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UKB PRS for Cancer of bronchus; lung(165.1) based on GWAS Catalog (2019-05-03)
GWAS reference: 19836008;24880342;28604730.... GWAS source: GWAS Catalog (2019-05-03) PRS method: P&T
PRSweb LD reference: MGI GWAS phenotype: Lung cancer in ever smokers;Squamous cell lung carcinoma;Lun... PRSweb date: 2020-06-20
GWAS ID: GWAS_Catalog_r2019-05-03_X165.1 GWAS URL: https://www.ebi.ac.uk/gwas Genome build: GRCh37/hg19
PRS tuning parameter: P<=2.51e-08 PRS evaluation in: UKB
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CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.8995 0.999 0.977,1.02 8842 88430 0.5888 1.02 0.953,1.09 990 10058
008.5 Bacterial enteritis infectious diseases Both 0.03802 0.959 0.922,0.998 2718 27172 0.06457 0.925 0.852,1.0 629 6474
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.09772 0.934 0.861,1.01 653 6533 0.06457 0.925 0.852,1.0 629 6474
008.6 Viral Enteritis infectious diseases Both 0.05495 1.07 0.999,1.15 862 8622 0.09333 1.06 0.99,1.14 835 8543
008.7 Intestinal infection due to protozoa infectious diseases Both 0.4295 0.892 0.672,1.18 55 550 0.4102 0.887 0.667,1.18 54 548
010 Tuberculosis infectious diseases Both 0.4613 1.06 0.906,1.24 166 1659 0.1936 1.02 0.991,1.05 5805 59045
038 Septicemia infectious diseases Both 0.01023 1.04 1.01,1.08 4175 41776 0.4111 1.04 0.947,1.14 478 4945
038.1 Gram negative septicemia infectious diseases Both 0.3811 1.03 0.962,1.11 850 8501 0.6095 1.02 0.949,1.09 829 8443
038.2 Gram positive septicemia infectious diseases Both 0.4603 1.04 0.944,1.14 494 4978 0.4111 1.04 0.947,1.14 478 4945
041 Bacterial infection NOS infectious diseases Both 0.8395 0.998 0.98,1.02 12017 120377 0.8185 1.0 0.966,1.05 2646 27138
041.1 Staphylococcus infections infectious diseases Both 0.5598 0.989 0.953,1.03 3128 31348 0.4656 0.986 0.95,1.02 3030 31125
041.2 Streptococcus infection infectious diseases Both 0.5152 1.02 0.967,1.07 1641 16433 0.5346 1.02 0.965,1.07 1595 16321
041.4 E. coli infectious diseases Both 0.5212 1.01 0.974,1.05 2730 27319 0.8185 1.0 0.966,1.05 2646 27138
053 Herpes zoster infectious diseases Both 0.1968 1.07 0.966,1.18 411 4137 0.5188 0.931 0.75,1.16 90 937
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.2985 0.894 0.724,1.1 95 949 0.5188 0.931 0.75,1.16 90 937
054 Herpes simplex infectious diseases Both 0.1079 0.889 0.771,1.03 211 2107 0.0537 0.866 0.748,1.0 202 2093
070 Viral hepatitis infectious diseases Both 0.05888 1.09 0.997,1.18 590 5916 0.4335 1.04 0.942,1.15 422 4248
070.1 Viral hepatitis A infectious diseases Both 0.8872 1.02 0.795,1.3 69 690 0.8433 1.03 0.8,1.31 69 685
070.2 Viral hepatitis B infectious diseases Both 0.1014 1.16 0.971,1.39 132 1330 0.08913 1.17 0.977,1.4 131 1322
070.3 Viral hepatitis C infectious diseases Both 0.125 1.11 0.972,1.26 255 2568 0.08511 1.12 0.984,1.28 250 2555
070.4 Chronic hepatitis infectious diseases Both 0.6109 1.03 0.913,1.17 276 2767 0.7816 1.02 0.898,1.15 267 2746
070.9 Hepatitis NOS infectious diseases Both 0.4055 1.04 0.944,1.15 428 4287 0.4335 1.04 0.942,1.15 422 4248
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.507 0.946 0.802,1.12 147 1467 0.4808 0.935 0.775,1.13 116 1164
071.1 HIV infection, symptomatic infectious diseases Both 0.4121 0.925 0.768,1.11 117 1168 0.4808 0.935 0.775,1.13 116 1164
078 Viral warts & HPV infectious diseases Both 0.4207 1.03 0.963,1.09 1004 10036 0.4831 1.02 0.959,1.09 996 9969
079 Viral infection infectious diseases Both 0.227 1.02 0.985,1.07 2769 27694 0.139 1.21 0.941,1.55 63 636
079.1 Varicella infection infectious diseases Both 0.15 1.2 0.936,1.54 64 640 0.139 1.21 0.941,1.55 63 636
080 Postoperative infection infectious diseases Both 0.5821 0.991 0.961,1.02 4473 44775 0.3614 0.986 0.955,1.02 4359 44421
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.07413 1.04 0.996,1.08 2477 24765 0.0871 1.04 0.995,1.08 2429 24545
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.5358 0.927 0.73,1.18 71 709 0.542 0.928 0.73,1.18 70 705
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.2009 1.08 0.958,1.23 279 2810 0.0955 1.16 0.973,1.39 140 1397
110.1 Dermatophytosis infectious diseases Both 0.2208 1.08 0.954,1.23 273 2750 0.0955 1.16 0.973,1.39 140 1397
110.11 Dermatophytosis of nail infectious diseases Both 0.5546 0.929 0.726,1.19 74 756 0.5675 0.93 0.727,1.19 73 751
110.12 Althete's foot infectious diseases Both 0.07943 1.17 0.981,1.4 141 1410 0.0955 1.16 0.973,1.39 140 1397
112 Candidiasis infectious diseases Both 8.318E-4 1.08 1.03,1.13 2126 21275 0.005495 1.07 1.02,1.12 1984 21077
117 Mycoses infectious diseases Both 0.8337 0.987 0.873,1.12 272 2719 0.7691 1.02 0.87,1.21 152 1634
117.4 Aspergillosis infectious diseases Both 0.5035 1.05 0.902,1.23 165 1650 0.7691 1.02 0.87,1.21 152 1634
130 Spirochetal infection infectious diseases Both 0.01288 1.33 1.06,1.65 80 800 0.00871 1.35 1.08,1.69 79 791
133 Arthropod-borne diseases infectious diseases Both 0.3524 0.89 0.697,1.14 69 689 0.3614 0.892 0.698,1.14 69 682
134 Helminthiases infectious diseases Both 0.9441 1.01 0.839,1.21 127 1267 0.7047 1.04 0.85,1.27 105 1053
134.1 Intestinal helminthiases infectious diseases Both 0.6266 1.05 0.86,1.29 106 1058 0.7047 1.04 0.85,1.27 105 1053
136 Other infectious and parasitic diseases infectious diseases Both 0.857 0.987 0.853,1.14 205 2050 0.7638 0.978 0.844,1.13 199 2037
145 Cancer of mouth neoplasms Both 0.375 1.04 0.957,1.12 642 6415 0.3698 1.1 0.896,1.34 100 1042
145.2 Cancer of tongue neoplasms Both 0.6808 1.02 0.912,1.15 310 3096 0.8395 1.01 0.896,1.14 284 3072
145.3 Cancer of major salivary glands neoplasms Both 0.3311 1.1 0.905,1.34 105 1049 0.3698 1.1 0.896,1.34 100 1042
145.5 Cancer of the mouth floor neoplasms Both 0.05129 1.31 0.998,1.73 54 539 ,
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.4325 1.03 0.953,1.12 635 6342 0.09333 0.853 0.709,1.03 113 2607
149.1 Cancer of oropharynx neoplasms Both 0.7586 0.98 0.859,1.12 252 2517 0.7691 0.979 0.852,1.13 220 2494
149.4 Cancer of larynx neoplasms Both 0.6281 1.03 0.911,1.17 265 2640 0.09333 0.853 0.709,1.03 113 2607
149.9 Cancer of of nasal cavities neoplasms Both 0.7925 0.963 0.73,1.27 57 570 ,
150 Cancer of esophagus neoplasms Both 0.8892 0.995 0.924,1.07 762 7630 0.5082 0.975 0.904,1.05 723 7561
151 Cancer of stomach neoplasms Both 0.5821 0.976 0.894,1.06 569 5696 0.6067 0.977 0.895,1.07 556 5639
153 Colorectal cancer neoplasms Both 0.8204 1.0 0.973,1.03 4580 45799 0.5012 0.985 0.941,1.03 2076 21434
153.2 Colon cancer neoplasms Both 0.4898 1.01 0.976,1.05 3105 31046 0.5902 1.01 0.973,1.05 3000 30733
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.7482 0.993 0.95,1.04 2164 21640 0.5012 0.985 0.941,1.03 2076 21434
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.3083 0.948 0.855,1.05 400 4008 0.07586 0.858 0.725,1.02 155 1561
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.04365 0.842 0.713,0.995 158 1580 0.07586 0.858 0.725,1.02 155 1561
157 Pancreatic cancer neoplasms Both 0.7096 0.985 0.909,1.07 659 6582 0.6918 0.984 0.907,1.07 643 6521
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.415 1.03 0.964,1.09 1063 10635 0.5129 1.02 0.959,1.09 1039 10554
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.3639 1.01 0.985,1.04 5567 55694 0.9528 1.0 0.865,1.17 188 1907
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.1245 1.12 0.968,1.3 190 1900 0.1064 1.13 0.973,1.32 179 1883
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.5781 0.961 0.834,1.11 205 2048 0.4742 0.949 0.821,1.1 196 2033
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.9311 1.01 0.869,1.17 193 1925 0.9528 1.0 0.865,1.17 188 1907
164 Cancer of intrathoracic organs neoplasms Both 0.7261 0.954 0.734,1.24 60 600 ,
165 Cancer within the respiratory system neoplasms Both 6.31E-22 1.21 1.16,1.25 2824 28235 ,
165.1 Cancer of bronchus; lung neoplasms Both 5.012E-20 1.22 1.17,1.28 2230 22307 ,
170 Cancer of bone and connective tissue neoplasms Both 0.8241 0.989 0.897,1.09 437 4364 0.8204 1.01 0.903,1.14 312 3278
170.1 Bone cancer neoplasms Both 0.03715 0.825 0.689,0.989 131 1309 0.01 0.781 0.647,0.942 120 1299
170.2 Cancer of connective tissue neoplasms Both 0.6592 1.03 0.916,1.15 331 3303 0.8204 1.01 0.903,1.14 312 3278
172 Skin cancer neoplasms Both 1.995E-4 1.03 1.02,1.05 13495 134987 0.1718 1.06 0.976,1.14 655 6587
172.1 Melanomas of skin, dx or hx neoplasms Both 0.0871 1.04 0.995,1.08 2681 26792 0.06607 1.04 0.998,1.08 2674 26898
172.11 Melanomas of skin neoplasms Both 0.07586 1.04 0.996,1.08 2713 27112 0.06607 1.04 0.998,1.08 2674 26898
172.2 Other non-epithelial cancer of skin neoplasms Both 4.365E-4 1.04 1.02,1.06 11000 110056 2.455E-4 1.04 1.02,1.06 10880 108977
172.3 Carcinoma in situ of skin neoplasms Both 0.2541 1.05 0.968,1.13 666 6656 0.1718 1.06 0.976,1.14 655 6587
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.4842 0.947 0.812,1.1 181 1818 0.3436 0.928 0.794,1.08 178 1808
174 Breast cancer neoplasms Both 0.1169 0.985 0.968,1.0 12686 126597 0.3681 0.914 0.752,1.11 114 1139
174.1 Breast cancer [female] neoplasms Female 0.0871 0.984 0.966,1.0 12476 124506 0.04898 0.981 0.962,1.0 11567 116846
174.11 Malignant neoplasm of female breast neoplasms Female 0.05888 0.982 0.963,1.0 11757 117502 0.04898 0.981 0.962,1.0 11567 116846
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.3917 0.919 0.756,1.12 115 1148 0.3681 0.914 0.752,1.11 114 1139
175 Acquired absence of breast neoplasms Female 0.798 0.995 0.954,1.04 2400 24010 0.6095 0.989 0.948,1.03 2337 23872
180 Cervical cancer and dysplasia neoplasms Female 0.5129 0.985 0.942,1.03 2174 21747 0.7211 0.992 0.947,1.04 2068 20714
180.1 Cervical cancer neoplasms Female 0.7261 0.978 0.865,1.11 272 2720 0.7638 0.981 0.867,1.11 270 2703
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.7907 0.994 0.949,1.04 2078 20784 0.7211 0.992 0.947,1.04 2068 20714
182 Malignant neoplasm of uterus neoplasms Female 0.1919 1.04 0.981,1.1 1282 12836 0.2032 1.04 0.98,1.1 1268 12764
184 Cancer of other female genital organs neoplasms Female 0.007586 1.08 1.02,1.14 1378 13772 0.6934 0.976 0.867,1.1 300 3034
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.006166 1.1 1.03,1.17 967 9667 0.01023 1.09 1.02,1.17 922 9328
184.11 Malignant neoplasm of ovary neoplasms Female 0.01 1.09 1.02,1.17 939 9387 0.01023 1.09 1.02,1.17 922 9328
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.7328 0.98 0.871,1.1 305 3049 0.6934 0.976 0.867,1.1 300 3034
185 Cancer of prostate neoplasms Male 0.08511 0.977 0.951,1.0 5974 58812 0.06918 0.975 0.95,1.0 5890 58093
187 Cancer of other male genital organs neoplasms Male 0.787 1.01 0.921,1.11 449 4485 0.3388 1.1 0.905,1.33 107 1080
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.6607 1.06 0.826,1.35 70 700 0.4786 1.1 0.852,1.41 67 694
187.2 Malignant neoplasm of testis neoplasms Male 0.984 1.0 0.89,1.13 287 2868 0.9247 1.01 0.893,1.13 282 2848
187.8 Neoplasm of uncertain behavior of male genital organs neoplasms Male 0.369 1.09 0.902,1.32 110 1098 0.3388 1.1 0.905,1.33 107 1080
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 5.012E-5 1.07 1.03,1.1 4160 41604 0.5662 1.05 0.884,1.25 140 1426
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.002455 1.1 1.03,1.17 1073 10723 0.471 1.09 0.856,1.4 63 650
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.004169 1.1 1.03,1.17 1033 10324 0.003802 1.1 1.03,1.18 999 10213
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.3963 1.11 0.871,1.42 66 660 0.471 1.09 0.856,1.4 63 650
189.2 Cancer of bladder neoplasms Both 0.004365 1.06 1.02,1.11 2409 24113 0.01514 1.06 1.01,1.11 2094 21194
189.21 Malignant neoplasm of bladder neoplasms Both 0.02188 1.05 1.01,1.1 2142 21447 0.01514 1.06 1.01,1.11 2094 21194
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.7586 1.03 0.866,1.22 144 1439 0.5662 1.05 0.884,1.25 140 1426
190 Cancer of eye neoplasms Both 0.507 0.949 0.813,1.11 176 1758 0.3319 0.925 0.791,1.08 172 1739
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.8166 1.01 0.933,1.09 689 6879 0.7834 1.01 0.925,1.11 516 5188
191.1 Cancer of brain and nervous system neoplasms Both 0.7534 1.01 0.93,1.11 566 5650 0.7834 1.01 0.925,1.11 516 5188
191.11 Cancer of brain neoplasms Both 0.7962 1.01 0.925,1.11 525 5240 0.7834 1.01 0.925,1.11 516 5188
193 Thyroid cancer neoplasms Both 0.6281 0.973 0.871,1.09 346 3466 0.5546 0.967 0.864,1.08 339 3450
194 Cancer of other endocrine glands neoplasms Both 0.9528 0.994 0.806,1.22 95 949 0.7816 0.97 0.784,1.2 91 947
195 Cancer, suspected or other neoplasms Both 0.1233 1.01 0.997,1.03 16967 165463 0.7261 1.0 0.986,1.02 15398 159089
195.1 Malignant neoplasm, other neoplasms Both 0.1365 1.01 0.996,1.03 16267 159497 0.7261 1.0 0.986,1.02 15398 159089
197 Chemotherapy neoplasms Both 0.04266 1.01 1.0,1.03 21433 213213 0.618 1.0 0.989,1.02 20155 212744
198 Secondary malignant neoplasm neoplasms Both 9.55E-6 1.05 1.03,1.07 9552 95503 0.5212 1.06 0.895,1.25 153 1885
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.08913 1.02 0.996,1.05 5368 53670 0.8453 0.997 0.967,1.03 4677 53554
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.01072 1.06 1.01,1.1 2267 22670 0.2333 1.03 0.981,1.08 1721 22606
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.03981 1.06 1.0,1.11 1549 15496 0.07762 1.05 0.995,1.11 1438 15452
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.03802 1.04 1.0,1.09 2665 26648 0.1963 1.03 0.985,1.07 2231 26584
198.5 Secondary malignancy of brain/spine neoplasms Both 0.002512 1.11 1.04,1.19 848 8473 0.4365 1.04 0.946,1.14 478 8451
198.6 Secondary malignancy of bone neoplasms Both 7.586E-4 1.08 1.03,1.13 2161 21600 0.1746 1.04 0.985,1.09 1615 21538
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.246 1.09 0.94,1.27 188 1890 0.5212 1.06 0.895,1.25 153 1885
199 Neoplasm of uncertain behavior neoplasms Both 0.2512 1.03 0.977,1.09 1432 14313 0.7211 0.961 0.77,1.2 93 948
199.4 Neurofibromatosis neoplasms Both 0.5875 0.941 0.756,1.17 95 950 0.7211 0.961 0.77,1.2 93 948
200 Myeloproliferative disease neoplasms Both 1.072E-4 1.14 1.07,1.21 991 9911 0.1567 1.08 0.972,1.2 379 3835
200.1 Polycythemia vera neoplasms Both 0.1422 1.08 0.974,1.2 387 3867 0.1567 1.08 0.972,1.2 379 3835
201 Hodgkin's disease neoplasms Both 0.3381 1.06 0.938,1.21 259 2598 0.2582 1.08 0.947,1.22 248 2580
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.04898 1.04 1.0,1.09 2264 22709 0.9419 0.997 0.914,1.09 564 5779
202.2 Non-Hodgkins lymphoma neoplasms Both 0.0138 1.06 1.01,1.11 1802 18073 0.9419 0.997 0.914,1.09 564 5779
202.21 Nodular lymphoma neoplasms Both 0.8913 0.993 0.891,1.11 363 3647 0.7962 0.986 0.884,1.1 354 3620
202.24 Large cell lymphoma neoplasms Both 0.9594 1.0 0.92,1.09 581 5824 0.9419 0.997 0.914,1.09 564 5779
204 Leukemia neoplasms Both 0.005248 1.07 1.02,1.13 1660 16630 0.1208 1.07 0.982,1.17 547 5512
204.1 Lymphoid leukemia neoplasms Both 0.01862 1.11 1.02,1.21 577 5784 0.07244 1.09 0.993,1.19 499 5037
204.11 Lymphoid leukemia, acute neoplasms Both 0.06607 1.29 0.982,1.7 56 560 0.06607 1.3 0.983,1.71 56 552
204.12 Lymphoid leukemia, chronic neoplasms Both 0.07244 1.09 0.992,1.19 507 5084 0.07244 1.09 0.993,1.19 499 5037
204.2 Myeloid leukemia neoplasms Both 0.03981 1.11 1.0,1.22 462 4617 0.1216 1.15 0.964,1.36 141 1424
204.21 Myeloid leukemia, acute neoplasms Both 0.1824 1.08 0.965,1.21 329 3287 0.2415 1.07 0.956,1.2 326 3256
204.22 Myeloid leukemia, chronic neoplasms Both 0.1496 1.13 0.956,1.34 144 1440 0.1216 1.15 0.964,1.36 141 1424
204.4 Multiple myeloma neoplasms Both 0.1028 1.07 0.986,1.17 555 5560 0.1208 1.07 0.982,1.17 547 5512
208 Benign neoplasm of colon neoplasms Both 0.0182 1.02 1.0,1.03 19856 191891 0.02399 1.02 1.0,1.03 19569 190295
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.6457 1.02 0.951,1.08 978 9781 0.6152 1.02 0.952,1.09 959 9707
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.8974 0.998 0.97,1.03 5243 52452 0.8318 0.997 0.969,1.03 5188 52046
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.6295 0.973 0.871,1.09 347 3466 0.7925 0.985 0.879,1.1 327 3437
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.8147 0.986 0.881,1.1 318 3187 0.7621 0.983 0.877,1.1 314 3163
214 Lipoma neoplasms Both 0.4046 0.989 0.964,1.02 6231 62346 0.2541 0.982 0.953,1.01 4554 45554
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.2301 0.982 0.952,1.01 4585 45872 0.2541 0.982 0.953,1.01 4554 45554
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.1585 1.05 0.983,1.11 1107 11061 0.2023 1.04 0.978,1.11 1096 10982
216 Benign neoplasm of skin neoplasms Both 0.0537 1.02 1.0,1.05 7664 76660 0.04074 1.02 1.0,1.05 7605 76122
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.08318 0.929 0.854,1.01 632 6313 0.1219 0.934 0.856,1.02 586 5889
217.1 Nevus, non-neoplastic neoplasms Both 0.1211 0.934 0.856,1.02 595 5943 0.1219 0.934 0.856,1.02 586 5889
218 Benign neoplasm of uterus neoplasms Female 0.0257 1.02 1.0,1.04 10023 100200 0.6223 1.03 0.922,1.15 354 3522
218.1 Uterine leiomyoma neoplasms Female 0.0195 1.02 1.0,1.05 10241 102376 0.01862 1.02 1.0,1.05 10192 101851
218.2 Other benign neoplasm of uterus neoplasms Female 0.6792 1.02 0.918,1.14 355 3548 0.6223 1.03 0.922,1.15 354 3522
220 Benign neoplasm of ovary neoplasms Female 0.5957 1.01 0.962,1.07 1445 14483 0.492 1.02 0.966,1.08 1437 14394
221 Benign neoplasm of other female genital organs neoplasms Female 0.2344 1.09 0.948,1.24 220 2196 0.2673 1.08 0.942,1.24 217 2182
222 Benign neoplasm of male genital organs neoplasms Male 0.1324 0.879 0.744,1.04 160 1600 0.1368 0.88 0.743,1.04 158 1587
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.2904 1.09 0.93,1.27 173 1729 0.3184 1.09 0.924,1.28 166 1715
224 Benign neoplasm of eye neoplasms Both 0.7568 0.973 0.819,1.16 129 1299 0.7278 0.957 0.748,1.22 64 675
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.5408 0.927 0.728,1.18 67 680 0.7278 0.957 0.748,1.22 64 675
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.03715 1.08 1.0,1.16 816 8155 0.1854 1.2 0.917,1.56 58 583
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.04365 1.08 1.0,1.16 775 7756 0.04898 1.08 1.0,1.16 765 7703
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.1849 1.2 0.918,1.56 59 589 0.1854 1.2 0.917,1.56 58 583
226 Benign neoplasm of thyroid glands neoplasms Both 0.4898 0.957 0.845,1.08 266 2664 0.5346 0.961 0.848,1.09 263 2647
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.1117 1.06 0.987,1.13 861 8635 0.5284 1.04 0.924,1.17 306 3095
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.3999 1.07 0.918,1.24 186 1857 0.4111 1.07 0.916,1.24 184 1834
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.2588 1.06 0.957,1.18 371 3709 0.2864 1.06 0.953,1.18 369 3681
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.5395 1.04 0.923,1.17 309 3114 0.5284 1.04 0.924,1.17 306 3095
228 Hemangioma and lymphangioma, any site neoplasms Both 0.302 1.03 0.976,1.08 1596 15966 0.2924 1.03 0.976,1.08 1572 15845
229 Benign neoplasm of unspecified sites neoplasms Both 0.743 1.01 0.966,1.05 2397 23955 0.6887 1.01 0.967,1.05 2380 23792
860 Bone marrow or stem cell transplant neoplasms Both 0.5483 1.08 0.844,1.38 68 680 0.5888 1.07 0.837,1.37 67 678
240 Simple and unspecified goiter endocrine/metabolic Both 0.6012 1.02 0.94,1.11 600 6016 0.6823 1.02 0.935,1.11 593 5990
241 Nontoxic nodular goiter endocrine/metabolic Both 0.4169 0.975 0.916,1.04 1107 11092 0.5821 0.978 0.904,1.06 669 6735
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.1901 0.938 0.851,1.03 471 4706 0.156 0.932 0.846,1.03 464 4669
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.6026 0.979 0.905,1.06 676 6784 0.5821 0.978 0.904,1.06 669 6735
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.001905 1.08 1.03,1.13 1854 18531 0.04898 1.2 1.0,1.43 133 1370
242.1 Graves' disease endocrine/metabolic Both 0.0955 1.09 0.986,1.2 456 4553 0.0955 1.09 0.986,1.2 449 4510
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.5 1.07 0.873,1.32 91 910 0.6039 1.06 0.857,1.3 88 907
242.3 Exophthalmos endocrine/metabolic Both 0.08318 1.17 0.98,1.39 138 1379 0.04898 1.2 1.0,1.43 133 1370
244 Hypothyroidism endocrine/metabolic Both 0.006026 1.02 1.01,1.04 14590 145053 0.007244 1.02 1.01,1.04 13737 137931
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.1791 1.04 0.981,1.11 1108 11079 0.177 1.04 0.981,1.11 1072 11006
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.2472 1.13 0.921,1.37 101 1010 0.182 1.15 0.937,1.4 98 1004
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.006457 1.02 1.01,1.04 13918 138926 0.007244 1.02 1.01,1.04 13737 137931
245 Thyroiditis endocrine/metabolic Both 0.6855 0.975 0.862,1.1 288 2877 0.9078 1.01 0.874,1.16 207 2091
245.2 Chronic thyroiditis endocrine/metabolic Both 0.798 1.02 0.884,1.17 218 2177 0.9078 1.01 0.874,1.16 207 2091
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.8872 1.01 0.876,1.17 210 2097 0.9078 1.01 0.874,1.16 207 2091
246 Other disorders of thyroid endocrine/metabolic Both 0.2023 0.934 0.842,1.04 397 3975 0.2203 0.936 0.843,1.04 390 3951
250 Diabetes mellitus endocrine/metabolic Both 0.001349 1.02 1.01,1.04 19787 186006 0.03548 1.06 1.0,1.12 1310 13224
250.1 Type 1 diabetes endocrine/metabolic Both 0.002239 1.06 1.02,1.1 2758 27621 0.08913 1.15 0.979,1.34 158 1599
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.001122 1.25 1.09,1.42 239 2389 0.001549 1.24 1.09,1.42 236 2376
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.05248 1.25 0.997,1.56 76 770 0.05754 1.24 0.993,1.55 75 766
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.001514 1.16 1.06,1.27 473 4744 0.001514 1.16 1.06,1.27 471 4708
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.07244 1.15 0.987,1.35 160 1610 0.08913 1.15 0.979,1.34 158 1599
250.2 Type 2 diabetes endocrine/metabolic Both 0.005888 1.02 1.01,1.04 17831 170202 0.7568 1.01 0.924,1.11 495 5016
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.004677 1.33 1.09,1.63 104 1050 0.004074 1.34 1.1,1.64 103 1043
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.173 1.11 0.957,1.28 200 2018 0.1607 1.11 0.959,1.29 197 2003
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.4539 1.03 0.961,1.09 986 9907 0.4898 1.02 0.958,1.09 968 9822
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.7096 1.02 0.928,1.12 503 5066 0.7568 1.01 0.924,1.11 495 5016
250.4 Abnormal glucose endocrine/metabolic Both 0.8995 1.0 0.93,1.09 680 6827 0.9528 0.997 0.902,1.1 403 4137
250.41 Impaired fasting glucose endocrine/metabolic Both 0.929 0.994 0.877,1.13 265 2659 0.9638 0.997 0.879,1.13 262 2634
250.42 Other abnormal glucose endocrine/metabolic Both 0.8414 1.01 0.915,1.11 416 4178 0.9528 0.997 0.902,1.1 403 4137
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.7328 0.97 0.814,1.16 131 1308 0.7943 0.977 0.819,1.17 129 1304
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.4406 0.958 0.858,1.07 349 3495 0.3715 0.951 0.851,1.06 344 3460
250.7 Diabetic retinopathy endocrine/metabolic Both 0.02818 1.06 1.01,1.12 1329 13335 0.03548 1.06 1.0,1.12 1310 13224
251.1 Hypoglycemia endocrine/metabolic Both 0.008128 1.1 1.02,1.17 932 9370 0.00955 1.09 1.02,1.17 909 9300
252 Disorders of parathyroid gland endocrine/metabolic Both 0.05012 1.07 1.0,1.15 873 8719 0.6776 0.965 0.815,1.14 142 1407
252.1 Hyperparathyroidism endocrine/metabolic Both 0.0257 1.09 1.01,1.17 781 7802 0.0166 1.09 1.02,1.18 764 7735
252.2 Hypoparathyroidism endocrine/metabolic Both 0.6871 0.966 0.816,1.14 142 1418 0.6776 0.965 0.815,1.14 142 1407
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.984 1.0 0.924,1.08 681 6821 0.6095 0.954 0.798,1.14 128 1568
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.7447 0.975 0.839,1.13 187 1867 0.3199 0.898 0.726,1.11 93 942
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.4819 0.928 0.753,1.14 95 949 0.3199 0.898 0.726,1.11 93 942
253.2 Pituitary hypofunction endocrine/metabolic Both 0.6067 0.967 0.851,1.1 260 2618 0.6653 0.972 0.855,1.1 258 2597
253.3 Diabetes insipidus endocrine/metabolic Both 0.2649 1.13 0.912,1.4 92 919 0.2239 1.14 0.922,1.42 90 912
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.8974 0.989 0.841,1.16 158 1578 0.6095 0.954 0.798,1.14 128 1568
255 Disorders of adrenal glands endocrine/metabolic Both 0.1233 1.07 0.983,1.16 638 6374 0.01549 1.14 1.03,1.28 353 3578
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.4753 0.945 0.809,1.1 180 1797 0.2673 0.875 0.692,1.11 76 753
255.11 Cushing's syndrome endocrine/metabolic Both 0.9057 1.01 0.827,1.24 103 1029 0.955 1.01 0.817,1.24 96 1026
255.12 Hyperaldosteronism endocrine/metabolic Both 0.2649 0.875 0.691,1.11 76 759 0.2673 0.875 0.692,1.11 76 753
255.2 Adrenal hypofunction endocrine/metabolic Both 0.02344 1.13 1.02,1.26 362 3617 0.01549 1.14 1.03,1.28 353 3578
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.01585 1.14 1.03,1.27 361 3607 0.01549 1.14 1.03,1.28 353 3578
256 Ovarian dysfunction endocrine/metabolic Female 0.811 0.984 0.863,1.12 240 2397 0.5117 0.954 0.829,1.1 209 2085
256.4 Polycystic ovaries endocrine/metabolic Female 0.514 0.954 0.83,1.1 209 2088 0.5117 0.954 0.829,1.1 209 2085
257 Testicular dysfunction endocrine/metabolic Male 0.826 0.981 0.829,1.16 160 1619 0.7499 0.972 0.819,1.16 151 1525
257.1 Testicular hypofunction endocrine/metabolic Male 0.7328 0.971 0.818,1.15 152 1539 0.7499 0.972 0.819,1.16 151 1525
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.9099 1.01 0.828,1.24 102 1020 0.7551 1.03 0.844,1.26 100 1015
259 Other endocrine disorders endocrine/metabolic Both 0.7447 0.972 0.821,1.15 149 1498 0.6166 0.957 0.806,1.14 144 1487
260 Protein-calorie malnutrition endocrine/metabolic Both 0.0182 1.19 1.03,1.37 202 2018 0.879 1.01 0.935,1.08 784 8248
260.1 Cachexia endocrine/metabolic Both 0.3758 0.873 0.646,1.18 51 510 ,
260.6 Anorexia endocrine/metabolic Both 0.865 1.01 0.937,1.08 830 8317 0.879 1.01 0.935,1.08 784 8248
261 Vitamin deficiency endocrine/metabolic Both 0.2178 1.04 0.978,1.1 1199 11974 0.3963 1.1 0.881,1.38 75 763
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.06026 1.08 0.997,1.16 755 7541 0.07943 1.07 0.992,1.16 736 7489
261.4 Vitamin D deficiency endocrine/metabolic Both 0.3828 1.04 0.948,1.15 447 4462 0.3963 1.1 0.881,1.38 75 763
261.41 Rickets or osteomalacia endocrine/metabolic Both 0.2851 1.13 0.905,1.4 77 769 0.3963 1.1 0.881,1.38 75 763
262 Mineral deficiency NEC endocrine/metabolic Both 0.4102 1.06 0.926,1.21 241 2407 0.4198 1.06 0.924,1.21 236 2388
269 Proteinuria endocrine/metabolic Both 0.9661 0.997 0.891,1.12 338 3378 0.9183 0.994 0.887,1.11 331 3343
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.002692 1.2 1.06,1.34 303 3028 0.06761 1.29 0.982,1.69 68 682
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 5.37E-4 1.25 1.1,1.41 261 2608 0.06761 1.29 0.982,1.69 68 682
270.32 Paraproteinemia endocrine/metabolic Both 0.006026 1.23 1.06,1.42 191 1910 0.006457 1.23 1.06,1.43 187 1884
270.33 Amyloidosis endocrine/metabolic Both 0.2924 0.9 0.74,1.09 113 1129 0.3062 0.903 0.742,1.1 112 1119
270.35 Macroglobulinemia endocrine/metabolic Both 0.04365 1.31 1.01,1.71 69 689 0.06761 1.29 0.982,1.69 68 682
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.01175 1.23 1.05,1.45 160 1600 0.007413 1.27 1.07,1.51 137 1380
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.005129 1.28 1.08,1.52 139 1391 0.007413 1.27 1.07,1.51 137 1380
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.9333 1.0 0.988,1.01 34835 235433 0.4365 0.945 0.819,1.09 203 2091
272.1 Hyperlipidemia endocrine/metabolic Both 0.9419 1.0 0.988,1.01 34764 235203 0.06166 1.17 0.992,1.37 160 1617
272.11 Hypercholesterolemia endocrine/metabolic Both 0.879 0.999 0.987,1.01 32324 228083 0.8035 0.998 0.987,1.01 31697 226448
272.12 Hyperglyceridemia endocrine/metabolic Both 0.787 0.962 0.729,1.27 58 580 0.6281 0.933 0.704,1.24 56 576
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.04266 1.18 1.01,1.38 164 1637 0.06166 1.17 0.992,1.37 160 1617
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.5297 0.956 0.831,1.1 211 2109 0.4365 0.945 0.819,1.09 203 2091
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.2 1.02 0.988,1.06 3724 37231 0.6966 1.02 0.933,1.11 554 5531
274.1 Gout endocrine/metabolic Both 0.2388 1.02 0.986,1.06 3171 31705 0.7261 1.04 0.849,1.26 110 1109
274.11 Gouty arthropathy endocrine/metabolic Both 0.5998 1.05 0.866,1.28 112 1119 0.7261 1.04 0.849,1.26 110 1109
274.2 Crystal arthropathies endocrine/metabolic Both 0.7482 1.01 0.934,1.1 613 6124 0.6966 1.02 0.933,1.11 554 5531
274.21 Chondrocalcinosis endocrine/metabolic Both 0.6699 1.02 0.935,1.11 558 5576 0.6966 1.02 0.933,1.11 554 5531
275 Disorders of mineral metabolism endocrine/metabolic Both 0.01259 1.06 1.01,1.11 2107 21070 6.457E-4 1.15 1.06,1.25 647 6470
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.6516 0.976 0.878,1.08 375 3745 0.3573 0.949 0.85,1.06 343 3709
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.2153 1.04 0.979,1.1 1202 12019 0.9226 0.992 0.85,1.16 166 1698
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.8035 0.981 0.842,1.14 171 1717 0.9226 0.992 0.85,1.16 166 1698
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 5.623E-4 1.04 1.02,1.07 7284 72932 0.743 1.03 0.858,1.24 119 1271
276.1 Electrolyte imbalance endocrine/metabolic Both 0.0138 1.04 1.01,1.08 4086 40930 0.3396 0.973 0.921,1.03 1356 14129
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.1476 1.1 0.966,1.26 239 2409 0.2286 1.09 0.949,1.24 229 2379
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.0138 1.06 1.01,1.11 1818 18200 0.04571 1.05 1.0,1.11 1691 18026
276.13 Hyperpotassemia endocrine/metabolic Both 0.005129 1.1 1.03,1.17 969 9728 0.0195 1.08 1.01,1.16 931 9634
276.14 Hypopotassemia endocrine/metabolic Both 0.5023 0.982 0.93,1.04 1424 14235 0.3396 0.973 0.921,1.03 1356 14129
276.4 Acid-base balance disorder endocrine/metabolic Both 0.4645 1.02 0.963,1.09 1161 11629 0.9484 1.01 0.828,1.22 110 1114
276.41 Acidosis endocrine/metabolic Both 0.4677 1.02 0.961,1.09 1056 10577 0.6808 1.01 0.95,1.08 1016 10476
276.42 Alkalosis endocrine/metabolic Both 0.6871 1.04 0.858,1.26 113 1129 0.9484 1.01 0.828,1.22 110 1114
276.5 Hypovolemia endocrine/metabolic Both 0.02344 1.05 1.01,1.09 2827 28265 0.03236 1.04 1.0,1.09 2656 28026
276.6 Fluid overload endocrine/metabolic Both 0.06607 1.1 0.994,1.21 451 4535 0.1112 1.08 0.982,1.2 433 4499
276.8 Polydipsia endocrine/metabolic Both 0.7962 1.02 0.856,1.22 128 1278 0.743 1.03 0.858,1.24 119 1271
277 Other disorders of metabolism endocrine/metabolic Both 0.1064 1.06 0.988,1.13 899 8977 0.9594 1.01 0.762,1.33 52 516
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.5309 1.03 0.93,1.15 362 3613 0.6486 1.03 0.921,1.14 360 3582
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.9226 0.993 0.868,1.14 230 2298 0.9594 1.01 0.762,1.33 52 516
277.51 Lipoprotein disorders endocrine/metabolic Both 0.984 1.0 0.76,1.32 52 520 0.9594 1.01 0.762,1.33 52 516
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.5012 1.01 0.987,1.03 10804 108289 0.4064 1.11 0.865,1.43 66 656
278.1 Obesity endocrine/metabolic Both 0.4932 1.01 0.987,1.03 10642 106670 0.4989 1.01 0.987,1.03 10513 105866
278.3 Localized adiposity endocrine/metabolic Both 0.867 1.02 0.815,1.27 84 838 0.8492 1.02 0.817,1.28 84 832
278.4 Abnormal weight gain endocrine/metabolic Both 0.4055 1.11 0.865,1.43 66 660 0.4064 1.11 0.865,1.43 66 656
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.975 1.0 0.88,1.14 250 2510 0.7834 0.982 0.86,1.12 241 2446
279.1 Immunity deficiency endocrine/metabolic Both 0.8531 0.987 0.854,1.14 209 2100 0.3622 0.921 0.772,1.1 136 1378
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.3141 0.914 0.767,1.09 138 1390 0.3622 0.921 0.772,1.1 136 1378
279.7 Other immunological findings endocrine/metabolic Both 0.9057 0.992 0.871,1.13 248 2478 0.7834 0.982 0.86,1.12 241 2446
275.1 Disorders of iron metabolism hematopoietic Both 5.012E-4 1.15 1.06,1.25 653 6535 6.457E-4 1.15 1.06,1.25 647 6470
280 Iron deficiency anemias hematopoietic Both 0.04898 1.02 1.0,1.05 7610 76168 0.6501 0.978 0.886,1.08 447 4517
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.03162 1.03 1.0,1.05 7311 73153 0.0263 1.03 1.0,1.05 7197 72636
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.6887 0.98 0.889,1.08 452 4541 0.6501 0.978 0.886,1.08 447 4517
281 Other deficiency anemia hematopoietic Both 0.04169 1.07 1.0,1.13 1112 11126 0.7278 0.973 0.834,1.14 179 1823
281.1 Megaloblastic anemia hematopoietic Both 0.05248 1.06 0.999,1.13 1066 10669 0.7278 0.973 0.834,1.14 179 1823
281.11 Pernicious anemia hematopoietic Both 0.0871 1.07 0.991,1.15 750 7514 0.05888 1.08 0.997,1.16 734 7474
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.171 1.11 0.955,1.29 177 1769 0.2168 1.1 0.945,1.28 176 1761
281.13 Folate-deficiency anemia hematopoietic Both 0.8356 0.984 0.845,1.15 183 1836 0.7278 0.973 0.834,1.14 179 1823
281.9 Deficiency anemias hematopoietic Both 0.5047 0.91 0.69,1.2 54 538 ,
282 Hereditary hemolytic anemias hematopoietic Both 0.8995 0.989 0.837,1.17 150 1499 0.4955 0.922 0.732,1.16 85 843
282.8 Other hemoglobinopathies hematopoietic Both 0.871 1.02 0.783,1.34 56 560 0.8531 1.03 0.785,1.34 56 555
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.4581 0.916 0.727,1.15 85 849 0.4955 0.922 0.732,1.16 85 843
283 Acquired hemolytic anemias hematopoietic Both 0.2938 1.1 0.922,1.31 135 1377 0.399 1.09 0.893,1.33 101 1050
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.4446 1.08 0.886,1.32 103 1059 0.399 1.09 0.893,1.33 101 1050
284 Aplastic anemia hematopoietic Both 0.5272 1.03 0.935,1.14 435 4357 0.7691 1.02 0.917,1.12 409 4328
285 Other anemias hematopoietic Both 0.004571 1.03 1.01,1.05 12104 121094 0.1211 1.09 0.978,1.22 361 4117
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.1419 1.1 0.97,1.24 271 2707 0.1462 1.1 0.968,1.24 268 2686
285.2 Anemia of chronic disease hematopoietic Both 0.06918 1.08 0.994,1.16 697 6980 0.1211 1.09 0.978,1.22 361 4117
285.22 Anemia in neoplastic disease hematopoietic Both 0.05248 1.11 0.999,1.22 414 4147 0.1211 1.09 0.978,1.22 361 4117
286 Coagulation defects hematopoietic Both 0.03236 1.08 1.01,1.15 921 9218 0.08128 1.1 0.988,1.22 378 3835
286.1 Congenital coagulation defects hematopoietic Both 0.2104 1.06 0.966,1.17 459 4594 0.6124 0.938 0.731,1.2 62 626
286.11 Von willebrand's disease hematopoietic Both 0.2838 1.12 0.911,1.38 96 959 0.2773 1.12 0.912,1.38 96 953
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.1875 1.08 0.962,1.22 294 2944 0.1811 1.08 0.963,1.22 290 2929
286.13 Congenital factor VIII disorder hematopoietic Both 0.5702 0.931 0.727,1.19 63 630 0.6124 0.938 0.731,1.2 62 626
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.5445 1.07 0.861,1.33 86 860 0.4977 1.08 0.868,1.34 86 852
286.7 Other and unspecified coagulation defects hematopoietic Both 0.06761 1.1 0.993,1.22 386 3867 0.08128 1.1 0.988,1.22 378 3835
287 Purpura and other hemorrhagic conditions hematopoietic Both 2.042E-5 1.12 1.06,1.17 1652 16532 0.9886 1.0 0.778,1.29 68 739
287.1 Spontaneous ecchymoses hematopoietic Both 0.4009 1.08 0.903,1.29 129 1290 0.3899 1.08 0.903,1.3 125 1277
287.2 Allergic purpura hematopoietic Both 0.1151 1.24 0.949,1.62 51 510 ,
287.3 Thrombocytopenia hematopoietic Both 2.399E-4 1.1 1.05,1.16 1553 15543 0.9886 1.0 0.778,1.29 68 739
287.31 Primary thrombocytopenia hematopoietic Both 0.004266 1.16 1.05,1.28 419 4195 0.005888 1.15 1.04,1.27 411 4167
287.32 Secondary thrombocytopenia hematopoietic Both 0.929 1.01 0.793,1.29 75 749 0.9886 1.0 0.778,1.29 68 739
288 Diseases of white blood cells hematopoietic Both 0.04786 1.03 1.0,1.07 3765 37672 0.0123 1.37 1.07,1.76 69 700
288.1 Decreased white blood cell count hematopoietic Both 0.08128 1.03 0.996,1.07 3168 31704 0.3758 1.02 0.98,1.06 2939 31591
288.11 Neutropenia hematopoietic Both 0.1 1.03 0.994,1.07 3176 31784 0.3758 1.02 0.98,1.06 2939 31591
288.3 Eosinophilia hematopoietic Both 0.0123 1.37 1.07,1.75 71 709 0.0123 1.37 1.07,1.76 69 700
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.05248 1.07 0.999,1.15 862 8625 0.3499 1.11 0.893,1.38 84 890
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.2371 1.07 0.954,1.21 290 2897 0.2133 1.08 0.957,1.22 287 2884
289.4 Lymphadenitis hematopoietic Both 0.4217 1.02 0.977,1.06 2602 26061 0.9528 1.0 0.96,1.04 2336 25860
289.5 Diseases of spleen hematopoietic Both 0.4325 1.04 0.947,1.13 516 5153 0.4074 1.04 0.949,1.14 503 5109
289.8 Polycythemia, secondary hematopoietic Both 0.1702 1.09 0.965,1.22 292 2917 0.1633 1.09 0.966,1.23 289 2893
289.9 Abnormality of red blood cells hematopoietic Both 0.3532 1.11 0.895,1.36 90 900 0.3499 1.11 0.893,1.38 84 890
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.4508 1.02 0.972,1.07 1929 19281 0.7656 1.04 0.812,1.33 69 705
290.1 Dementias mental disorders Both 0.6531 0.985 0.924,1.05 1004 10032 0.6324 0.965 0.835,1.12 194 1986
290.11 Alzheimer's disease mental disorders Both 0.9863 1.0 0.908,1.1 431 4307 0.869 0.992 0.899,1.09 421 4263
290.16 Vascular dementia mental disorders Both 0.6194 0.965 0.836,1.11 201 2008 0.6324 0.965 0.835,1.12 194 1986
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.1995 1.05 0.973,1.14 650 6501 0.1832 1.06 0.974,1.15 621 6432
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.8318 1.03 0.804,1.31 70 709 0.7656 1.04 0.812,1.33 69 705
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.1476 0.949 0.883,1.02 836 8385 0.1091 0.921 0.834,1.02 419 4346
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.5834 0.952 0.8,1.13 132 1320 0.3828 0.924 0.774,1.1 129 1314
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.6918 0.976 0.863,1.1 286 2867 0.5636 0.964 0.851,1.09 274 2840
291.8 Alteration of consciousness mental disorders Both 0.1476 0.93 0.843,1.03 436 4376 0.1091 0.921 0.834,1.02 419 4346
292 Neurological disorders mental disorders Both 0.07079 1.03 0.998,1.06 4621 46260 0.6808 1.03 0.908,1.16 286 3047
292.1 Aphasia/speech disturbance mental disorders Both 0.1986 1.04 0.982,1.09 1504 15074 0.1866 1.04 0.983,1.09 1456 14961
292.2 Mild cognitive impairment mental disorders Both 0.8299 1.02 0.877,1.18 190 1907 0.857 1.01 0.873,1.18 182 1894
292.3 Memory loss mental disorders Both 0.867 0.993 0.919,1.07 696 6978 0.9705 1.0 0.926,1.08 684 6924
292.4 Altered mental status mental disorders Both 0.05623 1.04 0.999,1.09 2181 21827 0.1552 1.03 0.988,1.08 2038 21638
292.6 Hallucinations mental disorders Both 0.271 1.07 0.95,1.2 307 3073 0.6808 1.03 0.908,1.16 286 3047
293 Symptoms involving head and neck mental disorders Both 0.4831 1.02 0.971,1.06 2078 20779 0.4457 1.03 0.959,1.1 866 8946
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.2735 1.04 0.971,1.11 901 9010 0.4457 1.03 0.959,1.1 866 8946
295 Schizophrenia and other psychotic disorders mental disorders Both 0.8511 1.01 0.938,1.08 841 8446 0.9484 0.995 0.849,1.17 164 1698
295.1 Schizophrenia mental disorders Both 0.4977 1.03 0.946,1.12 574 5766 0.4395 1.03 0.949,1.13 563 5752
295.2 Paranoid disorders mental disorders Both 0.3648 1.07 0.921,1.25 178 1780 0.3573 1.08 0.921,1.26 175 1773
295.3 Psychosis mental disorders Both 0.9506 0.995 0.851,1.16 169 1710 0.9484 0.995 0.849,1.17 164 1698
296 Mood disorders mental disorders Both 0.873 0.998 0.98,1.02 12372 123822 0.05888 0.901 0.809,1.0 357 3592
296.1 Bipolar mental disorders Both 0.6653 1.01 0.952,1.08 1059 10599 0.7228 1.01 0.95,1.08 1045 10561
296.2 Depression mental disorders Both 0.8472 0.998 0.979,1.02 11737 117469 0.05888 0.901 0.809,1.0 357 3592
296.22 Major depressive disorder mental disorders Both 0.03981 0.893 0.802,0.995 361 3604 0.05888 0.901 0.809,1.0 357 3592
297.2 Suicide or self-inflicted injury mental disorders Both 0.1977 1.08 0.961,1.21 311 3070 0.1758 1.08 0.964,1.22 303 3056
300 Anxiety disorders mental disorders Both 0.7379 0.996 0.971,1.02 6844 68484 0.125 0.864 0.716,1.04 112 1126
300.1 Anxiety disorder mental disorders Both 0.5715 0.993 0.967,1.02 6324 63282 0.1517 1.07 0.976,1.17 494 4983
300.11 Generalized anxiety disorder mental disorders Both 0.1563 0.881 0.74,1.05 149 1499 0.06166 0.845 0.708,1.01 147 1495
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.6266 1.02 0.944,1.1 707 7065 0.8531 1.01 0.932,1.09 687 7036
300.13 Phobia mental disorders Both 0.1327 1.07 0.979,1.17 501 5013 0.1517 1.07 0.976,1.17 494 4983
300.3 Obsessive-compulsive disorders mental disorders Both 0.4645 1.07 0.894,1.28 140 1407 0.4603 1.07 0.894,1.28 140 1403
300.4 Dysthymic disorder mental disorders Both 0.4797 0.907 0.693,1.19 53 530 0.4797 0.907 0.693,1.19 53 530
300.8 Acute reaction to stress mental disorders Both 0.4887 0.937 0.781,1.13 124 1238 0.4256 0.928 0.772,1.12 123 1232
300.9 Posttraumatic stress disorder mental disorders Both 0.1072 0.857 0.711,1.03 113 1129 0.125 0.864 0.716,1.04 112 1126
301 Personality disorders mental disorders Both 0.6546 0.975 0.872,1.09 334 3338 0.06166 0.836 0.693,1.01 117 1184
301.2 Antisocial/borderline personality disorder mental disorders Both 0.07943 0.846 0.702,1.02 119 1186 0.06166 0.836 0.693,1.01 117 1184
302 Sexual and gender identity disorders mental disorders Both 0.5152 1.04 0.924,1.17 283 2845 0.6166 1.03 0.915,1.16 279 2827
303 Psychogenic and somatoform disorders mental disorders Both 0.4842 0.966 0.878,1.06 467 4679 0.09772 0.851 0.703,1.03 121 1224
303.3 Psychogenic disorder mental disorders Both 0.869 1.01 0.904,1.13 350 3510 0.9078 0.994 0.889,1.11 345 3492
303.4 Somatoform disorder mental disorders Both 0.09772 0.852 0.705,1.03 123 1229 0.09772 0.851 0.703,1.03 121 1224
304 Adjustment reaction mental disorders Both 0.3981 1.05 0.935,1.18 293 2936 0.4295 1.05 0.932,1.18 290 2926
305.2 Eating disorder mental disorders Both 0.5623 0.939 0.76,1.16 90 900 0.561 0.939 0.76,1.16 90 898
306 Other mental disorder mental disorders Both 0.01318 1.02 1.0,1.03 28056 230087 0.2432 1.07 0.954,1.2 310 3138
306.9 Tension headache mental disorders Both 0.3041 1.06 0.947,1.19 315 3148 0.2432 1.07 0.954,1.2 310 3138
313 Pervasive developmental disorders mental disorders Both 0.4325 1.1 0.869,1.39 76 770 0.7816 1.04 0.793,1.36 52 536
313.3 Autism mental disorders Both 0.7413 1.05 0.8,1.37 53 539 0.7816 1.04 0.793,1.36 52 536
315 Develomental delays and disorders mental disorders Both 0.9616 1.0 0.902,1.11 351 3517 0.04266 1.25 1.01,1.56 81 873
315.1 Learning disorder mental disorders Both 0.2118 0.903 0.77,1.06 161 1610 0.1871 0.898 0.765,1.05 160 1602
315.2 Speech and language disorder mental disorders Both 0.04074 1.25 1.01,1.54 88 880 0.04266 1.25 1.01,1.56 81 873
316 Substance addiction and disorders mental disorders Both 0.4909 1.01 0.982,1.04 5313 53131 0.3945 0.891 0.685,1.16 58 595
316.1 Polyneuropathy due to drugs mental disorders Both 0.4977 0.914 0.705,1.19 60 599 0.3945 0.891 0.685,1.16 58 595
317 Alcohol-related disorders mental disorders Both 0.1387 1.01 0.996,1.03 12696 126892 0.875 0.994 0.925,1.07 812 8326
317.1 Alcoholism mental disorders Both 0.2128 1.01 0.992,1.04 8890 88923 0.875 0.994 0.925,1.07 812 8326
317.11 Alcoholic liver damage mental disorders Both 0.9506 1.0 0.933,1.08 838 8392 0.875 0.994 0.925,1.07 812 8326
318 Tobacco use disorder mental disorders Both 0.03467 1.02 1.0,1.03 19359 185465 0.3516 1.01 0.992,1.02 18511 184447
320 Meningitis neurological Both 0.07586 0.916 0.832,1.01 444 4447 0.07079 0.914 0.829,1.01 435 4410
323 Encephalitis neurological Both 0.9099 1.01 0.901,1.12 342 3422 0.6887 0.952 0.75,1.21 74 736
323.2 Acute (transverse) myelitis neurological Both 0.6839 0.952 0.75,1.21 74 739 0.6887 0.952 0.75,1.21 74 736
324 Other CNS infection and poliomyelitis neurological Both 0.2388 0.931 0.828,1.05 292 2916 0.1897 0.923 0.819,1.04 286 2896
327 Sleep disorders neurological Both 0.6501 1.01 0.955,1.08 1164 11659 0.743 1.03 0.867,1.22 134 1377
327.3 Sleep apnea neurological Both 0.5649 1.01 0.978,1.04 4428 44318 0.4529 1.01 0.981,1.04 4374 43947
327.4 Insomnia neurological Both 0.9863 1.0 0.856,1.17 163 1660 0.743 1.03 0.867,1.22 134 1377
327.41 Organic or persistent insomnia neurological Both 0.7047 1.03 0.872,1.23 136 1390 0.743 1.03 0.867,1.22 134 1377
331 Other cerebral degenerations neurological Both 0.1837 1.04 0.981,1.11 1142 11416 0.2655 1.06 0.959,1.17 414 4257
331.1 Hydrocephalus neurological Both 0.6887 1.02 0.93,1.12 502 5014 0.7674 1.01 0.925,1.11 483 4973
331.9 Cerebral degeneration, unspecified neurological Both 0.3311 1.05 0.953,1.15 430 4298 0.2655 1.06 0.959,1.17 414 4257
332 Parkinson's disease neurological Both 0.3412 0.97 0.912,1.03 1126 11254 0.3412 0.97 0.912,1.03 1114 11142
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.561 1.02 0.953,1.09 894 8954 0.6653 1.03 0.902,1.17 253 2511
333.1 Essential tremor neurological Both 0.5861 1.04 0.904,1.2 216 2157 0.6397 1.03 0.897,1.19 206 2134
333.2 Myoclonus neurological Both 0.2667 1.13 0.914,1.39 96 958 0.3266 1.11 0.898,1.38 89 946
333.4 Torsion dystonia neurological Both 0.6637 1.03 0.903,1.17 253 2528 0.6653 1.03 0.902,1.17 253 2511
334 Degenerative disease of the spinal cord neurological Both 0.0389 1.05 1.0,1.1 1812 18130 0.2377 1.08 0.95,1.23 241 2422
334.1 Spinocerebellar disease neurological Both 0.2992 1.1 0.917,1.33 117 1169 0.3304 1.1 0.911,1.32 116 1159
334.2 Anterior horn cell disease neurological Both 0.2388 1.08 0.95,1.23 245 2446 0.2377 1.08 0.95,1.23 241 2422
335 Multiple sclerosis neurological Both 0.003715 1.09 1.03,1.15 1340 13385 0.00631 1.08 1.02,1.14 1325 13343
337 Disorders of the autonomic nervous system neurological Both 0.6109 1.03 0.911,1.17 266 2668 0.9908 0.999 0.78,1.28 68 716
337.1 Peripheral autonomic neuropathy neurological Both 0.6902 1.05 0.827,1.33 72 719 0.9908 0.999 0.78,1.28 68 716
338 Pain neurological Both 0.7568 1.01 0.939,1.09 768 7692 0.3467 1.05 0.946,1.17 373 3794
338.1 Acute pain neurological Both 0.3648 0.953 0.858,1.06 394 3937 0.3733 0.953 0.857,1.06 379 3910
338.2 Chronic pain neurological Both 0.3802 1.05 0.943,1.17 380 3817 0.3467 1.05 0.946,1.17 373 3794
339 Other headache syndromes neurological Both 0.1172 1.02 0.995,1.04 7819 78241 0.1225 1.02 0.995,1.04 7695 77749
340 Migraine neurological Both 0.6792 0.992 0.954,1.03 2860 28602 0.2432 0.918 0.795,1.06 208 2104
340.1 Migrain with aura neurological Both 0.2767 0.924 0.801,1.07 212 2117 0.2432 0.918 0.795,1.06 208 2104
341 Other demyelinating diseases of central nervous system neurological Both 0.3076 1.07 0.939,1.22 252 2535 0.2489 1.08 0.947,1.23 249 2523
342 Hemiplegia neurological Both 0.2366 1.03 0.979,1.09 1494 14947 0.2786 1.03 0.976,1.09 1448 14824
343 Infantile cerebral palsy neurological Both 0.9078 1.01 0.852,1.2 145 1450 0.881 1.01 0.853,1.2 142 1436
344 Other paralytic syndromes neurological Both 0.7691 0.988 0.912,1.07 658 6593 0.8453 0.992 0.914,1.08 636 6555
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.3105 1.02 0.986,1.05 5023 50270 0.7762 1.01 0.963,1.05 2155 22181
345.1 Epilepsy neurological Both 0.8395 1.01 0.939,1.08 866 8661 0.3048 0.936 0.825,1.06 269 2748
345.11 Generalized convulsive epilepsy neurological Both 0.5534 0.971 0.88,1.07 439 4385 0.4853 0.966 0.875,1.07 431 4354
345.12 Partial epilepsy neurological Both 0.3048 0.937 0.827,1.06 277 2776 0.3048 0.936 0.825,1.06 269 2748
345.3 Convulsions neurological Both 0.7534 1.01 0.964,1.05 2235 22339 0.7762 1.01 0.963,1.05 2155 22181
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.6324 1.04 0.88,1.23 144 1438 0.6683 1.04 0.874,1.23 136 1426
348 Other conditions of brain neurological Both 0.7834 1.01 0.938,1.09 778 7808 0.1862 0.931 0.837,1.04 370 3871
348.2 Cerebral edema and compression of brain neurological Both 0.06607 0.887 0.78,1.01 268 2678 0.07762 0.888 0.779,1.01 252 2656
348.4 Cerebral cysts neurological Both 0.01259 1.24 1.05,1.47 133 1350 0.02138 1.22 1.03,1.45 132 1341
348.7 Coma neurological Both 0.9795 1.0 0.899,1.12 358 3596 0.865 0.991 0.888,1.1 352 3565
348.8 Encephalopathy, not elsewhere classified neurological Both 0.826 1.02 0.888,1.16 249 2504 0.8892 0.99 0.865,1.13 246 2480
348.9 Other conditions of brain, NOS neurological Both 0.3467 0.952 0.858,1.06 390 3899 0.1862 0.931 0.837,1.04 370 3871
349 Other and unspecified disorders of the nervous system neurological Both 0.5333 1.04 0.928,1.16 342 3414 0.3963 1.05 0.939,1.17 332 3394
350 Abnormal movement neurological Both 0.9484 1.0 0.962,1.04 2671 26722 0.07413 1.3 0.976,1.72 52 536
350.1 Abnormal involuntary movements neurological Both 0.1016 0.943 0.88,1.01 887 8852 0.1186 0.945 0.881,1.01 867 8783
350.2 Abnormality of gait neurological Both 0.06918 1.05 0.996,1.1 1596 15969 0.1271 1.04 0.988,1.1 1524 15800
350.3 Lack of coordination neurological Both 0.7834 0.985 0.885,1.1 363 3638 0.875 0.991 0.89,1.1 356 3599
350.6 Disturbances of sensation of smell and taste neurological Both 0.05012 1.32 1.0,1.75 54 540 0.07413 1.3 0.976,1.72 52 536
351 Other peripheral nerve disorders neurological Both 0.6966 1.0 0.985,1.02 12420 124321 0.7112 1.0 0.985,1.02 12307 123449
352 Disorders of other cranial nerves neurological Both 0.03715 1.06 1.0,1.12 1370 13706 0.1618 1.05 0.98,1.13 862 8716
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.0955 1.08 0.986,1.19 463 4638 0.07413 1.09 0.992,1.2 458 4607
352.2 Facial nerve disorders [CN7] neurological Both 0.1542 1.05 0.981,1.13 880 8795 0.1618 1.05 0.98,1.13 862 8716
353 Nerve root and plexus disorders neurological Both 0.7998 0.992 0.933,1.05 1131 11319 0.8551 0.976 0.755,1.26 57 566
353.1 Nerve plexus lesions neurological Both 0.5508 0.941 0.772,1.15 114 1138 0.5689 0.944 0.774,1.15 114 1134
353.2 Nerve root lesions neurological Both 0.8831 0.981 0.758,1.27 57 570 0.8551 0.976 0.755,1.26 57 566
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.4477 0.938 0.794,1.11 152 1520 0.4977 0.944 0.799,1.11 152 1507
357 Inflammatory and toxic neuropathy neurological Both 0.07943 1.05 0.994,1.11 1361 13648 0.1033 1.05 0.99,1.11 1321 13513
358 Myoneural disorders neurological Both 0.6998 0.973 0.847,1.12 211 2109 0.2818 0.923 0.797,1.07 188 1901
358.1 Myasthenia gravis neurological Both 0.3342 0.931 0.806,1.08 192 1919 0.2818 0.923 0.797,1.07 188 1901
359 Muscular dystrophies and other myopathies neurological Both 0.03802 1.1 1.01,1.21 465 4646 0.04677 1.12 1.0,1.25 350 3567
359.1 Muscular dystrophies neurological Both 0.955 0.995 0.831,1.19 122 1219 0.9528 0.995 0.831,1.19 122 1212
359.2 Myopathy neurological Both 0.06918 1.1 0.992,1.23 360 3597 0.04677 1.12 1.0,1.25 350 3567
360 Disorders of the globe sense organs Both 0.7962 0.986 0.882,1.1 337 3367 0.8337 0.986 0.866,1.12 249 2491
360.2 Progressive myopia sense organs Both 0.859 0.988 0.869,1.12 251 2508 0.8337 0.986 0.866,1.12 249 2491
361 Retinal detachments and defects sense organs Both 0.04677 1.04 1.0,1.08 3246 32453 0.3396 1.12 0.888,1.41 67 677
361.1 Retinal detachment with retinal defect sense organs Both 0.1837 1.04 0.982,1.1 1389 13884 0.1854 1.04 0.982,1.1 1379 13768
361.2 Retinoschisis and retinal cysts sense organs Both 0.3516 1.12 0.886,1.4 68 680 0.3396 1.12 0.888,1.41 67 677
362 Other retinal disorders sense organs Both 0.7551 1.01 0.972,1.04 3836 38370 0.1069 1.17 0.966,1.42 115 1151
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.4853 1.02 0.972,1.06 2182 21813 0.5598 1.01 0.97,1.06 2147 21552
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.4864 1.02 0.972,1.06 2179 21783 0.5598 1.01 0.97,1.06 2147 21552
362.3 Other nondiabetic retinopathy sense organs Both 0.9863 0.999 0.852,1.17 161 1609 0.2089 0.875 0.711,1.08 99 983
362.31 Separation of retinal layers sense organs Both 0.2208 0.878 0.713,1.08 99 990 0.2089 0.875 0.711,1.08 99 983
362.4 Retinal vascular changes and abnomalities sense organs Both 0.5623 0.979 0.912,1.05 848 8477 0.5998 0.981 0.913,1.05 834 8385
362.6 Peripheral retinal degenerations sense organs Both 0.3428 1.08 0.925,1.25 182 1827 0.2958 1.08 0.932,1.26 181 1812
362.7 Hereditary retinal dystrophies sense organs Both 0.1862 0.858 0.683,1.08 82 812 0.2477 0.874 0.695,1.1 81 808
362.8 Retinal hemorrhage/ischemia sense organs Both 0.1312 1.16 0.957,1.4 116 1159 0.1069 1.17 0.966,1.42 115 1151
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.2023 1.11 0.948,1.29 170 1699 0.7129 0.954 0.742,1.23 68 685
363.3 Chorioretinal scars sense organs Both 0.9162 0.987 0.77,1.27 69 690 0.7129 0.954 0.742,1.23 68 685
364 Corneal opacity and other disorders of cornea sense organs Both 0.9333 0.997 0.92,1.08 647 6485 0.9506 0.994 0.814,1.21 100 991
364.1 Corneal opacity sense organs Both 0.7586 0.967 0.782,1.2 90 910 0.8147 0.975 0.787,1.21 88 901
364.2 Corneal edema sense organs Both 0.3304 0.893 0.712,1.12 79 800 0.3436 0.896 0.715,1.12 79 795
364.4 Corneal degenerations sense organs Both 0.1528 1.11 0.962,1.28 201 2017 0.6138 1.06 0.843,1.34 85 868
364.41 Keratoconus sense organs Both 0.6501 1.05 0.838,1.33 86 869 0.6138 1.06 0.843,1.34 85 868
364.5 Corneal dystrophy sense organs Both 0.6592 0.969 0.843,1.11 211 2109 0.6808 0.971 0.844,1.12 211 2095
364.9 Cornea replaced by transplant sense organs Both 0.9057 0.988 0.809,1.21 100 1000 0.9506 0.994 0.814,1.21 100 991
365 Glaucoma sense organs Both 0.1406 0.977 0.947,1.01 4408 44136 0.173 0.947 0.876,1.02 693 6919
365.1 Open-angle glaucoma sense organs Both 0.6966 0.987 0.926,1.05 1032 10346 0.5188 0.979 0.918,1.04 1016 10160
365.11 Primary open angle glaucoma sense organs Both 0.5916 0.983 0.922,1.05 1026 10287 0.5188 0.979 0.918,1.04 1016 10160
365.2 Primary angle-closure glaucoma sense organs Both 0.1762 0.948 0.877,1.02 698 6996 0.173 0.947 0.876,1.02 693 6919
366 Cataract sense organs Both 0.9376 1.0 0.986,1.02 19926 168711 0.4955 1.07 0.874,1.32 100 1011
366.1 Nonsenile Cataract sense organs Both 0.05623 0.787 0.616,1.01 69 700 0.06166 0.789 0.616,1.01 68 695
366.2 Senile cataract sense organs Both 0.3062 0.988 0.966,1.01 8231 81909 0.3155 0.988 0.966,1.01 8129 81019
366.3 Traumatic cataract sense organs Both 0.6607 1.05 0.853,1.29 102 1019 0.4955 1.07 0.874,1.32 100 1011
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.271 0.977 0.937,1.02 2408 24092 0.8222 0.991 0.917,1.07 702 7138
367.1 Myopia sense organs Both 0.6516 0.987 0.931,1.05 1251 12519 0.5875 0.984 0.928,1.04 1243 12425
367.2 Astigmatism sense organs Both 0.7674 0.978 0.843,1.13 190 1899 0.7178 0.973 0.838,1.13 187 1891
367.8 Hypermetropia sense organs Both 0.241 0.927 0.816,1.05 253 2530 0.2965 0.934 0.822,1.06 250 2504
367.9 Blindness and low vision sense organs Both 0.863 0.993 0.92,1.07 719 7198 0.8222 0.991 0.917,1.07 702 7138
368 Visual disturbances sense organs Both 0.9247 1.0 0.965,1.04 2962 29648 0.4624 1.03 0.949,1.12 596 6065
368.1 Amblyopia sense organs Both 0.9141 0.995 0.91,1.09 532 5322 0.8356 0.991 0.905,1.08 522 5267
368.2 Diplopia and disorders of binocular vision sense organs Both 0.5902 1.02 0.946,1.1 727 7288 0.7228 1.01 0.938,1.1 714 7236
368.3 Anisometropia sense organs Both 0.4285 0.935 0.793,1.1 154 1548 0.4315 0.935 0.792,1.1 152 1542
368.4 Visual field defects sense organs Both 0.6109 1.03 0.92,1.15 333 3327 0.6668 1.03 0.915,1.15 325 3298
368.9 Subjective visual disturbances sense organs Both 0.317 1.04 0.96,1.13 612 6115 0.4624 1.03 0.949,1.12 596 6065
369 Infection of the eye sense organs Both 0.01259 1.12 1.02,1.22 553 5544 0.06026 1.14 0.994,1.31 203 2107
369.2 Eye infection, viral sense organs Both 0.7328 1.03 0.863,1.23 125 1257 0.8241 0.98 0.817,1.18 122 1244
369.5 Conjunctivitis, infectious sense organs Both 0.0537 1.14 0.998,1.31 213 2128 0.06026 1.14 0.994,1.31 203 2107
370 Keratitis sense organs Both 0.2523 1.07 0.951,1.21 286 2855 0.3908 1.08 0.909,1.28 141 1396
370.1 Corneal ulcer sense organs Both 0.399 1.08 0.908,1.27 141 1408 0.3908 1.08 0.909,1.28 141 1396
371 Inflammation of the eye sense organs Both 0.3724 0.983 0.947,1.02 3045 30480 0.7709 0.994 0.952,1.04 2335 23380
371.1 Uveitis, noninfectious or NOS sense organs Both 0.955 1.0 0.912,1.1 482 4821 0.877 1.01 0.916,1.11 479 4773
371.3 Inflammation of eyelids sense organs Both 0.8035 0.995 0.953,1.04 2353 23555 0.7709 0.994 0.952,1.04 2335 23380
372 Disorders of conjunctiva sense organs Both 0.4426 0.971 0.901,1.05 760 7602 0.4677 0.973 0.902,1.05 751 7534
374 Other disorders of eyelids sense organs Both 0.1291 0.979 0.953,1.01 5680 56807 0.182 0.967 0.922,1.02 1811 18058
374.1 Ectropion or entropion sense organs Both 0.9954 1.0 0.939,1.06 1063 10645 0.9354 1.0 0.942,1.07 1047 10504
374.3 Ptosis of eyelid sense organs Both 0.2061 0.969 0.923,1.02 1825 18232 0.182 0.967 0.922,1.02 1811 18058
375 Disorders of lacrimal system sense organs Both 0.9354 0.998 0.955,1.04 2204 22031 0.6209 0.983 0.917,1.05 890 8880
375.2 Epiphora sense organs Both 0.5902 0.981 0.915,1.05 898 8969 0.6209 0.983 0.917,1.05 890 8880
376 Disorders of the orbit sense organs Both 0.8872 1.02 0.817,1.26 86 859 0.9057 1.01 0.814,1.26 85 854
377 Disorders of optic nerve and visual pathways sense organs Both 0.1479 1.09 0.972,1.21 361 3618 0.16 1.14 0.948,1.38 124 1242
377.1 Optic atrophy sense organs Both 0.02188 1.34 1.04,1.73 56 570 0.02188 1.35 1.04,1.74 55 568
377.3 Optic neuritis/neuropathy sense organs Both 0.1742 1.14 0.945,1.37 125 1249 0.16 1.14 0.948,1.38 124 1242
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.6808 1.01 0.958,1.07 1410 14116 0.9908 0.999 0.881,1.13 271 2731
378.1 Strabismus (not specified as paralytic) sense organs Both 0.455 1.03 0.959,1.1 909 9082 0.4581 1.03 0.958,1.1 898 9014
378.2 Nystagmus and other irregular eye movements sense organs Both 0.8472 1.01 0.88,1.17 213 2138 0.7962 1.02 0.884,1.17 209 2117
378.5 Paralytic strabismus sense organs Both 0.859 0.989 0.872,1.12 275 2755 0.9908 0.999 0.881,1.13 271 2731
379 Other disorders of eye sense organs Both 0.9931 1.0 0.967,1.03 3703 37063 0.9772 1.0 0.856,1.17 167 1676
379.2 Disorders of vitreous body sense organs Both 0.3083 1.03 0.974,1.09 1367 13665 0.3548 1.03 0.971,1.09 1351 13546
379.3 Aphakia and other disorders of lens sense organs Both 0.4027 0.979 0.933,1.03 1813 18134 0.3963 0.979 0.932,1.03 1791 17949
379.4 Anomalies of pupillary function sense organs Both 0.5284 0.925 0.725,1.18 71 710 0.526 0.924 0.724,1.18 71 703
379.5 Disorders of iris and ciliary body sense organs Both 0.2244 0.939 0.848,1.04 400 4028 0.2046 0.936 0.846,1.04 399 3999
379.9 Pain, swelling or discharge of eye sense organs Both 0.8337 0.983 0.84,1.15 169 1690 0.9772 1.0 0.856,1.17 167 1676
380 Disorders of external ear sense organs Both 0.1276 0.939 0.865,1.02 642 6413 0.257 0.938 0.84,1.05 357 3574
380.1 Otitis externa sense organs Both 0.5346 0.972 0.887,1.06 509 5107 0.5598 0.973 0.888,1.07 503 5070
380.4 Impacted cerumen sense organs Both 0.2851 0.942 0.844,1.05 362 3614 0.257 0.938 0.84,1.05 357 3574
381 Otitis media and Eustachian tube disorders sense organs Both 0.9311 0.998 0.955,1.04 2150 21493 0.0955 1.11 0.982,1.25 275 2789
381.1 Otitis media sense organs Both 0.52 0.984 0.937,1.03 1767 17668 0.5105 1.02 0.954,1.1 836 8471
381.11 Suppurative and unspecified otitis media sense organs Both 0.4853 1.03 0.956,1.1 852 8524 0.5105 1.02 0.954,1.1 836 8471
381.2 Eustachian tube disorders sense organs Both 0.3524 0.934 0.808,1.08 193 1929 0.4121 0.941 0.814,1.09 191 1921
381.3 Mastoiditis & related conditions sense organs Both 0.09772 1.14 0.977,1.33 171 1709 0.1393 1.13 0.962,1.32 167 1697
381.9 Otorrhea sense organs Both 0.08913 1.11 0.984,1.25 281 2807 0.0955 1.11 0.982,1.25 275 2789
382 Otalgia sense organs Both 0.1419 1.09 0.971,1.23 308 3084 0.1483 1.09 0.969,1.23 300 3058
383 Otosclerosis sense organs Both 0.2518 1.07 0.953,1.2 309 3090 0.246 1.07 0.954,1.2 308 3073
384 Other disorders of tympanic membrane sense organs Both 0.3357 1.03 0.971,1.09 1299 12991 0.0166 1.08 1.01,1.15 1034 10354
384.4 Perforation of tympanic membrane sense organs Both 0.01514 1.08 1.02,1.15 1043 10432 0.0166 1.08 1.01,1.15 1034 10354
385 Other disorders of middle ear and mastoid sense organs Both 0.826 1.01 0.937,1.08 783 7837 0.6808 0.972 0.849,1.11 238 2393
385.3 Cholesteatoma sense organs Both 0.5821 1.02 0.943,1.11 607 6078 0.4634 1.03 0.95,1.12 600 6026
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.673 0.972 0.85,1.11 241 2409 0.6808 0.972 0.849,1.11 238 2393
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.8299 1.01 0.957,1.06 1736 17373 0.7079 0.994 0.964,1.03 4499 45426
386.1 Meniere's disease sense organs Both 0.9441 0.997 0.914,1.09 576 5768 0.9661 0.998 0.915,1.09 572 5714
386.2 Peripheral or central vertigo sense organs Both 0.9795 0.999 0.898,1.11 377 3763 0.9462 0.996 0.896,1.11 376 3737
386.3 Labyrinthitis sense organs Both 0.5649 1.02 0.949,1.1 765 7664 0.5649 1.02 0.949,1.1 762 7600
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.873 0.998 0.968,1.03 4582 45806 0.7079 0.994 0.964,1.03 4499 45426
388 Other disorders of ear sense organs Both 0.5224 0.954 0.824,1.1 202 2017 0.4775 0.948 0.818,1.1 197 2004
389 Hearing loss sense organs Both 0.2506 0.982 0.951,1.01 4188 41944 0.8453 1.01 0.923,1.1 504 5082
389.1 Sensorineural hearing loss sense organs Both 0.3698 1.04 0.95,1.15 456 4553 0.3606 1.05 0.95,1.15 451 4520
389.2 Conductive hearing loss sense organs Both 0.6577 1.02 0.927,1.13 450 4497 0.6592 1.02 0.927,1.13 444 4470
389.4 Tinnitus sense organs Both 0.8279 1.01 0.924,1.1 513 5134 0.8453 1.01 0.923,1.1 504 5082
394 Rheumatic disease of the heart valves circulatory system Both 0.2333 1.02 0.989,1.05 4899 48974 0.02239 1.08 1.01,1.15 1034 10454
394.2 Mitral valve disease circulatory system Both 0.526 1.01 0.975,1.05 2993 29922 0.4102 1.02 0.978,1.06 2939 29623
394.3 Aortic valve disease circulatory system Both 0.05248 1.06 0.999,1.12 1282 12814 0.03388 1.06 1.0,1.13 1251 12669
394.7 Disease of tricuspid valve circulatory system Both 0.02512 1.07 1.01,1.14 1058 10566 0.02239 1.08 1.01,1.15 1034 10454
395 Heart valve disorders circulatory system Both 0.6427 1.01 0.976,1.04 4223 42219 0.4909 0.981 0.93,1.04 1465 14776
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.3999 1.02 0.978,1.06 2891 28900 0.3141 1.02 0.981,1.06 2839 28617
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.3069 1.06 0.944,1.2 276 2766 0.2871 1.07 0.946,1.21 267 2739
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.6516 1.05 0.862,1.27 105 1039 0.695 1.04 0.856,1.26 103 1025
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.2438 1.13 0.921,1.38 97 970 0.2642 1.12 0.916,1.38 96 962
395.6 Heart valve replaced circulatory system Both 0.4416 0.979 0.929,1.03 1495 14942 0.4909 0.981 0.93,1.04 1465 14776
396 Abnormal heart sounds circulatory system Both 0.257 1.04 0.974,1.1 1048 10468 0.2148 1.04 0.977,1.11 1038 10381
401 Hypertension circulatory system Both 0.4355 1.0 0.995,1.01 73956 266957 0.5284 0.945 0.792,1.13 140 1425
401.1 Essential hypertension circulatory system Both 0.4831 1.0 0.995,1.01 73731 266739 0.6934 1.0 0.993,1.01 72617 265342
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.3319 1.02 0.977,1.07 1898 19031 0.2636 1.03 0.978,1.09 1513 15353
401.21 Hypertensive heart disease circulatory system Both 0.6324 1.03 0.922,1.14 370 3699 0.6637 1.02 0.919,1.14 362 3663
401.22 Hypertensive chronic kidney disease circulatory system Both 0.3451 1.03 0.973,1.08 1543 15483 0.2636 1.03 0.978,1.09 1513 15353
401.3 Other hypertensive complications circulatory system Both 0.4613 0.936 0.786,1.12 144 1438 0.5284 0.945 0.792,1.13 140 1425
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.5445 1.02 0.964,1.07 1479 14786 0.6934 1.01 0.958,1.07 1461 14665
411 Ischemic Heart Disease circulatory system Both 0.1754 0.992 0.98,1.0 31245 210714 0.6053 0.984 0.927,1.04 1192 12067
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.171 0.98 0.953,1.01 5152 51498 0.1766 0.98 0.952,1.01 5074 51034
411.2 Myocardial infarction circulatory system Both 0.8241 0.998 0.979,1.02 11950 112699 0.7889 0.997 0.979,1.02 11691 111662
411.3 Angina pectoris circulatory system Both 0.06026 0.984 0.968,1.0 15888 143745 0.05495 0.984 0.968,1.0 15604 142478
411.4 Coronary atherosclerosis circulatory system Both 0.4864 0.995 0.98,1.01 20171 154621 0.3281 1.04 0.962,1.12 691 6954
411.41 Aneurysm and dissection of heart circulatory system Both 0.3963 1.03 0.957,1.12 700 6997 0.3281 1.04 0.962,1.12 691 6954
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.3221 0.992 0.975,1.01 15290 131798 0.2483 0.99 0.973,1.01 14881 130604
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.6383 0.986 0.929,1.05 1218 12166 0.6053 0.984 0.927,1.04 1192 12067
414 Other forms of chronic heart disease circulatory system Both 0.0912 1.04 0.993,1.09 1823 18228 0.3758 0.895 0.701,1.14 66 710
414.2 ASCVD circulatory system Both 0.414 0.907 0.718,1.15 72 719 0.3758 0.895 0.701,1.14 66 710
415 Pulmonary heart disease circulatory system Both 0.00166 1.05 1.02,1.08 4476 44810 0.3656 1.05 0.948,1.16 428 4430
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.7727 0.966 0.761,1.23 75 750 0.7586 0.962 0.753,1.23 71 741
415.2 Chronic pulmonary heart disease circulatory system Both 0.0912 1.07 0.989,1.17 601 6002 0.3656 1.05 0.948,1.16 428 4430
415.21 Primary pulmonary hypertension circulatory system Both 0.2924 1.05 0.956,1.16 448 4475 0.3656 1.05 0.948,1.16 428 4430
416 Cardiomegaly circulatory system Both 0.6295 1.01 0.971,1.05 2680 26793 0.6699 1.01 0.969,1.05 2625 26510
418 Nonspecific chest pain circulatory system Both 0.5082 0.996 0.984,1.01 28599 270106 0.7345 0.994 0.96,1.03 3502 35282
418.1 Precordial pain circulatory system Both 0.7534 0.994 0.961,1.03 3551 35541 0.7345 0.994 0.96,1.03 3502 35282
420 Carditis circulatory system Both 0.8017 0.994 0.951,1.04 2106 21053 0.4055 0.968 0.896,1.05 710 7123
420.1 Myocarditis circulatory system Both 0.1968 0.882 0.729,1.07 127 1267 0.228 0.889 0.734,1.08 125 1254
420.2 Pericarditis circulatory system Both 0.9977 1.0 0.945,1.06 1338 13371 0.07762 1.19 0.981,1.44 113 1120
420.21 Acute pericarditis circulatory system Both 0.04169 0.863 0.75,0.994 223 2227 0.02754 0.851 0.737,0.982 216 2211
420.22 Chronic pericarditis circulatory system Both 0.08318 1.18 0.978,1.43 113 1129 0.07762 1.19 0.981,1.44 113 1120
420.3 Endocarditis circulatory system Both 0.4246 0.969 0.898,1.05 719 7194 0.4055 0.968 0.896,1.05 710 7123
425 Cardiomyopathy circulatory system Both 0.4966 1.02 0.963,1.08 1271 12699 0.6039 1.07 0.826,1.39 58 594
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.5916 1.02 0.958,1.08 1236 12349 0.9977 1.0 0.852,1.17 159 1618
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.9141 0.99 0.831,1.18 133 1329 0.9078 0.989 0.828,1.18 129 1317
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.8974 1.01 0.863,1.18 163 1629 0.9977 1.0 0.852,1.17 159 1618
425.8 Other cardiomyopathy circulatory system Both 0.7727 1.04 0.803,1.34 60 600 0.6039 1.07 0.826,1.39 58 594
426 Cardiac conduction disorders circulatory system Both 0.2472 1.01 0.99,1.04 6910 69146 0.114 1.04 0.992,1.08 2234 22531
426.2 Atrioventricular [AV] block circulatory system Both 0.778 0.994 0.95,1.04 2114 21162 0.8017 1.02 0.854,1.23 129 1303
426.21 First degree AV block circulatory system Both 0.3767 0.971 0.909,1.04 986 9867 0.413 0.973 0.911,1.04 975 9763
426.23 Second degree AV block circulatory system Both 0.4864 1.03 0.94,1.14 452 4515 0.4102 1.04 0.945,1.15 448 4475
426.24 Atrioventricular block, complete circulatory system Both 0.6095 1.02 0.939,1.11 587 5868 0.7278 1.02 0.931,1.11 579 5809
426.25 Other heart block circulatory system Both 0.6039 1.05 0.876,1.25 131 1318 0.8017 1.02 0.854,1.23 129 1303
426.3 Bundle branch block circulatory system Both 0.9441 0.999 0.964,1.03 3336 33359 0.8299 1.01 0.957,1.06 1723 17344
426.31 Right bundle branch block circulatory system Both 0.8395 1.01 0.954,1.06 1494 14933 0.9795 0.999 0.947,1.05 1452 14797
426.32 Left bundle branch block circulatory system Both 0.7516 1.01 0.96,1.06 1750 17503 0.8299 1.01 0.957,1.06 1723 17344
426.4 Anomalous atrioventricular excitation circulatory system Both 0.03715 0.866 0.757,0.991 233 2328 0.03715 0.867 0.757,0.992 233 2315
426.8 Other cardiac conduction disorders circulatory system Both 0.4775 1.1 0.85,1.41 60 600 0.5848 1.07 0.831,1.39 59 595
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.05129 1.04 1.0,1.09 2475 24774 0.114 1.04 0.992,1.08 2234 22531
426.91 Cardiac pacemaker in situ circulatory system Both 0.04266 1.05 1.0,1.09 2274 22762 0.114 1.04 0.992,1.08 2234 22531
427 Cardiac dysrhythmias circulatory system Both 0.1119 1.01 0.997,1.02 24207 206016 0.3192 1.02 0.984,1.05 3764 37861
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.7925 1.0 0.969,1.04 3199 32017 0.6486 1.02 0.949,1.09 922 9275
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.9705 0.999 0.958,1.04 2344 23474 0.9683 0.999 0.957,1.04 2306 23310
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.7311 1.01 0.946,1.08 936 9365 0.6486 1.02 0.949,1.09 922 9275
427.2 Atrial fibrillation and flutter circulatory system Both 0.2328 1.01 0.993,1.03 14628 133501 0.3899 1.01 0.99,1.03 14243 132340
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.2228 1.02 0.986,1.06 3228 32281 0.2415 1.02 0.986,1.06 3184 32023
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.07244 1.06 0.995,1.12 1193 11915 0.2667 1.04 0.972,1.11 950 9793
427.41 Ventricular fibrillation and flutter circulatory system Both 0.0631 1.11 0.995,1.24 344 3437 0.07762 1.1 0.989,1.23 342 3415
427.42 Cardiac arrest circulatory system Both 0.2553 1.04 0.973,1.11 990 9890 0.2667 1.04 0.972,1.11 950 9793
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.9183 1.0 0.939,1.07 952 9541 0.873 1.01 0.94,1.08 941 9460
427.6 Premature beats circulatory system Both 0.8185 1.01 0.924,1.11 535 5358 0.6577 0.957 0.789,1.16 115 1158
427.61 Supraventricular premature beats circulatory system Both 0.7568 0.97 0.801,1.18 117 1168 0.6577 0.957 0.789,1.16 115 1158
427.7 Tachycardia NOS circulatory system Both 0.6855 1.01 0.966,1.05 2185 21865 0.8395 0.995 0.952,1.04 2082 21698
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.5702 1.03 0.93,1.14 402 4029 0.5559 1.03 0.93,1.14 395 3996
427.9 Palpitations circulatory system Both 0.3443 1.02 0.983,1.05 3811 38105 0.3192 1.02 0.984,1.05 3764 37861
428 Congestive heart failure; nonhypertensive circulatory system Both 0.5902 1.01 0.98,1.04 5605 56018 0.2649 1.02 0.987,1.05 4326 43992
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.9226 1.0 0.958,1.05 2111 21108 0.871 0.996 0.952,1.04 2033 20864
428.2 Heart failure NOS circulatory system Both 0.2042 1.02 0.989,1.05 4455 44524 0.2649 1.02 0.987,1.05 4326 43992
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.07586 0.933 0.864,1.01 716 7168 0.7943 0.981 0.849,1.13 194 1963
429.1 Heart transplant/surgery circulatory system Both 0.5572 0.927 0.721,1.19 64 639 0.5559 0.925 0.714,1.2 60 635
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.07413 0.921 0.842,1.01 522 5211 0.04266 0.91 0.832,0.997 515 5168
429.3 Symptoms involving cardiovascular system circulatory system Both 0.7762 0.979 0.848,1.13 196 1978 0.7943 0.981 0.849,1.13 194 1963
430 Intracranial hemorrhage circulatory system Both 0.09772 1.04 0.993,1.09 1883 18825 0.9268 1.01 0.888,1.14 262 2638
430.1 Subarachnoid hemorrhage circulatory system Both 0.01445 1.09 1.02,1.17 836 8353 0.0195 1.09 1.01,1.17 822 8309
430.2 Intracerebral hemorrhage circulatory system Both 0.6501 1.02 0.944,1.1 765 7656 0.7345 1.01 0.94,1.09 748 7566
430.3 Subdural hemorrhage circulatory system Both 0.865 1.01 0.894,1.14 267 2667 0.9268 1.01 0.888,1.14 262 2638
433 Cerebrovascular disease circulatory system Both 0.009772 1.03 1.01,1.05 8749 87456 0.4315 1.02 0.966,1.08 1235 12643
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.4775 1.02 0.963,1.09 1185 11825 0.7516 1.02 0.891,1.17 220 2238
433.12 Cerebral atherosclerosis circulatory system Both 0.7015 1.03 0.897,1.18 227 2267 0.7516 1.02 0.891,1.17 220 2238
433.2 Occlusion of cerebral arteries circulatory system Both 0.6442 1.01 0.976,1.04 4233 42320 0.3334 1.03 0.974,1.08 1624 16613
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.3076 1.03 0.976,1.08 1680 16794 0.3334 1.03 0.974,1.08 1624 16613
433.3 Cerebral ischemia circulatory system Both 0.003715 1.06 1.02,1.1 2895 28989 0.03236 1.05 1.0,1.1 2087 21163
433.31 Transient cerebral ischemia circulatory system Both 0.03236 1.05 1.0,1.1 2135 21379 0.03236 1.05 1.0,1.1 2087 21163
433.5 Cerebral aneurysm circulatory system Both 0.05012 1.11 1.0,1.23 394 3939 0.0631 1.1 0.994,1.23 386 3901
433.8 Late effects of cerebrovascular disease circulatory system Both 0.3855 1.03 0.969,1.09 1279 12783 0.4315 1.02 0.966,1.08 1235 12643
440 Atherosclerosis circulatory system Both 0.001175 1.1 1.04,1.16 1380 13822 0.04266 1.14 1.0,1.29 272 2837
440.1 Atherosclerosis of renal artery circulatory system Both 0.8433 1.02 0.841,1.24 113 1129 0.8453 1.02 0.841,1.24 113 1120
440.2 Atherosclerosis of the extremities circulatory system Both 0.00309 1.12 1.04,1.2 805 8070 0.003631 1.12 1.04,1.2 776 7988
440.9 Atherosclerosis of aorta circulatory system Both 0.03311 1.14 1.01,1.29 287 2867 0.04266 1.14 1.0,1.29 272 2837
441 Vascular insufficiency of intestine circulatory system Both 0.3622 1.04 0.957,1.13 614 6154 0.07244 1.12 0.99,1.26 281 2792
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.07586 1.12 0.988,1.26 283 2827 0.07244 1.12 0.99,1.26 281 2792
442 Other aneurysm circulatory system Both 6.607E-5 1.1 1.05,1.15 1892 18959 0.0195 1.19 1.03,1.38 198 2013
442.1 Aortic aneurysm circulatory system Both 0.00195 1.09 1.03,1.15 1458 14625 0.02692 1.08 1.01,1.16 880 9230
442.11 Abdominal aortic aneurysm circulatory system Both 0.01549 1.09 1.02,1.16 931 9341 0.02692 1.08 1.01,1.16 880 9230
442.2 Aneurysm of iliac artery circulatory system Both 0.2148 1.13 0.93,1.38 102 1019 0.2553 1.12 0.918,1.38 96 1005
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.07079 1.15 0.988,1.34 169 1696 0.1 1.14 0.975,1.34 161 1672
442.4 Arterial dissection circulatory system Both 0.3388 1.14 0.875,1.47 54 549 0.3162 1.14 0.88,1.48 54 544
442.8 Aneurysm of other specified artery circulatory system Both 0.0138 1.2 1.04,1.38 203 2028 0.0195 1.19 1.03,1.38 198 2013
443 Peripheral vascular disease circulatory system Both 3.981E-8 1.1 1.06,1.13 3921 39273 1.349E-5 1.1 1.05,1.14 2430 25565
443.1 Raynaud's syndrome circulatory system Both 0.006761 1.09 1.02,1.15 1145 11438 0.008913 1.08 1.02,1.15 1124 11366
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.1493 1.08 0.973,1.2 384 3878 0.1589 1.08 0.971,1.2 377 3829
443.8 Other specified peripheral vascular diseases circulatory system Both 1.95E-8 1.1 1.06,1.14 3686 36906 6.026E-7 1.09 1.05,1.13 3519 36547
443.9 Peripheral vascular disease, unspecified circulatory system Both 5.37E-7 1.11 1.06,1.15 2579 25846 1.349E-5 1.1 1.05,1.14 2430 25565
444 Arterial embolism and thrombosis circulatory system Both 3.467E-4 1.13 1.06,1.21 922 9251 6.166E-5 1.2 1.1,1.31 523 5489
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 8.318E-5 1.19 1.09,1.3 554 5552 6.166E-5 1.2 1.1,1.31 523 5489
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.2148 1.05 0.974,1.12 822 8226 0.5998 1.04 0.907,1.18 233 2386
446.4 Wegener's granulomatosis circulatory system Both 0.3673 1.07 0.924,1.24 188 1878 0.514 1.05 0.907,1.22 185 1861
446.5 Giant cell arteritis circulatory system Both 0.4592 1.04 0.938,1.15 388 3879 0.3733 1.05 0.945,1.16 383 3840
446.9 Arteritis NOS circulatory system Both 0.5212 1.04 0.915,1.19 239 2400 0.5998 1.04 0.907,1.18 233 2386
447 Other disorders of arteries and arterioles circulatory system Both 9.772E-4 1.1 1.04,1.16 1327 13316 0.01288 1.09 1.02,1.17 833 8611
447.1 Stricture of artery circulatory system Both 0.004571 1.1 1.03,1.18 868 8712 0.01288 1.09 1.02,1.17 833 8611
448 Disease of capillaries circulatory system Both 0.9204 1.01 0.846,1.2 142 1420 0.9268 1.01 0.844,1.2 140 1412
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.7586 1.01 0.937,1.09 704 7034 0.9977 1.0 0.924,1.08 670 6974
451 Phlebitis and thrombophlebitis circulatory system Both 0.8851 0.998 0.966,1.03 3955 39683 0.6637 0.992 0.959,1.03 3564 36661
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.9661 1.0 0.967,1.04 3683 36977 0.6637 0.992 0.959,1.03 3564 36661
452 Other venous embolism and thrombosis circulatory system Both 0.7311 1.02 0.93,1.11 564 5645 0.9616 0.998 0.912,1.09 537 5595
454 Varicose veins circulatory system Both 0.955 1.0 0.981,1.02 11180 112047 0.3516 1.04 0.958,1.13 613 6282
454.1 Varicose veins of lower extremity circulatory system Both 0.6095 1.01 0.986,1.02 11503 115272 0.3516 1.04 0.958,1.13 613 6282
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.3715 1.04 0.956,1.13 624 6325 0.3516 1.04 0.958,1.13 613 6282
455 Hemorrhoids circulatory system Both 0.7998 0.998 0.985,1.01 23452 234585 0.9162 0.999 0.986,1.01 23233 232911
456 Chronic venous insufficiency [CVI] circulatory system Both 0.9506 0.995 0.86,1.15 184 1868 0.9705 1.0 0.866,1.16 182 1855
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.7112 0.961 0.78,1.18 97 967 0.6471 0.952 0.772,1.17 96 957
458 Hypotension circulatory system Both 0.1626 1.02 0.992,1.05 5769 57772 0.2673 1.02 0.985,1.06 3375 34708
458.1 Orthostatic hypotension circulatory system Both 0.5715 1.02 0.961,1.08 1335 13376 0.6871 1.01 0.956,1.07 1292 13239
458.2 Iatrogenic hypotension circulatory system Both 0.3236 1.07 0.936,1.22 235 2348 0.3681 1.06 0.929,1.22 228 2329
458.9 Hypotension NOS circulatory system Both 0.1426 1.03 0.991,1.06 3494 35005 0.2673 1.02 0.985,1.06 3375 34708
459 Other disorders of circulatory system circulatory system Both 0.006918 1.02 1.01,1.04 16268 160790 0.02344 1.02 1.0,1.04 15651 158156
459.1 Hemorrhage NOS circulatory system Both 0.0389 0.83 0.696,0.99 142 1420 0.08511 0.854 0.713,1.02 135 1403
459.9 Circulatory disease NEC circulatory system Both 0.004365 1.02 1.01,1.04 16103 159422 0.02344 1.02 1.0,1.04 15651 158156
464 Acute sinusitis respiratory Both 0.695 0.971 0.836,1.13 196 1957 0.7194 0.973 0.838,1.13 196 1947
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.912 0.998 0.956,1.04 2283 22827 0.9886 1.0 0.847,1.18 150 1635
465.2 Acute pharyngitis respiratory Both 0.5834 0.98 0.914,1.05 835 8348 0.5321 0.978 0.91,1.05 814 8295
465.4 Acute laryngitis and tracheitis respiratory Both 0.865 1.01 0.864,1.19 165 1649 0.9886 1.0 0.847,1.18 150 1635
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.2173 0.981 0.952,1.01 4654 46553 0.2477 0.982 0.953,1.01 4618 46294
471 Nasal polyps respiratory Both 0.7603 1.01 0.97,1.04 3297 32973 0.811 1.0 0.969,1.04 3269 32726
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.6039 1.02 0.953,1.09 960 9594 0.6745 1.01 0.949,1.08 944 9524
473 Diseases of the larynx and vocal cords respiratory Both 0.08913 1.04 0.995,1.08 2554 25548 0.2032 1.04 0.978,1.11 1015 10700
473.1 Chronic laryngitis respiratory Both 0.2685 1.12 0.918,1.36 104 1038 0.2466 1.13 0.921,1.38 96 1030
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.6902 1.03 0.906,1.16 264 2647 0.975 1.0 0.878,1.14 231 2616
473.4 Voice disturbance respiratory Both 0.1 1.05 0.99,1.12 1080 10789 0.2032 1.04 0.978,1.11 1015 10700
474 Acute and chronic tonsillitis respiratory Both 0.4198 0.98 0.933,1.03 1772 17710 0.9016 1.0 0.944,1.07 1112 11154
474.1 Acute tonsillitis respiratory Both 0.00955 0.89 0.815,0.972 549 5486 0.009333 0.889 0.814,0.972 544 5466
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.9183 1.0 0.944,1.07 1122 11199 0.9016 1.0 0.944,1.07 1112 11154
475 Chronic sinusitis respiratory Both 0.09333 0.966 0.927,1.01 2589 25882 0.1161 0.968 0.929,1.01 2572 25715
476 Allergic rhinitis respiratory Both 0.278 0.965 0.906,1.03 1055 10563 0.3243 0.968 0.908,1.03 1046 10505
477 Epistaxis or throat hemorrhage respiratory Both 0.07586 0.963 0.923,1.0 2447 24452 0.0302 0.954 0.914,0.996 2379 24235
478 Throat pain respiratory Both 0.8995 1.01 0.906,1.12 377 3789 0.8492 1.01 0.909,1.12 371 3756
479 Other upper respiratory disease respiratory Both 0.02754 1.04 1.0,1.07 4074 40737 0.03162 1.04 1.0,1.07 3936 40467
480 Pneumonia respiratory Both 4.074E-4 1.04 1.02,1.06 10336 103397 0.5689 1.02 0.946,1.11 682 7872
480.1 Bacterial pneumonia respiratory Both 7.943E-4 1.04 1.02,1.07 6637 66410 0.5058 0.93 0.751,1.15 85 923
480.11 Pneumococcal pneumonia respiratory Both 0.002455 1.04 1.01,1.07 5883 58863 0.08511 1.02 0.997,1.05 5415 58408
480.12 Pseudomonal pneumonia respiratory Both 0.929 1.01 0.822,1.24 93 929 0.5058 0.93 0.751,1.15 85 923
480.2 Viral pneumonia respiratory Both 0.2655 0.874 0.691,1.11 72 720 0.2965 0.881 0.695,1.12 71 719
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.1393 0.854 0.693,1.05 99 989 0.08913 0.827 0.665,1.03 91 982
480.5 Bronchopneumonia and lung abscess respiratory Both 0.08511 1.07 0.991,1.15 794 7951 0.5689 1.02 0.946,1.11 682 7872
481 Influenza respiratory Both 0.6486 1.03 0.918,1.15 328 3278 0.8128 1.01 0.905,1.14 318 3265
483 Acute bronchitis and bronchiolitis respiratory Both 0.9506 0.995 0.861,1.15 193 1930 0.9616 0.996 0.861,1.15 189 1923
495 Asthma respiratory Both 0.138 1.01 0.997,1.02 25689 250406 0.9057 1.01 0.887,1.15 245 2495
495.2 Asthma with exacerbation respiratory Both 0.7516 1.02 0.899,1.16 250 2510 0.9057 1.01 0.887,1.15 245 2495
496 Chronic airway obstruction respiratory Both 2.692E-4 1.04 1.02,1.06 10424 101546 0.2056 0.969 0.924,1.02 1822 18724
496.1 Emphysema respiratory Both 1.175E-5 1.12 1.06,1.17 1743 17438 0.001445 1.09 1.03,1.15 1504 17298
496.2 Chronic bronchitis respiratory Both 2.089E-5 1.09 1.05,1.13 2947 29498 0.005754 1.06 1.02,1.1 2424 26838
496.21 Obstructive chronic bronchitis respiratory Both 1.445E-5 1.09 1.05,1.13 2706 27081 0.005754 1.06 1.02,1.1 2424 26838
496.3 Bronchiectasis respiratory Both 0.3597 0.978 0.933,1.03 1885 18859 0.2056 0.969 0.924,1.02 1822 18724
497 Bronchitis respiratory Both 0.9057 1.0 0.926,1.09 626 6267 0.857 1.01 0.927,1.1 593 6229
500 Lung disease due to external agents respiratory Both 0.4909 1.04 0.937,1.15 412 4099 0.5794 1.04 0.905,1.2 215 2385
500.1 Extrinsic allergic alveolitis respiratory Both 0.3819 0.898 0.706,1.14 79 784 0.4831 0.916 0.718,1.17 77 780
500.2 Pneumoconiosis respiratory Both 0.1439 1.1 0.967,1.26 243 2409 0.5794 1.04 0.905,1.2 215 2385
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.5702 1.02 0.946,1.11 656 6557 0.6699 1.02 0.938,1.1 614 6511
502 Postinflammatory pulmonary fibrosis respiratory Both 0.2649 0.962 0.898,1.03 917 9193 0.3083 0.964 0.897,1.03 833 9113
503 Pulmonary congestion and hypostasis respiratory Both 0.7345 1.02 0.927,1.11 508 5079 0.9772 1.0 0.913,1.1 489 5045
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.7834 1.02 0.908,1.14 328 3280 0.9268 0.995 0.887,1.12 315 3256
505 Other pulmonary inflamation or edema respiratory Both 0.9354 1.01 0.781,1.31 61 610 0.8995 1.02 0.785,1.32 60 609
506 Empyema and pneumothorax respiratory Both 1.349E-4 1.13 1.06,1.2 1133 11362 0.002951 1.1 1.03,1.18 967 11302
507 Pleurisy; pleural effusion respiratory Both 0.03236 1.03 1.0,1.06 6419 64252 0.7534 1.0 0.978,1.03 5744 63823
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.2851 1.03 0.979,1.07 1996 19947 0.8072 1.01 0.959,1.06 1802 19832
509 Respiratory failure, insufficiency, arrest respiratory Both 0.02818 1.05 1.0,1.09 2599 26031 0.7889 0.985 0.886,1.1 367 3835
509.1 Respiratory failure respiratory Both 0.002239 1.07 1.03,1.12 2068 20708 0.02188 1.06 1.01,1.11 1905 20564
509.2 Respiratory insufficiency respiratory Both 0.003715 1.07 1.02,1.13 1806 18106 0.02089 1.06 1.01,1.12 1666 17987
509.5 Respiratory arrest respiratory Both 0.1074 1.15 0.97,1.36 143 1429 0.2438 1.11 0.932,1.32 133 1416
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.5284 0.967 0.871,1.07 386 3863 0.7889 0.985 0.886,1.1 367 3835
510 Other diseases of lung respiratory Both 0.3281 1.04 0.963,1.12 755 7554 0.955 1.0 0.921,1.09 599 7482
512 Other symptoms of respiratory system respiratory Both 0.302 1.01 0.99,1.03 9031 90349 0.1321 1.05 0.984,1.13 894 9041
512.1 Wheezing respiratory Both 0.4027 0.941 0.816,1.09 220 2196 0.369 0.935 0.807,1.08 207 2176
512.2 Painful respiration respiratory Both 0.3062 1.08 0.935,1.24 207 2075 0.3936 1.06 0.922,1.23 199 2060
512.7 Shortness of breath respiratory Both 0.4943 1.01 0.983,1.04 5842 58498 0.9572 1.0 0.974,1.03 5593 58040
512.8 Cough respiratory Both 0.8072 1.0 0.967,1.04 2866 28642 0.9528 1.0 0.963,1.04 2724 28425
512.9 Other dyspnea respiratory Both 0.07244 1.06 0.994,1.14 914 9124 0.1321 1.05 0.984,1.13 894 9041
513 Respiratory abnormalities respiratory Both 0.7638 1.01 0.933,1.1 611 6112 0.06918 0.854 0.721,1.01 148 1524
513.3 Hypoventilation respiratory Both 0.3664 0.902 0.721,1.13 83 830 0.2547 0.875 0.696,1.1 79 820
513.4 Hyperventilation respiratory Both 0.0955 1.11 0.982,1.25 278 2778 0.2897 1.07 0.944,1.21 266 2757
513.8 Disorders of diaphragm respiratory Both 0.07586 0.86 0.727,1.02 153 1538 0.06918 0.854 0.721,1.01 148 1524
514 Abnormal findings examination of lungs respiratory Both 8.511E-4 1.07 1.03,1.12 2465 24673 0.5105 1.02 0.969,1.07 1807 24469
516 Abnormal sputum respiratory Both 0.01905 1.05 1.01,1.1 2132 21335 0.07244 1.04 0.996,1.1 1869 20565
516.1 Hemoptysis respiratory Both 0.00955 1.06 1.01,1.11 2073 20745 0.07244 1.04 0.996,1.1 1869 20565
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.3873 1.01 0.988,1.03 9366 93681 0.09772 1.11 0.981,1.25 285 3033
519.2 Respiratory complications respiratory Both 0.8318 0.988 0.883,1.11 327 3279 0.4198 0.95 0.838,1.08 263 3251
519.8 Other diseases of respiratory system, NEC respiratory Both 0.415 1.01 0.987,1.03 8853 88522 0.8453 0.998 0.976,1.02 8340 87841
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.1656 1.09 0.966,1.23 303 3049 0.09772 1.11 0.981,1.25 285 3033
520 Disorders of tooth development digestive Both 0.6039 0.988 0.944,1.03 2038 20354 0.8318 0.995 0.954,1.04 2343 23427
520.1 Hereditary disturbances in tooth structure digestive Both 0.07413 1.28 0.977,1.67 53 530 0.07586 1.27 0.975,1.67 53 527
520.2 Disturbances in tooth eruption digestive Both 0.8072 0.995 0.954,1.04 2356 23539 0.8318 0.995 0.954,1.04 2343 23427
521 Diseases of hard tissues of teeth digestive Both 0.1 1.03 0.994,1.07 3016 30245 0.07586 1.03 0.996,1.07 2987 30161
521.1 Dental caries digestive Both 0.07413 1.03 0.997,1.07 3026 30353 0.07586 1.03 0.996,1.07 2987 30161
522 Diseases of pulp and periapical tissues digestive Both 0.3327 1.02 0.976,1.07 1774 17750 0.7145 0.989 0.931,1.05 1156 11666
522.5 Periapical abscess digestive Both 0.7464 0.99 0.933,1.05 1172 11731 0.7145 0.989 0.931,1.05 1156 11666
523 Gingival and periodontal diseases digestive Both 0.7261 1.01 0.96,1.06 1681 16812 0.597 1.02 0.939,1.12 557 5565
523.1 Gingivitis digestive Both 0.879 1.01 0.838,1.23 113 1127 0.8531 1.02 0.84,1.23 112 1126
523.3 Periodontitis (acute or chronic) digestive Both 0.7656 0.991 0.934,1.05 1165 11650 0.597 1.02 0.939,1.12 557 5565
523.31 Acute periodontitis digestive Both 0.7534 0.987 0.913,1.07 666 6667 0.7834 0.989 0.914,1.07 662 6642
523.32 Chronic periodontitis digestive Both 0.5943 1.02 0.939,1.12 560 5594 0.597 1.02 0.939,1.12 557 5565
524 Dentofacial anomalies, including malocclusion digestive Both 1.0 1.0 0.894,1.12 331 3307 0.9036 1.01 0.895,1.13 302 3028
524.3 Anomalies of tooth position/malocclusion digestive Both 0.9506 1.0 0.893,1.13 305 3046 0.9036 1.01 0.895,1.13 302 3028
525 Other diseases of the teeth and supporting structures digestive Both 0.7852 1.01 0.967,1.05 2668 26728 0.06761 0.79 0.613,1.02 72 714
525.2 Atrophy of edentulous alveolar ridge digestive Both 0.0631 0.786 0.61,1.01 72 720 0.06761 0.79 0.613,1.02 72 714
526 Diseases of the jaws digestive Both 0.8492 0.993 0.929,1.06 928 9279 0.257 1.08 0.945,1.24 227 2309
526.1 Cysts of the jaws digestive Both 0.3508 1.06 0.942,1.18 329 3289 0.3381 1.06 0.944,1.18 327 3268
526.3 Anomalies of jaw size/symmetry digestive Both 0.597 1.07 0.826,1.39 61 610 0.597 1.07 0.826,1.39 61 610
526.4 Temporomandibular joint disorders digestive Both 0.05888 0.881 0.772,1.0 240 2406 0.05129 0.876 0.766,1.0 231 2323
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.04365 0.872 0.763,0.996 233 2336 0.05129 0.876 0.766,1.0 231 2323
526.5 Inflammatory conditions of jaw digestive Both 0.3273 0.908 0.749,1.1 110 1098 0.3048 0.901 0.738,1.1 102 1091
526.9 Jaw disease NOS digestive Both 0.1968 1.09 0.956,1.25 233 2329 0.257 1.08 0.945,1.24 227 2309
527 Diseases of the salivary glands digestive Both 0.4467 1.03 0.953,1.11 694 6943 0.3133 1.1 0.915,1.32 120 1184
527.1 Hypertrophy of salivary gland digestive Both 0.7015 1.04 0.844,1.29 84 838 0.6823 1.05 0.846,1.29 83 832
527.2 Sialoadenitis digestive Both 0.9099 0.994 0.891,1.11 365 3656 0.8933 0.993 0.889,1.11 360 3629
527.7 Disturbance of salivary secretion digestive Both 0.3899 0.891 0.684,1.16 62 619 0.3581 0.882 0.674,1.15 59 614
527.8 Other specified diseases of the salivary glands digestive Both 0.3266 1.1 0.912,1.32 120 1200 0.3133 1.1 0.915,1.32 120 1184
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.03715 1.04 1.0,1.07 3873 38741 0.7691 1.02 0.907,1.14 313 3117
528.1 Stomatitis and mucositis digestive Both 0.7129 1.02 0.925,1.12 468 4675 0.2911 0.883 0.701,1.11 82 834
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.5508 1.03 0.93,1.15 389 3884 0.9772 0.998 0.896,1.11 363 3852
528.12 Oral aphthae digestive Both 0.3199 0.891 0.71,1.12 84 840 0.2911 0.883 0.701,1.11 82 834
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.5495 1.05 0.901,1.22 179 1790 0.5433 1.05 0.901,1.22 174 1778
528.4 Cysts of oral soft tissues digestive Both 0.7962 1.03 0.85,1.24 122 1219 0.4385 1.09 0.879,1.35 94 934
528.41 Cyst of the salivary gland digestive Both 0.4436 1.09 0.878,1.35 94 940 0.4385 1.09 0.879,1.35 94 934
528.5 Diseases of lips digestive Both 0.9462 1.0 0.927,1.08 681 6813 0.8913 1.01 0.929,1.09 677 6764
528.6 Leukoplakia of oral mucosa digestive Both 0.5346 1.04 0.924,1.16 308 3079 0.6607 1.03 0.913,1.15 299 3060
528.7 Sialolithiasis digestive Both 0.7798 1.02 0.907,1.14 314 3138 0.7691 1.02 0.907,1.14 313 3117
529 Diseases and other conditions of the tongue digestive Both 0.3357 1.03 0.971,1.09 1232 12312 0.6324 1.03 0.914,1.16 287 2961
529.1 Glossitis digestive Both 0.547 1.04 0.922,1.16 299 2986 0.6324 1.03 0.914,1.16 287 2961
530 Diseases of esophagus digestive Both 0.4955 0.996 0.985,1.01 33453 279172 0.1629 0.968 0.925,1.01 2066 20729
530.1 Esophagitis, GERD and related diseases digestive Both 0.7079 0.998 0.986,1.01 31253 272429 0.9795 1.0 0.98,1.02 10318 103707
530.11 GERD digestive Both 0.6966 1.0 0.989,1.02 22633 225879 0.673 1.0 0.989,1.02 22343 224268
530.12 Ulcer of esophagus digestive Both 0.859 0.997 0.969,1.03 5203 52068 0.7745 0.996 0.968,1.02 5121 51617
530.14 Reflux esophagitis digestive Both 0.9078 0.999 0.979,1.02 10444 104493 0.9795 1.0 0.98,1.02 10318 103707
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.7015 1.01 0.96,1.06 1681 16808 0.7943 1.01 0.957,1.06 1641 16675
530.3 Stricture and stenosis of esophagus digestive Both 0.6966 0.991 0.944,1.04 1869 18684 0.6427 0.989 0.942,1.04 1814 18524
530.5 Disorders of esophageal motility digestive Both 0.4159 0.967 0.892,1.05 635 6365 0.4083 0.966 0.891,1.05 629 6323
530.6 Diverticulum of esophagus, acquired digestive Both 0.4581 1.06 0.902,1.26 153 1527 0.5888 1.05 0.885,1.24 149 1504
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.1799 0.926 0.828,1.04 341 3416 0.2173 0.931 0.832,1.04 334 3387
530.9 Heartburn digestive Both 0.1578 0.968 0.925,1.01 2087 20881 0.1629 0.968 0.925,1.01 2066 20729
531 Peptic ulcer (excl. esophageal) digestive Both 0.3281 1.01 0.988,1.04 7103 71066 0.04898 1.11 1.0,1.22 413 4226
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.6966 1.02 0.936,1.1 637 6374 0.7413 1.01 0.933,1.1 619 6305
531.2 Gastric ulcer digestive Both 0.3656 1.01 0.983,1.05 4091 40941 0.3648 1.02 0.983,1.05 4031 40562
531.3 Duodenal ulcer digestive Both 0.4406 0.985 0.949,1.02 2999 30005 0.4121 0.984 0.947,1.02 2931 29700
531.4 Peptic ulcer, site unspecified digestive Both 0.06607 1.1 0.994,1.21 427 4268 0.04898 1.11 1.0,1.22 413 4226
532 Dysphagia digestive Both 0.302 1.01 0.988,1.04 6427 64329 0.3846 1.01 0.986,1.04 6251 63836
535 Gastritis and duodenitis digestive Both 0.4875 1.0 0.992,1.02 28078 261548 0.5754 1.05 0.878,1.26 119 1178
535.1 Acute gastritis digestive Both 0.5117 0.98 0.923,1.04 1183 11833 0.5093 0.98 0.922,1.04 1162 11726
535.2 Atrophic gastritis digestive Both 0.2858 1.06 0.953,1.18 370 3687 0.2301 1.07 0.96,1.19 363 3650
535.6 Duodenitis digestive Both 0.1932 1.02 0.992,1.04 7592 75928 0.2023 1.02 0.992,1.04 7456 75282
535.8 Other specified gastritis digestive Both 0.3097 0.988 0.966,1.01 8071 80763 0.3926 0.99 0.967,1.01 7968 80082
535.9 Gastritis and duodenitis, NOS digestive Both 0.5781 1.05 0.878,1.26 120 1191 0.5754 1.05 0.878,1.26 119 1178
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.6998 1.03 0.903,1.16 259 2576 0.7194 1.02 0.9,1.16 255 2559
537 Other disorders of stomach and duodenum digestive Both 0.04365 1.04 1.0,1.07 3391 33907 0.04074 1.04 1.0,1.08 3322 33608
540 Appendiceal conditions digestive Both 0.1002 1.03 0.994,1.07 3088 30890 0.1343 1.03 0.991,1.07 2583 25872
540.1 Appendicitis digestive Both 0.1005 1.03 0.994,1.07 2895 28963 0.1343 1.03 0.991,1.07 2583 25872
540.11 Acute appendicitis digestive Both 0.1291 1.03 0.991,1.07 2601 26019 0.1343 1.03 0.991,1.07 2583 25872
550 Abdominal hernia digestive Both 0.01349 0.987 0.978,0.997 45429 282640 0.5495 0.989 0.955,1.02 3383 34061
550.1 Inguinal hernia digestive Both 0.1426 0.988 0.971,1.0 15794 123247 0.1901 0.989 0.973,1.01 15612 122175
550.2 Diaphragmatic hernia digestive Both 0.03467 0.986 0.974,0.999 26494 238953 0.04467 0.987 0.974,1.0 26202 237143
550.3 Femoral hernia digestive Both 0.6902 1.02 0.938,1.1 651 6504 0.7603 1.01 0.934,1.1 648 6456
550.4 Umbilical hernia digestive Both 0.6339 0.992 0.959,1.03 3705 37072 0.7112 0.994 0.961,1.03 3671 36802
550.5 Ventral hernia digestive Both 0.5916 0.99 0.956,1.03 3435 34338 0.5495 0.989 0.955,1.02 3383 34061
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.4688 0.989 0.959,1.02 4444 44442 0.0955 0.927 0.848,1.01 532 5349
555.1 Regional enteritis digestive Both 0.2046 0.969 0.922,1.02 1734 17340 0.1849 0.967 0.92,1.02 1710 17246
555.2 Ulcerative colitis digestive Both 0.8933 0.997 0.962,1.03 3178 31786 0.0955 0.927 0.848,1.01 532 5349
555.21 Ulcerative colitis (chronic) digestive Both 0.08511 0.925 0.846,1.01 538 5382 0.0955 0.927 0.848,1.01 532 5349
556 Ulceration of the lower GI tract digestive Both 0.08511 0.946 0.888,1.01 1055 10592 0.01778 0.908 0.838,0.983 663 6672
556.1 Ulceration of intestine digestive Both 0.03311 0.917 0.847,0.993 670 6714 0.01778 0.908 0.838,0.983 663 6672
557 Intestinal malabsorption (non-celiac) digestive Both 0.3758 1.05 0.938,1.18 299 2987 1.995E-49 1.44 1.37,1.51 1827 18263
557.1 Celiac disease digestive Both 2.512E-49 1.43 1.37,1.5 1837 18388 1.995E-49 1.44 1.37,1.51 1827 18263
558 Noninfectious gastroenteritis digestive Both 0.06761 1.02 0.999,1.03 15492 155105 0.1349 1.01 0.996,1.03 15242 154183
559 Ileostomy status digestive Both 0.2489 1.03 0.979,1.08 1656 16541 0.317 1.03 0.975,1.08 1609 16417
560 Intestinal obstruction without mention of hernia digestive Both 0.673 1.01 0.975,1.04 3936 39337 0.6081 0.991 0.956,1.03 3273 33322
560.1 Paralytic ileus digestive Both 0.7534 1.01 0.927,1.11 523 5231 0.873 1.01 0.92,1.1 515 5205
560.2 Impaction of intestine digestive Both 0.1455 1.09 0.969,1.24 268 2671 0.1762 1.09 0.962,1.23 262 2650
560.3 Peritoneal or intestinal adhesions digestive Both 0.3097 1.04 0.966,1.11 832 8317 0.4188 1.03 0.959,1.11 816 8265
560.4 Other intestinal obstruction digestive Both 0.7261 0.994 0.959,1.03 3358 33550 0.6081 0.991 0.956,1.03 3273 33322
561 Symptoms involving digestive system digestive Both 0.3524 1.01 0.991,1.02 15772 157686 0.4786 1.02 0.969,1.07 1670 16756
561.1 Diarrhea digestive Both 0.04677 1.1 1.0,1.21 466 4653 0.06918 1.09 0.993,1.2 456 4619
561.2 Flatulence digestive Both 0.4446 1.02 0.97,1.07 1687 16859 0.4786 1.02 0.969,1.07 1670 16756
562 Diverticulosis and diverticulitis digestive Both 0.2188 1.01 0.995,1.02 26714 211692 0.2818 1.01 0.994,1.02 26331 210296
562.1 Diverticulosis digestive Both 0.227 1.01 0.995,1.02 26672 211642 0.2818 1.01 0.994,1.02 26331 210296
563 Constipation digestive Both 0.6855 1.0 0.984,1.02 10314 103140 0.8375 0.998 0.977,1.02 9960 102482
564 Functional digestive disorders digestive Both 0.5224 0.995 0.982,1.01 21639 209949 0.9908 1.0 0.983,1.02 14936 150622
564.1 Irritable Bowel Syndrome digestive Both 0.1618 0.98 0.953,1.01 5508 55117 0.1202 0.978 0.951,1.01 5459 54829
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.09333 1.04 0.993,1.1 1645 16457 0.0955 1.04 0.992,1.1 1602 16344
564.9 Personal history of diseases of digestive system digestive Both 0.912 1.0 0.984,1.02 15186 151648 0.9908 1.0 0.983,1.02 14936 150622
565 Anal and rectal conditions digestive Both 0.0123 1.02 1.0,1.04 14744 147535 0.02951 1.03 1.0,1.05 7251 72894
565.1 Anal and rectal polyp digestive Both 0.04467 1.02 1.0,1.05 7351 73533 0.02951 1.03 1.0,1.05 7251 72894
567 Peritonitis and retroperitoneal infections digestive Both 0.9333 0.997 0.932,1.07 929 9293 0.618 0.983 0.918,1.05 903 9214
568 Other disorders of peritoneum digestive Both 0.6081 1.01 0.974,1.05 3262 32602 0.4102 1.02 0.979,1.05 3056 30757
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.4305 1.01 0.978,1.05 3101 30987 0.4102 1.02 0.979,1.05 3056 30757
569 Other disorders of intestine digestive Both 0.0912 1.03 0.996,1.06 4192 41922 0.4764 1.04 0.941,1.14 475 4829
569.1 Toxic gastroenteritis and colitis digestive Both 0.7925 1.02 0.862,1.22 148 1479 0.9376 1.01 0.843,1.2 137 1462
569.2 Gastrointestinal complications digestive Both 0.492 1.03 0.941,1.14 486 4868 0.4764 1.04 0.941,1.14 475 4829
571 Chronic liver disease and cirrhosis digestive Both 0.1005 1.03 0.994,1.07 2957 29628 0.3828 1.04 0.951,1.14 519 5235
571.5 Other chronic nonalcoholic liver disease digestive Both 0.4446 1.02 0.97,1.07 1689 16917 0.3396 0.911 0.754,1.1 112 1129
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.3342 0.911 0.753,1.1 113 1139 0.3396 0.911 0.754,1.1 112 1129
571.6 Primary biliary cirrhosis digestive Both 0.6839 0.973 0.855,1.11 257 2568 0.9016 0.992 0.87,1.13 253 2546
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.2018 1.04 0.977,1.11 976 9804 0.3828 1.04 0.951,1.14 519 5235
571.81 Portal hypertension digestive Both 0.5 1.03 0.942,1.13 528 5285 0.3828 1.04 0.951,1.14 519 5235
572 Ascites (non malignant) digestive Both 0.5 1.02 0.966,1.07 1544 15454 0.6324 1.01 0.961,1.07 1495 15330
573 Other disorders of liver digestive Both 0.7691 1.01 0.956,1.06 1496 14982 0.5689 0.96 0.834,1.1 204 2070
573.2 Liver replaced by transplant digestive Both 0.1125 1.18 0.961,1.46 96 960 0.1466 1.17 0.947,1.44 94 953
573.3 Hepatomegaly digestive Both 0.6383 1.03 0.912,1.16 297 2968 0.7129 1.02 0.905,1.16 285 2942
573.5 Jaundice (not of newborn) digestive Both 0.0257 1.08 1.01,1.16 896 8955 0.05012 1.07 1.0,1.15 867 8882
573.7 Abnormal results of function study of liver digestive Both 0.6607 1.01 0.973,1.04 3454 34597 0.7328 1.01 0.971,1.04 3367 34334
573.9 Abnormal serum enzyme levels digestive Both 0.5395 0.957 0.833,1.1 209 2089 0.5689 0.96 0.834,1.1 204 2070
574 Cholelithiasis and cholecystitis digestive Both 0.002818 1.03 1.01,1.04 15607 156123 0.7178 1.01 0.968,1.05 2710 27276
574.1 Cholelithiasis digestive Both 7.244E-4 1.03 1.01,1.05 13549 135537 0.1057 1.02 0.995,1.05 5387 53909
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.03548 1.06 1.0,1.12 1506 15072 0.06166 1.05 0.998,1.11 1489 14941
574.12 Cholelithiasis with other cholecystitis digestive Both 0.1021 1.02 0.995,1.05 5429 54289 0.1057 1.02 0.995,1.05 5387 53909
574.2 Calculus of bile duct digestive Both 0.302 1.02 0.981,1.06 2620 26191 0.2588 1.02 0.983,1.07 2584 25986
574.3 Cholecystitis without cholelithiasis digestive Both 0.7079 1.01 0.969,1.05 2748 27523 0.7178 1.01 0.968,1.05 2710 27276
575 Other biliary tract disease digestive Both 0.2018 1.02 0.989,1.06 3867 38724 0.8356 1.01 0.904,1.13 325 3461
575.1 Cholangitis digestive Both 0.02042 1.11 1.02,1.22 495 4945 0.0195 1.12 1.02,1.22 486 4897
575.2 Obstruction of bile duct digestive Both 0.1714 1.05 0.978,1.13 774 7756 0.2218 1.05 0.972,1.13 758 7705
575.6 Cholesterolosis of gallbladder digestive Both 0.4797 1.04 0.941,1.14 458 4577 0.5272 1.03 0.937,1.14 454 4542
575.7 Other disorders of gallbladder digestive Both 0.955 0.998 0.945,1.05 1408 14107 0.9162 1.0 0.949,1.06 1391 14005
575.8 Other disorders of biliary tract digestive Both 0.9886 1.0 0.938,1.07 1036 10367 0.873 0.995 0.933,1.06 1018 10282
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.673 1.02 0.918,1.14 348 3488 0.8356 1.01 0.904,1.13 325 3461
577 Diseases of pancreas digestive Both 0.3758 1.02 0.978,1.06 2668 26677 0.6792 1.02 0.919,1.14 354 3611
577.1 Acute pancreatitis digestive Both 0.4477 1.02 0.972,1.07 1996 19962 0.4477 1.02 0.972,1.07 1967 19792
577.2 Chronic pancreatitis digestive Both 0.4875 1.03 0.944,1.13 515 5149 0.4831 1.03 0.943,1.13 503 5096
577.3 Cyst and pseudocyst of pancreas digestive Both 0.6281 1.03 0.923,1.14 365 3650 0.6792 1.02 0.919,1.14 354 3611
578 Gastrointestinal hemorrhage digestive Both 0.3524 0.993 0.979,1.01 20626 206278 0.6546 1.01 0.978,1.04 5201 52388
578.1 Hematemesis digestive Both 0.6561 0.989 0.944,1.04 1958 19564 0.561 0.986 0.941,1.03 1893 19405
578.2 Blood in stool digestive Both 0.857 1.0 0.964,1.05 2626 26283 0.6427 1.01 0.969,1.05 2576 26033
578.8 Hemorrhage of rectum and anus digestive Both 0.1995 0.988 0.971,1.01 13073 130745 0.2023 0.988 0.971,1.01 12941 129803
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.5534 1.01 0.98,1.04 5275 52787 0.6546 1.01 0.978,1.04 5201 52388
579 Other symptoms involving abdomen and pelvis digestive Both 0.2564 1.03 0.978,1.09 1548 15498 0.9661 0.999 0.949,1.05 1635 16416
579.2 Splenomegaly digestive Both 0.3597 1.05 0.948,1.16 422 4246 0.4677 1.04 0.939,1.15 416 4214
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.8974 0.997 0.948,1.05 1654 16540 0.9661 0.999 0.949,1.05 1635 16416
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.3573 1.02 0.973,1.08 1531 15350 0.5284 1.04 0.918,1.18 241 2511
580.1 Glomerulonephritis genitourinary Both 0.863 1.01 0.944,1.07 1052 10544 0.4325 0.972 0.906,1.04 855 8672
580.11 Proliferative glomerulonephritis genitourinary Both 0.7145 0.957 0.756,1.21 74 738 0.6138 0.94 0.739,1.2 71 729
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.001349 1.33 1.12,1.58 135 1360 0.00182 1.32 1.11,1.57 132 1345
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.3855 0.97 0.905,1.04 876 8769 0.4325 0.972 0.906,1.04 855 8672
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.01738 1.12 1.02,1.23 468 4697 0.02884 1.11 1.01,1.22 456 4652
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.3631 1.06 0.935,1.2 246 2460 0.5284 1.04 0.918,1.18 241 2511
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.3864 1.06 0.934,1.19 253 2529 0.5284 1.04 0.918,1.18 241 2511
585 Renal failure genitourinary Both 0.01514 1.03 1.01,1.06 6967 69751 0.7727 1.01 0.923,1.11 486 4923
585.1 Acute renal failure genitourinary Both 0.02455 1.04 1.0,1.07 4527 45305 0.0537 1.03 0.999,1.06 4313 44837
585.2 Renal failure NOS genitourinary Both 0.1099 1.04 0.99,1.1 1460 14625 0.1914 1.04 0.982,1.09 1412 14485
585.3 Chronic renal failure [CKD] genitourinary Both 0.2 1.03 0.986,1.07 2644 26484 0.7727 1.01 0.923,1.11 486 4923
585.31 Renal dialysis genitourinary Both 0.8531 1.01 0.92,1.11 496 4955 0.7727 1.01 0.923,1.11 486 4923
586 Other disorders of the kidney and ureters genitourinary Both 0.05495 1.04 0.999,1.07 3355 33580 0.1164 1.06 0.986,1.13 895 9063
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.9016 0.991 0.859,1.14 208 2089 0.6808 0.968 0.829,1.13 174 1780
586.11 Small kidney genitourinary Both 0.6855 0.969 0.832,1.13 179 1799 0.6808 0.968 0.829,1.13 174 1780
586.2 Cyst of kidney, acquired genitourinary Both 0.1035 1.05 0.99,1.11 1257 12582 0.07244 1.05 0.995,1.12 1224 12459
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.3828 0.899 0.708,1.14 80 799 0.4102 0.903 0.708,1.15 77 789
586.4 Stricture/obstruction of ureter genitourinary Both 0.1172 1.06 0.986,1.13 910 9122 0.1164 1.06 0.986,1.13 895 9063
587 Kidney replaced by transpant genitourinary Both 0.1618 0.927 0.834,1.03 368 3683 0.1959 0.932 0.839,1.04 365 3660
588 Disorders resulting from impaired renal function genitourinary Both 0.6266 1.05 0.858,1.29 99 990 0.6194 1.05 0.859,1.29 99 982
589 Abnormal results of function study of kidney genitourinary Both 0.4764 1.07 0.886,1.3 116 1158 0.547 1.06 0.876,1.28 113 1147
590 Pyelonephritis genitourinary Both 0.08318 1.05 0.994,1.11 1328 13285 0.1194 1.05 0.988,1.11 1310 13201
591 Urinary tract infection genitourinary Both 0.4977 1.01 0.988,1.03 12400 123937 0.7745 1.0 0.984,1.02 12102 122965
592 Cystitis and urethritis genitourinary Both 0.4887 1.01 0.976,1.05 2966 29661 0.07762 0.869 0.743,1.02 163 1653
592.1 Cystitis genitourinary Both 0.2028 1.03 0.987,1.07 2904 29035 0.3105 0.935 0.822,1.06 248 2474
592.11 Acute cystitis genitourinary Both 0.1274 1.14 0.962,1.36 138 1372 0.1614 1.13 0.952,1.35 137 1364
592.12 Chronic cystitis genitourinary Both 0.3184 1.04 0.967,1.11 889 8890 0.3192 1.04 0.966,1.11 881 8816
592.13 Chronic interstitial cystitis genitourinary Both 0.2339 0.925 0.813,1.05 249 2486 0.3105 0.935 0.822,1.06 248 2474
592.2 Urethritis and urethral syndrome genitourinary Both 0.1432 0.891 0.762,1.04 165 1662 0.07762 0.869 0.743,1.02 163 1653
593 Hematuria genitourinary Both 0.9183 0.999 0.983,1.02 16068 160204 0.865 0.999 0.982,1.02 15887 158856
594 Urinary calculus genitourinary Both 0.8414 1.0 0.977,1.03 6376 63761 0.4808 0.984 0.94,1.03 2036 20359
594.1 Calculus of kidney genitourinary Both 0.342 1.02 0.981,1.06 3175 31757 0.3126 1.02 0.982,1.06 3132 31478
594.2 Calculus of lower urinary tract genitourinary Both 0.9354 1.0 0.932,1.08 776 7764 0.8933 1.0 0.934,1.08 767 7676
594.3 Calculus of ureter genitourinary Both 0.2679 0.977 0.936,1.02 2401 24024 0.2864 0.977 0.937,1.02 2379 23815
594.8 Renal colic genitourinary Both 0.4753 0.984 0.94,1.03 2050 20500 0.4808 0.984 0.94,1.03 2036 20359
595 Hydronephrosis genitourinary Both 0.02399 1.06 1.01,1.11 1936 19395 0.06457 1.05 0.997,1.1 1902 19230
596 Other disorders of bladder genitourinary Both 0.4699 1.01 0.987,1.03 9771 97778 0.8472 1.0 0.955,1.06 1634 16427
596.1 Bladder neck obstruction genitourinary Both 0.7244 1.01 0.963,1.06 1969 19690 0.857 1.0 0.958,1.05 1929 19449
596.5 Functional disorders of bladder genitourinary Both 0.6081 1.01 0.963,1.07 1658 16572 0.8472 1.0 0.955,1.06 1634 16427
597 Other disorders of urethra and urinary tract genitourinary Both 0.02455 1.04 1.0,1.07 3913 39135 0.9484 0.993 0.799,1.23 75 771
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.003162 1.06 1.02,1.09 3317 33137 0.003467 1.05 1.02,1.09 3289 32823
597.2 Urinary complications NEC genitourinary Both 0.9683 1.0 0.812,1.24 78 778 0.9484 0.993 0.799,1.23 75 771
598 Abnormal findings on examination of urine genitourinary Both 0.309 0.982 0.949,1.02 3528 35302 0.166 0.919 0.816,1.04 299 2994
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.191 0.924 0.821,1.04 304 3035 0.166 0.919 0.816,1.04 299 2994
599 Other symptoms/disorders or the urinary system genitourinary Both 0.1138 0.988 0.973,1.0 18428 184311 0.8318 0.995 0.949,1.04 1891 18980
599.1 Urinary obstruction genitourinary Both 0.1652 1.12 0.955,1.31 166 1670 0.2118 1.11 0.944,1.29 163 1659
599.2 Retention of urine genitourinary Both 0.009772 1.03 1.01,1.06 6718 67168 0.02884 1.03 1.0,1.06 6546 66443
599.3 Dysuria genitourinary Both 0.5117 1.02 0.962,1.08 1196 11967 0.7834 1.01 0.95,1.07 1173 11870
599.4 Urinary incontinence genitourinary Both 0.1409 0.984 0.962,1.01 8748 87477 0.08511 0.981 0.959,1.0 8658 86892
599.5 Frequency of urination and polyuria genitourinary Both 0.1459 0.976 0.945,1.01 4018 40144 0.1072 0.974 0.942,1.01 3965 39840
599.6 Oliguria and anuria genitourinary Both 0.6427 0.954 0.78,1.17 105 1059 0.5585 0.941 0.767,1.15 101 1049
599.8 Other symptoms involving urinary system genitourinary Both 0.4335 0.903 0.7,1.17 62 620 0.4256 0.902 0.699,1.16 62 615
599.9 Other abnormality of urination genitourinary Both 0.8147 0.994 0.949,1.04 1913 19151 0.8318 0.995 0.949,1.04 1891 18980
600 Hyperplasia of prostate genitourinary Male 0.1493 1.01 0.995,1.03 11093 87892 0.2259 1.01 0.992,1.03 10904 86937
601 Inflammatory diseases of prostate genitourinary Male 0.3741 1.02 0.976,1.07 2081 20818 0.6368 1.03 0.913,1.16 302 2993
601.1 Prostatitis genitourinary Male 0.3141 1.03 0.975,1.08 1563 15644 0.8337 1.01 0.941,1.08 897 8982
601.11 Acute prostatitis genitourinary Male 0.2223 0.919 0.803,1.05 234 2358 0.1637 0.907 0.791,1.04 229 2339
601.12 Chronic prostatitis genitourinary Male 0.8035 1.01 0.943,1.08 910 9089 0.8337 1.01 0.941,1.08 897 8982
601.3 Orchitis and epididymitis genitourinary Male 0.5754 0.924 0.702,1.22 59 588 0.6026 0.929 0.703,1.23 57 582
601.4 Balanoposthitis genitourinary Male 0.811 0.985 0.873,1.11 287 2864 0.8054 0.985 0.872,1.11 285 2841
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.6067 1.03 0.915,1.16 303 3019 0.6368 1.03 0.913,1.16 302 2993
602 Other disorders of prostate genitourinary Male 0.4487 1.02 0.966,1.08 1341 13408 0.4315 1.02 0.967,1.08 1328 13228
603 Other disorders of testis genitourinary Male 0.6776 1.01 0.966,1.06 2150 21512 0.3184 1.03 0.973,1.09 1316 13271
603.1 Hydrocele genitourinary Male 0.4446 1.02 0.966,1.08 1339 13402 0.3184 1.03 0.973,1.09 1316 13271
604 Disorders of penis genitourinary Male 0.9977 1.0 0.965,1.04 3280 32779 0.9354 0.998 0.96,1.04 2693 26954
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.8913 0.997 0.959,1.04 2719 27172 0.9354 0.998 0.96,1.04 2693 26954
605 Erectile dysfunction [ED] genitourinary Male 0.6918 0.975 0.862,1.1 278 2800 0.6427 0.971 0.857,1.1 273 2774
608 Other disorders of male genital organs genitourinary Male 0.3767 1.02 0.979,1.06 2822 28236 0.3573 1.02 0.98,1.06 2784 27983
609 Male infertility and abnormal spermatozoa genitourinary Male 0.415 1.06 0.922,1.22 214 2138 0.8933 1.01 0.861,1.19 164 1671
609.1 Infertility, male genitourinary Male 0.1469 1.21 0.935,1.57 63 638 0.1479 1.21 0.935,1.56 63 636
609.2 Abnormal spermatozoa genitourinary Male 0.9931 0.999 0.853,1.17 169 1698 0.8933 1.01 0.861,1.19 164 1671
610 Benign mammary dysplasias genitourinary Female 0.3076 0.979 0.939,1.02 2482 24809 0.03981 0.92 0.85,0.996 694 6923
610.1 Cystic mastopathy genitourinary Female 0.9616 0.998 0.933,1.07 925 9250 0.9977 1.0 0.934,1.07 920 9199
610.2 Fibroadenosis of breast genitourinary Female 0.3162 0.94 0.833,1.06 306 3057 0.3199 0.94 0.833,1.06 303 3046
610.3 Fibrosclerosis of breast genitourinary Female 0.4786 0.958 0.849,1.08 302 3018 0.4864 0.958 0.85,1.08 301 2993
610.4 Benign neoplasm of breast genitourinary Female 0.3404 0.974 0.922,1.03 1388 13865 0.2838 0.97 0.918,1.03 1377 13802
610.8 Other specified benign mammary dysplasias genitourinary Female 0.04677 0.923 0.852,0.999 696 6954 0.03981 0.92 0.85,0.996 694 6923
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.3882 1.02 0.972,1.08 1574 15731 0.3899 1.02 0.971,1.08 1501 15127
611.1 Abnormal mammogram genitourinary Both 0.7925 0.966 0.743,1.25 57 569 0.8035 0.967 0.745,1.26 57 568
611.3 Lump or mass in breast genitourinary Both 0.3289 1.03 0.974,1.08 1522 15213 0.3899 1.02 0.971,1.08 1501 15127
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.3273 0.966 0.902,1.04 887 8871 0.5808 0.98 0.913,1.05 847 8459
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.5649 0.98 0.913,1.05 849 8490 0.5808 0.98 0.913,1.05 847 8459
612.3 Congenital anomalies of breast genitourinary Both 0.2897 0.877 0.687,1.12 72 719 ,
613 Other nonmalignant breast conditions genitourinary Both 0.008318 0.933 0.887,0.982 1651 16519 0.2858 0.924 0.799,1.07 207 2056
613.1 Inflammatory disease of breast genitourinary Both 0.3105 0.961 0.889,1.04 720 7210 0.3475 0.963 0.891,1.04 715 7173
613.5 Mastodynia genitourinary Both 0.1306 0.838 0.667,1.05 77 768 0.1419 0.842 0.669,1.06 76 762
613.7 Other signs and symptoms in breast genitourinary Both 0.4721 0.972 0.899,1.05 702 7013 0.3837 0.966 0.893,1.04 692 6968
613.8 Other specified disorders of breast genitourinary Both 0.4276 0.954 0.85,1.07 327 3278 0.4436 0.956 0.851,1.07 325 3260
613.9 Breast disorder NOS genitourinary Both 0.2767 0.923 0.798,1.07 207 2069 0.2858 0.924 0.799,1.07 207 2056
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.4426 1.01 0.984,1.04 5711 57118 0.2075 1.08 0.956,1.23 270 2718
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.1253 1.03 0.991,1.08 2538 25363 0.1 1.03 0.993,1.08 2527 25254
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.2455 1.04 0.971,1.12 830 8308 0.3811 1.05 0.941,1.17 349 3498
614.31 Acute inflammatory pelvic disease genitourinary Female 0.2153 1.17 0.911,1.52 61 608 0.2158 1.17 0.911,1.51 61 606
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.5781 1.03 0.931,1.14 422 4221 0.5458 1.03 0.933,1.14 419 4206
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.3733 1.05 0.942,1.17 351 3510 0.3811 1.05 0.941,1.17 349 3498
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.8279 1.01 0.896,1.15 277 2775 0.8166 1.01 0.897,1.15 277 2763
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.9594 1.0 0.962,1.04 2601 26023 0.2075 1.08 0.956,1.23 270 2718
614.51 Cervicitis and endocervicitis genitourinary Female 0.1358 1.04 0.987,1.1 1318 13189 0.1442 1.04 0.986,1.1 1311 13126
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.8054 1.01 0.917,1.12 428 4273 0.7568 1.02 0.92,1.12 421 4246
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.4355 0.971 0.901,1.05 755 7574 0.4083 0.969 0.899,1.04 748 7544
614.54 Abscess or ulceration of vulva genitourinary Female 0.2938 1.07 0.944,1.21 274 2737 0.2075 1.08 0.956,1.23 270 2718
615 Endometriosis genitourinary Female 0.04266 1.03 1.0,1.07 4029 40284 0.02884 1.04 1.0,1.07 4012 40128
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.8531 0.989 0.881,1.11 304 3037 0.8851 0.991 0.882,1.11 301 3017
618 Genital prolapse genitourinary Female 0.1429 0.986 0.967,1.0 11689 116878 0.8831 0.994 0.918,1.08 677 6748
618.1 Prolapse of vaginal walls genitourinary Female 0.3334 0.988 0.965,1.01 7392 73940 0.3412 0.988 0.965,1.01 7351 73445
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.2339 0.983 0.956,1.01 5393 53918 0.2244 0.983 0.955,1.01 5368 53575
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.2056 1.06 0.968,1.16 512 5125 0.2118 1.06 0.967,1.16 510 5092
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.826 0.991 0.916,1.07 680 6794 0.8831 0.994 0.918,1.08 677 6748
619 Noninflammatory female genital disorders genitourinary Female 0.9954 1.0 0.978,1.02 8726 87297 0.8091 0.993 0.938,1.05 1341 13422
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.7516 0.988 0.914,1.07 729 7284 0.6902 0.984 0.911,1.06 724 7254
619.2 Disorders of uterus, NEC genitourinary Female 0.9954 1.0 0.965,1.04 3324 33273 0.975 0.999 0.964,1.04 3303 33099
619.3 Noninflammatory disorders of cervix genitourinary Female 0.5715 1.01 0.973,1.05 2860 28608 0.6412 1.01 0.971,1.05 2841 28468
619.4 Noninflammatory disorders of vagina genitourinary Female 0.8453 1.0 0.957,1.06 1768 17669 0.9594 1.0 0.953,1.05 1755 17575
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.8072 0.993 0.939,1.05 1350 13489 0.8091 0.993 0.938,1.05 1341 13422
620 Dysplasia of female genital organs genitourinary Female 0.5358 1.08 0.842,1.39 72 720 0.4887 1.09 0.849,1.41 70 715
621 Endometrial hyperplasia genitourinary Female 0.6668 1.01 0.954,1.08 1129 11294 0.6839 1.01 0.953,1.08 1122 11235
622 Polyp of female genital organs genitourinary Female 0.3311 0.99 0.97,1.01 10480 104803 0.4592 0.987 0.953,1.02 3418 34185
622.1 Polyp of corpus uteri genitourinary Female 0.3614 0.989 0.966,1.01 7857 78601 0.3864 0.99 0.967,1.01 7814 78171
622.2 Mucous polyp of cervix genitourinary Female 0.4571 0.987 0.953,1.02 3442 34387 0.4592 0.987 0.953,1.02 3418 34185
623 Hypertrophy of female genital organs genitourinary Female 0.3041 0.97 0.915,1.03 1268 12684 0.3475 0.972 0.917,1.03 1262 12619
624 Symptoms involving female genital tract genitourinary Female 0.7447 0.988 0.92,1.06 797 7961 0.02512 0.969 0.944,0.996 5822 58282
624.1 Dystrophy of female genital tract genitourinary Female 0.04677 0.872 0.762,0.998 237 2365 0.0389 0.867 0.757,0.993 235 2341
624.2 Atrophy of female genital tract genitourinary Female 0.7211 1.02 0.925,1.12 440 4398 0.6982 1.02 0.926,1.12 439 4367
624.9 stress incontinence, female genitourinary Female 0.0309 0.971 0.945,0.997 5865 58634 0.02512 0.969 0.944,0.996 5822 58282
625 Pain and other symptoms associated with female genital organs genitourinary Female 5.623E-4 1.07 1.03,1.11 2876 28740 0.2979 1.03 0.972,1.1 1187 11848
625.1 Dyspareunia genitourinary Female 0.3006 1.03 0.972,1.1 1188 11891 0.2979 1.03 0.972,1.1 1187 11848
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.1578 1.01 0.995,1.03 16168 115018 0.4446 0.978 0.925,1.03 1360 13581
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.07586 1.02 0.998,1.03 14110 109918 0.9419 0.999 0.966,1.03 3786 37890
626.11 Absent or infrequent menstruation genitourinary Female 0.2748 0.896 0.737,1.09 109 1099 0.2773 0.896 0.736,1.09 108 1091
626.12 Excessive or frequent menstruation genitourinary Female 0.01023 1.03 1.01,1.05 9727 91749 0.009333 1.03 1.01,1.05 9684 91405
626.13 Irregular menstrual cycle genitourinary Female 0.865 0.996 0.951,1.04 1985 19829 0.861 0.996 0.951,1.04 1975 19713
626.14 Irregular menstrual bleeding genitourinary Female 0.8892 0.998 0.965,1.03 3804 38021 0.9419 0.999 0.966,1.03 3786 37890
626.2 Dysmenorrhea genitourinary Female 0.1074 1.04 0.991,1.09 1778 17767 0.08913 1.04 0.994,1.1 1772 17692
626.4 Premenstrual tension syndromes genitourinary Female 0.2443 0.905 0.765,1.07 159 1587 0.2193 0.9 0.76,1.06 158 1578
626.8 Infertility, female genitourinary Female 0.4519 0.979 0.925,1.04 1362 13613 0.4446 0.978 0.925,1.03 1360 13581
627 Menopausal and postmenopausal disorders genitourinary Female 0.2254 0.988 0.968,1.01 10392 103948 0.2099 0.927 0.824,1.04 309 3078
627.1 Postmenopausal bleeding genitourinary Female 0.7925 0.997 0.976,1.02 9042 90439 0.8017 0.997 0.976,1.02 8979 89816
627.2 Symptomatic menopause genitourinary Female 0.5508 0.954 0.816,1.11 183 1826 0.6353 0.963 0.824,1.13 181 1813
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.2716 0.966 0.909,1.03 1111 11115 0.241 0.964 0.907,1.02 1104 11022
627.4 Premenopausal menorrhagia genitourinary Female 0.2042 0.926 0.823,1.04 310 3097 0.2099 0.927 0.824,1.04 309 3078
628 Ovarian cyst genitourinary Female 0.3491 1.01 0.985,1.05 4747 47482 0.3381 1.01 0.985,1.05 4718 47282
634 Miscarriage; stillbirth pregnancy complications Female 0.6081 0.992 0.964,1.02 5218 36422 0.8128 0.987 0.882,1.1 330 3298
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.1982 0.961 0.904,1.02 1136 11300 0.1991 0.961 0.904,1.02 1136 11284
634.3 Ectopic pregnancy pregnancy complications Female 0.7362 0.981 0.877,1.1 331 3305 0.8128 0.987 0.882,1.1 330 3298
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.2183 1.03 0.983,1.08 1974 17372 0.6053 1.02 0.958,1.08 1269 12297
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.1683 1.05 0.98,1.13 866 8614 0.1629 1.05 0.98,1.13 865 8603
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.6012 1.02 0.958,1.08 1270 12306 0.6053 1.02 0.958,1.08 1269 12297
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.9162 0.998 0.956,1.04 2347 19972 0.5957 1.02 0.956,1.08 1079 10749
636.2 Early onset of delivery pregnancy complications Female 0.879 0.994 0.914,1.08 617 6144 0.8831 0.994 0.914,1.08 617 6137
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.5715 1.02 0.957,1.08 1082 10766 0.5957 1.02 0.956,1.08 1079 10749
638 Other high-risk pregnancy pregnancy complications Female 0.6823 0.95 0.742,1.22 70 700 0.6792 0.949 0.741,1.22 70 698
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.6982 0.988 0.929,1.05 1110 11074 0.1862 0.924 0.822,1.04 307 3054
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.1824 0.923 0.821,1.04 307 3058 0.1862 0.924 0.822,1.04 307 3054
643 Excessive vomiting in pregnancy pregnancy complications Female 0.7762 1.02 0.885,1.18 215 2149 0.5559 1.05 0.888,1.25 153 1522
643.1 Hyperemesis gravidarum pregnancy complications Female 0.5508 1.05 0.889,1.25 153 1525 0.5559 1.05 0.888,1.25 153 1522
645 Late pregnancy and failed induction pregnancy complications Female 0.3443 1.03 0.97,1.09 1250 12450 0.3266 1.03 0.971,1.09 1249 12432
646 Other complications of pregnancy NEC pregnancy complications Female 0.2427 1.03 0.983,1.07 2228 20847 0.2317 1.03 0.983,1.07 2226 20816
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.4831 1.09 0.857,1.39 68 679 0.9661 1.0 0.884,1.14 275 2745
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.9705 1.0 0.884,1.14 275 2748 0.9661 1.0 0.884,1.14 275 2745
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.1146 0.85 0.695,1.04 113 1129 0.9397 1.01 0.867,1.17 193 1919
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.9397 1.01 0.867,1.17 193 1922 0.9397 1.01 0.867,1.17 193 1919
650 Normal delivery pregnancy complications Female 0.06918 0.957 0.913,1.0 1922 18973 0.06607 0.957 0.913,1.0 1919 18952
651 Multiple gestation pregnancy complications Female 2.399E-4 0.81 0.724,0.907 346 3454 2.455E-4 0.811 0.724,0.907 346 3451
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.9462 1.0 0.953,1.05 1716 16521 0.9419 1.0 0.953,1.05 1714 16503
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.9772 0.999 0.945,1.06 1401 13649 0.9931 1.0 0.946,1.06 1401 13629
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.618 0.943 0.747,1.19 74 739 0.618 0.943 0.747,1.19 74 739
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.695 1.01 0.974,1.04 4306 29454 0.6761 1.01 0.975,1.04 4302 29412
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.4217 0.922 0.757,1.12 109 1080 0.413 0.921 0.756,1.12 109 1078
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.1119 1.04 0.992,1.08 2265 18397 0.1072 1.04 0.992,1.08 2265 18369
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.7278 1.02 0.928,1.11 532 5316 0.7211 1.02 0.929,1.11 532 5310
665 Obstetrical/birth trauma pregnancy complications Female 0.8933 1.0 0.973,1.03 5313 29472 0.881 1.0 0.973,1.03 5308 29428
669 Complications of labor and delivery NEC pregnancy complications Female 0.9863 1.0 0.959,1.04 2552 21174 0.9954 1.0 0.959,1.04 2551 21143
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.6457 0.963 0.822,1.13 164 1628 0.6339 0.962 0.821,1.13 164 1626
674 Other complications of the puerperium NEC pregnancy complications Female 0.7962 0.983 0.866,1.12 262 2605 0.7962 0.983 0.866,1.12 262 2603
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.3614 0.89 0.692,1.14 63 624 0.3556 0.889 0.692,1.14 63 623
679 Complications of in utero procedures dermatologic Female 0.1963 1.2 0.909,1.59 53 530 0.1977 1.2 0.909,1.59 53 529
681 Superficial cellulitis and abscess dermatologic Both 0.6237 1.01 0.982,1.03 7200 72225 0.1592 0.941 0.864,1.02 584 5944
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.879 0.993 0.91,1.08 563 5647 0.9638 0.998 0.914,1.09 554 5605
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.6516 0.98 0.895,1.07 520 5208 0.7244 0.984 0.898,1.08 506 5175
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.3811 1.01 0.985,1.04 5481 55014 0.3155 1.01 0.986,1.04 5400 54539
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.3972 1.01 0.984,1.04 5487 55074 0.3155 1.01 0.986,1.04 5405 54607
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.3681 1.01 0.985,1.04 5444 54643 0.2958 1.02 0.987,1.04 5364 54177
681.7 Cellulitis and abscess of trunk dermatologic Both 0.195 0.946 0.87,1.03 597 5987 0.1592 0.941 0.864,1.02 584 5944
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.2588 1.03 0.976,1.09 1337 13427 0.3177 0.946 0.848,1.06 357 3600
686.1 Carbuncle and furuncle dermatologic Both 0.7413 0.993 0.951,1.04 2284 22925 0.7396 0.993 0.951,1.04 2246 22761
686.3 Pilonidal cyst dermatologic Both 0.7362 0.985 0.905,1.07 583 5837 0.6607 0.981 0.9,1.07 571 5809
686.4 Pyogenic granuloma dermatologic Both 0.3184 0.946 0.849,1.05 362 3615 0.3177 0.946 0.848,1.06 357 3600
687 Symptoms affecting skin dermatologic Both 0.08511 1.08 0.989,1.18 548 5508 0.867 0.997 0.959,1.04 2828 28675
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.4446 1.02 0.973,1.06 2146 21470 0.5395 1.01 0.97,1.06 2073 21296
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.08511 1.11 0.985,1.26 283 2839 0.08511 1.11 0.985,1.26 276 2823
687.3 Changes in skin texture dermatologic Both 0.8054 1.02 0.847,1.24 106 1070 0.798 1.03 0.848,1.24 105 1060
687.4 Disturbance of skin sensation dermatologic Both 0.7691 0.994 0.957,1.03 2884 28859 0.867 0.997 0.959,1.04 2828 28675
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.4477 1.01 0.983,1.04 5747 57521 0.3266 1.01 0.986,1.04 5694 57097
690 Erythematosquamous dermatosis dermatologic Both 0.9441 0.992 0.787,1.25 71 710 0.8375 0.971 0.737,1.28 53 527
690.1 Seborrheic dermatitis dermatologic Both 0.8128 0.967 0.734,1.28 53 530 0.8375 0.971 0.737,1.28 53 527
691 Congenital anomalies of skin dermatologic Both 0.9661 1.0 0.833,1.21 120 1199 0.9908 0.999 0.828,1.2 119 1192
694 Dyschromia and Vitiligo dermatologic Both 0.3357 0.968 0.907,1.03 986 9854 0.3864 1.09 0.896,1.33 116 1163
694.1 Vitiligo dermatologic Both 0.2234 1.17 0.907,1.52 60 599 0.1919 1.19 0.916,1.55 59 595
694.2 Other dyschromia dermatologic Both 0.09772 0.94 0.874,1.01 782 7821 0.104 0.941 0.875,1.01 779 7765
694.3 Vascular disorders of skin dermatologic Both 0.4217 1.08 0.891,1.32 117 1170 0.3864 1.09 0.896,1.33 116 1163
695 Erythematous conditions dermatologic Both 5.012E-4 1.08 1.03,1.12 2379 23813 0.8318 1.01 0.918,1.11 458 4646
695.1 Toxic erythema dermatologic Both 0.4159 1.08 0.892,1.32 109 1090 0.3999 1.09 0.894,1.32 109 1088
695.2 Bullous dermatoses dermatologic Both 0.0912 1.16 0.976,1.38 137 1365 0.9162 0.987 0.776,1.26 70 727
695.21 Dermatitis herpetiformis dermatologic Both 0.08318 1.27 0.969,1.66 57 569 0.0871 1.26 0.966,1.65 57 562
695.22 Pemphigus and pemphigoid dermatologic Both 0.7674 0.965 0.763,1.22 73 727 0.9162 0.987 0.776,1.26 70 727
695.3 Rosacea dermatologic Both 0.826 1.01 0.9,1.14 309 3097 0.9183 1.01 0.893,1.13 304 3067
695.4 Lupus (localized and systemic) dermatologic Both 6.607E-5 1.23 1.11,1.36 411 4114 5.248E-5 1.26 1.13,1.41 335 3383
695.41 Cutaneous lupus erythematosus dermatologic Both 0.3963 1.08 0.901,1.3 130 1295 0.4436 1.07 0.894,1.29 128 1292
695.42 Systemic lupus erythematosus dermatologic Both 9.55E-5 1.25 1.12,1.39 340 3407 5.248E-5 1.26 1.13,1.41 335 3383
695.7 Prurigo and Lichen dermatologic Both 0.02692 1.09 1.01,1.17 775 7760 0.02042 1.09 1.01,1.17 771 7692
695.8 Other specified erythematous conditions dermatologic Both 0.3681 1.06 0.932,1.21 236 2359 0.5082 1.08 0.859,1.36 76 754
695.81 Erythema nodosum dermatologic Both 0.52 1.08 0.858,1.35 76 760 0.5082 1.08 0.859,1.36 76 754
695.9 Unspecified erythematous condition dermatologic Both 0.7396 1.02 0.924,1.12 467 4672 0.8318 1.01 0.918,1.11 458 4646
696 Psoriasis and related disorders dermatologic Both 0.9484 1.0 0.959,1.05 2252 22509 0.7656 0.988 0.914,1.07 700 7002
696.4 Psoriasis dermatologic Both 0.8375 0.995 0.953,1.04 2198 21969 0.7656 0.988 0.914,1.07 700 7002
696.41 Psoriasis vulgaris dermatologic Both 0.7261 1.01 0.96,1.06 1680 16796 0.5848 1.01 0.964,1.07 1646 16643
696.42 Psoriatic arthropathy dermatologic Both 0.7345 0.987 0.913,1.07 706 7052 0.7656 0.988 0.914,1.07 700 7002
697 Sarcoidosis dermatologic Both 0.4436 1.04 0.947,1.13 539 5373 0.2972 1.05 0.959,1.15 531 5324
698 Pruritus and related conditions dermatologic Both 0.873 1.01 0.935,1.08 782 7814 0.873 1.01 0.934,1.08 774 7755
700 Corns and callosities dermatologic Both 0.08128 0.898 0.795,1.01 291 2904 0.05495 0.887 0.785,1.0 287 2885
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.4989 1.01 0.98,1.04 4663 46650 0.05888 1.21 0.992,1.48 101 1010
701.1 Keratoderma, acquired dermatologic Both 0.7311 0.961 0.768,1.2 87 870 0.5534 0.933 0.743,1.17 85 861
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.8995 0.997 0.956,1.04 2348 23478 0.7674 0.994 0.952,1.04 2317 23309
701.3 Circumscribed scleroderma dermatologic Both 0.6745 0.947 0.735,1.22 61 610 0.6823 0.948 0.736,1.22 61 599
701.4 Keloid scar dermatologic Both 0.7063 0.974 0.847,1.12 216 2159 0.5458 0.958 0.832,1.1 212 2149
701.5 Abnormal granulation tissue dermatologic Both 0.01 1.13 1.03,1.25 455 4568 0.01318 1.13 1.03,1.24 448 4543
701.6 Acquired acanthosis nigricans dermatologic Both 0.04571 1.22 1.0,1.49 102 1019 0.05888 1.21 0.992,1.48 101 1010
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.05129 0.973 0.946,1.0 5459 54587 0.1099 0.97 0.934,1.01 3039 30514
702.1 Actinic keratosis dermatologic Both 0.235 0.976 0.937,1.02 2585 25842 0.2275 0.975 0.937,1.02 2560 25598
702.2 Seborrheic keratosis dermatologic Both 0.1452 0.973 0.937,1.01 3078 30772 0.1099 0.97 0.934,1.01 3039 30514
703 Diseases of nail, NOS dermatologic Both 0.6561 0.976 0.875,1.09 354 3539 0.5662 1.02 0.954,1.09 954 9585
703.1 Ingrowing nail dermatologic Both 0.4887 1.02 0.959,1.09 966 9660 0.5662 1.02 0.954,1.09 954 9585
704 Diseases of hair and hair follicles dermatologic Both 0.06918 1.03 0.998,1.06 5267 52727 0.6776 0.951 0.749,1.21 75 755
704.1 Alopecia dermatologic Both 0.5943 1.05 0.875,1.26 125 1269 0.4406 1.08 0.894,1.29 122 1260
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.5943 0.938 0.74,1.19 76 759 0.6776 0.951 0.749,1.21 75 755
705 Disorders of sweat glands dermatologic Both 0.3069 1.07 0.938,1.22 228 2287 0.6808 0.982 0.902,1.07 573 5864
705.3 Hidradenitis dermatologic Both 0.3388 1.07 0.928,1.24 186 1868 0.3177 1.08 0.93,1.25 180 1857
705.8 Hyperhidrosis dermatologic Both 0.8054 0.99 0.91,1.08 591 5919 0.6808 0.982 0.902,1.07 573 5864
706 Diseases of sebaceous glands dermatologic Both 0.0871 1.02 0.997,1.04 8317 83195 0.07586 1.02 0.998,1.04 8702 87241
706.1 Acne dermatologic Both 0.3266 1.12 0.894,1.4 78 779 0.3006 1.13 0.899,1.41 78 774
706.2 Sebaceous cyst dermatologic Both 0.05888 1.02 0.999,1.04 8787 87882 0.07586 1.02 0.998,1.04 8702 87241
707 Chronic ulcer of skin dermatologic Both 0.0195 1.06 1.01,1.11 1953 19654 0.1343 1.06 0.983,1.13 832 8999
707.1 Decubitus ulcer dermatologic Both 0.02884 1.08 1.01,1.15 909 9097 0.1343 1.06 0.983,1.13 832 8999
709 Diffuse diseases of connective tissue dermatologic Both 0.02399 1.04 1.01,1.08 3432 34317 0.2606 1.02 0.983,1.06 2693 26928
709.2 Sicca syndrome dermatologic Both 0.001175 1.16 1.06,1.27 508 5073 0.001514 1.16 1.06,1.27 505 5041
709.3 Systemic sclerosis dermatologic Both 0.7762 0.978 0.837,1.14 176 1753 0.6918 0.969 0.828,1.13 172 1743
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.06607 0.787 0.61,1.02 65 649 0.05888 0.78 0.603,1.01 64 646
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.2218 1.02 0.985,1.07 2714 27144 0.2606 1.02 0.983,1.06 2693 26928
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.4864 0.984 0.941,1.03 2094 20961 0.3793 0.98 0.936,1.03 2051 20804
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.3758 1.04 0.956,1.13 602 6034 0.6871 1.02 0.921,1.13 392 3967
710.1 Osteomyelitis musculoskeletal Both 0.5176 1.03 0.944,1.12 556 5574 0.6871 1.02 0.921,1.13 392 3967
710.12 Chronic osteomyelitis musculoskeletal Both 0.4688 1.06 0.912,1.22 194 1947 0.4699 1.06 0.911,1.22 188 1938
710.19 Unspecified osteomyelitis musculoskeletal Both 0.7015 1.02 0.921,1.13 398 3997 0.6871 1.02 0.921,1.13 392 3967
711 Arthropathy associated with infections musculoskeletal Both 0.9036 0.994 0.898,1.1 421 4225 0.8414 1.01 0.902,1.13 325 3272
711.1 Pyogenic arthritis musculoskeletal Both 0.9506 1.0 0.895,1.12 328 3296 0.8414 1.01 0.902,1.13 325 3272
712 Infective connective tissue disorders musculoskeletal Both 0.1578 0.845 0.668,1.07 81 810 0.2421 0.869 0.687,1.1 80 806
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.7278 0.97 0.816,1.15 148 1499 0.4416 0.902 0.694,1.17 64 665
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.4335 0.902 0.696,1.17 65 669 0.4416 0.902 0.694,1.17 64 665
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.1718 0.98 0.951,1.01 4832 48320 0.1816 0.979 0.948,1.01 4293 43368
714.1 Rheumatoid arthritis musculoskeletal Both 0.1435 0.977 0.947,1.01 4372 43714 0.1816 0.979 0.948,1.01 4293 43368
715 Other inflammatory spondylopathies musculoskeletal Both 0.125 0.961 0.913,1.01 1659 16588 0.07943 0.928 0.854,1.01 614 6129
715.1 Sacroiliitis NEC musculoskeletal Both 0.7096 1.04 0.857,1.26 113 1129 0.7534 1.03 0.851,1.25 112 1127
715.2 Ankylosing spondylitis musculoskeletal Both 0.09333 0.932 0.858,1.01 618 6177 0.07943 0.928 0.854,1.01 614 6129
716 Other arthropathies musculoskeletal Both 0.399 1.0 0.994,1.02 37478 265375 0.4018 1.0 0.994,1.02 35521 260442
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.5164 1.01 0.977,1.05 3505 35090 0.547 1.01 0.976,1.05 3465 34777
716.2 Unspecified monoarthritis musculoskeletal Both 0.2118 1.01 0.994,1.03 15522 155339 0.1343 1.01 0.996,1.03 15405 154067
716.9 Arthropathy NOS musculoskeletal Both 0.3963 1.0 0.994,1.02 35944 262308 0.4018 1.0 0.994,1.02 35521 260442
717 Polymyalgia Rheumatica musculoskeletal Both 0.7096 0.989 0.93,1.05 1145 11480 0.7816 0.991 0.933,1.05 1131 11340
720 Spinal stenosis musculoskeletal Both 0.929 0.998 0.965,1.03 3705 37091 0.8892 0.998 0.964,1.03 3656 36767
721 Spondylosis and allied disorders musculoskeletal Both 0.6622 0.995 0.972,1.02 7832 78318 0.6607 0.975 0.872,1.09 339 3489
721.1 Spondylosis without myelopathy musculoskeletal Both 0.4436 0.989 0.96,1.02 5045 50451 0.4457 0.989 0.96,1.02 4972 50025
721.2 Spondylosis with myelopathy musculoskeletal Both 0.2735 1.09 0.936,1.26 189 1899 0.2754 1.09 0.936,1.26 188 1888
721.8 Other allied disorders of spine musculoskeletal Both 0.5521 0.967 0.866,1.08 352 3519 0.6607 0.975 0.872,1.09 339 3489
722 Intervertebral disc disorders musculoskeletal Both 0.9057 1.0 0.98,1.02 8978 89848 0.1611 1.02 0.991,1.05 4367 43806
722.1 Displacement of intervertebral disc musculoskeletal Both 0.8091 1.01 0.923,1.11 512 5116 0.873 1.01 0.919,1.1 503 5086
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.3266 0.981 0.943,1.02 2831 28328 0.4345 0.985 0.947,1.02 2788 28162
722.8 Postlaminectomy syndrome musculoskeletal Both 0.06918 0.788 0.609,1.02 67 669 0.04677 0.767 0.591,0.997 65 666
722.9 Other and unspecified disc disorder musculoskeletal Both 0.1538 1.02 0.992,1.06 4407 44127 0.1611 1.02 0.991,1.05 4367 43806
723 Other disorders of cervical region musculoskeletal Both 0.04074 1.1 1.0,1.2 517 5173 0.5433 0.941 0.773,1.15 106 1062
723.1 Torticollis musculoskeletal Both 0.5333 0.94 0.773,1.14 107 1068 0.5433 0.941 0.773,1.15 106 1062
724 Other and unspecified disorders of back musculoskeletal Both 0.1875 1.03 0.985,1.08 2052 20514 0.3083 1.03 0.976,1.08 1588 16021
724.1 Disorders of sacrum musculoskeletal Both 0.9141 1.01 0.909,1.11 403 4024 0.9141 1.01 0.909,1.11 402 4012
724.2 Disorders of coccyx musculoskeletal Both 0.9886 0.999 0.903,1.11 406 4054 0.9863 0.999 0.903,1.11 405 4042
724.8 Other symptoms referable to back musculoskeletal Both 0.02692 1.33 1.03,1.7 63 630 0.02512 1.34 1.04,1.73 61 626
724.9 Other unspecified back disorders musculoskeletal Both 0.263 1.03 0.978,1.08 1614 16139 0.3083 1.03 0.976,1.08 1588 16021
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.195 0.989 0.972,1.01 14663 146691 0.8072 0.991 0.924,1.06 846 8499
726.1 Enthesopathy musculoskeletal Both 0.542 0.993 0.973,1.01 9589 95900 0.6081 0.994 0.974,1.02 9505 95171
726.2 Synoviopathy musculoskeletal Both 0.2213 1.07 0.959,1.2 334 3336 0.2123 1.07 0.96,1.2 331 3324
726.3 Bursitis musculoskeletal Both 0.7063 0.987 0.92,1.06 854 8573 0.8072 0.991 0.924,1.06 846 8499
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.1377 0.982 0.958,1.01 7331 73332 0.811 0.979 0.821,1.17 143 1415
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.9594 0.999 0.96,1.04 2737 27406 0.8872 0.997 0.958,1.04 2714 27238
727.2 Bursitis disorders musculoskeletal Both 0.2148 1.13 0.93,1.38 103 1029 0.2158 1.13 0.929,1.38 102 1015
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.06166 0.965 0.93,1.0 3109 31085 0.05495 0.964 0.929,1.0 3086 30897
727.5 Rupture of synovium musculoskeletal Both 0.5902 0.977 0.897,1.06 586 5854 0.6081 0.978 0.898,1.07 581 5799
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.07586 1.11 0.99,1.24 353 3527 0.1096 1.1 0.98,1.23 349 3506
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.7727 0.974 0.817,1.16 143 1429 0.811 0.979 0.821,1.17 143 1415
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.0955 1.03 0.995,1.06 3677 36788 0.07943 1.03 0.996,1.07 3433 34411
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.2985 1.05 0.954,1.17 412 4115 0.3027 1.05 0.953,1.17 408 4099
728.7 Fasciitis musculoskeletal Both 0.3013 1.02 0.984,1.05 3803 38045 0.07943 1.03 0.996,1.07 3433 34411
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.06761 1.03 0.998,1.07 3477 34788 0.07943 1.03 0.996,1.07 3433 34411
729 Other disorders of soft tissues musculoskeletal Both 0.3631 1.01 0.986,1.04 6014 60309 0.4446 1.08 0.886,1.32 100 1001
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.4436 0.975 0.914,1.04 1005 10063 0.3758 0.971 0.91,1.04 993 10010
729.3 Panniculitis musculoskeletal Both 0.4688 1.08 0.882,1.31 101 1009 0.4446 1.08 0.886,1.32 100 1001
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.863 0.989 0.874,1.12 276 2758 0.8166 0.985 0.866,1.12 256 2597
731.1 Osteitis deformans [Paget's disease of bone] musculoskeletal Both 0.778 0.982 0.864,1.12 261 2609 0.8166 0.985 0.866,1.12 256 2597
732 Osteochondropathies musculoskeletal Both 0.1114 0.926 0.842,1.02 467 4679 0.879 0.98 0.757,1.27 57 565
732.1 Juvenile osteochondrosis musculoskeletal Both 0.1892 0.909 0.788,1.05 207 2068 0.1875 0.908 0.787,1.05 205 2061
732.7 Osteochondritis dissecans musculoskeletal Both 0.8241 0.971 0.75,1.26 57 570 0.879 0.98 0.757,1.27 57 565
733 Other disorders of bone and cartilage musculoskeletal Both 0.5861 0.987 0.94,1.04 1777 17814 0.673 1.04 0.861,1.26 119 1204
733.2 Cyst of bone musculoskeletal Both 0.5458 0.965 0.86,1.08 311 3115 0.5212 0.963 0.858,1.08 308 3097
733.4 Aseptic necrosis of bone musculoskeletal Both 0.07762 0.924 0.847,1.01 540 5393 0.1 0.928 0.85,1.01 528 5351
733.6 Costochondritis musculoskeletal Both 0.5808 0.949 0.79,1.14 128 1276 0.618 0.954 0.794,1.15 127 1261
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.1618 0.959 0.904,1.02 1231 12313 0.1449 0.957 0.902,1.02 1217 12234
733.9 Chondromalacia musculoskeletal Both 0.6823 1.04 0.861,1.26 121 1206 0.673 1.04 0.861,1.26 119 1204
735 Acquired foot deformities musculoskeletal Both 0.02884 0.977 0.956,0.998 9603 96090 0.09772 0.979 0.954,1.0 6609 66010
735.1 Flat foot musculoskeletal Both 0.3673 1.07 0.921,1.25 189 1910 0.4667 1.06 0.908,1.24 186 1894
735.2 Acquired toe deformities musculoskeletal Both 0.001862 0.955 0.928,0.983 5070 50712 0.3281 0.974 0.925,1.03 1548 15414
735.21 Hammer toe (acquired) musculoskeletal Both 0.06166 0.956 0.912,1.0 1929 19324 0.05623 0.955 0.911,1.0 1919 19171
735.23 Hallux rigidus musculoskeletal Both 0.3443 0.975 0.926,1.03 1555 15527 0.3281 0.974 0.925,1.03 1548 15414
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.07586 0.977 0.953,1.0 6643 66463 0.09772 0.979 0.954,1.0 6609 66010
736 Other acquired deformities of limbs musculoskeletal Both 0.6486 1.01 0.961,1.07 1627 16282 0.1026 1.12 0.978,1.28 243 2454
736.2 Acquired deformities of finger musculoskeletal Both 0.1396 1.1 0.968,1.26 248 2476 0.1026 1.12 0.978,1.28 243 2454
737 Curvature of spine musculoskeletal Both 0.3963 0.974 0.917,1.04 1128 11300 0.3548 0.971 0.911,1.03 1038 10527
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.4295 0.975 0.916,1.04 1061 10632 0.3548 0.971 0.911,1.03 1038 10527
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.3055 1.02 0.978,1.07 1904 19058 0.4246 1.02 0.969,1.08 1499 15018
738.4 Acquired spondylolisthesis musculoskeletal Both 0.4732 1.02 0.967,1.07 1513 15147 0.4246 1.02 0.969,1.08 1499 15018
739 Contracture of joint musculoskeletal Both 0.3076 0.953 0.868,1.05 488 4884 0.1919 0.939 0.855,1.03 483 4854
740 Osteoarthrosis musculoskeletal Both 0.4436 1.0 0.992,1.02 27707 231603 0.6516 1.0 0.986,1.02 12070 121692
740.1 Osteoarthritis; localized musculoskeletal Both 0.1309 1.01 0.996,1.03 17412 169419 0.9311 0.995 0.893,1.11 344 3451
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.1799 1.01 0.993,1.04 8974 89750 0.2056 1.01 0.992,1.04 8900 88891
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.8279 0.988 0.887,1.1 348 3474 0.9311 0.995 0.893,1.11 344 3451
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.2564 1.05 0.965,1.14 598 5969 0.4102 1.04 0.952,1.13 591 5919
740.9 Osteoarthrosis NOS musculoskeletal Both 0.5572 1.01 0.987,1.02 12270 122792 0.6516 1.0 0.986,1.02 12070 121692
741 Symptoms and disorders of the joints musculoskeletal Both 0.2576 1.02 0.986,1.06 3563 35648 0.05012 0.745 0.555,1.0 54 534
741.1 Ankylosis of joint musculoskeletal Both 0.4036 0.917 0.747,1.12 102 1019 0.4036 0.916 0.746,1.13 101 1006
741.2 Stiffness of joint musculoskeletal Both 0.04571 1.09 1.0,1.18 614 6146 0.06166 1.08 0.996,1.17 608 6110
741.3 Difficulty in walking musculoskeletal Both 0.6412 0.962 0.819,1.13 154 1540 0.8091 0.98 0.832,1.15 148 1528
741.4 Joint effusions musculoskeletal Both 0.6982 1.01 0.957,1.07 1418 14197 0.7112 1.01 0.957,1.07 1400 14066
741.5 Hemarthrosis musculoskeletal Both 0.2472 0.891 0.734,1.08 110 1100 0.2559 0.893 0.734,1.09 109 1087
741.6 Villonodular synovitis musculoskeletal Both 0.05012 0.744 0.554,1.0 54 535 0.05012 0.745 0.555,1.0 54 534
742 Derangement of joint, non-traumatic musculoskeletal Both 0.455 1.01 0.977,1.05 2843 28441 0.0955 1.04 0.993,1.09 1985 19827
742.1 Loose body in joint musculoskeletal Both 0.7551 1.02 0.91,1.14 333 3337 0.826 1.01 0.905,1.13 332 3314
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.5058 0.934 0.762,1.14 95 960 0.514 0.935 0.764,1.14 95 955
742.8 Articular cartilage disorder musculoskeletal Both 0.3532 0.957 0.872,1.05 500 4996 0.3467 0.956 0.872,1.05 499 4964
742.9 Other derangement of joint musculoskeletal Both 0.09772 1.04 0.993,1.09 1993 19926 0.0955 1.04 0.993,1.09 1985 19827
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.778 0.997 0.973,1.02 7563 75729 0.07244 0.935 0.87,1.01 802 8089
743.1 Osteoporosis musculoskeletal Both 0.4753 1.01 0.984,1.04 6400 64107 0.8147 0.989 0.903,1.08 507 5223
743.11 Osteoporosis NOS musculoskeletal Both 0.8166 1.0 0.976,1.03 5549 55604 0.826 1.0 0.976,1.03 5442 55151
743.13 Other specified osteoporosis musculoskeletal Both 0.8933 0.994 0.909,1.09 529 5283 0.8147 0.989 0.903,1.08 507 5223
743.2 Pathologic fracture musculoskeletal Both 0.2421 0.947 0.865,1.04 516 5179 0.399 0.961 0.876,1.05 492 5143
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.0631 0.934 0.869,1.0 815 8144 0.07244 0.935 0.87,1.01 802 8089
745 Pain in joint musculoskeletal Both 0.8072 1.0 0.98,1.03 7975 79789 0.877 1.0 0.979,1.03 7885 79192
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.7852 1.01 0.967,1.05 2802 28058 0.52 1.05 0.897,1.24 166 1672
747.1 Cardiac congenital anomalies congenital anomalies Both 0.7998 1.01 0.966,1.05 2628 26323 0.7129 1.01 0.961,1.06 1777 17980
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.3281 0.959 0.881,1.04 584 5838 0.2698 0.953 0.875,1.04 579 5803
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.597 1.04 0.905,1.19 235 2358 0.6012 1.04 0.905,1.19 235 2341
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.8337 1.01 0.958,1.05 1816 18200 0.7129 1.01 0.961,1.06 1777 17980
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.4581 1.06 0.904,1.25 167 1680 0.52 1.05 0.897,1.24 166 1672
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.2786 0.845 0.624,1.15 51 510 ,
749 Congenital anomalies of face and neck congenital anomalies Both 0.1245 0.91 0.807,1.03 303 3029 0.1303 0.911 0.808,1.03 302 3018
750 Digestive congenital anomalies congenital anomalies Both 0.5321 1.03 0.949,1.11 686 6870 0.7586 1.03 0.854,1.24 115 1170
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.3548 1.06 0.942,1.18 327 3263 0.8531 1.01 0.873,1.18 187 1891
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.9705 1.0 0.865,1.16 191 1909 0.8531 1.01 0.873,1.18 187 1891
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.8831 1.01 0.905,1.12 356 3574 0.7586 1.03 0.854,1.24 115 1170
750.21 Congenital anomalies of intestine congenital anomalies Both 0.6745 0.972 0.849,1.11 225 2256 0.6252 0.967 0.844,1.11 222 2240
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.7228 1.03 0.859,1.25 117 1179 0.7586 1.03 0.854,1.24 115 1170
751 Genitourinary congenital anomalies congenital anomalies Both 0.4613 0.98 0.93,1.03 1527 15286 0.4742 0.959 0.855,1.08 325 3322
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.631 1.02 0.943,1.1 694 6932 0.8414 1.01 0.883,1.16 220 2197
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.6109 1.03 0.932,1.13 455 4546 0.5636 1.03 0.935,1.13 453 4527
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.8492 1.01 0.883,1.16 222 2217 0.8414 1.01 0.883,1.16 220 2197
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.5662 0.979 0.912,1.05 836 8385 0.4742 0.959 0.855,1.08 325 3322
751.21 Cystic kidney disease congenital anomalies Both 0.4909 0.965 0.873,1.07 424 4246 0.5321 0.968 0.874,1.07 416 4202
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.5212 0.964 0.861,1.08 333 3346 0.4742 0.959 0.855,1.08 325 3322
752 Nervous system congenital anomalies congenital anomalies Both 0.8995 0.993 0.888,1.11 328 3307 0.5188 1.08 0.857,1.36 78 778
752.1 Neural tube defects congenital anomalies Both 0.6776 0.973 0.857,1.11 253 2557 0.6397 1.03 0.899,1.19 207 2101
752.11 Spina bifida congenital anomalies Both 0.5957 1.04 0.903,1.19 208 2108 0.6397 1.03 0.899,1.19 207 2101
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.5129 1.08 0.858,1.36 78 780 0.5188 1.08 0.857,1.36 78 778
753 Congenital anomalies of the eye congenital anomalies Both 0.1114 0.866 0.725,1.03 127 1270 0.3162 0.888 0.703,1.12 76 754
753.1 Congenital cataract and lens anomalies congenital anomalies Both 0.3083 0.886 0.702,1.12 76 760 0.3162 0.888 0.703,1.12 76 754
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.9333 0.992 0.819,1.2 109 1099 0.9506 0.994 0.821,1.2 109 1097
755 Congenital anomalies of limbs congenital anomalies Both 0.4266 1.04 0.944,1.15 425 4276 0.3475 1.1 0.902,1.34 106 1065
755.1 Congenital deformities of feet congenital anomalies Both 0.4831 0.951 0.826,1.09 208 2086 0.5998 0.963 0.836,1.11 205 2071
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.2851 1.09 0.931,1.28 160 1620 0.3475 1.1 0.902,1.34 106 1065
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.3381 1.1 0.904,1.34 106 1070 0.3475 1.1 0.902,1.34 106 1065
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.5035 0.972 0.894,1.06 587 5872 0.861 0.991 0.899,1.09 428 4332
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.873 1.02 0.819,1.27 81 810 0.8974 1.01 0.815,1.26 80 801
756.5 Congenital osteodystrophies congenital anomalies Both 0.869 0.992 0.9,1.09 435 4356 0.861 0.991 0.899,1.09 428 4332
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.6668 0.965 0.82,1.14 148 1708 0.3758 0.893 0.694,1.15 59 825
758.1 Chromosomal anomalies congenital anomalies Both 0.3758 0.893 0.696,1.15 60 830 0.3758 0.893 0.694,1.15 59 825
759 Other and unspecified congenital anomalies congenital anomalies Both 0.6855 1.03 0.896,1.18 216 2159 0.175 1.15 0.94,1.41 95 948
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.227 1.13 0.926,1.38 96 959 0.175 1.15 0.94,1.41 95 948
760 Back pain symptoms Both 0.5105 1.01 0.987,1.03 11126 111353 0.6607 1.0 0.985,1.02 10911 110601
761 Cervicalgia symptoms Both 0.0257 0.946 0.901,0.993 1791 17901 0.02344 0.945 0.899,0.992 1764 17779
764 Sciatica symptoms Both 0.5675 0.988 0.947,1.03 2372 23732 0.4217 0.983 0.941,1.03 2325 23549
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.863 1.01 0.947,1.07 1172 11738 0.8892 1.0 0.946,1.07 1160 11646
770 Myalgia and myositis unspecified symptoms Both 0.929 0.996 0.919,1.08 631 6311 0.9057 0.995 0.917,1.08 621 6259
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.7499 1.01 0.944,1.08 870 8687 0.7499 1.0 0.975,1.04 4517 45938
771.1 Swelling of limb symptoms Both 0.4446 1.01 0.982,1.04 4617 46330 0.7499 1.0 0.975,1.04 4517 45938
772 Symptoms of the muscles symptoms Both 0.5546 1.02 0.946,1.11 659 6581 0.4677 1.03 0.95,1.12 643 6523
773 Pain in limb symptoms Both 0.08913 1.02 0.997,1.05 6209 62203 0.114 1.02 0.995,1.05 6107 61733
780 Hypothermia/Chills symptoms Both 0.6966 1.03 0.882,1.21 171 1719 0.6295 1.04 0.888,1.22 167 1706
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.9795 1.0 0.954,1.05 1870 18715 0.7328 0.992 0.945,1.04 1820 18586
782.3 Edema symptoms Both 0.3467 1.02 0.974,1.08 1642 16450 0.5821 1.01 0.963,1.07 1557 16291
782.6 Pallor and flushing symptoms Both 0.1936 0.9 0.767,1.06 175 1748 0.2148 0.904 0.77,1.06 173 1733
783 Fever of unknown origin symptoms Both 0.1702 0.977 0.946,1.01 3911 39105 0.1256 0.974 0.942,1.01 3758 38821
785 Abdominal pain symptoms Both 0.3006 0.994 0.984,1.0 40080 301686 0.2767 0.994 0.984,1.0 39603 299757
788 Syncope and collapse symptoms Both 0.4539 0.992 0.971,1.01 9069 90813 0.2649 0.988 0.966,1.01 8907 90002
789 Nausea and vomiting symptoms Both 0.002138 1.03 1.01,1.05 11577 115807 0.009772 1.03 1.01,1.05 11228 115008
790 Nonspecific findings on examination of blood symptoms Both 0.7638 0.975 0.826,1.15 150 1500 0.9376 0.999 0.973,1.03 6240 62964
790.1 Elevated sedimentation rate symptoms Both 0.4055 1.1 0.879,1.38 84 840 0.4074 1.1 0.879,1.37 84 830
790.6 Other abnormal blood chemistry symptoms Both 0.8204 1.0 0.977,1.03 6357 63635 0.9376 0.999 0.973,1.03 6240 62964
791 Gangrene symptoms Both 0.171 1.06 0.974,1.16 549 5501 0.1479 1.07 0.977,1.16 529 5457
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.6501 1.05 0.855,1.29 98 966 0.6792 1.04 0.851,1.28 97 964
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.7889 1.03 0.853,1.23 134 1340 0.004677 0.879 0.803,0.961 533 5601
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.003236 0.877 0.803,0.957 565 5647 0.004677 0.879 0.803,0.961 533 5601
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.863 1.02 0.844,1.22 120 1198 0.863 1.02 0.844,1.22 120 1198
797 Shock symptoms Both 0.4831 0.944 0.803,1.11 156 1559 0.9506 1.01 0.825,1.23 100 1007
797.1 Cardiogenic shock symptoms Both 0.7603 0.97 0.797,1.18 102 1020 0.9506 1.01 0.825,1.23 100 1007
798 Malaise and fatigue symptoms Both 0.007943 1.05 1.01,1.09 3408 34103 0.6668 1.02 0.935,1.11 585 5878
798.1 Chronic fatigue syndrome symptoms Both 0.7674 1.01 0.93,1.1 591 5913 0.6668 1.02 0.935,1.11 585 5878
800 Fracture of lower limb injuries & poisonings Both 0.228 0.985 0.961,1.01 7035 70329 0.9638 0.998 0.927,1.08 758 7593
800.1 Fracture of neck of femur injuries & poisonings Both 0.2046 0.969 0.923,1.02 1815 18152 0.2046 0.969 0.923,1.02 1770 18008
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.6295 1.04 0.888,1.22 170 1693 0.6223 1.04 0.888,1.22 167 1677
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.867 0.996 0.953,1.04 2158 21577 0.8241 0.995 0.952,1.04 2140 21424
800.4 Fracture of patella injuries & poisonings Both 0.8974 0.995 0.924,1.07 766 7661 0.9638 0.998 0.927,1.08 758 7593
801 Fracture of ankle and foot injuries & poisonings Both 0.4236 0.982 0.94,1.03 2205 22041 0.3251 0.976 0.931,1.02 1815 18212
801.1 Fracture of foot injuries & poisonings Both 0.3206 0.976 0.931,1.02 1835 18346 0.3251 0.976 0.931,1.02 1815 18212
802 Fracture of pelvis injuries & poisonings Both 0.389 0.967 0.895,1.04 718 7185 0.3819 0.966 0.894,1.04 710 7132
803 Fracture of upper limb injuries & poisonings Both 0.4539 0.991 0.969,1.01 8288 82880 0.06457 0.951 0.902,1.0 1505 15083
803.1 Fracture of humerus injuries & poisonings Both 0.3483 1.02 0.974,1.08 1691 16883 0.3388 1.02 0.975,1.08 1671 16744
803.2 Fracture of radius and ulna injuries & poisonings Both 0.2748 0.984 0.957,1.01 5215 52171 0.2704 0.984 0.956,1.01 5174 51804
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.06607 0.952 0.903,1.0 1518 15186 0.06457 0.951 0.902,1.0 1505 15083
804 Fracture of hand or wrist injuries & poisonings Both 0.2729 1.02 0.984,1.06 3339 33384 0.3357 1.02 0.982,1.05 3318 33141
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.236 1.03 0.978,1.09 1358 13565 0.2698 1.03 0.976,1.09 1330 13461
807 Fracture of ribs injuries & poisonings Both 0.4227 1.03 0.958,1.11 776 7752 0.5943 1.02 0.948,1.1 762 7679
809 Fracture of unspecified bones injuries & poisonings Both 0.0912 1.05 0.992,1.11 1300 12998 0.13 1.05 0.987,1.11 1287 12897
817 Concussion injuries & poisonings Both 0.2642 1.08 0.946,1.23 243 2428 0.2366 1.08 0.95,1.23 242 2409
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.2393 0.947 0.866,1.04 522 5213 0.241 0.947 0.865,1.04 518 5168
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.7798 0.995 0.957,1.03 2957 29596 0.7079 0.993 0.955,1.03 2931 29383
823 Torus fracture injuries & poisonings Both 0.6383 1.01 0.963,1.06 1673 16710 0.695 1.01 0.961,1.06 1661 16592
830 Dislocation injuries & poisonings Both 0.369 1.02 0.976,1.07 2088 20872 0.4046 1.02 0.974,1.07 2069 20726
835 Internal derangement of knee injuries & poisonings Both 0.6808 0.997 0.98,1.01 15221 152247 0.6699 0.996 0.98,1.01 15135 151180
836 Traumatic arthropathy injuries & poisonings Both 0.4966 1.03 0.943,1.13 526 5267 0.6081 1.02 0.936,1.12 522 5236
840 Sprains and strains injuries & poisonings Both 0.3199 0.953 0.866,1.05 470 4697 0.3228 0.953 0.866,1.05 464 4661
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.1581 1.02 0.992,1.05 5259 52626 0.1914 1.02 0.991,1.05 5155 52215
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.4217 1.07 0.909,1.26 157 1567 0.811 1.02 0.864,1.21 150 1551
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.2685 1.05 0.961,1.15 501 5010 0.3258 1.05 0.954,1.15 487 4979
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.526 1.02 0.968,1.07 1826 18238 0.673 1.01 0.962,1.06 1767 18059
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.873 1.0 0.948,1.07 1241 12418 0.8337 1.01 0.949,1.07 1223 12313
858 Complication of internal orthopedic device injuries & poisonings Both 0.2911 0.98 0.945,1.02 3158 31607 0.2328 0.978 0.942,1.01 3132 31344
859 Complication due to other implant and internal device injuries & poisonings Both 0.134 1.03 0.992,1.07 3259 32599 0.2399 1.02 0.986,1.06 3172 32340
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.0309 1.04 1.0,1.08 3502 35062 0.6902 1.05 0.825,1.34 67 672
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.7079 0.977 0.863,1.1 272 2713 0.7328 0.979 0.865,1.11 272 2692
870.2 Open wound of ear injuries & poisonings Both 0.6918 1.03 0.891,1.19 196 1949 0.6823 1.03 0.89,1.19 190 1938
870.3 Other open wound of head and face injuries & poisonings Both 0.4529 1.01 0.977,1.05 2904 29085 0.5458 1.01 0.974,1.05 2857 28854
870.4 Open wound of nose and sinus injuries & poisonings Both 0.03715 1.16 1.01,1.33 220 2199 0.04169 1.16 1.01,1.33 215 2178
870.6 Open wound of neck injuries & poisonings Both 0.5023 1.09 0.855,1.38 68 678 0.6902 1.05 0.825,1.34 67 672
871 Open wounds of extremities injuries & poisonings Both 0.04266 0.967 0.937,0.999 4063 40648 0.8035 1.02 0.874,1.19 174 1774
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.2339 0.837 0.625,1.12 53 530 0.2178 0.829 0.616,1.12 51 524
871.2 Open wound of finger(s) injuries & poisonings Both 0.7816 1.03 0.834,1.27 91 900 0.7762 1.03 0.834,1.28 90 890
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.6902 1.03 0.886,1.2 178 1785 0.8035 1.02 0.874,1.19 174 1774
872 Traumatic amputation injuries & poisonings Both 0.1986 1.06 0.968,1.17 475 4742 0.1849 1.07 0.97,1.17 469 4697
873 Broken tooth injuries & poisonings Both 0.7816 1.02 0.891,1.17 229 2289 0.7063 1.03 0.897,1.18 228 2262
874 Complication of amputation stump injuries & poisonings Both 0.9572 1.0 0.859,1.17 169 1710 0.8954 1.01 0.863,1.18 166 1701
905 Late effects of musculoskeletal and connective tissue injuries injuries & poisonings Both 0.3148 0.919 0.779,1.08 157 1567 0.3069 0.917 0.777,1.08 157 1556
907 Injuries to the nervous system injuries & poisonings Both 0.6427 0.987 0.932,1.04 1314 13140 0.673 0.988 0.933,1.05 1303 13051
915 Superficial injury without mention of infection injuries & poisonings Both 0.3199 0.984 0.954,1.02 4260 42663 0.375 0.986 0.955,1.02 4203 42345
916 Contusion injuries & poisonings Both 0.3673 1.03 0.971,1.08 1450 14506 0.4624 1.02 0.966,1.08 1433 14399
930 Allergic reaction to food injuries & poisonings Both 0.7244 0.972 0.832,1.14 179 1807 0.7516 0.975 0.834,1.14 179 1794
938 Dermatitis due to solar radiation injuries & poisonings Both 0.7244 0.981 0.884,1.09 389 3899 0.5082 0.957 0.84,1.09 250 2506
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.5702 0.963 0.845,1.1 252 2530 0.5082 0.957 0.84,1.09 250 2506
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.9863 1.0 0.872,1.15 225 2249 0.9638 1.0 0.874,1.15 223 2226
942 Infusion and transfusion reaction injuries & poisonings Both 0.6668 1.05 0.854,1.28 104 1038 0.5781 1.06 0.864,1.3 100 1028
946 Anaphylactic shock NOS injuries & poisonings Both 0.4498 1.03 0.947,1.13 550 5509 0.3945 1.04 0.951,1.14 541 5458
947 Urticaria injuries & poisonings Both 0.7047 0.98 0.881,1.09 371 3707 0.7311 0.982 0.882,1.09 365 3681
949 Allergies, other injuries & poisonings Both 0.8511 0.99 0.893,1.1 397 3989 0.9162 0.994 0.897,1.1 395 3965
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.8091 1.01 0.916,1.12 423 4224 0.9572 1.0 0.907,1.11 417 4189
957 Injury to other and unspecified nerves injuries & poisonings Both 0.3846 0.946 0.834,1.07 269 2698 0.3622 0.943 0.83,1.07 265 2674
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.2317 1.06 0.965,1.16 491 4926 0.9311 1.01 0.796,1.28 72 734
958.1 Postoperative shock injuries & poisonings Both 0.871 1.02 0.774,1.35 55 555 0.8892 1.02 0.772,1.35 55 551
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.929 1.01 0.799,1.28 74 740 0.9311 1.01 0.796,1.28 72 734
960 Poisoning by antibiotics injuries & poisonings Both 0.07413 1.01 0.999,1.03 18100 181147 0.05495 1.02 1.0,1.03 15615 157625
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.02239 1.02 1.0,1.04 15846 158623 0.05495 1.02 1.0,1.03 15615 157625
961 Poisoning by other anti-infectives injuries & poisonings Both 0.7261 1.02 0.922,1.12 420 4195 0.4508 0.973 0.907,1.04 855 8655
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.4721 0.975 0.909,1.05 869 8703 0.4508 0.973 0.907,1.04 855 8655
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.2275 1.07 0.96,1.19 371 3707 0.2158 1.07 0.96,1.2 342 3610
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.2228 1.07 0.96,1.19 364 3638 0.2158 1.07 0.96,1.2 342 3610
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.9772 0.998 0.867,1.15 223 2228 0.9772 0.998 0.866,1.15 218 2220
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.09772 1.11 0.982,1.25 282 2830 0.2239 1.08 0.954,1.22 269 2740
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.2123 1.08 0.957,1.22 276 2770 0.2239 1.08 0.954,1.22 269 2740
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.2877 0.986 0.96,1.01 6082 60875 0.302 0.948 0.856,1.05 395 4017
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.7889 1.01 0.949,1.07 1144 11447 0.7943 1.01 0.948,1.07 1122 11366
965.2 Antirheumatics causing adverse effects in therapeutic use injuries & poisonings Both 0.869 0.992 0.904,1.09 476 4767 0.9572 0.997 0.908,1.1 468 4744
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.3483 0.953 0.862,1.05 403 4045 0.302 0.948 0.856,1.05 395 4017
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.3648 0.958 0.873,1.05 512 5123 0.3802 0.959 0.874,1.05 507 5099
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.4325 0.966 0.887,1.05 583 5843 0.5636 0.975 0.895,1.06 574 5803
969 Poisoning by psychotropic agents injuries & poisonings Both 0.6053 1.01 0.967,1.06 1950 19519 0.5902 1.01 0.967,1.06 1909 19455
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.2564 1.09 0.939,1.26 190 1908 0.2553 1.09 0.94,1.26 190 1897
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.369 1.06 0.936,1.19 271 2717 0.3776 1.11 0.883,1.39 83 844
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.415 1.1 0.876,1.38 84 849 0.3776 1.11 0.883,1.39 83 844
973 Poisoning by agents primarily affecting the gastrointestinal system injuries & poisonings Both 0.4966 1.07 0.88,1.3 108 1080 0.3828 1.09 0.897,1.33 107 1076
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.03467 1.23 1.02,1.5 101 1018 0.06918 1.2 0.986,1.46 99 1005
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.2404 1.17 0.901,1.51 64 640 0.2133 1.18 0.91,1.53 64 633
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.859 1.02 0.782,1.34 58 580 0.857 1.03 0.779,1.35 56 575
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.3648 1.06 0.931,1.22 234 2337 0.5309 1.04 0.912,1.2 226 2324
979 Adverse drug events and drug allergies injuries & poisonings Both 0.7295 0.986 0.913,1.07 698 6966 0.6761 0.983 0.909,1.06 681 6936
981 Toxic effect of (non-ethyl) alcohol and petroleum and other solvents injuries & poisonings Both 0.4159 0.941 0.814,1.09 200 1999 0.4246 0.942 0.813,1.09 195 1992
986 Toxic effect of carbon monoxide injuries & poisonings Both 0.877 0.98 0.758,1.27 62 620 0.6516 0.941 0.724,1.22 59 617
987 Toxic effect of other gases, fumes, or vapors injuries & poisonings Both 0.526 1.06 0.88,1.28 105 1049 0.4064 1.09 0.894,1.32 99 1039
988 Toxic effect of noxious substances eaten as food injuries & poisonings Both 0.7798 0.972 0.799,1.18 111 1128 0.8017 0.975 0.801,1.19 111 1118
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.1714 1.16 0.939,1.43 89 890 0.1592 1.19 0.934,1.52 64 881
990 Effects radiation NOS injuries & poisonings Both 0.867 0.997 0.961,1.03 3113 31140 0.1271 0.97 0.932,1.01 2702 30900
994 Sepsis and SIRS injuries & poisonings Both 0.00389 1.06 1.02,1.1 3028 30268 0.00871 1.05 1.01,1.09 2833 30015
994.2 Sepsis injuries & poisonings Both 0.00389 1.06 1.02,1.1 3028 30268 0.00871 1.05 1.01,1.09 2833 30015
1000 Burns injuries & poisonings Both 0.9247 1.0 0.923,1.09 578 5796 0.9162 0.995 0.914,1.08 571 5746
1001 Foreign body injury injuries & poisonings Both 0.9099 1.0 0.946,1.06 1199 12007 1.0 1.0 0.942,1.06 1174 11912
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 3.236E-4 1.05 1.02,1.08 5480 54819 9.333E-4 1.05 1.02,1.08 5311 54384
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.7211 0.979 0.869,1.1 300 2997 0.6531 0.973 0.862,1.1 288 2979
1005 Other symptoms injuries & poisonings Both 0.5808 1.02 0.962,1.07 1444 14422 0.6124 1.01 0.959,1.07 1343 14299
1006 Crushing injury injuries & poisonings Both 0.4966 1.05 0.919,1.19 256 2558 0.547 1.04 0.914,1.18 254 2540
1007 Injury to blood vessels injuries & poisonings Both 0.01905 1.17 1.03,1.32 256 2559 0.009333 1.19 1.04,1.35 250 2546
1008 Crushing or internal injury to organs injuries & poisonings Both 0.4159 1.03 0.963,1.1 1013 10132 0.5888 1.02 0.953,1.09 990 10058
1009 Injury, NOS injuries & poisonings Both 0.2037 1.01 0.992,1.04 8482 84911 0.3319 1.01 0.989,1.03 8383 84284
1010 Other tests injuries & poisonings Both 0.0871 1.02 0.997,1.05 5945 59512 0.1936 1.02 0.991,1.05 5805 59045
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.2344 1.01 0.992,1.04 9152 91588 0.4645 1.01 0.986,1.03 8842 90839
1012 Late effect injuries & poisonings Both 0.08511 1.19 0.976,1.45 105 1057 0.06918 1.2 0.986,1.46 104 1050
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.4831 0.959 0.853,1.08 316 3168 0.5821 0.967 0.858,1.09 299 3139
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3162 0.879 0.684,1.13 66 659 0.3062 0.877 0.682,1.13 66 656
1015 Effects of other external causes injuries & poisonings Both 0.1698 1.02 0.991,1.06 4226 42294 0.2449 1.02 0.987,1.05 4141 41989
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.7889 0.998 0.982,1.01 15895 159019 0.6714 0.996 0.98,1.01 15663 157925
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LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

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