Cancer-PRSweb GSE


  • Home
  • Search Phecode
  • Method
  • Contact
  • News
  • PRS Overview
PRSweb Skip to content…
MGI PRS for Colon cancer(153.2) based on UKB GWAS (FINNGEN)
GWAS reference: !UKB_GWAS GWAS source: UKB GWAS (FINNGEN) PRS method: Lassosum
PRSweb LD reference: UKB GWAS phenotype: Malignant neoplasm of colon PRSweb date: 2020-06-20
GWAS ID: C3_COLON GWAS URL: http://www.nealelab.is/uk-biobank Genome build: GRCh37/hg19
PRS tuning parameter: s=1;Lambda=0.001 PRS evaluation in: MGI
  • Graph
  • Table
Download the table:
CSV EXCEL
PRS PheWAS Summary Statistics Exclusion PRS PheWAS Summary Statistics
PheWAS
Code		 Description Category Sex P value Odds
Ratio 		95% CI # Cases # Controls P value Odds
Ratio		 95% CI # Cases # Controls
008 Intestinal infection infectious diseases Both 0.542 1.01 0.971,1.06 2317 23065 0.4699 0.975 0.91,1.04 874 9028
008.5 Bacterial enteritis infectious diseases Both 0.6887 1.01 0.952,1.08 1090 10875 0.4178 1.03 0.959,1.11 813 8653
008.52 Intestinal infection due to C. difficile infectious diseases Both 0.3819 1.03 0.963,1.1 896 8939 0.4178 1.03 0.959,1.11 813 8653
008.6 Viral Enteritis infectious diseases Both 0.5093 0.972 0.892,1.06 590 5900 0.6653 0.981 0.898,1.07 560 5736
010 Tuberculosis infectious diseases Both 0.8531 0.986 0.849,1.14 195 1948 0.5333 0.994 0.973,1.01 18261 18901
031 Diseases due to other mycobacteria infectious diseases Both 0.8531 1.02 0.795,1.32 73 722 0.7079 0.95 0.727,1.24 67 703
038 Septicemia infectious diseases Both 0.3228 1.02 0.978,1.07 2043 20052 0.6252 1.02 0.949,1.09 870 9189
038.1 Gram negative septicemia infectious diseases Both 0.863 0.992 0.901,1.09 459 4559 0.7096 0.981 0.888,1.08 417 4417
038.2 Gram positive septicemia infectious diseases Both 0.7727 1.02 0.881,1.19 184 1840 0.8395 1.02 0.872,1.18 174 1789
038.3 Bacteremia infectious diseases Both 0.6486 1.02 0.95,1.09 955 9489 0.6252 1.02 0.949,1.09 870 9189
041 Bacterial infection NOS infectious diseases Both 0.4909 0.989 0.959,1.02 4641 32299 0.9931 1.0 0.866,1.16 207 2190
041.1 Staphylococcus infections infectious diseases Both 0.6902 0.989 0.936,1.04 1390 13828 0.8147 1.01 0.928,1.1 599 6217
041.11 Methicillin sensitive Staphylococcus aureus infectious diseases Both 0.5675 0.978 0.905,1.06 714 7071 0.5689 0.977 0.903,1.06 676 6882
041.12 Methicillin resistant Staphylococcus aureus infectious diseases Both 0.6577 1.02 0.939,1.11 639 6376 0.8147 1.01 0.928,1.1 599 6217
041.2 Streptococcus infection infectious diseases Both 0.09772 0.953 0.901,1.01 1316 13131 0.8851 0.99 0.859,1.14 201 1981
041.21 Rheumatic fever / chorea infectious diseases Both 0.8166 0.984 0.855,1.13 205 2047 0.8851 0.99 0.859,1.14 201 1981
041.4 E. coli infectious diseases Both 0.06026 1.07 0.997,1.14 949 9462 0.03311 1.08 1.01,1.16 849 9169
041.8 H. pylori infectious diseases Both 0.2128 1.1 0.948,1.27 190 1892 0.1592 1.11 0.959,1.29 180 1839
041.9 Infection with drug-resistant microorganisms infectious diseases Both 0.7656 1.02 0.89,1.17 228 2265 0.9931 1.0 0.866,1.16 207 2190
053 Herpes zoster infectious diseases Both 0.3882 1.03 0.967,1.09 1184 11746 0.8414 0.984 0.836,1.16 156 1598
053.1 Herpes zoster with nervous system complications infectious diseases Both 0.8995 0.99 0.845,1.16 166 1655 0.8414 0.984 0.836,1.16 156 1598
054 Herpes simplex infectious diseases Both 0.5093 1.02 0.962,1.08 1235 12278 0.6561 1.01 0.955,1.08 1187 11948
070 Viral hepatitis infectious diseases Both 0.8017 1.01 0.933,1.09 661 6584 0.4467 0.973 0.908,1.04 875 8923
070.1 Viral hepatitis A infectious diseases Both 0.0912 1.25 0.965,1.62 67 660 0.03548 1.34 1.02,1.76 62 642
070.2 Viral hepatitis B infectious diseases Both 0.8551 1.02 0.864,1.19 162 1620 0.8395 0.983 0.832,1.16 149 1569
070.3 Viral hepatitis C infectious diseases Both 0.5176 0.969 0.88,1.07 439 4366 0.4018 0.959 0.87,1.06 421 4229
070.4 Chronic hepatitis infectious diseases Both 0.8222 0.982 0.836,1.15 161 1610 0.9977 1.0 0.849,1.18 154 1570
070.9 Hepatitis NOS infectious diseases Both 0.7656 0.99 0.925,1.06 924 9231 0.4467 0.973 0.908,1.04 875 8923
071 Human immunodeficiency virus [HIV] disease infectious diseases Both 0.3864 0.92 0.761,1.11 122 1220 0.03715 0.773 0.607,0.984 72 925
071.1 HIV infection, symptomatic infectious diseases Both 0.1033 0.837 0.676,1.04 95 950 0.03715 0.773 0.607,0.984 72 925
078 Viral warts & HPV infectious diseases Both 0.881 0.997 0.958,1.04 2651 24185 0.9795 1.0 0.96,1.04 2511 23550
079 Viral infection infectious diseases Both 0.4887 0.989 0.96,1.02 5061 29504 0.456 0.967 0.887,1.06 560 5565
079.1 Varicella infection infectious diseases Both 0.6152 0.99 0.953,1.03 2940 25647 0.7278 0.993 0.955,1.03 2819 24901
079.2 Infectious mononucleosis infectious diseases Both 0.3698 1.07 0.926,1.23 213 2093 0.3926 1.07 0.922,1.23 204 2053
079.9 Viremia, NOS infectious diseases Both 0.3589 0.961 0.882,1.05 579 5713 0.456 0.967 0.887,1.06 560 5565
080 Postoperative infection infectious diseases Both 0.07762 1.04 0.996,1.08 2586 25769 0.1288 1.03 0.991,1.08 2404 24997
081 Infection/inflammation of internal prosthetic device; implant; and graft infectious diseases Both 0.3639 0.975 0.922,1.03 1364 13616 0.5012 0.981 0.926,1.04 1293 13204
090 Sexually transmitted infections (not HIV or hepatitis) infectious diseases Both 0.9354 0.997 0.922,1.08 700 6990 0.7096 1.02 0.937,1.1 665 6811
110 Dermatophytosis / Dermatomycosis infectious diseases Both 0.01445 0.948 0.909,0.99 2379 23308 0.5093 1.05 0.909,1.21 204 2162
110.1 Dermatophytosis infectious diseases Both 0.0871 0.962 0.92,1.01 2164 21163 0.6871 0.982 0.9,1.07 550 5508
110.11 Dermatophytosis of nail infectious diseases Both 0.06166 0.946 0.893,1.0 1264 12489 0.04677 0.942 0.887,0.999 1210 12057
110.12 Althete's foot infectious diseases Both 0.1923 0.945 0.868,1.03 593 5884 0.1824 0.943 0.865,1.03 571 5711
110.13 Dermatophytosis of the body infectious diseases Both 0.7194 0.984 0.904,1.07 570 5682 0.6871 0.982 0.9,1.07 550 5508
110.2 Dermatomycoses infectious diseases Both 0.002239 0.826 0.73,0.934 283 2812 0.001622 0.818 0.722,0.927 273 2744
112 Candidiasis infectious diseases Both 0.4385 0.985 0.948,1.02 2931 25310 0.3819 0.961 0.878,1.05 520 5271
112.3 Candidiasis of skin and nails infectious diseases Both 0.4539 0.967 0.886,1.06 546 5450 0.3819 0.961 0.878,1.05 520 5271
117 Mycoses infectious diseases Both 0.3214 0.954 0.869,1.05 494 4925 0.984 1.0 0.818,1.23 103 1003
117.1 Histoplasmosis infectious diseases Both 0.6266 1.06 0.827,1.37 66 660 0.5623 1.08 0.828,1.41 58 639
117.4 Aspergillosis infectious diseases Both 0.9616 1.0 0.822,1.23 105 1045 0.984 1.0 0.818,1.23 103 1003
130 Spirochetal infection infectious diseases Both 0.4436 0.932 0.777,1.12 118 1177 0.3076 0.89 0.712,1.11 82 832
130.1 Lyme disease infectious diseases Both 0.2371 0.876 0.704,1.09 86 860 0.3076 0.89 0.712,1.11 82 832
132 Infestation (lice, mites) infectious diseases Both 0.1213 1.14 0.965,1.36 146 1460 0.1191 1.15 0.966,1.36 142 1413
134 Helminthiases infectious diseases Both 0.3105 1.15 0.876,1.52 54 540 ,
136 Other infectious and parasitic diseases infectious diseases Both 0.8472 1.0 0.963,1.05 2438 24314 0.8531 1.0 0.962,1.05 2306 23550
980 Encounter for long-term (current) use of antibiotics infectious diseases Both 0.7345 1.01 0.951,1.07 1166 11657 0.7709 1.01 0.949,1.07 1106 11267
145 Cancer of mouth neoplasms Both 0.8204 1.01 0.949,1.07 1182 11759 0.7516 1.03 0.88,1.19 167 1644
145.1 Cancer of lip neoplasms Both 0.6486 1.06 0.829,1.35 69 690 0.7047 1.05 0.821,1.34 68 671
145.2 Cancer of tongue neoplasms Both 0.8913 0.994 0.911,1.08 550 5486 0.7925 0.988 0.905,1.08 539 5251
145.3 Cancer of major salivary glands neoplasms Both 0.003162 1.19 1.06,1.34 310 3093 0.004467 1.19 1.05,1.34 300 2969
145.4 Cancer of the gums neoplasms Both 0.7798 0.976 0.821,1.16 143 1419 0.6353 0.959 0.806,1.14 140 1360
145.5 Cancer of the mouth floor neoplasms Both 0.5321 1.05 0.902,1.22 173 1723 0.7516 1.03 0.88,1.19 167 1644
149 Cancer of larynx, pharynx, nasal cavities neoplasms Both 0.6324 0.985 0.927,1.05 1124 11202 0.9528 1.0 0.87,1.16 203 1975
149.1 Cancer of oropharynx neoplasms Both 0.4819 0.958 0.85,1.08 291 2892 0.5458 0.964 0.855,1.09 288 2774
149.2 Cancer of nasopharynx neoplasms Both 0.561 0.936 0.748,1.17 87 855 0.6871 0.955 0.761,1.2 85 826
149.3 Cancer of hypopharynx neoplasms Both 0.7603 1.04 0.815,1.32 68 680 0.7015 1.05 0.824,1.33 68 647
149.4 Cancer of larynx neoplasms Both 0.8356 0.988 0.883,1.11 332 3314 0.8204 0.987 0.88,1.11 327 3187
149.5 Hx of malignant neoplasm of oral cavity and pharynx neoplasms Both 0.4592 1.03 0.945,1.13 505 5041 0.415 1.04 0.948,1.14 497 4853
149.9 Cancer of of nasal cavities neoplasms Both 0.5754 1.04 0.904,1.2 208 2067 0.9528 1.0 0.87,1.16 203 1975
150 Cancer of esophagus neoplasms Both 0.5105 1.04 0.934,1.15 378 3776 0.5023 1.04 0.932,1.15 355 3776
151 Cancer of stomach neoplasms Both 0.9141 0.995 0.9,1.1 430 4292 0.9727 1.0 0.898,1.12 353 4292
153 Colorectal cancer neoplasms Both 5.623E-4 1.11 1.05,1.18 1196 11882 ,
153.2 Colon cancer neoplasms Both 2.239E-4 1.14 1.06,1.21 941 9327 ,
153.3 Malignant neoplasm of rectum, rectosigmoid junction, and anus neoplasms Both 0.04266 1.09 1.0,1.18 669 6663 ,
155 Cancer of liver and intrahepatic bile duct neoplasms Both 0.4603 1.04 0.94,1.15 418 4180 0.4276 1.06 0.923,1.21 227 2850
155.1 Malignant neoplasm of liver, primary neoplasms Both 0.2075 1.08 0.957,1.22 285 2850 0.4276 1.06 0.923,1.21 227 2850
157 Pancreatic cancer neoplasms Both 0.2061 0.939 0.851,1.04 430 4292 0.1052 0.918 0.828,1.02 386 4292
158 Neoplasm of unspecified nature of digestive system neoplasms Both 0.526 1.02 0.963,1.08 1369 13455 0.6966 1.01 0.953,1.08 1119 13455
159 Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum neoplasms Both 0.7586 0.989 0.919,1.06 779 7785 0.9506 0.996 0.864,1.15 211 2550
159.2 Malignant neoplasm of small intestine, including duodenum neoplasms Both 0.1377 0.898 0.779,1.04 183 1830 0.0537 0.838 0.7,1.0 108 1830
159.3 Malignant neoplasm of gallbladder and extrahepatic bile ducts neoplasms Both 0.869 0.985 0.825,1.18 133 1330 0.537 0.942 0.778,1.14 113 1330
159.4 Malignant neoplasm of retroperitoneum and peritoneum neoplasms Both 0.9863 0.999 0.878,1.14 255 2550 0.9506 0.996 0.864,1.15 211 2550
164 Cancer of intrathoracic organs neoplasms Both 0.03388 1.23 1.02,1.5 111 1110 0.04074 1.23 1.01,1.5 106 1078
165 Cancer within the respiratory system neoplasms Both 0.4159 1.03 0.962,1.1 945 9436 0.9247 0.997 0.927,1.07 810 8414
165.1 Cancer of bronchus; lung neoplasms Both 0.5984 1.02 0.95,1.09 874 8724 0.9247 0.997 0.927,1.07 810 8414
170 Cancer of bone and connective tissue neoplasms Both 0.9441 0.998 0.947,1.05 1538 15304 0.6699 1.01 0.951,1.08 1002 10565
170.1 Bone cancer neoplasms Both 0.631 0.981 0.906,1.06 668 6660 0.4529 0.969 0.894,1.05 645 6419
170.2 Cancer of connective tissue neoplasms Both 0.5598 1.02 0.957,1.08 1097 10941 0.6699 1.01 0.951,1.08 1002 10565
172 Skin cancer neoplasms Both 0.2133 0.983 0.957,1.01 7099 27878 0.867 0.995 0.935,1.06 1134 9920
172.1 Melanomas of skin, dx or hx neoplasms Both 0.5212 0.987 0.948,1.03 2701 21867 0.6383 0.99 0.95,1.03 2521 20838
172.11 Melanomas of skin neoplasms Both 0.4721 0.985 0.946,1.03 2624 21526 0.6383 0.99 0.95,1.03 2521 20838
172.2 Other non-epithelial cancer of skin neoplasms Both 0.1143 0.977 0.948,1.01 5888 25669 0.5888 0.986 0.939,1.04 1814 14071
172.21 Basal cell carcinoma neoplasms Both 0.2099 0.975 0.938,1.01 2988 20068 0.2818 0.978 0.94,1.02 2844 19408
172.22 Squamous cell carcinoma neoplasms Both 0.5321 0.985 0.938,1.03 1917 14585 0.5888 0.986 0.939,1.04 1814 14071
172.3 Carcinoma in situ of skin neoplasms Both 0.6486 0.986 0.929,1.05 1215 10290 0.867 0.995 0.935,1.06 1134 9920
173 Neoplasm of uncertain behavior of skin neoplasms Both 0.5012 1.02 0.966,1.07 1575 15093 0.3319 1.03 0.973,1.08 1495 14607
174 Breast cancer neoplasms Both 0.1837 1.03 0.987,1.07 2694 13131 0.9333 0.994 0.862,1.15 201 1986
174.1 Breast cancer [female] neoplasms Female 0.07586 1.04 0.996,1.08 2605 12548 0.04786 1.05 1.0,1.09 2475 12223
174.11 Malignant neoplasm of female breast neoplasms Female 0.06607 1.04 0.997,1.09 2565 12510 0.04786 1.05 1.0,1.09 2475 12223
174.3 Neoplasm of uncertain behavior of breast neoplasms Both 0.859 1.01 0.88,1.17 206 2051 0.9333 0.994 0.862,1.15 201 1986
175 Acquired absence of breast neoplasms Female 0.5984 1.02 0.952,1.09 978 9172 0.5272 1.02 0.955,1.09 947 8964
180 Cervical cancer and dysplasia neoplasms Female 0.5495 1.02 0.959,1.08 1182 10494 0.6368 1.02 0.946,1.09 815 7756
180.1 Cervical cancer neoplasms Female 0.2163 1.06 0.964,1.18 430 4300 0.369 1.05 0.946,1.16 404 4199
180.3 Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia] neoplasms Female 0.8241 1.01 0.939,1.08 857 7886 0.6368 1.02 0.946,1.09 815 7756
182 Malignant neoplasm of uterus neoplasms Female 0.03236 1.09 1.01,1.19 643 6390 0.0309 1.1 1.01,1.19 604 6196
184 Cancer of other female genital organs neoplasms Female 0.4256 1.03 0.96,1.1 910 8957 0.1002 1.08 0.985,1.19 456 5112
184.1 Malignant neoplasm of ovary and other uterine adnexa neoplasms Female 0.1442 1.07 0.977,1.18 491 4888 0.3041 1.06 0.948,1.19 339 3579
184.11 Malignant neoplasm of ovary neoplasms Female 0.1479 1.08 0.972,1.21 367 3659 0.3041 1.06 0.948,1.19 339 3579
184.2 Cancer of other female genital organs (excluding uterus and ovary) neoplasms Female 0.3069 1.05 0.958,1.15 526 5253 0.1002 1.08 0.985,1.19 456 5112
185 Cancer of prostate neoplasms Male 0.9954 1.0 0.954,1.05 2432 8825 0.9683 0.999 0.952,1.05 2334 8501
187 Cancer of other male genital organs neoplasms Male 0.7499 0.98 0.867,1.11 276 2723 0.4508 0.935 0.786,1.11 139 1340
187.1 Malignant neoplasm of unspecified male genital organ neoplasms Male 0.1923 1.15 0.934,1.4 96 960 0.1151 1.19 0.959,1.47 88 924
187.2 Malignant neoplasm of testis neoplasms Male 0.3467 0.921 0.777,1.09 144 1387 0.4508 0.935 0.786,1.11 139 1340
189 Cancer of urinary organs (incl. kidney and bladder) neoplasms Both 0.9419 0.998 0.958,1.04 2552 20553 0.413 1.04 0.951,1.13 563 5598
189.1 Cancer of kidney and renal pelvis neoplasms Both 0.9795 0.999 0.944,1.06 1261 12588 0.9036 1.01 0.874,1.17 189 1926
189.11 Malignant neoplasm of kidney, except pelvis neoplasms Both 0.9016 0.996 0.936,1.06 1083 10823 0.9817 0.999 0.938,1.06 1025 10452
189.12 Malignant neoplasm of renal pelvis neoplasms Both 0.863 1.01 0.88,1.16 202 2010 0.9036 1.01 0.874,1.17 189 1926
189.2 Cancer of bladder neoplasms Both 0.6166 1.01 0.962,1.07 1575 13516 0.4519 1.02 0.966,1.08 1371 12066
189.21 Malignant neoplasm of bladder neoplasms Both 0.4325 1.02 0.968,1.08 1456 12558 0.4519 1.02 0.966,1.08 1371 12066
189.4 Malignant neoplasm of other urinary organs neoplasms Both 0.3304 1.04 0.959,1.13 601 5841 0.413 1.04 0.951,1.13 563 5598
190 Cancer of eye neoplasms Both 0.9204 1.01 0.836,1.22 114 1125 0.9661 1.0 0.83,1.21 112 1073
191 Manlignant and unknown neoplasms of brain and nervous system neoplasms Both 0.3365 1.03 0.966,1.11 904 9040 0.1837 1.07 0.97,1.17 469 4688
191.1 Cancer of brain and nervous system neoplasms Both 0.4111 1.04 0.952,1.13 580 5800 0.1837 1.07 0.97,1.17 469 4688
191.11 Cancer of brain neoplasms Both 0.1563 1.07 0.975,1.17 483 4830 0.1837 1.07 0.97,1.17 469 4688
193 Thyroid cancer neoplasms Both 0.3296 1.04 0.964,1.11 798 7953 0.3304 1.04 0.964,1.12 785 7703
194 Cancer of other endocrine glands neoplasms Both 0.3097 1.07 0.935,1.23 221 2207 0.2716 1.08 0.94,1.24 215 2136
195 Cancer, suspected or other neoplasms Both 0.3589 1.01 0.988,1.03 12134 23141 0.7063 1.01 0.947,1.08 941 8862
195.1 Malignant neoplasm, other neoplasms Both 0.3606 1.01 0.987,1.04 11693 23098 0.5689 1.01 0.983,1.03 10816 22910
195.3 Malignant neoplasm of head, face, and neck neoplasms Both 0.5689 1.02 0.954,1.09 970 8963 0.7063 1.01 0.947,1.08 941 8862
196 Radiotherapy neoplasms Both 0.1197 1.04 0.991,1.09 2067 15612 0.1644 1.03 0.986,1.08 1933 15451
197 Chemotherapy neoplasms Both 0.05248 1.03 1.0,1.07 4051 21210 0.05754 1.04 0.999,1.07 3636 21023
198 Secondary malignant neoplasm neoplasms Both 0.03162 1.04 1.0,1.07 4986 21474 0.09772 0.9 0.794,1.02 272 2713
198.1 Secondary malignancy of lymph nodes neoplasms Both 0.118 1.03 0.992,1.07 3156 19844 0.1535 1.03 0.989,1.07 2887 19661
198.2 Secondary malignancy of respiratory organs neoplasms Both 0.5058 1.02 0.956,1.1 903 8847 0.5585 1.02 0.95,1.1 787 8749
198.3 Secondary malignant neoplasm of digestive systems neoplasms Both 0.9226 1.0 0.93,1.08 725 7166 0.8091 0.989 0.905,1.08 519 7088
198.4 Secondary malignant neoplasm of liver neoplasms Both 0.3192 1.04 0.961,1.13 643 6395 0.7261 1.02 0.925,1.12 450 6332
198.5 Secondary malignancy of brain/spine neoplasms Both 0.7816 1.01 0.927,1.11 545 5421 0.8913 1.01 0.919,1.1 510 5365
198.6 Secondary malignancy of bone neoplasms Both 0.1517 0.945 0.875,1.02 712 6962 0.1074 0.936 0.864,1.01 654 6884
198.7 Secondary malignant neoplasm of skin neoplasms Both 0.1194 0.908 0.804,1.03 287 2752 0.09772 0.9 0.794,1.02 272 2713
199 Neoplasm of uncertain behavior neoplasms Both 0.3819 0.986 0.956,1.02 4947 22823 0.4046 0.906 0.717,1.14 71 715
199.4 Neurofibromatosis neoplasms Both 0.455 0.915 0.726,1.15 72 720 0.4046 0.906 0.717,1.14 71 715
200 Myeloproliferative disease neoplasms Both 0.9204 1.0 0.937,1.08 886 8851 0.8531 1.02 0.864,1.19 153 1562
200.1 Polycythemia vera neoplasms Both 0.879 0.988 0.844,1.16 161 1610 0.8531 1.02 0.864,1.19 153 1562
201 Hodgkin's disease neoplasms Both 0.354 1.09 0.911,1.3 138 1373 0.302 1.1 0.918,1.32 131 1335
202 Cancer of other lymphoid, histiocytic tissue neoplasms Both 0.597 0.985 0.931,1.04 1308 13070 0.6209 1.05 0.875,1.25 125 1252
202.2 Non-Hodgkins lymphoma neoplasms Both 0.9572 0.998 0.94,1.06 1141 11402 0.6209 1.05 0.875,1.25 125 1252
202.21 Nodular lymphoma neoplasms Both 0.5408 1.03 0.946,1.11 632 6320 0.8035 1.01 0.93,1.1 597 6094
202.22 Reticulosarcoma neoplasms Both 0.8433 1.02 0.855,1.21 137 1355 0.9772 1.0 0.837,1.2 128 1303
202.24 Large cell lymphoma neoplasms Both 0.5794 1.05 0.883,1.25 132 1300 0.6209 1.05 0.875,1.25 125 1252
204 Leukemia neoplasms Both 0.08128 0.925 0.848,1.01 545 5450 0.7816 0.978 0.837,1.14 170 1729
204.1 Lymphoid leukemia neoplasms Both 0.984 1.0 0.864,1.16 187 1870 0.8472 0.982 0.821,1.18 127 1295
204.11 Lymphoid leukemia, acute neoplasms Both 0.8472 0.976 0.759,1.25 58 580 0.6339 0.94 0.729,1.21 56 559
204.12 Lymphoid leukemia, chronic neoplasms Both 0.7745 1.03 0.862,1.22 136 1350 0.8472 0.982 0.821,1.18 127 1295
204.2 Myeloid leukemia neoplasms Both 0.03715 0.859 0.745,0.991 206 2060 0.1346 0.866 0.717,1.05 120 1199
204.21 Myeloid leukemia, acute neoplasms Both 0.1225 0.864 0.717,1.04 124 1240 0.1346 0.866 0.717,1.05 120 1199
204.4 Multiple myeloma neoplasms Both 0.4395 0.942 0.808,1.1 180 1795 0.7816 0.978 0.837,1.14 170 1729
208 Benign neoplasm of colon neoplasms Both 0.05012 1.03 1.0,1.05 8098 29324 0.1466 1.02 0.993,1.05 7374 29324
209 Neuroendocrine tumors neoplasms Both 0.8453 1.01 0.884,1.16 222 2220 0.6871 0.969 0.83,1.13 169 2146
210 Benign neoplasm of lip, oral cavity, and pharynx neoplasms Both 0.0631 0.952 0.904,1.0 1584 15798 0.05495 0.95 0.902,1.0 1557 15253
211 Benign neoplasm of other parts of digestive system neoplasms Both 0.6026 0.993 0.965,1.02 5807 30296 0.3945 0.987 0.959,1.02 5361 30296
212 Benign neoplasm of respiratory and intrathoracic organs neoplasms Both 0.6561 1.01 0.96,1.07 1556 15533 0.5383 1.02 0.964,1.07 1517 14974
213 Benign neoplasm of bone and articular cartilage neoplasms Both 0.3483 0.974 0.922,1.03 1405 13304 0.2871 0.97 0.918,1.03 1371 13058
214 Lipoma neoplasms Both 0.873 0.995 0.936,1.06 1117 11124 0.6637 0.982 0.907,1.06 658 6580
214.1 Lipoma of skin and subcutaneous tissue neoplasms Both 0.597 0.979 0.905,1.06 681 6793 0.6637 0.982 0.907,1.06 658 6580
215 Other benign neoplasm of connective and other soft tissue neoplasms Both 0.2512 0.98 0.947,1.01 3594 32904 0.1225 0.973 0.939,1.01 3446 31894
216 Benign neoplasm of skin neoplasms Both 0.6577 0.995 0.971,1.02 9073 29036 0.06026 0.831 0.685,1.01 105 1062
216.1 Screening for malignant neoplasms of the skin neoplasms Both 0.07244 0.842 0.697,1.02 111 1093 0.06026 0.831 0.685,1.01 105 1062
217 Vascular hamartomas and non-neoplastic nevi neoplasms Both 0.3681 0.973 0.916,1.03 1150 11417 0.5284 0.98 0.919,1.04 1018 10218
217.1 Nevus, non-neoplastic neoplasms Both 0.4667 0.977 0.918,1.04 1063 10579 0.5284 0.98 0.919,1.04 1018 10218
218 Benign neoplasm of uterus neoplasms Female 0.7516 0.994 0.958,1.03 3552 13845 0.975 0.999 0.959,1.04 2740 13415
218.1 Uterine leiomyoma neoplasms Female 0.4074 0.978 0.927,1.03 1506 13465 0.3126 0.972 0.921,1.03 1451 13174
218.2 Other benign neoplasm of uterus neoplasms Female 0.929 0.998 0.958,1.04 2824 13698 0.975 0.999 0.959,1.04 2740 13415
220 Benign neoplasm of ovary neoplasms Female 0.1641 1.05 0.978,1.14 763 7571 0.1722 1.06 0.977,1.14 726 7410
221 Benign neoplasm of other female genital organs neoplasms Female 0.1125 1.04 0.99,1.1 1666 12074 0.0955 1.05 0.992,1.1 1583 11826
222 Benign neoplasm of male genital organs neoplasms Male 0.9594 0.998 0.934,1.07 954 9116 0.9661 0.999 0.933,1.07 924 8739
223 Benign neoplasm of kidney and other urinary organs neoplasms Both 0.8531 0.995 0.943,1.05 1547 11080 0.7762 0.992 0.939,1.05 1473 10844
224 Benign neoplasm of eye neoplasms Both 0.02042 1.11 1.02,1.22 511 5062 0.003162 1.17 1.05,1.29 406 4061
224.1 Benign neoplasm of eye, uveal neoplasms Both 0.008318 1.14 1.04,1.26 429 4230 0.003162 1.17 1.05,1.29 406 4061
225 Benign neoplasm of brain and other parts of nervous system neoplasms Both 0.8318 0.993 0.932,1.06 1039 10379 0.4477 1.05 0.921,1.21 235 2326
225.1 Benign neoplasm of brain, cranial nerves, meninges neoplasms Both 0.6592 0.984 0.917,1.06 817 8160 0.811 0.991 0.922,1.07 795 7874
225.2 Benign neoplasm of spinal cord, meninges neoplasms Both 0.5 1.05 0.916,1.2 242 2420 0.4477 1.05 0.921,1.21 235 2326
226 Benign neoplasm of thyroid glands neoplasms Both 0.984 0.999 0.939,1.06 1082 10810 0.9863 0.999 0.938,1.06 1055 10468
227 Benign neoplasm of other endocrine glands and related structures neoplasms Both 0.5272 0.982 0.93,1.04 1387 13870 0.7413 0.982 0.883,1.09 368 3604
227.1 Benign neoplasm of adrenal gland neoplasms Both 0.3467 0.95 0.853,1.06 375 3745 0.3614 0.951 0.853,1.06 364 3602
227.2 Benign neoplasm of parathyroid gland neoplasms Both 0.4093 0.967 0.892,1.05 644 6434 0.4083 0.966 0.891,1.05 633 6222
227.3 Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch) neoplasms Both 0.8147 0.987 0.888,1.1 373 3724 0.7413 0.982 0.883,1.09 368 3604
228 Hemangioma and lymphangioma, any site neoplasms Both 0.1871 0.965 0.915,1.02 1517 15150 0.04786 0.93 0.865,0.999 806 8156
228.1 Hemangioma of skin and subcutaneous tissue neoplasms Both 0.0389 0.928 0.865,0.996 849 8478 0.04786 0.93 0.865,0.999 806 8156
229 Benign neoplasm of unspecified sites neoplasms Both 0.9484 1.0 0.975,1.03 6631 31223 0.3936 1.01 0.983,1.05 4666 28846
229.1 Benign neoplasm of lymph nodes neoplasms Both 0.4753 1.01 0.981,1.04 4904 29712 0.3936 1.01 0.983,1.05 4666 28846
860 Bone marrow or stem cell transplant neoplasms Both 0.695 0.965 0.807,1.15 127 1266 0.7328 0.969 0.808,1.16 121 1227
240 Simple and unspecified goiter endocrine/metabolic Both 0.4335 1.03 0.956,1.11 767 7647 0.7063 1.01 0.94,1.1 734 7399
241 Nontoxic nodular goiter endocrine/metabolic Both 0.7047 0.992 0.949,1.04 2274 18240 0.8356 0.993 0.93,1.06 984 9730
241.1 Nontoxic uninodular goiter endocrine/metabolic Both 0.8054 0.994 0.947,1.04 1795 16440 0.3864 0.978 0.931,1.03 1727 15905
241.2 Nontoxic multinodular goiter endocrine/metabolic Both 0.9247 1.0 0.94,1.07 1017 10065 0.8356 0.993 0.93,1.06 984 9730
242 Thyrotoxicosis with or without goiter endocrine/metabolic Both 0.002692 1.1 1.03,1.17 1075 10635 0.9333 0.992 0.819,1.2 115 1116
242.1 Graves' disease endocrine/metabolic Both 0.6871 1.02 0.92,1.13 399 3965 0.877 1.01 0.907,1.12 389 3858
242.2 Toxic multinodular goiter endocrine/metabolic Both 0.1884 1.15 0.935,1.41 98 978 0.2042 1.14 0.929,1.41 96 936
242.3 Exophthalmos endocrine/metabolic Both 0.3758 1.06 0.931,1.21 245 2447 0.9333 0.992 0.819,1.2 115 1116
242.31 Thyrotoxic exophthalmos endocrine/metabolic Both 0.9705 1.0 0.83,1.21 116 1160 0.9333 0.992 0.819,1.2 115 1116
244 Hypothyroidism endocrine/metabolic Both 0.4111 1.01 0.984,1.04 6448 27183 0.5585 1.01 0.98,1.04 5789 25859
244.1 Secondary hypothyroidism endocrine/metabolic Both 0.2323 1.03 0.979,1.09 1421 14153 0.3656 1.03 0.971,1.08 1387 13713
244.2 Acquired hypothyroidism endocrine/metabolic Both 0.1122 1.06 0.987,1.14 853 8502 0.134 1.06 0.983,1.13 820 8242
244.4 Hypothyroidism NOS endocrine/metabolic Both 0.3715 1.01 0.984,1.04 5996 26719 0.5585 1.01 0.98,1.04 5789 25859
245 Thyroiditis endocrine/metabolic Both 0.04898 1.09 1.0,1.19 574 5720 0.1452 1.07 0.975,1.18 444 4397
245.2 Chronic thyroiditis endocrine/metabolic Both 0.1585 1.07 0.974,1.18 463 4617 0.1452 1.07 0.975,1.18 444 4397
245.21 Chronic lymphocytic thyroiditis endocrine/metabolic Both 0.1445 1.07 0.976,1.18 456 4533 0.1452 1.07 0.975,1.18 444 4397
246 Other disorders of thyroid endocrine/metabolic Both 0.06607 1.03 0.998,1.06 5018 25158 0.7709 0.987 0.903,1.08 550 5485
246.2 Thyroid cyst endocrine/metabolic Both 0.4624 1.09 0.865,1.38 83 804 0.8166 1.03 0.81,1.31 81 777
246.7 Abnormal results of function study of thyroid endocrine/metabolic Both 0.7096 0.984 0.902,1.07 568 5651 0.7709 0.987 0.903,1.08 550 5485
249 Secondary diabetes mellitus endocrine/metabolic Both 0.02042 0.911 0.842,0.986 686 6849 0.05248 0.923 0.851,1.0 655 6617
250 Diabetes mellitus endocrine/metabolic Both 0.857 0.998 0.975,1.02 10115 27568 0.9354 0.997 0.926,1.07 788 7897
250.1 Type 1 diabetes endocrine/metabolic Both 0.1486 0.954 0.896,1.02 1053 10521 0.9419 0.991 0.77,1.27 67 672
250.11 Type 1 diabetes with ketoacidosis endocrine/metabolic Both 0.2576 1.15 0.905,1.45 80 792 0.1574 1.19 0.935,1.52 76 777
250.12 Type 1 diabetes with renal manifestations endocrine/metabolic Both 0.6823 1.03 0.901,1.17 235 2346 0.5649 1.04 0.909,1.19 222 2277
250.13 Type 1 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.6745 0.974 0.863,1.1 280 2800 0.873 1.01 0.892,1.14 267 2717
250.14 Type 1 diabetes with neurological manifestations endocrine/metabolic Both 0.7413 0.978 0.857,1.12 238 2372 0.9683 1.0 0.876,1.15 227 2307
250.15 Diabetes type 1 with peripheral circulatory disorders endocrine/metabolic Both 0.4102 0.902 0.707,1.15 70 690 0.9419 0.991 0.77,1.27 67 672
250.2 Type 2 diabetes endocrine/metabolic Both 0.3936 0.988 0.962,1.02 7035 26169 0.826 1.01 0.92,1.11 479 4891
250.21 Type 2 diabetes with ketoacidosis endocrine/metabolic Both 0.1486 0.868 0.717,1.05 120 1200 0.1919 0.878 0.723,1.07 116 1160
250.22 Type 2 diabetes with renal manifestations endocrine/metabolic Both 0.354 0.971 0.914,1.03 1133 11056 0.5984 0.983 0.923,1.05 1067 10659
250.23 Type 2 diabetes with ophthalmic manifestations endocrine/metabolic Both 0.9638 0.998 0.929,1.07 826 8208 0.7145 1.01 0.942,1.09 796 7939
250.24 Type 2 diabetes with neurological manifestations endocrine/metabolic Both 0.6607 0.988 0.935,1.04 1419 13969 0.8299 0.994 0.94,1.05 1337 13469
250.25 Diabetes type 2 with peripheral circulatory disorders endocrine/metabolic Both 0.6761 1.02 0.932,1.12 513 5077 0.826 1.01 0.92,1.11 479 4891
250.3 Insulin pump user endocrine/metabolic Both 0.1324 0.964 0.92,1.01 1884 17814 0.1368 0.964 0.918,1.01 1766 17218
250.4 Abnormal glucose endocrine/metabolic Both 0.811 0.996 0.967,1.03 5404 26451 0.7228 1.01 0.974,1.04 4526 25130
250.41 Impaired fasting glucose endocrine/metabolic Both 0.8222 0.994 0.939,1.05 1326 13130 0.8375 0.994 0.938,1.05 1269 12683
250.42 Other abnormal glucose endocrine/metabolic Both 0.9683 1.0 0.97,1.03 4736 25883 0.7228 1.01 0.974,1.04 4526 25130
250.5 Glycosuria or Acetonuria endocrine/metabolic Both 0.7943 1.03 0.814,1.31 78 747 0.7295 1.04 0.821,1.33 76 729
250.6 Polyneuropathy in diabetes endocrine/metabolic Both 0.879 0.995 0.937,1.06 1137 11335 0.9247 1.0 0.942,1.07 1067 10933
250.7 Diabetic retinopathy endocrine/metabolic Both 0.6486 0.983 0.915,1.06 821 8168 0.9354 0.997 0.926,1.07 788 7897
251 Other disorders of pancreatic internal secretion endocrine/metabolic Both 0.2767 1.05 0.963,1.14 595 5901 0.4487 1.03 0.952,1.12 662 6818
251.1 Hypoglycemia endocrine/metabolic Both 0.526 1.03 0.948,1.11 702 7015 0.4487 1.03 0.952,1.12 662 6818
252 Disorders of parathyroid gland endocrine/metabolic Both 0.6577 0.989 0.943,1.04 1807 17879 0.3954 0.956 0.862,1.06 385 3824
252.1 Hyperparathyroidism endocrine/metabolic Both 0.6353 0.988 0.939,1.04 1656 16459 0.6855 0.989 0.94,1.04 1594 15912
252.2 Hypoparathyroidism endocrine/metabolic Both 0.414 0.958 0.865,1.06 393 3922 0.3954 0.956 0.862,1.06 385 3824
253 Disorders of the pituitary gland and its hypothalamic control endocrine/metabolic Both 0.8375 1.01 0.933,1.09 691 6893 0.9817 0.998 0.804,1.24 83 895
253.1 Pituitary hyperfunction endocrine/metabolic Both 0.561 0.958 0.829,1.11 205 2041 0.6966 0.956 0.76,1.2 72 701
253.11 Acromegaly and gigantism endocrine/metabolic Both 0.6808 0.953 0.758,1.2 72 720 0.6966 0.956 0.76,1.2 72 701
253.2 Pituitary hypofunction endocrine/metabolic Both 0.4295 1.06 0.915,1.23 184 1840 0.4198 1.06 0.915,1.24 183 1790
253.3 Diabetes insipidus endocrine/metabolic Both 0.52 1.08 0.857,1.36 70 694 0.4887 1.09 0.861,1.37 67 674
253.4 Anterior pituitary disorders endocrine/metabolic Both 0.3126 1.12 0.9,1.39 92 899 0.3155 1.12 0.898,1.39 89 868
253.7 Other disorders of neurohypophysis endocrine/metabolic Both 0.9419 1.01 0.82,1.24 93 925 0.9817 0.998 0.804,1.24 83 895
255 Disorders of adrenal glands endocrine/metabolic Both 0.03236 0.937 0.882,0.995 1186 11860 0.03981 0.902 0.817,0.995 438 4340
255.1 Adrenal hyperfunction endocrine/metabolic Both 0.4111 0.951 0.844,1.07 290 2886 0.2234 0.883 0.722,1.08 100 1033
255.11 Cushing's syndrome endocrine/metabolic Both 0.955 1.0 0.846,1.19 144 1440 0.9886 1.0 0.84,1.19 140 1391
255.12 Hyperaldosteronism endocrine/metabolic Both 0.3221 0.906 0.744,1.1 106 1057 0.2234 0.883 0.722,1.08 100 1033
255.2 Adrenal hypofunction endocrine/metabolic Both 0.06026 0.914 0.832,1.0 477 4758 0.03981 0.902 0.817,0.995 438 4340
255.21 Glucocorticoid deficiency endocrine/metabolic Both 0.05623 0.909 0.825,1.0 451 4496 0.03981 0.902 0.817,0.995 438 4340
256 Ovarian dysfunction endocrine/metabolic Female 0.5346 0.978 0.911,1.05 859 8184 0.7278 0.984 0.899,1.08 535 5359
256.4 Polycystic ovaries endocrine/metabolic Female 0.929 0.996 0.911,1.09 544 5436 0.7278 0.984 0.899,1.08 535 5359
257 Testicular dysfunction endocrine/metabolic Male 0.7745 0.989 0.916,1.07 747 7455 0.6237 0.98 0.906,1.06 692 6949
257.1 Testicular hypofunction endocrine/metabolic Male 0.8091 0.991 0.917,1.07 725 7234 0.6237 0.98 0.906,1.06 692 6949
258 Iatrogenic endocrine disorders endocrine/metabolic Both 0.6918 1.05 0.827,1.33 66 660 0.6622 0.953 0.768,1.18 91 901
258.1 Postablative ovarian failure endocrine/metabolic Female 0.7145 0.961 0.775,1.19 92 920 0.6622 0.953 0.768,1.18 91 901
259 Other endocrine disorders endocrine/metabolic Both 0.5702 1.02 0.949,1.1 759 7562 0.52 1.03 0.95,1.11 728 7338
260 Protein-calorie malnutrition endocrine/metabolic Both 0.4064 0.982 0.941,1.02 2353 22279 0.3041 0.958 0.882,1.04 618 6531
260.1 Cachexia endocrine/metabolic Both 0.8185 0.985 0.862,1.12 239 2388 0.7328 0.976 0.848,1.12 211 2320
260.2 severe protein-calorie malnutrition endocrine/metabolic Both 0.4093 0.977 0.924,1.03 1363 13589 0.4819 0.962 0.864,1.07 365 3999
260.22 Nutritional marasmus endocrine/metabolic Both 0.881 0.992 0.896,1.1 413 4130 0.4819 0.962 0.864,1.07 365 3999
260.3 Adult failure to thrive endocrine/metabolic Both 0.271 0.949 0.865,1.04 509 5051 0.1892 0.937 0.851,1.03 462 4900
260.6 Anorexia endocrine/metabolic Both 0.2917 0.959 0.886,1.04 677 6722 0.3041 0.958 0.882,1.04 618 6531
261 Vitamin deficiency endocrine/metabolic Both 0.5309 0.991 0.963,1.02 5614 30157 0.3327 0.985 0.956,1.02 5025 29130
261.2 Vitamin B-complex deficiencies endocrine/metabolic Both 0.241 1.05 0.968,1.14 649 6482 0.4335 1.03 0.951,1.12 606 6291
261.4 Vitamin D deficiency endocrine/metabolic Both 0.4246 0.988 0.959,1.02 5264 29859 0.3327 0.985 0.956,1.02 5025 29130
262 Mineral deficiency NEC endocrine/metabolic Both 0.7962 0.991 0.924,1.06 854 8532 0.9419 0.997 0.928,1.07 806 8303
263 Other nutritional deficiency endocrine/metabolic Both 0.6053 0.973 0.879,1.08 412 4113 0.3396 0.95 0.856,1.05 392 4017
264 Lack of normal physiological development endocrine/metabolic Both 0.07943 0.869 0.742,1.02 175 1735 0.173 0.824 0.623,1.09 58 599
264.2 Failure to thrive (childhood) endocrine/metabolic Both 0.673 0.955 0.772,1.18 95 950 0.8414 0.978 0.786,1.22 90 921
264.9 Lack of normal physiological development, unspecified endocrine/metabolic Both 0.2553 0.854 0.65,1.12 61 607 0.173 0.824 0.623,1.09 58 599
269 Proteinuria endocrine/metabolic Both 0.2606 0.965 0.907,1.03 1079 10768 0.375 0.971 0.911,1.04 1021 10415
270 Disorders of protein plasma/amino-acid transport and metabolism endocrine/metabolic Both 0.7328 0.987 0.915,1.06 740 7378 0.6166 1.04 0.897,1.2 203 2114
270.1 Disturbances of amino-acid transport endocrine/metabolic Both 0.2249 0.897 0.752,1.07 129 1283 0.2529 0.889 0.726,1.09 98 970
270.11 Disturbances of sulphur-bearing amino-acid metabolism endocrine/metabolic Both 0.2661 0.892 0.73,1.09 101 998 0.2529 0.889 0.726,1.09 98 970
270.2 Disorders of amino-acid metabolism endocrine/metabolic Both 0.9354 0.991 0.801,1.23 81 810 0.9204 1.01 0.815,1.25 79 781
270.3 Disorders of plasma protein metabolism endocrine/metabolic Both 0.8279 1.01 0.925,1.1 560 5581 0.6166 1.04 0.897,1.2 203 2114
270.32 Paraproteinemia endocrine/metabolic Both 0.8453 1.01 0.897,1.14 301 2982 0.5284 1.04 0.919,1.18 285 2869
270.33 Amyloidosis endocrine/metabolic Both 0.4624 1.12 0.834,1.49 55 550 0.3289 1.16 0.86,1.57 52 530
270.38 Other specified disorders of plasma protein metabolism endocrine/metabolic Both 0.6194 1.04 0.901,1.19 218 2178 0.6166 1.04 0.897,1.2 203 2114
271 Disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.05623 1.05 0.999,1.1 1952 19491 0.7656 1.03 0.826,1.3 81 793
271.3 Intestinal disaccharidase deficiencies and disaccharide malabsorption endocrine/metabolic Both 0.06918 1.04 0.996,1.1 1885 18823 0.06607 1.05 0.997,1.1 1804 18180
271.9 Other disorders of carbohydrate transport and metabolism endocrine/metabolic Both 0.7925 1.03 0.823,1.29 81 810 0.7656 1.03 0.826,1.3 81 793
272 Disorders of lipoid metabolism endocrine/metabolic Both 0.005623 0.969 0.947,0.991 14793 22696 0.1194 0.899 0.786,1.03 228 2332
272.1 Hyperlipidemia endocrine/metabolic Both 0.004898 0.968 0.947,0.99 14763 22682 0.05248 0.956 0.913,1.0 2168 14963
272.11 Hypercholesterolemia endocrine/metabolic Both 0.04467 0.966 0.935,0.999 4668 18640 0.1052 0.972 0.94,1.01 4464 18068
272.12 Hyperglyceridemia endocrine/metabolic Both 0.1419 0.951 0.89,1.02 945 9395 0.2239 0.958 0.895,1.03 895 9106
272.13 Mixed hyperlipidemia endocrine/metabolic Both 0.02692 0.951 0.91,0.994 2272 15492 0.05248 0.956 0.913,1.0 2168 14963
272.9 Unspecified disorder of lipoid metabolism endocrine/metabolic Both 0.0537 0.88 0.773,1.0 244 2425 0.1194 0.899 0.786,1.03 228 2332
274 Gout and other crystal arthropathies endocrine/metabolic Both 0.8318 0.995 0.95,1.04 1971 18337 0.455 1.07 0.896,1.28 131 1303
274.1 Gout endocrine/metabolic Both 0.7211 0.991 0.945,1.04 1879 17712 0.5754 0.979 0.909,1.05 762 7592
274.11 Gouty arthropathy endocrine/metabolic Both 0.7244 0.987 0.918,1.06 793 7891 0.5754 0.979 0.909,1.05 762 7592
274.2 Crystal arthropathies endocrine/metabolic Both 0.2884 1.1 0.925,1.3 146 1425 0.455 1.07 0.896,1.28 131 1303
274.21 Chondrocalcinosis endocrine/metabolic Both 0.3184 1.09 0.919,1.3 140 1363 0.455 1.07 0.896,1.28 131 1303
275 Disorders of mineral metabolism endocrine/metabolic Both 0.2489 0.979 0.944,1.02 3252 30253 0.3381 1.13 0.881,1.44 68 677
275.3 Disorders of magnesium metabolism endocrine/metabolic Both 0.7834 0.99 0.923,1.06 845 8441 0.9354 0.997 0.927,1.07 785 8161
275.5 Disorders of calcium/phosphorus metabolism endocrine/metabolic Both 0.1849 0.973 0.934,1.01 2502 24757 0.7852 0.991 0.926,1.06 926 9844
275.51 Hypocalcemia endocrine/metabolic Both 0.8892 1.01 0.931,1.09 722 7203 0.8185 1.01 0.933,1.09 687 6998
275.53 Disorders of phosphorus metabolism endocrine/metabolic Both 0.8222 0.993 0.931,1.06 1024 10193 0.7852 0.991 0.926,1.06 926 9844
275.6 Hypercalcemia endocrine/metabolic Both 0.1795 0.957 0.899,1.02 1043 10415 0.2168 0.96 0.9,1.02 1005 10071
276 Disorders of fluid, electrolyte, and acid-base balance endocrine/metabolic Both 0.7834 0.996 0.971,1.02 7227 30901 0.06457 1.21 0.989,1.49 96 965
276.1 Electrolyte imbalance endocrine/metabolic Both 0.6622 0.993 0.963,1.02 4833 28673 0.6561 0.988 0.937,1.04 1502 15713
276.11 Hyperosmolality and/or hypernatremia endocrine/metabolic Both 0.9638 1.0 0.906,1.11 415 4115 0.9311 0.995 0.896,1.11 384 3994
276.12 Hyposmolality and/or hyponatremia endocrine/metabolic Both 0.4159 0.98 0.935,1.03 1857 17982 0.1919 0.968 0.921,1.02 1733 17424
276.13 Hyperpotassemia endocrine/metabolic Both 0.5623 0.987 0.945,1.03 2238 20576 0.5649 0.987 0.943,1.03 2101 19962
276.14 Hypopotassemia endocrine/metabolic Both 0.8414 0.995 0.946,1.05 1626 16160 0.6561 0.988 0.937,1.04 1502 15713
276.4 Acid-base balance disorder endocrine/metabolic Both 0.3963 1.02 0.971,1.08 1593 15855 0.4285 1.05 0.936,1.17 325 3408
276.41 Acidosis endocrine/metabolic Both 0.526 1.02 0.963,1.08 1357 13508 0.6699 1.01 0.956,1.07 1261 13121
276.42 Alkalosis endocrine/metabolic Both 0.3214 1.06 0.948,1.18 350 3498 0.4285 1.05 0.936,1.17 325 3408
276.5 Hypovolemia endocrine/metabolic Both 0.4446 1.01 0.979,1.05 3615 28901 0.507 1.01 0.976,1.05 3337 28183
276.6 Fluid overload endocrine/metabolic Both 0.5572 0.981 0.92,1.05 1046 10404 0.8453 0.994 0.931,1.06 999 10084
276.8 Polydipsia endocrine/metabolic Both 0.07079 1.21 0.984,1.48 99 990 0.06457 1.21 0.989,1.49 96 965
277 Other disorders of metabolism endocrine/metabolic Both 0.2023 0.966 0.917,1.02 1534 15324 0.7998 1.01 0.929,1.1 593 5891
277.2 Other disorders of purine and pyrimidine metabolism endocrine/metabolic Both 0.7907 0.982 0.862,1.12 252 2520 0.8531 0.987 0.864,1.13 236 2425
277.4 Disorders of bilirubin excretion endocrine/metabolic Both 0.2254 1.06 0.967,1.15 547 5456 0.2388 1.06 0.964,1.16 502 5262
277.5 Other disorders of lipoid metabolism endocrine/metabolic Both 0.01148 0.903 0.835,0.977 675 6743 0.02455 0.905 0.829,0.987 548 5496
277.51 Lipoprotein disorders endocrine/metabolic Both 0.01479 0.899 0.825,0.979 567 5665 0.02455 0.905 0.829,0.987 548 5496
277.7 Dysmetabolic syndrome X endocrine/metabolic Both 0.9683 1.0 0.921,1.09 610 6090 0.7998 1.01 0.929,1.1 593 5891
278 Overweight, obesity and other hyperalimentation endocrine/metabolic Both 0.2931 1.01 0.991,1.03 15130 23191 0.4853 0.981 0.929,1.04 1468 13354
278.1 Obesity endocrine/metabolic Both 0.1936 1.01 0.993,1.04 13507 23193 0.4285 1.01 0.983,1.04 6147 22520
278.11 Morbid obesity endocrine/metabolic Both 0.4256 1.01 0.984,1.04 6376 23143 0.4285 1.01 0.983,1.04 6147 22520
278.3 Localized adiposity endocrine/metabolic Both 0.1021 0.901 0.796,1.02 270 2694 0.08913 0.897 0.791,1.02 267 2627
278.4 Abnormal weight gain endocrine/metabolic Both 0.6714 0.989 0.937,1.04 1522 13685 0.4853 0.981 0.929,1.04 1468 13354
279 Disorders involving the immune mechanism endocrine/metabolic Both 0.2128 0.973 0.932,1.02 2245 22393 0.4742 0.964 0.873,1.07 426 4283
279.1 Immunity deficiency endocrine/metabolic Both 0.6012 0.982 0.916,1.05 881 8792 0.1968 0.917 0.805,1.05 242 2466
279.11 Deficiency of humoral immunity endocrine/metabolic Both 0.1294 0.905 0.796,1.03 254 2540 0.1968 0.917 0.805,1.05 242 2466
279.2 Autoimmune disease NEC endocrine/metabolic Both 0.3802 0.962 0.884,1.05 574 5735 0.5297 0.973 0.892,1.06 554 5548
279.7 Other immunological findings endocrine/metabolic Both 0.3631 0.985 0.952,1.02 3927 30734 0.4624 0.987 0.954,1.02 3749 29796
279.8 Other specified disorders involving the immune mechanism endocrine/metabolic Both 0.4603 0.964 0.874,1.06 443 4423 0.4742 0.964 0.873,1.07 426 4283
275.1 Disorders of iron metabolism hematopoietic Both 0.8356 0.983 0.837,1.15 168 1680 0.3381 1.13 0.881,1.44 68 677
275.11 Hereditary hemochromatosis hematopoietic Both 0.415 1.11 0.867,1.41 70 700 0.3381 1.13 0.881,1.44 68 677
280 Iron deficiency anemias hematopoietic Both 0.227 1.02 0.987,1.06 3537 25593 0.2193 1.04 0.978,1.1 1249 13149
280.1 Iron deficiency anemias, unspecified or not due to blood loss hematopoietic Both 0.1849 1.02 0.988,1.06 3410 25349 0.1667 1.03 0.989,1.07 3163 24736
280.2 Iron deficiency anemia secondary to blood loss (chronic) hematopoietic Both 0.3581 1.03 0.971,1.09 1361 13511 0.2193 1.04 0.978,1.1 1249 13149
281 Other deficiency anemia hematopoietic Both 0.7816 1.01 0.913,1.13 387 3838 0.8299 0.984 0.853,1.14 203 2058
281.1 Megaloblastic anemia hematopoietic Both 0.6855 1.03 0.888,1.2 189 1875 0.5164 1.06 0.884,1.28 125 1301
281.11 Pernicious anemia hematopoietic Both 0.9528 1.01 0.807,1.26 84 830 0.9099 1.01 0.809,1.27 79 802
281.12 Other vitamin B12 deficiency anemia hematopoietic Both 0.5023 1.06 0.889,1.27 135 1348 0.5164 1.06 0.884,1.28 125 1301
281.9 Deficiency anemias hematopoietic Both 0.865 0.988 0.859,1.14 214 2110 0.8299 0.984 0.853,1.14 203 2058
282 Hereditary hemolytic anemias hematopoietic Both 0.6486 0.97 0.852,1.1 248 2443 0.6081 0.955 0.802,1.14 134 1386
282.8 Other hemoglobinopathies hematopoietic Both 0.8892 1.01 0.861,1.19 158 1541 0.8241 0.981 0.832,1.16 149 1497
282.9 Other hereditary hemolytic anemias hematopoietic Both 0.9204 0.991 0.836,1.18 143 1420 0.6081 0.955 0.802,1.14 134 1386
283 Acquired hemolytic anemias hematopoietic Both 0.2723 1.1 0.926,1.31 130 1295 0.369 1.09 0.907,1.3 123 1252
283.1 Autoimmune hemolytic anemias hematopoietic Both 0.861 0.976 0.74,1.29 54 532 ,
284 Aplastic anemia hematopoietic Both 0.6266 1.02 0.938,1.11 558 5545 0.5572 1.03 0.935,1.13 449 4722
284.1 Pancytopenia hematopoietic Both 0.5047 1.03 0.941,1.13 488 4847 0.5572 1.03 0.935,1.13 449 4722
285 Other anemias hematopoietic Both 0.8954 1.0 0.978,1.03 9426 28014 0.7261 1.02 0.928,1.11 494 5403
285.1 Acute posthemorrhagic anemia hematopoietic Both 0.1306 1.03 0.991,1.08 2536 22457 0.1355 1.03 0.99,1.08 2374 21860
285.2 Anemia of chronic disease hematopoietic Both 0.7295 1.01 0.958,1.06 1584 15823 0.7261 1.02 0.928,1.11 494 5403
285.21 Anemia in chronic kidney disease hematopoietic Both 0.6966 1.02 0.938,1.1 673 6722 0.8395 1.01 0.929,1.09 632 6533
285.22 Anemia in neoplastic disease hematopoietic Both 0.6339 1.02 0.937,1.11 555 5536 0.7261 1.02 0.928,1.11 494 5403
286 Coagulation defects hematopoietic Both 0.2443 1.02 0.985,1.06 3013 27144 0.7852 1.01 0.941,1.08 841 8454
286.1 Congenital coagulation defects hematopoietic Both 0.0955 1.13 0.978,1.31 190 1889 0.2897 1.12 0.905,1.4 90 947
286.11 Von willebrand's disease hematopoietic Both 0.5236 1.08 0.846,1.39 64 640 0.492 1.09 0.848,1.41 61 625
286.12 Congenital deficiency of other clotting factors (including factor VII) hematopoietic Both 0.1256 1.18 0.955,1.45 98 973 0.2897 1.12 0.905,1.4 90 947
286.2 Encounter for long-term (current) use of anticoagulants hematopoietic Both 0.9354 0.998 0.958,1.04 2601 20964 0.9795 1.0 0.959,1.04 2447 20292
286.3 Coagulation defects complicating pregnancy or postpartum hematopoietic Female 0.6592 1.06 0.812,1.39 60 590 0.6839 1.06 0.807,1.39 58 584
286.4 Acquired coagulation factor deficiency hematopoietic Both 0.6427 0.964 0.827,1.12 186 1860 0.6081 0.959 0.819,1.12 174 1798
286.5 Hemorrhagic disorder due to intrinsic circulating anticoagulants hematopoietic Both 0.2897 1.12 0.906,1.39 92 906 0.3048 1.12 0.901,1.39 88 879
286.6 Defibrination syndrome hematopoietic Both 0.3148 1.02 0.978,1.07 1964 19522 0.5559 1.01 0.967,1.06 1852 18928
286.7 Other and unspecified coagulation defects hematopoietic Both 0.3083 1.02 0.98,1.07 2349 23153 0.4842 1.02 0.972,1.06 2220 22433
286.8 Hypercoagulable state hematopoietic Both 0.8017 1.01 0.932,1.1 643 6420 0.7925 1.01 0.93,1.1 592 5996
286.81 Primary hypercoagulable state hematopoietic Both 0.7031 1.02 0.936,1.1 618 6179 0.7925 1.01 0.93,1.1 592 5996
286.9 Abnormal coagulation profile hematopoietic Both 0.9462 1.0 0.936,1.07 890 8770 0.7852 1.01 0.941,1.08 841 8454
287 Purpura and other hemorrhagic conditions hematopoietic Both 0.8995 0.997 0.958,1.04 2575 22699 0.3784 0.901 0.715,1.14 72 730
287.1 Spontaneous ecchymoses hematopoietic Both 0.4436 0.938 0.797,1.1 154 1532 0.4864 0.942 0.798,1.11 147 1482
287.3 Thrombocytopenia hematopoietic Both 0.4018 0.982 0.94,1.02 2297 20909 0.1538 0.928 0.837,1.03 397 4201
287.31 Primary thrombocytopenia hematopoietic Both 0.7079 0.982 0.892,1.08 481 4785 0.7603 0.985 0.893,1.09 463 4632
287.32 Secondary thrombocytopenia hematopoietic Both 0.1122 0.923 0.836,1.02 436 4360 0.1538 0.928 0.837,1.03 397 4201
287.4 Qualitative platelet defects hematopoietic Both 0.52 0.928 0.738,1.17 76 760 0.3784 0.901 0.715,1.14 72 730
288 Diseases of white blood cells hematopoietic Both 0.9099 0.998 0.965,1.03 3850 30383 0.6026 1.05 0.872,1.27 125 1246
288.1 Decreased white blood cell count hematopoietic Both 0.6823 0.988 0.932,1.05 1252 12520 0.3508 0.966 0.9,1.04 811 8726
288.11 Neutropenia hematopoietic Both 0.5408 0.979 0.914,1.05 896 8960 0.3508 0.966 0.9,1.04 811 8726
288.2 Elevated white blood cell count hematopoietic Both 0.865 1.0 0.967,1.04 3179 28632 0.9616 0.999 0.962,1.04 2984 27885
288.3 Eosinophilia hematopoietic Both 0.5445 1.06 0.88,1.27 128 1278 0.6026 1.05 0.872,1.27 125 1246
289 Other diseases of blood and blood-forming organs hematopoietic Both 0.7464 0.99 0.935,1.05 1259 12554 0.8128 1.02 0.897,1.15 260 2683
289.3 Personal history of diseases of blood and blood-forming organs hematopoietic Both 0.5035 0.972 0.894,1.06 615 6123 0.4121 0.965 0.886,1.05 588 5983
289.4 Lymphadenitis hematopoietic Both 0.4436 1.01 0.978,1.05 3186 28420 0.5728 1.01 0.974,1.05 2989 27688
289.5 Diseases of spleen hematopoietic Both 0.8204 1.01 0.901,1.14 313 3130 0.4335 1.05 0.93,1.18 294 3053
289.8 Polycythemia, secondary hematopoietic Both 0.4315 1.06 0.913,1.24 182 1820 0.6486 1.04 0.888,1.21 172 1770
289.9 Abnormality of red blood cells hematopoietic Both 0.8913 1.01 0.894,1.14 281 2776 0.8128 1.02 0.897,1.15 260 2683
290 Delirium dementia and amnestic and other cognitive disorders mental disorders Both 0.4539 0.976 0.915,1.04 1040 9399 0.1 0.933 0.859,1.01 619 6122
290.1 Dementias mental disorders Both 0.9078 1.01 0.908,1.11 407 3816 0.9528 0.996 0.872,1.14 242 2280
290.11 Alzheimer's disease mental disorders Both 0.3954 0.916 0.748,1.12 104 984 0.5188 0.933 0.754,1.15 95 931
290.12 Dementia with cerebral degenerations mental disorders Both 0.3105 1.13 0.891,1.44 71 705 0.5623 1.08 0.84,1.38 68 676
290.13 Senile dementia mental disorders Both 0.929 1.01 0.884,1.14 257 2376 0.9528 0.996 0.872,1.14 242 2280
290.16 Vascular dementia mental disorders Both 0.5321 1.1 0.823,1.46 53 508 ,
290.2 Delirium due to conditions classified elsewhere mental disorders Both 0.4236 0.967 0.89,1.05 634 6242 0.4487 0.968 0.889,1.05 600 6007
290.3 Other persistent mental disorders due to conditions classified elsewhere mental disorders Both 0.0871 0.932 0.859,1.01 642 6369 0.1 0.933 0.859,1.01 619 6122
291 Other specified nonpsychotic and/or transient mental disorders mental disorders Both 0.4819 0.984 0.939,1.03 1977 19673 0.5794 0.985 0.934,1.04 1505 14970
291.1 Transient mental disorders due to conditions classified elsewhere mental disorders Both 0.8831 1.01 0.858,1.19 161 1610 0.7603 1.03 0.868,1.21 158 1575
291.4 Specific nonpsychotic mental disorders due to brain damage mental disorders Both 0.2404 1.07 0.958,1.19 364 3634 0.1585 1.08 0.97,1.21 354 3518
291.8 Alteration of consciousness mental disorders Both 0.3119 0.974 0.924,1.03 1563 15497 0.5794 0.985 0.934,1.04 1505 14970
292 Neurological disorders mental disorders Both 0.4457 1.01 0.981,1.05 4340 31695 0.9594 0.995 0.837,1.18 137 1383
292.1 Aphasia/speech disturbance mental disorders Both 0.1807 1.04 0.984,1.09 1554 15459 0.3614 1.08 0.915,1.27 156 1559
292.11 Aphasia mental disorders Both 0.007762 1.13 1.03,1.24 516 5142 0.00871 1.13 1.03,1.24 497 4962
292.12 Symbolic dysfunction mental disorders Both 0.4808 1.06 0.901,1.25 162 1620 0.3614 1.08 0.915,1.27 156 1559
292.2 Mild cognitive impairment mental disorders Both 0.6039 1.03 0.914,1.17 276 2716 0.7345 1.02 0.901,1.16 263 2613
292.3 Memory loss mental disorders Both 0.2547 0.969 0.917,1.02 1405 13752 0.3404 0.973 0.92,1.03 1359 13242
292.4 Altered mental status mental disorders Both 0.8091 1.01 0.959,1.05 1885 18096 0.7278 1.01 0.961,1.06 1775 17445
292.5 Transient alteration of awareness mental disorders Both 0.3981 1.05 0.938,1.17 327 3237 0.2972 1.06 0.948,1.19 316 3138
292.6 Hallucinations mental disorders Both 0.9506 1.01 0.848,1.19 144 1429 0.9594 0.995 0.837,1.18 137 1383
293 Symptoms involving head and neck mental disorders Both 0.5152 0.962 0.856,1.08 304 3036 0.5781 0.99 0.957,1.03 3577 31374
293.1 Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS] mental disorders Both 0.7638 0.995 0.962,1.03 3691 32427 0.5781 0.99 0.957,1.03 3577 31374
295 Schizophrenia and other psychotic disorders mental disorders Both 0.1778 0.946 0.874,1.03 664 6564 0.1445 0.934 0.851,1.02 494 5036
295.1 Schizophrenia mental disorders Both 0.7603 0.97 0.8,1.18 111 1080 0.743 0.968 0.794,1.18 106 1052
295.2 Paranoid disorders mental disorders Both 0.8072 1.03 0.826,1.28 86 856 0.9572 0.994 0.794,1.24 81 824
295.3 Psychosis mental disorders Both 0.1493 0.936 0.856,1.02 527 5206 0.1445 0.934 0.851,1.02 494 5036
296 Mood disorders mental disorders Both 0.2698 0.987 0.964,1.01 12028 17942 0.3508 0.988 0.964,1.01 10401 17449
296.1 Bipolar mental disorders Both 0.471 1.02 0.959,1.09 994 9331 0.5572 1.02 0.955,1.09 969 9117
296.2 Depression mental disorders Both 0.2594 0.986 0.963,1.01 11641 17941 0.3508 0.988 0.964,1.01 10401 17449
296.22 Major depressive disorder mental disorders Both 0.3148 0.988 0.964,1.01 10773 17942 0.3508 0.988 0.964,1.01 10401 17449
297 Suicidal ideation or attempt mental disorders Both 0.4036 1.03 0.956,1.12 696 6932 0.4074 1.06 0.92,1.23 197 1976
297.1 Suicidal ideation mental disorders Both 0.857 0.992 0.909,1.08 559 5575 0.873 0.993 0.908,1.09 536 5454
297.2 Suicide or self-inflicted injury mental disorders Both 0.6039 1.04 0.901,1.2 201 2010 0.4074 1.06 0.92,1.23 197 1976
300 Anxiety disorders mental disorders Both 0.1726 0.984 0.961,1.01 12038 17949 0.02818 1.1 1.01,1.2 595 5981
300.1 Anxiety disorder mental disorders Both 0.2553 0.986 0.963,1.01 11352 17942 0.9817 0.999 0.925,1.08 714 7046
300.11 Generalized anxiety disorder mental disorders Both 0.3236 0.983 0.951,1.02 4496 17788 0.4236 0.986 0.953,1.02 4354 17295
300.12 Agorophobia, social phobia, and panic disorder mental disorders Both 0.9204 0.997 0.932,1.07 957 9152 0.9817 1.0 0.935,1.07 921 8932
300.13 Phobia mental disorders Both 0.9268 0.996 0.923,1.08 731 7231 0.9817 0.999 0.925,1.08 714 7046
300.3 Obsessive-compulsive disorders mental disorders Both 0.1517 1.1 0.965,1.26 223 2230 0.1816 1.1 0.958,1.26 219 2179
300.4 Dysthymic disorder mental disorders Both 0.2884 0.973 0.926,1.02 1798 13630 0.4285 0.98 0.931,1.03 1738 13267
300.8 Acute reaction to stress mental disorders Both 0.5333 1.04 0.928,1.15 359 3536 0.5047 1.04 0.93,1.16 349 3432
300.9 Posttraumatic stress disorder mental disorders Both 0.02188 1.1 1.01,1.2 612 6113 0.02818 1.1 1.01,1.2 595 5981
301 Personality disorders mental disorders Both 0.4093 1.05 0.939,1.17 363 3626 0.3864 0.933 0.798,1.09 183 1818
301.2 Antisocial/borderline personality disorder mental disorders Both 0.3381 0.927 0.794,1.08 187 1868 0.3864 0.933 0.798,1.09 183 1818
302 Sexual and gender identity disorders mental disorders Both 0.1476 1.06 0.978,1.16 608 6055 0.06457 1.12 0.993,1.25 313 3138
302.1 Decreased libido mental disorders Both 0.04169 1.13 1.0,1.26 325 3233 0.06457 1.12 0.993,1.25 313 3138
303 Psychogenic and somatoform disorders mental disorders Both 0.1023 1.06 0.989,1.13 1030 10064 0.08913 1.06 0.991,1.14 902 8896
303.1 Dissociative disorder mental disorders Both 0.7482 0.969 0.801,1.17 115 1144 0.5929 0.948 0.78,1.15 111 1108
303.3 Psychogenic disorder mental disorders Both 0.1694 1.05 0.978,1.14 736 7330 0.2582 1.07 0.954,1.19 328 3300
303.31 Gastrointestinal malfunction arising from mental factors mental disorders Both 0.3199 1.06 0.948,1.18 340 3376 0.2582 1.07 0.954,1.19 328 3300
303.4 Somatoform disorder mental disorders Both 0.0912 1.06 0.991,1.13 925 9106 0.08913 1.06 0.991,1.14 902 8896
304 Adjustment reaction mental disorders Both 0.4989 1.01 0.974,1.06 2840 17464 0.4009 1.02 0.977,1.06 2730 16973
305.2 Eating disorder mental disorders Both 0.8318 1.01 0.93,1.09 650 6500 0.9462 1.0 0.924,1.09 634 6338
306 Other mental disorder mental disorders Both 0.2891 1.03 0.973,1.1 1254 10907 0.05754 1.09 0.997,1.2 507 5098
306.1 Mental disorders durring/after pregnancy mental disorders Female 0.2818 0.944 0.85,1.05 418 2847 0.2773 0.943 0.849,1.05 415 2812
306.9 Tension headache mental disorders Both 0.0537 1.09 0.998,1.2 521 5210 0.05754 1.09 0.997,1.2 507 5098
312 Conduct disorders mental disorders Both 0.08128 1.14 0.984,1.33 189 1890 0.3837 1.13 0.854,1.51 53 519
312.3 Impulse control disorder mental disorders Both 0.3908 1.13 0.852,1.5 53 530 0.3837 1.13 0.854,1.51 53 519
313 Pervasive developmental disorders mental disorders Both 0.2495 0.965 0.908,1.03 1148 11078 0.1233 0.81 0.619,1.06 58 582
313.1 Attention deficit hyperactivity disorder mental disorders Both 0.2917 0.966 0.906,1.03 1012 9899 0.2748 0.964 0.904,1.03 992 9717
313.2 Tics and stuttering mental disorders Both 0.07762 0.787 0.603,1.03 60 593 0.1233 0.81 0.619,1.06 58 582
315 Develomental delays and disorders mental disorders Both 0.7161 0.981 0.888,1.09 401 3990 0.2951 0.923 0.795,1.07 176 1750
315.1 Learning disorder mental disorders Both 0.695 0.948 0.727,1.24 60 599 0.7328 0.954 0.731,1.25 59 591
315.2 Speech and language disorder mental disorders Both 0.4955 0.95 0.82,1.1 182 1801 0.2951 0.923 0.795,1.07 176 1750
316 Substance addiction and disorders mental disorders Both 0.6166 0.99 0.952,1.03 2799 26014 0.9204 1.01 0.911,1.11 420 5039
316.1 Polyneuropathy due to drugs mental disorders Both 0.3837 1.04 0.952,1.14 518 5180 0.9204 1.01 0.911,1.11 420 5039
317 Alcohol-related disorders mental disorders Both 0.7727 0.993 0.948,1.04 1948 17547 0.6095 0.97 0.863,1.09 315 3246
317.1 Alcoholism mental disorders Both 0.6808 1.01 0.959,1.07 1517 14733 0.6095 0.97 0.863,1.09 315 3246
317.11 Alcoholic liver damage mental disorders Both 0.5689 0.967 0.863,1.08 335 3336 0.6095 0.97 0.863,1.09 315 3246
318 Tobacco use disorder mental disorders Both 0.3258 1.01 0.988,1.04 9473 26924 0.4875 1.01 0.984,1.03 9021 26293
320 Meningitis neurological Both 0.2113 0.93 0.831,1.04 319 3181 0.1879 0.926 0.827,1.04 314 3066
323 Encephalitis neurological Both 0.6792 0.965 0.817,1.14 148 1475 0.9908 1.0 0.834,1.2 122 1216
323.8 Encephalitis, non-infectious neurological Both 0.873 1.01 0.847,1.22 125 1245 0.9908 1.0 0.834,1.2 122 1216
324 Other CNS infection and poliomyelitis neurological Both 0.4966 1.05 0.918,1.19 245 2440 0.6918 1.03 0.898,1.18 233 2334
327 Sleep disorders neurological Both 0.7345 1.0 0.982,1.03 11517 26652 0.003388 0.653 0.491,0.868 54 534
327.1 Hypersomnia neurological Both 0.8241 0.994 0.941,1.05 1403 13919 0.811 0.993 0.94,1.05 1362 13480
327.3 Sleep apnea neurological Both 0.3228 1.01 0.988,1.04 8293 26193 0.3034 1.01 0.987,1.04 6299 24768
327.31 Central/nonobstroctive sleep apnea neurological Both 0.1406 1.09 0.972,1.22 326 3234 0.123 1.09 0.976,1.23 319 3108
327.32 Obstructive sleep apnea neurological Both 0.3459 1.01 0.986,1.04 6534 25537 0.3034 1.01 0.987,1.04 6299 24768
327.4 Insomnia neurological Both 0.4018 0.986 0.954,1.02 4197 25860 0.1138 0.945 0.881,1.01 854 8446
327.41 Organic or persistent insomnia neurological Both 0.1236 0.947 0.884,1.01 881 8743 0.1138 0.945 0.881,1.01 854 8446
327.5 Parasomnia neurological Both 0.4046 0.96 0.871,1.06 459 4583 0.263 0.945 0.857,1.04 442 4424
327.6 Circadian rhythm sleep disorder neurological Both 0.8166 1.02 0.872,1.19 174 1738 0.8035 1.02 0.872,1.19 171 1681
327.7 Sleep related movement disorders neurological Both 0.0631 0.949 0.897,1.0 1364 13620 0.003388 0.653 0.491,0.868 54 534
327.71 Restless legs syndrome neurological Both 0.0955 0.951 0.896,1.01 1214 12132 0.1754 0.959 0.903,1.02 1173 11722
327.72 Sleep related leg cramps neurological Both 0.006457 0.677 0.511,0.897 55 550 0.003388 0.653 0.491,0.868 54 534
331 Other cerebral degenerations neurological Both 0.6442 1.02 0.938,1.11 602 5935 0.4375 1.05 0.934,1.17 334 3277
331.1 Hydrocephalus neurological Both 0.9311 1.01 0.885,1.14 246 2447 0.7551 1.02 0.896,1.16 239 2370
331.9 Cerebral degeneration, unspecified neurological Both 0.6295 1.03 0.919,1.15 349 3423 0.4375 1.05 0.934,1.17 334 3277
332 Parkinson's disease neurological Both 0.1153 0.913 0.815,1.02 333 3321 0.1016 0.908 0.809,1.02 322 3195
333 Extrapyramidal disease and abnormal movement disorders neurological Both 0.3184 0.978 0.935,1.02 2169 20920 0.7534 0.959 0.739,1.25 61 612
333.1 Essential tremor neurological Both 0.6109 1.02 0.938,1.12 551 5488 0.7499 1.01 0.929,1.11 534 5280
333.2 Myoclonus neurological Both 0.1841 1.14 0.941,1.37 117 1160 0.1459 1.16 0.951,1.41 107 1120
333.4 Torsion dystonia neurological Both 0.5023 0.959 0.847,1.08 266 2646 0.3999 0.948 0.837,1.07 261 2556
333.8 Other degenerative diseases of the basal ganglia neurological Both 0.5483 0.925 0.717,1.19 64 640 0.7534 0.959 0.739,1.25 61 612
334 Degenerative disease of the spinal cord neurological Both 0.9397 1.0 0.934,1.08 874 8734 0.6792 1.06 0.806,1.39 56 545
334.1 Spinocerebellar disease neurological Both 0.5058 1.09 0.84,1.42 64 631 0.4036 1.12 0.855,1.48 62 609
334.2 Anterior horn cell disease neurological Both 0.9484 1.01 0.818,1.24 92 920 0.6792 1.06 0.806,1.39 56 545
334.21 Amyotrophic Lateral Sclerosis neurological Both 0.7943 1.04 0.792,1.36 57 570 0.6792 1.06 0.806,1.39 56 545
335 Multiple sclerosis neurological Both 0.597 0.97 0.868,1.09 330 3284 0.6353 0.973 0.868,1.09 320 3180
337 Disorders of the autonomic nervous system neurological Both 0.3334 0.957 0.875,1.05 528 5257 0.413 0.937 0.803,1.09 178 1775
337.1 Peripheral autonomic neuropathy neurological Both 0.271 0.919 0.79,1.07 185 1837 0.413 0.937 0.803,1.09 178 1775
338 Pain neurological Both 0.4102 0.992 0.972,1.01 16189 22165 0.2158 0.984 0.959,1.01 7937 21625
338.1 Acute pain neurological Both 0.5902 0.994 0.973,1.02 12567 22166 0.375 0.99 0.968,1.01 12007 21638
338.2 Chronic pain neurological Both 0.3055 0.987 0.962,1.01 8223 22154 0.2158 0.984 0.959,1.01 7937 21625
339 Other headache syndromes neurological Both 0.2559 1.01 0.99,1.04 8578 27793 0.2489 1.01 0.99,1.04 8334 26891
340 Migraine neurological Both 0.7161 1.01 0.976,1.04 5377 24263 0.6353 1.01 0.97,1.05 2793 18088
340.1 Migrain with aura neurological Both 0.7638 1.01 0.967,1.05 2862 18665 0.6353 1.01 0.97,1.05 2793 18088
341 Other demyelinating diseases of central nervous system neurological Both 0.3062 0.904 0.745,1.1 111 1105 0.2188 0.885 0.728,1.08 108 1069
342 Hemiplegia neurological Both 0.4335 1.04 0.937,1.16 360 3589 0.3565 1.05 0.943,1.18 348 3457
343 Infantile cerebral palsy neurological Both 0.6607 1.05 0.832,1.34 75 750 0.6339 1.06 0.834,1.35 73 740
344 Other paralytic syndromes neurological Both 0.4188 0.964 0.882,1.05 564 5640 0.3741 0.96 0.877,1.05 545 5457
345 Epilepsy, recurrent seizures, convulsions neurological Both 0.0195 0.948 0.906,0.991 2084 20790 0.0871 0.96 0.916,1.01 1917 19021
345.1 Epilepsy neurological Both 0.08511 0.929 0.855,1.01 607 6053 0.169 0.933 0.844,1.03 422 4200
345.11 Generalized convulsive epilepsy neurological Both 0.0389 0.858 0.741,0.992 196 1960 0.04677 0.861 0.743,0.998 190 1920
345.12 Partial epilepsy neurological Both 0.1795 0.935 0.847,1.03 434 4333 0.169 0.933 0.844,1.03 422 4200
345.3 Convulsions neurological Both 0.05012 0.955 0.911,1.0 1967 19598 0.0871 0.96 0.916,1.01 1917 19021
346 Abnormal findings on study of brain and/or nervous system neurological Both 0.873 0.986 0.828,1.17 142 1404 0.3281 0.894 0.713,1.12 85 859
346.1 Nonspecific abnormal findings on radiological and other examination of skull and head neurological Both 0.6457 1.01 0.956,1.08 1196 11927 0.6607 1.01 0.954,1.08 1149 11496
346.2 Nonspecific abnormal results of function study of brain and central nervous system neurological Both 0.861 0.981 0.79,1.22 87 860 0.9863 0.998 0.799,1.25 82 837
346.3 Nonspecific abnormal findings in cerebrospinal fluid neurological Both 0.4325 0.915 0.734,1.14 90 884 0.3281 0.894 0.713,1.12 85 859
347 Cataplexy and narcolepsy neurological Both 0.06918 0.794 0.618,1.02 67 670 0.07943 0.799 0.622,1.03 67 656
348 Other conditions of brain neurological Both 0.9616 0.999 0.946,1.05 1424 14226 0.2698 0.974 0.93,1.02 1931 19294
348.2 Cerebral edema and compression of brain neurological Both 0.5902 1.02 0.947,1.1 747 7463 0.6577 1.02 0.942,1.1 726 7237
348.4 Cerebral cysts neurological Both 0.5689 1.04 0.9,1.21 195 1945 0.9462 1.01 0.865,1.17 191 1888
348.7 Coma neurological Both 0.778 1.02 0.872,1.2 162 1620 0.7762 1.02 0.871,1.2 158 1576
348.8 Encephalopathy, not elsewhere classified neurological Both 0.1406 0.941 0.867,1.02 636 6331 0.14 0.939 0.863,1.02 597 6082
348.9 Other conditions of brain, NOS neurological Both 0.235 0.973 0.929,1.02 2001 19979 0.2698 0.974 0.93,1.02 1931 19294
349 Other and unspecified disorders of the nervous system neurological Both 0.04074 0.926 0.86,0.997 775 7750 0.04365 0.926 0.859,0.998 745 7464
350 Abnormal movement neurological Both 0.4656 1.01 0.982,1.04 5109 32314 0.2477 1.06 0.96,1.17 422 4311
350.1 Abnormal involuntary movements neurological Both 0.3243 1.02 0.98,1.06 2464 24243 0.2449 1.03 0.983,1.07 2369 23429
350.2 Abnormality of gait neurological Both 0.7379 0.993 0.956,1.03 2979 25007 0.8222 0.996 0.957,1.04 2856 24149
350.3 Lack of coordination neurological Both 0.7278 1.01 0.941,1.09 773 7693 0.7096 1.01 0.941,1.09 749 7449
350.5 Abnormal reflex neurological Both 0.3936 1.08 0.91,1.27 143 1430 0.3573 1.08 0.915,1.28 141 1364
350.6 Disturbances of sensation of smell and taste neurological Both 0.1742 1.07 0.97,1.18 448 4480 0.2477 1.06 0.96,1.17 422 4311
351 Other peripheral nerve disorders neurological Both 0.787 1.0 0.976,1.03 5685 28844 0.6934 1.01 0.977,1.04 5454 27963
352 Disorders of other cranial nerves neurological Both 0.2594 1.03 0.977,1.09 1412 14120 0.597 1.02 0.941,1.11 618 6150
352.1 Trigeminal nerve disorders [CN5] neurological Both 0.4864 1.04 0.939,1.14 440 4393 0.4027 1.04 0.945,1.15 429 4225
352.2 Facial nerve disorders [CN7] neurological Both 0.6339 1.02 0.94,1.11 640 6400 0.597 1.02 0.941,1.11 618 6150
353 Nerve root and plexus disorders neurological Both 0.4236 1.01 0.979,1.05 3295 28097 0.3664 0.906 0.731,1.12 91 902
353.1 Nerve plexus lesions neurological Both 0.5433 1.04 0.924,1.16 308 3077 0.5129 1.04 0.925,1.17 300 3009
353.2 Nerve root lesions neurological Both 0.5093 0.931 0.754,1.15 94 930 0.3664 0.906 0.731,1.12 91 902
355 Complex regional/central pain syndrome neurological Both 0.2323 0.94 0.85,1.04 419 4170 0.5248 1.03 0.946,1.11 629 6298
355.1 Chronic pain syndrome neurological Both 0.492 1.03 0.949,1.11 654 6509 0.5248 1.03 0.946,1.11 629 6298
356 Hereditary and idiopathic peripheral neuropathy neurological Both 0.1019 1.04 0.992,1.1 1728 17176 0.07943 1.05 0.995,1.1 1623 16563
357 Inflammatory and toxic neuropathy neurological Both 0.0257 1.05 1.01,1.09 2467 24091 0.02754 1.05 1.01,1.1 2296 23274
358 Myoneural disorders neurological Both 0.5957 0.981 0.914,1.05 845 8441 0.08318 0.812 0.641,1.03 82 827
358.1 Myasthenia gravis neurological Both 0.04365 0.791 0.63,0.994 85 850 0.08318 0.812 0.641,1.03 82 827
359 Muscular dystrophies and other myopathies neurological Both 0.6982 1.01 0.945,1.09 868 8655 0.7295 1.01 0.942,1.09 797 8031
359.1 Muscular dystrophies neurological Both 0.3573 1.13 0.868,1.48 52 520 0.3214 1.15 0.875,1.5 51 507
359.2 Myopathy neurological Both 0.6546 1.02 0.946,1.09 833 8306 0.7295 1.01 0.942,1.09 797 8031
360 Disorders of the globe sense organs Both 0.3573 0.909 0.741,1.11 102 1013 0.2767 0.89 0.722,1.1 96 974
361 Retinal detachments and defects sense organs Both 0.1514 0.938 0.859,1.02 528 5265 0.5164 0.954 0.828,1.1 208 2131
361.1 Retinal detachment with retinal defect sense organs Both 0.3311 0.934 0.814,1.07 225 2226 0.5164 0.954 0.828,1.1 208 2131
362 Other retinal disorders sense organs Both 0.1476 0.969 0.929,1.01 2489 18838 0.695 0.971 0.836,1.13 186 1926
362.2 Degeneration of macula and posterior pole of retina sense organs Both 0.0537 0.949 0.9,1.0 1529 12328 0.1718 0.96 0.905,1.02 1256 10467
362.21 Macular degeneration, dry sense organs Both 0.3715 0.948 0.843,1.07 313 2650 0.3184 0.94 0.832,1.06 291 2522
362.22 Macular degeneration, wet sense organs Both 0.2188 0.882 0.723,1.08 108 881 0.4227 0.918 0.744,1.13 98 842
362.23 Cystoid macular degeneration of retina sense organs Both 0.007079 0.848 0.752,0.956 285 2777 0.006918 0.843 0.745,0.954 267 2657
362.26 Macular puckering of retina sense organs Both 0.5333 0.975 0.898,1.06 645 6254 0.6295 0.98 0.902,1.06 614 5998
362.27 Drusen (degenerative) of retina sense organs Both 0.241 0.936 0.837,1.05 335 3205 0.4207 0.954 0.851,1.07 315 3063
362.29 Macular degeneration (senile) of retina NOS sense organs Both 0.09772 0.953 0.9,1.01 1323 10928 0.1718 0.96 0.905,1.02 1256 10467
362.3 Other nondiabetic retinopathy sense organs Both 0.04786 0.922 0.851,0.999 653 6476 0.3467 0.944 0.836,1.06 278 2810
362.31 Separation of retinal layers sense organs Both 0.2553 0.934 0.83,1.05 296 2938 0.3467 0.944 0.836,1.06 278 2810
362.4 Retinal vascular changes and abnomalities sense organs Both 0.5728 0.972 0.882,1.07 449 4295 0.826 0.989 0.895,1.09 427 4122
362.6 Peripheral retinal degenerations sense organs Both 0.877 1.01 0.89,1.15 262 2600 0.8185 1.02 0.893,1.15 252 2489
362.7 Hereditary retinal dystrophies sense organs Both 0.9661 1.0 0.832,1.21 124 1233 0.8054 0.976 0.802,1.19 114 1185
362.8 Retinal hemorrhage/ischemia sense organs Both 0.8954 0.989 0.842,1.16 160 1570 0.9162 1.01 0.855,1.19 153 1518
362.9 Retinal edema sense organs Both 0.3184 0.93 0.806,1.07 202 2001 0.695 0.971 0.836,1.13 186 1926
363 Chorioretinal inflammations, scars, and other disorders of choroid sense organs Both 0.2143 1.07 0.962,1.19 375 3665 0.9594 1.0 0.878,1.15 232 2344
363.3 Chorioretinal scars sense organs Both 0.8299 0.986 0.867,1.12 249 2430 0.9594 1.0 0.878,1.15 232 2344
364 Corneal opacity and other disorders of cornea sense organs Both 0.8414 1.01 0.937,1.08 809 7919 0.4539 0.906 0.701,1.17 65 655
364.1 Corneal opacity sense organs Both 0.1178 0.91 0.808,1.02 294 2930 0.1545 0.915 0.811,1.03 281 2826
364.2 Corneal edema sense organs Both 0.5546 0.934 0.746,1.17 84 819 0.7379 0.961 0.761,1.21 79 788
364.4 Corneal degenerations sense organs Both 0.5943 0.967 0.855,1.09 274 2719 0.7047 0.976 0.861,1.11 265 2633
364.5 Corneal dystrophy sense organs Both 0.3733 1.05 0.945,1.16 377 3673 0.7345 1.03 0.888,1.18 202 1935
364.51 Fuchs' dystrophy sense organs Both 0.8511 1.01 0.88,1.17 207 2008 0.7345 1.03 0.888,1.18 202 1935
364.9 Cornea replaced by transplant sense organs Both 0.2153 0.853 0.664,1.1 69 677 0.4539 0.906 0.701,1.17 65 655
365 Glaucoma sense organs Both 0.7244 0.992 0.946,1.04 1986 17152 0.0537 0.852 0.725,1.0 165 1639
365.1 Open-angle glaucoma sense organs Both 0.8511 0.991 0.905,1.09 523 4963 0.4667 1.05 0.923,1.19 267 2484
365.11 Primary open angle glaucoma sense organs Both 0.5861 1.04 0.914,1.17 281 2609 0.4667 1.05 0.923,1.19 267 2484
365.2 Primary angle-closure glaucoma sense organs Both 0.04365 0.852 0.729,0.995 179 1707 0.0537 0.852 0.725,1.0 165 1639
366 Cataract sense organs Both 0.2786 0.984 0.956,1.01 6335 23476 0.4613 0.986 0.951,1.02 3640 19699
366.1 Nonsenile Cataract sense organs Both 0.4036 0.934 0.794,1.1 163 1622 0.4093 0.933 0.792,1.1 158 1562
366.2 Senile cataract sense organs Both 0.3148 0.982 0.948,1.02 3827 20410 0.4613 0.986 0.951,1.02 3640 19699
367 Disorders of refraction and accommodation; blindness and low vision sense organs Both 0.4732 1.01 0.983,1.04 6553 31745 0.1194 1.05 0.986,1.13 940 9325
367.1 Myopia sense organs Both 0.7691 0.995 0.961,1.03 3578 28818 0.6442 0.992 0.957,1.03 3450 27975
367.2 Astigmatism sense organs Both 0.7362 0.993 0.956,1.03 2892 26106 0.7278 0.993 0.955,1.03 2781 25289
367.4 Presbyopia sense organs Both 0.984 1.0 0.964,1.04 3297 24582 0.9078 0.998 0.961,1.04 3144 23713
367.8 Hypermetropia sense organs Both 0.4831 1.02 0.967,1.07 1504 14729 0.4345 1.02 0.968,1.08 1437 14181
367.9 Blindness and low vision sense organs Both 0.1086 1.06 0.988,1.13 976 9663 0.1194 1.05 0.986,1.13 940 9325
368 Visual disturbances sense organs Both 0.1706 1.02 0.99,1.06 4287 32818 0.2523 1.14 0.908,1.44 84 853
368.1 Amblyopia sense organs Both 0.9977 1.0 0.911,1.1 484 4830 0.9162 1.01 0.915,1.1 469 4653
368.2 Diplopia and disorders of binocular vision sense organs Both 0.3548 1.03 0.963,1.11 822 8186 0.3954 1.03 0.96,1.11 799 7905
368.3 Anisometropia sense organs Both 0.6823 1.03 0.881,1.21 166 1648 0.4656 1.06 0.903,1.25 163 1589
368.4 Visual field defects sense organs Both 0.3228 0.966 0.902,1.03 879 8777 0.3882 0.97 0.904,1.04 844 8436
368.9 Subjective visual disturbances sense organs Both 0.2089 1.05 0.974,1.13 829 8268 0.2523 1.14 0.908,1.44 84 853
368.91 Psychophysical visual disturbances sense organs Both 0.2113 1.16 0.921,1.45 89 885 0.2523 1.14 0.908,1.44 84 853
369 Infection of the eye sense organs Both 0.2388 1.03 0.983,1.07 2328 22262 0.166 1.03 0.986,1.08 1912 18840
369.2 Eye infection, viral sense organs Both 0.2723 1.06 0.954,1.18 372 3688 0.1722 1.08 0.967,1.21 350 3571
369.5 Conjunctivitis, infectious sense organs Both 0.2911 1.03 0.979,1.07 1974 19408 0.166 1.03 0.986,1.08 1912 18840
370 Keratitis sense organs Both 0.3936 0.973 0.913,1.04 1051 10280 0.4581 0.937 0.79,1.11 145 1382
370.1 Corneal ulcer sense organs Both 0.2089 0.902 0.767,1.06 164 1630 0.3776 0.929 0.788,1.09 160 1586
370.2 Superficial keratitis sense organs Both 0.6998 0.98 0.883,1.09 394 3916 0.5689 0.969 0.871,1.08 378 3795
370.3 Keratoconjunctivitis sense organs Both 0.7907 0.988 0.904,1.08 531 5159 0.4581 0.937 0.79,1.11 145 1382
370.31 Keratoconjunctivitis sicca sense organs Both 0.3972 0.93 0.787,1.1 150 1432 0.4581 0.937 0.79,1.11 145 1382
371 Inflammation of the eye sense organs Both 0.9594 0.999 0.963,1.04 3269 26161 0.1303 0.849 0.687,1.05 99 939
371.1 Uveitis, noninfectious or NOS sense organs Both 0.9226 0.995 0.896,1.1 394 3892 0.869 1.01 0.907,1.12 377 3769
371.2 Conjunctivitis, noninfectious sense organs Both 0.9908 1.0 0.922,1.08 651 6462 0.4064 1.04 0.949,1.14 515 5088
371.21 Allergic conjunctivitis sense organs Both 0.5272 1.03 0.942,1.12 532 5279 0.4064 1.04 0.949,1.14 515 5088
371.3 Inflammation of eyelids sense organs Both 0.5297 1.01 0.972,1.06 2523 21781 0.1303 0.849 0.687,1.05 99 939
371.33 Noninfectious dermatoses of eyelid sense organs Both 0.1216 0.845 0.683,1.05 100 979 0.1303 0.849 0.687,1.05 99 939
372 Disorders of conjunctiva sense organs Both 0.8433 0.993 0.923,1.07 827 8153 0.9183 1.0 0.932,1.08 793 7873
374 Other disorders of eyelids sense organs Both 0.7145 1.01 0.964,1.06 2093 18512 0.5754 1.02 0.947,1.1 722 7122
374.1 Ectropion or entropion sense organs Both 0.1567 1.08 0.969,1.21 337 3251 0.1279 1.09 0.975,1.23 321 3123
374.2 Lagophthalmos sense organs Both 0.5902 1.04 0.897,1.21 192 1900 0.4198 1.06 0.914,1.24 185 1837
374.3 Ptosis of eyelid sense organs Both 0.561 0.979 0.911,1.05 817 8140 0.6871 0.985 0.916,1.06 782 7843
374.6 Dermatochalasis sense organs Both 0.492 1.03 0.953,1.11 759 7426 0.5754 1.02 0.947,1.1 722 7122
375 Disorders of lacrimal system sense organs Both 0.6457 0.991 0.951,1.03 2683 21054 0.7834 1.02 0.909,1.13 344 3429
375.1 Dry eyes sense organs Both 0.5649 0.989 0.951,1.03 2966 21823 0.7816 0.994 0.956,1.03 2837 21086
375.2 Epiphora sense organs Both 0.9397 1.0 0.9,1.12 356 3540 0.7834 1.02 0.909,1.13 344 3429
376 Disorders of the orbit sense organs Both 0.7516 1.02 0.903,1.15 285 2814 0.826 1.01 0.896,1.15 281 2725
377 Disorders of optic nerve and visual pathways sense organs Both 0.6918 0.985 0.912,1.06 706 7010 0.9863 0.999 0.909,1.1 457 4477
377.1 Optic atrophy sense organs Both 0.4864 1.05 0.91,1.22 200 1997 0.5188 1.05 0.905,1.22 194 1920
377.3 Optic neuritis/neuropathy sense organs Both 0.7063 0.982 0.894,1.08 468 4627 0.9863 0.999 0.909,1.1 457 4477
378 Strabismus and other disorders of binocular eye movements sense organs Both 0.2985 1.04 0.969,1.11 969 9602 0.5916 1.03 0.913,1.17 273 2636
378.1 Strabismus (not specified as paralytic) sense organs Both 0.6353 1.02 0.939,1.11 617 6131 0.6081 1.02 0.94,1.11 601 5924
378.2 Nystagmus and other irregular eye movements sense organs Both 0.5458 1.06 0.881,1.27 138 1371 0.4699 1.07 0.89,1.29 136 1332
378.5 Paralytic strabismus sense organs Both 0.5508 1.04 0.917,1.18 275 2720 0.5916 1.03 0.913,1.17 273 2636
379 Other disorders of eye sense organs Both 0.8017 1.0 0.97,1.04 3593 24835 0.1343 1.06 0.983,1.13 843 8329
379.1 Scleritis and episcleritis sense organs Both 0.01202 1.24 1.05,1.46 140 1379 0.003981 1.28 1.08,1.51 134 1339
379.2 Disorders of vitreous body sense organs Both 0.9397 1.0 0.961,1.04 2559 18709 0.6081 1.01 0.969,1.06 2435 17984
379.3 Aphakia and other disorders of lens sense organs Both 0.2432 0.878 0.705,1.09 87 838 0.1879 0.859 0.684,1.08 82 805
379.4 Anomalies of pupillary function sense organs Both 0.7362 0.977 0.852,1.12 231 2303 0.9333 0.994 0.864,1.14 224 2222
379.5 Disorders of iris and ciliary body sense organs Both 0.5929 1.04 0.904,1.19 215 2128 0.6966 0.947 0.722,1.24 57 591
379.51 Pigmentary iris degeneration sense organs Both 0.8166 0.969 0.746,1.26 61 610 0.6966 0.947 0.722,1.24 57 591
379.9 Pain, swelling or discharge of eye sense organs Both 0.1303 1.06 0.984,1.13 870 8594 0.1343 1.06 0.983,1.13 843 8329
380 Disorders of external ear sense organs Both 0.9162 0.997 0.948,1.05 1634 15553 0.1199 1.04 0.99,1.09 1886 17981
380.1 Otitis externa sense organs Both 0.2158 0.962 0.905,1.02 1124 11213 0.3133 0.969 0.91,1.03 1092 10881
380.4 Impacted cerumen sense organs Both 0.2612 1.03 0.981,1.07 1985 18630 0.1199 1.04 0.99,1.09 1886 17981
381 Otitis media and Eustachian tube disorders sense organs Both 0.1156 0.971 0.937,1.01 3291 29339 0.1832 0.921 0.816,1.04 289 2865
381.1 Otitis media sense organs Both 0.278 0.977 0.937,1.02 2402 23549 0.2649 0.974 0.93,1.02 1982 19617
381.11 Suppurative and unspecified otitis media sense organs Both 0.1656 0.968 0.925,1.01 2037 20175 0.2649 0.974 0.93,1.02 1982 19617
381.2 Eustachian tube disorders sense organs Both 0.1337 0.959 0.908,1.01 1393 13815 0.1596 0.961 0.909,1.02 1351 13382
381.3 Mastoiditis & related conditions sense organs Both 0.9683 1.0 0.838,1.2 126 1260 0.7834 1.03 0.854,1.23 124 1224
381.9 Otorrhea sense organs Both 0.1714 0.92 0.817,1.04 297 2960 0.1832 0.921 0.816,1.04 289 2865
382 Otalgia sense organs Both 0.271 0.97 0.919,1.02 1425 14188 0.2382 0.967 0.916,1.02 1381 13772
383 Otosclerosis sense organs Both 0.2951 0.905 0.75,1.09 112 1120 0.302 0.905 0.749,1.09 110 1076
384 Other disorders of tympanic membrane sense organs Both 0.9954 1.0 0.903,1.11 397 3962 0.5916 0.969 0.862,1.09 312 3085
384.4 Perforation of tympanic membrane sense organs Both 0.5821 0.968 0.863,1.09 318 3180 0.5916 0.969 0.862,1.09 312 3085
385 Other disorders of middle ear and mastoid sense organs Both 0.3436 0.949 0.852,1.06 358 3580 0.9705 0.996 0.816,1.22 101 997
385.3 Cholesteatoma sense organs Both 0.3243 0.935 0.818,1.07 245 2450 0.3199 0.934 0.815,1.07 239 2398
385.5 Tympanosclerosis and middle ear disease related to otitis media sense organs Both 0.9247 1.01 0.829,1.23 103 1025 0.9705 0.996 0.816,1.22 101 997
386 Vertiginous syndromes and other disorders of vestibular system sense organs Both 0.399 0.977 0.926,1.03 1441 14255 0.1096 0.976 0.947,1.01 5112 30636
386.1 Meniere's disease sense organs Both 0.7943 0.983 0.862,1.12 248 2464 0.7328 0.977 0.855,1.12 239 2372
386.2 Peripheral or central vertigo sense organs Both 0.2128 0.963 0.909,1.02 1209 11971 0.8851 0.995 0.928,1.07 851 8453
386.21 Central origin vertigo sense organs Both 0.8831 0.995 0.929,1.07 883 8759 0.8851 0.995 0.928,1.07 851 8453
386.3 Labyrinthitis sense organs Both 0.7211 1.01 0.951,1.08 1099 10904 0.7261 1.01 0.95,1.08 1058 10534
386.9 Dizziness and giddiness (Light-headedness and vertigo) sense organs Both 0.05623 0.972 0.944,1.0 5315 31605 0.1096 0.976 0.947,1.01 5112 30636
388 Other disorders of ear sense organs Both 0.1637 0.946 0.875,1.02 699 6960 0.1758 0.947 0.874,1.02 677 6729
389 Hearing loss sense organs Both 0.7691 1.0 0.977,1.03 6285 31750 0.7079 0.963 0.79,1.17 100 972
389.1 Sensorineural hearing loss sense organs Both 0.4753 1.01 0.977,1.05 3130 24231 0.5058 1.01 0.975,1.05 3004 23337
389.2 Conductive hearing loss sense organs Both 0.5224 0.975 0.903,1.05 717 7169 0.4864 0.973 0.9,1.05 699 6953
389.3 Degenerative and vascular disorders of ear sense organs Both 0.2275 1.12 0.934,1.33 143 1338 0.2404 1.11 0.93,1.33 140 1280
389.4 Tinnitus sense organs Both 0.561 0.985 0.937,1.04 1677 16701 0.542 0.984 0.935,1.04 1623 16080
389.5 Disorders of acoustic nerve sense organs Both 0.6776 0.959 0.787,1.17 101 1010 0.7079 0.963 0.79,1.17 100 972
394 Rheumatic disease of the heart valves circulatory system Both 0.5433 1.02 0.96,1.08 1177 11253 0.02512 1.12 1.01,1.23 452 4435
394.1 Mitral valve stenosis and aortic valve stenosis circulatory system Both 0.9484 1.0 0.891,1.13 284 2766 0.7709 1.02 0.903,1.15 281 2655
394.2 Mitral valve disease circulatory system Both 0.5598 1.03 0.928,1.15 378 3735 0.4645 1.04 0.935,1.16 366 3582
394.3 Aortic valve disease circulatory system Both 0.6457 0.963 0.819,1.13 150 1465 0.7834 0.977 0.83,1.15 147 1396
394.7 Disease of tricuspid valve circulatory system Both 0.03981 1.11 1.0,1.22 468 4624 0.02512 1.12 1.01,1.23 452 4435
395 Heart valve disorders circulatory system Both 0.8072 0.995 0.959,1.03 3169 23926 0.6546 1.02 0.948,1.09 863 7890
395.1 Nonrheumatic mitral valve disorders circulatory system Both 0.6442 1.01 0.963,1.06 1754 16787 0.5383 1.02 0.966,1.07 1692 16168
395.2 Nonrheumatic aortic valve disorders circulatory system Both 0.6668 0.989 0.939,1.04 1619 13932 0.8017 0.993 0.943,1.05 1563 13388
395.3 Nonrheumatic tricuspid valve disorders circulatory system Both 0.8472 1.01 0.908,1.13 373 3704 0.6934 1.02 0.916,1.14 357 3548
395.4 Nonrheumatic pulmonary valve disorders circulatory system Both 0.9661 0.995 0.799,1.24 84 831 0.8395 1.02 0.818,1.28 81 809
395.6 Heart valve replaced circulatory system Both 0.8974 1.0 0.937,1.08 878 8213 0.6546 1.02 0.948,1.09 863 7890
396 Abnormal heart sounds circulatory system Both 0.3565 0.984 0.951,1.02 3754 28453 0.4365 0.986 0.952,1.02 3603 27511
401 Hypertension circulatory system Both 0.673 0.995 0.973,1.02 18784 19071 0.1722 0.967 0.921,1.01 1941 12575
401.1 Essential hypertension circulatory system Both 0.6383 0.995 0.972,1.02 18655 19070 0.8511 0.998 0.975,1.02 17908 18642
401.2 Hypertensive heart and/or renal disease circulatory system Both 0.1349 0.967 0.924,1.01 2599 12045 0.2023 0.968 0.92,1.02 1896 10564
401.21 Hypertensive heart disease circulatory system Both 0.863 0.992 0.91,1.08 556 4628 0.867 0.992 0.908,1.09 525 4473
401.22 Hypertensive chronic kidney disease circulatory system Both 0.118 0.962 0.916,1.01 2015 10909 0.2023 0.968 0.92,1.02 1896 10564
401.3 Other hypertensive complications circulatory system Both 0.08511 0.959 0.915,1.01 2027 12961 0.1722 0.967 0.921,1.01 1941 12575
402 Elevated blood pressure reading without diagnosis of hypertension circulatory system Both 0.8185 1.01 0.961,1.05 2132 15248 0.7656 1.01 0.961,1.05 2050 14837
411 Ischemic Heart Disease circulatory system Both 0.2188 0.983 0.956,1.01 6970 25468 0.9705 0.998 0.888,1.12 314 3118
411.1 Unstable angina (intermediate coronary syndrome) circulatory system Both 0.3062 0.96 0.888,1.04 702 6842 0.2624 0.956 0.882,1.03 677 6569
411.2 Myocardial infarction circulatory system Both 0.0389 0.958 0.92,0.998 2849 17983 0.04571 0.959 0.92,0.999 2735 17300
411.3 Angina pectoris circulatory system Both 0.9099 0.997 0.951,1.05 1904 15218 0.7516 0.992 0.945,1.04 1823 14644
411.4 Coronary atherosclerosis circulatory system Both 0.1718 0.979 0.95,1.01 5938 22890 0.9057 0.988 0.814,1.2 111 1087
411.41 Aneurysm and dissection of heart circulatory system Both 0.7907 0.975 0.807,1.18 117 1149 0.9057 0.988 0.814,1.2 111 1087
411.8 Other chronic ischemic heart disease, unspecified circulatory system Both 0.1361 0.975 0.944,1.01 4877 21174 0.1683 0.977 0.945,1.01 4675 20412
411.9 Other acute and subacute forms of ischemic heart disease circulatory system Both 0.8299 0.988 0.882,1.11 335 3247 0.9705 0.998 0.888,1.12 314 3118
414 Other forms of chronic heart disease circulatory system Both 0.9484 0.999 0.956,1.04 2360 18485 0.2421 1.06 0.962,1.17 470 4652
414.2 ASCVD circulatory system Both 0.139 1.07 0.977,1.18 492 4846 0.2421 1.06 0.962,1.17 470 4652
415 Pulmonary heart disease circulatory system Both 0.5768 1.01 0.972,1.05 2726 25061 0.5585 1.03 0.942,1.12 565 5715
415.1 Acute pulmonary heart disease circulatory system Both 0.3214 1.03 0.974,1.08 1510 15045 0.5445 1.02 0.963,1.07 1391 14531
415.11 Pulmonary embolism and infarction, acute circulatory system Both 0.3013 1.03 0.975,1.08 1507 15014 0.5445 1.02 0.963,1.07 1391 14531
415.2 Chronic pulmonary heart disease circulatory system Both 0.9863 1.0 0.949,1.05 1506 14839 0.5585 1.03 0.942,1.12 565 5715
415.21 Primary pulmonary hypertension circulatory system Both 0.492 1.03 0.947,1.12 592 5901 0.5585 1.03 0.942,1.12 565 5715
416 Cardiomegaly circulatory system Both 0.6637 1.02 0.949,1.09 935 9293 0.6295 1.02 0.949,1.09 893 8957
418 Nonspecific chest pain circulatory system Both 0.859 1.0 0.979,1.03 10015 28233 0.9078 0.996 0.937,1.06 1144 11416
418.1 Precordial pain circulatory system Both 0.7907 0.992 0.934,1.05 1193 11816 0.9078 0.996 0.937,1.06 1144 11416
420 Carditis circulatory system Both 0.9226 0.997 0.941,1.06 1275 12633 0.865 0.993 0.911,1.08 573 5795
420.1 Myocarditis circulatory system Both 0.3041 1.12 0.899,1.41 76 752 0.1718 1.17 0.933,1.47 73 729
420.2 Pericarditis circulatory system Both 0.7762 1.01 0.935,1.09 684 6830 0.2877 1.12 0.907,1.39 90 877
420.21 Acute pericarditis circulatory system Both 0.04898 1.19 1.0,1.4 144 1435 0.01549 1.24 1.04,1.47 139 1391
420.22 Chronic pericarditis circulatory system Both 0.3648 1.1 0.892,1.36 92 912 0.2877 1.12 0.907,1.39 90 877
420.3 Endocarditis circulatory system Both 0.6039 0.978 0.899,1.06 602 5990 0.865 0.993 0.911,1.08 573 5795
425 Cardiomyopathy circulatory system Both 0.9419 0.998 0.948,1.05 1617 15758 0.7194 1.05 0.812,1.35 64 680
425.1 Primary/intrinsic cardiomyopathies circulatory system Both 0.9638 0.999 0.948,1.05 1557 15170 0.857 0.984 0.829,1.17 149 1500
425.11 Hypertrophic obstructive cardiomyopathy circulatory system Both 0.6237 0.96 0.816,1.13 171 1699 0.5794 0.954 0.808,1.13 164 1645
425.12 Other hypertrophic cardiomyopathy circulatory system Both 0.9705 1.0 0.848,1.19 154 1540 0.857 0.984 0.829,1.17 149 1500
425.2 Secondary/extrinsic cardiomyopathies circulatory system Both 0.1148 0.9 0.789,1.03 248 2480 0.1178 0.899 0.786,1.03 237 2404
425.8 Other cardiomyopathy circulatory system Both 0.9204 1.01 0.794,1.29 71 709 0.7194 1.05 0.812,1.35 64 680
426 Cardiac conduction disorders circulatory system Both 0.3404 0.988 0.963,1.01 9881 21221 0.4842 0.971 0.893,1.06 603 5495
426.2 Atrioventricular [AV] block circulatory system Both 0.2812 1.03 0.975,1.09 1527 9610 0.5023 0.944 0.799,1.12 152 1429
426.21 First degree AV block circulatory system Both 0.4539 1.03 0.961,1.09 1064 7510 0.3357 1.03 0.967,1.1 1024 7261
426.22 Mobitz II AV block circulatory system Both 0.9376 1.01 0.779,1.31 56 513 0.7727 1.04 0.797,1.36 52 495
426.23 Second degree AV block circulatory system Both 0.9354 0.993 0.847,1.17 161 1459 0.9795 1.0 0.852,1.18 154 1398
426.24 Atrioventricular block, complete circulatory system Both 0.8974 1.01 0.904,1.12 357 3041 0.7816 1.02 0.911,1.13 346 2929
426.25 Other heart block circulatory system Both 0.3606 0.927 0.789,1.09 161 1489 0.5023 0.944 0.799,1.12 152 1429
426.3 Bundle branch block circulatory system Both 0.2198 1.03 0.981,1.09 1775 11373 0.6653 1.02 0.94,1.1 686 5992
426.31 Right bundle branch block circulatory system Both 0.2541 1.04 0.974,1.1 1101 8763 0.1986 1.04 0.978,1.11 1059 8476
426.32 Left bundle branch block circulatory system Both 0.8035 1.01 0.935,1.09 721 6217 0.6653 1.02 0.94,1.1 686 5992
426.4 Anomalous atrioventricular excitation circulatory system Both 0.2825 0.875 0.686,1.12 62 611 0.2818 0.874 0.685,1.12 62 603
426.7 Abnormal electrocardiogram [ECG] [EKG] circulatory system Both 0.1778 0.982 0.956,1.01 8452 21094 0.2301 0.984 0.957,1.01 8066 20600
426.8 Other cardiac conduction disorders circulatory system Both 0.354 0.955 0.867,1.05 456 4529 0.5546 0.97 0.878,1.07 428 4385
426.9 Cardiac pacemaker/device in situ circulatory system Both 0.1227 0.954 0.899,1.01 1261 8802 0.4842 0.971 0.893,1.06 603 5495
426.91 Cardiac pacemaker in situ circulatory system Both 0.0912 0.939 0.873,1.01 836 6124 0.1901 0.952 0.883,1.02 803 5919
426.92 Cardiac defibrillator in situ circulatory system Both 0.3548 0.962 0.886,1.04 628 5698 0.4842 0.971 0.893,1.06 603 5495
427 Cardiac dysrhythmias circulatory system Both 0.1368 0.983 0.962,1.01 14018 21321 0.6683 0.992 0.956,1.03 3296 19668
427.1 Paroxysmal tachycardia, unspecified circulatory system Both 0.9977 1.0 0.953,1.05 1882 14769 0.8974 0.995 0.928,1.07 857 7711
427.11 Paroxysmal supraventricular tachycardia circulatory system Both 0.673 1.01 0.954,1.08 1193 11216 0.7328 1.01 0.951,1.07 1141 10899
427.12 Paroxysmal ventricular tachycardia circulatory system Both 0.6427 0.984 0.918,1.05 892 7975 0.8974 0.995 0.928,1.07 857 7711
427.2 Atrial fibrillation and flutter circulatory system Both 0.8913 1.0 0.967,1.04 4194 15493 0.7413 1.01 0.956,1.07 1549 9355
427.21 Atrial fibrillation circulatory system Both 0.7691 1.01 0.969,1.04 4097 15312 0.5984 1.01 0.973,1.05 3941 14864
427.22 Atrial flutter circulatory system Both 0.9099 1.0 0.951,1.06 1598 9674 0.7413 1.01 0.956,1.07 1549 9355
427.3 Other specified cardiac dysrhythmias circulatory system Both 0.5152 0.991 0.964,1.02 7129 21276 0.3954 0.988 0.96,1.02 6812 20781
427.4 Cardiac arrest and ventricular fibrillation circulatory system Both 0.984 1.0 0.906,1.11 419 4137 0.4446 1.05 0.931,1.18 304 3086
427.41 Ventricular fibrillation and flutter circulatory system Both 0.8551 0.986 0.844,1.15 167 1670 0.8492 0.985 0.839,1.16 158 1613
427.42 Cardiac arrest circulatory system Both 0.52 1.04 0.926,1.16 321 3186 0.4446 1.05 0.931,1.18 304 3086
427.5 Arrhythmia (cardiac) NOS circulatory system Both 0.2649 0.983 0.953,1.01 5521 21271 0.3802 0.986 0.956,1.02 5347 20776
427.6 Premature beats circulatory system Both 0.6223 0.988 0.94,1.04 1820 13218 0.631 0.978 0.891,1.07 496 4717
427.61 Supraventricular premature beats circulatory system Both 0.618 0.977 0.893,1.07 522 4879 0.631 0.978 0.891,1.07 496 4717
427.7 Tachycardia NOS circulatory system Both 0.6592 0.992 0.959,1.03 3980 21286 0.5636 0.99 0.956,1.02 3751 20791
427.8 Sinoatrial node dysfunction (Bradycardia) circulatory system Both 0.4645 0.972 0.9,1.05 738 6224 0.4529 0.97 0.897,1.05 701 6004
427.9 Palpitations circulatory system Both 0.5445 0.989 0.953,1.03 3420 20157 0.6683 0.992 0.956,1.03 3296 19668
428 Congestive heart failure; nonhypertensive circulatory system Both 0.3258 0.981 0.945,1.02 3326 19946 0.7396 0.99 0.931,1.05 1149 10245
428.1 Congestive heart failure (CHF) NOS circulatory system Both 0.1309 0.97 0.933,1.01 2965 19130 0.2432 0.976 0.938,1.02 2838 18489
428.2 Heart failure NOS circulatory system Both 0.3013 0.979 0.94,1.02 2781 17962 0.4786 0.985 0.945,1.03 2659 17360
428.3 Heart failure with reduced EF [Systolic or combined heart failure] circulatory system Both 0.6792 1.01 0.956,1.07 1288 11396 0.3266 1.03 0.971,1.09 1230 10994
428.4 Heart failure with preserved EF [Diastolic heart failure] circulatory system Both 0.5781 0.983 0.926,1.04 1208 10616 0.7396 0.99 0.931,1.05 1149 10245
429 Ill-defined descriptions and complications of heart disease circulatory system Both 0.4018 0.99 0.966,1.01 9394 27581 0.8954 1.01 0.921,1.1 553 5606
429.1 Heart transplant/surgery circulatory system Both 0.9727 1.0 0.932,1.08 823 8070 0.6067 1.02 0.948,1.1 799 7800
429.2 Abnormal function study of cardiovascular system circulatory system Both 0.514 0.989 0.958,1.02 4445 23965 0.6887 0.993 0.961,1.03 4251 23248
429.3 Symptoms involving cardiovascular system circulatory system Both 0.9397 1.0 0.975,1.03 7147 27443 0.778 1.0 0.977,1.03 6845 26702
429.9 Cardiac complications, not elsewhere classified circulatory system Both 0.7211 1.02 0.933,1.11 591 5816 0.8954 1.01 0.921,1.1 553 5606
430 Intracranial hemorrhage circulatory system Both 0.6531 0.981 0.904,1.07 633 6305 0.6823 1.03 0.892,1.19 194 1936
430.1 Subarachnoid hemorrhage circulatory system Both 0.8279 0.985 0.861,1.13 230 2300 0.9661 1.0 0.875,1.15 224 2229
430.2 Intracerebral hemorrhage circulatory system Both 0.2825 0.938 0.835,1.05 314 3132 0.3266 0.942 0.836,1.06 301 3023
430.3 Subdural hemorrhage circulatory system Both 0.8185 1.02 0.882,1.17 202 2017 0.6823 1.03 0.892,1.19 194 1936
433 Cerebrovascular disease circulatory system Both 0.8356 0.997 0.965,1.03 4361 26660 0.8433 0.991 0.905,1.08 513 5090
433.1 Occlusion and stenosis of precerebral arteries circulatory system Both 0.413 1.02 0.97,1.08 1533 12978 0.1982 1.19 0.912,1.56 56 575
433.11 Occlusion of cerebral arteries, with cerebral infarction circulatory system Both 0.4018 0.939 0.81,1.09 188 1858 0.4375 0.943 0.812,1.09 183 1780
433.12 Cerebral atherosclerosis circulatory system Both 0.2312 1.17 0.905,1.51 61 599 0.1982 1.19 0.912,1.56 56 575
433.2 Occlusion of cerebral arteries circulatory system Both 0.2704 1.03 0.98,1.08 1926 17593 0.2979 1.03 0.977,1.08 1790 16334
433.21 Cerebral artery occlusion, with cerebral infarction circulatory system Both 0.342 1.02 0.976,1.07 1862 17011 0.2979 1.03 0.977,1.08 1790 16334
433.3 Cerebral ischemia circulatory system Both 0.4159 0.981 0.938,1.03 2122 18040 0.8072 1.01 0.957,1.06 1739 15424
433.31 Transient cerebral ischemia circulatory system Both 0.975 1.0 0.953,1.05 1812 16062 0.8072 1.01 0.957,1.06 1739 15424
433.5 Cerebral aneurysm circulatory system Both 0.1694 0.931 0.841,1.03 408 4070 0.1578 0.929 0.838,1.03 400 3920
433.6 Acute, but ill-defined cerebrovascular disease circulatory system Both 0.4295 1.04 0.94,1.16 383 3803 0.4217 1.04 0.939,1.16 369 3655
433.8 Late effects of cerebrovascular disease circulatory system Both 0.826 0.99 0.906,1.08 534 5286 0.8433 0.991 0.905,1.08 513 5090
440 Atherosclerosis circulatory system Both 0.2244 0.971 0.926,1.02 1946 16499 0.6934 1.02 0.94,1.1 679 6526
440.1 Atherosclerosis of renal artery circulatory system Both 0.7568 0.977 0.843,1.13 187 1855 0.8318 0.984 0.848,1.14 183 1795
440.2 Atherosclerosis of the extremities circulatory system Both 0.06026 0.944 0.889,1.0 1166 11265 0.191 0.952 0.884,1.02 779 7658
440.21 Atherosclerosis of native arteries of the extremities with ulceration or gangrene circulatory system Both 0.2032 1.1 0.949,1.28 183 1815 0.1698 1.11 0.955,1.3 177 1743
440.22 Atherosclerosis of native arteries of the extremities with intermittent claudication circulatory system Both 0.1963 0.953 0.887,1.02 812 7979 0.191 0.952 0.884,1.02 779 7658
440.9 Atherosclerosis of aorta circulatory system Both 0.9441 0.997 0.924,1.08 702 6800 0.6934 1.02 0.94,1.1 679 6526
441 Vascular insufficiency of intestine circulatory system Both 0.5902 0.973 0.879,1.08 407 4039 0.2323 1.12 0.928,1.36 116 1151
441.1 Acute vascular insufficiency of intestine circulatory system Both 0.9506 1.0 0.871,1.16 206 2025 0.869 0.987 0.848,1.15 178 1953
441.2 Chronic vascular insufficiency of intestine circulatory system Both 0.2972 1.1 0.916,1.33 122 1207 0.2323 1.12 0.928,1.36 116 1151
442 Other aneurysm circulatory system Both 0.1282 0.967 0.925,1.01 2309 18098 0.118 0.91 0.809,1.02 315 3171
442.1 Aortic aneurysm circulatory system Both 0.5082 0.983 0.934,1.03 1703 13812 0.3483 1.03 0.965,1.11 948 8638
442.11 Abdominal aortic aneurysm circulatory system Both 0.7015 1.01 0.948,1.08 992 9021 0.3483 1.03 0.965,1.11 948 8638
442.2 Aneurysm of iliac artery circulatory system Both 0.2203 0.903 0.767,1.06 177 1769 0.2032 0.897 0.759,1.06 168 1693
442.3 Aneurysm of artery of lower extremity circulatory system Both 0.2328 0.9 0.757,1.07 137 1357 0.3013 0.912 0.765,1.09 134 1314
442.4 Arterial dissection circulatory system Both 0.06026 0.856 0.727,1.01 156 1555 0.03715 0.838 0.71,0.989 150 1496
442.8 Aneurysm of other specified artery circulatory system Both 0.0871 0.904 0.806,1.01 330 3300 0.118 0.91 0.809,1.02 315 3171
443 Peripheral vascular disease circulatory system Both 0.2512 0.975 0.934,1.02 2355 20353 0.6081 0.987 0.938,1.04 1675 14565
443.1 Raynaud's syndrome circulatory system Both 0.04571 0.919 0.846,0.998 608 6051 0.0955 0.931 0.856,1.01 589 5873
443.7 Peripheral angiopathy in diseases classified elsewhere circulatory system Both 0.9016 1.01 0.85,1.2 141 1375 0.778 0.975 0.815,1.17 133 1321
443.8 Other specified peripheral vascular diseases circulatory system Both 0.4325 0.981 0.936,1.03 1899 17476 0.5559 0.986 0.939,1.03 1820 16840
443.9 Peripheral vascular disease, unspecified circulatory system Both 0.5598 0.985 0.937,1.04 1747 15154 0.6081 0.987 0.938,1.04 1675 14565
444 Arterial embolism and thrombosis circulatory system Both 0.07586 1.07 0.993,1.16 675 6732 0.3148 1.1 0.914,1.32 123 1241
444.1 Arterial embolism and thrombosis of lower extremity artery circulatory system Both 0.2877 1.07 0.943,1.22 240 2392 0.26 1.08 0.945,1.23 232 2303
444.2 Embolism and thrombosis of abdominal aorta circulatory system Both 0.317 1.1 0.915,1.31 129 1282 0.3148 1.1 0.914,1.32 123 1241
446 Polyarteritis nodosa and allied conditions circulatory system Both 0.4121 1.05 0.94,1.16 367 3641 0.1941 1.09 0.955,1.25 223 2195
446.4 Wegener's granulomatosis circulatory system Both 0.01549 1.32 1.05,1.64 86 857 0.01072 1.34 1.07,1.68 84 828
446.5 Giant cell arteritis circulatory system Both 0.857 0.975 0.743,1.28 59 547 0.7079 0.949 0.72,1.25 57 523
446.9 Arteritis NOS circulatory system Both 0.3837 1.06 0.929,1.21 230 2285 0.1941 1.09 0.955,1.25 223 2195
447 Other disorders of arteries and arterioles circulatory system Both 0.8128 1.01 0.961,1.05 2116 18819 0.3936 1.04 0.954,1.13 611 6078
447.1 Stricture of artery circulatory system Both 0.6252 0.976 0.883,1.08 435 4322 0.7674 0.985 0.89,1.09 415 4169
447.7 Aortic ectasia circulatory system Both 0.3483 1.04 0.958,1.13 637 6315 0.3936 1.04 0.954,1.13 611 6078
448 Disease of capillaries circulatory system Both 0.9616 1.0 0.934,1.07 853 8472 0.8375 1.01 0.938,1.08 821 8176
450 Noninfectious disorders of lymphatic channels circulatory system Both 0.1923 1.03 0.984,1.09 1701 17006 0.2075 1.03 0.982,1.09 1638 16412
451 Phlebitis and thrombophlebitis circulatory system Both 0.1346 1.07 0.98,1.16 582 5764 0.5585 1.05 0.897,1.22 180 1845
451.2 Phlebitis and thrombophlebitis of lower extremities circulatory system Both 0.526 1.05 0.903,1.22 190 1888 0.5585 1.05 0.897,1.22 180 1845
452 Other venous embolism and thrombosis circulatory system Both 0.2636 1.02 0.985,1.06 3773 25068 0.1355 0.861 0.708,1.05 113 1158
452.1 Iatrogenic pulmonary embolism and infarction circulatory system Both 0.6561 0.969 0.841,1.12 228 2277 0.7534 0.977 0.847,1.13 220 2217
452.2 Deep vein thrombosis [DVT] circulatory system Both 0.4571 1.02 0.975,1.06 2623 22444 0.4932 1.01 0.973,1.06 2462 21827
452.8 Postphlebitic syndrome circulatory system Both 0.1858 0.879 0.726,1.06 119 1181 0.1355 0.861 0.708,1.05 113 1158
453 Chronic venous hypertension circulatory system Both 0.2624 0.914 0.781,1.07 173 1715 0.369 0.93 0.794,1.09 169 1657
454 Varicose veins circulatory system Both 0.471 0.984 0.942,1.03 2206 20243 0.8531 1.01 0.947,1.07 1149 11423
454.1 Varicose veins of lower extremity circulatory system Both 0.6714 0.99 0.944,1.04 1908 17574 0.8531 1.01 0.947,1.07 1149 11423
454.11 Varicose veins of lower extremity, symptomtic circulatory system Both 0.9204 1.0 0.945,1.06 1182 11754 0.8531 1.01 0.947,1.07 1149 11423
455 Hemorrhoids circulatory system Both 0.5309 1.01 0.978,1.04 4379 24588 0.743 1.01 0.973,1.04 4130 23957
456 Chronic venous insufficiency [CVI] circulatory system Both 0.1563 0.969 0.928,1.01 2303 20367 0.171 0.97 0.928,1.01 2224 19820
457 Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin circulatory system Both 0.5521 0.986 0.939,1.03 1946 14131 0.873 0.996 0.947,1.05 1735 13220
457.2 Encounter for long-term (current) use of antiplatelets/antithrombotics circulatory system Both 0.4416 0.953 0.844,1.08 287 2845 0.3491 0.942 0.83,1.07 268 2742
457.3 Encounter for long-term (current) use of aspirin circulatory system Both 0.631 0.988 0.941,1.04 1841 13661 0.873 0.996 0.947,1.05 1735 13220
458 Hypotension circulatory system Both 0.2588 0.981 0.949,1.01 4073 28546 0.2685 0.98 0.945,1.02 3401 26652
458.1 Orthostatic hypotension circulatory system Both 0.1618 0.955 0.896,1.02 1031 10176 0.157 0.953 0.892,1.02 959 9849
458.2 Iatrogenic hypotension circulatory system Both 0.4721 0.975 0.911,1.04 911 9084 0.4256 0.972 0.906,1.04 843 8764
458.9 Hypotension NOS circulatory system Both 0.2094 0.978 0.944,1.01 3641 27465 0.2685 0.98 0.945,1.02 3401 26652
459 Other disorders of circulatory system circulatory system Both 0.4732 0.987 0.953,1.02 3553 27674 0.6998 0.992 0.953,1.03 2650 22922
459.1 Hemorrhage NOS circulatory system Both 0.8453 0.992 0.913,1.08 619 6159 0.9977 1.0 0.918,1.09 572 5972
459.7 Blood vessel replaced circulatory system Both 0.3258 0.931 0.807,1.07 203 2030 0.3597 0.935 0.811,1.08 200 1955
459.9 Circulatory disease NEC circulatory system Both 0.5333 0.988 0.949,1.03 2757 23656 0.6998 0.992 0.953,1.03 2650 22922
464 Acute sinusitis respiratory Both 0.01202 0.956 0.924,0.99 3675 26562 0.01622 0.958 0.924,0.992 3546 25754
465 Acute upper respiratory infections of multiple or unspecified sites respiratory Both 0.3177 0.987 0.962,1.01 7223 30143 0.2938 0.941 0.841,1.05 334 3328
465.2 Acute pharyngitis respiratory Both 0.1161 0.973 0.941,1.01 3967 26715 0.2018 0.978 0.945,1.01 3859 25928
465.4 Acute laryngitis and tracheitis respiratory Both 0.2104 0.932 0.834,1.04 345 3441 0.2938 0.941 0.841,1.05 334 3328
470 Septal Deviations/Turbinate Hypertrophy respiratory Both 0.2234 1.03 0.98,1.09 1431 14130 0.2099 1.04 0.981,1.09 1399 13752
471 Nasal polyps respiratory Both 0.7244 0.983 0.894,1.08 475 4727 0.6368 0.977 0.887,1.08 460 4580
472 Chronic pharyngitis and nasopharyngitis respiratory Both 0.1245 0.957 0.905,1.01 1344 13251 0.1086 0.955 0.902,1.01 1298 12857
473 Diseases of the larynx and vocal cords respiratory Both 0.4436 0.984 0.943,1.03 2393 20985 0.1959 0.969 0.923,1.02 1826 17418
473.1 Chronic laryngitis respiratory Both 0.2432 0.851 0.648,1.12 57 562 0.1054 0.795 0.602,1.05 54 539
473.3 Paralysis/spasm of vocal cords or larynx respiratory Both 0.3954 0.961 0.878,1.05 517 5167 0.3556 0.957 0.873,1.05 503 5007
473.4 Voice disturbance respiratory Both 0.2871 0.975 0.93,1.02 1880 18033 0.1959 0.969 0.923,1.02 1826 17418
474 Acute and chronic tonsillitis respiratory Both 0.6427 0.981 0.906,1.06 685 6193 0.227 0.947 0.866,1.03 546 5065
474.1 Acute tonsillitis respiratory Both 0.7709 1.02 0.898,1.16 267 2507 0.7621 1.02 0.899,1.16 267 2480
474.2 Chronic tonsillitis and adenoiditis respiratory Both 0.1811 0.941 0.862,1.03 555 5166 0.227 0.947 0.866,1.03 546 5065
475 Chronic sinusitis respiratory Both 0.0955 0.97 0.935,1.01 3434 23149 0.1169 1.07 0.984,1.16 623 6236
475.9 Postnasal drip respiratory Both 0.08128 1.07 0.991,1.16 651 6441 0.1169 1.07 0.984,1.16 623 6236
476 Allergic rhinitis respiratory Both 0.1279 0.982 0.959,1.01 10205 23354 0.09333 0.98 0.957,1.0 9837 22660
477 Epistaxis or throat hemorrhage respiratory Both 0.8318 1.01 0.941,1.08 895 8841 0.7834 1.01 0.941,1.08 856 8543
478 Throat pain respiratory Both 0.2094 0.928 0.826,1.04 325 3233 0.2173 0.928 0.825,1.04 315 3138
479 Other upper respiratory disease respiratory Both 0.6081 0.992 0.96,1.02 4428 23338 0.6934 0.993 0.961,1.03 4283 22644
480 Pneumonia respiratory Both 0.07244 0.972 0.943,1.0 4823 30881 0.157 1.15 0.948,1.39 111 1129
480.1 Bacterial pneumonia respiratory Both 0.4093 1.03 0.96,1.11 860 8567 0.1774 0.852 0.675,1.08 77 786
480.11 Pneumococcal pneumonia respiratory Both 0.5702 1.03 0.928,1.15 372 3720 0.6353 1.03 0.922,1.14 354 3598
480.12 Pseudomonal pneumonia respiratory Both 0.5546 1.06 0.873,1.29 121 1192 0.6252 1.05 0.86,1.29 113 1152
480.13 MRSA pneumonia respiratory Both 0.1774 0.856 0.683,1.07 82 818 0.1774 0.852 0.675,1.08 77 786
480.2 Viral pneumonia respiratory Both 0.08913 1.16 0.978,1.38 147 1461 0.1503 1.14 0.954,1.36 137 1416
480.3 Pneumonia due to fungus (mycoses) respiratory Both 0.4064 0.922 0.761,1.12 117 1170 0.4169 0.923 0.762,1.12 116 1131
480.5 Bronchopneumonia and lung abscess respiratory Both 0.3334 1.1 0.909,1.33 119 1175 0.157 1.15 0.948,1.39 111 1129
481 Influenza respiratory Both 0.1959 0.958 0.897,1.02 990 9863 0.2265 0.96 0.898,1.03 945 9600
483 Acute bronchitis and bronchiolitis respiratory Both 0.6714 0.991 0.952,1.03 2615 24227 0.6902 0.992 0.952,1.03 2520 23500
495 Asthma respiratory Both 0.4198 0.989 0.963,1.02 6951 27725 0.7194 0.989 0.932,1.05 1217 12098
495.1 Chronic obstructive asthma respiratory Both 0.4887 1.04 0.93,1.16 341 3403 0.1626 0.829 0.638,1.08 57 567
495.11 Chronic obstructive asthma with exacerbation respiratory Both 0.1291 0.818 0.631,1.06 60 592 0.1626 0.829 0.638,1.08 57 567
495.2 Asthma with exacerbation respiratory Both 0.875 0.995 0.939,1.06 1251 12442 0.7194 0.989 0.932,1.05 1217 12098
496 Chronic airway obstruction respiratory Both 0.369 0.985 0.954,1.02 4444 23893 0.9572 1.0 0.906,1.11 406 4162
496.1 Emphysema respiratory Both 0.7328 1.01 0.961,1.06 1831 16712 0.7889 1.01 0.958,1.06 1718 16068
496.2 Chronic bronchitis respiratory Both 0.1626 0.974 0.939,1.01 3357 22668 0.2685 0.978 0.941,1.02 2906 20932
496.21 Obstructive chronic bronchitis respiratory Both 0.2844 0.979 0.943,1.02 3040 21701 0.2685 0.978 0.941,1.02 2906 20932
496.3 Bronchiectasis respiratory Both 0.6823 1.02 0.925,1.13 435 4329 0.9572 1.0 0.906,1.11 406 4162
497 Bronchitis respiratory Both 0.2661 0.97 0.919,1.02 1481 14700 0.3243 0.973 0.921,1.03 1419 14217
498 Acute bronchospasm respiratory Both 0.787 0.986 0.889,1.09 376 3745 0.8318 0.989 0.891,1.1 369 3622
499 Cystic fibrosis respiratory Both 0.8337 0.98 0.813,1.18 116 1160 0.7063 0.963 0.793,1.17 107 1130
500 Lung disease due to external agents respiratory Both 0.9268 1.0 0.91,1.11 428 4273 0.8222 1.03 0.791,1.34 62 620
500.1 Extrinsic allergic alveolitis respiratory Both 0.7031 1.04 0.835,1.31 81 810 0.8551 1.02 0.812,1.29 77 783
500.2 Pneumoconiosis respiratory Both 0.9954 0.999 0.771,1.3 65 640 0.8222 1.03 0.791,1.34 62 620
501 Pneumonitis due to inhalation of food or vomitus respiratory Both 0.3483 0.957 0.873,1.05 514 5078 0.3428 0.955 0.87,1.05 488 4905
502 Postinflammatory pulmonary fibrosis respiratory Both 0.8279 0.991 0.913,1.08 623 6192 0.9099 0.995 0.914,1.08 580 5979
503 Pulmonary congestion and hypostasis respiratory Both 0.6295 1.02 0.943,1.1 690 6875 0.6209 1.02 0.942,1.11 647 6636
504 Other alveolar and parietoalveolar pneumonopathy respiratory Both 0.7194 0.982 0.892,1.08 447 4454 0.526 1.04 0.913,1.2 226 2377
504.1 Idiopathic fibrosing alveolitis respiratory Both 0.4808 1.05 0.921,1.19 247 2456 0.526 1.04 0.913,1.2 226 2377
505 Other pulmonary inflamation or edema respiratory Both 0.6653 0.988 0.934,1.04 1352 13261 0.7464 0.991 0.935,1.05 1282 12793
506 Empyema and pneumothorax respiratory Both 0.6053 0.989 0.95,1.03 2588 22332 0.881 0.997 0.956,1.04 2488 21642
507 Pleurisy; pleural effusion respiratory Both 0.1274 1.03 0.991,1.08 2415 21828 0.1253 1.03 0.991,1.08 2262 21135
508 Pulmonary collapse; interstitial and compensatory emphysema respiratory Both 0.9183 1.0 0.957,1.05 2005 19256 0.8091 1.01 0.959,1.06 1855 18628
509 Respiratory failure, insufficiency, arrest respiratory Both 0.8531 1.0 0.966,1.04 3044 23898 0.867 1.01 0.936,1.08 802 8184
509.1 Respiratory failure respiratory Both 0.169 1.04 0.984,1.1 1466 14560 0.1127 1.05 0.99,1.1 1392 14071
509.2 Respiratory insufficiency respiratory Both 0.2917 1.04 0.969,1.11 928 9238 0.2104 1.05 0.975,1.12 884 8935
509.3 Pulmonary insufficiency or respiratory failure following trauma and surgery respiratory Both 0.2388 0.969 0.918,1.02 1500 14783 0.2685 0.97 0.919,1.02 1438 14286
509.8 Dependence on respirator [Ventilator] or supplemental oxygen respiratory Both 0.9057 1.0 0.936,1.08 848 8472 0.867 1.01 0.936,1.08 802 8184
510 Other diseases of lung respiratory Both 0.537 0.99 0.96,1.02 4671 30168 0.1549 1.14 0.952,1.36 121 1243
510.2 Lung transplant respiratory Both 0.1324 1.14 0.96,1.36 128 1274 0.1549 1.14 0.952,1.36 121 1243
512 Other symptoms of respiratory system respiratory Both 0.8279 0.998 0.977,1.02 14878 23476 0.8892 0.998 0.973,1.02 8274 22905
512.1 Wheezing respiratory Both 0.7096 0.988 0.927,1.05 1071 10626 0.8147 0.992 0.93,1.06 1031 10329
512.2 Painful respiration respiratory Both 0.9528 0.999 0.95,1.05 1765 17029 0.8395 1.01 0.956,1.06 1688 16579
512.3 Abnormal chest sounds respiratory Both 0.6776 1.03 0.899,1.18 229 2261 0.7261 1.03 0.892,1.18 213 2187
512.7 Shortness of breath respiratory Both 0.7586 0.996 0.97,1.02 7928 23452 0.7889 0.996 0.97,1.02 7559 22890
512.8 Cough respiratory Both 0.8492 1.0 0.976,1.03 7280 23469 0.7745 1.0 0.977,1.03 6980 22907
512.9 Other dyspnea respiratory Both 0.7586 0.996 0.971,1.02 8658 23467 0.8892 0.998 0.973,1.02 8274 22905
513 Respiratory abnormalities respiratory Both 0.236 1.01 0.991,1.04 10231 28110 0.4246 1.06 0.917,1.23 191 1985
513.3 Hypoventilation respiratory Both 0.3784 1.04 0.955,1.13 618 6146 0.6918 1.03 0.877,1.22 158 1600
513.31 Apnea respiratory Both 0.3006 1.06 0.947,1.19 314 3136 0.2877 1.07 0.948,1.2 308 3054
513.32 Orthopnea respiratory Both 0.5346 1.05 0.896,1.24 167 1662 0.6918 1.03 0.877,1.22 158 1600
513.4 Hyperventilation respiratory Both 0.2904 1.05 0.956,1.16 440 4383 0.2612 1.06 0.958,1.17 413 4238
513.8 Disorders of diaphragm respiratory Both 0.5662 1.04 0.904,1.2 206 2053 0.4246 1.06 0.917,1.23 191 1985
514 Abnormal findings examination of lungs respiratory Both 0.7889 0.996 0.965,1.03 4486 29229 0.5957 0.988 0.947,1.03 2308 21981
514.1 Abnormal results of function study of pulmonary system respiratory Both 0.8831 1.01 0.875,1.17 193 1914 0.7228 1.03 0.885,1.19 178 1835
514.2 Solitary pulmonary nodule respiratory Both 0.492 0.986 0.946,1.03 2489 22668 0.5957 0.988 0.947,1.03 2308 21981
516 Abnormal sputum respiratory Both 0.8147 0.99 0.908,1.08 565 5640 0.9977 1.0 0.909,1.1 458 4552
516.1 Hemoptysis respiratory Both 0.8892 0.993 0.904,1.09 473 4720 0.9977 1.0 0.909,1.1 458 4552
519 Other diseases of respiratory system, not elsewhere classified respiratory Both 0.5383 1.01 0.98,1.04 5153 32053 0.9506 0.999 0.966,1.03 3820 28292
519.1 Tracheostomy complications respiratory Both 0.2158 1.1 0.945,1.28 176 1760 0.3319 1.08 0.925,1.26 173 1703
519.2 Respiratory complications respiratory Both 0.2965 0.945 0.849,1.05 370 3696 0.3972 0.954 0.856,1.06 357 3581
519.8 Other diseases of respiratory system, NEC respiratory Both 0.9141 1.0 0.937,1.08 887 8857 0.9183 0.996 0.929,1.07 861 8601
519.9 Symptoms involving respiratory system and other chest symptoms respiratory Both 0.7943 1.0 0.972,1.04 4043 29199 0.9506 0.999 0.966,1.03 3820 28292
520 Disorders of tooth development digestive Both 0.5152 1.04 0.924,1.17 291 2900 0.5929 1.04 0.893,1.22 170 1655
520.1 Hereditary disturbances in tooth structure digestive Both 0.4775 1.07 0.894,1.27 131 1301 0.4365 1.07 0.899,1.28 130 1247
520.2 Disturbances in tooth eruption digestive Both 0.6194 1.04 0.891,1.22 172 1693 0.5929 1.04 0.893,1.22 170 1655
521 Diseases of hard tissues of teeth digestive Both 0.9036 1.0 0.931,1.08 719 7167 0.9333 1.0 0.927,1.09 653 6494
521.1 Dental caries digestive Both 0.8222 1.01 0.933,1.09 673 6709 0.9333 1.0 0.927,1.09 653 6494
522 Diseases of pulp and periapical tissues digestive Both 0.06607 1.1 0.994,1.21 408 4067 0.4624 1.04 0.933,1.17 329 3297
522.5 Periapical abscess digestive Both 0.3622 1.05 0.943,1.17 341 3404 0.4624 1.04 0.933,1.17 329 3297
523 Gingival and periodontal diseases digestive Both 0.1687 1.06 0.975,1.16 569 5690 0.4775 1.08 0.877,1.32 100 988
523.1 Gingivitis digestive Both 0.7194 1.04 0.857,1.25 117 1163 0.8017 1.02 0.847,1.24 116 1126
523.3 Periodontitis (acute or chronic) digestive Both 0.597 1.03 0.917,1.16 294 2940 0.4775 1.08 0.877,1.32 100 988
523.31 Acute periodontitis digestive Both 0.5297 1.04 0.916,1.19 251 2510 0.5585 1.04 0.911,1.19 239 2432
523.32 Chronic periodontitis digestive Both 0.5358 1.07 0.871,1.31 103 1030 0.4775 1.08 0.877,1.32 100 988
524 Dentofacial anomalies, including malocclusion digestive Both 0.2938 1.07 0.947,1.2 308 3080 0.2661 1.09 0.935,1.27 186 1816
524.3 Anomalies of tooth position/malocclusion digestive Both 0.2559 1.09 0.937,1.28 186 1856 0.2661 1.09 0.935,1.27 186 1816
525 Other diseases of the teeth and supporting structures digestive Both 0.9954 1.0 0.933,1.07 853 8530 0.3811 0.95 0.847,1.07 310 3063
525.1 Loss of teeth or edentulism digestive Both 0.3304 0.945 0.843,1.06 318 3178 0.3811 0.95 0.847,1.07 310 3063
526 Diseases of the jaws digestive Both 0.5023 0.985 0.942,1.03 2140 21162 0.0871 0.914 0.824,1.01 388 3853
526.1 Cysts of the jaws digestive Both 0.2667 0.925 0.805,1.06 213 2123 0.195 0.911 0.792,1.05 207 2056
526.3 Anomalies of jaw size/symmetry digestive Both 0.2328 1.09 0.946,1.25 206 2052 0.241 1.09 0.945,1.25 206 2021
526.4 Temporomandibular joint disorders digestive Both 0.7745 0.991 0.934,1.05 1178 11779 0.5929 1.02 0.941,1.11 588 5852
526.41 Temporomandibular joint disorder, unspecified digestive Both 0.6194 1.02 0.951,1.09 941 9410 0.5781 1.02 0.953,1.09 927 9133
526.42 Arthralgia/ankylosis of temporomandibular joint digestive Both 0.6745 1.02 0.937,1.11 600 5993 0.5929 1.02 0.941,1.11 588 5852
526.5 Inflammatory conditions of jaw digestive Both 0.3214 0.936 0.821,1.07 242 2405 0.2415 0.924 0.809,1.05 235 2327
526.9 Jaw disease NOS digestive Both 0.07244 0.911 0.823,1.01 399 3982 0.0871 0.914 0.824,1.01 388 3853
527 Diseases of the salivary glands digestive Both 0.4295 0.978 0.925,1.03 1362 13604 0.6622 0.968 0.834,1.12 190 1885
527.2 Sialoadenitis digestive Both 0.3698 0.949 0.846,1.06 320 3200 0.4055 0.952 0.847,1.07 311 3102
527.7 Disturbance of salivary secretion digestive Both 0.8551 0.993 0.921,1.07 715 7141 0.8551 0.993 0.92,1.07 695 6873
527.8 Other specified diseases of the salivary glands digestive Both 0.6281 0.965 0.833,1.12 196 1960 0.6622 0.968 0.834,1.12 190 1885
528 Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue digestive Both 0.07943 0.96 0.918,1.0 2077 20750 0.3963 0.925 0.772,1.11 130 1279
528.1 Stomatitis and mucositis digestive Both 0.2838 0.953 0.872,1.04 536 5360 0.3589 0.929 0.794,1.09 167 1655
528.11 Stomatitis and mucositis (ulcerative) digestive Both 0.1045 0.876 0.746,1.03 165 1650 0.1393 0.884 0.75,1.04 158 1596
528.12 Oral aphthae digestive Both 0.4688 0.944 0.808,1.1 170 1700 0.3589 0.929 0.794,1.09 167 1655
528.3 Cellulitis and abscess of oral soft tissues digestive Both 0.3266 0.927 0.797,1.08 185 1837 0.2606 0.916 0.785,1.07 180 1782
528.4 Cysts of oral soft tissues digestive Both 0.2564 1.12 0.922,1.35 110 1096 0.1045 1.22 0.959,1.56 65 656
528.41 Cyst of the salivary gland digestive Both 0.1334 1.2 0.946,1.53 68 679 0.1045 1.22 0.959,1.56 65 656
528.5 Diseases of lips digestive Both 0.9183 0.994 0.891,1.11 334 3340 0.6622 0.975 0.872,1.09 319 3224
528.6 Leukoplakia of oral mucosa digestive Both 0.5754 0.948 0.788,1.14 113 1120 0.7362 0.968 0.803,1.17 110 1070
528.7 Sialolithiasis digestive Both 0.3069 0.911 0.762,1.09 132 1320 0.3963 0.925 0.772,1.11 130 1279
529 Diseases and other conditions of the tongue digestive Both 0.4508 0.967 0.885,1.06 541 5402 0.3148 1.09 0.919,1.3 132 1307
529.1 Glossitis digestive Both 0.1138 0.845 0.687,1.04 99 982 0.1552 0.857 0.692,1.06 95 938
529.6 Glossodynia digestive Both 0.4864 1.06 0.895,1.26 136 1355 0.3148 1.09 0.919,1.3 132 1307
530 Diseases of esophagus digestive Both 0.5224 0.993 0.972,1.01 13874 23034 0.0537 0.941 0.885,1.0 1137 11592
530.1 Esophagitis, GERD and related diseases digestive Both 0.5236 0.993 0.972,1.01 13419 23031 0.5248 0.946 0.796,1.12 143 1409
530.11 GERD digestive Both 0.5236 0.993 0.971,1.01 13059 23031 0.6823 0.995 0.973,1.02 12526 22452
530.12 Ulcer of esophagus digestive Both 0.5689 0.965 0.855,1.09 298 2973 0.4977 0.958 0.845,1.09 277 2885
530.13 Barrett's esophagus digestive Both 0.6012 1.02 0.94,1.11 609 6080 0.9162 1.0 0.922,1.09 571 5876
530.14 Reflux esophagitis digestive Both 0.9886 1.0 0.948,1.06 1483 14213 0.912 1.0 0.949,1.06 1402 13774
530.15 Eosinophilic esophagitis digestive Both 0.4295 0.933 0.787,1.11 145 1441 0.5248 0.946 0.796,1.12 143 1409
530.2 Esophageal bleeding (varices/hemorrhage) digestive Both 0.3273 0.953 0.864,1.05 475 4742 0.3581 0.954 0.862,1.05 442 4596
530.3 Stricture and stenosis of esophagus digestive Both 0.4571 0.972 0.901,1.05 752 7474 0.5559 0.977 0.904,1.06 718 7237
530.5 Disorders of esophageal motility digestive Both 0.631 0.976 0.882,1.08 434 4326 0.6637 0.978 0.882,1.08 420 4196
530.6 Diverticulum of esophagus, acquired digestive Both 0.2198 1.12 0.933,1.35 121 1181 0.195 1.13 0.939,1.36 120 1127
530.7 Gastroesophageal laceration-hemorrhage syndrome digestive Both 0.7047 0.955 0.752,1.21 70 700 0.9462 1.01 0.789,1.29 66 677
530.9 Heartburn digestive Both 0.03981 0.939 0.885,0.997 1198 11946 0.0537 0.941 0.885,1.0 1137 11592
531 Peptic ulcer (excl. esophageal) digestive Both 0.3228 0.974 0.926,1.03 1608 16066 0.8414 0.98 0.804,1.19 106 1105
531.1 Hemorrhage from gastrointestinal ulcer digestive Both 0.9727 0.998 0.888,1.12 311 3103 0.863 0.989 0.877,1.12 290 3000
531.2 Gastric ulcer digestive Both 0.5834 0.981 0.915,1.05 884 8834 0.5929 0.981 0.913,1.05 831 8562
531.3 Duodenal ulcer digestive Both 0.9057 1.01 0.905,1.12 362 3613 0.9661 1.0 0.897,1.12 332 3492
531.4 Peptic ulcer, site unspecified digestive Both 0.8892 0.994 0.915,1.08 632 6313 0.8551 0.992 0.911,1.08 600 6093
531.5 Gastrojejunal ulcer digestive Both 0.6109 0.952 0.787,1.15 115 1143 0.8414 0.98 0.804,1.19 106 1105
532 Dysphagia digestive Both 0.7852 0.995 0.963,1.03 4457 22190 0.7656 0.995 0.962,1.03 4286 21611
535 Gastritis and duodenitis digestive Both 0.1164 0.965 0.923,1.01 2129 21208 0.6501 0.984 0.92,1.05 936 9544
535.1 Acute gastritis digestive Both 0.8492 0.993 0.924,1.07 814 8139 0.7621 0.989 0.918,1.06 776 7903
535.2 Atrophic gastritis digestive Both 0.7345 0.978 0.859,1.11 250 2500 0.867 0.989 0.865,1.13 234 2418
535.6 Duodenitis digestive Both 0.4645 0.955 0.844,1.08 265 2650 0.5224 0.959 0.844,1.09 245 2572
535.8 Other specified gastritis digestive Both 0.0309 0.904 0.825,0.991 497 4964 0.04266 0.907 0.825,0.997 464 4800
535.9 Gastritis and duodenitis, NOS digestive Both 0.6209 0.983 0.921,1.05 985 9835 0.6501 0.984 0.92,1.05 936 9544
536 Disorders of function of stomach digestive Both 0.4539 1.02 0.973,1.06 2251 22311 0.3055 1.03 0.976,1.08 1597 16341
536.3 Gastroparesis digestive Both 0.8375 0.99 0.902,1.09 489 4876 0.5346 0.97 0.88,1.07 455 4755
536.7 Complications of gastrostomy, colostomy and enterostomy digestive Both 0.975 1.0 0.895,1.12 334 3331 0.8395 1.01 0.898,1.14 294 3228
536.8 Dyspepsia and other specified disorders of function of stomach digestive Both 0.3926 1.02 0.972,1.07 1699 16834 0.3055 1.03 0.976,1.08 1597 16341
537 Other disorders of stomach and duodenum digestive Both 0.7211 0.992 0.951,1.04 2357 23199 0.4169 1.08 0.896,1.3 119 1225
537.1 Lesions of stomach and duodenum digestive Both 0.4753 1.07 0.892,1.28 128 1271 0.4169 1.08 0.896,1.3 119 1225
539 Bariatric surgery digestive Both 0.3192 0.969 0.912,1.03 1118 11180 0.271 0.966 0.908,1.03 1087 10863
540 Appendiceal conditions digestive Both 0.4018 1.05 0.943,1.16 399 3990 0.6039 1.03 0.913,1.17 271 2845
540.1 Appendicitis digestive Both 0.2518 1.07 0.955,1.19 349 3490 0.6039 1.03 0.913,1.17 271 2845
540.11 Acute appendicitis digestive Both 0.4315 1.05 0.931,1.18 293 2930 0.6039 1.03 0.913,1.17 271 2845
550 Abdominal hernia digestive Both 0.07586 0.974 0.946,1.0 5517 31191 0.6295 0.984 0.922,1.05 986 10648
550.1 Inguinal hernia digestive Both 0.2265 0.967 0.915,1.02 1427 13556 0.1995 0.964 0.912,1.02 1364 13125
550.2 Diaphragmatic hernia digestive Both 0.0955 0.964 0.923,1.01 2290 21266 0.1112 0.965 0.923,1.01 2161 20611
550.3 Femoral hernia digestive Both 0.4645 0.931 0.769,1.13 109 1082 0.2793 0.898 0.739,1.09 105 1055
550.4 Umbilical hernia digestive Both 0.05129 0.939 0.882,1.0 1053 10514 0.1 0.947 0.887,1.01 995 10196
550.5 Ventral hernia digestive Both 0.114 0.962 0.917,1.01 1826 18190 0.1483 0.963 0.916,1.01 1651 17580
550.6 Incisional hernia digestive Both 0.5902 0.983 0.924,1.05 1101 10999 0.6295 0.984 0.922,1.05 986 10648
555 Inflammatory bowel disease and other gastroenteritis and colitis digestive Both 0.8185 1.01 0.95,1.07 1275 12527 0.6982 0.98 0.885,1.09 413 4311
555.1 Regional enteritis digestive Both 0.7499 1.01 0.94,1.09 775 7701 0.7727 1.01 0.938,1.09 729 7613
555.2 Ulcerative colitis digestive Both 0.8872 0.995 0.924,1.07 768 7591 0.6982 0.98 0.885,1.09 413 4311
555.21 Ulcerative colitis (chronic) digestive Both 0.8892 0.993 0.899,1.1 438 4361 0.6982 0.98 0.885,1.09 413 4311
556 Ulceration of the lower GI tract digestive Both 0.2307 1.06 0.964,1.16 473 4719 0.3776 1.08 0.91,1.28 139 1460
556.1 Ulceration of intestine digestive Both 0.5105 1.03 0.935,1.15 412 4099 0.3776 1.08 0.91,1.28 139 1460
556.11 Angiodysplasia of intestine (without mention of hemorrhage) digestive Both 0.3999 1.07 0.909,1.27 152 1496 0.3776 1.08 0.91,1.28 139 1460
557 Intestinal malabsorption (non-celiac) digestive Both 0.5702 1.02 0.96,1.08 1306 12565 0.7674 0.982 0.872,1.11 300 3012
557.1 Celiac disease digestive Both 0.7907 0.984 0.874,1.11 305 3050 0.7674 0.982 0.872,1.11 300 3012
558 Noninfectious gastroenteritis digestive Both 0.1507 1.03 0.989,1.07 2706 20417 0.1531 1.03 0.989,1.07 2519 20139
559 Ileostomy status digestive Both 0.1959 1.05 0.976,1.13 773 7702 0.4571 1.03 0.95,1.12 594 7576
560 Intestinal obstruction without mention of hernia digestive Both 0.8831 1.0 0.963,1.05 2580 20303 0.9727 1.0 0.945,1.06 1287 14146
560.1 Paralytic ileus digestive Both 0.6622 0.988 0.936,1.04 1429 13524 0.6252 0.986 0.93,1.04 1245 13292
560.2 Impaction of intestine digestive Both 0.8222 0.986 0.87,1.12 257 2499 0.8974 0.992 0.872,1.13 243 2455
560.3 Peritoneal or intestinal adhesions digestive Both 0.0955 0.897 0.789,1.02 261 2599 0.07244 0.879 0.763,1.01 212 2550
560.4 Other intestinal obstruction digestive Both 0.3499 1.03 0.972,1.08 1489 14381 0.9727 1.0 0.945,1.06 1287 14146
561 Symptoms involving digestive system digestive Both 0.7656 1.0 0.978,1.03 7750 22039 0.984 1.0 0.957,1.05 2209 18718
561.1 Diarrhea digestive Both 0.7762 1.0 0.976,1.03 5986 22042 0.865 1.0 0.973,1.03 5596 21736
561.2 Flatulence digestive Both 0.9886 1.0 0.958,1.04 2358 18995 0.984 1.0 0.957,1.05 2209 18718
562 Diverticulosis and diverticulitis digestive Both 0.4775 1.01 0.98,1.04 5014 18500 0.1002 1.05 0.991,1.11 1224 12026
562.1 Diverticulosis digestive Both 0.5623 1.01 0.978,1.04 4973 18448 0.7691 1.0 0.972,1.04 4690 18146
562.2 Diverticulitis digestive Both 0.1524 1.04 0.985,1.1 1292 12242 0.1002 1.05 0.991,1.11 1224 12026
563 Constipation digestive Both 0.8017 0.996 0.967,1.03 5639 22004 0.5508 0.991 0.961,1.02 5343 21698
564 Functional digestive disorders digestive Both 0.9057 1.0 0.977,1.03 9553 22037 0.335 0.975 0.927,1.03 1643 16263
564.1 Irritable Bowel Syndrome digestive Both 0.3319 1.02 0.98,1.06 2751 17147 0.4656 1.02 0.974,1.06 2639 16915
564.8 Abnormal findings on exam of gastrointestinal tract/ abdominal area digestive Both 0.9247 1.0 0.96,1.05 2348 18710 0.9247 0.998 0.954,1.04 2139 18425
564.9 Personal history of diseases of digestive system digestive Both 0.5117 0.984 0.936,1.03 1762 16521 0.335 0.975 0.927,1.03 1643 16263
565 Anal and rectal conditions digestive Both 0.3622 1.02 0.978,1.06 2533 24500 0.9099 1.0 0.935,1.08 823 9140
565.1 Anal and rectal polyp digestive Both 0.6668 1.01 0.949,1.09 932 9300 0.9099 1.0 0.935,1.08 823 9140
567 Peritonitis and retroperitoneal infections digestive Both 0.8954 1.0 0.945,1.07 1149 11482 0.5224 0.979 0.918,1.04 1006 11309
568 Other disorders of peritoneum digestive Both 0.3334 1.03 0.973,1.08 1452 14494 0.4159 1.03 0.961,1.1 913 10576
568.1 Peritoneal adhesions (postoperative) (postinfection) digestive Both 0.1528 1.05 0.983,1.11 1076 10752 0.4159 1.03 0.961,1.1 913 10576
569 Other disorders of intestine digestive Both 0.1871 1.02 0.991,1.05 6343 29512 0.3631 0.971 0.912,1.03 1041 11884
569.1 Toxic gastroenteritis and colitis digestive Both 0.399 0.947 0.833,1.08 251 2510 0.7638 0.98 0.857,1.12 222 2469
569.2 Gastrointestinal complications digestive Both 0.6501 0.986 0.93,1.05 1206 12058 0.3631 0.971 0.912,1.03 1041 11884
571 Chronic liver disease and cirrhosis digestive Both 0.7413 1.01 0.971,1.04 3603 27394 0.859 1.01 0.91,1.12 401 4302
571.5 Other chronic nonalcoholic liver disease digestive Both 0.9397 1.0 0.966,1.04 3388 27100 0.8892 1.01 0.931,1.09 734 7642
571.51 Cirrhosis of liver without mention of alcohol digestive Both 0.7638 1.01 0.939,1.09 781 7802 0.8892 1.01 0.931,1.09 734 7642
571.6 Primary biliary cirrhosis digestive Both 0.7998 0.978 0.827,1.16 146 1460 0.879 0.987 0.829,1.17 136 1429
571.8 Liver abscess and sequelae of chronic liver disease digestive Both 0.7834 1.01 0.938,1.09 749 7472 0.859 1.01 0.91,1.12 401 4302
571.81 Portal hypertension digestive Both 0.8356 1.01 0.915,1.12 441 4400 0.859 1.01 0.91,1.12 401 4302
572 Ascites (non malignant) digestive Both 0.6324 1.01 0.965,1.06 1884 18805 0.7047 1.01 0.961,1.06 1680 18371
573 Other disorders of liver digestive Both 0.456 1.01 0.981,1.04 4460 28151 0.0955 1.03 0.994,1.07 3178 27457
573.1 Chronic passive congestion of liver digestive Both 0.1282 1.17 0.956,1.43 100 991 0.195 1.14 0.933,1.4 96 970
573.2 Liver replaced by transplant digestive Both 0.4436 0.948 0.827,1.09 227 2268 0.4864 0.951 0.827,1.09 214 2219
573.3 Hepatomegaly digestive Both 0.4074 0.955 0.855,1.07 337 3368 0.3819 0.949 0.844,1.07 294 3294
573.4 Acute and subacute necrosis of liver digestive Both 0.798 1.02 0.898,1.15 258 2580 0.9354 1.01 0.882,1.15 229 2523
573.5 Jaundice (not of newborn) digestive Both 0.9247 0.996 0.925,1.07 758 7555 0.8147 0.991 0.917,1.07 688 7376
573.6 Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH] digestive Both 0.3214 1.02 0.977,1.07 1973 19683 0.1941 1.03 0.984,1.08 1882 19233
573.7 Abnormal results of function study of liver digestive Both 0.7907 0.994 0.95,1.04 2110 21014 0.7079 0.991 0.947,1.04 1987 20536
573.9 Abnormal serum enzyme levels digestive Both 0.175 1.03 0.989,1.06 3345 28043 0.0955 1.03 0.994,1.07 3178 27457
574 Cholelithiasis and cholecystitis digestive Both 0.9397 0.998 0.959,1.04 2610 25589 0.8872 0.994 0.916,1.08 635 6458
574.1 Cholelithiasis digestive Both 0.6471 0.99 0.949,1.03 2391 23829 0.7674 0.985 0.891,1.09 427 4310
574.11 Cholelithiasis with acute cholecystitis digestive Both 0.7145 0.976 0.859,1.11 260 2580 0.9397 0.995 0.872,1.14 245 2487
574.12 Cholelithiasis with other cholecystitis digestive Both 0.6871 0.98 0.889,1.08 444 4434 0.7674 0.985 0.891,1.09 427 4310
574.2 Calculus of bile duct digestive Both 0.8472 1.01 0.932,1.09 696 6939 0.6353 1.02 0.941,1.1 658 6768
574.3 Cholecystitis without cholelithiasis digestive Both 0.9376 0.997 0.92,1.08 667 6662 0.8872 0.994 0.916,1.08 635 6458
575 Other biliary tract disease digestive Both 0.2911 0.975 0.929,1.02 1868 18668 0.2559 1.09 0.938,1.27 176 1824
575.1 Cholangitis digestive Both 0.9484 0.996 0.888,1.12 310 3089 0.5297 0.962 0.851,1.09 273 2990
575.2 Obstruction of bile duct digestive Both 0.4634 0.967 0.884,1.06 530 5291 0.4036 0.961 0.874,1.06 480 5117
575.6 Cholesterolosis of gallbladder digestive Both 0.335 0.924 0.787,1.08 168 1680 0.3614 0.926 0.785,1.09 159 1647
575.7 Other disorders of gallbladder digestive Both 0.6776 0.984 0.914,1.06 773 7719 0.7015 0.985 0.912,1.06 726 7492
575.8 Other disorders of biliary tract digestive Both 0.2466 0.962 0.901,1.03 996 9950 0.175 0.954 0.89,1.02 901 9656
575.9 Nonspecific abnormal findings on radiological and other examination of biliary tract digestive Both 0.375 1.07 0.922,1.24 188 1880 0.2559 1.09 0.938,1.27 176 1824
577 Diseases of pancreas digestive Both 0.04467 0.952 0.908,0.999 1842 18379 0.877 0.992 0.9,1.09 436 4376
577.1 Acute pancreatitis digestive Both 0.01413 0.921 0.862,0.984 967 9651 0.02188 0.923 0.863,0.989 909 9347
577.2 Chronic pancreatitis digestive Both 0.03388 0.893 0.804,0.992 396 3955 0.03548 0.891 0.8,0.992 373 3831
577.3 Cyst and pseudocyst of pancreas digestive Both 0.6998 0.981 0.892,1.08 462 4557 0.877 0.992 0.9,1.09 436 4376
578 Gastrointestinal hemorrhage digestive Both 0.3062 1.02 0.984,1.05 3572 30460 0.2291 1.04 0.977,1.1 1136 11966
578.1 Hematemesis digestive Both 0.9886 0.999 0.901,1.11 383 3821 0.9661 0.998 0.897,1.11 360 3727
578.2 Blood in stool digestive Both 0.175 1.03 0.986,1.08 2156 21196 0.1803 1.03 0.986,1.08 1981 20673
578.8 Hemorrhage of rectum and anus digestive Both 0.4842 1.02 0.969,1.07 1718 17070 0.5395 1.02 0.965,1.07 1558 16664
578.9 Hemorrhage of gastrointestinal tract digestive Both 0.2831 1.03 0.974,1.09 1238 12280 0.2291 1.04 0.977,1.1 1136 11966
579 Other symptoms involving abdomen and pelvis digestive Both 0.9311 1.0 0.968,1.04 3750 28690 0.6577 1.02 0.949,1.09 924 9610
579.2 Splenomegaly digestive Both 0.3631 1.04 0.956,1.13 593 5923 0.7211 1.02 0.931,1.11 549 5806
579.8 Nonspecific abnormal findings in stool contents digestive Both 0.8872 1.0 0.941,1.07 998 9882 0.6577 1.02 0.949,1.09 924 9610
580 Nephritis; nephrosis; renal sclerosis genitourinary Both 0.09772 0.953 0.899,1.01 1264 12626 0.5888 1.04 0.913,1.17 265 2673
580.1 Glomerulonephritis genitourinary Both 0.6152 0.972 0.869,1.09 324 3228 0.4188 1.06 0.924,1.21 225 2232
580.11 Proliferative glomerulonephritis genitourinary Both 0.5623 1.06 0.874,1.28 114 1140 0.4169 1.09 0.89,1.32 106 1103
580.12 Non-proliferative glomerulonephritis genitourinary Both 0.4797 0.927 0.75,1.14 92 905 0.6855 0.956 0.77,1.19 87 881
580.14 Chronic glomerulonephritis, NOS genitourinary Both 0.6237 1.03 0.905,1.18 232 2298 0.4188 1.06 0.924,1.21 225 2232
580.2 Nephrotic syndrome without mention of glomerulonephritis genitourinary Both 0.7396 1.03 0.877,1.2 167 1670 0.278 1.09 0.93,1.29 156 1623
580.3 Nephritis and nephropathy without mention of glomerulonephritis genitourinary Both 0.1349 0.95 0.889,1.02 943 9430 0.9376 1.0 0.914,1.1 475 4871
580.31 Nephritis and nephropathy in diseases classified elsewhere genitourinary Both 0.1086 0.931 0.853,1.02 554 5535 0.1545 0.937 0.857,1.02 528 5388
580.32 Nephritis and nephropathy with pathological lesion genitourinary Both 0.881 0.993 0.906,1.09 500 4995 0.9376 1.0 0.914,1.1 475 4871
580.4 Renal sclerosis, NOS genitourinary Both 0.3664 1.06 0.936,1.2 275 2750 0.5888 1.04 0.913,1.17 265 2673
585 Renal failure genitourinary Both 0.2767 0.984 0.956,1.01 5756 27307 0.912 1.0 0.934,1.08 804 8134
585.1 Acute renal failure genitourinary Both 0.6152 0.991 0.955,1.03 3278 22851 0.6457 0.991 0.954,1.03 3040 22220
585.2 Renal failure NOS genitourinary Both 0.5649 1.02 0.946,1.11 688 6872 0.6546 1.02 0.939,1.1 651 6671
585.3 Chronic renal failure [CKD] genitourinary Both 0.05888 0.968 0.937,1.0 4216 24655 0.8892 1.01 0.929,1.09 665 6840
585.31 Renal dialysis genitourinary Both 0.5768 0.975 0.893,1.06 543 5430 0.871 0.993 0.907,1.09 516 5285
585.32 End stage renal disease genitourinary Both 0.4624 0.973 0.904,1.05 773 7730 0.5333 0.976 0.906,1.05 732 7530
585.33 Chronic Kidney Disease, Stage III genitourinary Both 0.03548 0.954 0.913,0.997 2272 17155 0.05888 0.957 0.915,1.0 2150 16625
585.34 Chronic Kidney Disease, Stage IV genitourinary Both 0.9977 1.0 0.926,1.08 707 7038 0.8892 1.01 0.929,1.09 665 6840
585.4 Chronic kidney disease, Stage I or II genitourinary Both 0.869 0.994 0.927,1.07 851 8381 0.912 1.0 0.934,1.08 804 8134
586 Other disorders of the kidney and ureters genitourinary Both 0.877 0.998 0.97,1.03 6202 28774 0.456 0.98 0.928,1.03 1421 14255
586.1 Anatomical abnormatilies of kidney and ureters genitourinary Both 0.6546 1.03 0.91,1.16 284 2825 0.5754 1.06 0.872,1.28 110 1093
586.11 Small kidney genitourinary Both 0.3141 1.08 0.926,1.27 165 1642 0.4875 1.06 0.902,1.24 160 1592
586.12 Vesicoureteral reflux genitourinary Both 0.5058 1.07 0.882,1.29 112 1120 0.5754 1.06 0.872,1.28 110 1093
586.2 Cyst of kidney, acquired genitourinary Both 0.8035 0.992 0.935,1.05 1170 11069 0.6776 0.987 0.928,1.05 1102 10705
586.3 Vascular disorders of kidney/hypertrophy genitourinary Both 0.0871 0.863 0.729,1.02 148 1470 0.04571 0.838 0.704,0.997 140 1433
586.4 Stricture/obstruction of ureter genitourinary Both 0.6109 0.986 0.936,1.04 1536 14675 0.456 0.98 0.928,1.03 1421 14255
587 Kidney replaced by transpant genitourinary Both 0.9908 0.999 0.919,1.09 612 6120 0.7889 1.01 0.929,1.1 576 5960
588 Disorders resulting from impaired renal function genitourinary Both 0.5728 0.978 0.906,1.06 701 7004 0.3327 0.956 0.872,1.05 492 5099
588.1 Renal osteodystrophy genitourinary Both 0.4335 1.06 0.922,1.21 227 2267 0.3396 1.07 0.931,1.23 213 2219
588.2 Secondary hyperparathyroidism (of renal origin) genitourinary Both 0.4102 0.963 0.881,1.05 525 5241 0.3327 0.956 0.872,1.05 492 5099
589 Abnormal results of function study of kidney genitourinary Both 0.7261 0.987 0.92,1.06 840 8370 0.8531 0.993 0.923,1.07 779 8115
590 Pyelonephritis genitourinary Both 0.7228 0.989 0.932,1.05 1161 11597 0.875 0.995 0.936,1.06 1100 11297
591 Urinary tract infection genitourinary Both 0.6053 0.993 0.968,1.02 8020 27291 0.7379 0.996 0.97,1.02 7653 26553
592 Cystitis and urethritis genitourinary Both 0.9506 0.999 0.956,1.04 2264 19423 0.1334 0.875 0.735,1.04 141 1406
592.1 Cystitis genitourinary Both 0.9506 1.0 0.957,1.05 2149 18531 0.02455 0.882 0.791,0.984 348 3449
592.11 Acute cystitis genitourinary Both 0.8492 0.994 0.938,1.05 1256 12111 0.9226 0.997 0.939,1.06 1186 11750
592.12 Chronic cystitis genitourinary Both 0.2884 1.08 0.936,1.25 199 1972 0.3119 1.08 0.931,1.25 190 1919
592.13 Chronic interstitial cystitis genitourinary Both 0.01549 0.875 0.784,0.975 354 3540 0.02455 0.882 0.791,0.984 348 3449
592.2 Urethritis and urethral syndrome genitourinary Both 0.0955 0.863 0.726,1.03 143 1430 0.1334 0.875 0.735,1.04 141 1406
593 Hematuria genitourinary Both 0.8851 0.997 0.964,1.03 3848 26566 0.7889 0.989 0.915,1.07 695 7011
593.1 Gross hematuria genitourinary Both 0.3048 1.03 0.972,1.09 1201 11351 0.2938 1.03 0.972,1.1 1130 10978
593.2 Microscopic hematuria genitourinary Both 0.8337 0.992 0.919,1.07 724 7225 0.7889 0.989 0.915,1.07 695 7011
594 Urinary calculus genitourinary Both 0.871 1.0 0.974,1.03 5516 31876 0.1888 0.92 0.812,1.04 273 2780
594.1 Calculus of kidney genitourinary Both 0.7278 1.01 0.976,1.04 5155 31730 0.8851 1.0 0.973,1.03 4962 30814
594.2 Calculus of lower urinary tract genitourinary Both 0.3548 1.06 0.94,1.19 310 3068 0.6152 1.03 0.915,1.16 299 2961
594.3 Calculus of ureter genitourinary Both 0.2858 1.03 0.972,1.1 1104 11000 0.2506 1.04 0.974,1.11 1065 10640
594.8 Renal colic genitourinary Both 0.257 0.932 0.825,1.05 286 2851 0.1888 0.92 0.812,1.04 273 2780
595 Hydronephrosis genitourinary Both 0.2944 1.03 0.975,1.09 1410 14092 0.5781 1.02 0.96,1.08 1298 13630
596 Other disorders of bladder genitourinary Both 0.5117 0.986 0.947,1.03 2527 23338 0.6081 0.985 0.93,1.04 1303 13178
596.1 Bladder neck obstruction genitourinary Both 0.975 0.998 0.891,1.12 333 3288 0.9376 1.0 0.894,1.13 315 3145
596.5 Functional disorders of bladder genitourinary Both 0.5534 0.983 0.93,1.04 1368 13608 0.6081 0.985 0.93,1.04 1303 13178
597 Other disorders of urethra and urinary tract genitourinary Both 0.3273 0.969 0.909,1.03 1041 10322 0.9441 1.01 0.854,1.19 154 1522
597.1 Urethral stricture (not specified as infectious) genitourinary Both 0.9908 1.0 0.92,1.09 608 6024 0.9931 1.0 0.918,1.09 576 5816
597.2 Urinary complications NEC genitourinary Both 0.3388 0.966 0.901,1.04 861 8600 0.1288 0.945 0.879,1.02 789 8315
597.8 Urethral hypermobility/ISD genitourinary Both 0.8091 1.02 0.868,1.2 158 1578 0.9441 1.01 0.854,1.19 154 1522
598 Abnormal findings on examination of urine genitourinary Both 0.1888 0.962 0.907,1.02 1263 12596 0.2723 0.967 0.91,1.03 1161 11875
598.4 Other cells and casts in urine genitourinary Both 0.317 1.11 0.901,1.38 91 906 0.2512 1.13 0.915,1.41 88 871
598.9 Other nonspecific findings on examination of urine genitourinary Both 0.1312 0.956 0.901,1.01 1234 12317 0.2723 0.967 0.91,1.03 1161 11875
599 Other symptoms/disorders or the urinary system genitourinary Both 0.8492 1.0 0.98,1.03 11346 25364 0.9772 1.0 0.958,1.05 2249 19726
599.1 Urinary obstruction genitourinary Both 0.955 0.998 0.915,1.09 580 5634 0.778 0.987 0.903,1.08 541 5434
599.2 Retention of urine genitourinary Both 0.3741 1.02 0.982,1.05 4234 24058 0.455 1.01 0.979,1.05 4002 23447
599.3 Dysuria genitourinary Both 0.6067 1.01 0.974,1.05 3426 23180 0.3936 1.02 0.979,1.05 3274 22588
599.4 Urinary incontinence genitourinary Both 0.7998 0.996 0.964,1.03 4566 22567 0.881 0.997 0.965,1.03 4388 21968
599.5 Frequency of urination and polyuria genitourinary Both 0.3724 1.02 0.982,1.05 4277 23742 0.3141 1.02 0.984,1.05 4115 23132
599.6 Oliguria and anuria genitourinary Both 0.3963 1.04 0.95,1.14 513 5104 0.4305 1.04 0.945,1.14 475 4929
599.7 Urethral discharge genitourinary Both 0.5105 0.927 0.739,1.16 83 830 0.4487 0.913 0.722,1.16 77 806
599.8 Other symptoms involving urinary system genitourinary Both 0.9226 1.0 0.969,1.03 4366 23262 0.879 1.0 0.97,1.04 4173 22654
599.9 Other abnormality of urination genitourinary Both 0.9661 0.999 0.957,1.04 2349 20289 0.9772 1.0 0.958,1.05 2249 19726
600 Hyperplasia of prostate genitourinary Male 0.5929 1.01 0.97,1.06 3315 9437 0.6081 1.01 0.968,1.06 3146 9104
601 Inflammatory diseases of prostate genitourinary Male 0.7852 1.01 0.94,1.09 825 7745 0.005495 1.32 1.08,1.6 111 1170
601.1 Prostatitis genitourinary Male 0.6457 0.975 0.878,1.08 378 3680 0.2851 0.88 0.695,1.11 76 728
601.11 Acute prostatitis genitourinary Male 0.7244 0.963 0.781,1.19 95 933 0.9016 0.986 0.795,1.22 90 888
601.12 Chronic prostatitis genitourinary Male 0.2553 0.873 0.69,1.1 76 757 0.2851 0.88 0.695,1.11 76 728
601.3 Orchitis and epididymitis genitourinary Male 0.2793 0.936 0.831,1.05 303 3008 0.3724 0.946 0.838,1.07 290 2918
601.4 Balanoposthitis genitourinary Male 0.05888 1.22 0.992,1.5 103 1019 0.04365 1.24 1.01,1.53 100 975
601.8 Other inflammatory disorders of male genital organs genitourinary Male 0.02291 1.24 1.03,1.48 125 1226 0.005495 1.32 1.08,1.6 111 1170
602 Other disorders of prostate genitourinary Male 0.1667 0.916 0.809,1.04 277 2673 0.1445 0.91 0.803,1.03 270 2578
603 Other disorders of testis genitourinary Male 0.1109 1.1 0.979,1.23 348 3468 0.4018 1.08 0.9,1.3 124 1211
603.1 Hydrocele genitourinary Male 0.2838 1.08 0.939,1.24 229 2281 0.3034 1.08 0.935,1.24 216 2213
603.2 Spermatocele genitourinary Male 0.4656 1.07 0.892,1.29 126 1258 0.4018 1.08 0.9,1.3 124 1211
604 Disorders of penis genitourinary Male 0.9594 1.0 0.917,1.1 536 5321 0.618 0.96 0.819,1.13 168 1635
604.1 Redundant prepuce and phimosis/BXO genitourinary Male 0.9817 0.998 0.831,1.2 130 1297 1.0 1.0 0.831,1.2 128 1253
604.3 Peyronie's disease genitourinary Male 0.6745 0.967 0.826,1.13 171 1703 0.618 0.96 0.819,1.13 168 1635
605 Erectile dysfunction [ED] genitourinary Male 0.3475 1.02 0.978,1.06 2844 10666 0.342 1.02 0.978,1.07 2723 10337
608 Other disorders of male genital organs genitourinary Male 0.6887 0.988 0.933,1.05 1302 11530 0.8511 0.994 0.937,1.05 1238 11197
609 Male infertility and abnormal spermatozoa genitourinary Male 0.8091 0.986 0.881,1.1 335 3350 0.5585 0.944 0.777,1.15 113 1155
609.1 Infertility, male genitourinary Male 0.9506 0.996 0.873,1.14 242 2420 0.5754 0.938 0.748,1.17 79 781
609.11 Azoospermia and oligospermia genitourinary Male 0.5834 0.939 0.749,1.18 79 789 0.5754 0.938 0.748,1.17 79 781
609.2 Abnormal spermatozoa genitourinary Male 0.5383 0.942 0.779,1.14 119 1185 0.5585 0.944 0.777,1.15 113 1155
610 Benign mammary dysplasias genitourinary Female 0.7096 0.993 0.954,1.03 3089 13905 0.02042 0.925 0.867,0.988 995 9861
610.1 Cystic mastopathy genitourinary Female 0.1972 0.963 0.911,1.02 1361 12011 0.07244 0.948 0.895,1.0 1302 11677
610.4 Benign neoplasm of breast genitourinary Female 0.7834 0.994 0.951,1.04 2400 13828 0.5916 0.988 0.945,1.03 2323 13479
610.8 Other specified benign mammary dysplasias genitourinary Female 0.08318 0.945 0.886,1.01 1047 10149 0.02042 0.925 0.867,0.988 995 9861
611 Abnormal findings on mammogram or breast exam genitourinary Both 0.399 0.986 0.955,1.02 4952 15509 0.3899 0.983 0.944,1.02 2905 15038
611.1 Abnormal mammogram genitourinary Both 0.6823 0.993 0.958,1.03 4074 13538 0.5888 0.981 0.917,1.05 921 8843
611.11 Mammographic microcalcification genitourinary Both 0.5636 0.981 0.917,1.05 962 9131 0.5888 0.981 0.917,1.05 921 8843
611.3 Lump or mass in breast genitourinary Both 0.5212 0.987 0.949,1.03 3011 15449 0.3899 0.983 0.944,1.02 2905 15038
612 Breast conditions, congenital or relating to hormones genitourinary Both 0.5495 0.979 0.913,1.05 879 8768 0.6012 0.937 0.735,1.2 68 660
612.1 Galactorrhea genitourinary Both 0.4797 1.07 0.885,1.3 109 1083 0.631 1.05 0.862,1.28 103 1062
612.2 Hypertrophy of breast (Gynecomastia) genitourinary Both 0.798 0.99 0.914,1.07 672 6710 0.7691 0.988 0.911,1.07 659 6523
612.3 Congenital anomalies of breast genitourinary Both 0.6745 0.95 0.748,1.21 70 676 0.6012 0.937 0.735,1.2 68 660
613 Other nonmalignant breast conditions genitourinary Both 0.9441 0.999 0.962,1.04 3180 18154 0.4909 0.979 0.922,1.04 1154 11569
613.1 Inflammatory disease of breast genitourinary Both 0.3917 1.04 0.95,1.14 504 5035 0.3767 1.04 0.951,1.14 494 4909
613.5 Mastodynia genitourinary Both 0.5483 0.983 0.928,1.04 1313 12942 0.6592 0.987 0.931,1.05 1256 12581
613.7 Other signs and symptoms in breast genitourinary Both 0.811 1.01 0.935,1.09 722 7109 0.7727 1.01 0.935,1.09 692 6913
613.8 Other specified disorders of breast genitourinary Both 0.6855 1.02 0.944,1.09 800 7961 0.7568 1.01 0.94,1.09 783 7748
613.9 Breast disorder NOS genitourinary Both 0.5445 0.982 0.926,1.04 1211 11947 0.4909 0.979 0.922,1.04 1154 11569
614 Inflammatory diseases of female pelvic organs genitourinary Female 0.6124 1.01 0.971,1.05 2990 16271 0.9795 1.0 0.848,1.18 150 1578
614.1 Pelvic peritoneal adhesions, female (postoperative) (postinfection) genitourinary Female 0.7586 1.02 0.898,1.16 267 2670 0.7907 1.02 0.893,1.16 254 2610
614.3 Pelvic inflammatory disease (PID) genitourinary Female 0.02042 1.13 1.02,1.25 404 4024 0.0389 1.17 1.01,1.37 188 1928
614.31 Acute inflammatory pelvic disease genitourinary Female 0.984 1.0 0.794,1.27 74 720 1.0 1.0 0.784,1.28 68 702
614.32 Chronic inflammatory pelvic disease genitourinary Female 0.3475 1.08 0.922,1.26 167 1666 0.3516 1.08 0.918,1.27 152 1619
614.33 Pelvic inflammatory disease, NOS genitourinary Female 0.1109 1.13 0.973,1.31 198 1979 0.0389 1.17 1.01,1.37 188 1928
614.4 Inflammatory diseases of uterus, except cervix genitourinary Female 0.7362 1.03 0.862,1.23 129 1290 0.6152 1.05 0.874,1.26 126 1263
614.5 Inflammatory disease of cervix, vagina, and vulva genitourinary Female 0.984 1.0 0.958,1.04 2546 16112 0.9795 1.0 0.848,1.18 150 1578
614.51 Cervicitis and endocervicitis genitourinary Female 0.859 1.01 0.873,1.18 197 1970 0.9572 1.0 0.863,1.17 189 1919
614.52 Vaginitis and vulvovaginitis genitourinary Female 0.7709 1.01 0.962,1.05 2201 15690 0.6577 1.01 0.965,1.06 2120 15284
614.53 Cyst or abscess of Bartholin's gland genitourinary Female 0.6324 0.952 0.78,1.16 104 1040 0.7194 0.964 0.789,1.18 104 1016
614.54 Abscess or ulceration of vulva genitourinary Female 0.9354 1.01 0.857,1.18 164 1619 0.9795 1.0 0.848,1.18 150 1578
615 Endometriosis genitourinary Female 0.6412 0.986 0.932,1.04 1298 12230 0.7551 0.991 0.935,1.05 1262 11940
617 Disorders secondary to childbirth, surgery, trauma genitourinary Female 0.4467 1.02 0.967,1.08 1415 13522 0.5082 1.02 0.963,1.08 1352 13203
618 Genital prolapse genitourinary Female 0.5035 0.983 0.935,1.03 1707 14626 0.4236 0.956 0.857,1.07 350 3621
618.1 Prolapse of vaginal walls genitourinary Female 0.5164 0.98 0.924,1.04 1179 11187 0.4786 0.978 0.921,1.04 1144 10814
618.2 Uterine/Uterovaginal prolapse genitourinary Female 0.001862 1.16 1.06,1.28 444 4418 8.913E-4 1.18 1.07,1.3 437 4273
618.5 Prolapse of vaginal vault after hysterectomy genitourinary Female 0.8279 0.987 0.877,1.11 286 2855 0.9016 0.992 0.881,1.12 281 2744
618.6 Vaginal enterocele, congenital or acquired genitourinary Female 0.2999 0.945 0.85,1.05 375 3750 0.4236 0.956 0.857,1.07 350 3621
619 Noninflammatory female genital disorders genitourinary Female 0.631 1.01 0.975,1.04 4598 15534 0.8279 0.992 0.925,1.06 853 8860
619.1 Noninflammatory disorders of ovary, fallopian tube, and broad ligament genitourinary Female 0.4498 1.02 0.965,1.08 1262 11294 0.631 1.01 0.956,1.08 1211 11063
619.2 Disorders of uterus, NEC genitourinary Female 0.6871 1.02 0.925,1.12 444 4435 0.5297 1.03 0.935,1.14 431 4354
619.3 Noninflammatory disorders of cervix genitourinary Female 0.0955 0.914 0.823,1.02 391 3892 0.1099 0.917 0.824,1.02 378 3826
619.4 Noninflammatory disorders of vagina genitourinary Female 0.2344 1.03 0.981,1.08 1903 15019 0.1663 1.04 0.986,1.09 1815 14664
619.5 Noninflammatory disorders of vulva and perineum genitourinary Female 0.6223 0.983 0.919,1.05 914 9082 0.8279 0.992 0.925,1.06 853 8860
620 Dysplasia of female genital organs genitourinary Female 0.6501 1.03 0.916,1.15 325 3234 0.5546 0.948 0.792,1.13 136 1400
620.1 Dysplasia of cervix genitourinary Female 0.7311 0.97 0.814,1.16 142 1420 0.5546 0.948 0.792,1.13 136 1400
621 Endometrial hyperplasia genitourinary Female 0.7516 0.982 0.88,1.1 334 3335 0.8492 0.989 0.885,1.11 327 3229
622 Polyp of female genital organs genitourinary Female 0.14 0.956 0.901,1.01 1191 11723 0.7816 0.984 0.88,1.1 337 3385
622.1 Polyp of corpus uteri genitourinary Female 0.07586 0.942 0.881,1.01 949 9362 0.0871 0.943 0.882,1.01 923 9106
622.2 Mucous polyp of cervix genitourinary Female 0.9863 0.999 0.895,1.12 348 3480 0.7816 0.984 0.88,1.1 337 3385
623 Hypertrophy of female genital organs genitourinary Female 0.5284 0.973 0.895,1.06 605 6003 0.471 0.969 0.89,1.06 575 5856
624 Symptoms involving female genital tract genitourinary Female 0.4178 1.03 0.963,1.1 1013 9695 0.9886 1.0 0.948,1.06 1510 12556
624.1 Dystrophy of female genital tract genitourinary Female 0.2667 0.914 0.78,1.07 168 1680 0.2999 0.915 0.774,1.08 150 1616
624.9 stress incontinence, female genitourinary Female 0.9908 1.0 0.949,1.05 1549 12918 0.9886 1.0 0.948,1.06 1510 12556
625 Pain and other symptoms associated with female genital organs genitourinary Female 0.6745 0.993 0.96,1.03 4618 14394 0.9817 0.999 0.935,1.07 978 9855
625.1 Dyspareunia genitourinary Female 0.955 1.0 0.939,1.07 1011 10081 0.9817 0.999 0.935,1.07 978 9855
626 Disorders of menstruation and other abnormal bleeding from female genital tract genitourinary Female 0.5346 1.01 0.977,1.05 4726 13065 0.5902 0.977 0.898,1.06 622 5138
626.1 Irregular menstrual cycle/bleeding genitourinary Female 0.6637 1.01 0.97,1.05 3426 12112 0.9311 0.995 0.883,1.12 298 2964
626.11 Absent or infrequent menstruation genitourinary Female 0.9863 1.0 0.929,1.08 802 6948 0.8147 1.01 0.936,1.09 779 6831
626.12 Excessive or frequent menstruation genitourinary Female 0.3258 1.03 0.974,1.08 1703 9843 0.2698 1.03 0.977,1.09 1673 9634
626.13 Irregular menstrual cycle genitourinary Female 0.4864 0.981 0.929,1.04 1543 10197 0.5297 0.982 0.93,1.04 1508 9967
626.14 Irregular menstrual bleeding genitourinary Female 0.875 0.994 0.922,1.07 777 7408 0.7464 0.988 0.916,1.06 766 7277
626.15 Infertility, female, associated with anovulation genitourinary Female 0.9817 1.0 0.889,1.13 300 3000 0.9311 0.995 0.883,1.12 298 2964
626.2 Dysmenorrhea genitourinary Female 0.4487 1.02 0.962,1.09 1116 8297 0.4645 1.02 0.961,1.09 1096 8140
626.4 Premenstrual tension syndromes genitourinary Female 0.8453 0.988 0.87,1.12 275 2741 0.6745 0.973 0.856,1.11 268 2691
626.8 Infertility, female genitourinary Female 0.5598 0.975 0.897,1.06 630 5218 0.5902 0.977 0.898,1.06 622 5138
627 Menopausal and postmenopausal disorders genitourinary Female 0.3936 1.02 0.979,1.05 3657 12296 0.865 0.989 0.865,1.13 230 2287
627.1 Postmenopausal bleeding genitourinary Female 0.5495 0.98 0.917,1.05 957 8768 0.7482 0.989 0.924,1.06 922 8471
627.2 Symptomatic menopause genitourinary Female 0.1629 1.03 0.987,1.08 2443 11667 0.5047 0.96 0.85,1.08 286 2846
627.21 Symptomatic artificial menopause genitourinary Female 0.7998 0.977 0.815,1.17 125 1241 0.6808 0.962 0.799,1.16 118 1203
627.22 Need for Hormone replacement therapy (postmenopausal) genitourinary Female 0.3334 0.943 0.837,1.06 295 2948 0.5047 0.96 0.85,1.08 286 2846
627.3 Postmenopausal atrophic vaginitis genitourinary Female 0.2296 1.05 0.971,1.13 729 7262 0.118 1.06 0.984,1.15 698 7012
627.4 Premenopausal menorrhagia genitourinary Female 0.6223 1.03 0.915,1.16 305 3020 0.6353 1.03 0.913,1.16 300 2943
627.5 Premature menopause and other ovarian failure genitourinary Female 0.787 0.982 0.86,1.12 234 2340 0.865 0.989 0.865,1.13 230 2287
628 Ovarian cyst genitourinary Female 0.4083 1.02 0.97,1.08 1619 11554 0.3639 1.03 0.971,1.08 1559 11269
634 Miscarriage; stillbirth pregnancy complications Female 0.7328 1.01 0.935,1.1 648 6413 0.7516 0.965 0.776,1.2 93 925
634.1 Missed abortion/Hydatidiform mole pregnancy complications Female 0.778 0.98 0.85,1.13 209 2090 0.7834 0.98 0.849,1.13 206 2042
634.3 Ectopic pregnancy pregnancy complications Female 0.8995 1.01 0.818,1.26 95 950 0.7516 0.965 0.776,1.2 93 925
635 Hemorrhage during pregnancy; childbirth and postpartum pregnancy complications Female 0.02884 0.891 0.804,0.988 414 4070 0.04365 0.858 0.739,0.996 201 2030
635.2 Antepartum hemorrhage, abruptio placentae, and placenta previa pregnancy complications Female 0.4498 0.952 0.837,1.08 272 2720 0.4645 0.953 0.838,1.08 271 2684
635.3 Placenta previa and abruptio placenta pregnancy complications Female 0.04786 0.862 0.745,0.998 206 2060 0.04365 0.858 0.739,0.996 201 2030
636 Early or threatened labor; hemorrhage in early pregnancy pregnancy complications Female 0.7621 1.01 0.94,1.09 855 6402 0.5715 1.08 0.823,1.42 59 585
636.1 Threatened premature labor pregnancy complications Female 0.8974 1.01 0.894,1.14 298 2980 0.7762 1.02 0.902,1.15 295 2931
636.2 Early onset of delivery pregnancy complications Female 0.5117 1.05 0.912,1.2 233 2330 0.4207 1.06 0.922,1.22 231 2283
636.3 Hemorrhage in early pregnancy pregnancy complications Female 0.6776 0.977 0.874,1.09 356 3556 0.6839 0.977 0.874,1.09 352 3499
636.8 Cervical incompetence pregnancy complications Female 0.6223 1.07 0.816,1.41 60 600 0.5715 1.08 0.823,1.42 59 585
637 Short gestation; low birth weight; and fetal growth retardation pregnancy complications Both 0.7889 0.971 0.783,1.2 89 884 0.7413 0.963 0.772,1.2 84 861
638 Other high-risk pregnancy pregnancy complications Female 0.8279 0.992 0.921,1.07 818 5867 0.7962 0.99 0.919,1.07 802 5787
642 Hypertension complicating pregnancy, childbirth, and the puerperium pregnancy complications Female 0.07244 0.912 0.824,1.01 421 4210 0.1 0.888 0.771,1.02 214 2112
642.1 Preeclampsia and eclampsia pregnancy complications Female 0.07762 0.881 0.765,1.01 215 2150 0.1 0.888 0.771,1.02 214 2112
643 Excessive vomiting in pregnancy pregnancy complications Female 0.02188 0.833 0.712,0.974 181 1810 0.3999 0.909 0.728,1.13 85 858
643.1 Hyperemesis gravidarum pregnancy complications Female 0.3581 0.902 0.724,1.12 87 870 0.3999 0.909 0.728,1.13 85 858
644 Anemia during pregnancy pregnancy complications Female 0.5585 1.05 0.892,1.24 154 1540 0.542 1.05 0.892,1.24 150 1530
645 Late pregnancy and failed induction pregnancy complications Female 0.8995 0.992 0.878,1.12 286 2860 0.875 0.99 0.876,1.12 282 2822
646 Other complications of pregnancy NEC pregnancy complications Female 0.3289 0.959 0.881,1.04 622 5063 0.3342 0.959 0.88,1.04 612 4997
647 Infectious and parasitic complications affecting pregnancy pregnancy complications Female 0.004365 0.775 0.651,0.924 152 1520 0.4487 0.941 0.805,1.1 180 1801
647.1 Infections of genitourinary tract during pregnancy pregnancy complications Female 0.4295 0.939 0.804,1.1 182 1820 0.4487 0.941 0.805,1.1 180 1801
649 Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.8414 0.993 0.927,1.06 968 6387 0.1355 0.924 0.833,1.03 403 4055
649.1 Diabetes or abnormal glucose tolerance complicating pregnancy pregnancy complications Female 0.1496 0.928 0.837,1.03 413 4130 0.1355 0.924 0.833,1.03 403 4055
650 Normal delivery pregnancy complications Female 0.3972 0.968 0.897,1.04 757 6412 0.4276 0.969 0.898,1.05 744 6314
651 Multiple gestation pregnancy complications Female 0.857 0.981 0.796,1.21 100 1000 0.881 0.984 0.798,1.21 99 978
652 Malposition and malpresentation of fetus or obstruction pregnancy complications Female 0.8318 0.99 0.898,1.09 461 4586 0.8492 0.991 0.898,1.09 458 4516
653 Problems associated with amniotic cavity and membranes pregnancy complications Female 0.2735 1.06 0.957,1.17 443 4189 0.2228 1.06 0.963,1.18 439 4133
654 Other and unspecified complications of birth; puerperium affecting management of mother pregnancy complications Female 0.5534 0.972 0.885,1.07 482 4820 0.5152 1.06 0.897,1.24 162 1608
654.1 Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium pregnancy complications Female 0.1875 0.933 0.842,1.03 402 4020 0.1972 0.934 0.841,1.04 394 3956
654.2 Rhesus isoimmunization in pregnancy pregnancy complications Female 0.4989 1.06 0.899,1.24 163 1630 0.5152 1.06 0.897,1.24 162 1608
655 Known or suspected fetal abnormality affecting management of mother pregnancy complications Female 0.4797 0.978 0.921,1.04 1244 8117 0.863 1.01 0.914,1.11 447 4316
655.1 Abnormality in fetal heart rate or rhythm pregnancy complications Female 0.9886 0.999 0.906,1.1 451 4371 0.863 1.01 0.914,1.11 447 4316
656 Other perinatal conditions of fetus or newborn pregnancy complications Both 0.492 1.05 0.918,1.2 246 2460 0.01549 1.41 1.07,1.85 57 576
656.2 Respiratory conditions of fetus and newborn pregnancy complications Both 0.01148 1.42 1.08,1.86 59 590 0.01549 1.41 1.07,1.85 57 576
658 Maternal complication of pregnancy affecting fetus or newborn pregnancy complications Female 0.7145 1.03 0.887,1.19 195 1950 0.507 1.05 0.905,1.22 188 1911
661 Fetal distress and abnormal forces of labor pregnancy complications Female 0.3614 1.04 0.952,1.14 504 4732 0.4721 1.03 0.943,1.14 497 4658
663 Umbilical cord complications during labor and delivery pregnancy complications Female 0.2193 0.938 0.847,1.04 420 4080 0.2529 0.942 0.85,1.04 414 4029
665 Obstetrical/birth trauma pregnancy complications Female 0.04266 0.924 0.856,0.997 751 6161 0.05012 0.925 0.856,1.0 732 6063
669 Complications of labor and delivery NEC pregnancy complications Female 0.7129 1.02 0.936,1.1 671 5265 0.7129 1.02 0.935,1.1 662 5180
671 Venous/cerebrovascular complications embolism in pregnancy and the puerperium pregnancy complications Female 0.8279 1.02 0.872,1.19 172 1720 0.7852 1.02 0.874,1.19 168 1673
674 Other complications of the puerperium NEC pregnancy complications Female 0.6839 0.969 0.832,1.13 181 1810 0.7482 0.975 0.835,1.14 173 1782
676 Other disorders of the breast associated with childbirth and disorders of lactation pregnancy complications Female 0.5572 0.944 0.778,1.14 122 1220 0.6095 0.951 0.783,1.15 120 1201
681 Superficial cellulitis and abscess dermatologic Both 0.9204 1.0 0.972,1.03 5078 31991 0.3597 1.03 0.968,1.09 1111 12001
681.1 Cellulitis and abscess of fingers/toes dermatologic Both 0.4624 0.974 0.909,1.04 862 8581 0.369 0.968 0.902,1.04 825 8341
681.2 Cellulitis and abscess of face/neck dermatologic Both 0.5058 1.03 0.953,1.1 781 7775 0.5012 1.03 0.952,1.11 764 7562
681.3 Cellulitis and abscess of arm/hand dermatologic Both 0.6252 1.01 0.961,1.07 1533 15238 0.631 1.01 0.96,1.07 1458 14778
681.5 Cellulitis and abscess of leg, except foot dermatologic Both 0.4111 1.02 0.971,1.07 1649 16359 0.3097 1.03 0.975,1.08 1563 15859
681.6 Cellulitis and abscess of foot, toe dermatologic Both 0.561 1.02 0.961,1.08 1291 12850 0.6607 1.01 0.956,1.07 1228 12461
681.7 Cellulitis and abscess of trunk dermatologic Both 0.2296 1.04 0.978,1.1 1238 12342 0.3597 1.03 0.968,1.09 1111 12001
686 Other local infections of skin and subcutaneous tissue dermatologic Both 0.5623 1.02 0.965,1.07 1660 16466 0.3837 0.918 0.758,1.11 119 1169
686.1 Carbuncle and furuncle dermatologic Both 0.2529 1.06 0.958,1.18 390 3881 0.2404 1.06 0.959,1.18 374 3789
686.2 Impetigo dermatologic Both 0.4529 0.956 0.851,1.07 310 3068 0.3917 0.949 0.842,1.07 294 2980
686.3 Pilonidal cyst dermatologic Both 0.1722 0.879 0.73,1.06 120 1200 0.1795 0.878 0.726,1.06 114 1175
686.4 Pyogenic granuloma dermatologic Both 0.3917 0.92 0.761,1.11 121 1205 0.3837 0.918 0.758,1.11 119 1169
687 Symptoms affecting skin dermatologic Both 0.4667 1.01 0.983,1.04 6119 25901 0.9863 1.0 0.969,1.03 4777 24849
687.1 Rash and other nonspecific skin eruption dermatologic Both 0.8241 1.0 0.974,1.03 5371 25824 0.7534 1.0 0.975,1.04 5150 25086
687.2 Localized superficial swelling, mass, or lump dermatologic Both 0.4446 1.01 0.982,1.04 5264 25870 0.4207 1.01 0.982,1.04 5064 25132
687.3 Changes in skin texture dermatologic Both 0.7656 0.982 0.871,1.11 294 2926 0.7112 0.977 0.863,1.11 277 2835
687.4 Disturbance of skin sensation dermatologic Both 0.9268 0.999 0.969,1.03 4942 25586 0.9863 1.0 0.969,1.03 4777 24849
689 Disorder of skin and subcutaneous tissue NOS dermatologic Both 0.3508 0.988 0.962,1.01 7192 31086 0.2793 0.985 0.96,1.01 6869 30213
690 Erythematosquamous dermatosis dermatologic Both 0.7178 0.994 0.96,1.03 3810 26256 0.8995 0.998 0.963,1.03 3632 25348
690.1 Seborrheic dermatitis dermatologic Both 0.6966 0.993 0.96,1.03 3802 26218 0.8995 0.998 0.963,1.03 3632 25348
691 Congenital anomalies of skin dermatologic Both 0.3573 1.05 0.948,1.16 411 4110 0.3319 1.05 0.949,1.17 390 4020
694 Dyschromia and Vitiligo dermatologic Both 0.743 0.99 0.935,1.05 1286 12819 0.6324 0.941 0.734,1.21 66 657
694.1 Vitiligo dermatologic Both 0.778 0.97 0.786,1.2 94 931 0.6442 0.951 0.767,1.18 89 910
694.2 Other dyschromia dermatologic Both 0.8531 0.994 0.936,1.06 1146 11421 0.9268 0.997 0.938,1.06 1112 11050
694.3 Vascular disorders of skin dermatologic Both 0.4477 0.911 0.715,1.16 69 686 0.6324 0.941 0.734,1.21 66 657
695 Erythematous conditions dermatologic Both 0.3516 1.02 0.981,1.06 3180 24642 0.0263 1.11 1.01,1.22 475 4948
695.2 Bullous dermatoses dermatologic Both 0.1318 0.832 0.655,1.06 68 658 0.1413 0.834 0.655,1.06 67 636
695.3 Rosacea dermatologic Both 0.2466 1.03 0.978,1.09 1405 14019 0.1706 1.04 0.983,1.1 1354 13540
695.4 Lupus (localized and systemic) dermatologic Both 0.6516 1.02 0.935,1.11 556 5556 0.26 1.05 0.962,1.16 515 5144
695.41 Cutaneous lupus erythematosus dermatologic Both 0.1675 0.902 0.779,1.04 196 1955 0.1963 0.908 0.783,1.05 193 1898
695.42 Systemic lupus erythematosus dermatologic Both 0.2723 1.05 0.961,1.15 530 5287 0.26 1.05 0.962,1.16 515 5144
695.7 Prurigo and Lichen dermatologic Both 0.9661 1.0 0.908,1.11 429 4275 0.9661 0.998 0.903,1.1 412 4130
695.8 Other specified erythematous conditions dermatologic Both 0.5675 1.02 0.943,1.11 613 6111 0.7362 1.01 0.932,1.1 596 5928
695.9 Unspecified erythematous condition dermatologic Both 0.02291 1.11 1.01,1.22 513 5102 0.0263 1.11 1.01,1.22 475 4948
696 Psoriasis and related disorders dermatologic Both 0.3273 1.03 0.969,1.1 1080 10781 0.5272 1.05 0.912,1.2 222 2164
696.3 Pityriasis dermatologic Both 1.0 1.0 0.771,1.3 64 640 0.9954 0.999 0.767,1.3 62 630
696.4 Psoriasis dermatologic Both 0.2858 1.04 0.971,1.11 1014 10115 0.5272 1.05 0.912,1.2 222 2164
696.41 Psoriasis vulgaris dermatologic Both 0.2254 1.04 0.974,1.12 918 9161 0.241 1.04 0.972,1.12 886 8865
696.42 Psoriatic arthropathy dermatologic Both 0.6324 1.03 0.902,1.18 225 2250 0.5272 1.05 0.912,1.2 222 2164
697 Sarcoidosis dermatologic Both 0.4246 0.95 0.838,1.08 265 2650 0.3251 0.937 0.824,1.07 253 2559
698 Pruritus and related conditions dermatologic Both 0.9886 1.0 0.951,1.05 1686 16680 0.7063 0.99 0.941,1.04 1597 16185
700 Corns and callosities dermatologic Both 0.4797 0.973 0.903,1.05 764 7615 0.6839 0.984 0.912,1.06 731 7334
701 Other hypertrophic and atrophic conditions of skin dermatologic Both 0.3724 0.987 0.96,1.02 5838 31889 0.2972 1.06 0.947,1.19 313 3148
701.1 Keratoderma, acquired dermatologic Both 0.1496 0.927 0.837,1.03 389 3845 0.2239 0.936 0.842,1.04 361 3702
701.2 Scar conditions and fibrosis of skin dermatologic Both 0.4808 1.02 0.969,1.07 1705 16953 0.7047 1.01 0.96,1.06 1645 16434
701.3 Circumscribed scleroderma dermatologic Both 0.5728 1.03 0.932,1.14 434 4334 0.7194 1.02 0.92,1.13 408 4189
701.4 Keloid scar dermatologic Both 0.5117 0.968 0.877,1.07 454 4503 0.6138 0.975 0.883,1.08 441 4378
701.5 Abnormal granulation tissue dermatologic Both 0.3508 1.06 0.942,1.18 328 3260 0.2972 1.06 0.947,1.19 313 3148
702 Degenerative skin conditions and other dermatoses dermatologic Both 0.2328 0.982 0.953,1.01 5351 24908 0.5023 1.1 0.838,1.44 59 610
702.1 Actinic keratosis dermatologic Both 0.5741 0.989 0.953,1.03 3236 22206 0.7798 0.995 0.957,1.03 3073 21372
702.2 Seborrheic keratosis dermatologic Both 0.0912 0.972 0.94,1.0 4151 26248 0.1762 0.977 0.944,1.01 3967 25342
702.4 Degenerative skin disorders dermatologic Both 0.6699 1.06 0.815,1.37 63 624 0.5023 1.1 0.838,1.44 59 610
703 Diseases of nail, NOS dermatologic Both 0.5848 0.982 0.921,1.05 1033 10222 0.6223 0.978 0.897,1.07 556 5589
703.1 Ingrowing nail dermatologic Both 0.7079 0.984 0.903,1.07 580 5773 0.6223 0.978 0.897,1.07 556 5589
704 Diseases of hair and hair follicles dermatologic Both 0.7816 1.01 0.964,1.05 2321 22718 0.8511 1.01 0.948,1.07 1242 12390
704.1 Alopecia dermatologic Both 0.4764 0.977 0.918,1.04 1074 10601 0.5224 1.09 0.829,1.45 56 564
704.11 Alopecia Areata dermatologic Both 0.5152 1.1 0.833,1.44 58 580 0.5224 1.09 0.829,1.45 56 564
704.2 Hirsutism dermatologic Both 0.9661 0.997 0.869,1.14 227 2263 0.879 1.01 0.879,1.16 220 2216
704.8 Other specified diseases of hair and hair follicles dermatologic Both 0.8072 1.01 0.951,1.07 1286 12791 0.8511 1.01 0.948,1.07 1242 12390
705 Disorders of sweat glands dermatologic Both 0.7278 0.983 0.892,1.08 439 4376 0.2858 0.961 0.894,1.03 805 8140
705.1 Dyshidrosis dermatologic Both 0.4236 1.08 0.893,1.31 114 1131 0.3724 1.09 0.898,1.33 109 1089
705.3 Hidradenitis dermatologic Both 0.7244 0.973 0.838,1.13 183 1815 0.787 0.979 0.84,1.14 176 1776
705.8 Hyperhidrosis dermatologic Both 0.2065 0.955 0.89,1.03 846 8429 0.2858 0.961 0.894,1.03 805 8140
706 Diseases of sebaceous glands dermatologic Both 0.5495 0.99 0.96,1.02 4454 32859 0.471 1.02 0.961,1.09 1073 10711
706.1 Acne dermatologic Both 0.871 1.0 0.958,1.05 1931 17499 0.9183 1.0 0.956,1.05 1885 17070
706.2 Sebaceous cyst dermatologic Both 0.455 0.983 0.941,1.03 2150 21106 0.5082 0.985 0.942,1.03 2063 20422
706.8 Other specified diseases of sebaceous glands dermatologic Both 0.4842 1.02 0.961,1.09 1124 11122 0.471 1.02 0.961,1.09 1073 10711
707 Chronic ulcer of skin dermatologic Both 0.8166 0.995 0.952,1.04 2193 21811 0.787 1.01 0.952,1.07 1269 12947
707.1 Decubitus ulcer dermatologic Both 0.7396 0.986 0.907,1.07 600 5984 0.8128 0.99 0.908,1.08 565 5772
707.2 Chronic ulcer of leg or foot dermatologic Both 0.8054 0.99 0.917,1.07 721 7166 0.6745 0.983 0.909,1.06 685 6926
707.3 Chronic ulcer of unspecified site dermatologic Both 0.7228 1.01 0.955,1.07 1339 13370 0.787 1.01 0.952,1.07 1269 12947
709 Diffuse diseases of connective tissue dermatologic Both 0.1099 0.951 0.894,1.01 1086 10825 0.2812 0.956 0.882,1.04 641 6348
709.2 Sicca syndrome dermatologic Both 0.2559 0.941 0.846,1.05 365 3650 0.2877 0.943 0.847,1.05 352 3514
709.3 Systemic sclerosis dermatologic Both 0.26 0.918 0.792,1.07 184 1840 0.2965 0.923 0.793,1.07 177 1787
709.5 Dermatomyositis dermatologic Both 0.2723 1.15 0.897,1.47 70 700 0.1652 1.2 0.928,1.55 66 679
709.6 Other specified diffuse diseases of connective tissue dermatologic Both 0.695 0.954 0.755,1.21 78 780 0.9141 0.987 0.78,1.25 76 761
709.7 Unspecified diffuse connective tissue disease dermatologic Both 0.263 0.955 0.882,1.03 659 6563 0.2812 0.956 0.882,1.04 641 6348
939 Atopic/contact dermatitis due to other or unspecified dermatologic Both 0.7621 0.995 0.966,1.03 5120 27320 0.7852 1.04 0.802,1.34 64 599
939.1 Contact and allergic dermatitis of eyelid dermatologic Both 0.7211 1.05 0.812,1.35 64 626 0.7852 1.04 0.802,1.34 64 599
710 Osteomyelitis, periostitis, and other infections involving bone musculoskeletal Both 0.3589 0.969 0.907,1.04 954 9524 0.2716 0.961 0.895,1.03 832 8347
710.1 Osteomyelitis musculoskeletal Both 0.547 0.979 0.915,1.05 914 9127 0.2716 0.961 0.895,1.03 832 8347
710.11 Acute osteomyelitis musculoskeletal Both 0.309 0.95 0.86,1.05 425 4234 0.3119 0.949 0.857,1.05 407 4092
710.12 Chronic osteomyelitis musculoskeletal Both 0.6026 0.973 0.876,1.08 378 3758 0.7568 0.983 0.884,1.09 363 3620
710.19 Unspecified osteomyelitis musculoskeletal Both 0.4198 0.972 0.907,1.04 867 8656 0.2716 0.961 0.895,1.03 832 8347
711 Arthropathy associated with infections musculoskeletal Both 0.879 0.991 0.884,1.11 314 3124 0.5521 0.959 0.836,1.1 218 2127
711.1 Pyogenic arthritis musculoskeletal Both 0.4977 0.954 0.833,1.09 223 2206 0.5521 0.959 0.836,1.1 218 2127
712 Infective connective tissue disorders musculoskeletal Both 0.6138 1.05 0.877,1.25 136 1360 0.4188 1.08 0.897,1.3 124 1302
713 Arthropathy associated with other disorders classified elsewhere musculoskeletal Both 0.01995 0.854 0.748,0.976 222 2214 0.2864 0.903 0.749,1.09 113 1124
713.5 Arthropathy associated with neurological disorders musculoskeletal Both 0.1202 0.866 0.722,1.04 118 1180 0.2864 0.903 0.749,1.09 113 1124
714 Rheumatoid arthritis and other inflammatory polyarthropathies musculoskeletal Both 0.9183 0.997 0.948,1.05 1649 14662 0.7889 1.01 0.952,1.07 1297 11902
714.1 Rheumatoid arthritis musculoskeletal Both 0.9484 0.998 0.943,1.06 1342 12332 0.7889 1.01 0.952,1.07 1297 11902
715 Other inflammatory spondylopathies musculoskeletal Both 0.7621 0.99 0.928,1.06 979 9761 0.5808 0.957 0.819,1.12 175 1697
715.1 Sacroiliitis NEC musculoskeletal Both 0.9397 1.01 0.873,1.16 212 2120 0.8954 1.01 0.876,1.16 206 2054
715.2 Ankylosing spondylitis musculoskeletal Both 0.6622 0.966 0.827,1.13 177 1760 0.5808 0.957 0.819,1.12 175 1697
716 Other arthropathies musculoskeletal Both 0.3556 0.989 0.966,1.01 10893 26011 0.6668 0.995 0.972,1.02 10423 25263
716.1 Unspecified polyarthropathy or polyarthritis musculoskeletal Both 0.4667 0.941 0.799,1.11 155 1540 0.561 0.951 0.804,1.13 145 1479
716.2 Unspecified monoarthritis musculoskeletal Both 0.7745 1.03 0.853,1.24 116 1156 0.7311 1.03 0.857,1.25 115 1121
716.9 Arthropathy NOS musculoskeletal Both 0.4305 0.991 0.968,1.01 10831 26002 0.6668 0.995 0.972,1.02 10423 25263
717 Polymyalgia Rheumatica musculoskeletal Both 0.4519 0.948 0.825,1.09 210 2061 0.3373 0.933 0.809,1.08 200 1962
720 Spinal stenosis musculoskeletal Both 0.7015 1.01 0.971,1.04 3298 24117 0.9204 1.0 0.96,1.05 2338 19661
720.1 Spinal stenosis of lumbar region musculoskeletal Both 0.9572 1.0 0.96,1.04 2415 20454 0.9204 1.0 0.96,1.05 2338 19661
721 Spondylosis and allied disorders musculoskeletal Both 0.9141 1.0 0.97,1.03 4494 27007 0.2317 1.09 0.946,1.26 203 2027
721.1 Spondylosis without myelopathy musculoskeletal Both 0.984 1.0 0.968,1.03 4206 26584 0.9931 1.0 0.967,1.03 4056 25685
721.2 Spondylosis with myelopathy musculoskeletal Both 0.6397 0.982 0.91,1.06 740 7398 0.5821 0.978 0.906,1.06 726 7100
721.8 Other allied disorders of spine musculoskeletal Both 0.2307 1.09 0.947,1.25 212 2099 0.2317 1.09 0.946,1.26 203 2027
722 Intervertebral disc disorders musculoskeletal Both 0.9908 1.0 0.971,1.03 5242 28702 0.2655 0.97 0.92,1.02 1522 15140
722.1 Displacement of intervertebral disc musculoskeletal Both 0.4887 0.987 0.95,1.02 3038 26827 0.4355 0.985 0.948,1.02 2952 25946
722.3 Schmorl's nodes musculoskeletal Both 0.9772 0.997 0.822,1.21 115 1140 0.7396 0.967 0.793,1.18 111 1107
722.6 Degeneration of intervertebral disc musculoskeletal Both 0.4645 1.01 0.978,1.05 3338 26140 0.4266 1.02 0.978,1.05 3211 25241
722.7 Intervertebral disc disorder with myelopathy musculoskeletal Both 0.5058 1.03 0.939,1.14 464 4634 0.6622 1.02 0.928,1.13 452 4454
722.8 Postlaminectomy syndrome musculoskeletal Both 0.6501 0.974 0.871,1.09 336 3360 0.5546 0.966 0.863,1.08 326 3242
722.9 Other and unspecified disc disorder musculoskeletal Both 0.2944 0.973 0.923,1.02 1569 15676 0.2655 0.97 0.92,1.02 1522 15140
723 Other disorders of cervical region musculoskeletal Both 0.6998 1.01 0.942,1.09 761 7610 0.4436 1.06 0.91,1.24 182 1815
723.1 Torticollis musculoskeletal Both 0.3802 1.07 0.919,1.25 187 1870 0.4436 1.06 0.91,1.24 182 1815
724 Other and unspecified disorders of back musculoskeletal Both 0.7925 1.0 0.969,1.04 3338 26730 0.6966 1.01 0.954,1.07 1211 11955
724.1 Disorders of sacrum musculoskeletal Both 0.798 1.01 0.959,1.06 1804 17663 0.9057 1.0 0.955,1.05 1755 17091
724.2 Disorders of coccyx musculoskeletal Both 0.6592 1.03 0.916,1.15 331 3290 0.8472 1.01 0.901,1.14 317 3183
724.8 Other symptoms referable to back musculoskeletal Both 0.302 0.961 0.892,1.04 753 7499 0.2844 0.959 0.889,1.04 726 7259
724.9 Other unspecified back disorders musculoskeletal Both 0.6516 1.01 0.956,1.07 1246 12418 0.6966 1.01 0.954,1.07 1211 11955
726 Peripheral enthesopathies and allied syndromes musculoskeletal Both 0.5152 1.01 0.983,1.03 7682 25455 0.9141 1.0 0.936,1.08 859 8543
726.1 Enthesopathy musculoskeletal Both 0.2972 1.02 0.987,1.05 5795 25454 0.2339 1.02 0.989,1.05 5619 24691
726.2 Synoviopathy musculoskeletal Both 0.9863 0.999 0.927,1.08 774 7723 0.9036 1.0 0.932,1.08 755 7434
726.3 Bursitis musculoskeletal Both 0.2296 1.04 0.978,1.1 1339 13090 0.2339 1.04 0.978,1.1 1294 12641
726.4 Calcaneal spur; Exostosis NOS musculoskeletal Both 0.975 1.0 0.935,1.07 889 8846 0.9141 1.0 0.936,1.08 859 8543
727 Other disorders of synovium, tendon, and bursa musculoskeletal Both 0.7328 0.995 0.967,1.02 5811 25457 0.5649 1.06 0.875,1.28 114 1103
727.1 Synovitis and tenosynovitis musculoskeletal Both 0.4898 1.02 0.973,1.06 2342 20541 0.3112 1.02 0.979,1.07 2279 19923
727.2 Bursitis disorders musculoskeletal Both 0.2168 0.932 0.834,1.04 341 3381 0.2958 0.942 0.841,1.05 332 3258
727.4 Ganglion and cyst of synovium, tendon, and bursa musculoskeletal Both 0.04266 0.938 0.882,0.998 1109 11034 0.03802 0.936 0.879,0.996 1073 10667
727.5 Rupture of synovium musculoskeletal Both 0.309 1.06 0.95,1.17 376 3718 0.2109 1.07 0.962,1.19 361 3571
727.6 Rupture of tendon, nontraumatic musculoskeletal Both 0.526 0.985 0.94,1.03 1927 18092 0.5916 0.987 0.941,1.04 1880 17429
727.7 Contracture of tendon (sheath) musculoskeletal Both 0.2911 0.953 0.871,1.04 520 5187 0.3112 0.954 0.872,1.04 509 5041
727.8 Plica syndrome musculoskeletal Both 0.6353 1.05 0.867,1.26 115 1117 0.5649 1.06 0.875,1.28 114 1103
728 Disorders of muscle, ligament, and fascia musculoskeletal Both 0.7031 0.993 0.958,1.03 3433 24951 0.8933 0.992 0.882,1.12 298 2980
728.1 Muscular calcification and ossification musculoskeletal Both 0.6368 0.946 0.749,1.19 69 682 0.7345 0.96 0.759,1.21 68 658
728.2 Laxity of ligament or hypermobility syndrome musculoskeletal Both 0.7852 1.02 0.894,1.16 230 2298 0.8054 1.02 0.891,1.16 224 2230
728.7 Fasciitis musculoskeletal Both 0.879 0.996 0.952,1.04 2056 19042 0.8933 0.992 0.882,1.12 298 2980
728.71 Contracture of palmar fascia [Dupuytren's disease] musculoskeletal Both 0.8299 0.987 0.879,1.11 310 3095 0.8933 0.992 0.882,1.12 298 2980
729 Other disorders of soft tissues musculoskeletal Both 0.03467 1.04 1.0,1.09 2618 22751 0.1012 1.27 0.954,1.69 51 513
729.1 Rheumatism, unspecified and fibrositis musculoskeletal Both 0.8414 1.03 0.797,1.32 63 630 1.0 1.0 0.776,1.29 62 611
729.3 Panniculitis musculoskeletal Both 0.08913 0.834 0.677,1.03 100 1000 0.1135 0.843 0.682,1.04 97 972
729.7 Nontraumatic compartment syndrome musculoskeletal Both 0.08128 1.29 0.969,1.71 53 530 0.1012 1.27 0.954,1.69 51 513
731 Osteitis deformans and osteopathies associated with other disorders classified elsewhere musculoskeletal Both 0.6998 0.968 0.819,1.14 145 1441 0.859 0.984 0.828,1.17 136 1388
732 Osteochondropathies musculoskeletal Both 0.8395 1.01 0.895,1.15 289 2882 0.1824 1.18 0.924,1.51 70 693
732.1 Juvenile osteochondrosis musculoskeletal Both 0.5408 1.05 0.891,1.25 157 1570 0.4853 1.06 0.896,1.26 153 1520
732.7 Osteochondritis dissecans musculoskeletal Both 0.2366 1.16 0.908,1.48 71 710 0.1824 1.18 0.924,1.51 70 693
733 Other disorders of bone and cartilage musculoskeletal Both 0.04074 0.963 0.929,0.998 3481 21966 0.8395 0.977 0.781,1.22 78 783
733.2 Cyst of bone musculoskeletal Both 0.865 1.01 0.865,1.19 162 1613 0.9419 1.01 0.856,1.18 154 1562
733.4 Aseptic necrosis of bone musculoskeletal Both 0.02754 0.89 0.803,0.987 405 4042 0.01023 0.872 0.785,0.968 393 3900
733.6 Costochondritis musculoskeletal Both 0.9484 0.996 0.88,1.13 275 2742 0.743 0.979 0.864,1.11 268 2671
733.8 Malunion and nonunion of fracture musculoskeletal Both 0.5383 0.976 0.904,1.05 701 7003 0.52 0.975 0.902,1.05 694 6780
733.9 Chondromalacia musculoskeletal Both 0.6776 0.954 0.763,1.19 80 800 0.8395 0.977 0.781,1.22 78 783
735 Acquired foot deformities musculoskeletal Both 0.7621 1.01 0.965,1.05 2431 23304 0.6668 0.986 0.924,1.05 1012 9954
735.1 Flat foot musculoskeletal Both 0.6223 1.03 0.929,1.13 437 4355 0.526 1.03 0.934,1.14 418 4202
735.2 Acquired toe deformities musculoskeletal Both 0.5794 1.02 0.951,1.09 869 8616 0.07079 1.12 0.991,1.26 291 2860
735.21 Hammer toe (acquired) musculoskeletal Both 0.5675 1.03 0.938,1.12 509 5041 0.3837 1.04 0.951,1.14 498 4838
735.23 Hallux rigidus musculoskeletal Both 0.07586 1.11 0.989,1.26 299 2975 0.07079 1.12 0.991,1.26 291 2860
735.3 Hallux valgus (Bunion) musculoskeletal Both 0.5546 0.981 0.921,1.05 1039 10308 0.6668 0.986 0.924,1.05 1012 9954
736 Other acquired deformities of limbs musculoskeletal Both 0.4416 0.982 0.938,1.03 1997 19771 0.4169 0.948 0.832,1.08 250 2469
736.1 Acquired deformities of forearm musculoskeletal Both 0.6561 1.05 0.846,1.3 90 892 0.6194 1.06 0.851,1.31 90 860
736.2 Acquired deformities of finger musculoskeletal Both 0.5164 1.05 0.9,1.23 169 1684 0.4436 1.06 0.908,1.25 168 1625
736.4 Genu valgum or varum (acquired) musculoskeletal Both 0.4688 0.952 0.833,1.09 239 2382 0.5781 0.962 0.84,1.1 232 2297
736.5 Acquired deformities of knee musculoskeletal Both 0.7852 1.02 0.878,1.19 184 1834 0.7516 1.02 0.88,1.19 179 1779
736.6 Unequal leg length (acquired) musculoskeletal Both 0.3396 0.939 0.827,1.07 256 2555 0.4169 0.948 0.832,1.08 250 2469
737 Curvature of spine musculoskeletal Both 0.7656 1.01 0.952,1.07 1268 12573 0.6714 1.01 0.95,1.08 966 9478
737.1 Kyphosis (acquired) musculoskeletal Both 0.4046 0.956 0.861,1.06 383 3819 0.4436 0.96 0.863,1.07 376 3661
737.2 Lordosis (acquired) musculoskeletal Both 0.2366 1.15 0.912,1.45 65 650 0.2128 1.16 0.918,1.47 64 630
737.3 Kyphoscoliosis and scoliosis musculoskeletal Both 0.7586 1.01 0.946,1.08 987 9782 0.6714 1.01 0.95,1.08 966 9478
738 Other acquired musculoskeletal deformity musculoskeletal Both 0.3097 1.02 0.978,1.07 1968 19555 0.9057 1.0 0.936,1.08 841 8262
738.4 Acquired spondylolisthesis musculoskeletal Both 0.8414 1.01 0.939,1.08 863 8617 0.9057 1.0 0.936,1.08 841 8262
739 Contracture of joint musculoskeletal Both 0.3334 1.05 0.956,1.14 522 5203 0.3133 1.05 0.957,1.15 510 5033
740 Osteoarthrosis musculoskeletal Both 0.4487 0.991 0.97,1.01 13133 25195 0.5916 0.994 0.971,1.02 12155 24385
740.1 Osteoarthritis; localized musculoskeletal Both 0.9572 0.999 0.969,1.03 5329 22764 0.3864 0.96 0.876,1.05 497 4971
740.11 Osteoarthrosis, localized, primary musculoskeletal Both 0.9661 1.0 0.969,1.03 4543 21500 0.9795 1.0 0.967,1.03 4380 20835
740.12 Osteoarthrosis, localized, secondary musculoskeletal Both 0.4365 0.965 0.881,1.06 514 5125 0.3864 0.96 0.876,1.05 497 4971
740.2 Osteoarthrosis, generalized musculoskeletal Both 0.8035 1.01 0.95,1.07 1266 9917 0.7603 1.01 0.95,1.07 1221 9541
740.3 Osteoarthrosis involving more than one site, but not specified as generalized musculoskeletal Both 0.6266 1.03 0.914,1.16 303 2974 0.514 1.04 0.923,1.17 296 2850
740.9 Osteoarthrosis NOS musculoskeletal Both 0.4539 0.991 0.969,1.01 12648 25075 0.5916 0.994 0.971,1.02 12155 24385
741 Symptoms and disorders of the joints musculoskeletal Both 0.542 0.992 0.966,1.02 6764 29838 0.3112 1.16 0.868,1.56 52 512
741.1 Ankylosis of joint musculoskeletal Both 0.9441 0.995 0.863,1.15 209 2088 0.9977 1.0 0.867,1.15 207 2026
741.2 Stiffness of joint musculoskeletal Both 0.4688 0.976 0.914,1.04 995 9908 0.4775 0.976 0.914,1.04 966 9571
741.3 Difficulty in walking musculoskeletal Both 0.8222 0.995 0.948,1.04 1854 17778 0.743 0.992 0.945,1.04 1781 17109
741.4 Joint effusions musculoskeletal Both 0.4198 1.02 0.973,1.07 1930 19185 0.3112 1.02 0.977,1.07 1857 18574
741.5 Hemarthrosis musculoskeletal Both 0.5333 0.922 0.715,1.19 64 640 0.881 0.98 0.756,1.27 61 611
741.6 Villonodular synovitis musculoskeletal Both 0.2754 1.17 0.88,1.57 53 522 0.3112 1.16 0.868,1.56 52 512
742 Derangement of joint, non-traumatic musculoskeletal Both 0.8453 1.0 0.969,1.04 3462 27650 0.7145 0.993 0.957,1.03 3124 26067
742.1 Loose body in joint musculoskeletal Both 0.01202 1.26 1.05,1.5 131 1295 0.007586 1.27 1.07,1.52 130 1268
742.2 Pathological, developmental or recurrent dislocation musculoskeletal Both 0.4819 0.953 0.833,1.09 243 2414 0.5559 0.96 0.839,1.1 241 2373
742.8 Articular cartilage disorder musculoskeletal Both 0.7063 0.972 0.84,1.12 191 1896 0.8492 0.986 0.851,1.14 188 1854
742.9 Other derangement of joint musculoskeletal Both 0.7852 0.995 0.959,1.03 3212 26883 0.7145 0.993 0.957,1.03 3124 26067
743 Osteoporosis, osteopenia and pathological fracture musculoskeletal Both 0.3999 0.989 0.963,1.02 7571 30458 0.227 0.982 0.954,1.01 5560 28578
743.1 Osteoporosis musculoskeletal Both 0.5093 0.986 0.947,1.03 2982 15823 0.861 0.988 0.86,1.13 218 2202
743.11 Osteoporosis NOS musculoskeletal Both 0.3048 0.979 0.94,1.02 2931 15630 0.3206 0.979 0.939,1.02 2793 15093
743.12 Senile osteoporosis musculoskeletal Both 1.0 1.0 0.909,1.1 481 4333 0.9705 0.998 0.906,1.1 463 4168
743.13 Other specified osteoporosis musculoskeletal Both 0.9016 0.992 0.867,1.13 231 2290 0.861 0.988 0.86,1.13 218 2202
743.2 Pathologic fracture musculoskeletal Both 0.6761 0.985 0.919,1.06 872 8504 0.3532 0.909 0.744,1.11 108 1104
743.21 Pathologic fracture of vertebrae musculoskeletal Both 0.9333 1.0 0.904,1.12 385 3799 0.9162 0.994 0.892,1.11 362 3656
743.22 Pathologic fracture of femur musculoskeletal Both 0.2234 0.887 0.731,1.08 116 1143 0.3532 0.909 0.744,1.11 108 1104
743.4 Stress fracture musculoskeletal Both 0.8974 0.992 0.881,1.12 291 2882 0.8072 0.985 0.872,1.11 280 2800
743.9 Osteopenia or other disorder of bone and cartilage musculoskeletal Both 0.1807 0.98 0.953,1.01 5795 29464 0.227 0.982 0.954,1.01 5560 28578
745 Pain in joint musculoskeletal Both 0.7015 1.0 0.984,1.02 15755 22596 0.5272 1.01 0.986,1.03 15264 21891
747 Cardiac and circulatory congenital anomalies congenital anomalies Both 0.7691 1.01 0.96,1.06 1811 18049 0.4227 0.958 0.864,1.06 390 3882
747.1 Cardiac congenital anomalies congenital anomalies Both 0.7925 1.01 0.954,1.06 1446 14417 0.4875 0.962 0.861,1.07 333 3277
747.11 Cardiac shunt/ heart septal defect congenital anomalies Both 0.3908 1.04 0.951,1.14 519 5181 0.2864 1.05 0.96,1.15 507 5011
747.12 Valvular heart disease/ heart chambers congenital anomalies Both 0.975 0.999 0.92,1.08 632 6299 0.8414 1.01 0.928,1.1 616 6067
747.13 Congenital anomalies of great vessels congenital anomalies Both 0.4498 0.959 0.86,1.07 342 3387 0.4875 0.962 0.861,1.07 333 3277
747.2 Congenital anomalies of peripheral vascular system congenital anomalies Both 0.4335 0.96 0.867,1.06 402 4014 0.4227 0.958 0.864,1.06 390 3882
748 Anomalies of respiratory system, congenital congenital anomalies Both 0.8299 0.977 0.789,1.21 93 930 0.7962 0.972 0.784,1.21 91 896
749 Congenital anomalies of face and neck congenital anomalies Both 0.6427 0.977 0.886,1.08 455 4540 0.5383 0.934 0.75,1.16 88 873
749.1 Cleft palate congenital anomalies Both 0.618 0.942 0.746,1.19 81 791 0.6012 0.94 0.745,1.19 81 777
749.2 Congenital anomalies of skull and face bones congenital anomalies Both 0.5929 0.943 0.759,1.17 90 897 0.5383 0.934 0.75,1.16 88 873
750 Digestive congenital anomalies congenital anomalies Both 0.4603 0.972 0.901,1.05 739 7382 0.07943 0.865 0.735,1.02 167 1733
750.1 Upper gastrointestinal congenital anomalies congenital anomalies Both 0.8551 1.01 0.902,1.13 307 3069 0.1803 0.831 0.633,1.09 54 539
750.11 Esophageal atresia/tracheoesophageal fistula congenital anomalies Both 0.5333 1.07 0.869,1.31 96 944 0.4592 1.08 0.879,1.33 94 918
750.13 Congenital anomalies of mouth/tongue congenital anomalies Both 0.05754 1.24 0.993,1.54 77 767 0.05129 1.25 0.998,1.55 77 750
750.14 Congenital anomalies of esophagus congenital anomalies Both 0.3013 0.909 0.759,1.09 121 1210 0.507 0.94 0.784,1.13 118 1151
750.15 Congenital anomalies of stomach congenital anomalies Both 0.3776 0.887 0.681,1.16 57 567 0.1803 0.831 0.633,1.09 54 539
750.2 Lower gastrointestinal congenital anomalies congenital anomalies Both 0.4864 0.966 0.875,1.07 438 4363 0.07943 0.865 0.735,1.02 167 1733
750.21 Congenital anomalies of intestine congenital anomalies Both 0.5445 1.04 0.915,1.18 262 2613 0.5272 1.04 0.914,1.19 244 2548
750.22 Congenital anomaly of gallbladder, bile ducts, liver, pancreas congenital anomalies Both 0.05623 0.858 0.734,1.0 180 1790 0.07943 0.865 0.735,1.02 167 1733
751 Genitourinary congenital anomalies congenital anomalies Both 0.1683 0.965 0.918,1.01 1682 16764 0.873 0.987 0.84,1.16 154 1526
751.1 Congenital anomalies of genital organs congenital anomalies Both 0.7194 0.983 0.897,1.08 491 4897 0.4111 1.08 0.899,1.3 129 1266
751.11 Congenital anomalies of female genital organs congenital anomalies Female 0.6138 0.971 0.866,1.09 328 3280 0.4315 0.954 0.849,1.07 315 3206
751.12 Congenital anomalies of male genital organs congenital anomalies Male 0.455 1.07 0.894,1.28 132 1301 0.4111 1.08 0.899,1.3 129 1266
751.2 Congenital anomalies of urinary system congenital anomalies Both 0.3819 0.973 0.916,1.03 1139 11355 0.7586 0.98 0.86,1.12 240 2421
751.21 Cystic kidney disease congenital anomalies Both 0.4898 0.975 0.907,1.05 799 7929 0.5702 0.979 0.91,1.05 775 7663
751.22 Other specified congenital anomalies of kidney congenital anomalies Both 0.6592 0.972 0.855,1.1 251 2506 0.7586 0.98 0.86,1.12 240 2421
751.3 Obstructive genitourinary defect congenital anomalies Both 0.7551 0.975 0.83,1.14 157 1560 0.873 0.987 0.84,1.16 154 1526
752 Nervous system congenital anomalies congenital anomalies Both 0.6501 1.02 0.949,1.09 908 9073 0.415 1.06 0.918,1.23 195 1963
752.1 Neural tube defects congenital anomalies Both 0.4831 1.03 0.952,1.11 728 7277 0.1581 1.13 0.954,1.34 139 1411
752.11 Spina bifida congenital anomalies Both 0.2198 1.11 0.94,1.31 144 1440 0.1581 1.13 0.954,1.34 139 1411
752.2 Other specified congenital anomalies of nervous system congenital anomalies Both 0.4276 1.06 0.918,1.22 201 2010 0.415 1.06 0.918,1.23 195 1963
753 Congenital anomalies of the eye congenital anomalies Both 0.9376 1.01 0.853,1.19 146 1451 0.8395 1.02 0.859,1.21 139 1394
754 Congenital musculoskeletal deformities of spine congenital anomalies Both 0.7228 1.01 0.949,1.08 1006 10049 0.6934 1.02 0.927,1.12 456 4482
754.1 Lumbosacral spondylolysis, congenital congenital anomalies Both 0.8147 0.978 0.809,1.18 116 1155 0.8511 0.982 0.811,1.19 112 1125
754.2 Spondylolisthesis, congenital congenital anomalies Both 0.6324 1.02 0.932,1.12 470 4675 0.6934 1.02 0.927,1.12 456 4482
755 Congenital anomalies of limbs congenital anomalies Both 0.6577 0.982 0.904,1.07 625 6237 0.05888 0.851 0.72,1.01 151 1482
755.1 Congenital deformities of feet congenital anomalies Both 0.6152 1.03 0.918,1.16 315 3138 0.4677 1.04 0.929,1.17 311 3026
755.4 Congenital anomalies of upper limb, including shoulder girdle congenital anomalies Both 0.456 0.904 0.693,1.18 58 567 0.5333 0.918 0.701,1.2 57 551
755.6 Other congenital anomalies of lower limb, including pelvic girdle congenital anomalies Both 0.2028 0.919 0.808,1.05 258 2580 0.05888 0.851 0.72,1.01 151 1482
755.61 Congenital hip dysplasia and deformity congenital anomalies Both 0.05495 0.849 0.719,1.0 152 1520 0.05888 0.851 0.72,1.01 151 1482
756 Other congenital musculoskeletal anomalies congenital anomalies Both 0.6516 0.985 0.924,1.05 1021 10203 0.2218 0.954 0.885,1.03 723 7168
756.1 Congenital anomalies of abdominal wall; diaphram congenital anomalies Both 0.09333 1.25 0.963,1.62 55 527 0.13 1.23 0.942,1.6 52 512
756.2 Pectus and other congenital anomalies of ribs/sternum congenital anomalies Both 0.5495 1.09 0.827,1.43 56 524 0.4121 1.12 0.852,1.48 55 514
756.3 Congenital anomalies of muscle, tendon, fascia, and connective tissue congenital anomalies Both 0.5957 0.965 0.846,1.1 246 2459 0.5188 0.957 0.837,1.09 240 2394
756.5 Congenital osteodystrophies congenital anomalies Both 0.3141 0.962 0.893,1.04 743 7419 0.2218 0.954 0.885,1.03 723 7168
757 Congenital anomalies of the integument congenital anomalies Both 0.3776 0.947 0.839,1.07 283 2820 0.4477 0.953 0.842,1.08 267 2738
758 Chromosomal anomalies and genetic disorders congenital anomalies Both 0.2891 0.907 0.758,1.09 134 1334 0.8511 0.979 0.785,1.22 89 891
758.1 Chromosomal anomalies congenital anomalies Both 0.8851 0.984 0.791,1.22 91 910 0.8511 0.979 0.785,1.22 89 891
759 Other and unspecified congenital anomalies congenital anomalies Both 0.9226 0.995 0.908,1.09 498 4964 0.3972 0.886 0.67,1.17 55 548
759.1 Anomalies of endocrine glands, congenital congenital anomalies Both 0.6266 0.934 0.711,1.23 57 567 0.3972 0.886 0.67,1.17 55 548
760 Back pain symptoms Both 0.4365 0.992 0.971,1.01 12687 25663 0.3251 0.989 0.968,1.01 12273 24881
761 Cervicalgia symptoms Both 0.2773 1.02 0.987,1.05 5134 32829 0.2944 1.02 0.986,1.05 4982 31788
763 Thoracic or lumbosacral neuritis or radiculitis, unspecified symptoms Both 0.6266 1.01 0.972,1.05 2927 27356 0.7379 1.01 0.968,1.05 2837 26425
764 Sciatica symptoms Both 0.08128 0.965 0.927,1.0 2623 25291 0.07079 0.963 0.924,1.0 2527 24415
765 Cervical radiculitis symptoms Both 0.5012 0.981 0.929,1.04 1401 13966 0.4634 0.98 0.927,1.04 1359 13502
766 Neuralgia, neuritis, and radiculitis NOS symptoms Both 0.7586 1.01 0.973,1.04 4004 31031 0.8035 1.0 0.971,1.04 3874 30042
767 Cervicocranial/Cervicobrachial syndrome symptoms Both 0.1059 1.19 0.964,1.47 85 835 0.06761 1.22 0.985,1.51 83 808
769 Nonallopathic lesions NEC symptoms Both 0.7194 0.988 0.924,1.06 923 9183 0.8492 0.993 0.928,1.06 901 8876
770 Myalgia and myositis unspecified symptoms Both 0.3524 0.985 0.953,1.02 4324 27592 0.4335 0.987 0.955,1.02 4180 26740
771 Musculoskeletal symptoms referable to limbs symptoms Both 0.9616 1.0 0.967,1.04 3638 29710 0.6353 0.982 0.911,1.06 749 7601
771.1 Swelling of limb symptoms Both 0.5082 1.01 0.979,1.04 4511 29862 0.3631 1.02 0.983,1.05 4278 28990
771.2 Cramp of limb symptoms Both 0.6067 0.981 0.912,1.06 791 7856 0.6353 0.982 0.911,1.06 749 7601
772 Symptoms of the muscles symptoms Both 0.8551 0.995 0.945,1.05 1549 15345 0.5248 1.04 0.929,1.15 368 3615
772.1 Muscular wasting and disuse atrophy symptoms Both 0.861 1.01 0.902,1.13 320 3187 0.7499 1.02 0.909,1.14 316 3091
772.2 Spasm of muscle symptoms Both 0.3266 0.976 0.93,1.02 1780 17782 0.3112 0.975 0.928,1.02 1722 17241
772.3 Muscle weakness symptoms Both 0.8017 0.995 0.953,1.04 2339 22770 0.9204 1.0 0.96,1.05 2260 21976
772.4 Rhabdomyolysis symptoms Both 0.1614 1.15 0.947,1.39 117 1170 0.1514 1.15 0.949,1.4 114 1134
772.6 Facial weakness symptoms Both 0.7691 1.02 0.913,1.13 377 3746 0.5248 1.04 0.929,1.15 368 3615
773 Pain in limb symptoms Both 0.2547 1.01 0.991,1.04 11393 26958 0.2046 1.01 0.992,1.04 11005 26150
780 Hypothermia/Chills symptoms Both 0.2931 1.06 0.948,1.2 307 3069 0.2799 1.07 0.948,1.2 284 2965
781 Symptoms involving nervous and musculoskeletal systems symptoms Both 0.5093 0.984 0.937,1.03 1767 17206 0.5333 0.935 0.755,1.16 90 857
781.1 Loss of height symptoms Both 0.4519 0.922 0.745,1.14 91 890 0.5333 0.935 0.755,1.16 90 857
782.3 Edema symptoms Both 0.4188 1.01 0.982,1.05 4591 30849 0.3784 1.01 0.983,1.05 4356 29916
782.6 Pallor and flushing symptoms Both 0.1888 0.948 0.875,1.03 679 6769 0.2698 0.955 0.881,1.04 655 6586
783 Fever of unknown origin symptoms Both 0.2742 0.983 0.953,1.01 4616 33703 0.4977 0.954 0.832,1.09 227 2410
783.1 Postprocedural fever symptoms Both 0.4932 0.955 0.838,1.09 248 2473 0.4977 0.954 0.832,1.09 227 2410
785 Abdominal pain symptoms Both 0.5875 0.994 0.973,1.02 13257 25098 0.4198 0.991 0.97,1.01 12542 24617
788 Syncope and collapse symptoms Both 0.9705 0.999 0.962,1.04 3017 29114 0.8892 1.0 0.965,1.04 2889 28175
789 Nausea and vomiting symptoms Both 0.5902 0.993 0.969,1.02 8497 29838 0.2158 0.948 0.87,1.03 590 6182
789.1 Persistent vomiting symptoms Both 0.2891 0.956 0.881,1.04 634 6330 0.2158 0.948 0.87,1.03 590 6182
790 Nonspecific findings on examination of blood symptoms Both 0.309 0.975 0.927,1.02 1740 17356 0.02455 0.801 0.66,0.972 120 1188
790.1 Elevated sedimentation rate symptoms Both 0.859 0.986 0.839,1.16 158 1580 0.7656 1.03 0.869,1.21 150 1538
790.6 Other abnormal blood chemistry symptoms Both 0.3428 1.01 0.984,1.05 4849 31554 0.3119 1.02 0.985,1.05 4602 30638
790.8 Elevated C-reactive protein (CRP) symptoms Both 0.7261 0.975 0.847,1.12 204 2026 0.9099 1.01 0.873,1.16 198 1970
790.9 Abnormal arterial blood gases symptoms Both 0.0309 0.81 0.669,0.981 123 1230 0.02455 0.801 0.66,0.972 120 1188
791 Gangrene symptoms Both 0.3141 1.08 0.933,1.24 212 2104 0.3459 1.07 0.927,1.24 197 2012
792 Abnormal Papanicolaou smear of cervix and cervical HPV symptoms Female 0.3926 1.02 0.974,1.07 2171 11972 0.871 1.01 0.935,1.08 796 7682
792.1 Papanicolaou smear of cervix or vagina with atypical squamous cells symptoms Female 0.9354 1.0 0.933,1.08 841 7806 0.871 1.01 0.935,1.08 796 7682
793 Nonspecific abnormal findings on radiological and other examination of musculoskeletal system symptoms Both 0.3784 0.963 0.885,1.05 588 5848 0.004786 0.929 0.882,0.978 1584 16032
793.2 Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc) symptoms Both 0.005012 0.931 0.885,0.979 1661 16601 0.004786 0.929 0.882,0.978 1584 16032
794 Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc) symptoms Both 0.7943 1.01 0.919,1.12 433 4330 0.9506 0.997 0.901,1.1 409 4188
795 Other and nonspecific abnormal cytological, histological and immunological findings symptoms Both 0.879 1.0 0.954,1.06 1632 15619 0.5521 0.952 0.809,1.12 153 1606
795.8 Abnormal tumor markers symptoms Both 0.3404 0.976 0.927,1.03 1698 13664 0.5521 0.952 0.809,1.12 153 1606
795.82 Elevated cancer antigen 125 [CA 125] symptoms Both 0.7638 0.976 0.836,1.14 167 1662 0.5521 0.952 0.809,1.12 153 1606
796 Elevated prostate specific antigen [PSA] symptoms Male 0.8072 0.993 0.941,1.05 1700 8294 0.7178 0.99 0.937,1.05 1641 7985
797 Shock symptoms Both 0.171 1.07 0.971,1.18 445 4446 0.07244 1.15 0.987,1.35 178 1754
797.1 Cardiogenic shock symptoms Both 0.07586 1.15 0.986,1.34 183 1822 0.07244 1.15 0.987,1.35 178 1754
798 Malaise and fatigue symptoms Both 0.208 1.02 0.991,1.04 8867 29476 0.1849 0.962 0.908,1.02 1281 12996
798.1 Chronic fatigue syndrome symptoms Both 0.1524 0.96 0.907,1.02 1349 13380 0.1849 0.962 0.908,1.02 1281 12996
799 Debility unspecified symptoms Both 0.6902 1.01 0.961,1.06 1672 16007 0.4446 1.02 0.969,1.07 1568 15408
800 Fracture of lower limb injuries & poisonings Both 0.415 0.98 0.935,1.03 1879 18684 0.004074 0.841 0.747,0.946 285 2809
800.1 Fracture of neck of femur injuries & poisonings Both 0.7943 0.987 0.892,1.09 409 4028 0.9594 0.997 0.9,1.11 393 3871
800.2 Fracture of unspecified part of femur injuries & poisonings Both 0.8072 1.01 0.926,1.1 539 5364 0.7482 1.01 0.928,1.11 518 5177
800.3 Fracture of tibia and fibula injuries & poisonings Both 0.7464 0.988 0.916,1.06 744 7420 0.8995 1.0 0.931,1.08 719 7192
800.4 Fracture of patella injuries & poisonings Both 0.002399 0.835 0.743,0.938 293 2904 0.004074 0.841 0.747,0.946 285 2809
801 Fracture of ankle and foot injuries & poisonings Both 0.8872 1.0 0.956,1.05 1804 17960 0.9705 0.999 0.932,1.07 887 8823
801.1 Fracture of foot injuries & poisonings Both 0.6501 0.984 0.919,1.05 913 9098 0.9705 0.999 0.932,1.07 887 8823
802 Fracture of pelvis injuries & poisonings Both 0.1507 0.921 0.823,1.03 321 3192 0.1807 0.925 0.825,1.04 308 3088
803 Fracture of upper limb injuries & poisonings Both 0.9311 1.0 0.953,1.05 1644 16288 0.9016 0.994 0.897,1.1 405 4053
803.1 Fracture of humerus injuries & poisonings Both 0.302 0.956 0.878,1.04 592 5913 0.3715 0.961 0.881,1.05 571 5724
803.2 Fracture of radius and ulna injuries & poisonings Both 0.9333 1.0 0.937,1.07 899 8929 0.6918 0.974 0.856,1.11 237 2385
803.21 Colles' fracture injuries & poisonings Both 0.6982 0.975 0.859,1.11 248 2475 0.6918 0.974 0.856,1.11 237 2385
803.3 Fracture of clavicle or scapula injuries & poisonings Both 0.929 0.995 0.9,1.1 419 4190 0.9016 0.994 0.897,1.1 405 4053
804 Fracture of hand or wrist injuries & poisonings Both 0.7228 0.99 0.934,1.05 1272 12504 0.8453 0.994 0.938,1.05 1245 12127
805 Fracture of vertebral column without mention of spinal cord injury injuries & poisonings Both 0.6053 0.984 0.924,1.05 1082 10755 0.5117 0.979 0.918,1.04 1035 10370
807 Fracture of ribs injuries & poisonings Both 0.3581 1.04 0.954,1.14 543 5428 0.4764 1.03 0.944,1.13 515 5225
809 Fracture of unspecified bones injuries & poisonings Both 0.7674 1.01 0.965,1.05 2426 23282 0.7907 1.01 0.964,1.05 2358 22537
817 Concussion injuries & poisonings Both 0.0389 1.08 1.0,1.17 771 7696 0.03467 1.08 1.01,1.17 754 7503
818 Intracranial hemorrhage (injury) injuries & poisonings Both 0.4335 1.05 0.925,1.2 240 2380 0.1905 1.15 0.931,1.43 82 814
818.1 Subdural hemorrhage (injury) injuries & poisonings Both 0.8035 1.03 0.817,1.3 74 740 0.5408 1.08 0.85,1.36 71 716
818.2 Subarachnoid hemorrhage (injury) injuries & poisonings Both 0.2404 1.14 0.918,1.41 84 837 0.1905 1.15 0.931,1.43 82 814
819 Skull and face fracture and other intercranial injury injuries & poisonings Both 0.173 1.03 0.985,1.09 1782 17605 0.1288 1.04 0.989,1.09 1741 17082
830 Dislocation injuries & poisonings Both 0.3784 1.02 0.98,1.05 3129 28682 0.3251 1.02 0.982,1.06 3060 27775
835 Internal derangement of knee injuries & poisonings Both 0.9462 1.0 0.954,1.05 1774 17453 0.9162 1.0 0.954,1.05 1729 16925
836 Traumatic arthropathy injuries & poisonings Both 0.3381 0.952 0.861,1.05 423 4213 0.3491 0.953 0.861,1.05 412 4079
840 Sprains and strains injuries & poisonings Both 0.4603 1.01 0.983,1.04 6106 31582 0.5248 0.986 0.943,1.03 2221 18991
840.1 Muscle/tendon sprain injuries & poisonings Both 0.7998 0.987 0.894,1.09 429 4269 0.8241 0.989 0.894,1.09 408 4111
840.2 Rotator cuff (capsule) sprain injuries & poisonings Both 0.6998 0.989 0.935,1.05 1343 13394 0.869 0.995 0.941,1.05 1311 12884
840.3 Joint/ligament sprain injuries & poisonings Both 0.4721 0.984 0.942,1.03 2261 19530 0.5248 0.986 0.943,1.03 2221 18991
841 Sprains and strains of back and neck injuries & poisonings Both 0.1262 1.05 0.987,1.11 1175 11729 0.0871 1.05 0.992,1.12 1131 11381
842 Other sprains and strains injuries & poisonings Both 0.7568 1.01 0.949,1.08 1079 10729 0.7447 1.01 0.949,1.08 1052 10409
850 Hemorrhage or hematoma complicating a procedure injuries & poisonings Both 0.9863 1.0 0.953,1.05 1807 18037 0.778 1.01 0.959,1.06 1703 17465
851 Complications of transplants and reattached limbs injuries & poisonings Both 0.7943 0.99 0.921,1.07 797 7958 0.9616 1.0 0.93,1.08 764 7723
853 Complication of colostomy or enterostomy injuries & poisonings Both 0.8511 1.01 0.912,1.12 398 3977 0.912 0.993 0.882,1.12 289 3869
854 Complications of cardiac/vascular device, implant, and graft injuries & poisonings Both 0.4853 1.02 0.967,1.07 1537 15333 0.6026 1.01 0.961,1.07 1424 14875
855 Complication of nervous system device, implant, and graft injuries & poisonings Both 0.278 1.07 0.944,1.22 254 2540 0.3451 1.06 0.935,1.21 250 2463
856 Vascular complications of surgery and medical procedures injuries & poisonings Both 0.335 0.94 0.829,1.07 262 2617 0.3357 0.939 0.827,1.07 257 2524
857 Mechanical complication of unspecified genitourinary device, implant, and graft injuries & poisonings Both 0.3296 0.971 0.915,1.03 1196 11925 0.399 0.974 0.916,1.04 1131 11585
858 Complication of internal orthopedic device injuries & poisonings Both 0.7129 0.991 0.946,1.04 1892 18846 0.6516 0.989 0.943,1.04 1859 18320
859 Complication due to other implant and internal device injuries & poisonings Both 0.7925 0.994 0.947,1.04 1820 18191 0.5023 0.983 0.936,1.03 1741 17660
870 Open wounds of head; neck; and trunk injuries & poisonings Both 0.7998 1.0 0.97,1.04 3389 30552 0.2228 0.886 0.73,1.08 100 1135
870.1 Open wound or laceration of eye or eyelid injuries & poisonings Both 0.1309 1.13 0.964,1.33 156 1551 0.1079 1.14 0.971,1.34 150 1498
870.2 Open wound of ear injuries & poisonings Both 0.1479 0.871 0.723,1.05 114 1131 0.1442 0.868 0.718,1.05 110 1093
870.3 Other open wound of head and face injuries & poisonings Both 0.3793 1.03 0.966,1.09 1064 10560 0.3467 1.03 0.968,1.1 1035 10226
870.4 Open wound of nose and sinus injuries & poisonings Both 0.0302 0.842 0.721,0.983 168 1667 0.02951 0.839 0.717,0.983 162 1621
870.5 Open wound of lip and mouth injuries & poisonings Both 0.9016 0.992 0.869,1.13 230 2293 0.8318 0.986 0.863,1.13 222 2200
870.6 Open wound of neck injuries & poisonings Both 0.271 1.08 0.938,1.25 184 1833 0.3342 1.08 0.928,1.25 178 1777
870.8 Open wound of genital organs injuries & poisonings Both 0.2742 0.904 0.755,1.08 117 1170 0.2228 0.886 0.73,1.08 100 1135
871 Open wounds of extremities injuries & poisonings Both 0.6353 1.01 0.971,1.05 2705 26585 0.6368 0.964 0.826,1.12 182 1841
871.1 Open wound of hand except finger(s) injuries & poisonings Both 0.695 0.98 0.887,1.08 438 4378 0.526 0.968 0.874,1.07 422 4254
871.2 Open wound of finger(s) injuries & poisonings Both 0.6237 0.981 0.909,1.06 731 7291 0.6166 0.981 0.908,1.06 710 7076
871.3 Open wound of foot except toe(s) alone injuries & poisonings Both 0.8279 1.01 0.906,1.13 331 3277 0.8204 1.01 0.905,1.13 318 3165
871.4 Open wound of toe(s) injuries & poisonings Both 0.877 0.988 0.851,1.15 191 1901 0.6368 0.964 0.826,1.12 182 1841
872 Traumatic amputation injuries & poisonings Both 0.9247 1.0 0.909,1.11 415 4129 0.9036 1.01 0.909,1.11 406 4005
873 Broken tooth injuries & poisonings Both 0.6531 0.962 0.812,1.14 148 1471 0.7261 0.97 0.816,1.15 142 1422
874 Complication of amputation stump injuries & poisonings Both 1.0 1.0 0.829,1.21 122 1220 0.9226 1.01 0.836,1.22 121 1184
875 Non-healing surgical wound injuries & poisonings Both 0.7178 1.02 0.927,1.12 495 4950 0.9661 0.998 0.908,1.1 472 4799
876 Posttraumatic wound infection not elsewhere classified injuries & poisonings Both 0.2427 1.05 0.969,1.13 669 6680 0.3041 1.04 0.962,1.13 621 6461
907 Injuries to the nervous system injuries & poisonings Both 0.4989 0.976 0.911,1.05 888 8852 0.526 0.978 0.912,1.05 873 8553
910 Superficial injury, infected injuries & poisonings Both 0.859 0.981 0.792,1.21 89 887 0.9795 0.997 0.8,1.24 84 855
911 Blister injuries & poisonings Both 0.5943 1.04 0.897,1.21 185 1838 0.3733 1.07 0.92,1.25 177 1760
912 Insect bite injuries & poisonings Both 0.1854 1.08 0.963,1.21 321 3207 0.1644 1.09 0.967,1.22 311 3105
913 Toxic effect of venom injuries & poisonings Both 0.1563 0.91 0.799,1.04 247 2461 0.208 0.919 0.806,1.05 240 2355
915 Superficial injury without mention of infection injuries & poisonings Both 0.8035 1.01 0.964,1.05 2368 23457 0.7889 1.01 0.963,1.05 2276 22709
916 Contusion injuries & poisonings Both 0.3715 1.02 0.98,1.05 3199 30228 0.2163 1.02 0.986,1.06 3073 29287
930 Allergic reaction to food injuries & poisonings Both 0.3162 1.04 0.96,1.14 597 5953 0.4955 1.03 0.945,1.12 564 5802
931 Contact dermatitis and other eczema due to plants [except food] injuries & poisonings Both 0.4977 0.97 0.888,1.06 530 5290 0.4315 0.964 0.881,1.06 506 5142
938 Dermatitis due to solar radiation injuries & poisonings Both 0.5309 0.99 0.957,1.02 4197 24407 0.6887 0.993 0.959,1.03 3820 23250
938.1 Acute dermatitis due to solar radiation injuries & poisonings Both 0.1503 1.12 0.959,1.32 164 1640 0.125 1.13 0.966,1.33 161 1597
938.2 Chronic dermatitis due to solar radiation injuries & poisonings Both 0.5559 0.99 0.957,1.02 4001 24007 0.6887 0.993 0.959,1.03 3820 23250
941 Adverse reaction to serum or vaccine injuries & poisonings Both 0.6237 1.04 0.878,1.24 140 1400 0.7943 1.02 0.856,1.22 131 1360
942 Infusion and transfusion reaction injuries & poisonings Both 0.4027 0.942 0.819,1.08 221 2205 0.3707 0.936 0.81,1.08 208 2122
946 Anaphylactic shock NOS injuries & poisonings Both 0.8831 1.01 0.909,1.12 385 3830 0.9226 0.995 0.895,1.11 371 3726
947 Urticaria injuries & poisonings Both 0.673 1.01 0.947,1.09 889 8845 0.6714 1.02 0.946,1.09 857 8599
949 Allergies, other injuries & poisonings Both 0.2512 0.983 0.954,1.01 5269 26807 0.2844 0.983 0.954,1.01 5054 26047
952 Spinal cord injury without evidence of spinal bone injury injuries & poisonings Both 0.9183 1.01 0.909,1.11 419 4176 0.9661 1.0 0.906,1.11 409 4039
957 Injury to other and unspecified nerves injuries & poisonings Both 0.5821 0.945 0.771,1.16 116 1150 0.6397 0.952 0.776,1.17 113 1119
958 Certain early complications of trauma or procedure injuries & poisonings Both 0.5309 1.02 0.958,1.09 1073 10721 0.3606 1.1 0.892,1.37 90 877
958.1 Postoperative shock injuries & poisonings Both 0.456 1.07 0.896,1.28 133 1325 0.4853 1.07 0.887,1.29 116 1287
958.2 Traumatic and surgical subcutaneous emphysema injuries & poisonings Both 0.3802 1.1 0.89,1.36 92 911 0.3606 1.1 0.892,1.37 90 877
960 Poisoning by antibiotics injuries & poisonings Both 0.4036 0.981 0.938,1.03 2108 18753 0.7907 0.992 0.938,1.05 1346 13493
960.1 Adverse effects of antibacterials (not penicillins) injuries & poisonings Both 0.4426 0.939 0.8,1.1 158 1552 0.3206 0.918 0.776,1.09 144 1508
960.2 Allergy/adverse effect of penicillin injuries & poisonings Both 0.5781 0.985 0.932,1.04 1414 13864 0.7907 0.992 0.938,1.05 1346 13493
961 Poisoning by other anti-infectives injuries & poisonings Both 0.01905 0.891 0.809,0.981 470 4694 0.1698 1.05 0.98,1.12 890 8933
961.1 Poisoning/allergy of sulfonamides injuries & poisonings Both 0.3963 1.03 0.963,1.1 939 9190 0.1698 1.05 0.98,1.12 890 8933
962 Poisoning by hormones and synthetic substitutes injuries & poisonings Both 0.2735 0.953 0.874,1.04 561 5601 0.8492 1.01 0.897,1.14 290 2948
962.1 Adrenal cortical steroids causing adverse effects in therapeutic use injuries & poisonings Both 0.1489 0.919 0.819,1.03 308 3069 0.1807 0.923 0.821,1.04 293 2991
962.3 Hormones and synthetic substitutes causing adverse effects in therapeutic use injuries & poisonings Both 0.9817 1.0 0.89,1.13 305 3029 0.8492 1.01 0.897,1.14 290 2948
963 Poisoning by primarily systemic agents injuries & poisonings Both 0.05012 1.05 1.0,1.09 2031 19919 0.06607 1.05 0.997,1.1 1781 18982
963.1 Antineoplastic and immunosuppressive drugs causing adverse effects injuries & poisonings Both 0.06166 1.04 0.998,1.09 1980 19507 0.06607 1.05 0.997,1.1 1781 18982
964 Poisoning by agents primarily affecting blood constituents injuries & poisonings Both 0.2148 0.945 0.863,1.03 538 5360 0.3443 0.955 0.869,1.05 478 4904
964.1 Anticoagulants causing adverse effects injuries & poisonings Both 0.1514 0.935 0.852,1.03 509 5070 0.3443 0.955 0.869,1.05 478 4904
965 Poisoning by analgesics, antipyretics, and antirheumatics injuries & poisonings Both 0.6368 0.982 0.911,1.06 753 7525 0.6368 0.95 0.768,1.18 94 942
965.1 Opiates and related narcotics causing adverse effects in therapeutic use injuries & poisonings Both 0.0182 0.934 0.882,0.988 1305 12848 0.02344 0.934 0.881,0.991 1222 12506
965.3 Salicylates causing adverse effects in therapeutic use injuries & poisonings Both 0.5508 0.938 0.761,1.16 98 967 0.6368 0.95 0.768,1.18 94 942
966 Poisoning by anticonvulsants and anti-Parkinsonism drugs injuries & poisonings Both 0.7464 1.04 0.826,1.31 86 850 0.5297 1.08 0.853,1.36 82 830
967 Adverse effects of sedatives or other central nervous system depressants and anesthetics injuries & poisonings Both 0.07586 0.943 0.883,1.01 1000 9986 0.08913 0.944 0.883,1.01 956 9741
969 Poisoning by psychotropic agents injuries & poisonings Both 0.7345 0.977 0.855,1.12 234 2331 0.8128 0.984 0.859,1.13 228 2292
971 Poisoning by drugs primarily affecting the autonomic nervous system injuries & poisonings Both 0.235 0.845 0.64,1.12 56 546 0.257 0.852 0.645,1.12 56 529
972 Poisoning by agents primarily affecting the cardiovascular system injuries & poisonings Both 0.7674 1.02 0.89,1.17 228 2269 0.8279 0.975 0.777,1.22 81 835
972.1 Cardiac rhythm regulators causing adverse effects in therapeutic use injuries & poisonings Both 0.1047 1.23 0.958,1.58 66 637 0.1227 1.23 0.945,1.61 57 607
972.6 Antihypertensive agents causing adverse effects injuries & poisonings Both 0.8222 0.975 0.781,1.22 86 860 0.8279 0.975 0.777,1.22 81 835
974 Poisoning by water, mineral, and uric acid metabolism drugs injuries & poisonings Both 0.7727 0.969 0.784,1.2 90 896 0.8851 0.984 0.793,1.22 86 868
975 Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system injuries & poisonings Both 0.4624 0.914 0.72,1.16 69 686 0.5188 0.924 0.727,1.17 69 673
976 Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs injuries & poisonings Both 0.5728 1.08 0.834,1.39 60 600 0.6026 1.07 0.826,1.39 58 581
977 Personal history of allergy to medicinal agents injuries & poisonings Both 0.9247 1.0 0.952,1.06 1565 14843 0.859 1.0 0.952,1.06 1472 14431
979 Adverse drug events and drug allergies injuries & poisonings Both 0.5309 1.01 0.97,1.06 2116 20636 0.7079 1.01 0.964,1.06 2005 20110
989 Toxic effect of other substances, chiefly nonmedicinal as to source injuries & poisonings Both 0.03802 0.8 0.648,0.988 91 904 0.03548 0.792 0.638,0.984 86 875
990 Effects radiation NOS injuries & poisonings Both 0.3148 1.02 0.981,1.06 2707 23906 0.4571 1.02 0.975,1.06 2456 23183
994 Sepsis and SIRS injuries & poisonings Both 0.2443 1.03 0.98,1.08 1724 17160 0.6109 1.03 0.93,1.13 435 4673
994.1 Systemic inflammatory response syndrome (SIRS) injuries & poisonings Both 0.1845 1.09 0.959,1.24 248 2472 0.1033 1.12 0.977,1.28 225 2402
994.2 Sepsis injuries & poisonings Both 0.413 1.02 0.971,1.07 1636 16281 0.6109 1.03 0.93,1.13 435 4673
994.21 Septic shock injuries & poisonings Both 0.4592 1.04 0.944,1.14 484 4840 0.6109 1.03 0.93,1.13 435 4673
1000 Burns injuries & poisonings Both 0.413 1.03 0.954,1.12 638 6350 0.4207 1.03 0.952,1.12 609 6158
1001 Foreign body injury injuries & poisonings Both 0.2884 1.02 0.981,1.07 2372 22762 0.375 1.02 0.977,1.06 2251 21989
1002 Symptoms concerning nutrition, metabolism, and development injuries & poisonings Both 0.3404 1.01 0.985,1.05 4830 32603 0.4842 1.01 0.98,1.04 4482 31760
1004 Other signs and symptoms involving emotional state injuries & poisonings Both 0.9311 1.0 0.943,1.07 1136 11344 0.7834 0.991 0.931,1.06 1111 11007
1005 Other symptoms injuries & poisonings Both 0.04074 1.03 1.0,1.05 7724 30626 0.04898 1.03 1.0,1.05 7443 29712
1006 Crushing injury injuries & poisonings Both 0.7925 1.02 0.892,1.16 245 2437 0.7816 1.02 0.891,1.17 236 2360
1007 Injury to blood vessels injuries & poisonings Both 0.975 1.0 0.906,1.11 411 4106 0.7603 1.02 0.917,1.13 389 3968
1008 Crushing or internal injury to organs injuries & poisonings Both 0.6471 0.984 0.921,1.05 934 9331 0.4699 0.975 0.91,1.04 874 9028
1009 Injury, NOS injuries & poisonings Both 0.07943 1.02 0.998,1.05 9284 29063 0.02754 1.03 1.0,1.05 8965 28186
1010 Other tests injuries & poisonings Both 0.4426 0.992 0.972,1.01 19027 19331 0.5333 0.994 0.973,1.01 18261 18901
1011 Complications of surgical and medical procedures injuries & poisonings Both 0.9528 0.999 0.972,1.03 5922 32336 0.9638 1.0 0.973,1.03 5637 31426
1012 Late effect injuries & poisonings Both 0.3981 1.03 0.96,1.11 792 7909 0.2951 1.04 0.966,1.12 773 7628
1013 Asphyxia and hypoxemia injuries & poisonings Both 0.4446 0.984 0.944,1.03 2459 23709 0.399 0.982 0.941,1.02 2335 22870
1014 Effects of heat, cold and air pressure injuries & poisonings Both 0.3715 1.07 0.921,1.25 177 1770 0.5129 1.05 0.902,1.23 167 1707
1015 Effects of other external causes injuries & poisonings Both 0.9908 1.0 0.972,1.03 5744 32595 0.9772 1.0 0.971,1.03 5499 31644
1019 Other ill-defined and unknown causes of morbidity and mortality injuries & poisonings Both 0.5741 0.988 0.945,1.03 2208 21537 0.3631 0.979 0.936,1.02 2109 20732
1100 Family history injuries & poisonings Both 0.6266 1.04 0.901,1.19 222 2220 0.5093 1.05 0.909,1.21 204 2162
Download weights of GRCh37

LEGENDS

Figure 1: PheWAS results
P-values correspond to associations between the polygenic risk score (PRS) and the electronic health record-derived phenotype obtained using Firth’s logistic regression and also adjusting for age, gender, genotyping array, and the first four genotype principal components.
Upward (downward)-pointing triangles indicate a positive (negative) association.
Additional details are available by hovering the cursor over a particular triangle and by clicking the triangle. The horizontal dashed line indicates phenome-wide significance. Results are color-coded by disease category.

Figure 2: Exclusion PheWAS results
Results from a PheWAS performed using only subjects who never had the primary cancer diagnosis. The results are obtained as in Figure 1 but using the reduced dataset.

Figure 3: Associations between PRS and Selected Phenotype
This figure shows results for the selected phenotype in Figure 1.
This figure provides the beta estimate for the adjusted association between the PRS and the selected phenotype from Firth-corrected logistic regression. The corresponding confidence intervals are also shown. Results are presented for models using either a continuous or a categorical version of the PRS.
Q1 through Q4 represent the four quartiles of the PRS.

Loading…