0.739,1.19 70 690 0.3565 0.876 0.661,1.16 54 541
250.2 Type 2 diabetes endocrine/metabolic Both 0.9661 0.999 0.973,1.03 7035 26169 0.6501 1.02 0.923,1.14 385 3689
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.02188 0.798 0.657,0.968 120 1200 0.04786 0.801 0.643,0.998 93 952
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.9616 0.999 0.94,1.06 1133 11056 0.5023 0.976 0.908,1.05 835 8283
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.0389 0.927 0.863,0.996 826 8208 0.02754 0.91 0.837,0.99 622 6256
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.3148 0.972 0.92,1.03 1419 13969 0.1496 0.955 0.896,1.02 1099 10681
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.955 1.0 0.917,1.1 513 5077 0.6501 1.02 0.923,1.14 385 3689
250.3 Insulin pump user endocrine/metabolic Both 0.537 1.02 0.968,1.06 1884 17814 0.9354 1.0 0.95,1.06 1464 13972
250.4 Abnormal glucose endocrine/metabolic Both 0.2917 1.02 0.986,1.05 5404 26451 0.1 1.03 0.994,1.07 3621 21128
250.41 Impaired fasting glucose endocrine/metabolic Both 0.6039 1.01 0.959,1.07 1326 13130 0.8414 1.01 0.944,1.07 1007 10219
250.42 Other abnormal glucose endocrine/metabolic Both 0.3532 1.01 0.984,1.05 4736 25883 0.1 1.03 0.994,1.07 3621 21128
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.0871 1.22 0.972,1.52 78 747 0.02951 1.31 1.03,1.66 69 626
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.4074 0.974 0.917,1.04 1137 11335 0.414 0.971 0.905,1.04 870 8651
250.7 Diabetic retinopathy endocrine/metabolic Both 0.04898 0.93 0.864,1.0 821 8168 0.0263 0.909 0.837,0.989 624 6327
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.7621 0.987 0.909,1.07 595 5901 0.5248 0.972 0.89,1.06 551 5676
251.1 Hypoglycemia endocrine/metabolic Both 0.6281 0.981 0.908,1.06 702 7015 0.5248 0.972 0.89,1.06 551 5676
252 Disorders of parathyroid gland endocrine/metabolic Both 0.5728 0.986 0.94,1.03 1807 17879 0.09772 0.91 0.813,1.02 329 3220
252.1 Hyperparathyroidism endocrine/metabolic Both 0.3873 0.978 0.93,1.03 1656 16459 0.271 0.969 0.916,1.02 1332 13173
252.2 Hypoparathyroidism endocrine/metabolic Both 0.1 0.917 0.828,1.02 393 3922 0.09772 0.91 0.813,1.02 329 3220
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.6138 1.02 0.943,1.1 691 6893 0.4325 1.11 0.856,1.44 60 694
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.0537 1.15 0.998,1.32 205 2041 0.2393 1.15 0.911,1.45 67 605
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.4819 1.09 0.863,1.37 72 720 0.2393 1.15 0.911,1.45 67 605
253.2 Pituitary hypofunction endocrine/metabolic Both 0.3475 1.07 0.926,1.24 184 1840 0.1671 1.12 0.954,1.31 149 1473
253.3 Diabetes insipidus endocrine/metabolic Both 0.7464 1.04 0.818,1.32 70 694 0.6714 1.06 0.812,1.38 62 561
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.1377 0.849 0.684,1.05 92 899 0.246 0.863 0.674,1.11 67 743
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.3258 1.11 0.9,1.37 93 925 0.4325 1.11 0.856,1.44 60 694
255 Disorders of adrenal glands endocrine/metabolic Both 0.3126 1.03 0.972,1.09 1186 11860 0.7178 1.02 0.915,1.14 351 3699
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.6266 0.971 0.862,1.09 290 2886 0.06607 1.22 0.987,1.51 87 835
255.11 Cushing's syndrome endocrine/metabolic Both 0.175 0.887 0.745,1.06 144 1440 0.3707 0.917 0.76,1.11 121 1219
255.12 Hyperaldosteronism endocrine/metabolic Both 0.2158 1.13 0.931,1.37 106 1057 0.06607 1.22 0.987,1.51 87 835
255.2 Adrenal hypofunction endocrine/metabolic Both 0.6761 1.02 0.929,1.12 477 4758 0.7178 1.02 0.915,1.14 351 3699
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.6776 1.02 0.927,1.12 451 4496 0.7178 1.02 0.915,1.14 351 3699
256 Ovarian dysfunction endocrine/metabolic Female 0.5998 1.02 0.95,1.09 859 8184 0.1435 1.07 0.978,1.17 519 4974
256.4 Polycystic ovaries endocrine/metabolic Female 0.0955 1.08 0.987,1.17 544 5436 0.1435 1.07 0.978,1.17 519 4974
257 Testicular dysfunction endocrine/metabolic Male 0.4217 1.03 0.957,1.11 747 7455 0.1371 1.07 0.979,1.17 537 5576
257.1 Testicular hypofunction endocrine/metabolic Male 0.3027 1.04 0.964,1.12 725 7234 0.1371 1.07 0.979,1.17 537 5576
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.3034 1.14 0.89,1.46 66 660 0.4742 0.92 0.733,1.16 82 817
258.1 Postablative ovarian failure endocrine/metabolic Female 0.1884 0.862 0.69,1.08 92 920 0.4742 0.92 0.733,1.16 82 817
259 Other endocrine disorders endocrine/metabolic Both 0.3412 0.964 0.893,1.04 759 7562 0.2443 0.951 0.874,1.03 622 6228
260 Protein-calorie malnutrition endocrine/metabolic Both 0.9354 1.0 0.96,1.05 2353 22279 0.9419 1.0 0.916,1.1 494 5153
260.1 Cachexia endocrine/metabolic Both 0.01778 0.844 0.734,0.971 239 2388 0.03802 0.84 0.712,0.99 174 1844
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.6412 0.987 0.933,1.04 1363 13589 0.5943 0.968 0.86,1.09 295 3255
260.22 Nutritional marasmus endocrine/metabolic Both 0.6934 0.98 0.886,1.08 413 4130 0.5943 0.968 0.86,1.09 295 3255
260.3 Adult failure to thrive endocrine/metabolic Both 0.1567 0.935 0.852,1.03 509 5051 0.1089 0.915 0.821,1.02 380 3815
260.6 Anorexia endocrine/metabolic Both 0.3192 1.04 0.963,1.12 677 6722 0.9419 1.0 0.916,1.1 494 5153
261 Vitamin deficiency endocrine/metabolic Both 0.191 0.981 0.953,1.01 5614 30157 0.8551 0.997 0.965,1.03 4337 24501
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.5 0.973 0.897,1.05 649 6482 0.6012 0.976 0.89,1.07 507 5120
261.4 Vitamin D deficiency endocrine/metabolic Both 0.2723 0.984 0.955,1.01 5264 29859 0.8551 0.997 0.965,1.03 4337 24501
262 Mineral deficiency NEC endocrine/metabolic Both 0.871 0.994 0.927,1.07 854 8532 0.3404 0.963 0.89,1.04 683 6970
263 Other nutritional deficiency endocrine/metabolic Both 0.597 0.973 0.879,1.08 412 4113 1.0 1.0 0.892,1.12 325 3286
264 Lack of normal physiological development endocrine/metabolic Both 0.2223 0.902 0.765,1.06 175 1735 0.2844 0.858 0.648,1.14 57 563
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.01445 0.764 0.615,0.948 95 950 0.2388 0.868 0.686,1.1 77 771
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.5333 0.919 0.704,1.2 61 607 0.2844 0.858 0.648,1.14 57 563
269 Proteinuria endocrine/metabolic Both 0.4688 1.02 0.961,1.09 1079 10768 0.9484 1.0 0.933,1.08 821 8528
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.5834 1.02 0.948,1.1 740 7378 0.413 1.07 0.911,1.25 167 1714
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.9462 1.01 0.838,1.21 129 1283 0.6839 0.955 0.766,1.19 88 838
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.869 0.983 0.797,1.21 101 998 0.6839 0.955 0.766,1.19 88 838
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.4909 1.08 0.871,1.33 81 810 0.1892 1.16 0.928,1.46 70 664
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.673 1.02 0.935,1.11 560 5581 0.413 1.07 0.911,1.25 167 1714
270.32 Paraproteinemia endocrine/metabolic Both 0.9462 0.996 0.886,1.12 301 2982 0.3508 0.931 0.802,1.08 193 2144
270.33 Amyloidosis endocrine/metabolic Both 0.413 0.89 0.673,1.18 55 550 ,
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.5675 1.04 0.905,1.2 218 2178 0.413 1.07 0.911,1.25 167 1714
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.2529 1.03 0.981,1.08 1952 19491 0.5675 0.931 0.728,1.19 66 687
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.1679 1.03 0.986,1.08 1885 18823 0.0257 1.06 1.01,1.12 1481 14895
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.3622 0.901 0.72,1.13 81 810 0.5675 0.931 0.728,1.19 66 687
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.07762 0.98 0.958,1.0 14793 22696 0.7907 0.979 0.836,1.15 164 1825
272.1 Hyperlipidemia endocrine/metabolic Both 0.08128 0.98 0.958,1.0 14763 22682 0.8492 0.995 0.945,1.05 1710 12235
272.11 Hypercholesterolemia endocrine/metabolic Both 0.6383 0.992 0.96,1.03 4668 18640 0.8551 0.996 0.959,1.04 3391 15109
272.12 Hyperglyceridemia endocrine/metabolic Both 0.1622 0.953 0.891,1.02 945 9395 0.3436 0.964 0.895,1.04 758 7327
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.2992 0.977 0.934,1.02 2272 15492 0.8492 0.995 0.945,1.05 1710 12235
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.5984 0.966 0.847,1.1 244 2425 0.7907 0.979 0.836,1.15 164 1825
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.1327 0.965 0.921,1.01 1971 18337 0.00257 0.709 0.566,0.887 99 988
274.1 Gout endocrine/metabolic Both 0.1268 0.963 0.919,1.01 1879 17712 0.00537 0.884 0.81,0.964 589 5957
274.11 Gouty arthropathy endocrine/metabolic Both 0.01479 0.912 0.848,0.982 793 7891 0.00537 0.884 0.81,0.964 589 5957
274.2 Crystal arthropathies endocrine/metabolic Both 0.07244 0.852 0.715,1.01 146 1425 0.00257 0.709 0.566,0.887 99 988
274.21 Chondrocalcinosis endocrine/metabolic Both 0.1663 0.881 0.736,1.05 140 1363 0.00257 0.709 0.566,0.887 99 988
275 Disorders of mineral metabolism endocrine/metabolic Both 0.2259 0.978 0.943,1.01 3252 30253 0.4457 0.93 0.772,1.12 127 1334
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.7295 0.988 0.92,1.06 845 8441 0.929 0.996 0.919,1.08 648 6651
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.08128 0.964 0.925,1.0 2502 24757 0.695 0.986 0.917,1.06 813 8066
275.51 Hypocalcemia endocrine/metabolic Both 0.2773 0.958 0.888,1.03 722 7203 0.4276 0.966 0.888,1.05 581 5867
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 1.0 1.0 0.939,1.07 1024 10193 0.695 0.986 0.917,1.06 813 8066
275.6 Hypercalcemia endocrine/metabolic Both 0.1714 0.956 0.897,1.02 1043 10415 0.1318 0.946 0.879,1.02 806 8255
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.4295 1.01 0.985,1.04 7227 30901 0.6745 0.954 0.766,1.19 84 838
276.1 Electrolyte imbalance endocrine/metabolic Both 0.8222 1.0 0.973,1.03 4833 28673 0.5585 1.02 0.96,1.08 1253 12850
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.7907 0.986 0.891,1.09 415 4115 0.8017 1.01 0.906,1.14 326 3190
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.7834 0.993 0.947,1.04 1857 17982 0.2138 0.965 0.911,1.02 1337 13918
276.13 Hyperpotassemia endocrine/metabolic Both 0.861 1.0 0.961,1.05 2238 20576 0.6966 0.99 0.941,1.04 1656 16127
276.14 Hypopotassemia endocrine/metabolic Both 0.743 1.01 0.959,1.06 1626 16160 0.5585 1.02 0.96,1.08 1253 12850
276.4 Acid-base balance disorder endocrine/metabolic Both 0.5176 0.983 0.933,1.04 1593 15855 0.743 1.02 0.9,1.16 256 2757
276.41 Acidosis endocrine/metabolic Both 0.4677 0.979 0.926,1.04 1357 13508 0.5943 0.983 0.922,1.05 1059 10725
276.42 Alkalosis endocrine/metabolic Both 0.7079 1.02 0.916,1.14 350 3498 0.743 1.02 0.9,1.16 256 2757
276.5 Hypovolemia endocrine/metabolic Both 0.455 1.01 0.979,1.05 3615 28901 0.6138 1.01 0.971,1.05 2667 23703
276.6 Fluid overload endocrine/metabolic Both 0.3811 1.03 0.966,1.1 1046 10404 0.4385 1.03 0.957,1.11 795 7928
276.8 Polydipsia endocrine/metabolic Both 0.9099 0.988 0.807,1.21 99 990 0.6745 0.954 0.766,1.19 84 838
277 Other disorders of metabolism endocrine/metabolic Both 0.01514 0.937 0.889,0.987 1534 15324 0.3715 0.959 0.874,1.05 509 4980
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.2541 0.925 0.81,1.06 252 2520 0.2541 0.914 0.782,1.07 186 1933
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.02884 0.905 0.827,0.99 547 5456 0.04786 0.901 0.812,0.999 417 4349
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.7603 0.988 0.912,1.07 675 6743 0.2188 0.94 0.853,1.04 455 4557
277.51 Lipoprotein disorders endocrine/metabolic Both 0.2143 0.946 0.867,1.03 567 5665 0.2188 0.94 0.853,1.04 455 4557
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.1986 0.946 0.869,1.03 610 6090 0.3715 0.959 0.874,1.05 509 4980
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.6095 0.995 0.974,1.02 15130 23191 0.9705 0.999 0.943,1.06 1287 11387
278.1 Obesity endocrine/metabolic Both 0.9772 1.0 0.979,1.02 13507 23193 0.2729 1.02 0.987,1.05 5435 18665
278.11 Morbid obesity endocrine/metabolic Both 0.5848 1.01 0.98,1.04 6376 23143 0.2729 1.02 0.987,1.05 5435 18665
278.3 Localized adiposity endocrine/metabolic Both 0.4436 0.952 0.839,1.08 270 2694 0.492 0.954 0.834,1.09 236 2203
278.4 Abnormal weight gain endocrine/metabolic Both 0.9528 0.998 0.947,1.05 1522 13685 0.9705 0.999 0.943,1.06 1287 11387
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.302 0.977 0.936,1.02 2245 22393 0.3048 0.944 0.846,1.05 353 3706
279.1 Immunity deficiency endocrine/metabolic Both 0.4932 0.976 0.911,1.05 881 8792 0.2624 1.09 0.939,1.26 189 2051
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.2065 1.08 0.957,1.23 254 2540 0.2624 1.09 0.939,1.26 189 2051
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.0631 0.921 0.845,1.0 574 5735 0.1205 0.926 0.841,1.02 458 4750
279.7 Other immunological findings endocrine/metabolic Both 0.1679 0.977 0.945,1.01 3927 30734 0.2 0.976 0.94,1.01 3074 24955
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.2259 0.941 0.852,1.04 443 4423 0.3048 0.944 0.846,1.05 353 3706
275.1 Disorders of iron metabolism hematopoietic Both 0.3855 0.93 0.79,1.1 168 1680 0.4457 0.93 0.772,1.12 127 1334
275.11 Hereditary hemochromatosis hematopoietic Both 0.8204 0.972 0.762,1.24 70 700 ,
280 Iron deficiency anemias hematopoietic Both 0.826 1.0 0.969,1.04 3537 25593 0.133 0.952 0.894,1.01 1059 10690
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.6412 1.01 0.973,1.05 3410 25349 0.7145 0.992 0.953,1.03 2675 20591
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.2123 0.965 0.912,1.02 1361 13511 0.133 0.952 0.894,1.01 1059 10690
281 Other deficiency anemia hematopoietic Both 0.5176 1.03 0.933,1.15 387 3838 0.9908 1.0 0.854,1.17 156 1597
281.1 Megaloblastic anemia hematopoietic Both 0.4977 1.05 0.909,1.22 189 1875 0.7691 1.03 0.846,1.25 104 1025
281.11 Pernicious anemia hematopoietic Both 0.3606 1.11 0.892,1.37 84 830 0.2588 1.15 0.903,1.46 69 647
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.8395 1.02 0.857,1.21 135 1348 0.7691 1.03 0.846,1.25 104 1025
281.9 Deficiency anemias hematopoietic Both 0.8395 1.01 0.884,1.16 214 2110 0.9908 1.0 0.854,1.17 156 1597
282 Hereditary hemolytic anemias hematopoietic Both 0.4966 0.954 0.834,1.09 248 2443 0.1517 0.853 0.687,1.06 101 1101
282.8 Other hemoglobinopathies hematopoietic Both 0.5888 0.954 0.806,1.13 158 1541 0.2483 0.889 0.728,1.09 120 1241
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.3793 0.923 0.773,1.1 143 1420 0.1517 0.853 0.687,1.06 101 1101
283 Acquired hemolytic anemias hematopoietic Both 0.9354 1.01 0.843,1.2 130 1295 0.8551 0.981 0.794,1.21 93 1005
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.9462 0.99 0.752,1.3 54 532 ,
284 Aplastic anemia hematopoietic Both 0.7447 1.01 0.93,1.11 558 5545 0.5754 0.969 0.868,1.08 358 3820
284.1 Pancytopenia hematopoietic Both 0.9462 0.997 0.908,1.09 488 4847 0.5754 0.969 0.868,1.08 358 3820
285 Other anemias hematopoietic Both 0.7311 1.0 0.981,1.03 9426 28014 0.7745 1.01 0.917,1.12 412 4369
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.7962 0.995 0.954,1.04 2536 22457 0.798 1.01 0.96,1.05 1954 17925
285.2 Anemia of chronic disease hematopoietic Both 0.5093 1.02 0.966,1.07 1584 15823 0.7745 1.01 0.917,1.12 412 4369
285.21 Anemia in chronic kidney disease hematopoietic Both 0.861 0.993 0.918,1.07 673 6722 0.1279 0.931 0.849,1.02 496 5258
285.22 Anemia in neoplastic disease hematopoietic Both 0.3556 1.04 0.955,1.14 555 5536 0.7745 1.01 0.917,1.12 412 4369
286 Coagulation defects hematopoietic Both 0.542 0.988 0.952,1.03 3013 27144 0.984 1.0 0.924,1.08 667 6639
286.1 Congenital coagulation defects hematopoietic Both 0.9057 1.01 0.87,1.17 190 1889 0.04571 1.24 1.0,1.54 84 814
286.11 Von willebrand's disease hematopoietic Both 0.1742 0.835 0.644,1.08 64 640 0.1069 0.79 0.593,1.05 53 540
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.1023 1.18 0.968,1.44 98 973 0.04571 1.24 1.0,1.54 84 814
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.9016 1.0 0.963,1.04 2601 20964 0.8995 1.0 0.957,1.05 1920 16320
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.2249 1.17 0.906,1.52 60 590 0.1923 1.19 0.916,1.55 58 534
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.7943 1.02 0.883,1.18 186 1860 0.9908 0.999 0.848,1.18 145 1451
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.02754 1.25 1.02,1.52 92 906 0.02042 1.31 1.04,1.64 73 708
286.6 Defibrination syndrome hematopoietic Both 0.4436 0.982 0.937,1.03 1964 19522 0.695 0.99 0.939,1.04 1560 15485
286.7 Other and unspecified coagulation defects hematopoietic Both 0.4036 0.982 0.941,1.02 2349 23153 0.3296 0.976 0.931,1.02 1856 18457
286.8 Hypercoagulable state hematopoietic Both 0.8995 0.995 0.918,1.08 643 6420 0.743 1.02 0.928,1.11 510 5099
286.81 Primary hypercoagulable state hematopoietic Both 0.867 1.01 0.928,1.09 618 6179 0.743 1.02 0.928,1.11 510 5099
286.9 Abnormal coagulation profile hematopoietic Both 0.8995 1.0 0.938,1.08 890 8770 0.984 1.0 0.924,1.08 667 6639
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.5728 0.988 0.949,1.03 2575 22699 0.6252 1.03 0.921,1.15 338 3439
287.1 Spontaneous ecchymoses hematopoietic Both 0.6714 0.966 0.821,1.14 154 1532 0.1592 0.872 0.721,1.05 117 1237
287.3 Thrombocytopenia hematopoietic Both 0.4009 0.982 0.94,1.02 2297 20909 0.6252 1.03 0.921,1.15 338 3439
287.31 Primary thrombocytopenia hematopoietic Both 0.9311 0.996 0.907,1.09 481 4785 0.6223 1.03 0.924,1.14 377 3711
287.32 Secondary thrombocytopenia hematopoietic Both 0.7516 1.02 0.922,1.12 436 4360 0.6252 1.03 0.921,1.15 338 3439
287.4 Qualitative platelet defects hematopoietic Both 0.5585 1.07 0.85,1.35 76 760 ,
288 Diseases of white blood cells hematopoietic Both 0.8204 1.0 0.971,1.04 3850 30383 0.2506 0.888 0.726,1.09 107 1062
288.1 Decreased white blood cell count hematopoietic Both 0.4645 1.02 0.965,1.08 1252 12520 0.9354 1.0 0.927,1.09 664 7298
288.11 Neutropenia hematopoietic Both 0.8414 0.993 0.927,1.06 896 8960 0.9354 1.0 0.927,1.09 664 7298
288.2 Elevated white blood cell count hematopoietic Both 0.5395 1.01 0.975,1.05 3179 28632 0.5689 1.01 0.971,1.05 2491 23474
288.3 Eosinophilia hematopoietic Both 0.1514 0.872 0.724,1.05 128 1278 0.2506 0.888 0.726,1.09 107 1062
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.2183 0.964 0.909,1.02 1259 12554 0.1919 0.908 0.786,1.05 207 2170
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.07586 0.926 0.851,1.01 615 6123 0.05248 0.912 0.831,1.0 509 5093
289.4 Lymphadenitis hematopoietic Both 0.0257 1.04 1.01,1.08 3186 28420 0.4721 1.02 0.973,1.06 2209 23367
289.5 Diseases of spleen hematopoietic Both 0.743 0.981 0.874,1.1 313 3130 0.9683 0.997 0.874,1.14 239 2526
289.8 Polycythemia, secondary hematopoietic Both 0.4966 0.949 0.816,1.1 182 1820 0.3516 0.921 0.774,1.1 144 1456
289.9 Abnormality of red blood cells hematopoietic Both 0.1746 0.918 0.811,1.04 281 2776 0.1919 0.908 0.786,1.05 207 2170
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.3404 0.969 0.909,1.03 1040 9399 0.861 0.992 0.903,1.09 479 4879
290.1 Dementias mental disorders Both 0.1276 0.924 0.834,1.02 407 3816 0.9795 0.998 0.853,1.17 161 1563
290.11 Alzheimer's disease mental disorders Both 0.1496 0.861 0.703,1.06 104 984 0.1734 0.84 0.654,1.08 71 628
290.12 Dementia with cerebral degenerations mental disorders Both 0.3273 0.884 0.691,1.13 71 705 ,
290.13 Senile dementia mental disorders Both 0.4909 0.957 0.845,1.08 257 2376 0.9795 0.998 0.853,1.17 161 1563
290.16 Vascular dementia mental disorders Both 0.1396 0.805 0.604,1.07 53 508 ,
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.7656 1.01 0.933,1.1 634 6242 0.6237 1.02 0.93,1.13 447 4632
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.9247 0.996 0.919,1.08 642 6369 0.861 0.992 0.903,1.09 479 4879
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.867 0.996 0.951,1.04 1977 19673 0.695 0.988 0.932,1.05 1234 12367
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.8872 1.01 0.864,1.18 161 1610 0.8551 0.984 0.825,1.17 133 1440
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.1521 1.08 0.972,1.2 364 3634 0.07943 1.11 0.988,1.24 296 2980
291.8 Alteration of consciousness mental disorders Both 0.3846 0.977 0.927,1.03 1563 15497 0.695 0.988 0.932,1.05 1234 12367
292 Neurological disorders mental disorders Both 0.2018 0.979 0.949,1.01 4340 31695 0.798 1.03 0.845,1.24 109 1130
292.1 Aphasia/speech disturbance mental disorders Both 0.6823 1.01 0.96,1.06 1554 15459 0.7015 1.04 0.866,1.24 128 1311
292.11 Aphasia mental disorders Both 0.9661 0.998 0.912,1.09 516 5142 0.9727 1.0 0.905,1.11 407 4037
292.12 Symbolic dysfunction mental disorders Both 0.9247 0.992 0.844,1.17 162 1620 0.7015 1.04 0.866,1.24 128 1311
292.2 Mild cognitive impairment mental disorders Both 0.0309 0.87 0.767,0.988 276 2716 0.4864 0.948 0.815,1.1 188 1902
292.3 Memory loss mental disorders Both 0.07244 0.951 0.9,1.0 1405 13752 0.2265 0.961 0.901,1.02 1037 10514
292.4 Altered mental status mental disorders Both 0.6982 0.991 0.945,1.04 1885 18096 0.3724 0.975 0.923,1.03 1390 13958
292.5 Transient alteration of awareness mental disorders Both 0.5929 0.969 0.865,1.09 327 3237 0.9817 1.0 0.883,1.14 263 2554
292.6 Hallucinations mental disorders Both 0.7586 1.03 0.868,1.21 144 1429 0.798 1.03 0.845,1.24 109 1130
293 Symptoms involving head and neck mental disorders Both 0.1455 1.09 0.97,1.23 304 3036 0.9954 1.0 0.961,1.04 2646 26528
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.3184 1.02 0.983,1.05 3691 32427 0.9954 1.0 0.961,1.04 2646 26528
295 Schizophrenia and other psychotic disorders mental disorders Both 0.4355 1.03 0.953,1.12 664 6564 0.695 0.979 0.88,1.09 383 4183
295.1 Schizophrenia mental disorders Both 0.2094 1.12 0.936,1.35 111 1080 0.2979 1.11 0.911,1.35 94 944
295.2 Paranoid disorders mental disorders Both 0.9638 1.0 0.808,1.25 86 856 0.6745 1.05 0.831,1.33 70 728
295.3 Psychosis mental disorders Both 0.6934 1.02 0.93,1.12 527 5206 0.695 0.979 0.88,1.09 383 4183
296 Mood disorders mental disorders Both 0.2223 1.01 0.991,1.04 12028 17942 0.6397 1.01 0.98,1.03 8917 15218
296.1 Bipolar mental disorders Both 0.1919 1.04 0.978,1.12 994 9331 0.1161 1.06 0.986,1.13 872 8271
296.2 Depression mental disorders Both 0.3715 1.01 0.987,1.04 11641 17941 0.6397 1.01 0.98,1.03 8917 15218
296.22 Major depressive disorder mental disorders Both 0.342 1.01 0.987,1.04 10773 17942 0.6397 1.01 0.98,1.03 8917 15218
297 Suicidal ideation or attempt mental disorders Both 0.8974 1.01 0.929,1.09 696 6932 0.7998 0.98 0.839,1.14 182 1804
297.1 Suicidal ideation mental disorders Both 0.4375 1.04 0.949,1.13 559 5575 0.618 1.02 0.933,1.12 499 4933
297.2 Suicide or self-inflicted injury mental disorders Both 0.3954 0.937 0.806,1.09 201 2010 0.7998 0.98 0.839,1.14 182 1804
300 Anxiety disorders mental disorders Both 0.2786 1.01 0.989,1.04 12038 17949 0.4613 0.967 0.884,1.06 543 5439
300.1 Anxiety disorder mental disorders Both 0.2023 1.02 0.992,1.04 11352 17942 0.3048 1.04 0.961,1.14 588 6231
300.11 Generalized anxiety disorder mental disorders Both 0.3236 1.02 0.983,1.05 4496 17788 0.3963 1.02 0.979,1.05 3691 15081
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.4764 1.02 0.958,1.1 957 9152 0.5649 1.02 0.951,1.1 845 8054
300.13 Phobia mental disorders Both 0.02951 1.09 1.01,1.17 731 7231 0.3048 1.04 0.961,1.14 588 6231
300.3 Obsessive-compulsive disorders mental disorders Both 0.955 1.0 0.875,1.15 223 2230 0.5848 1.04 0.9,1.21 189 1981
300.4 Dysthymic disorder mental disorders Both 0.5023 1.02 0.968,1.07 1798 13630 0.6353 1.01 0.96,1.07 1461 11676
300.8 Acute reaction to stress mental disorders Both 0.235 1.07 0.958,1.19 359 3536 0.4276 0.952 0.844,1.07 296 3085
300.9 Posttraumatic stress disorder mental disorders Both 0.6683 0.982 0.902,1.07 612 6113 0.4613 0.967 0.884,1.06 543 5439
301 Personality disorders mental disorders Both 0.7464 1.02 0.913,1.14 363 3626 0.7798 0.978 0.838,1.14 173 1694
301.2 Antisocial/borderline personality disorder mental disorders Both 0.618 0.962 0.827,1.12 187 1868 0.7798 0.978 0.838,1.14 173 1694
302 Sexual and gender identity disorders mental disorders Both 0.3396 0.959 0.881,1.04 608 6055 0.03388 0.87 0.765,0.989 264 2725
302.1 Decreased libido mental disorders Both 0.157 0.92 0.819,1.03 325 3233 0.03388 0.87 0.765,0.989 264 2725
303 Psychogenic and somatoform disorders mental disorders Both 0.1099 1.05 0.988,1.12 1030 10064 0.05495 1.07 0.998,1.15 788 7992
303.1 Dissociative disorder mental disorders Both 0.4688 1.07 0.89,1.29 115 1144 0.2858 1.11 0.914,1.35 94 991
303.3 Psychogenic disorder mental disorders Both 0.2877 1.04 0.966,1.12 736 7330 0.2432 1.07 0.952,1.21 277 2901
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.07079 1.11 0.991,1.23 340 3376 0.2432 1.07 0.952,1.21 277 2901
303.4 Somatoform disorder mental disorders Both 0.05495 1.07 0.998,1.14 925 9106 0.05495 1.07 0.998,1.15 788 7992
304 Adjustment reaction mental disorders Both 0.7161 1.01 0.968,1.05 2840 17464 0.7516 0.993 0.95,1.04 2332 14758
305.2 Eating disorder mental disorders Both 0.7129 0.985 0.908,1.07 650 6500 0.7998 0.989 0.908,1.08 574 5772
306 Other mental disorder mental disorders Both 0.7816 1.01 0.951,1.07 1254 10907 0.8551 1.01 0.916,1.11 445 4613
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.863 0.991 0.893,1.1 418 2847 0.6442 0.975 0.878,1.08 398 2662
306.9 Tension headache mental disorders Both 0.8933 0.994 0.908,1.09 521 5210 0.8551 1.01 0.916,1.11 445 4613
312 Conduct disorders mental disorders Both 9.12E-4 0.766 0.655,0.897 189 1890 0.001995 0.766 0.646,0.907 159 1593
312.3 Impulse control disorder mental disorders Both 0.003236 0.624 0.455,0.854 53 530 ,
313 Pervasive developmental disorders mental disorders Both 0.6855 0.987 0.928,1.05 1148 11078 0.1959 0.956 0.892,1.02 923 8870
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.4416 0.975 0.913,1.04 1012 9899 0.1959 0.956 0.892,1.02 923 8870
313.2 Tics and stuttering mental disorders Both 0.4305 0.898 0.687,1.17 60 593 ,
315 Develomental delays and disorders mental disorders Both 0.07586 1.1 0.991,1.21 401 3990 0.05012 1.19 1.0,1.41 137 1443
315.1 Learning disorder mental disorders Both 0.9333 1.01 0.778,1.31 60 599 0.7745 1.04 0.79,1.37 55 529
315.2 Speech and language disorder mental disorders Both 0.04786 1.16 1.0,1.35 182 1801 0.05012 1.19 1.0,1.41 137 1443
316 Substance addiction and disorders mental disorders Both 0.1738 1.03 0.988,1.07 2799 26014 0.1355 1.08 0.977,1.19 412 4153
316.1 Polyneuropathy due to drugs mental disorders Both 0.07079 1.08 0.993,1.18 518 5180 0.1355 1.08 0.977,1.19 412 4153
317 Alcohol-related disorders mental disorders Both 0.1014 0.961 0.917,1.01 1948 17547 0.6668 1.03 0.907,1.17 269 2588
317.1 Alcoholism mental disorders Both 0.06761 0.951 0.901,1.0 1517 14733 0.6668 1.03 0.907,1.17 269 2588
317.11 Alcoholic liver damage mental disorders Both 0.5888 0.969 0.866,1.09 335 3336 0.6668 1.03 0.907,1.17 269 2588
318 Tobacco use disorder mental disorders Both 0.6887 1.0 0.981,1.03 9473 26924 0.1148 1.02 0.995,1.05 7633 21981
320 Meningitis neurological Both 0.695 0.977 0.87,1.1 319 3181 0.5346 0.959 0.839,1.1 236 2634
323 Encephalitis neurological Both 0.2523 0.906 0.766,1.07 148 1475 0.0871 0.837 0.681,1.03 102 1035
323.8 Encephalitis, non-infectious neurological Both 0.04467 0.827 0.687,0.995 125 1245 0.0871 0.837 0.681,1.03 102 1035
324 Other CNS infection and poliomyelitis neurological Both 0.7178 0.976 0.853,1.12 245 2440 0.5058 0.949 0.815,1.11 186 1869
327 Sleep disorders neurological Both 0.5093 1.01 0.985,1.03 11517 26652 0.7464 1.01 0.947,1.08 991 9602
327.1 Hypersomnia neurological Both 4.677E-4 0.905 0.855,0.957 1403 13919 0.007413 0.92 0.865,0.978 1167 11357
327.3 Sleep apnea neurological Both 0.8128 1.0 0.978,1.03 8293 26193 0.4477 1.01 0.981,1.04 5312 20746
327.31 Central/nonobstroctive sleep apnea neurological Both 0.6823 0.977 0.872,1.09 326 3234 0.7228 0.977 0.859,1.11 255 2479
327.32 Obstructive sleep apnea neurological Both 0.869 1.0 0.975,1.03 6534 25537 0.4477 1.01 0.981,1.04 5312 20746
327.4 Insomnia neurological Both 0.3899 1.01 0.982,1.05 4197 25860 0.4426 0.97 0.896,1.05 693 7012
327.41 Organic or persistent insomnia neurological Both 0.3243 0.965 0.9,1.04 881 8743 0.4426 0.97 0.896,1.05 693 7012
327.5 Parasomnia neurological Both 0.9931 1.0 0.908,1.1 459 4583 0.9311 1.0 0.901,1.12 363 3551
327.6 Circadian rhythm sleep disorder neurological Both 0.912 1.01 0.862,1.18 174 1738 0.912 0.99 0.832,1.18 143 1463
327.7 Sleep related movement disorders neurological Both 0.5035 1.02 0.964,1.08 1364 13620 0.7464 1.01 0.947,1.08 991 9602
327.71 Restless legs syndrome neurological Both 0.9354 1.0 0.946,1.06 1214 12132 0.7464 1.01 0.947,1.08 991 9602
327.72 Sleep related leg cramps neurological Both 0.3412 1.13 0.876,1.47 55 550 ,
331 Other cerebral degenerations neurological Both 0.9931 1.0 0.92,1.09 602 5935 0.3499 1.06 0.934,1.21 232 2401
331.1 Hydrocephalus neurological Both 0.7362 0.978 0.857,1.11 246 2447 0.5521 1.04 0.907,1.2 208 2011
331.9 Cerebral degeneration, unspecified neurological Both 0.6295 1.03 0.923,1.14 349 3423 0.3499 1.06 0.934,1.21 232 2401
332 Parkinson's disease neurological Both 0.4426 0.956 0.851,1.07 333 3321 0.3565 0.937 0.817,1.08 245 2344
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.6683 1.01 0.966,1.05 2169 20920 0.1858 1.1 0.955,1.27 201 2129
333.1 Essential tremor neurological Both 0.9016 1.01 0.922,1.1 551 5488 0.3443 0.951 0.857,1.06 399 4088
333.2 Myoclonus neurological Both 0.2818 0.901 0.746,1.09 117 1160 0.4102 0.917 0.747,1.13 96 943
333.4 Torsion dystonia neurological Both 0.1892 1.09 0.96,1.23 266 2646 0.1858 1.1 0.955,1.27 201 2129
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.9484 0.992 0.776,1.27 64 640 ,
334 Degenerative disease of the spinal cord neurological Both 0.8831 1.01 0.938,1.08 874 8734 0.4989 0.92 0.722,1.17 71 711
334.1 Spinocerebellar disease neurological Both 0.6653 1.06 0.818,1.37 64 631 0.5508 1.09 0.821,1.45 51 488
334.2 Anterior horn cell disease neurological Both 0.8551 0.981 0.796,1.21 92 920 0.4989 0.92 0.722,1.17 71 711
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.5188 1.09 0.84,1.41 57 570 ,
335 Multiple sclerosis neurological Both 0.826 1.01 0.904,1.13 330 3284 0.7295 0.978 0.86,1.11 264 2750
337 Disorders of the autonomic nervous system neurological Both 0.695 0.982 0.898,1.07 528 5257 0.5741 0.948 0.788,1.14 126 1424
337.1 Peripheral autonomic neuropathy neurological Both 0.561 0.955 0.819,1.11 185 1837 0.5741 0.948 0.788,1.14 126 1424
338 Pain neurological Both 0.3251 0.99 0.97,1.01 16189 22165 0.9333 0.999 0.971,1.03 6782 17898
338.1 Acute pain neurological Both 0.2228 0.986 0.965,1.01 12567 22166 0.9572 1.0 0.977,1.03 10322 17909
338.2 Chronic pain neurological Both 0.2138 0.984 0.959,1.01 8223 22154 0.9333 0.999 0.971,1.03 6782 17898
339 Other headache syndromes neurological Both 0.9247 0.999 0.974,1.02 8578 27793 0.6887 0.994 0.968,1.02 7191 22406
340 Migraine neurological Both 0.6531 0.993 0.963,1.02 5377 24263 0.8974 1.0 0.961,1.05 2412 15464
340.1 Migrain with aura neurological Both 0.9954 1.0 0.961,1.04 2862 18665 0.8974 1.0 0.961,1.05 2412 15464
341 Other demyelinating diseases of central nervous system neurological Both 0.7278 1.03 0.854,1.25 111 1105 0.7047 0.957 0.761,1.2 81 933
342 Hemiplegia neurological Both 0.4083 1.05 0.94,1.16 360 3589 0.1 1.11 0.981,1.25 287 2844
343 Infantile cerebral palsy neurological Both 0.1483 1.19 0.94,1.5 75 750 0.3119 1.14 0.888,1.45 68 677
344 Other paralytic syndromes neurological Both 0.5888 0.976 0.895,1.06 564 5640 0.8279 0.989 0.898,1.09 443 4560
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.3177 0.977 0.934,1.02 2084 20790 0.5728 0.985 0.936,1.04 1636 16259
345.1 Epilepsy neurological Both 0.5346 0.974 0.896,1.06 607 6053 0.4436 0.958 0.859,1.07 361 3634
345.11 Generalized convulsive epilepsy neurological Both 0.4581 0.946 0.818,1.09 196 1960 0.3443 0.926 0.789,1.09 163 1708
345.12 Partial epilepsy neurological Both 0.4742 0.964 0.873,1.07 434 4333 0.4436 0.958 0.859,1.07 361 3634
345.3 Convulsions neurological Both 0.3443 0.978 0.933,1.02 1967 19598 0.5728 0.985 0.936,1.04 1636 16259
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.7396 1.03 0.87,1.22 142 1404 0.8511 1.02 0.809,1.29 72 725
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.3412 1.03 0.97,1.09 1196 11927 0.7244 1.01 0.945,1.09 865 9355
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.526 0.933 0.753,1.16 87 860 0.3524 0.886 0.687,1.14 60 683
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.5117 1.07 0.868,1.33 90 884 0.8511 1.02 0.809,1.29 72 725
347 Cataplexy and narcolepsy neurological Both 0.7852 1.03 0.81,1.32 67 670 0.5236 1.09 0.844,1.4 62 583
348 Other conditions of brain neurological Both 0.3404 0.974 0.922,1.03 1424 14226 0.9141 1.0 0.952,1.06 1521 16093
348.2 Cerebral edema and compression of brain neurological Both 0.4018 0.969 0.899,1.04 747 7463 0.3784 0.963 0.886,1.05 595 6189
348.4 Cerebral cysts neurological Both 0.1923 0.905 0.78,1.05 195 1945 0.07586 0.861 0.731,1.02 163 1638
348.7 Coma neurological Both 0.09333 0.867 0.734,1.02 162 1620 0.1754 0.884 0.739,1.06 138 1328
348.8 Encephalopathy, not elsewhere classified neurological Both 0.6486 1.02 0.94,1.11 636 6331 0.4477 1.04 0.945,1.14 483 4842
348.9 Other conditions of brain, NOS neurological Both 0.6109 1.01 0.967,1.06 2001 19979 0.9141 1.0 0.952,1.06 1521 16093
349 Other and unspecified disorders of the nervous system neurological Both 0.3184 0.963 0.893,1.04 775 7750 0.4046 0.965 0.888,1.05 625 6270
350 Abnormal movement neurological Both 0.8204 1.0 0.974,1.03 5109 32314 0.1991 0.924 0.818,1.04 285 3541
350.1 Abnormal involuntary movements neurological Both 0.955 0.999 0.958,1.04 2464 24243 0.4121 0.98 0.935,1.03 1883 19381
350.2 Abnormality of gait neurological Both 0.3451 0.982 0.945,1.02 2979 25007 0.1 0.964 0.922,1.01 2237 19825
350.3 Lack of coordination neurological Both 0.1549 1.06 0.98,1.14 773 7693 0.1841 1.06 0.973,1.15 590 6206
350.5 Abnormal reflex neurological Both 0.3236 0.915 0.767,1.09 143 1430 0.1618 0.869 0.714,1.06 118 1190
350.6 Disturbances of sensation of smell and taste neurological Both 0.3436 0.954 0.866,1.05 448 4480 0.1991 0.924 0.818,1.04 285 3541
351 Other peripheral nerve disorders neurological Both 0.3954 0.988 0.96,1.02 5685 28844 0.6124 0.992 0.961,1.02 4569 23488
352 Disorders of other cranial nerves neurological Both 0.6368 1.01 0.96,1.07 1412 14120 0.6053 1.03 0.933,1.13 451 5071
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.9016 0.994 0.902,1.09 440 4393 0.5689 0.969 0.869,1.08 348 3544
352.2 Facial nerve disorders [CN7] neurological Both 0.743 1.01 0.935,1.1 640 6400 0.6053 1.03 0.933,1.13 451 5071
353 Nerve root and plexus disorders neurological Both 0.6714 0.992 0.957,1.03 3295 28097 0.6339 0.945 0.748,1.19 76 728
353.1 Nerve plexus lesions neurological Both 0.7079 0.977 0.868,1.1 308 3077 0.6252 0.969 0.852,1.1 265 2626
353.2 Nerve root lesions neurological Both 0.9162 0.989 0.803,1.22 94 930 0.6339 0.945 0.748,1.19 76 728
355 Complex regional/central pain syndrome neurological Both 0.9376 1.0 0.909,1.11 419 4170 0.5176 0.971 0.887,1.06 544 5370
355.1 Chronic pain syndrome neurological Both 0.867 0.993 0.915,1.08 654 6509 0.5176 0.971 0.887,1.06 544 5370
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.2541 0.972 0.925,1.02 1728 17176 0.1888 0.962 0.909,1.02 1300 13214
357 Inflammatory and toxic neuropathy neurological Both 0.1837 0.972 0.932,1.01 2467 24091 0.01479 0.941 0.897,0.988 1854 18723
358 Myoneural disorders neurological Both 0.7852 1.01 0.941,1.08 845 8441 0.2393 1.15 0.909,1.47 68 670
358.1 Myasthenia gravis neurological Both 0.3556 1.11 0.89,1.38 85 850 0.2393 1.15 0.909,1.47 68 670
359 Muscular dystrophies and other myopathies neurological Both 0.1538 0.95 0.885,1.02 868 8655 0.03548 0.917 0.845,0.994 663 6642
359.1 Muscular dystrophies neurological Both 0.5728 0.92 0.688,1.23 52 520 ,
359.2 Myopathy neurological Both 0.2032 0.954 0.888,1.03 833 8306 0.03548 0.917 0.845,0.994 663 6642
360 Disorders of the globe sense organs Both 0.929 1.01 0.829,1.23 102 1013 0.8974 1.02 0.799,1.29 71 792
361 Retinal detachments and defects sense organs Both 0.335 1.04 0.956,1.14 528 5265 0.09772 1.14 0.976,1.34 161 1671
361.1 Retinal detachment with retinal defect sense organs Both 0.2618 1.08 0.944,1.24 225 2226 0.09772 1.14 0.976,1.34 161 1671
362 Other retinal disorders sense organs Both 0.3027 0.978 0.938,1.02 2489 18838 0.00955 0.79 0.661,0.944 144 1484
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.3981 0.977 0.927,1.03 1529 12328 0.01549 0.915 0.852,0.983 854 7974
362.21 Macular degeneration, dry sense organs Both 0.6281 1.03 0.918,1.15 313 2650 0.561 0.956 0.821,1.11 178 1779
362.22 Macular degeneration, wet sense organs Both 0.4875 0.935 0.773,1.13 108 881 0.7943 0.968 0.759,1.23 69 555
362.23 Cystoid macular degeneration of retina sense organs Both 0.1556 0.915 0.81,1.03 285 2777 0.1384 0.895 0.774,1.04 202 2025
362.26 Macular puckering of retina sense organs Both 0.01862 0.906 0.835,0.984 645 6254 3.467E-4 0.83 0.75,0.919 441 4507
362.27 Drusen (degenerative) of retina sense organs Both 0.5808 0.969 0.866,1.08 335 3205 0.826 0.984 0.855,1.13 210 2323
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.1652 0.96 0.907,1.02 1323 10928 0.01549 0.915 0.852,0.983 854 7974
362.3 Other nondiabetic retinopathy sense organs Both 0.5546 0.976 0.901,1.06 653 6476 0.2291 1.09 0.948,1.25 212 2232
362.31 Separation of retinal layers sense organs Both 0.1079 1.1 0.979,1.24 296 2938 0.2291 1.09 0.948,1.25 212 2232
362.4 Retinal vascular changes and abnomalities sense organs Both 0.955 1.0 0.911,1.1 449 4295 0.7889 1.02 0.908,1.14 328 3099
362.6 Peripheral retinal degenerations sense organs Both 0.1047 0.898 0.788,1.02 262 2600 0.2223 0.912 0.786,1.06 198 2018
362.7 Hereditary retinal dystrophies sense organs Both 0.1901 0.886 0.739,1.06 124 1233 0.0871 0.824 0.66,1.03 83 956
362.8 Retinal hemorrhage/ischemia sense organs Both 0.02042 0.82 0.693,0.97 160 1570 0.01862 0.791 0.651,0.962 123 1168
362.9 Retinal edema sense organs Both 0.4753 0.95 0.824,1.09 202 2001 0.00955 0.79 0.661,0.944 144 1484
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.8072 1.01 0.914,1.12 375 3665 0.7889 0.979 0.842,1.14 178 1788
363.3 Chorioretinal scars sense organs Both 0.6531 1.03 0.906,1.17 249 2430 0.7889 0.979 0.842,1.14 178 1788
364 Corneal opacity and other disorders of cornea sense organs Both 0.8954 0.995 0.926,1.07 809 7919 0.7244 0.949 0.712,1.27 54 515
364.1 Corneal opacity sense organs Both 0.875 0.991 0.879,1.12 294 2930 0.975 1.0 0.877,1.15 234 2348
364.2 Corneal edema sense organs Both 0.7161 0.961 0.775,1.19 84 819 0.4276 0.904 0.704,1.16 65 660
364.4 Corneal degenerations sense organs Both 0.7551 0.981 0.868,1.11 274 2719 0.547 0.956 0.826,1.11 198 2125
364.5 Corneal dystrophy sense organs Both 0.561 1.03 0.93,1.14 377 3673 0.7129 1.03 0.869,1.23 134 1470
364.51 Fuchs' dystrophy sense organs Both 0.5649 1.04 0.907,1.2 207 2008 0.7129 1.03 0.869,1.23 134 1470
364.9 Cornea replaced by transplant sense organs Both 0.7015 0.952 0.743,1.22 69 677 0.7244 0.949 0.712,1.27 54 515
365 Glaucoma sense organs Both 0.5297 1.01 0.969,1.06 1986 17152 0.5321 0.941 0.777,1.14 116 1276
365.1 Open-angle glaucoma sense organs Both 0.2972 0.954 0.872,1.04 523 4963 0.02692 0.839 0.718,0.98 184 1822
365.11 Primary open angle glaucoma sense organs Both 0.2723 0.934 0.826,1.06 281 2609 0.02692 0.839 0.718,0.98 184 1822
365.2 Primary angle-closure glaucoma sense organs Both 0.8453 0.985 0.846,1.15 179 1707 0.5321 0.941 0.777,1.14 116 1276
366 Cataract sense organs Both 0.5117 0.99 0.962,1.02 6335 23476 0.1057 0.966 0.926,1.01 2635 16029
366.1 Nonsenile Cataract sense organs Both 0.6252 1.04 0.887,1.22 163 1622 0.1888 1.13 0.94,1.37 116 1225
366.2 Senile cataract sense organs Both 0.2455 0.979 0.945,1.01 3827 20410 0.1057 0.966 0.926,1.01 2635 16029
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.3698 0.988 0.962,1.01 6553 31745 0.6383 1.02 0.945,1.1 736 7528
367.1 Myopia sense organs Both 0.3396 0.983 0.949,1.02 3578 28818 0.8017 0.995 0.957,1.03 2868 23722
367.2 Astigmatism sense organs Both 0.7145 0.993 0.955,1.03 2892 26106 0.3648 1.02 0.977,1.07 2251 21168
367.4 Presbyopia sense organs Both 0.1371 0.973 0.938,1.01 3297 24582 0.2553 0.976 0.935,1.02 2441 19359
367.8 Hypermetropia sense organs Both 0.09333 0.955 0.906,1.01 1504 14729 0.1148 0.951 0.893,1.01 1092 11517
367.9 Blindness and low vision sense organs Both 0.8318 1.01 0.944,1.07 976 9663 0.6383 1.02 0.945,1.1 736 7528
368 Visual disturbances sense organs Both 0.6053 0.992 0.96,1.02 4287 32818 0.863 1.02 0.795,1.31 67 649
368.1 Amblyopia sense organs Both 0.4624 0.965 0.879,1.06 484 4830 0.5458 0.968 0.871,1.08 382 3882
368.2 Diplopia and disorders of binocular vision sense organs Both 0.547 1.02 0.952,1.1 822 8186 0.929 1.0 0.925,1.09 633 6450
368.3 Anisometropia sense organs Both 0.537 0.95 0.806,1.12 166 1648 0.7889 0.975 0.807,1.18 126 1332
368.4 Visual field defects sense organs Both 0.7482 0.989 0.923,1.06 879 8777 0.3981 0.966 0.891,1.05 649 6710
368.9 Subjective visual disturbances sense organs Both 0.04677 0.93 0.865,0.999 829 8268 0.863 1.02 0.795,1.31 67 649
368.91 Psychophysical visual disturbances sense organs Both 0.5794 1.06 0.855,1.32 89 885 0.863 1.02 0.795,1.31 67 649
369 Infection of the eye sense organs Both 0.6295 1.01 0.968,1.05 2328 22262 0.7129 0.99 0.941,1.04 1611 16285
369.2 Eye infection, viral sense organs Both 0.08128 1.1 0.988,1.21 372 3688 0.3614 1.06 0.94,1.18 299 3066
369.5 Conjunctivitis, infectious sense organs Both 0.9705 0.999 0.954,1.05 1974 19408 0.7129 0.99 0.941,1.04 1611 16285
370 Keratitis sense organs Both 0.9817 0.999 0.938,1.06 1051 10280 0.9141 1.01 0.823,1.24 99 1114
370.1 Corneal ulcer sense organs Both 0.6577 1.04 0.886,1.21 164 1630 0.7852 1.02 0.863,1.22 132 1343
370.2 Superficial keratitis sense organs Both 0.9863 1.0 0.904,1.11 394 3916 0.52 0.96 0.848,1.09 266 3082
370.3 Keratoconjunctivitis sense organs Both 0.6561 1.02 0.933,1.12 531 5159 0.9141 1.01 0.823,1.24 99 1114
370.31 Keratoconjunctivitis sicca sense organs Both 0.2931 1.09 0.926,1.29 150 1432 0.9141 1.01 0.823,1.24 99 1114
371 Inflammation of the eye sense organs Both 0.4416 0.986 0.95,1.02 3269 26161 0.3451 1.11 0.889,1.4 76 805
371.1 Uveitis, noninfectious or NOS sense organs Both 0.007079 0.867 0.781,0.962 394 3892 0.01479 0.86 0.762,0.971 287 3083
371.2 Conjunctivitis, noninfectious sense organs Both 0.9036 0.995 0.919,1.08 651 6462 0.2594 0.945 0.856,1.04 439 4367
371.21 Allergic conjunctivitis sense organs Both 0.9616 0.998 0.913,1.09 532 5279 0.2594 0.945 0.856,1.04 439 4367
371.3 Inflammation of eyelids sense organs Both 0.7834 0.994 0.954,1.04 2523 21781 0.3451 1.11 0.889,1.4 76 805
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.1652 1.15 0.943,1.41 100 979 0.3451 1.11 0.889,1.4 76 805
372 Disorders of conjunctiva sense organs Both 0.2307 1.04 0.973,1.12 827 8153 0.5433 1.03 0.943,1.12 558 6310
374 Other disorders of eyelids sense organs Both 0.6295 0.989 0.945,1.03 2093 18512 0.07762 0.918 0.834,1.01 481 5455
374.1 Ectropion or entropion sense organs Both 0.1995 1.07 0.963,1.2 337 3251 0.7311 1.03 0.88,1.2 169 2337
374.2 Lagophthalmos sense organs Both 0.5875 0.959 0.826,1.11 192 1900 0.3819 0.917 0.756,1.11 113 1523
374.3 Ptosis of eyelid sense organs Both 0.3334 0.965 0.897,1.04 817 8140 0.08318 0.924 0.846,1.01 554 6161
374.6 Dermatochalasis sense organs Both 0.1766 0.949 0.88,1.02 759 7426 0.07762 0.918 0.834,1.01 481 5455
375 Disorders of lacrimal system sense organs Both 0.1698 0.972 0.934,1.01 2683 21054 0.1469 0.903 0.787,1.04 231 2712
375.1 Dry eyes sense organs Both 0.2296 0.977 0.94,1.02 2966 21823 0.1875 0.97 0.927,1.01 2155 17380
375.2 Epiphora sense organs Both 0.5212 0.965 0.865,1.08 356 3540 0.1469 0.903 0.787,1.04 231 2712
376 Disorders of the orbit sense organs Both 0.04074 0.879 0.777,0.994 285 2814 0.1107 0.892 0.776,1.03 220 2359
377 Disorders of optic nerve and visual pathways sense organs Both 0.009333 0.9 0.832,0.974 706 7010 0.01778 0.877 0.787,0.978 382 3778
377.1 Optic atrophy sense organs Both 0.8892 1.01 0.876,1.17 200 1997 0.7798 1.02 0.866,1.21 145 1595
377.3 Optic neuritis/neuropathy sense organs Both 7.079E-4 0.844 0.766,0.931 468 4627 0.01778 0.877 0.787,0.978 382 3778
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.9817 1.0 0.937,1.07 969 9602 0.3243 1.07 0.933,1.23 214 2200
378.1 Strabismus (not specified as paralytic) sense organs Both 0.9954 1.0 0.921,1.09 617 6131 0.8414 0.99 0.902,1.09 485 4929
378.2 Nystagmus and other irregular eye movements sense organs Both 0.8933 1.01 0.851,1.2 138 1371 0.5585 1.06 0.879,1.27 123 1136
378.5 Paralytic strabismus sense organs Both 0.2249 1.08 0.954,1.22 275 2720 0.3243 1.07 0.933,1.23 214 2200
379 Other disorders of eye sense organs Both 0.9683 0.999 0.965,1.04 3593 24835 0.3707 0.965 0.892,1.04 685 7157
379.1 Scleritis and episcleritis sense organs Both 0.8492 0.984 0.83,1.17 140 1379 0.6138 0.951 0.782,1.16 108 1161
379.2 Disorders of vitreous body sense organs Both 0.3802 0.982 0.942,1.02 2559 18709 0.6471 0.988 0.94,1.04 1747 14403
379.3 Aphakia and other disorders of lens sense organs Both 0.3963 1.1 0.887,1.35 87 838 0.6982 0.949 0.728,1.24 59 629
379.4 Anomalies of pupillary function sense organs Both 0.2735 1.08 0.944,1.23 231 2303 0.03802 1.17 1.01,1.36 176 1855
379.5 Disorders of iris and ciliary body sense organs Both 0.9795 0.998 0.87,1.14 215 2128 0.8222 1.02 0.87,1.19 162 1656
379.51 Pigmentary iris degeneration sense organs Both 0.6427 0.942 0.733,1.21 61 610 ,
379.9 Pain, swelling or discharge of eye sense organs Both 0.4036 0.971 0.905,1.04 870 8594 0.3707 0.965 0.892,1.04 685 7157
380 Disorders of external ear sense organs Both 0.8337 0.995 0.945,1.05 1634 15553 0.2649 0.969 0.917,1.02 1398 14538
380.1 Otitis externa sense organs Both 0.2742 0.966 0.908,1.03 1124 11213 0.07079 0.938 0.874,1.01 891 9185
380.4 Impacted cerumen sense organs Both 0.787 0.994 0.949,1.04 1985 18630 0.2649 0.969 0.917,1.02 1398 14538
381 Otitis media and Eustachian tube disorders sense organs Both 0.5984 1.01 0.974,1.05 3291 29339 0.0631 1.13 0.993,1.29 230 2410
381.1 Otitis media sense organs Both 0.955 0.999 0.958,1.04 2402 23549 0.9183 0.997 0.949,1.05 1726 17115
381.11 Suppurative and unspecified otitis media sense organs Both 0.8511 1.0 0.96,1.05 2037 20175 0.9183 0.997 0.949,1.05 1726 17115
381.2 Eustachian tube disorders sense organs Both 0.673 1.01 0.958,1.07 1393 13815 0.6095 1.02 0.956,1.08 1102 11529
381.3 Mastoiditis & related conditions sense organs Both 0.1611 0.875 0.727,1.05 126 1260 0.3228 0.904 0.74,1.1 107 1062
381.9 Otorrhea sense organs Both 0.1271 1.1 0.974,1.23 297 2960 0.0631 1.13 0.993,1.29 230 2410
382 Otalgia sense organs Both 0.8147 0.993 0.941,1.05 1425 14188 0.2944 0.968 0.911,1.03 1153 11878
383 Otosclerosis sense organs Both 0.9311 1.01 0.832,1.22 112 1120 0.8166 1.03 0.831,1.26 96 925
384 Other disorders of tympanic membrane sense organs Both 0.5 0.965 0.87,1.07 397 3962 0.6039 0.967 0.852,1.1 264 2667
384.4 Perforation of tympanic membrane sense organs Both 0.3776 0.949 0.845,1.07 318 3180 0.6039 0.967 0.852,1.1 264 2667
385 Other disorders of middle ear and mastoid sense organs Both 0.4236 0.956 0.857,1.07 358 3580 0.4624 0.923 0.744,1.14 90 877
385.3 Cholesteatoma sense organs Both 0.2673 0.929 0.815,1.06 245 2450 0.3083 0.93 0.808,1.07 212 2108
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.3214 0.904 0.741,1.1 103 1025 0.4624 0.923 0.744,1.14 90 877
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.9419 1.0 0.95,1.06 1441 14255 0.5689 0.99 0.958,1.02 4157 25776
386.1 Meniere's disease sense organs Both 0.867 1.01 0.886,1.15 248 2464 0.4508 1.06 0.914,1.23 194 1977
386.2 Peripheral or central vertigo sense organs Both 0.6823 1.01 0.955,1.07 1209 11971 0.8185 0.991 0.916,1.07 677 6922
386.21 Central origin vertigo sense organs Both 0.6653 0.985 0.919,1.06 883 8759 0.8185 0.991 0.916,1.07 677 6922
386.3 Labyrinthitis sense organs Both 0.5433 0.981 0.923,1.04 1099 10904 0.9795 0.999 0.932,1.07 858 8697
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.975 1.0 0.971,1.03 5315 31605 0.5689 0.99 0.958,1.02 4157 25776
388 Other disorders of ear sense organs Both 0.9441 1.0 0.928,1.08 699 6960 0.4345 1.04 0.948,1.13 540 5743
389 Hearing loss sense organs Both 0.8222 1.0 0.976,1.03 6285 31750 0.798 0.97 0.77,1.22 80 840
389.1 Sensorineural hearing loss sense organs Both 0.7261 1.01 0.97,1.04 3130 24231 0.4487 0.983 0.941,1.03 2239 19460
389.2 Conductive hearing loss sense organs Both 0.4436 1.03 0.955,1.11 717 7169 0.4406 1.03 0.951,1.12 612 6130
389.3 Degenerative and vascular disorders of ear sense organs Both 0.6823 1.04 0.871,1.23 143 1338 0.3428 0.902 0.729,1.12 99 997
389.4 Tinnitus sense organs Both 0.3981 1.02 0.972,1.07 1677 16701 0.7145 1.01 0.954,1.07 1250 13371
389.5 Disorders of acoustic nerve sense organs Both 0.3954 0.914 0.743,1.12 101 1010 0.798 0.97 0.77,1.22 80 840
394 Rheumatic disease of the heart valves circulatory system Both 0.7499 1.01 0.952,1.07 1177 11253 0.2642 1.06 0.956,1.18 362 3394
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.9594 0.997 0.884,1.12 284 2766 0.787 0.981 0.85,1.13 201 1998
394.2 Mitral valve disease circulatory system Both 0.9931 1.0 0.901,1.11 378 3735 0.4345 1.05 0.93,1.19 277 2734
394.3 Aortic valve disease circulatory system Both 0.7396 0.972 0.82,1.15 150 1465 0.6887 1.04 0.856,1.26 116 1037
394.7 Disease of tricuspid valve circulatory system Both 0.798 1.01 0.923,1.11 468 4624 0.2642 1.06 0.956,1.18 362 3394
395 Heart valve disorders circulatory system Both 0.5483 1.01 0.975,1.05 3169 23926 0.4198 1.03 0.954,1.12 666 5958
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.4236 1.02 0.972,1.07 1754 16787 0.02754 1.06 1.01,1.13 1334 12948
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.6039 1.01 0.963,1.07 1619 13932 0.413 1.03 0.966,1.09 1199 10314
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.7551 0.984 0.887,1.09 373 3704 0.7907 1.02 0.901,1.15 277 2739
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.4831 1.08 0.87,1.34 84 831 0.3802 1.11 0.879,1.4 71 698
395.6 Heart valve replaced circulatory system Both 0.6109 1.02 0.95,1.09 878 8213 0.4198 1.03 0.954,1.12 666 5958
396 Abnormal heart sounds circulatory system Both 0.695 1.01 0.973,1.04 3754 28453 0.798 1.01 0.967,1.04 2873 22952
401 Hypertension circulatory system Both 0.005012 1.03 1.01,1.06 18784 19071 0.5715 1.02 0.962,1.07 1517 10686
401.1 Essential hypertension circulatory system Both 0.006761 1.03 1.01,1.06 18655 19070 0.0263 1.03 1.0,1.06 14298 16443
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.02818 1.05 1.01,1.1 2599 12045 0.4808 1.02 0.964,1.08 1484 8833
401.21 Hypertensive heart disease circulatory system Both 0.0182 1.11 1.02,1.22 556 4628 0.01148 1.14 1.03,1.27 404 3539
401.22 Hypertensive chronic kidney disease circulatory system Both 0.1172 1.04 0.99,1.09 2015 10909 0.4808 1.02 0.964,1.08 1484 8833
401.3 Other hypertensive complications circulatory system Both 0.138 1.04 0.988,1.09 2027 12961 0.5715 1.02 0.962,1.07 1517 10686
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.0871 1.04 0.994,1.09 2132 15248 0.2793 1.03 0.977,1.08 1639 12783
411 Ischemic Heart Disease circulatory system Both 0.7261 0.995 0.968,1.02 6970 25468 0.4477 1.05 0.924,1.2 251 2342
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.7178 0.986 0.912,1.07 702 6842 0.5093 0.969 0.884,1.06 517 4963
411.2 Myocardial infarction circulatory system Both 0.2382 1.02 0.984,1.07 2849 17983 0.2023 1.03 0.984,1.08 2051 13892
411.3 Angina pectoris circulatory system Both 0.4571 1.02 0.971,1.07 1904 15218 0.5861 1.02 0.961,1.07 1414 11570
411.4 Coronary atherosclerosis circulatory system Both 0.455 0.989 0.959,1.02 5938 22890 0.2679 0.881 0.705,1.1 87 869
411.41 Aneurysm and dissection of heart circulatory system Both 0.1094 0.857 0.709,1.04 117 1149 0.2679 0.881 0.705,1.1 87 869
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.208 0.979 0.948,1.01 4877 21174 0.8433 0.996 0.959,1.03 3618 16642
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.5929 1.03 0.923,1.15 335 3247 0.4477 1.05 0.924,1.2 251 2342
414 Other forms of chronic heart disease circulatory system Both 0.8995 0.997 0.955,1.04 2360 18485 0.4764 1.04 0.934,1.16 359 3518
414.2 ASCVD circulatory system Both 0.955 1.0 0.915,1.1 492 4846 0.4764 1.04 0.934,1.16 359 3518
415 Pulmonary heart disease circulatory system Both 0.2143 0.975 0.937,1.01 2726 25061 0.5808 1.03 0.933,1.13 459 4449
415.1 Acute pulmonary heart disease circulatory system Both 0.5728 0.985 0.934,1.04 1510 15045 0.5188 0.98 0.923,1.04 1173 11647
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.5702 0.985 0.934,1.04 1507 15014 0.5188 0.98 0.923,1.04 1173 11647
415.2 Chronic pulmonary heart disease circulatory system Both 0.4842 0.981 0.931,1.03 1506 14839 0.5808 1.03 0.933,1.13 459 4449
415.21 Primary pulmonary hypertension circulatory system Both 0.9397 1.0 0.923,1.09 592 5901 0.5808 1.03 0.933,1.13 459 4449
416 Cardiomegaly circulatory system Both 0.4943 1.02 0.958,1.09 935 9293 0.3548 1.04 0.961,1.12 715 7040
418 Nonspecific chest pain circulatory system Both 0.7096 0.996 0.973,1.02 10015 28233 0.4009 1.03 0.962,1.1 900 9076
418.1 Precordial pain circulatory system Both 0.3631 1.03 0.969,1.09 1193 11816 0.4009 1.03 0.962,1.1 900 9076
420 Carditis circulatory system Both 0.3733 1.03 0.969,1.09 1275 12633 0.5623 1.03 0.935,1.13 455 4453
420.1 Myocarditis circulatory system Both 0.5433 1.07 0.851,1.36 76 752 0.8241 1.03 0.798,1.33 61 604
420.2 Pericarditis circulatory system Both 0.309 1.04 0.963,1.13 684 6830 0.2773 1.14 0.902,1.43 72 720
420.21 Acute pericarditis circulatory system Both 0.9462 0.994 0.837,1.18 144 1435 0.7586 1.03 0.851,1.25 116 1162
420.22 Chronic pericarditis circulatory system Both 0.1762 1.15 0.938,1.42 92 912 0.2773 1.14 0.902,1.43 72 720
420.3 Endocarditis circulatory system Both 0.5321 1.03 0.946,1.11 602 5990 0.5623 1.03 0.935,1.13 455 4453
425 Cardiomyopathy circulatory system Both 0.9572 0.999 0.949,1.05 1617 15758 0.06918 1.14 0.989,1.32 187 1969
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.8395 1.01 0.955,1.06 1557 15170 0.03388 1.22 1.02,1.46 121 1211
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.1416 1.12 0.962,1.31 171 1699 0.01202 1.25 1.05,1.49 133 1303
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.08318 1.15 0.982,1.35 154 1540 0.03388 1.22 1.02,1.46 121 1211
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.3412 1.07 0.935,1.21 248 2480 0.06918 1.14 0.989,1.32 187 1969
425.8 Other cardiomyopathy circulatory system Both 0.6745 0.95 0.746,1.21 71 709 ,
426 Cardiac conduction disorders circulatory system Both 0.9441 1.0 0.976,1.03 9881 21221 0.9078 0.994 0.905,1.09 489 4172
426.2 Atrioventricular [AV] block circulatory system Both 0.2911 1.03 0.975,1.09 1527 9610 0.1589 0.869 0.714,1.06 112 1034
426.21 First degree AV block circulatory system Both 0.2032 1.04 0.978,1.11 1064 7510 0.4121 1.03 0.957,1.11 766 5566
426.22 Mobitz II AV block circulatory system Both 0.8222 1.03 0.783,1.36 56 513 ,
426.23 Second degree AV block circulatory system Both 0.003388 1.26 1.08,1.48 161 1459 0.0182 1.26 1.04,1.52 113 991
426.24 Atrioventricular block, complete circulatory system Both 0.9528 0.997 0.895,1.11 357 3041 0.6839 0.974 0.856,1.11 258 2156
426.25 Other heart block circulatory system Both 0.1132 0.876 0.744,1.03 161 1489 0.1589 0.869 0.714,1.06 112 1034
426.3 Bundle branch block circulatory system Both 0.5152 0.983 0.935,1.03 1775 11373 0.7621 0.986 0.9,1.08 530 4556
426.31 Right bundle branch block circulatory system Both 0.4842 0.978 0.918,1.04 1101 8763 0.4159 0.97 0.9,1.04 797 6621
426.32 Left bundle branch block circulatory system Both 0.861 1.01 0.932,1.09 721 6217 0.7621 0.986 0.9,1.08 530 4556
426.4 Anomalous atrioventricular excitation circulatory system Both 0.875 1.02 0.792,1.32 62 611 0.7413 0.956 0.73,1.25 56 546
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.8299 1.0 0.977,1.03 8452 21094 0.6546 1.01 0.977,1.04 6492 17639
426.8 Other cardiac conduction disorders circulatory system Both 0.0912 1.08 0.987,1.19 456 4529 0.06166 1.11 0.995,1.23 347 3455
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.5082 1.02 0.961,1.08 1261 8802 0.9078 0.994 0.905,1.09 489 4172
426.91 Cardiac pacemaker in situ circulatory system Both 0.1384 1.06 0.983,1.13 836 6124 0.2924 1.05 0.961,1.14 590 4472
426.92 Cardiac defibrillator in situ circulatory system Both 0.7096 0.984 0.906,1.07 628 5698 0.9078 0.994 0.905,1.09 489 4172
427 Cardiac dysrhythmias circulatory system Both 0.9908 1.0 0.978,1.02 14018 21321 0.1371 1.03 0.99,1.07 2716 16745
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.7925 0.994 0.947,1.04 1882 14769 0.5984 1.02 0.943,1.11 669 6084
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.5821 0.983 0.927,1.04 1193 11216 0.241 0.961 0.898,1.03 940 8875
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.7311 0.988 0.921,1.06 892 7975 0.5984 1.02 0.943,1.11 669 6084
427.2 Atrial fibrillation and flutter circulatory system Both 0.7962 1.0 0.969,1.04 4194 15493 0.861 1.01 0.944,1.07 1187 7369
427.21 Atrial fibrillation circulatory system Both 0.9795 1.0 0.964,1.04 4097 15312 0.4688 1.02 0.973,1.06 2976 12217
427.22 Atrial flutter circulatory system Both 0.6501 1.01 0.959,1.07 1598 9674 0.861 1.01 0.944,1.07 1187 7369
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.929 0.999 0.971,1.03 7129 21276 0.9268 0.999 0.968,1.03 5520 17820
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.9616 1.0 0.907,1.11 419 4137 0.4335 1.05 0.927,1.19 259 2450
427.41 Ventricular fibrillation and flutter circulatory system Both 0.6026 0.96 0.822,1.12 167 1670 0.7063 0.967 0.81,1.15 128 1242
427.42 Cardiac arrest circulatory system Both 0.2965 1.06 0.949,1.19 321 3186 0.4335 1.05 0.927,1.19 259 2450
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.7709 0.995 0.966,1.03 5521 21271 0.6855 0.993 0.959,1.03 4189 17814
427.6 Premature beats circulatory system Both 0.6427 1.01 0.963,1.06 1820 13218 0.7194 1.02 0.918,1.13 381 3608
427.61 Supraventricular premature beats circulatory system Both 0.1483 1.07 0.977,1.17 522 4879 0.7194 1.02 0.918,1.13 381 3608
427.7 Tachycardia NOS circulatory system Both 0.8147 1.0 0.97,1.04 3980 21286 0.6053 1.01 0.973,1.05 3187 17832
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.6776 0.984 0.911,1.06 738 6224 0.2805 0.95 0.867,1.04 519 4559
427.9 Palpitations circulatory system Both 0.3707 1.02 0.98,1.05 3420 20157 0.1371 1.03 0.99,1.07 2716 16745
428 Congestive heart failure; nonhypertensive circulatory system Both 0.8375 1.0 0.967,1.04 3326 19946 0.5572 1.02 0.953,1.09 894 7866
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.9977 1.0 0.961,1.04 2965 19130 0.873 1.0 0.959,1.05 2236 15031
428.2 Heart failure NOS circulatory system Both 0.5272 1.01 0.973,1.05 2781 17962 0.3388 1.02 0.977,1.07 2097 14010
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.1306 1.05 0.987,1.11 1288 11396 0.0955 1.06 0.99,1.13 994 8567
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.6776 1.01 0.954,1.07 1208 10616 0.5572 1.02 0.953,1.09 894 7866
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.4074 1.01 0.986,1.03 9394 27581 0.6012 0.974 0.884,1.07 454 4272
429.1 Heart transplant/surgery circulatory system Both 0.2089 0.955 0.888,1.03 823 8070 0.7278 0.986 0.909,1.07 647 6111
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.8531 1.0 0.971,1.04 4445 23965 0.6823 1.01 0.971,1.05 3366 19398
429.3 Symptoms involving cardiovascular system circulatory system Both 0.2904 1.01 0.988,1.04 7147 27443 0.1986 1.02 0.99,1.05 5562 22731
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.7925 0.989 0.909,1.08 591 5816 0.6012 0.974 0.884,1.07 454 4272
430 Intracranial hemorrhage circulatory system Both 0.07586 1.08 0.992,1.17 633 6305 0.4305 1.07 0.91,1.25 159 1508
430.1 Subarachnoid hemorrhage circulatory system Both 0.1995 1.09 0.955,1.24 230 2300 0.2109 1.1 0.949,1.27 188 1767
430.2 Intracerebral hemorrhage circulatory system Both 0.09772 1.1 0.982,1.24 314 3132 0.134 1.11 0.969,1.26 242 2445
430.3 Subdural hemorrhage circulatory system Both 0.7943 0.981 0.851,1.13 202 2017 0.4305 1.07 0.91,1.25 159 1508
433 Cerebrovascular disease circulatory system Both 0.3846 1.01 0.982,1.05 4361 26660 0.8147 1.01 0.914,1.12 400 4007
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.955 0.999 0.947,1.05 1533 12978 0.1524 1.13 0.955,1.35 147 1358
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.4797 1.06 0.908,1.23 188 1858 0.1524 1.13 0.955,1.35 147 1358
433.12 Cerebral atherosclerosis circulatory system Both 0.1205 0.811 0.623,1.06 61 599 ,
433.2 Occlusion of cerebral arteries circulatory system Both 0.9333 0.998 0.952,1.05 1926 17593 0.6486 1.01 0.959,1.07 1387 12926
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.8337 0.995 0.948,1.04 1862 17011 0.6486 1.01 0.959,1.07 1387 12926
433.3 Cerebral ischemia circulatory system Both 0.5623 1.01 0.969,1.06 2122 18040 0.9908 1.0 0.945,1.06 1322 12123
433.31 Transient cerebral ischemia circulatory system Both 0.8892 0.997 0.95,1.05 1812 16062 0.9908 1.0 0.945,1.06 1322 12123
433.5 Cerebral aneurysm circulatory system Both 0.01585 1.13 1.02,1.25 408 4070 0.0123 1.15 1.03,1.28 349 3219
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.929 0.995 0.897,1.1 383 3803 0.9817 0.999 0.885,1.13 283 2792
433.8 Late effects of cerebrovascular disease circulatory system Both 0.5916 0.976 0.893,1.07 534 5286 0.8147 1.01 0.914,1.12 400 4007
440 Atherosclerosis circulatory system Both 0.2838 0.975 0.93,1.02 1946 16499 0.7096 0.983 0.898,1.08 527 4865
440.1 Atherosclerosis of renal artery circulatory system Both 0.9817 0.998 0.863,1.15 187 1855 0.3483 0.923 0.78,1.09 144 1365
440.2 Atherosclerosis of the extremities circulatory system Both 0.3936 0.974 0.917,1.03 1166 11265 0.4355 0.967 0.889,1.05 617 5845
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.4955 1.05 0.909,1.22 183 1815 0.5623 1.05 0.886,1.25 137 1368
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.08128 0.937 0.871,1.01 812 7979 0.4355 0.967 0.889,1.05 617 5845
440.9 Atherosclerosis of aorta circulatory system Both 0.25 0.955 0.883,1.03 702 6800 0.7096 0.983 0.898,1.08 527 4865
441 Vascular insufficiency of intestine circulatory system Both 0.4426 1.04 0.941,1.15 407 4039 0.9078 1.01 0.826,1.24 105 915
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.3491 1.07 0.93,1.23 206 2025 0.1816 1.11 0.953,1.29 172 1590
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.4864 0.935 0.773,1.13 122 1207 0.9078 1.01 0.826,1.24 105 915
442 Other aneurysm circulatory system Both 0.4864 0.985 0.943,1.03 2309 18098 0.881 0.99 0.873,1.12 258 2513
442.1 Aortic aneurysm circulatory system Both 0.08913 0.957 0.91,1.01 1703 13812 0.7499 0.988 0.915,1.07 728 6491
442.11 Abdominal aortic aneurysm circulatory system Both 0.04266 0.934 0.874,0.998 992 9021 0.7499 0.988 0.915,1.07 728 6491
442.2 Aneurysm of iliac artery circulatory system Both 0.5689 1.04 0.898,1.22 177 1769 0.3945 1.08 0.905,1.29 133 1242
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.4519 0.934 0.783,1.12 137 1357 0.7482 1.03 0.852,1.25 116 1003
442.4 Arterial dissection circulatory system Both 0.3467 0.923 0.78,1.09 156 1555 0.6353 0.955 0.791,1.15 125 1192
442.8 Aneurysm of other specified artery circulatory system Both 0.5383 0.965 0.862,1.08 330 3300 0.881 0.99 0.873,1.12 258 2513
443 Peripheral vascular disease circulatory system Both 0.7852 0.994 0.953,1.04 2355 20353 0.9795 1.0 0.945,1.06 1326 11425
443.1 Raynaud's syndrome circulatory system Both 0.7211 1.02 0.935,1.1 608 6051 0.7943 1.01 0.925,1.11 500 5023
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.1086 1.15 0.97,1.35 141 1375 0.2748 1.12 0.916,1.36 103 1029
443.8 Other specified peripheral vascular diseases circulatory system Both 0.8054 1.01 0.959,1.05 1899 17476 0.5346 1.02 0.964,1.07 1480 13483
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.4842 0.982 0.935,1.03 1747 15154 0.9795 1.0 0.945,1.06 1326 11425
444 Arterial embolism and thrombosis circulatory system Both 0.4864 0.972 0.898,1.05 675 6732 0.9397 0.992 0.803,1.22 101 955
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.492 0.955 0.839,1.09 240 2392 0.863 1.01 0.878,1.17 202 1782
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.9484 0.994 0.828,1.19 129 1282 0.9397 0.992 0.803,1.22 101 955
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.2188 1.07 0.962,1.18 367 3641 0.5129 1.05 0.906,1.22 178 1813
446.4 Wegener's granulomatosis circulatory system Both 0.9247 0.99 0.803,1.22 86 857 0.7638 0.963 0.754,1.23 65 693
446.5 Giant cell arteritis circulatory system Both 0.3614 1.13 0.868,1.48 59 547 ,
446.9 Arteritis NOS circulatory system Both 0.2018 1.09 0.956,1.24 230 2285 0.5129 1.05 0.906,1.22 178 1813
447 Other disorders of arteries and arterioles circulatory system Both 0.06607 0.958 0.916,1.0 2116 18819 0.673 0.979 0.889,1.08 461 4705
447.1 Stricture of artery circulatory system Both 0.4036 0.958 0.866,1.06 435 4322 0.8414 0.989 0.883,1.11 344 3265
447.7 Aortic ectasia circulatory system Both 0.3873 0.965 0.889,1.05 637 6315 0.673 0.979 0.889,1.08 461 4705
448 Disease of capillaries circulatory system Both 0.1247 1.06 0.985,1.13 853 8472 0.1442 0.927 0.837,1.03 397 6572
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.06457 1.05 0.997,1.1 1701 17006 0.3532 0.971 0.912,1.03 1057 13663
451 Phlebitis and thrombophlebitis circulatory system Both 0.7015 0.983 0.903,1.07 582 5764 0.7362 0.971 0.817,1.15 150 1528
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.7998 0.981 0.842,1.14 190 1888 0.7362 0.971 0.817,1.15 150 1528
452 Other venous embolism and thrombosis circulatory system Both 0.1007 0.971 0.938,1.01 3773 25068 0.4083 0.92 0.754,1.12 109 1026
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.5834 1.04 0.909,1.18 228 2277 0.912 1.01 0.865,1.18 174 1826
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.2438 0.976 0.937,1.02 2623 22444 0.2576 0.974 0.93,1.02 2062 18336
452.8 Postphlebitic syndrome circulatory system Both 0.3451 0.912 0.753,1.1 119 1181 0.4083 0.92 0.754,1.12 109 1026
453 Chronic venous hypertension circulatory system Both 0.9311 1.01 0.864,1.17 173 1715 0.7727 1.03 0.863,1.22 136 1379
454 Varicose veins circulatory system Both 0.08913 0.962 0.92,1.01 2206 20243 0.03467 0.927 0.864,0.995 879 9446
454.1 Varicose veins of lower extremity circulatory system Both 0.09333 0.96 0.915,1.01 1908 17574 0.03467 0.927 0.864,0.995 879 9446
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.01738 0.929 0.874,0.987 1182 11754 0.03467 0.927 0.864,0.995 879 9446
455 Hemorrhoids circulatory system Both 0.9683 1.0 0.969,1.03 4379 24588 0.8395 1.0 0.968,1.04 3337 20307
456 Chronic venous insufficiency [CVI] circulatory system Both 0.04074 0.956 0.915,0.998 2303 20367 0.02344 0.945 0.899,0.992 1793 16537
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.5395 1.01 0.968,1.06 1946 14131 0.2825 1.03 0.975,1.09 1348 10597
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.2065 0.924 0.817,1.04 287 2845 0.4009 0.94 0.814,1.09 211 2118
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.3837 1.02 0.973,1.07 1841 13661 0.2825 1.03 0.975,1.09 1348 10597
458 Hypotension circulatory system Both 0.9099 0.998 0.966,1.03 4073 28546 0.6998 0.992 0.954,1.03 2764 22117
458.1 Orthostatic hypotension circulatory system Both 0.3556 1.03 0.967,1.1 1031 10176 0.7211 0.987 0.916,1.06 763 7873
458.2 Iatrogenic hypotension circulatory system Both 0.8974 0.996 0.931,1.07 911 9084 0.7516 1.01 0.938,1.09 693 6898
458.9 Hypotension NOS circulatory system Both 0.869 0.997 0.963,1.03 3641 27465 0.6998 0.992 0.954,1.03 2764 22117
459 Other disorders of circulatory system circulatory system Both 0.1472 1.03 0.991,1.06 3553 27674 0.2692 1.03 0.981,1.07 2093 18677
459.1 Hemorrhage NOS circulatory system Both 0.1271 1.06 0.982,1.15 619 6159 0.5408 1.03 0.938,1.13 455 4751
459.7 Blood vessel replaced circulatory system Both 0.9016 1.01 0.874,1.17 203 2030 0.9795 0.998 0.851,1.17 170 1546
459.9 Circulatory disease NEC circulatory system Both 0.2244 1.02 0.985,1.07 2757 23656 0.2692 1.03 0.981,1.07 2093 18677
464 Acute sinusitis respiratory Both 0.1002 0.971 0.938,1.01 3675 26562 0.1135 0.969 0.933,1.01 2981 21865
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.3013 1.01 0.988,1.04 7223 30143 0.03388 1.14 1.01,1.29 266 2844
465.2 Acute pharyngitis respiratory Both 0.955 1.0 0.968,1.04 3967 26715 0.6887 1.01 0.971,1.05 3354 22211
465.4 Acute laryngitis and tracheitis respiratory Both 0.1222 1.09 0.977,1.21 345 3441 0.03388 1.14 1.01,1.29 266 2844
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.7228 1.01 0.956,1.07 1431 14130 0.8035 1.01 0.949,1.07 1184 12061
471 Nasal polyps respiratory Both 0.618 0.976 0.887,1.07 475 4727 0.811 0.987 0.889,1.1 390 3922
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.08318 0.951 0.899,1.01 1344 13251 0.1714 0.957 0.899,1.02 1084 10935
473 Diseases of the larynx and vocal cords respiratory Both 0.6808 1.01 0.967,1.05 2393 20985 0.3319 0.973 0.921,1.03 1394 14492
473.1 Chronic laryngitis respiratory Both 0.7586 1.04 0.791,1.38 57 562 ,
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.4385 0.965 0.881,1.06 517 5167 0.6918 0.98 0.885,1.08 408 4118
473.4 Voice disturbance respiratory Both 0.8414 0.995 0.949,1.04 1880 18033 0.3319 0.973 0.921,1.03 1394 14492
474 Acute and chronic tonsillitis respiratory Both 0.7482 0.987 0.911,1.07 685 6193 0.6792 0.98 0.893,1.08 496 4666
474.1 Acute tonsillitis respiratory Both 0.2877 1.07 0.944,1.22 267 2507 0.3908 1.06 0.93,1.2 258 2337
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.7211 0.984 0.9,1.08 555 5166 0.6792 0.98 0.893,1.08 496 4666
475 Chronic sinusitis respiratory Both 0.5297 0.988 0.953,1.02 3434 23149 0.4699 0.966 0.878,1.06 484 5170
475.9 Postnasal drip respiratory Both 0.4375 0.968 0.893,1.05 651 6441 0.4699 0.966 0.878,1.06 484 5170
476 Allergic rhinitis respiratory Both 0.6683 1.01 0.982,1.03 10205 23354 0.7129 0.995 0.969,1.02 8157 19306
477 Epistaxis or throat hemorrhage respiratory Both 0.413 0.971 0.906,1.04 895 8841 0.2472 0.954 0.88,1.03 672 7131
478 Throat pain respiratory Both 0.4603 0.957 0.852,1.08 325 3233 0.5188 0.957 0.837,1.09 241 2695
479 Other upper respiratory disease respiratory Both 0.6966 0.994 0.962,1.03 4428 23338 0.5358 0.989 0.953,1.03 3438 19291
480 Pneumonia respiratory Both 0.6792 1.01 0.976,1.04 4823 30881 0.3508 1.1 0.896,1.36 92 898
480.1 Bacterial pneumonia respiratory Both 0.9099 1.0 0.936,1.08 860 8567 0.4375 1.11 0.854,1.44 64 653
480.11 Pneumococcal pneumonia respiratory Both 0.6823 0.978 0.877,1.09 372 3720 0.8892 0.991 0.873,1.13 269 2955
480.12 Pseudomonal pneumonia respiratory Both 0.4227 1.08 0.898,1.29 121 1192 0.2911 1.12 0.905,1.39 87 947
480.13 MRSA pneumonia respiratory Both 0.7674 0.965 0.761,1.22 82 818 0.4375 1.11 0.854,1.44 64 653
480.2 Viral pneumonia respiratory Both 0.7907 0.978 0.826,1.16 147 1461 0.5888 0.944 0.765,1.16 96 1154
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.5445 1.06 0.881,1.27 117 1170 0.3236 1.11 0.9,1.37 83 913
480.5 Bronchopneumonia and lung abscess respiratory Both 0.5105 1.06 0.886,1.28 119 1175 0.3508 1.1 0.896,1.36 92 898
481 Influenza respiratory Both 0.1603 0.954 0.892,1.02 990 9863 0.2339 0.955 0.886,1.03 774 8133
483 Acute bronchitis and bronchiolitis respiratory Both 0.7798 1.01 0.966,1.05 2615 24227 0.7211 1.01 0.964,1.05 2077 19628
495 Asthma respiratory Both 0.2333 1.02 0.99,1.04 6951 27725 0.9616 1.0 0.941,1.07 1068 10524
495.1 Chronic obstructive asthma respiratory Both 0.4121 0.955 0.855,1.07 341 3403 0.9441 1.0 0.89,1.13 274 2632
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.6138 0.935 0.719,1.22 60 592 ,
495.2 Asthma with exacerbation respiratory Both 0.7112 1.01 0.954,1.07 1251 12442 0.9616 1.0 0.941,1.07 1068 10524
496 Chronic airway obstruction respiratory Both 0.5297 0.99 0.958,1.02 4444 23893 0.4898 1.04 0.929,1.17 313 3225
496.1 Emphysema respiratory Both 0.2735 0.973 0.927,1.02 1831 16712 0.1169 0.955 0.903,1.01 1345 12607
496.2 Chronic bronchitis respiratory Both 0.6871 0.993 0.957,1.03 3357 22668 0.4656 1.02 0.973,1.06 2360 16909
496.21 Obstructive chronic bronchitis respiratory Both 0.6745 0.992 0.955,1.03 3040 21701 0.4656 1.02 0.973,1.06 2360 16909
496.3 Bronchiectasis respiratory Both 0.8414 1.01 0.916,1.11 435 4329 0.4898 1.04 0.929,1.17 313 3225
497 Bronchitis respiratory Both 0.5495 0.984 0.933,1.04 1481 14700 0.5047 0.98 0.922,1.04 1154 11728
498 Acute bronchospasm respiratory Both 0.2113 1.07 0.963,1.18 376 3745 0.2547 1.07 0.954,1.19 317 3123
499 Cystic fibrosis respiratory Both 0.03236 0.804 0.658,0.982 116 1160 0.2985 0.892 0.718,1.11 93 977
500 Lung disease due to external agents respiratory Both 0.8166 1.01 0.918,1.12 428 4273 0.3707 0.885 0.677,1.16 57 617
500.1 Extrinsic allergic alveolitis respiratory Both 0.2089 0.862 0.683,1.09 81 810 0.3707 0.885 0.677,1.16 57 617
500.2 Pneumoconiosis respiratory Both 0.881 0.982 0.772,1.25 65 640 ,
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.8185 1.01 0.924,1.11 514 5078 0.2009 1.07 0.964,1.19 360 3812
502 Postinflammatory pulmonary fibrosis respiratory Both 0.811 1.01 0.93,1.1 623 6192 0.7727 1.01 0.92,1.12 456 4567
503 Pulmonary congestion and hypostasis respiratory Both 0.8414 0.992 0.918,1.07 690 6875 0.2455 1.05 0.965,1.15 548 5197
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.5297 0.969 0.879,1.07 447 4454 0.507 0.949 0.814,1.11 180 1829
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.2897 0.931 0.815,1.06 247 2456 0.507 0.949 0.814,1.11 180 1829
505 Other pulmonary inflamation or edema respiratory Both 0.5383 0.983 0.929,1.04 1352 13261 0.9683 1.0 0.94,1.07 1051 10125
506 Empyema and pneumothorax respiratory Both 0.007762 0.946 0.908,0.985 2588 22332 0.09772 0.962 0.918,1.01 2049 17721
507 Pleurisy; pleural effusion respiratory Both 0.4498 1.02 0.975,1.06 2415 21828 0.1156 1.04 0.991,1.09 1836 17144
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 1.0 1.0 0.955,1.05 2005 19256 0.5082 1.02 0.966,1.07 1527 15072
509 Respiratory failure, insufficiency, arrest respiratory Both 0.6776 0.992 0.955,1.03 3044 23898 0.3062 1.04 0.963,1.13 666 6556
509.1 Respiratory failure respiratory Both 0.7499 0.991 0.94,1.05 1466 14560 0.4436 1.02 0.964,1.09 1133 11276
509.2 Respiratory insufficiency respiratory Both 0.3404 1.03 0.966,1.1 928 9238 0.1119 1.06 0.986,1.15 723 7097
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.7852 1.01 0.955,1.06 1500 14783 0.06026 1.06 0.998,1.12 1195 11433
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.9354 0.997 0.93,1.07 848 8472 0.3062 1.04 0.963,1.13 666 6556
510 Other diseases of lung respiratory Both 0.9661 1.0 0.97,1.03 4671 30168 0.6531 0.951 0.766,1.18 82 1015
510.2 Lung transplant respiratory Both 0.7691 0.974 0.816,1.16 128 1274 0.6531 0.951 0.766,1.18 82 1015
512 Other symptoms of respiratory system respiratory Both 0.1816 0.986 0.966,1.01 14878 23476 0.547 0.991 0.964,1.02 6886 19362
512.1 Wheezing respiratory Both 0.6138 0.984 0.924,1.05 1071 10626 0.9772 1.0 0.932,1.07 824 8539
512.2 Painful respiration respiratory Both 0.1435 0.964 0.917,1.01 1765 17029 0.3184 0.972 0.919,1.03 1376 13799
512.3 Abnormal chest sounds respiratory Both 0.8356 0.986 0.86,1.13 229 2261 0.6699 1.04 0.88,1.22 156 1651
512.7 Shortness of breath respiratory Both 0.3119 0.987 0.961,1.01 7928 23452 0.863 1.0 0.974,1.03 6233 19347
512.8 Cough respiratory Both 0.2113 0.983 0.957,1.01 7280 23469 0.5346 0.991 0.961,1.02 5685 19367
512.9 Other dyspnea respiratory Both 0.104 0.979 0.955,1.0 8658 23467 0.547 0.991 0.964,1.02 6886 19362
513 Respiratory abnormalities respiratory Both 0.4808 0.992 0.969,1.01 10231 28110 0.0955 1.15 0.976,1.35 153 1508
513.3 Hypoventilation respiratory Both 0.7621 1.01 0.932,1.1 618 6146 0.5598 1.06 0.879,1.27 126 1250
513.31 Apnea respiratory Both 0.6152 0.971 0.865,1.09 314 3136 1.0 1.0 0.881,1.14 258 2485
513.32 Orthopnea respiratory Both 0.4375 1.06 0.91,1.24 167 1662 0.5598 1.06 0.879,1.27 126 1250
513.4 Hyperventilation respiratory Both 0.9594 0.997 0.905,1.1 440 4383 0.3412 1.06 0.944,1.18 326 3338
513.8 Disorders of diaphragm respiratory Both 0.1702 1.11 0.958,1.27 206 2053 0.0955 1.15 0.976,1.35 153 1508
514 Abnormal findings examination of lungs respiratory Both 0.4571 1.01 0.981,1.04 4486 29229 0.6668 0.989 0.941,1.04 1695 17930
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.7762 0.978 0.842,1.14 193 1914 0.859 0.984 0.826,1.17 133 1472
514.2 Solitary pulmonary nodule respiratory Both 0.7656 1.01 0.966,1.05 2489 22668 0.6668 0.989 0.941,1.04 1695 17930
516 Abnormal sputum respiratory Both 0.3069 1.05 0.96,1.14 565 5640 0.1524 1.08 0.971,1.21 350 3682
516.1 Hemoptysis respiratory Both 0.25 1.06 0.962,1.16 473 4720 0.1524 1.08 0.971,1.21 350 3682
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.2344 0.982 0.953,1.01 5153 32053 0.354 0.982 0.946,1.02 3072 23541
519.1 Tracheostomy complications respiratory Both 0.5702 0.956 0.818,1.12 176 1760 0.7998 0.976 0.812,1.17 121 1382
519.2 Respiratory complications respiratory Both 0.526 1.04 0.93,1.15 370 3696 0.175 1.08 0.965,1.22 307 2944
519.8 Other diseases of respiratory system, NEC respiratory Both 0.7145 1.01 0.945,1.09 887 8857 0.4775 1.03 0.95,1.12 652 7077
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.0912 0.972 0.94,1.0 4043 29199 0.354 0.982 0.946,1.02 3072 23541
520 Disorders of tooth development digestive Both 0.3319 1.06 0.941,1.2 291 2900 0.4027 1.07 0.913,1.25 157 1496
520.1 Hereditary disturbances in tooth structure digestive Both 0.4009 1.08 0.903,1.29 131 1301 0.9162 1.01 0.812,1.26 88 1085
520.2 Disturbances in tooth eruption digestive Both 0.6668 1.03 0.887,1.21 172 1693 0.4027 1.07 0.913,1.25 157 1496
521 Diseases of hard tissues of teeth digestive Both 0.7499 0.988 0.914,1.07 719 7167 0.695 0.981 0.893,1.08 474 5536
521.1 Dental caries digestive Both 0.9594 1.0 0.926,1.08 673 6709 0.695 0.981 0.893,1.08 474 5536
522 Diseases of pulp and periapical tissues digestive Both 0.6902 0.98 0.885,1.08 408 4067 0.3855 0.947 0.837,1.07 287 2820
522.5 Periapical abscess digestive Both 0.3648 0.949 0.848,1.06 341 3404 0.3855 0.947 0.837,1.07 287 2820
523 Gingival and periodontal diseases digestive Both 0.1954 0.944 0.865,1.03 569 5690 0.8166 0.971 0.754,1.25 67 824
523.1 Gingivitis digestive Both 0.04571 0.815 0.666,0.996 117 1163 0.03467 0.767 0.601,0.981 79 972
523.3 Periodontitis (acute or chronic) digestive Both 0.2307 0.929 0.823,1.05 294 2940 0.8166 0.971 0.754,1.25 67 824
523.31 Acute periodontitis digestive Both 0.2061 0.92 0.808,1.05 251 2510 0.07943 0.875 0.753,1.02 190 2062
523.32 Chronic periodontitis digestive Both 0.984 1.0 0.818,1.23 103 1030 0.8166 0.971 0.754,1.25 67 824
524 Dentofacial anomalies, including malocclusion digestive Both 0.9528 1.0 0.893,1.13 308 3080 0.0955 1.14 0.978,1.33 169 1692
524.3 Anomalies of tooth position/malocclusion digestive Both 0.08511 1.14 0.982,1.31 186 1856 0.0955 1.14 0.978,1.33 169 1692
525 Other diseases of the teeth and supporting structures digestive Both 0.955 1.0 0.934,1.07 853 8530 0.1858 0.911 0.794,1.05 230 2638
525.1 Loss of teeth or edentulism digestive Both 0.3381 0.944 0.84,1.06 318 3178 0.1858 0.911 0.794,1.05 230 2638
526 Diseases of the jaws digestive Both 0.929 1.0 0.958,1.05 2140 21162 0.7516 1.02 0.905,1.15 284 3243
526.1 Cysts of the jaws digestive Both 0.857 1.01 0.88,1.17 213 2123 0.2812 1.08 0.935,1.26 186 1782
526.3 Anomalies of jaw size/symmetry digestive Both 0.2218 1.09 0.949,1.25 206 2052 0.4498 1.06 0.916,1.22 189 1873
526.4 Temporomandibular joint disorders digestive Both 0.5794 0.983 0.926,1.04 1178 11779 0.9954 1.0 0.915,1.09 517 5214
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.8892 1.0 0.94,1.07 941 9410 0.9397 1.0 0.933,1.08 802 8033
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.7925 1.01 0.93,1.1 600 5993 0.9954 1.0 0.915,1.09 517 5214
526.5 Inflammatory conditions of jaw digestive Both 0.07943 0.888 0.778,1.01 242 2405 0.00955 0.799 0.674,0.947 152 1967
526.9 Jaw disease NOS digestive Both 0.2858 1.06 0.955,1.17 399 3982 0.7516 1.02 0.905,1.15 284 3243
527 Diseases of the salivary glands digestive Both 0.2421 0.967 0.914,1.02 1362 13604 0.5821 0.953 0.802,1.13 133 1545
527.2 Sialoadenitis digestive Both 0.7691 1.02 0.907,1.14 320 3200 0.7063 0.976 0.86,1.11 262 2570
527.7 Disturbance of salivary secretion digestive Both 0.7413 0.987 0.913,1.07 715 7141 0.3428 0.95 0.855,1.06 390 5570
527.8 Other specified diseases of the salivary glands digestive Both 0.618 0.964 0.835,1.11 196 1960 0.5821 0.953 0.802,1.13 133 1545
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.5675 0.987 0.944,1.03 2077 20750 0.005248 0.752 0.615,0.919 116 1070
528.1 Stomatitis and mucositis digestive Both 0.7047 1.02 0.932,1.11 536 5360 0.881 1.01 0.853,1.2 129 1433
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.3076 0.922 0.789,1.08 165 1650 0.07762 0.836 0.685,1.02 107 1354
528.12 Oral aphthae digestive Both 0.6026 1.04 0.894,1.21 170 1700 0.881 1.01 0.853,1.2 129 1433
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.389 0.935 0.801,1.09 185 1837 0.7211 0.969 0.813,1.15 138 1553
528.4 Cysts of oral soft tissues digestive Both 0.6471 0.955 0.783,1.16 110 1096 0.6442 0.935 0.702,1.25 56 562
528.41 Cyst of the salivary gland digestive Both 0.7762 0.964 0.75,1.24 68 679 0.6442 0.935 0.702,1.25 56 562
528.5 Diseases of lips digestive Both 0.04169 1.12 1.0,1.25 334 3340 0.1742 1.1 0.959,1.26 209 2739
528.6 Leukoplakia of oral mucosa digestive Both 0.9376 1.01 0.832,1.22 113 1120 0.7211 0.951 0.719,1.26 54 869
528.7 Sialolithiasis digestive Both 0.002692 0.75 0.622,0.905 132 1320 0.005248 0.752 0.615,0.919 116 1070
529 Diseases and other conditions of the tongue digestive Both 0.3581 1.04 0.955,1.14 541 5402 0.2307 1.14 0.922,1.4 92 1056
529.1 Glossitis digestive Both 0.1175 1.18 0.959,1.45 99 982 0.2506 1.16 0.9,1.5 67 771
529.6 Glossodynia digestive Both 0.2344 1.11 0.934,1.32 136 1355 0.2307 1.14 0.922,1.4 92 1056
530 Diseases of esophagus digestive Both 0.8831 1.0 0.98,1.02 13874 23034 0.3954 0.972 0.909,1.04 947 9782
530.1 Esophagitis, GERD and related diseases digestive Both 0.8433 1.0 0.981,1.02 13419 23031 0.3126 1.1 0.915,1.32 122 1245
530.11 GERD digestive Both 0.7278 1.0 0.982,1.03 13059 23031 0.3319 1.01 0.988,1.04 10413 19159
530.12 Ulcer of esophagus digestive Both 0.5572 0.965 0.857,1.09 298 2973 0.881 0.99 0.865,1.13 230 2328
530.13 Barrett's esophagus digestive Both 0.09772 0.932 0.857,1.01 609 6080 0.02239 0.894 0.812,0.984 474 4674
530.14 Reflux esophagitis digestive Both 0.4178 0.978 0.927,1.03 1483 14213 0.8299 0.993 0.935,1.06 1133 11236
530.15 Eosinophilic esophagitis digestive Both 0.3034 1.09 0.924,1.29 145 1441 0.3126 1.1 0.915,1.32 122 1245
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.5741 0.973 0.885,1.07 475 4742 0.9354 1.0 0.901,1.12 369 3737
530.3 Stricture and stenosis of esophagus digestive Both 0.1552 1.06 0.98,1.14 752 7474 0.1186 1.07 0.983,1.17 570 5781
530.5 Disorders of esophageal motility digestive Both 0.5848 0.973 0.881,1.07 434 4326 0.6368 0.974 0.873,1.09 350 3356
530.6 Diverticulum of esophagus, acquired digestive Both 0.5047 0.939 0.782,1.13 121 1181 0.6295 0.95 0.772,1.17 95 846
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.3013 0.875 0.68,1.13 70 700 0.07586 0.766 0.571,1.03 54 544
530.9 Heartburn digestive Both 0.4634 0.978 0.922,1.04 1198 11946 0.3954 0.972 0.909,1.04 947 9782
531 Peptic ulcer (excl. esophageal) digestive Both 0.3006 1.03 0.976,1.08 1608 16066 0.002951 1.36 1.11,1.66 97 912
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.09333 1.1 0.984,1.24 311 3103 0.0631 1.13 0.993,1.29 234 2273
531.2 Gastric ulcer digestive Both 0.08913 1.06 0.991,1.14 884 8834 0.03981 1.08 1.0,1.17 693 6929
531.3 Duodenal ulcer digestive Both 0.4819 1.04 0.934,1.16 362 3613 0.2877 1.07 0.946,1.21 280 2741
531.4 Peptic ulcer, site unspecified digestive Both 0.9057 0.995 0.918,1.08 632 6313 0.8222 0.99 0.904,1.08 499 4858
531.5 Gastrojejunal ulcer digestive Both 0.02188 1.24 1.03,1.49 115 1143 0.002951 1.36 1.11,1.66 97 912
532 Dysphagia digestive Both 0.9594 1.0 0.969,1.03 4457 22190 0.2239 1.02 0.986,1.06 3277 18348
535 Gastritis and duodenitis digestive Both 0.5957 0.988 0.945,1.03 2129 21208 0.9638 1.0 0.93,1.08 780 7932
535.1 Acute gastritis digestive Both 0.5768 1.02 0.95,1.1 814 8139 0.399 1.04 0.955,1.12 646 6430
535.2 Atrophic gastritis digestive Both 0.514 1.04 0.919,1.18 250 2500 0.3631 1.07 0.929,1.22 213 2013
535.6 Duodenitis digestive Both 0.7907 1.02 0.896,1.16 265 2650 0.2858 1.08 0.937,1.25 209 2084
535.8 Other specified gastritis digestive Both 0.4842 0.968 0.883,1.06 497 4964 0.7762 0.985 0.888,1.09 390 3922
535.9 Gastritis and duodenitis, NOS digestive Both 0.3622 0.97 0.908,1.04 985 9835 0.9638 1.0 0.93,1.08 780 7932
536 Disorders of function of stomach digestive Both 0.4009 0.982 0.94,1.03 2251 22311 0.6412 0.987 0.933,1.04 1340 13634
536.3 Gastroparesis digestive Both 0.05623 0.913 0.831,1.0 489 4876 0.2529 0.941 0.848,1.04 392 4057
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.9268 0.995 0.887,1.12 334 3331 0.4613 1.05 0.922,1.2 253 2641
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.455 0.981 0.933,1.03 1699 16834 0.6412 0.987 0.933,1.04 1340 13634
537 Other disorders of stomach and duodenum digestive Both 0.309 0.978 0.937,1.02 2357 23199 0.06607 0.821 0.664,1.01 97 936
537.1 Lesions of stomach and duodenum digestive Both 0.1291 0.869 0.725,1.04 128 1271 0.06607 0.821 0.664,1.01 97 936
539 Bariatric surgery digestive Both 0.3917 1.03 0.966,1.09 1118 11180 0.1683 1.05 0.981,1.12 996 9391
540 Appendiceal conditions digestive Both 0.8531 0.99 0.893,1.1 399 3990 0.7816 1.02 0.894,1.16 250 2468
540.1 Appendicitis digestive Both 0.8851 1.01 0.903,1.13 349 3490 0.7816 1.02 0.894,1.16 250 2468
540.11 Acute appendicitis digestive Both 0.8054 1.02 0.9,1.15 293 2930 0.7816 1.02 0.894,1.16 250 2468
550 Abdominal hernia digestive Both 0.4406 0.989 0.96,1.02 5517 31191 0.4831 0.976 0.911,1.04 908 8582
550.1 Inguinal hernia digestive Both 0.2825 0.97 0.918,1.03 1427 13556 0.4519 0.976 0.915,1.04 1068 10437
550.2 Diaphragmatic hernia digestive Both 0.8511 0.996 0.954,1.04 2290 21266 0.9183 0.997 0.95,1.05 1768 16477
550.3 Femoral hernia digestive Both 0.7112 0.962 0.783,1.18 109 1082 0.6397 0.946 0.748,1.19 84 864
550.4 Umbilical hernia digestive Both 0.7709 0.991 0.93,1.06 1053 10514 0.6516 1.02 0.948,1.09 872 8315
550.5 Ventral hernia digestive Both 0.3105 0.975 0.93,1.02 1826 18190 0.857 1.0 0.953,1.06 1484 14153
550.6 Incisional hernia digestive Both 0.1045 0.95 0.892,1.01 1101 10999 0.4831 0.976 0.911,1.04 908 8582
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.492 1.02 0.963,1.08 1275 12527 0.7656 1.02 0.913,1.13 370 3733
555.1 Regional enteritis digestive Both 0.6516 0.983 0.913,1.06 775 7701 0.5082 0.974 0.9,1.05 674 6569
555.2 Ulcerative colitis digestive Both 0.879 1.01 0.934,1.08 768 7591 0.7656 1.02 0.913,1.13 370 3733
555.21 Ulcerative colitis (chronic) digestive Both 0.7362 1.02 0.922,1.12 438 4361 0.7656 1.02 0.913,1.13 370 3733
556 Ulceration of the lower GI tract digestive Both 0.3882 0.959 0.873,1.05 473 4719 0.8356 0.979 0.802,1.2 100 1053
556.1 Ulceration of intestine digestive Both 0.6592 0.978 0.884,1.08 412 4099 0.8356 0.979 0.802,1.2 100 1053
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.9772 0.998 0.847,1.17 152 1496 0.8356 0.979 0.802,1.2 100 1053
557 Intestinal malabsorption (non-celiac) digestive Both 0.4529 0.978 0.924,1.04 1306 12565 0.4395 0.951 0.836,1.08 258 2552
557.1 Celiac disease digestive Both 0.4467 0.955 0.847,1.08 305 3050 0.4395 0.951 0.836,1.08 258 2552
558 Noninfectious gastroenteritis digestive Both 0.7311 1.01 0.967,1.05 2706 20417 0.7031 1.01 0.965,1.05 2170 16925
559 Ileostomy status digestive Both 0.06761 0.933 0.865,1.01 773 7702 0.2455 0.953 0.878,1.03 652 6138
560 Intestinal obstruction without mention of hernia digestive Both 0.9506 0.999 0.959,1.04 2580 20303 0.5117 1.02 0.962,1.08 1209 11624
560.1 Paralytic ileus digestive Both 0.3631 0.975 0.923,1.03 1429 13524 0.4009 0.974 0.917,1.04 1165 10720
560.2 Impaction of intestine digestive Both 0.6699 1.03 0.904,1.17 257 2499 0.4406 1.06 0.917,1.22 207 2068
560.3 Peritoneal or intestinal adhesions digestive Both 0.7852 1.02 0.899,1.15 261 2599 0.3715 1.07 0.927,1.22 202 2075
560.4 Other intestinal obstruction digestive Both 0.537 1.02 0.964,1.07 1489 14381 0.5117 1.02 0.962,1.08 1209 11624
561 Symptoms involving digestive system digestive Both 0.7762 0.996 0.97,1.02 7750 22039 0.182 0.968 0.922,1.02 1888 15581
561.1 Diarrhea digestive Both 0.8933 0.998 0.969,1.03 5986 22042 0.7447 0.995 0.963,1.03 4673 18304
561.2 Flatulence digestive Both 0.2193 0.973 0.932,1.02 2358 18995 0.182 0.968 0.922,1.02 1888 15581
562 Diverticulosis and diverticulitis digestive Both 0.1271 0.975 0.945,1.01 5014 18500 0.3281 0.967 0.906,1.03 973 9531
562.1 Diverticulosis digestive Both 0.1521 0.977 0.946,1.01 4973 18448 0.3656 0.983 0.947,1.02 3582 14852
562.2 Diverticulitis digestive Both 0.2404 0.966 0.912,1.02 1292 12242 0.3281 0.967 0.906,1.03 973 9531
563 Constipation digestive Both 0.6653 0.993 0.964,1.02 5639 22004 0.8954 0.998 0.965,1.03 4394 18269
564 Functional digestive disorders digestive Both 0.811 0.997 0.973,1.02 9553 22037 0.3365 0.973 0.921,1.03 1392 13383
564.1 Irritable Bowel Syndrome digestive Both 0.6501 0.991 0.951,1.03 2751 17147 0.7129 0.992 0.949,1.04 2303 14300
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.8892 1.0 0.961,1.05 2348 18710 0.3034 1.03 0.977,1.08 1861 15215
564.9 Personal history of diseases of digestive system digestive Both 0.2143 0.969 0.923,1.02 1762 16521 0.3365 0.973 0.921,1.03 1392 13383
565 Anal and rectal conditions digestive Both 0.03802 0.957 0.919,0.998 2533 24500 0.246 0.954 0.881,1.03 678 7078
565.1 Anal and rectal polyp digestive Both 0.1884 0.956 0.893,1.02 932 9300 0.246 0.954 0.881,1.03 678 7078
567 Peritonitis and retroperitoneal infections digestive Both 0.134 0.954 0.897,1.01 1149 11482 0.1734 0.954 0.892,1.02 962 9176
568 Other disorders of peritoneum digestive Both 0.5998 0.986 0.934,1.04 1452 14494 0.4786 1.03 0.957,1.1 920 8532
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.7063 0.988 0.928,1.05 1076 10752 0.4786 1.03 0.957,1.1 920 8532
569 Other disorders of intestine digestive Both 0.03548 0.971 0.945,0.998 6343 29512 0.4656 0.976 0.915,1.04 1014 9661
569.1 Toxic gastroenteritis and colitis digestive Both 0.3908 1.06 0.932,1.2 251 2510 0.8128 1.02 0.879,1.18 190 2003
569.2 Gastrointestinal complications digestive Both 0.09772 0.951 0.896,1.01 1206 12058 0.4656 0.976 0.915,1.04 1014 9661
571 Chronic liver disease and cirrhosis digestive Both 0.5 1.01 0.978,1.05 3603 27394 0.9528 1.0 0.9,1.12 360 3469
571.5 Other chronic nonalcoholic liver disease digestive Both 0.4266 1.01 0.979,1.05 3388 27100 0.6546 1.02 0.939,1.11 629 6182
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.7482 0.988 0.917,1.06 781 7802 0.6546 1.02 0.939,1.11 629 6182
571.6 Primary biliary cirrhosis digestive Both 0.1318 0.878 0.741,1.04 146 1460 0.134 0.868 0.721,1.04 126 1198
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.2 0.952 0.882,1.03 749 7472 0.9528 1.0 0.9,1.12 360 3469
571.81 Portal hypertension digestive Both 0.3373 0.953 0.863,1.05 441 4400 0.9528 1.0 0.9,1.12 360 3469
572 Ascites (non malignant) digestive Both 0.8166 0.994 0.948,1.04 1884 18805 0.5284 1.02 0.965,1.07 1520 15113
573 Other disorders of liver digestive Both 0.4645 1.01 0.98,1.04 4460 28151 0.4688 1.02 0.975,1.06 2542 22919
573.1 Chronic passive congestion of liver digestive Both 0.1403 1.16 0.952,1.41 100 991 0.04786 1.24 1.0,1.54 82 809
573.2 Liver replaced by transplant digestive Both 0.1991 0.912 0.792,1.05 227 2268 0.5728 0.953 0.808,1.13 159 1810
573.3 Hepatomegaly digestive Both 0.1384 1.09 0.974,1.21 337 3368 0.4477 1.05 0.929,1.18 271 2757
573.4 Acute and subacute necrosis of liver digestive Both 0.4539 1.05 0.925,1.19 258 2580 0.4775 1.05 0.915,1.21 208 2098
573.5 Jaundice (not of newborn) digestive Both 0.9683 1.0 0.93,1.08 758 7555 0.9954 1.0 0.918,1.09 579 5978
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.05623 1.05 0.999,1.1 1973 19683 0.1279 1.04 0.988,1.1 1507 15908
573.7 Abnormal results of function study of liver digestive Both 0.3373 1.02 0.977,1.07 2110 21014 0.3639 1.02 0.973,1.08 1661 16882
573.9 Abnormal serum enzyme levels digestive Both 0.1374 1.03 0.991,1.06 3345 28043 0.4688 1.02 0.975,1.06 2542 22919
574 Cholelithiasis and cholecystitis digestive Both 0.4519 1.02 0.976,1.06 2610 25589 0.7745 1.01 0.928,1.11 553 5338
574.1 Cholelithiasis digestive Both 0.4198 1.02 0.976,1.06 2391 23829 0.2432 0.937 0.84,1.05 378 3614
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.2307 0.925 0.815,1.05 260 2580 0.208 0.914 0.794,1.05 214 2055
574.12 Cholelithiasis with other cholecystitis digestive Both 0.1963 0.936 0.846,1.03 444 4434 0.2432 0.937 0.84,1.05 378 3614
574.2 Calculus of bile duct digestive Both 0.4467 1.03 0.954,1.11 696 6939 0.236 1.05 0.967,1.15 573 5612
574.3 Cholecystitis without cholelithiasis digestive Both 0.9099 1.0 0.928,1.09 667 6662 0.7745 1.01 0.928,1.11 553 5338
575 Other biliary tract disease digestive Both 0.4325 1.02 0.972,1.07 1868 18668 0.07413 1.16 0.986,1.37 144 1474
575.1 Cholangitis digestive Both 0.8091 1.01 0.904,1.14 310 3089 0.5781 1.04 0.911,1.18 249 2393
575.2 Obstruction of bile duct digestive Both 0.8241 0.99 0.906,1.08 530 5291 0.7112 1.02 0.923,1.13 430 4062
575.6 Cholesterolosis of gallbladder digestive Both 0.9661 0.997 0.856,1.16 168 1680 0.5916 1.05 0.89,1.23 141 1406
575.7 Other disorders of gallbladder digestive Both 0.1135 1.06 0.986,1.14 773 7719 0.07244 1.08 0.994,1.16 642 6256
575.8 Other disorders of biliary tract digestive Both 0.4989 0.978 0.917,1.04 996 9950 0.9683 0.999 0.929,1.07 809 7757
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.0871 1.14 0.982,1.32 188 1880 0.07413 1.16 0.986,1.37 144 1474
577 Diseases of pancreas digestive Both 0.2123 0.97 0.925,1.02 1842 18379 0.8872 1.01 0.905,1.12 357 3438
577.1 Acute pancreatitis digestive Both 0.1303 0.95 0.89,1.02 967 9651 0.6194 0.982 0.913,1.06 792 7752
577.2 Chronic pancreatitis digestive Both 7.943E-4 0.833 0.749,0.927 396 3955 0.03388 0.882 0.786,0.99 328 3134
577.3 Cyst and pseudocyst of pancreas digestive Both 0.2582 0.946 0.86,1.04 462 4557 0.8872 1.01 0.905,1.12 357 3438
578 Gastrointestinal hemorrhage digestive Both 0.455 1.01 0.979,1.05 3572 30460 0.5689 1.02 0.953,1.09 925 9438
578.1 Hematemesis digestive Both 0.6516 0.976 0.879,1.08 383 3821 0.9661 0.998 0.89,1.12 317 3058
578.2 Blood in stool digestive Both 0.826 1.0 0.961,1.05 2156 21196 0.3548 1.02 0.974,1.08 1695 16887
578.8 Hemorrhage of rectum and anus digestive Both 0.5821 0.986 0.938,1.04 1718 17070 0.547 0.983 0.929,1.04 1344 13940
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.9863 1.0 0.944,1.06 1238 12280 0.5689 1.02 0.953,1.09 925 9438
579 Other symptoms involving abdomen and pelvis digestive Both 0.4335 1.01 0.98,1.05 3750 28690 0.01318 0.907 0.84,0.98 734 7627
579.2 Splenomegaly digestive Both 0.7852 1.01 0.93,1.1 593 5923 0.618 1.02 0.931,1.13 478 4839
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.01349 0.92 0.861,0.983 998 9882 0.01318 0.907 0.84,0.98 734 7627
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.1069 0.953 0.899,1.01 1264 12626 0.1687 0.906 0.788,1.04 222 2182
580.1 Glomerulonephritis genitourinary Both 0.9397 0.996 0.889,1.12 324 3228 0.4406 0.941 0.807,1.1 176 1864
580.11 Proliferative glomerulonephritis genitourinary Both 0.4508 1.07 0.891,1.3 114 1140 0.9099 1.01 0.817,1.26 88 957
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.4581 1.08 0.878,1.33 92 905 0.5998 1.06 0.842,1.35 72 759
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.811 0.984 0.862,1.12 232 2298 0.4406 0.941 0.807,1.1 176 1864
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.6427 1.04 0.889,1.21 167 1670 0.8995 1.01 0.847,1.21 129 1395
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.1531 0.952 0.89,1.02 943 9430 0.1202 0.919 0.827,1.02 376 3995
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.871 0.993 0.909,1.08 554 5535 0.2028 0.935 0.843,1.04 412 4326
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.2382 0.946 0.863,1.04 500 4995 0.1202 0.919 0.827,1.02 376 3995
580.4 Renal sclerosis, NOS genitourinary Both 0.2218 0.926 0.818,1.05 275 2750 0.1687 0.906 0.788,1.04 222 2182
585 Renal failure genitourinary Both 0.1766 0.98 0.952,1.01 5756 27307 0.3076 0.957 0.88,1.04 614 6285
585.1 Acute renal failure genitourinary Both 0.4036 0.984 0.949,1.02 3278 22851 0.6546 0.99 0.949,1.03 2487 18216
585.2 Renal failure NOS genitourinary Both 0.9162 0.996 0.921,1.08 688 6872 0.6699 0.98 0.896,1.07 517 5252
585.3 Chronic renal failure [CKD] genitourinary Both 0.2818 0.982 0.95,1.02 4216 24655 0.3162 0.954 0.871,1.05 524 5327
585.31 Renal dialysis genitourinary Both 0.4581 1.03 0.947,1.13 543 5430 0.7447 1.02 0.919,1.13 408 4392
585.32 End stage renal disease genitourinary Both 0.9462 0.997 0.926,1.07 773 7730 0.8072 0.989 0.908,1.08 579 6187
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.2851 0.976 0.934,1.02 2272 17155 0.6714 0.989 0.939,1.04 1672 13142
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.8166 0.991 0.917,1.07 707 7038 0.3162 0.954 0.871,1.05 524 5327
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.455 0.973 0.906,1.04 851 8381 0.3076 0.957 0.88,1.04 614 6285
586 Other disorders of the kidney and ureters genitourinary Both 0.2523 0.984 0.957,1.01 6202 28774 0.6839 0.988 0.932,1.05 1269 11522
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.7345 1.02 0.906,1.15 284 2825 0.9528 0.994 0.818,1.21 103 964
586.11 Small kidney genitourinary Both 0.4808 0.945 0.809,1.11 165 1642 0.7194 0.97 0.82,1.15 142 1325
586.12 Vesicoureteral reflux genitourinary Both 0.6353 1.05 0.868,1.26 112 1120 0.9528 0.994 0.818,1.21 103 964
586.2 Cyst of kidney, acquired genitourinary Both 0.6109 0.985 0.927,1.05 1170 11069 0.955 0.998 0.93,1.07 836 8276
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.4898 1.06 0.9,1.25 148 1470 0.8017 0.977 0.811,1.18 117 1149
586.4 Stricture/obstruction of ureter genitourinary Both 0.8395 0.995 0.944,1.05 1536 14675 0.6839 0.988 0.932,1.05 1269 11522
587 Kidney replaced by transpant genitourinary Both 0.7568 1.01 0.933,1.1 612 6120 0.867 0.991 0.897,1.1 427 4997
588 Disorders resulting from impaired renal function genitourinary Both 0.1172 0.939 0.868,1.02 701 7004 0.09772 0.915 0.824,1.02 401 4156
588.1 Renal osteodystrophy genitourinary Both 0.7834 1.02 0.89,1.17 227 2267 0.5754 0.952 0.802,1.13 150 1875
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.04786 0.912 0.832,0.999 525 5241 0.09772 0.915 0.824,1.02 401 4156
589 Abnormal results of function study of kidney genitourinary Both 0.5383 1.02 0.953,1.1 840 8370 0.6252 0.98 0.902,1.06 628 6447
590 Pyelonephritis genitourinary Both 0.8054 0.993 0.935,1.05 1161 11597 0.6138 0.983 0.92,1.05 952 9402
591 Urinary tract infection genitourinary Both 0.05012 0.975 0.95,1.0 8020 27291 0.413 0.988 0.961,1.02 6485 22138
592 Cystitis and urethritis genitourinary Both 0.6053 0.989 0.947,1.03 2264 19423 0.4093 0.922 0.761,1.12 122 1236
592.1 Cystitis genitourinary Both 0.7112 0.992 0.948,1.04 2149 18531 0.2104 1.08 0.96,1.2 306 2985
592.11 Acute cystitis genitourinary Both 0.2158 0.964 0.91,1.02 1256 12111 0.9931 1.0 0.937,1.07 996 9497
592.12 Chronic cystitis genitourinary Both 0.4159 1.06 0.92,1.22 199 1972 0.5728 1.05 0.891,1.23 151 1510
592.13 Chronic interstitial cystitis genitourinary Both 0.09333 1.1 0.985,1.22 354 3540 0.2104 1.08 0.96,1.2 306 2985
592.2 Urethritis and urethral syndrome genitourinary Both 0.4656 0.937 0.787,1.12 143 1430 0.4093 0.922 0.761,1.12 122 1236
593 Hematuria genitourinary Both 0.3882 0.985 0.952,1.02 3848 26566 0.6501 0.98 0.9,1.07 568 5662
593.1 Gross hematuria genitourinary Both 0.4764 0.979 0.923,1.04 1201 11351 0.5445 1.02 0.954,1.09 900 8466
593.2 Microscopic hematuria genitourinary Both 0.4055 0.968 0.897,1.04 724 7225 0.6501 0.98 0.9,1.07 568 5662
594 Urinary calculus genitourinary Both 0.526 1.01 0.981,1.04 5516 31876 0.5916 0.964 0.844,1.1 245 2390
594.1 Calculus of kidney genitourinary Both 0.5483 1.01 0.98,1.04 5155 31730 0.2094 1.02 0.988,1.05 4263 25784
594.2 Calculus of lower urinary tract genitourinary Both 0.4539 1.05 0.931,1.17 310 3068 0.1153 1.11 0.975,1.26 250 2306
594.3 Calculus of ureter genitourinary Both 0.8279 0.993 0.934,1.06 1104 11000 0.7568 1.01 0.945,1.08 925 8775
594.8 Renal colic genitourinary Both 0.673 0.974 0.861,1.1 286 2851 0.5916 0.964 0.844,1.1 245 2390
595 Hydronephrosis genitourinary Both 0.4046 1.02 0.969,1.08 1410 14092 0.8551 1.01 0.947,1.07 1168 11064
596 Other disorders of bladder genitourinary Both 0.05012 0.96 0.921,1.0 2527 23338 0.6577 0.986 0.927,1.05 1100 10675
596.1 Bladder neck obstruction genitourinary Both 0.07413 0.902 0.805,1.01 333 3288 0.06918 0.883 0.772,1.01 248 2302
596.5 Functional disorders of bladder genitourinary Both 0.309 0.972 0.919,1.03 1368 13608 0.6577 0.986 0.927,1.05 1100 10675
597 Other disorders of urethra and urinary tract genitourinary Both 0.04467 0.936 0.877,0.998 1041 10322 0.6561 0.963 0.815,1.14 145 1249
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.1607 0.941 0.863,1.02 608 6024 0.6252 0.977 0.888,1.07 493 4481
597.2 Urinary complications NEC genitourinary Both 0.3715 0.969 0.903,1.04 861 8600 0.9931 1.0 0.924,1.08 681 6552
597.8 Urethral hypermobility/ISD genitourinary Both 0.2618 0.911 0.775,1.07 158 1578 0.6561 0.963 0.815,1.14 145 1249
598 Abnormal findings on examination of urine genitourinary Both 0.7096 0.989 0.934,1.05 1263 12596 0.4775 0.976 0.914,1.04 957 9561
598.4 Other cells and casts in urine genitourinary Both 0.1722 1.16 0.939,1.42 91 906 0.05012 1.27 1.0,1.63 63 689
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.6383 0.986 0.931,1.05 1234 12317 0.4775 0.976 0.914,1.04 957 9561
599 Other symptoms/disorders or the urinary system genitourinary Both 0.1033 0.981 0.959,1.0 11346 25364 0.4406 0.981 0.935,1.03 1848 15977
599.1 Urinary obstruction genitourinary Both 0.5875 0.977 0.897,1.06 580 5634 0.0537 0.905 0.818,1.0 430 4023
599.2 Retention of urine genitourinary Both 0.04074 0.966 0.934,0.999 4234 24058 0.08318 0.967 0.931,1.0 3298 19454
599.3 Dysuria genitourinary Both 0.1982 0.977 0.942,1.01 3426 23180 0.3846 0.982 0.944,1.02 2762 18700
599.4 Urinary incontinence genitourinary Both 0.2051 0.979 0.948,1.01 4566 22567 0.5585 0.989 0.955,1.03 3703 18053
599.5 Frequency of urination and polyuria genitourinary Both 0.1406 0.975 0.944,1.01 4277 23742 0.3228 0.982 0.946,1.02 3410 19151
599.6 Oliguria and anuria genitourinary Both 0.08318 1.08 0.989,1.18 513 5104 0.1227 1.08 0.978,1.2 396 3788
599.7 Urethral discharge genitourinary Both 0.9727 1.0 0.808,1.25 83 830 0.3873 1.11 0.875,1.41 67 620
599.8 Other symptoms involving urinary system genitourinary Both 0.3614 0.985 0.953,1.02 4366 23262 0.863 0.997 0.961,1.03 3493 18691
599.9 Other abnormality of urination genitourinary Both 0.2911 0.977 0.936,1.02 2349 20289 0.4406 0.981 0.935,1.03 1848 15977
600 Hyperplasia of prostate genitourinary Male 0.1758 0.971 0.931,1.01 3315 9437 0.1945 0.967 0.919,1.02 2302 7240
601 Inflammatory diseases of prostate genitourinary Male 0.07762 0.936 0.87,1.01 825 7745 0.1 0.826 0.658,1.04 92 929
601.1 Prostatitis genitourinary Male 0.02754 0.885 0.793,0.987 378 3680 0.881 1.02 0.777,1.34 57 545
601.11 Acute prostatitis genitourinary Male 0.2624 0.883 0.711,1.1 95 933 0.1486 0.826 0.636,1.07 69 705
601.12 Chronic prostatitis genitourinary Male 0.7413 0.961 0.761,1.21 76 757 0.881 1.02 0.777,1.34 57 545
601.3 Orchitis and epididymitis genitourinary Male 0.9311 0.995 0.883,1.12 303 3008 0.3565 1.06 0.932,1.22 242 2424
601.4 Balanoposthitis genitourinary Male 0.9462 0.993 0.805,1.22 103 1019 0.8995 1.02 0.799,1.29 81 728
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.09333 0.851 0.705,1.03 125 1226 0.1 0.826 0.658,1.04 92 929
602 Other disorders of prostate genitourinary Male 0.2438 0.929 0.82,1.05 277 2673 0.1104 0.882 0.756,1.03 189 1849
603 Other disorders of testis genitourinary Male 0.3758 0.95 0.849,1.06 348 3468 0.8453 0.979 0.792,1.21 98 985
603.1 Hydrocele genitourinary Male 0.5943 0.964 0.841,1.1 229 2281 0.5433 0.953 0.815,1.11 181 1681
603.2 Spermatocele genitourinary Male 0.798 0.976 0.811,1.17 126 1258 0.8453 0.979 0.792,1.21 98 985
604 Disorders of penis genitourinary Male 0.04074 0.91 0.831,0.996 536 5321 0.0871 0.861 0.725,1.02 148 1310
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.02089 0.801 0.663,0.967 130 1297 0.06457 0.823 0.669,1.01 108 931
604.3 Peyronie's disease genitourinary Male 0.1 0.875 0.746,1.03 171 1703 0.0871 0.861 0.725,1.02 148 1310
605 Erectile dysfunction [ED] genitourinary Male 0.003236 0.938 0.899,0.979 2844 10666 0.00302 0.929 0.885,0.975 2213 8264
608 Other disorders of male genital organs genitourinary Male 0.4446 0.978 0.923,1.04 1302 11530 0.3467 0.969 0.907,1.03 1015 9120
609 Male infertility and abnormal spermatozoa genitourinary Male 0.5284 1.04 0.928,1.16 335 3350 0.1288 1.17 0.956,1.43 98 964
609.1 Infertility, male genitourinary Male 0.9886 1.0 0.878,1.14 242 2420 0.8299 0.973 0.76,1.25 74 716
609.11 Azoospermia and oligospermia genitourinary Male 0.6966 0.954 0.751,1.21 79 789 0.8299 0.973 0.76,1.25 74 716
609.2 Abnormal spermatozoa genitourinary Male 0.6998 1.04 0.862,1.25 119 1185 0.1288 1.17 0.956,1.43 98 964
610 Benign mammary dysplasias genitourinary Female 0.3304 0.981 0.943,1.02 3089 13905 0.547 0.978 0.911,1.05 813 8495
610.1 Cystic mastopathy genitourinary Female 0.6012 0.985 0.931,1.04 1361 12011 0.3882 0.973 0.913,1.04 1055 10065
610.4 Benign neoplasm of breast genitourinary Female 0.2761 0.976 0.935,1.02 2400 13828 0.3055 0.976 0.93,1.02 1982 11801
610.8 Other specified benign mammary dysplasias genitourinary Female 0.8091 0.992 0.931,1.06 1047 10149 0.547 0.978 0.911,1.05 813 8495
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.01175 0.959 0.929,0.991 4952 15509 0.06918 0.96 0.92,1.0 2405 13050
611.1 Abnormal mammogram genitourinary Both 0.02951 0.961 0.928,0.996 4074 13538 0.317 0.963 0.893,1.04 747 7446
611.11 Mammographic microcalcification genitourinary Both 0.4111 0.973 0.91,1.04 962 9131 0.317 0.963 0.893,1.04 747 7446
611.3 Lump or mass in breast genitourinary Both 0.02042 0.955 0.918,0.993 3011 15449 0.06918 0.96 0.92,1.0 2405 13050
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.0912 0.941 0.877,1.01 879 8768 0.2799 0.953 0.874,1.04 577 5691
612.1 Galactorrhea genitourinary Both 0.5728 1.06 0.875,1.27 109 1083 0.4036 1.09 0.893,1.32 96 978
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.0955 0.934 0.861,1.01 672 6710 0.2799 0.953 0.874,1.04 577 5691
612.3 Congenital anomalies of breast genitourinary Both 0.03981 0.765 0.592,0.988 70 676 ,
613 Other nonmalignant breast conditions genitourinary Both 0.06166 0.964 0.929,1.0 3180 18154 0.09333 0.945 0.884,1.01 955 9778
613.1 Inflammatory disease of breast genitourinary Both 0.6683 0.98 0.894,1.07 504 5035 0.4853 0.965 0.874,1.07 425 4317
613.5 Mastodynia genitourinary Both 0.04365 0.943 0.891,0.998 1313 12942 0.006761 0.916 0.86,0.976 1061 10902
613.7 Other signs and symptoms in breast genitourinary Both 0.9727 0.999 0.926,1.08 722 7109 0.5483 0.975 0.896,1.06 593 5993
613.8 Other specified disorders of breast genitourinary Both 0.7638 0.989 0.921,1.06 800 7961 0.547 0.976 0.902,1.06 661 6760
613.9 Breast disorder NOS genitourinary Both 0.06026 0.945 0.89,1.0 1211 11947 0.09333 0.945 0.884,1.01 955 9778
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.5768 1.01 0.973,1.05 2990 16271 0.7745 1.03 0.86,1.22 135 1380
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.873 0.99 0.873,1.12 267 2670 0.859 1.01 0.888,1.15 241 2282
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.7889 0.986 0.891,1.09 404 4024 0.5728 0.957 0.82,1.12 174 1722
614.31 Acute inflammatory pelvic disease genitourinary Female 0.9954 0.999 0.79,1.27 74 720 0.7464 0.959 0.746,1.23 65 649
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.5848 1.05 0.891,1.23 167 1666 0.6531 1.04 0.878,1.23 150 1424
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.9078 0.992 0.858,1.15 198 1979 0.5728 0.957 0.82,1.12 174 1722
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.5675 1.05 0.884,1.25 129 1290 0.561 1.06 0.88,1.26 120 1151
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.507 1.01 0.973,1.06 2546 16112 0.7745 1.03 0.86,1.22 135 1380
614.51 Cervicitis and endocervicitis genitourinary Female 0.8974 0.99 0.855,1.15 197 1970 0.9333 0.994 0.852,1.16 181 1699
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.2415 1.03 0.982,1.07 2201 15690 0.5047 1.02 0.969,1.07 1876 13224
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.03981 0.806 0.656,0.99 104 1040 0.1306 0.847 0.682,1.05 88 895
614.54 Abscess or ulceration of vulva genitourinary Female 0.2951 1.09 0.928,1.28 164 1619 0.7745 1.03 0.86,1.22 135 1380
615 Endometriosis genitourinary Female 0.6252 1.01 0.958,1.07 1298 12230 0.7745 1.01 0.95,1.07 1143 10485
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.1581 0.961 0.91,1.02 1415 13522 0.2723 0.968 0.913,1.03 1227 11655
618 Genital prolapse genitourinary Female 0.4786 0.982 0.934,1.03 1707 14626 0.2393 1.07 0.956,1.2 321 2998
618.1 Prolapse of vaginal walls genitourinary Female 0.7568 0.991 0.934,1.05 1179 11187 0.871 1.01 0.943,1.07 987 8946
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.3926 1.04 0.948,1.15 444 4418 0.1849 1.07 0.967,1.19 356 3498
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.826 1.01 0.898,1.14 286 2855 0.561 1.04 0.912,1.18 240 2214
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.2649 1.06 0.956,1.18 375 3750 0.2393 1.07 0.956,1.2 321 2998
619 Noninflammatory female genital disorders genitourinary Female 0.4656 1.01 0.98,1.05 4598 15534 0.2371 0.955 0.884,1.03 715 7624
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.5916 1.02 0.959,1.08 1262 11294 0.2748 1.03 0.973,1.1 1125 9718
619.2 Disorders of uterus, NEC genitourinary Female 0.4603 1.04 0.942,1.14 444 4435 0.3656 1.05 0.945,1.16 379 3832
619.3 Noninflammatory disorders of cervix genitourinary Female 0.875 0.992 0.894,1.1 391 3892 0.9931 1.0 0.896,1.12 346 3354
619.4 Noninflammatory disorders of vagina genitourinary Female 0.9268 0.998 0.951,1.05 1903 15019 0.9727 0.999 0.949,1.05 1621 12665
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.9226 0.997 0.931,1.07 914 9082 0.2371 0.955 0.884,1.03 715 7624
620 Dysplasia of female genital organs genitourinary Female 0.3606 1.05 0.943,1.17 325 3234 0.9204 1.01 0.843,1.21 128 1287
620.1 Dysplasia of cervix genitourinary Female 0.4345 1.07 0.903,1.27 142 1420 0.9204 1.01 0.843,1.21 128 1287
621 Endometrial hyperplasia genitourinary Female 0.2884 0.94 0.838,1.05 334 3335 0.369 0.945 0.837,1.07 289 2764
622 Polyp of female genital organs genitourinary Female 0.1706 0.959 0.903,1.02 1191 11723 0.6683 0.973 0.86,1.1 270 2916
622.1 Polyp of corpus uteri genitourinary Female 0.2328 0.96 0.897,1.03 949 9362 0.2163 0.955 0.888,1.03 807 7846
622.2 Mucous polyp of cervix genitourinary Female 0.9705 0.998 0.895,1.11 348 3480 0.6683 0.973 0.86,1.1 270 2916
623 Hypertrophy of female genital organs genitourinary Female 0.9036 0.995 0.915,1.08 605 6003 0.507 0.969 0.882,1.06 480 5085
624 Symptoms involving female genital tract genitourinary Female 0.6295 0.984 0.922,1.05 1013 9695 0.5572 1.02 0.962,1.08 1344 10615
624.1 Dystrophy of female genital tract genitourinary Female 0.3258 1.08 0.926,1.26 168 1680 0.3304 1.09 0.916,1.3 131 1359
624.9 stress incontinence, female genitourinary Female 0.4677 1.02 0.968,1.07 1549 12918 0.5572 1.02 0.962,1.08 1344 10615
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.4406 0.987 0.955,1.02 4618 14394 0.5508 0.979 0.914,1.05 892 8688
625.1 Dyspareunia genitourinary Female 0.3062 0.967 0.906,1.03 1011 10081 0.5508 0.979 0.914,1.05 892 8688
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.8453 1.0 0.97,1.04 4726 13065 0.7447 1.01 0.931,1.1 581 4649
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.9772 0.999 0.962,1.04 3426 12112 0.9931 1.0 0.888,1.13 284 2705
626.11 Absent or infrequent menstruation genitourinary Female 0.5212 0.976 0.907,1.05 802 6948 0.4898 0.973 0.902,1.05 735 6185
626.12 Excessive or frequent menstruation genitourinary Female 0.7396 0.991 0.942,1.04 1703 9843 0.9226 1.0 0.95,1.06 1546 8556
626.13 Irregular menstrual cycle genitourinary Female 0.6166 1.01 0.961,1.07 1543 10197 0.9817 1.0 0.946,1.06 1378 8841
626.14 Irregular menstrual bleeding genitourinary Female 0.4667 0.973 0.904,1.05 777 7408 0.673 0.984 0.911,1.06 710 6524
626.15 Infertility, female, associated with anovulation genitourinary Female 0.9572 0.997 0.887,1.12 300 3000 0.9931 1.0 0.888,1.13 284 2705
626.2 Dysmenorrhea genitourinary Female 0.1837 1.04 0.98,1.11 1116 8297 0.2239 1.04 0.976,1.11 1032 7297
626.4 Premenstrual tension syndromes genitourinary Female 0.4688 1.05 0.925,1.18 275 2741 0.3864 1.06 0.931,1.2 250 2399
626.8 Infertility, female genitourinary Female 0.9817 0.999 0.92,1.09 630 5218 0.7447 1.01 0.931,1.1 581 4649
627 Menopausal and postmenopausal disorders genitourinary Female 0.0871 0.968 0.933,1.0 3657 12296 0.2415 0.919 0.797,1.06 206 2030
627.1 Postmenopausal bleeding genitourinary Female 0.618 0.983 0.92,1.05 957 8768 0.7096 0.986 0.915,1.06 751 6969
627.2 Symptomatic menopause genitourinary Female 0.01 0.944 0.903,0.986 2443 11667 0.6026 0.965 0.843,1.1 227 2331
627.21 Symptomatic artificial menopause genitourinary Female 0.1535 0.869 0.716,1.05 125 1241 0.5129 0.932 0.754,1.15 102 1040
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.4909 0.959 0.851,1.08 295 2948 0.6026 0.965 0.843,1.1 227 2331
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.9484 1.0 0.929,1.08 729 7262 0.8166 1.01 0.927,1.1 567 5755
627.4 Premenopausal menorrhagia genitourinary Female 0.8241 0.987 0.876,1.11 305 3020 0.9886 1.0 0.882,1.14 270 2580
627.5 Premature menopause and other ovarian failure genitourinary Female 0.2148 0.919 0.805,1.05 234 2340 0.2415 0.919 0.797,1.06 206 2030
628 Ovarian cyst genitourinary Female 0.9333 0.998 0.947,1.05 1619 11554 0.6902 1.01 0.957,1.07 1421 9809
634 Miscarriage; stillbirth pregnancy complications Female 0.5346 0.975 0.899,1.06 648 6413 0.7762 0.968 0.772,1.21 83 863
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.857 1.01 0.878,1.17 209 2090 0.877 1.01 0.875,1.17 196 1918
634.3 Ectopic pregnancy pregnancy complications Female 0.6561 0.953 0.771,1.18 95 950 0.7762 0.968 0.772,1.21 83 863
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.9484 1.0 0.908,1.11 414 4070 0.4875 1.05 0.913,1.21 198 1917
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.6252 1.03 0.912,1.17 272 2720 0.5395 1.04 0.916,1.18 252 2513
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.6026 1.04 0.903,1.19 206 2060 0.4875 1.05 0.913,1.21 198 1917
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.9354 1.0 0.934,1.08 855 6402 0.2323 0.844 0.639,1.11 53 556
636.1 Threatened premature labor pregnancy complications Female 0.7328 0.98 0.87,1.1 298 2980 0.826 0.987 0.874,1.11 281 2761
636.2 Early onset of delivery pregnancy complications Female 0.8974 1.01 0.883,1.15 233 2330 0.8551 1.01 0.884,1.16 223 2154
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.5781 1.03 0.926,1.15 356 3556 0.5 1.04 0.93,1.16 337 3266
636.8 Cervical incompetence pregnancy complications Female 0.4246 0.898 0.69,1.17 60 600 0.2323 0.844 0.639,1.11 53 556
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.929 0.99 0.797,1.23 89 884 0.8872 1.02 0.803,1.29 75 761
638 Other high-risk pregnancy pregnancy complications Female 0.5649 1.02 0.95,1.1 818 5867 0.4426 1.03 0.956,1.11 769 5405
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.2163 0.938 0.848,1.04 421 4210 0.0912 0.877 0.753,1.02 197 1977
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.1274 0.893 0.772,1.03 215 2150 0.0912 0.877 0.753,1.02 197 1977
643 Excessive vomiting in pregnancy pregnancy complications Female 0.1127 1.13 0.972,1.3 181 1810 0.3565 1.11 0.891,1.38 82 800
643.1 Hyperemesis gravidarum pregnancy complications Female 0.4375 1.09 0.879,1.35 87 870 0.3565 1.11 0.891,1.38 82 800
644 Anemia during pregnancy pregnancy complications Female 0.2203 0.901 0.762,1.06 154 1540 0.3972 0.93 0.786,1.1 145 1448
645 Late pregnancy and failed induction pregnancy complications Female 0.2985 0.937 0.828,1.06 286 2860 0.3069 0.936 0.825,1.06 269 2656
646 Other complications of pregnancy NEC pregnancy complications Female 0.8433 0.992 0.912,1.08 622 5063 0.9484 0.997 0.916,1.09 598 4700
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.8375 1.02 0.862,1.2 152 1520 0.7674 1.02 0.879,1.19 173 1698
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.811 1.02 0.876,1.18 182 1820 0.7674 1.02 0.879,1.19 173 1698
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.8472 1.01 0.941,1.08 968 6387 0.2198 0.935 0.84,1.04 377 3709
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.0912 0.915 0.825,1.01 413 4130 0.2198 0.935 0.84,1.04 377 3709
650 Normal delivery pregnancy complications Female 0.6095 1.02 0.946,1.1 757 6412 0.5623 1.02 0.947,1.11 708 5900
651 Multiple gestation pregnancy complications Female 0.4477 1.09 0.878,1.34 100 1000 0.3083 1.12 0.902,1.38 95 899
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.7261 1.02 0.925,1.12 461 4586 0.6855 1.02 0.926,1.12 435 4199
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.4508 0.963 0.873,1.06 443 4189 0.7534 0.984 0.89,1.09 414 3880
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.389 1.04 0.95,1.14 482 4820 0.2128 1.11 0.943,1.3 151 1490
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.6194 1.03 0.927,1.14 402 4020 0.618 1.03 0.925,1.14 375 3690
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.5012 1.05 0.903,1.23 163 1630 0.2128 1.11 0.943,1.3 151 1490
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.4266 1.02 0.965,1.09 1244 8117 0.9462 1.0 0.909,1.11 424 4054
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.8872 0.993 0.901,1.09 451 4371 0.9462 1.0 0.909,1.11 424 4054
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.7413 1.02 0.896,1.17 246 2460 0.2143 1.09 0.951,1.25 212 2123
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.1432 1.23 0.933,1.61 59 590 ,
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.4426 1.06 0.916,1.22 195 1950 0.6295 1.04 0.891,1.21 174 1743
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.631 0.978 0.891,1.07 504 4732 0.9333 0.996 0.906,1.09 474 4363
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.4426 0.961 0.868,1.06 420 4080 0.4256 0.959 0.864,1.06 399 3801
665 Obstetrical/birth trauma pregnancy complications Female 0.7362 1.01 0.939,1.09 751 6161 0.9886 0.999 0.924,1.08 697 5644
669 Complications of labor and delivery NEC pregnancy complications Female 0.3451 0.962 0.887,1.04 671 5265 0.3281 0.96 0.883,1.04 635 4864
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.09333 0.87 0.739,1.02 172 1720 0.1799 0.889 0.748,1.06 147 1501
674 Other complications of the puerperium NEC pregnancy complications Female 0.9594 0.996 0.857,1.16 181 1810 0.5875 0.958 0.82,1.12 168 1670
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.118 0.856 0.705,1.04 122 1220 0.2056 0.878 0.718,1.07 112 1137
681 Superficial cellulitis and abscess dermatologic Both 0.1016 1.03 0.995,1.06 5078 31991 0.6918 0.987 0.924,1.05 986 10126
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.03715 1.08 1.0,1.15 862 8581 0.1919 1.05 0.974,1.14 651 7020
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.177 1.05 0.977,1.13 781 7775 0.3365 1.04 0.957,1.14 561 6409
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.06166 1.05 0.998,1.11 1533 15238 0.1496 1.05 0.984,1.11 1124 12221
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.0631 1.05 0.997,1.1 1649 16359 0.3381 1.03 0.971,1.09 1230 13076
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.4188 1.02 0.967,1.08 1291 12850 0.871 1.01 0.941,1.07 949 10252
681.7 Cellulitis and abscess of trunk dermatologic Both 0.7145 1.01 0.954,1.07 1238 12342 0.6918 0.987 0.924,1.05 986 10126
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.01905 1.06 1.01,1.11 1660 16466 0.5808 1.06 0.855,1.32 86 992
686.1 Carbuncle and furuncle dermatologic Both 0.2438 0.939 0.845,1.04 390 3881 0.1629 0.92 0.818,1.03 311 3256
686.2 Impetigo dermatologic Both 0.5093 1.04 0.926,1.17 310 3068 0.7499 1.02 0.89,1.18 214 2529
686.3 Pilonidal cyst dermatologic Both 0.7261 1.03 0.856,1.25 120 1200 0.6109 1.05 0.861,1.29 102 1058
686.4 Pyogenic granuloma dermatologic Both 0.547 1.06 0.879,1.28 121 1205 0.5808 1.06 0.855,1.32 86 992
687 Symptoms affecting skin dermatologic Both 0.5902 1.01 0.98,1.04 6119 25901 0.3112 0.983 0.95,1.02 4026 21396
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.5916 1.01 0.979,1.04 5371 25824 0.3963 0.985 0.953,1.02 4088 21633
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.6871 1.01 0.977,1.04 5264 25870 0.2143 0.978 0.945,1.01 3821 21680
687.3 Changes in skin texture dermatologic Both 0.1239 1.09 0.976,1.23 294 2926 0.542 1.04 0.91,1.2 210 2372
687.4 Disturbance of skin sensation dermatologic Both 0.4083 0.987 0.957,1.02 4942 25586 0.3112 0.983 0.95,1.02 4026 21396
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 1.0E-10 1.09 1.06,1.12 7192 31086 0.1225 1.03 0.993,1.06 4072 27107
690 Erythematosquamous dermatosis dermatologic Both 6.026E-4 1.06 1.03,1.1 3810 26256 0.9572 0.999 0.954,1.05 2022 21760
690.1 Seborrheic dermatitis dermatologic Both 6.607E-4 1.06 1.03,1.1 3802 26218 0.9572 0.999 0.954,1.05 2022 21760
691 Congenital anomalies of skin dermatologic Both 0.881 1.01 0.913,1.11 411 4110 0.9376 0.995 0.889,1.11 306 3530
694 Dyschromia and Vitiligo dermatologic Both 0.01549 1.07 1.01,1.13 1286 12819 0.2924 1.04 0.965,1.13 658 9570
694.1 Vitiligo dermatologic Both 0.1175 0.837 0.671,1.05 94 931 0.1026 0.805 0.62,1.04 69 779
694.2 Other dyschromia dermatologic Both 0.02089 1.07 1.01,1.14 1146 11421 0.2924 1.04 0.965,1.13 658 9570
694.3 Vascular disorders of skin dermatologic Both 0.04467 1.26 1.01,1.58 69 686 ,
695 Erythematous conditions dermatologic Both 0.1652 1.03 0.989,1.06 3180 24642 0.6998 1.02 0.921,1.13 379 4201
695.2 Bullous dermatoses dermatologic Both 0.7047 0.954 0.748,1.22 68 658 ,
695.3 Rosacea dermatologic Both 0.3698 1.03 0.971,1.08 1405 14019 0.9057 0.996 0.93,1.07 883 11592
695.4 Lupus (localized and systemic) dermatologic Both 0.246 0.949 0.87,1.04 556 5556 0.1183 0.924 0.836,1.02 436 4561
695.41 Cutaneous lupus erythematosus dermatologic Both 0.6427 0.966 0.834,1.12 196 1955 0.4217 0.936 0.796,1.1 160 1718
695.42 Systemic lupus erythematosus dermatologic Both 0.1718 0.939 0.858,1.03 530 5287 0.1183 0.924 0.836,1.02 436 4561
695.7 Prurigo and Lichen dermatologic Both 0.7129 1.02 0.924,1.12 429 4275 0.6397 1.03 0.916,1.15 294 3528
695.8 Other specified erythematous conditions dermatologic Both 0.1466 1.06 0.979,1.15 613 6111 0.3483 1.05 0.951,1.15 443 5124
695.9 Unspecified erythematous condition dermatologic Both 0.2234 1.06 0.967,1.15 513 5102 0.6998 1.02 0.921,1.13 379 4201
696 Psoriasis and related disorders dermatologic Both 0.03388 0.934 0.876,0.995 1080 10781 0.6368 0.964 0.829,1.12 181 1889
696.3 Pityriasis dermatologic Both 0.2032 0.844 0.649,1.1 64 640 0.3373 0.876 0.667,1.15 56 588
696.4 Psoriasis dermatologic Both 0.06166 0.939 0.88,1.0 1014 10115 0.6368 0.964 0.829,1.12 181 1889
696.41 Psoriasis vulgaris dermatologic Both 0.1614 0.952 0.889,1.02 918 9161 0.3228 0.961 0.889,1.04 696 7687
696.42 Psoriatic arthropathy dermatologic Both 0.4753 0.951 0.829,1.09 225 2250 0.6368 0.964 0.829,1.12 181 1889
697 Sarcoidosis dermatologic Both 0.3013 0.935 0.823,1.06 265 2650 0.6871 0.972 0.845,1.12 216 2190
698 Pruritus and related conditions dermatologic Both 0.4989 1.02 0.968,1.07 1686 16680 0.8913 0.996 0.942,1.05 1317 13733
700 Corns and callosities dermatologic Both 0.6561 0.983 0.913,1.06 764 7615 0.4864 0.969 0.887,1.06 541 6053
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.0912 1.02 0.996,1.05 5838 31889 0.8054 0.983 0.859,1.13 243 2695
701.1 Keratoderma, acquired dermatologic Both 0.9141 0.994 0.896,1.1 389 3845 0.631 0.969 0.851,1.1 245 3062
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.04898 1.05 1.0,1.1 1705 16953 0.9931 1.0 0.935,1.07 910 14175
701.3 Circumscribed scleroderma dermatologic Both 0.537 0.97 0.88,1.07 434 4334 0.3373 0.947 0.848,1.06 337 3619
701.4 Keloid scar dermatologic Both 0.0871 1.09 0.988,1.19 454 4503 0.857 0.989 0.874,1.12 265 3889
701.5 Abnormal granulation tissue dermatologic Both 0.9795 0.999 0.889,1.12 328 3260 0.8054 0.983 0.859,1.13 243 2695
702 Degenerative skin conditions and other dermatoses dermatologic Both 7.762E-8 1.08 1.05,1.12 5351 24908 0.6546 0.99 0.947,1.03 2193 21984
702.1 Actinic keratosis dermatologic Both 3.162E-23 1.2 1.16,1.25 3236 22206 1.905E-5 1.13 1.07,1.19 1341 18242
702.2 Seborrheic keratosis dermatologic Both 2.399E-4 1.06 1.03,1.1 4151 26248 0.6546 0.99 0.947,1.03 2193 21984
702.4 Degenerative skin disorders dermatologic Both 0.7798 0.964 0.747,1.24 63 624 ,
703 Diseases of nail, NOS dermatologic Both 0.879 1.0 0.943,1.07 1033 10222 0.7516 0.984 0.894,1.08 449 4724
703.1 Ingrowing nail dermatologic Both 0.9078 0.995 0.914,1.08 580 5773 0.7516 0.984 0.894,1.08 449 4724
704 Diseases of hair and hair follicles dermatologic Both 0.9397 1.0 0.96,1.05 2321 22718 0.4909 1.02 0.957,1.1 880 10631
704.1 Alopecia dermatologic Both 0.03236 0.933 0.875,0.994 1074 10601 0.05012 0.931 0.866,1.0 839 8933
704.11 Alopecia Areata dermatologic Both 0.4285 1.11 0.858,1.43 58 580 ,
704.2 Hirsutism dermatologic Both 0.6281 1.03 0.903,1.18 227 2263 0.6918 0.971 0.84,1.12 199 2005
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.07762 1.05 0.994,1.11 1286 12791 0.4909 1.02 0.957,1.1 880 10631
705 Disorders of sweat glands dermatologic Both 0.3589 0.955 0.865,1.05 439 4376 0.1986 0.949 0.875,1.03 662 7051
705.1 Dyshidrosis dermatologic Both 0.04898 0.823 0.678,0.999 114 1131 0.05129 0.812 0.658,1.0 96 979
705.3 Hidradenitis dermatologic Both 0.9638 1.0 0.86,1.17 183 1815 0.7079 1.03 0.877,1.21 161 1620
705.8 Hyperhidrosis dermatologic Both 0.5105 0.976 0.909,1.05 846 8429 0.1986 0.949 0.875,1.03 662 7051
706 Diseases of sebaceous glands dermatologic Both 0.0389 1.03 1.0,1.07 4454 32859 0.4416 0.969 0.894,1.05 627 8588
706.1 Acne dermatologic Both 0.3819 1.02 0.974,1.07 1931 17499 0.8414 1.01 0.953,1.06 1505 15228
706.2 Sebaceous cyst dermatologic Both 0.1236 1.04 0.991,1.08 2150 21106 0.4732 1.02 0.967,1.07 1494 17235
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.06457 1.06 0.997,1.12 1124 11122 0.4416 0.969 0.894,1.05 627 8588
707 Chronic ulcer of skin dermatologic Both 0.5483 0.987 0.944,1.03 2193 21811 0.875 0.995 0.934,1.06 1031 10607
707.1 Decubitus ulcer dermatologic Both 0.9016 0.995 0.915,1.08 600 5984 0.4667 1.04 0.942,1.14 459 4608
707.2 Chronic ulcer of leg or foot dermatologic Both 0.1991 1.05 0.975,1.13 721 7166 0.859 1.01 0.924,1.1 535 5520
707.3 Chronic ulcer of unspecified site dermatologic Both 0.7925 0.992 0.938,1.05 1339 13370 0.875 0.995 0.934,1.06 1031 10607
709 Diffuse diseases of connective tissue dermatologic Both 0.04467 0.937 0.88,0.998 1086 10825 0.2553 0.95 0.87,1.04 540 5606
709.2 Sicca syndrome dermatologic Both 0.4436 0.958 0.859,1.07 365 3650 0.3459 0.944 0.836,1.06 295 3100
709.3 Systemic sclerosis dermatologic Both 0.3467 0.928 0.795,1.08 184 1840 0.2104 0.897 0.756,1.06 153 1564
709.5 Dermatomyositis dermatologic Both 0.3681 0.895 0.704,1.14 70 700 0.278 0.865 0.666,1.12 60 581
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.9441 1.01 0.801,1.27 78 780 0.6427 0.944 0.74,1.2 69 690
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.1413 0.941 0.868,1.02 659 6563 0.2553 0.95 0.87,1.04 540 5606
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.0955 1.03 0.996,1.06 5120 27320 0.2094 1.02 0.988,1.06 3794 23225
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.5408 0.922 0.71,1.2 64 626 ,
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.08128 1.06 0.993,1.13 954 9524 0.3319 1.04 0.961,1.12 694 6832
710.1 Osteomyelitis musculoskeletal Both 0.1202 1.05 0.986,1.13 914 9127 0.3319 1.04 0.961,1.12 694 6832
710.11 Acute osteomyelitis musculoskeletal Both 0.456 1.04 0.941,1.15 425 4234 0.6823 1.02 0.915,1.15 332 3333
710.12 Chronic osteomyelitis musculoskeletal Both 0.1476 1.08 0.973,1.2 378 3758 0.1151 1.1 0.978,1.23 306 3032
710.19 Unspecified osteomyelitis musculoskeletal Both 0.3491 1.03 0.964,1.11 867 8656 0.3319 1.04 0.961,1.12 694 6832
711 Arthropathy associated with infections musculoskeletal Both 0.8356 0.988 0.88,1.11 314 3124 0.8433 0.984 0.843,1.15 179 1739
711.1 Pyogenic arthritis musculoskeletal Both 0.8831 0.99 0.862,1.14 223 2206 0.8433 0.984 0.843,1.15 179 1739
712 Infective connective tissue disorders musculoskeletal Both 0.09772 1.15 0.974,1.37 136 1360 0.1795 1.14 0.94,1.39 109 1088
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.415 0.943 0.82,1.09 222 2214 0.7551 0.966 0.78,1.2 87 938
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.3784 0.918 0.759,1.11 118 1180 0.7551 0.966 0.78,1.2 87 938
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.7656 0.992 0.943,1.04 1649 14662 0.873 0.995 0.934,1.06 1061 9725
714.1 Rheumatoid arthritis musculoskeletal Both 0.4977 0.981 0.927,1.04 1342 12332 0.873 0.995 0.934,1.06 1061 9725
715 Other inflammatory spondylopathies musculoskeletal Both 0.6471 0.985 0.922,1.05 979 9761 0.798 0.978 0.827,1.16 152 1391
715.1 Sacroiliitis NEC musculoskeletal Both 0.8241 0.984 0.855,1.13 212 2120 0.537 0.953 0.817,1.11 176 1720
715.2 Ankylosing spondylitis musculoskeletal Both 0.9226 1.01 0.864,1.18 177 1760 0.798 0.978 0.827,1.16 152 1391
716 Other arthropathies musculoskeletal Both 0.413 0.99 0.968,1.01 10893 26011 0.6081 1.01 0.981,1.03 8437 21528
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.8072 0.98 0.835,1.15 155 1540 0.3589 0.919 0.767,1.1 125 1232
716.2 Unspecified monoarthritis musculoskeletal Both 0.9247 0.991 0.821,1.2 116 1156 0.2477 1.13 0.921,1.37 98 891
716.9 Arthropathy NOS musculoskeletal Both 0.3648 0.989 0.967,1.01 10831 26002 0.6081 1.01 0.981,1.03 8437 21528
717 Polymyalgia Rheumatica musculoskeletal Both 0.3243 0.931 0.808,1.07 210 2061 0.07943 0.857 0.722,1.02 149 1411
720 Spinal stenosis musculoskeletal Both 0.6622 0.992 0.956,1.03 3298 24117 0.4887 1.02 0.97,1.07 1892 15772
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.7727 0.994 0.953,1.04 2415 20454 0.4887 1.02 0.97,1.07 1892 15772
721 Spondylosis and allied disorders musculoskeletal Both 0.9528 1.0 0.97,1.03 4494 27007 0.7852 0.979 0.841,1.14 176 1613
721.1 Spondylosis without myelopathy musculoskeletal Both 0.8531 1.0 0.971,1.04 4206 26584 0.3776 1.02 0.98,1.05 3327 21275
721.2 Spondylosis with myelopathy musculoskeletal Both 0.6368 0.982 0.91,1.06 740 7398 0.5943 1.02 0.941,1.11 613 5671
721.8 Other allied disorders of spine musculoskeletal Both 0.4285 0.945 0.823,1.09 212 2099 0.7852 0.979 0.841,1.14 176 1613
722 Intervertebral disc disorders musculoskeletal Both 0.3436 0.986 0.957,1.02 5242 28702 0.2477 0.966 0.912,1.02 1299 12558
722.1 Displacement of intervertebral disc musculoskeletal Both 0.4775 0.986 0.95,1.02 3038 26827 0.9183 0.998 0.957,1.04 2501 21680
722.3 Schmorl's nodes musculoskeletal Both 0.2891 0.895 0.73,1.1 115 1140 0.5383 0.933 0.749,1.16 99 905
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.7031 0.993 0.958,1.03 3338 26140 0.4909 1.01 0.974,1.06 2664 20862
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.9036 1.01 0.915,1.11 464 4634 0.537 1.03 0.932,1.15 386 3655
722.8 Postlaminectomy syndrome musculoskeletal Both 0.3311 1.06 0.946,1.18 336 3360 0.3758 1.06 0.936,1.19 279 2650
722.9 Other and unspecified disc disorder musculoskeletal Both 0.1172 0.959 0.91,1.01 1569 15676 0.2477 0.966 0.912,1.02 1299 12558
723 Other disorders of cervical region musculoskeletal Both 0.5248 0.976 0.906,1.05 761 7610 0.2483 1.11 0.931,1.32 128 1510
723.1 Torticollis musculoskeletal Both 0.3837 1.07 0.922,1.24 187 1870 0.2483 1.11 0.931,1.32 128 1510
724 Other and unspecified disorders of back musculoskeletal Both 0.6237 0.991 0.956,1.03 3338 26730 0.5047 1.02 0.959,1.09 1024 9770
724.1 Disorders of sacrum musculoskeletal Both 0.177 0.967 0.921,1.02 1804 17663 0.3819 0.976 0.925,1.03 1471 14276
724.2 Disorders of coccyx musculoskeletal Both 0.4467 0.957 0.854,1.07 331 3290 0.743 0.979 0.863,1.11 265 2718
724.8 Other symptoms referable to back musculoskeletal Both 0.5117 0.975 0.904,1.05 753 7499 0.5383 0.975 0.898,1.06 644 6005
724.9 Other unspecified back disorders musculoskeletal Both 0.3873 1.03 0.968,1.09 1246 12418 0.5047 1.02 0.959,1.09 1024 9770
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.2944 0.986 0.961,1.01 7682 25455 0.236 0.954 0.883,1.03 711 7074
726.1 Enthesopathy musculoskeletal Both 0.04169 0.971 0.943,0.999 5795 25454 0.1245 0.975 0.945,1.01 4707 20816
726.2 Synoviopathy musculoskeletal Both 0.342 0.965 0.896,1.04 774 7723 0.561 0.976 0.899,1.06 626 6195
726.3 Bursitis musculoskeletal Both 0.6871 0.988 0.934,1.05 1339 13090 0.5105 0.979 0.919,1.04 1069 10468
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.2716 0.962 0.897,1.03 889 8846 0.236 0.954 0.883,1.03 711 7074
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.9376 0.999 0.97,1.03 5811 25457 0.2355 1.13 0.925,1.38 105 1005
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.3597 0.98 0.939,1.02 2342 20541 0.6012 0.987 0.942,1.04 1912 16738
727.2 Bursitis disorders musculoskeletal Both 0.9661 0.998 0.892,1.12 341 3381 0.7396 1.02 0.9,1.16 266 2630
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.1936 1.04 0.98,1.11 1109 11034 0.2042 1.05 0.976,1.12 880 8927
727.5 Rupture of synovium musculoskeletal Both 0.5754 1.03 0.926,1.15 376 3718 0.3443 1.06 0.94,1.19 298 2956
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.1208 0.963 0.918,1.01 1927 18092 0.3243 0.973 0.923,1.03 1509 14121
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.5834 1.03 0.938,1.12 520 5187 0.6486 1.02 0.928,1.13 429 4389
727.8 Plica syndrome musculoskeletal Both 0.3758 1.09 0.902,1.31 115 1117 0.2355 1.13 0.925,1.38 105 1005
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.6353 0.991 0.957,1.03 3433 24951 0.02138 0.85 0.74,0.976 233 2368
728.1 Muscular calcification and ossification musculoskeletal Both 0.9247 1.01 0.804,1.27 69 682 0.9705 0.995 0.775,1.28 57 566
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.7709 0.98 0.855,1.12 230 2298 0.4539 0.942 0.806,1.1 176 1862
728.7 Fasciitis musculoskeletal Both 0.3698 0.979 0.936,1.03 2056 19042 0.02138 0.85 0.74,0.976 233 2368
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.2323 0.931 0.828,1.05 310 3095 0.02138 0.85 0.74,0.976 233 2368
729 Other disorders of soft tissues musculoskeletal Both 0.8414 1.0 0.964,1.05 2618 22751 0.9795 0.997 0.799,1.24 78 823
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.6067 0.935 0.726,1.21 63 630 0.7943 0.966 0.743,1.25 58 503
729.3 Panniculitis musculoskeletal Both 0.863 0.983 0.806,1.2 100 1000 0.9795 0.997 0.799,1.24 78 823
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.7447 0.953 0.716,1.27 53 530 ,
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.9376 0.993 0.834,1.18 145 1441 0.6339 1.05 0.858,1.29 105 1108
732 Osteochondropathies musculoskeletal Both 0.7278 1.02 0.903,1.16 289 2882 0.9886 1.0 0.775,1.3 68 631
732.1 Juvenile osteochondrosis musculoskeletal Both 0.7762 0.976 0.828,1.15 157 1570 0.8054 1.02 0.859,1.22 141 1364
732.7 Osteochondritis dissecans musculoskeletal Both 0.7656 0.962 0.745,1.24 71 710 0.9886 1.0 0.775,1.3 68 631
733 Other disorders of bone and cartilage musculoskeletal Both 0.2061 0.977 0.942,1.01 3481 21966 0.6714 1.05 0.838,1.32 75 729
733.2 Cyst of bone musculoskeletal Both 0.6166 0.96 0.82,1.13 162 1613 0.6982 1.03 0.871,1.23 135 1332
733.4 Aseptic necrosis of bone musculoskeletal Both 0.04467 0.9 0.812,0.997 405 4042 0.03236 0.876 0.775,0.989 296 3311
733.6 Costochondritis musculoskeletal Both 0.9162 0.993 0.878,1.12 275 2742 0.857 0.988 0.864,1.13 231 2344
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.7096 0.985 0.911,1.07 701 7003 0.877 0.994 0.915,1.08 622 5905
733.9 Chondromalacia musculoskeletal Both 0.5546 1.07 0.857,1.33 80 800 0.6714 1.05 0.838,1.32 75 729
735 Acquired foot deformities musculoskeletal Both 0.1901 0.972 0.932,1.01 2431 23304 0.1462 0.949 0.884,1.02 853 8390
735.1 Flat foot musculoskeletal Both 0.7674 0.985 0.894,1.09 437 4355 0.7129 1.02 0.916,1.14 345 3499
735.2 Acquired toe deformities musculoskeletal Both 0.955 0.998 0.931,1.07 869 8616 0.2818 0.926 0.806,1.06 223 2380
735.21 Hammer toe (acquired) musculoskeletal Both 0.7112 1.02 0.93,1.11 509 5041 0.3565 1.05 0.947,1.16 373 3873
735.23 Hallux rigidus musculoskeletal Both 0.4246 0.952 0.843,1.07 299 2975 0.2818 0.926 0.806,1.06 223 2380
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.2427 0.962 0.903,1.03 1039 10308 0.1462 0.949 0.884,1.02 853 8390
736 Other acquired deformities of limbs musculoskeletal Both 0.3926 0.98 0.936,1.03 1997 19771 0.4188 1.06 0.923,1.21 210 2078
736.1 Acquired deformities of forearm musculoskeletal Both 0.139 0.851 0.687,1.05 90 892 0.08913 0.814 0.642,1.03 75 721
736.2 Acquired deformities of finger musculoskeletal Both 0.1 0.875 0.747,1.03 169 1684 0.1656 0.882 0.739,1.05 132 1399
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.8974 0.991 0.869,1.13 239 2382 0.1738 0.901 0.776,1.05 193 1885
736.5 Acquired deformities of knee musculoskeletal Both 0.2495 1.09 0.941,1.26 184 1834 0.8091 1.02 0.863,1.21 148 1472
736.6 Unequal leg length (acquired) musculoskeletal Both 0.7328 1.02 0.9,1.16 256 2555 0.4188 1.06 0.923,1.21 210 2078
737 Curvature of spine musculoskeletal Both 0.9616 0.999 0.943,1.06 1268 12573 0.6887 0.985 0.917,1.06 828 7913
737.1 Kyphosis (acquired) musculoskeletal Both 0.7834 1.01 0.914,1.13 383 3819 0.9727 0.998 0.891,1.12 325 3000
737.2 Lordosis (acquired) musculoskeletal Both 0.4446 1.1 0.856,1.42 65 650 0.6281 1.07 0.815,1.4 58 522
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.3963 0.972 0.91,1.04 987 9782 0.6887 0.985 0.917,1.06 828 7913
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.9661 0.999 0.954,1.05 1968 19555 0.03162 0.918 0.849,0.993 721 6667
738.4 Acquired spondylolisthesis musculoskeletal Both 0.01175 0.913 0.85,0.98 863 8617 0.03162 0.918 0.849,0.993 721 6667
739 Contracture of joint musculoskeletal Both 0.1972 0.942 0.861,1.03 522 5203 0.4074 0.96 0.871,1.06 445 4265
740 Osteoarthrosis musculoskeletal Both 0.2618 0.987 0.966,1.01 13133 25195 0.7362 1.0 0.979,1.03 9826 20877
740.1 Osteoarthritis; localized musculoskeletal Both 0.4111 0.987 0.958,1.02 5329 22764 0.7311 0.983 0.89,1.09 437 4123
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.2618 0.981 0.95,1.01 4543 21500 0.9099 1.0 0.966,1.04 3574 17426
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.6266 0.978 0.892,1.07 514 5125 0.7311 0.983 0.89,1.09 437 4123
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.6839 0.988 0.931,1.05 1266 9917 0.9036 1.0 0.938,1.08 928 7502
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.787 1.02 0.903,1.14 303 2974 0.3828 1.06 0.93,1.21 241 2234
740.9 Osteoarthrosis NOS musculoskeletal Both 0.3388 0.989 0.967,1.01 12648 25075 0.7362 1.0 0.979,1.03 9826 20877
741 Symptoms and disorders of the joints musculoskeletal Both 0.7499 0.996 0.97,1.02 6764 29838 0.6998 1.06 0.801,1.39 54 527
741.1 Ankylosis of joint musculoskeletal Both 0.7447 0.977 0.849,1.12 209 2088 0.9016 1.01 0.87,1.17 182 1772
741.2 Stiffness of joint musculoskeletal Both 0.9354 0.997 0.935,1.06 995 9908 0.1459 0.946 0.877,1.02 761 8113
741.3 Difficulty in walking musculoskeletal Both 0.9268 1.0 0.955,1.05 1854 17778 0.857 0.995 0.941,1.05 1405 13681
741.4 Joint effusions musculoskeletal Both 0.5346 0.985 0.94,1.03 1930 19185 0.1315 0.96 0.911,1.01 1557 15663
741.5 Hemarthrosis musculoskeletal Both 0.9594 1.01 0.781,1.3 64 640 0.6998 1.06 0.801,1.39 54 527
741.6 Villonodular synovitis musculoskeletal Both 0.8395 1.03 0.777,1.36 53 522 ,
742 Derangement of joint, non-traumatic musculoskeletal Both 0.3199 0.982 0.948,1.02 3462 27650 0.6823 0.992 0.953,1.03 2712 22209
742.1 Loose body in joint musculoskeletal Both 0.2193 0.889 0.736,1.07 131 1295 0.3162 0.904 0.742,1.1 115 1130
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.4808 0.952 0.83,1.09 243 2414 0.4775 0.95 0.824,1.1 223 2161
742.8 Articular cartilage disorder musculoskeletal Both 0.5534 0.955 0.82,1.11 191 1896 0.8492 0.985 0.842,1.15 175 1646
742.9 Other derangement of joint musculoskeletal Both 0.5 0.987 0.952,1.02 3212 26883 0.6823 0.992 0.953,1.03 2712 22209
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.271 0.985 0.96,1.01 7571 30458 0.2275 0.98 0.948,1.01 4392 24225
743.1 Osteoporosis musculoskeletal Both 0.1109 0.968 0.929,1.01 2982 15823 0.1253 0.881 0.749,1.04 166 1832
743.11 Osteoporosis NOS musculoskeletal Both 0.157 0.971 0.932,1.01 2931 15630 0.2612 0.973 0.929,1.02 2170 12323
743.12 Senile osteoporosis musculoskeletal Both 0.5875 0.974 0.886,1.07 481 4333 0.631 0.972 0.866,1.09 324 3290
743.13 Other specified osteoporosis musculoskeletal Both 0.2891 0.929 0.811,1.06 231 2290 0.1253 0.881 0.749,1.04 166 1832
743.2 Pathologic fracture musculoskeletal Both 0.06918 0.937 0.873,1.01 872 8504 0.8241 0.977 0.795,1.2 92 912
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.182 0.931 0.839,1.03 385 3799 0.6982 0.977 0.868,1.1 296 2882
743.22 Pathologic fracture of femur musculoskeletal Both 0.7015 0.965 0.804,1.16 116 1143 0.8241 0.977 0.795,1.2 92 912
743.4 Stress fracture musculoskeletal Both 0.2723 0.935 0.829,1.05 291 2882 0.8128 0.984 0.863,1.12 236 2415
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.1888 0.981 0.953,1.01 5795 29464 0.2275 0.98 0.948,1.01 4392 24225
745 Pain in joint musculoskeletal Both 0.0537 0.98 0.96,1.0 15755 22596 0.3524 0.989 0.967,1.01 13092 18162
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.3882 1.02 0.973,1.07 1811 18049 0.7096 0.978 0.871,1.1 322 3314
747.1 Cardiac congenital anomalies congenital anomalies Both 0.2109 1.03 0.981,1.09 1446 14417 0.2355 1.08 0.953,1.21 265 2634
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.7709 1.01 0.927,1.11 519 5181 0.975 1.0 0.908,1.1 431 4224
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.6339 1.02 0.941,1.11 632 6299 0.7161 1.02 0.928,1.11 501 4763
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.175 1.08 0.968,1.2 342 3387 0.2355 1.08 0.953,1.21 265 2634
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.9354 1.0 0.906,1.11 402 4014 0.7096 0.978 0.871,1.1 322 3314
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.2307 1.14 0.922,1.4 93 930 0.01905 1.31 1.04,1.63 77 747
749 Congenital anomalies of face and neck congenital anomalies Both 0.8433 0.99 0.899,1.09 455 4540 0.04898 1.24 1.0,1.53 83 801
749.1 Cleft palate congenital anomalies Both 0.2864 0.877 0.689,1.12 81 791 0.1663 0.835 0.647,1.08 72 707
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.04365 1.24 1.01,1.52 90 897 0.04898 1.24 1.0,1.53 83 801
750 Digestive congenital anomalies congenital anomalies Both 0.8299 0.992 0.92,1.07 739 7382 0.7998 0.978 0.823,1.16 145 1516
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.7079 0.978 0.87,1.1 307 3069 0.07943 1.2 0.979,1.47 89 925
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.2917 1.11 0.911,1.36 96 944 0.06457 1.24 0.988,1.55 73 750
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.6194 0.943 0.747,1.19 77 767 0.4645 0.906 0.696,1.18 62 656
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.3148 1.1 0.917,1.31 121 1210 0.07943 1.2 0.979,1.47 89 925
750.15 Congenital anomalies of stomach congenital anomalies Both 0.007413 0.687 0.521,0.904 57 567 ,
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.9397 1.0 0.91,1.11 438 4363 0.7998 0.978 0.823,1.16 145 1516
750.21 Congenital anomalies of intestine congenital anomalies Both 0.9376 1.01 0.885,1.14 262 2613 0.4395 0.947 0.824,1.09 215 2168
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.8472 0.985 0.843,1.15 180 1790 0.7998 0.978 0.823,1.16 145 1516
751 Genitourinary congenital anomalies congenital anomalies Both 0.3698 0.977 0.929,1.03 1682 16764 0.6095 1.05 0.881,1.24 142 1332
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.1343 0.93 0.846,1.02 491 4897 0.1205 0.853 0.698,1.04 118 1089
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.4613 0.958 0.855,1.07 328 3280 0.6714 0.975 0.867,1.1 304 2878
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.01995 0.794 0.653,0.964 132 1301 0.1205 0.853 0.698,1.04 118 1089
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.5164 0.98 0.922,1.04 1139 11355 0.1081 0.89 0.773,1.03 215 2038
751.21 Cystic kidney disease congenital anomalies Both 0.7674 1.01 0.941,1.09 799 7929 0.6237 1.02 0.94,1.11 604 6145
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.09772 0.895 0.785,1.02 251 2506 0.1081 0.89 0.773,1.03 215 2038
751.3 Obstructive genitourinary defect congenital anomalies Both 0.4436 1.07 0.905,1.25 157 1560 0.6095 1.05 0.881,1.24 142 1332
752 Nervous system congenital anomalies congenital anomalies Both 0.05129 0.933 0.871,1.0 908 9073 0.8128 0.981 0.837,1.15 168 1721
752.1 Neural tube defects congenital anomalies Both 0.02239 0.913 0.845,0.987 728 7277 0.7244 0.968 0.806,1.16 127 1283
752.11 Spina bifida congenital anomalies Both 0.3776 0.924 0.776,1.1 144 1440 0.7244 0.968 0.806,1.16 127 1283
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.857 1.01 0.877,1.17 201 2010 0.8128 0.981 0.837,1.15 168 1721
753 Congenital anomalies of the eye congenital anomalies Both 0.7328 1.03 0.872,1.21 146 1451 0.7379 1.03 0.856,1.25 112 1171
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.09772 0.946 0.886,1.01 1006 10049 0.1035 0.915 0.822,1.02 395 3603
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.8933 1.01 0.839,1.22 116 1155 0.9705 0.996 0.809,1.23 96 942
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.0631 0.912 0.827,1.01 470 4675 0.1035 0.915 0.822,1.02 395 3603
755 Congenital anomalies of limbs congenital anomalies Both 0.3508 0.961 0.885,1.04 625 6237 0.6653 0.963 0.813,1.14 142 1359
755.1 Congenital deformities of feet congenital anomalies Both 0.6237 0.971 0.865,1.09 315 3138 0.9572 1.0 0.888,1.13 278 2639
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.228 0.845 0.643,1.11 58 567 ,
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.7194 0.977 0.861,1.11 258 2580 0.6653 0.963 0.813,1.14 142 1359
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.4436 0.938 0.795,1.11 152 1520 0.6653 0.963 0.813,1.14 142 1359
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.4446 1.03 0.961,1.09 1021 10203 0.2547 1.05 0.966,1.14 597 6054
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.8185 1.03 0.79,1.35 55 527 ,
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.01349 1.41 1.07,1.85 56 524 ,
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.5728 0.963 0.844,1.1 246 2459 0.2877 0.924 0.798,1.07 209 2027
756.5 Congenital osteodystrophies congenital anomalies Both 0.1858 1.05 0.976,1.13 743 7419 0.2547 1.05 0.966,1.14 597 6054
757 Congenital anomalies of the integument congenital anomalies Both 0.6622 1.03 0.909,1.16 283 2820 0.6855 1.04 0.866,1.25 126 2274
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.02754 0.809 0.67,0.977 134 1334 0.0257 0.761 0.598,0.968 82 796
758.1 Chromosomal anomalies congenital anomalies Both 0.0263 0.771 0.613,0.97 91 910 0.0257 0.761 0.598,0.968 82 796
759 Other and unspecified congenital anomalies congenital anomalies Both 0.5458 0.972 0.884,1.07 498 4964 0.4943 0.965 0.871,1.07 415 4296
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.5093 0.911 0.691,1.2 57 567 ,
760 Back pain symptoms Both 0.1734 0.985 0.964,1.01 12687 25663 0.4831 0.992 0.968,1.02 10360 20893
761 Cervicalgia symptoms Both 0.03236 0.968 0.94,0.997 5134 32829 0.05754 0.969 0.937,1.0 4166 26711
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.6053 1.01 0.972,1.05 2927 27356 0.5433 1.01 0.971,1.06 2370 21803
764 Sciatica symptoms Both 0.8872 1.0 0.964,1.04 2623 25291 0.6223 0.989 0.945,1.03 2078 20088
765 Cervical radiculitis symptoms Both 0.7691 1.01 0.955,1.06 1401 13966 0.5546 1.02 0.959,1.08 1167 11259
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.6209 1.01 0.976,1.04 4004 31031 0.4355 1.01 0.978,1.05 3283 25135
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.8375 1.02 0.826,1.27 85 835 0.6383 1.06 0.842,1.33 71 671
769 Nonallopathic lesions NEC symptoms Both 0.4989 0.977 0.913,1.05 923 9183 0.875 0.994 0.922,1.07 736 7448
770 Myalgia and myositis unspecified symptoms Both 0.4285 0.987 0.956,1.02 4324 27592 0.3767 0.984 0.95,1.02 3552 22569
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.7112 0.994 0.96,1.03 3638 29710 0.04898 0.918 0.844,1.0 600 6210
771.1 Swelling of limb symptoms Both 0.5546 0.991 0.96,1.02 4511 29862 0.08913 0.969 0.935,1.0 3447 24490
771.2 Cramp of limb symptoms Both 0.1626 0.949 0.881,1.02 791 7856 0.04898 0.918 0.844,1.0 600 6210
772 Symptoms of the muscles symptoms Both 0.4406 0.98 0.93,1.03 1549 15345 0.6699 0.974 0.861,1.1 282 2887
772.1 Muscular wasting and disuse atrophy symptoms Both 0.4121 1.05 0.936,1.18 320 3187 0.2128 1.08 0.955,1.23 270 2664
772.2 Spasm of muscle symptoms Both 0.7586 1.01 0.96,1.06 1780 17782 0.826 1.01 0.954,1.06 1475 14832
772.3 Muscle weakness symptoms Both 0.4217 0.983 0.942,1.03 2339 22770 0.7311 0.992 0.945,1.04 1828 17947
772.4 Rhabdomyolysis symptoms Both 0.7798 0.973 0.806,1.18 117 1170 0.4508 0.922 0.747,1.14 98 935
772.6 Facial weakness symptoms Both 0.6353 0.975 0.876,1.08 377 3746 0.6699 0.974 0.861,1.1 282 2887
773 Pain in limb symptoms Both 0.0389 0.977 0.956,0.999 11393 26958 0.0912 0.979 0.956,1.0 9334 21919
780 Hypothermia/Chills symptoms Both 0.6194 1.03 0.917,1.16 307 3069 0.5957 0.964 0.84,1.11 225 2461
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.7178 0.991 0.944,1.04 1767 17206 0.3459 0.884 0.684,1.14 63 622
781.1 Loss of height symptoms Both 0.06761 0.814 0.653,1.02 91 890 0.3459 0.884 0.684,1.14 63 622
782.3 Edema symptoms Both 0.9863 1.0 0.97,1.03 4591 30849 0.6471 0.992 0.957,1.03 3480 25028
782.6 Pallor and flushing symptoms Both 0.6442 1.02 0.942,1.1 679 6769 0.695 0.983 0.901,1.07 554 5715
783 Fever of unknown origin symptoms Both 0.5649 1.01 0.978,1.04 4616 33703 0.05623 0.866 0.747,1.0 202 2016
783.1 Postprocedural fever symptoms Both 0.0309 0.863 0.754,0.987 248 2473 0.05623 0.866 0.747,1.0 202 2016
785 Abdominal pain symptoms Both 0.4634 0.992 0.971,1.01 13257 25098 0.9376 0.999 0.976,1.02 10999 20258
788 Syncope and collapse symptoms Both 0.09772 0.969 0.933,1.01 3017 29114 0.06918 0.961 0.921,1.0 2378 23349
789 Nausea and vomiting symptoms Both 0.7621 1.0 0.98,1.03 8497 29838 0.8035 1.01 0.926,1.1 543 5238
789.1 Persistent vomiting symptoms Both 0.8872 0.994 0.916,1.08 634 6330 0.8035 1.01 0.926,1.1 543 5238
790 Nonspecific findings on examination of blood symptoms Both 0.05248 0.952 0.906,1.0 1740 17356 0.8279 1.02 0.832,1.26 97 968
790.1 Elevated sedimentation rate symptoms Both 0.3508 1.08 0.922,1.26 158 1580 0.2685 1.1 0.928,1.31 128 1274
790.6 Other abnormal blood chemistry symptoms Both 0.8375 1.0 0.973,1.03 4849 31554 0.9506 1.0 0.967,1.04 3694 25789
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.6012 0.963 0.837,1.11 204 2026 0.2624 0.916 0.785,1.07 175 1662
790.9 Abnormal arterial blood gases symptoms Both 0.9572 0.995 0.826,1.2 123 1230 0.8279 1.02 0.832,1.26 97 968
791 Gangrene symptoms Both 0.6012 1.04 0.902,1.2 212 2104 0.2661 1.1 0.932,1.29 155 1660
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.1941 1.03 0.985,1.08 2171 11972 0.5821 1.02 0.947,1.1 726 6896
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.3715 1.03 0.962,1.11 841 7806 0.5821 1.02 0.947,1.1 726 6896
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.1127 0.932 0.855,1.02 588 5848 0.06457 1.06 0.997,1.12 1207 12942
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.03467 1.05 1.0,1.11 1661 16601 0.06457 1.06 0.997,1.12 1207 12942
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.006166 1.14 1.04,1.26 433 4330 0.798 0.982 0.857,1.13 220 3423
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.1683 1.04 0.985,1.09 1632 15619 0.03548 1.2 1.01,1.43 126 1334
795.8 Abnormal tumor markers symptoms Both 0.2506 0.971 0.923,1.02 1698 13664 0.03548 1.2 1.01,1.43 126 1334
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.01514 1.21 1.04,1.41 167 1662 0.03548 1.2 1.01,1.43 126 1334
796 Elevated prostate specific antigen [PSA] symptoms Male 0.007943 0.929 0.881,0.981 1700 8294 0.004571 0.911 0.854,0.972 1235 6218
797 Shock symptoms Both 0.2371 1.06 0.963,1.17 445 4446 6.761E-4 1.32 1.12,1.54 150 1422
797.1 Cardiogenic shock symptoms Both 0.002951 1.25 1.08,1.44 183 1822 6.761E-4 1.32 1.12,1.54 150 1422
798 Malaise and fatigue symptoms Both 0.9727 1.0 0.976,1.02 8867 29476 0.7816 0.991 0.931,1.06 1052 10944
798.1 Chronic fatigue syndrome symptoms Both 0.7925 1.01 0.953,1.07 1349 13380 0.7816 0.991 0.931,1.06 1052 10944
799 Debility unspecified symptoms Both 0.05888 1.05 0.998,1.1 1672 16007 0.01778 1.07 1.01,1.14 1216 12176
800 Fracture of lower limb injuries & poisonings Both 0.6516 0.989 0.943,1.04 1879 18684 0.7228 0.976 0.854,1.12 238 2387
800.1 Fracture of neck of femur injuries & poisonings Both 0.235 0.941 0.85,1.04 409 4028 0.3724 0.948 0.843,1.07 304 3064
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.7586 0.986 0.903,1.08 539 5364 0.869 1.01 0.913,1.11 418 4182
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.7816 0.989 0.918,1.07 744 7420 0.9506 0.997 0.919,1.08 625 6172
800.4 Fracture of patella injuries & poisonings Both 0.2559 0.933 0.827,1.05 293 2904 0.7228 0.976 0.854,1.12 238 2387
801 Fracture of ankle and foot injuries & poisonings Both 0.7499 0.992 0.945,1.04 1804 17960 0.811 1.01 0.937,1.09 774 7566
801.1 Fracture of foot injuries & poisonings Both 0.9333 0.997 0.931,1.07 913 9098 0.811 1.01 0.937,1.09 774 7566
802 Fracture of pelvis injuries & poisonings Both 0.5861 0.969 0.865,1.09 321 3192 0.514 0.958 0.844,1.09 261 2580
803 Fracture of upper limb injuries & poisonings Both 0.7586 0.992 0.943,1.04 1644 16288 0.3631 1.05 0.941,1.18 337 3490
803.1 Fracture of humerus injuries & poisonings Both 0.09333 0.929 0.853,1.01 592 5913 0.4613 0.966 0.88,1.06 487 4828
803.2 Fracture of radius and ulna injuries & poisonings Both 0.7925 1.01 0.942,1.08 899 8929 0.8472 0.986 0.855,1.14 200 2003
803.21 Colles' fracture injuries & poisonings Both 0.6683 0.972 0.855,1.11 248 2475 0.8472 0.986 0.855,1.14 200 2003
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.7691 1.02 0.917,1.12 419 4190 0.3631 1.05 0.941,1.18 337 3490
804 Fracture of hand or wrist injuries & poisonings Both 0.5129 0.981 0.925,1.04 1272 12504 0.798 1.01 0.947,1.07 1084 10471
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.1687 0.957 0.898,1.02 1082 10755 0.6295 0.983 0.916,1.05 849 8380
807 Fracture of ribs injuries & poisonings Both 0.2951 0.953 0.872,1.04 543 5428 0.2153 0.937 0.846,1.04 417 4234
809 Fracture of unspecified bones injuries & poisonings Both 0.1578 0.97 0.93,1.01 2426 23282 0.3062 0.976 0.932,1.02 2047 19059
817 Concussion injuries & poisonings Both 0.1102 0.94 0.872,1.01 771 7696 0.1629 0.944 0.871,1.02 671 6576
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.3327 1.07 0.937,1.21 240 2380 0.1648 1.17 0.937,1.47 71 682
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.7925 1.03 0.815,1.31 74 740 0.7096 1.05 0.805,1.38 56 561
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.3311 1.11 0.899,1.37 84 837 0.1648 1.17 0.937,1.47 71 682
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.861 0.996 0.948,1.05 1782 17605 0.798 1.01 0.955,1.06 1513 14774
830 Dislocation injuries & poisonings Both 0.6871 1.01 0.971,1.05 3129 28682 0.6138 1.01 0.97,1.05 2657 23623
835 Internal derangement of knee injuries & poisonings Both 0.4753 0.982 0.935,1.03 1774 17453 0.5861 0.985 0.934,1.04 1514 14564
836 Traumatic arthropathy injuries & poisonings Both 0.2698 1.06 0.958,1.17 423 4213 0.1343 1.08 0.975,1.21 356 3373
840 Sprains and strains injuries & poisonings Both 0.1633 0.98 0.954,1.01 6106 31582 0.7063 1.01 0.963,1.06 2008 16594
840.1 Muscle/tendon sprain injuries & poisonings Both 0.3873 0.957 0.867,1.06 429 4269 0.9977 1.0 0.893,1.12 326 3243
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.04898 0.945 0.893,1.0 1343 13394 0.6516 0.986 0.925,1.05 1057 10370
840.3 Joint/ligament sprain injuries & poisonings Both 0.8147 0.995 0.952,1.04 2261 19530 0.7063 1.01 0.963,1.06 2008 16594
841 Sprains and strains of back and neck injuries & poisonings Both 0.7568 0.991 0.933,1.05 1175 11729 0.7482 0.989 0.927,1.06 984 9776
842 Other sprains and strains injuries & poisonings Both 0.3936 1.03 0.965,1.09 1079 10729 0.5458 1.02 0.954,1.09 887 8913
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.2089 1.03 0.983,1.08 1807 18037 0.859 1.01 0.95,1.06 1319 14258
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.8054 0.991 0.922,1.07 797 7958 0.4634 0.967 0.886,1.06 542 6434
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.4256 0.959 0.866,1.06 398 3977 0.4943 0.962 0.861,1.07 343 3161
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.507 0.982 0.932,1.04 1537 15333 0.5272 0.981 0.925,1.04 1245 11953
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.4487 0.951 0.835,1.08 254 2540 0.869 1.01 0.881,1.16 219 2076
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.6653 1.03 0.907,1.16 262 2617 0.2328 1.09 0.947,1.25 209 1984
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.9484 1.0 0.944,1.06 1196 11925 0.9931 1.0 0.938,1.07 1028 9573
858 Complication of internal orthopedic device injuries & poisonings Both 0.02884 0.948 0.903,0.994 1892 18846 0.3228 0.974 0.926,1.03 1641 15417
859 Complication due to other implant and internal device injuries & poisonings Both 0.7129 0.991 0.945,1.04 1820 18191 0.673 0.989 0.937,1.04 1472 14692
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.05623 1.04 0.999,1.07 3389 30552 0.5333 0.931 0.742,1.17 86 998
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.9311 1.01 0.858,1.18 156 1551 0.4539 0.927 0.759,1.13 105 1266
870.2 Open wound of ear injuries & poisonings Both 0.3357 1.1 0.909,1.32 114 1131 0.861 1.02 0.803,1.3 67 909
870.3 Other open wound of head and face injuries & poisonings Both 0.03802 1.07 1.0,1.14 1064 10560 0.743 1.01 0.935,1.1 623 8549
870.4 Open wound of nose and sinus injuries & poisonings Both 0.7621 1.02 0.88,1.19 168 1667 0.8072 1.03 0.807,1.32 61 1345
870.5 Open wound of lip and mouth injuries & poisonings Both 0.2228 0.92 0.803,1.05 230 2293 0.1271 0.883 0.752,1.04 162 1824
870.6 Open wound of neck injuries & poisonings Both 0.3954 1.07 0.919,1.24 184 1833 0.5984 0.938 0.74,1.19 77 1416
870.8 Open wound of genital organs injuries & poisonings Both 0.6622 0.958 0.79,1.16 117 1170 0.5333 0.931 0.742,1.17 86 998
871 Open wounds of extremities injuries & poisonings Both 0.9795 1.0 0.962,1.04 2705 26585 0.3681 1.08 0.914,1.27 145 1561
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.7621 0.985 0.894,1.09 438 4378 0.7586 1.02 0.914,1.13 356 3664
871.2 Open wound of finger(s) injuries & poisonings Both 0.811 0.991 0.918,1.07 731 7291 0.9268 0.996 0.915,1.08 590 6172
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.8035 0.986 0.881,1.1 331 3277 0.787 0.982 0.861,1.12 237 2756
871.4 Open wound of toe(s) injuries & poisonings Both 0.2891 1.08 0.936,1.25 191 1901 0.3681 1.08 0.914,1.27 145 1561
872 Traumatic amputation injuries & poisonings Both 0.6412 1.02 0.926,1.13 415 4129 0.4667 1.04 0.929,1.17 309 3384
873 Broken tooth injuries & poisonings Both 0.3289 1.08 0.921,1.28 148 1471 0.929 1.01 0.842,1.21 122 1252
874 Complication of amputation stump injuries & poisonings Both 0.9057 1.01 0.845,1.21 122 1220 0.8492 1.02 0.83,1.25 97 985
875 Non-healing surgical wound injuries & poisonings Both 0.1774 1.06 0.972,1.17 495 4950 0.879 1.01 0.903,1.13 338 4045
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.2576 1.05 0.967,1.13 669 6680 0.2449 1.05 0.964,1.15 503 5451
907 Injuries to the nervous system injuries & poisonings Both 0.3873 1.03 0.962,1.1 888 8852 0.2679 1.04 0.968,1.12 749 7277
910 Superficial injury, infected injuries & poisonings Both 0.7031 0.959 0.773,1.19 89 887 0.561 0.93 0.73,1.19 73 732
911 Blister injuries & poisonings Both 0.263 1.09 0.939,1.26 185 1838 0.5395 1.05 0.892,1.24 142 1426
912 Insect bite injuries & poisonings Both 0.3715 0.949 0.845,1.06 321 3207 0.07079 0.884 0.773,1.01 238 2625
913 Toxic effect of venom injuries & poisonings Both 0.6471 0.97 0.85,1.11 247 2461 0.7161 1.03 0.887,1.19 194 2027
915 Superficial injury without mention of infection injuries & poisonings Both 0.9354 0.998 0.957,1.04 2368 23457 0.537 0.985 0.939,1.03 1839 18942
916 Contusion injuries & poisonings Both 0.171 1.03 0.989,1.06 3199 30228 0.2254 1.03 0.985,1.07 2508 24512
930 Allergic reaction to food injuries & poisonings Both 0.3162 0.958 0.88,1.04 597 5953 0.8337 0.99 0.905,1.08 500 5160
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.6855 1.02 0.931,1.11 530 5290 0.9354 1.0 0.91,1.11 435 4549
938 Dermatitis due to solar radiation injuries & poisonings Both 2.138E-9 1.1 1.07,1.14 4197 24407 0.2193 1.03 0.983,1.08 1924 20023
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.002399 1.25 1.08,1.44 164 1640 0.1245 1.15 0.962,1.37 107 1375
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 1.905E-8 1.1 1.06,1.14 4001 24007 0.2193 1.03 0.983,1.08 1924 20023
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.6081 0.955 0.8,1.14 140 1400 0.9506 0.994 0.823,1.2 119 1186
942 Infusion and transfusion reaction injuries & poisonings Both 0.6281 1.03 0.903,1.18 221 2205 0.7534 0.975 0.834,1.14 167 1857
946 Anaphylactic shock NOS injuries & poisonings Both 0.7328 1.02 0.918,1.13 385 3830 0.4305 0.954 0.848,1.07 299 3279
947 Urticaria injuries & poisonings Both 0.9572 0.998 0.931,1.07 889 8845 0.8472 0.992 0.919,1.07 718 7664
949 Allergies, other injuries & poisonings Both 0.1514 1.02 0.992,1.05 5269 26807 0.3899 1.01 0.982,1.05 4184 22749
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.9162 1.01 0.911,1.11 419 4176 0.6324 1.03 0.922,1.14 359 3443
957 Injury to other and unspecified nerves injuries & poisonings Both 0.3319 0.907 0.744,1.1 116 1150 0.8892 1.02 0.82,1.26 95 970
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.4831 1.02 0.961,1.09 1073 10721 0.5623 0.932 0.733,1.18 82 741
958.1 Postoperative shock injuries & poisonings Both 0.6138 1.05 0.877,1.25 133 1325 0.2742 1.11 0.918,1.35 112 1012
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.2371 0.873 0.697,1.09 92 911 0.5623 0.932 0.733,1.18 82 741
960 Poisoning by antibiotics injuries & poisonings Both 0.8551 1.0 0.96,1.05 2108 18753 0.52 0.98 0.922,1.04 1133 11137
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.4592 0.94 0.797,1.11 158 1552 0.2716 0.898 0.74,1.09 116 1272
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.7379 0.991 0.938,1.05 1414 13864 0.52 0.98 0.922,1.04 1133 11137
961 Poisoning by other anti-infectives injuries & poisonings Both 0.8241 0.989 0.899,1.09 470 4694 0.3767 0.967 0.897,1.04 746 7239
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.5212 0.978 0.915,1.05 939 9190 0.3767 0.967 0.897,1.04 746 7239
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.8995 1.01 0.923,1.1 561 5601 0.0955 0.885 0.766,1.02 213 2454
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.5152 1.04 0.927,1.16 308 3069 0.4305 1.05 0.926,1.2 242 2480
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.881 1.01 0.898,1.13 305 3029 0.0955 0.885 0.766,1.02 213 2454
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.1276 1.04 0.99,1.08 2031 19919 0.4266 1.02 0.969,1.08 1461 15698
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.1 1.04 0.993,1.09 1980 19507 0.4266 1.02 0.969,1.08 1461 15698
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.5546 0.974 0.892,1.06 538 5360 0.3508 0.951 0.857,1.06 381 3822
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.4943 0.969 0.885,1.06 509 5070 0.3508 0.951 0.857,1.06 381 3822
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.9908 1.0 0.929,1.08 753 7525 0.5248 0.93 0.743,1.16 84 788
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.9886 1.0 0.945,1.06 1305 12848 0.9863 1.0 0.94,1.07 1062 10360
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.3681 0.908 0.735,1.12 98 967 0.5248 0.93 0.743,1.16 84 788
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.6281 1.06 0.844,1.32 86 850 0.9078 0.985 0.767,1.27 71 693
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.9863 0.999 0.937,1.07 1000 9986 0.3289 0.964 0.894,1.04 751 8121
969 Poisoning by psychotropic agents injuries & poisonings Both 0.4093 1.06 0.925,1.21 234 2331 0.3266 1.07 0.931,1.24 200 1971
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.2466 0.846 0.638,1.12 56 546 ,
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.5508 0.96 0.839,1.1 228 2269 0.06918 0.787 0.608,1.02 65 647
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.1222 1.21 0.951,1.53 66 637 ,
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.2056 0.867 0.696,1.08 86 860 0.06918 0.787 0.608,1.02 65 647
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.7228 0.961 0.77,1.2 90 896 0.7211 1.05 0.818,1.34 70 678
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.8453 0.975 0.759,1.25 69 686 0.6934 1.06 0.805,1.39 57 572
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.9954 1.0 0.768,1.3 60 600 ,
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.5902 0.986 0.936,1.04 1565 14843 0.5012 0.98 0.924,1.04 1233 11859
979 Adverse drug events and drug allergies injuries & poisonings Both 0.1991 1.03 0.985,1.08 2116 20636 0.7447 1.01 0.958,1.06 1621 16570
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.3741 1.1 0.893,1.35 91 904 0.4688 1.09 0.862,1.38 71 713
990 Effects radiation NOS injuries & poisonings Both 0.8913 1.0 0.964,1.04 2707 23906 0.3908 0.979 0.932,1.03 1769 18809
994 Sepsis and SIRS injuries & poisonings Both 0.6855 0.99 0.942,1.04 1724 17160 0.05495 1.11 0.998,1.23 383 3717
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.2421 0.926 0.813,1.05 248 2472 0.1832 0.905 0.782,1.05 194 2011
994.2 Sepsis injuries & poisonings Both 0.9795 0.999 0.95,1.05 1636 16281 0.05495 1.11 0.998,1.23 383 3717
994.21 Septic shock injuries & poisonings Both 0.1062 1.08 0.984,1.18 484 4840 0.05495 1.11 0.998,1.23 383 3717
1000 Burns injuries & poisonings Both 0.3908 0.965 0.888,1.05 638 6350 0.8337 1.01 0.923,1.1 534 5328
1001 Foreign body injury injuries & poisonings Both 0.8995 0.997 0.956,1.04 2372 22762 0.861 0.996 0.949,1.05 1820 17941
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.4345 0.988 0.958,1.02 4830 32603 0.975 0.999 0.965,1.03 3654 26714
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.4046 1.03 0.966,1.09 1136 11344 0.877 1.01 0.941,1.07 967 9460
1005 Other symptoms injuries & poisonings Both 0.1107 0.98 0.956,1.0 7724 30626 0.04169 0.971 0.944,0.999 6131 25122
1006 Crushing injury injuries & poisonings Both 0.5333 1.04 0.914,1.19 245 2437 0.2897 1.08 0.938,1.24 218 2053
1007 Injury to blood vessels injuries & poisonings Both 0.1641 0.93 0.839,1.03 411 4106 0.3622 0.95 0.85,1.06 343 3250
1008 Crushing or internal injury to organs injuries & poisonings Both 0.6622 0.985 0.921,1.05 934 9331 0.631 0.981 0.909,1.06 742 7515
1009 Injury, NOS injuries & poisonings Both 0.3622 1.01 0.988,1.03 9284 29063 0.3483 1.01 0.987,1.04 7593 23656
1010 Other tests injuries & poisonings Both 0.9078 1.0 0.981,1.02 19027 19331 0.6471 0.995 0.973,1.02 15255 16004
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.413 1.01 0.984,1.04 5922 32336 0.4932 1.01 0.98,1.04 4540 26628
1012 Late effect injuries & poisonings Both 0.5929 0.98 0.911,1.05 792 7909 0.4416 0.968 0.89,1.05 611 6329
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.4519 1.02 0.975,1.06 2459 23709 0.3221 1.02 0.977,1.07 1890 18334
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3524 1.07 0.923,1.25 177 1770 0.3656 1.08 0.913,1.28 141 1442
1015 Effects of other external causes injuries & poisonings Both 0.1841 1.02 0.991,1.05 5744 32595 0.6442 1.01 0.976,1.04 4415 26828
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.7656 1.01 0.964,1.05 2208 21537 0.6714 0.989 0.941,1.04 1698 16760
1100 Family history injuries & poisonings Both 0.2254 1.09 0.95,1.24 222 2220 0.2786 1.09 0.936,1.26 179 1867
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LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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